Chemical caries remover and method for preparing same

Abstract

The invention relates to a chemical caries remover formed by an activator gel and a regulator gel. The activator gel comprises an aqueous solution of sodium hypochlorite, the active ingredient of the composition. The regulator gel contains an aqueous solution comprising the amino acid L-glutamine, which reduces the effect of the hypochlorite on healthy tissue, a damaged-tissue disclosing agent and a fluorescent colouring agent. The chemical remover is prepared by mixing the two gels in the desired proportion, according to the type of caries to be treated.

Description

[0001] CHEMICAL CARIES REMOVER AND METHOD FOR ITS PREPARATION DESCRIPTIVE MEMORANDUM

[0002] The present invention falls within the field of dental products and methods. More precisely, the present invention belongs to the field of chemical caries removers using sodium hypochlorite; even more particularly, the invention relates to a fluorescent chemical caries remover composed of two solutions for identifying and chemically removing infected dentin.

[0003] Chemical caries removers are an alternative to conventional mechanical removal methods, which are often painful and imprecise for the patient. These chemical removers selectively dissolve infected dentin, thus avoiding unnecessary damage to healthy tooth structure.

[0004] PREVIOUS ART AND PROBLEMS TO SOLVE

[0005] Dental canker is a chronic, multifactorial disease that originates from the demineralization of enamel and dentin, the hard tissues that make up the tooth, due to the metabolic activity of bacteria present in the oral cavity. This disease is primarily induced by the interaction of bacteria with sugars and other fermentable carbohydrates present in the diet, which serve as substrates for their metabolism and the production of organic acids. In particular, bacteria such as Streptococcus mutans and Lactobacillus play a fundamental role in the development of canker, due to their ability to adhere to the enamel surface and form biofilms or dental plaque, which is the organic matrix where the acids that initiate the demineralization process are concentrated.

[0006] A cavity is damage to the enamel on the surface of the teeth, which occurs when acids from bacteria in the mouth attack this protective layer. This can cause a small hole to form in the enamel, potentially exposing the dentin underneath.

[0007] Dentin, unlike enamel, has a high collagen content, a structural protein that forms the organic matrix in which hydroxyapatite crystals, the main mineral of the tooth, are embedded. Approximately 70% of dentin is composed of minerals, 20% of organic material, primarily collagen, and the remaining 10% is water. When acid produced by bacteria reaches the dentin, this mineral matrix begins to dissolve, exposing the collagen network. As the collagen becomes vulnerable, bacterial proteases, along with hydrolases present in saliva and oral fluids, begin to degrade this organic structure. Specifically, collagenolytic enzymes attack the collagen fibrils, disintegrating the tooth's structural support, which leads to dentin collapse and the progression of caries to deeper layers.

[0008] The pathological process of dental caries begins when acids produced by bacteria lower the mouth's pH, which is normally neutral, below a critical threshold of 5.5. This corrosive environment causes the dissolution of minerals in the enamel, leading to the progressive loss of minerals such as calcium and phosphate across the entire tooth surface. Initially, this demineralization affects the outermost layers of enamel, causing opaque white spots, which may be the first visible clinical sign of caries. If left untreated at this early stage, the destructive process progresses to the inner layers of the enamel and eventually invades the dentin, the tissue beneath the enamel that is more vulnerable to acid destruction due to its lower degree of mineralization.When the organic matrix has been demineralized, collagen and other soft components are susceptible to enzymatic degradation, mainly by bacterial proteases and other hydrolases.

[0009] Regarding collagen degradation, two zones can generally be distinguished within a lesion. At the periphery of the lesion lies the affected dentin, which has been partially demineralized but retains intact collagen fibrils. This affected dentin, although weakened, has the capacity to remineralize if the bacterial load is eliminated. However, at the core of the lesion is the infected dentin, where the collagen has been completely destroyed due to the combined action of bacterial acids and enzymes. This infected dentin has no remineralization potential and must be removed to prevent the infection from progressing.

[0010] Tooth decay is not only a condition that affects the physical structure of the teeth, but it also has significant implications for a patient's overall health and quality of life. The presence of active, untreated decay can cause intense pain, hypersensitivity, secondary infections, and even abscesses when the bacterial infection penetrates the dental pulp, the soft, vital tissue of the tooth. The pain and discomfort caused by advanced decay directly impact the ability to chew, speak, and perform daily tasks, affecting a person's general well-being. Furthermore, in severe cases, the dental infection can spread to other tissues, leading to systemic complications.

