Perfusion module for a bioreactor, and system comprising a perfusion module and a bioreactor
The perfusion module for bioreactors addresses clogging and bio-fouling issues by optimizing fluid flow across the filter surface, ensuring gentle handling of biological material and enhancing media exchange, thus improving process efficiency and reducing contamination.
WO2026132106A2PCT designated stage Publication Date: 2026-06-25BIOTHRUST GMBH
Patent Information
- Authority / Receiving Office
- WO · WO
- Patent Type
- Applications
- Current Assignee / Owner
- BIOTHRUST GMBH
- Filing Date
- 2025-12-17
- Publication Date
- 2026-06-25
Smart Images

Figure EP2025087805_25062026_PF_FP_ABST
Abstract
The invention relates to a perfusion module (100, 400, 600, 900) for a bioreactor, comprising a main body (102, 402, 602, 902) having a fluid passage (110, 410, 610, 910) and a recess (112, 412, 612, 912) inclined toward said fluid passage (110, 410, 610, 910), a flow-permeable flow guidance element (104, 404, 604, 904), a filter element (106, 406, 606, 906), and at least one fastening element (108, 408, 608, 908), wherein the at least one fastening element (108, 408, 608, 908) is designed to fasten the filter element (106, 406, 606, 906) to the flow guidance element (104, 404, 604, 904), wherein, when the perfusion module (100, 400, 600, 900) is in an assembled condition, the flow guidance element (104, 404, 604, 904) is located between the main body (102, 402, 602, 902) and the filter element (106, 406, 606, 906), and the recess (112, 412, 612, 912) of the main body (102, 402, 602, 902) and the flow guidance element (104, 404, 604, 904) together form a cavity (200, 500, 700, 1000) that is connected to the fluid passage (110, 410, 610, 910) and to the flow guidance element (104, 404, 604, 904) such as to be flow-permeable.
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