Surgical Adhesives TRIZ Cases

Polysiloxane and silica-filled compositions transition from fluid delivery to in-situ gels for complete distal vessel occlusion.

Separate polysiloxane and hydride fluids use a catalyst to crosslink in situ, filling vascular spaces with controlled penetration.

S-polymer seals spinal tissue with durable flexibility and low inflammation.

A removable barrier keeps co-reactive dressing layers apart in moisture, preserving potency for effective hemostasis.

Hydrolysable ester crosslinks and catalytic compositions help spacers maintain spacing, then degrade in a controlled way.

A biomaterial sponge with hydrophilic reactive polymer forms a sealing gel with blood and tissue proteins for impaired coagulation.

A cross-linked liquid agent balances catheter delivery, gel formation, stable embolization, and precise positioning in microvessels.

A segmented catheter, plunger, and lock mechanism deliver biodegradable cyanoacrylate for consistent fallopian tube occlusion.

A release layer delivers neutralizer at the ostomy wafer to limit skin maceration and adhesive degradation from stoma output.

Honey-based calcium phosphate cement supports bone repair with less inflammation.

This case combines positive and negative Poisson's ratio layers with bioabsorbable fibers and pores for stronger tissue bonding.

This case uses adhesive-functionalized polymers to replace invasive fixation and maintain bonding strength in wet conditions.

This case combines staged crosslinking with freeze drying to form absorbent hydrogel structures that seal body punctures while controlling swelling.

A dual check valve applicator enables one-handed delivery with less hemostatic waste.

This case combines urethane and methyl methacrylate polymers for strong, biocompatible implant-to-bone adhesion with rapid curing.

Modified electrospraying creates spherical chitosan particles that maintain integrity and flow through medical devices to wounds.

A dual-syringe kit stabilizes thrombin and gelatin while reducing manual preparation before rapid bleeding control.

Hydrophilic polymers swell on wet tissues, enabling instant intermolecular and covalent crosslinking with strong adhesion.

Triggered ionic cross-linking of alginate pre-gels creates strong adhesion to wet tissues, eliminating the need for sutural fixation.

Adjustable bonding force in aqueous polyurethaneurea adhesives resolves the trade-off between strong adhesion and skin irritation during removal.

Injectable polymer particles fuse in situ to form a precise scaffold, eliminating the need for invasive surgical implantation.

A topical hemostatic powder uses a biodegradable superabsorbent polymer to rapidly absorb blood and form a gel.

Replacing bismuth subnitrate with micronized calcium stearate prevents mastitis without causing visual imperfections in dairy products.

Autologous fibrin sealants prepared without bovine thrombin ensure consistent quality and localized therapeutic delivery.

A malleable, biodegradable hemostatic agent composed of saturated glycerol esters and particulate fillers maintains mechanical stability at body temperature.

A conformable adhesive composition maintains shape retention and skin adhesiveness through a specific rubber polymer blend.

Albumin-based hydrogel solidifies at body temperature, preventing sclerosant washout by blood flow.

Polysiloxane adhesive incorporates hydrocolloid fillers to sustain bonding on moist skin.

Sprayable PEG-PLGA composition adheres to wet tissue without drying, eliminating allergic dermatitis and skin stripping risks.

Topical hemostatic composition travels through a catheter tract to seal distant arterial punctures, reducing hematoma risk and immobilization time.

Shear-activated nanotherapeutic aggregates disaggregate into nanoparticles under elevated shear stress to deliver vasodilating agents directly to collateral vessels.

A spring-loaded delivery device applies a powdered polymeric composition that forms a hydrogel upon contact with blood to promote hemostasis.

Replacing degenerated bone with resorbable regenerative material increases local bone mineral density without systemic medication side effects.

A biodegradable polyurethane polymer incorporates tissue-reactive functional groups to form covalent bonds with biological tissue.

Water-based compositions use water-insoluble ultraviolet absorbers to improve dirt pick-up resistance and stability.

Segmented multi-component adhesive system uses linked capsules to combine distinct substances for improved bonding strength and durability.

Segmenting hydrocolloid layers separates high initial moisture absorption from post-absorption cohesion, preventing adhesive disintegration and skin irritation.

Compressed gas propels hemostatic powder through a nozzle to cover wide bleeding areas, preventing recurrence without thermal damage.

Polymer sheets embed water-insoluble polyphosphates to trigger clotting without tissue damage or embolism risks from traditional powders.

Polyurethane-based putties eliminate exothermic tissue damage from PMMA cements while providing stable, nonabsorbable fracture fixation.

Rapid thiol-epoxy click reaction synthesizes poly(β-hydroxythioether) foams, overcoming slow traditional curing times while maintaining hydrolytic stability.

Mechanically interpenetrated nanofibers bonded to polymer substrates prevent bacterial adhesion on implantable medical devices.

Removing fibrinogen via precipitation prevents activity loss during isolation, enabling the generated thrombin to effectively clot platelet-rich plasma.

An rPDGF-loaded intermediary layer resolves microorganism colonization and interface stability issues to achieve complete periapical tissue regeneration.

Segmenting coagulation factors into separate components prevents spontaneous coagulation during storage while ensuring rapid clotting upon application.

A porous skin closure tape uses soluble adhesive traces to form drainage channels for wound exudates.

Epitaxial hydroxyapatite coating stabilizes calcium release in biphasic bone substitutes, preventing oversaturation and inflammation.