[0011] The complexity of tooth decay also lies in the fact that its progression depends on multiple risk factors. These include poor oral hygiene, the composition and frequency of sugary foods consumed, saliva quality, genetic factors, and insufficient fluoride exposure. Fluoride is a key element in preventing tooth decay, as it strengthens the enamel structure and promotes remineralization. However, its effect is limited in advanced stages of decay, when the damage has already reached the deeper layers of the tooth.

[0012] In traditional caries treatments, infected dentin is mechanically removed using a high-speed drill. When caries are treated with these conventional, traumatic, and imprecise techniques, there is a risk of invading vital and healthy parts of the tooth and causing irreversible damage that requires further treatment. The dentist must use visual and tactile judgment to differentiate between infected and affected or healthy dentin, which is particularly difficult in deep cavities or hard-to-reach areas. The perception of tissue hardness using instruments is not always reliable, and errors in estimating the caries boundaries can lead to excessive dentin removal, compromising the structural integrity of the tooth.This lack of precision can lead to exposure of the dental pulp, which increases the risk of pulp infection and may require additional treatments, such as root canals or extractions, affecting the patient's long-term health and generating additional costs.

[0013] In cases of advanced caries, that is, when the lesion is very deep, these treatments are more time-consuming and problematic. The dentist needs a wider opening in the cavity to properly examine the infected area, and even then, it is difficult to determine the extent of the lesion. Lighting and visibility within the oral cavity are limited, especially in posterior areas or in mouths with a narrow opening, making it difficult to distinguish between healthy and infected dentin, and also challenging to determine whether the diseased tissue has been completely removed.

[0014] One of the main limitations of mechanical caries treatment is the invasive nature of the procedure. Caries removal with a drill, as explained, is a process that involves wearing down the tooth structure with a rotating tool that generates friction. This friction, in addition to wearing down the infected dentin, produces a considerable degree of pain and sensitivity in the patient, requiring, in most cases, the use of local anesthetics. This not only increases the procedure time but also involves potential side effects and discomfort for the patient, such as prolonged numbness and a general feeling of unease. In prolonged procedures or in patients with low pain tolerance, the administration of anesthesia may not even be sufficient to completely alleviate the discomfort, negatively impacting the treatment experience.

[0015] Furthermore, an additional disadvantage of these treatments is that patients perceive them as an intimidating procedure due to the noise and vibration of the dental drill. This negative perception can cause anxiety and aversion to dental treatments in pediatric and adult patients, or in those with previous traumatic experiences. In contrast, the atraumatic removal technique consists of removing only the infected (necrotic) dentin with manual instruments, leaving the affected dentin vital, which will regenerate through biological processes.

[0016] Atraumatic removal techniques can be combined with chemical removal, which involves applying various substances that soften the degraded tissue to facilitate its mechanical removal. These chemical solutions are effective in breaking down the collagen in infected dentin, allowing the necrotic tissue to soften and become easier to remove. However, the use of solutions with high concentrations of active agents is highly irritating and poses a risk of damage to adjacent healthy tissue. These substances can cause further degradation of healthy collagen by cleaving the polypeptide chains in its protein structure.

[0017] The main challenges of current chemical removers lie in their low proteolytic and tissue-softening power, limited bactericidal action, slow action, and chemical instability. Furthermore, in most cases, these chemical compounds do not discriminate between infected and healthy tissue, which implies a risk of further degradation of healthy dentin. To mitigate this problem, some products use reduced concentrations of active agents, but this affects their efficacy, as a concentration that is too low is not potent enough to completely break down infected dentin. Additionally, the breakdown of active agents, such as hypochlorite, can occur during storage or handling, further reducing their effectiveness when applied to the patient.

[0018] The dentist's work during a procedure in the patient's mouth is commonly hampered by poor lighting and difficulty distinguishing between healthy and damaged tissue. The lack of visible contrast between healthy and infected tissue makes it difficult to use chemical removers efficiently, increasing the risk of incomplete cavity removal.

[0019] Therefore, a chemical caries remover is needed that does not damage healthy dentin, allows for easy differentiation between healthy and damaged tissue within the relatively dark environment of the mouth, and is compatible with different types of cavities. It is also necessary to have a chemical remover with an efficient active agent that does not begin to degrade before use, as is currently the case with some well-known products.

