Continuous cortisol sensor

The continuous cortisol sensor device addresses the challenge of non-continuous cortisol monitoring by using NAD(P)+-dependent enzymes and electrodes for real-time, accurate cortisol level detection, facilitating non-invasive, continuous measurement.

WO2026142759A1PCT designated stage Publication Date: 2026-07-02DEXCOM INC

Patent Information

Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
DEXCOM INC
Filing Date
2025-09-29
Publication Date
2026-07-02

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Abstract

Devices and methods for measurement of a hydroxysteroid analyte concentration in a host is provided, including a sensor housing, the sensor housing comprising an implantable analyte sensing portion configured to generate a signal associated with a concentration of a hydroxysteroid analyte, the analyte sensing portion comprising at least one (NAD(P)+)- dependent hydroxysteroid dehydrogenase enzyme; and at least one NAD(P)H oxidase. Detecting a signal corresponding to the hydroxysteroid analyte of the implantable portion after implantation of the implantable portion is also provided.
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