A synergistic bioactive composition for vaginal health

A synergistic bioactive composition of Lactobacillus crispatus, Lactobacillus jensenii, Lactobacillus fermentum, and Lactoferrin effectively maintains vaginal health by enhancing adhesion and pathogen inhibition, addressing vaginal imbalances and infections.

WO2026115583A1PCT designated stage Publication Date: 2026-06-04SHARMA RADHIKA

Patent Information

Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
SHARMA RADHIKA
Filing Date
2025-11-29
Publication Date
2026-06-04

AI Technical Summary

Technical Problem

Existing vaginal health compositions fail to effectively maintain a balanced vaginal microbiota and ecosystem stability, particularly in addressing conditions like bacterial vaginosis and candidiasis, due to the lack of synergistic interactions among multiple bioactive components.

Method used

A synergistic bioactive composition comprising Lactobacillus crispatus, Lactobacillus jensenii, Lactobacillus fermentum, and Lactoferrin, formulated with pharmaceutically acceptable excipients, in specific CFU and milligram ranges, to support vaginal health and microbial balance.

Benefits of technology

The composition demonstrates enhanced adhesion to vaginal epithelial cells, improved inhibition of pathogens like Gardnerella vaginalis and Candida albicans, and maintains a stable vaginal pH, providing superior vaginal health benefits compared to individual components.

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Abstract

The present invention relates to a synergistic bioactive composition for women's health, and more particularly to compositions comprising Lactobacilli and Lactoferrin for supporting vaginal health. The invention specifically provides a composition comprising Lactobacillus crispatus, Lactobacillus jensenii, Lactobacillus fermentum, and Lactoferrin, formulated with one or more pharmaceutically acceptable excipients. The invention further pertains to compositions and kits intended for promoting a balanced vaginal microbiota, maintaining healthy vaginal conditions, and supporting overall vaginal ecosystem stability.
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