[0020] OBJECT OF THE INVENTION

[0021] The object of the present invention is to provide a chemical caries remover that overcomes the drawbacks of the previous technique. In particular, the object of the present invention is to provide a chemical caries remover that does not cause discomfort to the patient and does not damage healthy dentin.

[0022] It is also another object of the present invention to provide a chemical dentin remover that identifies infected dentin for better visualization thereof and to provide a chemical remover that produces a fluorescence effect when exposed to halogen light, to improve visibility inside the patient's mouth. It is yet another object of the present invention to provide a chemical remover that is prepared in situ to avoid degradation of the active agent in contact with other substances.

[0023] Another object of the present invention is the preparation of the chemical remover by mixing two gels in different proportions to suit the needs of each type of cavity. More particularly, the present invention aims to provide a chemical remover that facilitates the work of dental professionals through a formulation that is easy to apply and handle in clinical practice, adaptable to various stages of caries, facilitates visualization of the infected tissue, and aids in its precise removal.

[0024] DETAILED DESCRIPTION OF THE INVENTION The present invention consists of a chemical caries remover formulated as two gels, an activating gel and a regulating gel, each containing specific ingredients carefully selected to act synergistically in the selective removal of infected dentin, ensuring the preservation of healthy dentin and improving the treatment experience. In a preferred embodiment of the present invention, to facilitate the preparation and identification of each component by the dental professional, the activating gel is transparent and the regulating gel is green. The function of each component in both gels and its contribution to the objectives of the invention are detailed below.

[0025] Activator Gel

[0026] The activator gel is an aqueous solution comprising mainly a sodium hypochlorite solution at 100 g / L (between 0.3% and 1% w / v total of the gel), sodium lauryl sulfate 30 (between 10% and 30% w / v total of the gel), dimethylamine oxide (between 5% and 15% w / v total of the gel) and sodium hydroxide at 50% w / v (between 0.1% and 0.3% w / v total of the gel).

[0027] Sodium hypochlorite is the key active agent in the activating gel, possessing an excellent capacity to break down collagen in infected dentin, facilitating its removal. A concentration of 0.5% w / v is sufficient to ensure effective degradation of carious dentin without being so high as to damage the surrounding healthy tissue. By using a concentration within this range, the invention minimizes the corrosive effects of the hypochlorite, maintaining an optimal balance between efficacy and safety for adjacent tissues.

[0028] Sodium lauryl sulfate (SLS) is a surfactant that facilitates the penetration of hypochlorite into carious tissue. Its inclusion allows the gel to better activate the tooth surface, promoting uniform contact between the active agent and the affected area. Choosing non-ethoxylated SLS reduces irritation compared to ethoxylated versions, ensuring a gentler application in the oral environment.

[0029] Dimethylamine oxide acts as a gelling and surfactant agent in an alkaline medium. In addition to its wetting and cleansing properties, dimethylamine oxide transforms the aqueous solution into a gel with the viscoelastic properties necessary for the remover to remain in place without running. This characteristic is essential to ensure that the hypochlorite remains in prolonged contact with the carious tissue, increasing its effectiveness and allowing for more controlled application by the professional. Furthermore, the gelling process prevents the sodium hypochlorite from coming into contact with other tissues and surfaces in the mouth, minimizing potential irritation.

[0030] Finally, sodium hydroxide adjusts the solution's pH to maintain an alkaline environment. Alkalinity is crucial for maximizing the stability and effectiveness of sodium hypochlorite, as this active agent decomposes more slowly under alkaline conditions, preserving its disinfectant and collagen-dissolving action upon application. The low concentration of sodium hydroxide prevents the pH from becoming too harsh on tissues, thus ensuring product safety.

[0031] Regulating Gel

[0032] The regulator gel consists of two phases, phase A and phase B. Phase A consists of an aqueous solution of the amino acid L-Glutamine (between 1% and 2% w / v total of the gel), urea (between 1% and 5% w / v total of the gel), developer (between 0.005% and 0.03% w / v total of the gel) and fluorescent dye in a 30% w / v solution (between 1% and 2% w / v total of the gel). Phase B is a composition of propylene glycol (between 5% and 15% w / v of the total gel), carboxymethylcellulose (between 1% and 3% w / v of the total gel), methylparaben (between 0.05% and 0.2% w / v of the total gel), and propylparaben (between 0.01% and 0.1% w / v of the total gel). In Phase A, the amino acid L-glutamine is a necessary component for the repair of biological tissues, and in the case of this composition, it forms an N-halo compound that decreases the irritability of chlorine in tissues and, in turn, reduces the corrosive effect of sodium hypochlorite on healthy tissues.Furthermore, by reducing the corrosive effect of hypochlorite on dentin, L-glutamine allows the remover to act selectively on the infected tissue, while preserving affected but remineralizable areas. This effect is one of the characteristics that distinguishes this chemical caries remover from those currently in use.

[0033] The presence of the amino acid necessitates the presentation in two separate gels, since when the amino acid comes into contact with the hypochlorite, it begins to degrade it. Other single-component removers have a higher concentration of hypochlorite due to its potential degradation. Urea performs a triple function in the buffering gel: First, it increases the ionic strength of the medium, achieving complete dissolution of the L-glutamine; second, it facilitates the debridement of necrotic tissue by acting as a softening agent, which allows for easier removal of carious tissue using a low concentration of sodium hypochlorite; and finally, it conditions the tissues, improving their receptivity to subsequent restorative materials.

[0034] For efficient work, the dentin to be removed must be identified. This is done using a tissue disclosing agent, preferably a non-toxic dye that selectively adheres to infected dentin, providing a visual contrast between healthy and damaged tissue. In a preferred embodiment, FD&C Blue #2 is used, which has proven particularly effective in identifying infected dentin by adhering specifically to affected areas. This differentiated visualization allows the dentist to accurately identify the area to be treated, reducing the risk of unnecessary removal of healthy dentin.

[0035] Additionally, to improve the sensitivity of detecting the infected dentin area, a food-grade fluorescent dye is used. This fluorescent dye allows for optimized visualization of the affected area under LED light, generating a light emission detectable by the human eye. This fluorescence mechanism allows for more precise and safer removal of infected dentin, especially in low-light conditions or in hard-to-reach areas. In a preferred embodiment, the fluorescent dye may be composed of a selection of food-grade dyes such as E100, E101, and E16, or a combination thereof, ensuring its safety and effectiveness in the oral environment.

[0036] The LED lamp provides thermosensitive regulation of proteolysis. Applying heat to the solution increases the kinetic energy of the molecules, allowing them to contact each other more quickly and disintegrate the surfaces they come into contact with in less time. This increased temperature enhances dentinization, bactericidal properties, and dissolution capabilities. This temperature increase does not affect the chemical stability of the solution until several hours later. Since the estimated reaction time of the solution with damaged dentin is 30 seconds, there is no need to worry about its stability.

[0037] Furthermore, in phase B, propylene glycol acts as a wetting agent, ensuring that the regulating gel maintains its consistency and adheres to the tooth surface. Its ability to retain water prevents the gel from dehydrating during application, ensuring prolonged and consistent action of the active components on the infected tissue.

[0038] Carboxymethylcellulose (CMC) is a thickening agent that forms a three-dimensional network in phase B of the regulating gel, providing the necessary structure and viscosity for the gel to adhere stably to the dentin. This three-dimensional network allows the other components of the gel, including the colorants and urea, to be distributed evenly, optimizing their effect and ensuring prolonged and effective contact with the infected tissue.

[0039] Finally, parabens are incorporated as preservatives in the formulation of the regulating gel. Methylparaben and propylparaben prevent the formation of microorganisms, particularly fungi and yeasts, ensuring the product's microbiological stability. Furthermore, the presence of these biocidal agents guarantees that the regulating gel maintains its quality and effectiveness during storage and until the time of use.

[0040] The synergistic action of both gels allows sodium hypochlorite to act in a controlled manner on carious tissue without affecting healthy dentin. By preparing the chemical remover on-site through the mixing of the gels in the appropriate proportion, it is ensured that the hypochlorite is in its most active state at the time of application, preventing premature degradation and optimizing its effectiveness in caries removal.

[0041] Method of Preparation and Use of Chemical Caries Remover

[0042] The present invention is designed not only to offer an effective and safe solution for treating caries, but also to facilitate its use in clinical practice, thereby optimizing the time and effort of the dental professional. The specific characteristics of its gel formulation, along with its fluorescent visualization capabilities, make this chemical remover an intuitive and efficient tool that improves application precision and ensures quality treatment with a reduced risk of error.

[0043] The gel consistency of both components, the activator gel and the regulator gel, allows the product to remain in the specific application area without running or dispersing to other areas of the oral cavity. This property is essential to ensure that the chemical remover acts exclusively on the infected dentin, avoiding contact with unwanted areas that could be affected by the active agents.

[0044] The gel texture also offers excellent handling during the procedure, allowing the dentist to apply the product in a controlled and precise manner with common dental tools, such as microapplicators or spatulas, eliminating the need for specialized equipment. This facilitates its integration into various dental practices without requiring significant changes to the instruments. The invention is based on a formulation of two separate gels, enabling simple and rapid preparation at the work site. These two components are mixed immediately before application to the cavity, ensuring that the sodium hypochlorite maintains its maximum efficacy at the time of use. The ease of this preparation minimizes preparation time and prevents degradation of the active agent, which is often a problem in single-component formulations stored for extended periods.

[0045] Furthermore, this methodology allows for adjusting the mixing ratio between the activator gel and the regulator gel according to the type of caries being treated, facilitating personalized treatment based on the severity of the lesion and the patient's needs. This flexible approach optimizes product use and ensures a treatment better suited to each clinical case.

[0046] In the case of treating a regular cavity, the gels should be mixed in equal parts. If it is an acute cavity, that is, a cavity in a specific location causing intense pain for the patient, the activator gel and regulator gel should be mixed in a 1:2 ratio. In the case of a chronic cavity, which is more common in adults, with a larger entry point and a darker color, the activator gel and regulator gel should be mixed in a 2:1 ratio. However, when evaluating the situation at the time of treatment, the dentist may choose any concentration within this range, depending on what they deem most appropriate to address the patient's specific problem.

[0047] For on-site preparation, clean, dry mixing instruments such as spatulas or microapplicators should be prepared, along with a small, sterile, non-porous mixing container or dish for combining the gels. Once the clinical determination of the type of canes to be treated has been made, and the ratio of gels to be mixed has been defined, the necessary quantities of each gel are measured according to the selected proportion.

[0048] The measured amounts of activator gel and regulator gel are placed in the clean mixing container and, using a spatula or applicator, the gels are mixed evenly until a homogeneous mixture is obtained. This process should be gentle and continuous to avoid incorporating air and to ensure that both gels are fully integrated.

[0049] The chemical remover mixture should be applied immediately to the infected dentin of the affected tooth. The active agent is most stable during the first 30 minutes, so it is essential to use a freshly prepared mixture to ensure maximum effectiveness.

[0050] Once applied directly to the infected dentin, wait approximately 30 seconds before beginning to remove the decayed tissue. This time is sufficient for the sodium hypochlorite to act on the degraded collagen of the affected dentin, facilitating the removal of the decay without damaging healthy tissue.

[0051] One of the most innovative aspects of this invention is the inclusion of a fluorescent dye in the regulating gel, which allows for optimized visualization of the infected dentin under LED light. This fluorescence technology facilitates the identification of damaged tissue, providing a clear and precise visual contrast between healthy and carious dentin. The dentist can thus immediately and visually verify the extent of the lesion, allowing for complete caries removal without unnecessarily enlarging the cavity.

[0052] After 30 seconds of contact, using dental tools such as dentin scoops or manual excavators, the dentin softened by the chemical remover is removed. The gel consistency of the product facilitates its effective action on the infected tissue, allowing it to be gently removed without the need for significant pressure.

[0053] After mechanical removal, it is essential to verify that all infected dentin has been removed by observing the treated area under LED light. Exposure to the light highlights any remaining carious tissue due to its fluorescent green pigmentation. If necessary, a second layer of the product can be applied to areas where carious tissue is still visible. Once the infected dentin has been removed, the area is cleaned with water, and the standard dental procedure is followed, culminating in restoration with any filling material. The compatibility of this formulation with dental restorative materials is another significant advantage. The urea and other components of the regulating gel condition the dental tissue, creating a surface that is more receptive to dental adhesives and other restorative materials applied after caries removal.This improves the adhesion and longevity of restorations, reducing the likelihood of sealing or leakage problems that could lead to new caries lesions in the future. This tissue conditioning allows caries treatment to not only be effective in removing infected tissue but also prepares the tooth to receive a durable and stable restoration.

[0054] This process ensures optimal preparation and application of the chemical remover, allowing the product to act effectively and in a controlled manner in the treatment of caries, improving both the precision of the treatment and the safety and comfort of the patient.

Claims

CLAIMS 1. A chemical caries remover CHARACTERIZED in that it comprises: an activating gel comprising an aqueous solution of between 0.3% and 1% w / v of sodium hypochlorite at 100g / L, between 10% and 30% w / v of non-ethoxylated sodium lauryl sulfate 30 (SLS), between 5% and 15% w / v of dimethylamine oxide and between 0.1% and 0.3% w / v of a 50% w / v sodium hydroxide solution; and a regulating gel comprising two phases, phase A and phase B; wherein phase A consists of an aqueous solution of between 1% and 2% w / v amino acid L-Glutamine, between 1% and 5% urea, between 0.005% and 0.03% w / v of a tissue developer and between 1% and 2% w / v of fluorescent dye in a 30% solution; wherein phase B is a formulation composed of between 5% and 15% w / v propylene glycol, between 1% and 3% w / v carboxymethylcellulose (CMC), between 0.05% and 0.2% w / v methylparaben and between 0.01% and 0.1% propylparaben.

2. The chemical caries remover according to claim 1 CHARACTERIZED in that: The activating gel consists of an aqueous solution of 0.5% w / v sodium hypochlorite at 100g / L, 20% w / v non-ethoxylated sodium lauryl sulfate 30 (SLS), 10% w / v dimethylamine oxide, and 0.2% w / v of a 50% w / v sodium hydroxide solution.

3. The chemical caries remover according to any of the preceding claims, CHARACTERIZED in that: Phase A of the regulating gel consists of an aqueous solution of 1.46% w / v amino acid L-Glutamine, 3% urea, 0.025% w / v tissue developer, and 1.5% w / v fluorescent dye in a 30% solution.

4. The chemical caries remover according to any of the preceding claims, CHARACTERIZED in that Phase B of the regulating gel is a compound formulation consisting of 10% w / v propylene glycol, 2% w / v carboxymethylcellulose (CMC), 0.1% w / v methylparaben, and 0.05% propylparaben.

5. The chemical remover according to any of the preceding claims CHARACTERIZED in that the tissue developer is a non-toxic dye.

6. The chemical caries remover according to any of the preceding claims CHARACTERIZED in that the tissue developer is FD&C Blue #2 dye.

7. The chemical caries remover according to any of the preceding claims CHARACTERIZED in that the fluorescent dye is selected from the group consisting of E100, E101 and E16 and / or a mixture thereof.

8. The chemical caries remover of any according to the preceding claims CHARACTERIZED in that the mixing ratio of activator gel to regulator gel is 1:

1.

9. The chemical caries remover of claims 1 to 7 CHARACTERIZED in that the mixing ratio of activator gel to regulator gel is 2:

1.

10. The chemical caries remover of claims 1 to 7 CHARACTERIZED in that the mixing ratio of activator gel to regulator gel is 1:

2.

11. The chemical caries remover of claims 1 to 7 CHARACTERIZED in that the mixing ratio of activator gel to regulator gel is any ratio between 2:1 and 1:

2.

12. A method for preparing the chemical remover of any one of the preceding claims, CHARACTERIZED in that it comprises the steps of: a) provide the activating gel comprising an aqueous solution of between 0.3% and 1% w / v of sodium hypochlorite at 100g / L, between 10% and 30% w / v of non-ethoxylated sodium lauryl sulfate 30 (SLS), between 5% and 15% w / v of dimethylamine oxide and between 0.1% and 0.3% w / v of a 50% w / v sodium hydroxide solution; (b) providing the buffer gel consisting of two phases, phase A and phase B; wherein phase A consists of an aqueous solution of between 1% and 2% w / v amino acid L-Glutamine, between 1% and 5% urea, between 0.005% and 0.03% w / v a tissue developer and between 1% and 2% w / v fluorescent dye in a 30% solution; and wherein phase B is a formulation composed of between 5% and 15% w / v propylene glycol, between 1% and 3% w / v carboxymethylcellulose (CMC), between 0.05% and 0.2% w / v methylparaben and between 0.01% and 0.1% propylparaben; and c) mix both gels until a homogeneous compound is obtained.

13. The method for preparing the chemical remover according to claim 12 CHARACTERIZED in that the mixture of step c) is made in a 1:1 ratio of activator gel to regulator gel.

14. The method for preparing the chemical remover according to claim 12 CHARACTERIZED in that the mixture of step c) is made in a 2:1 ratio of activator gel to regulator gel.

15. The method for preparing the chemical remover according to claim 12 CHARACTERIZED in that the mixture of step c) is made in a 1:2 ratio of activator gel to regulator gel.

16. The method for preparing the chemical remover according to claim 12 CHARACTERIZED in that the mixture of step c) is made in any proportion between 1:2 to 2:1 of activator gel to regulator gel.