A method of measurement control for a sample analyzer and a sample analyzer

By providing sample TAT time mode and batch testing mode, the measurement process of the sample analyzer is optimized, which solves the shortcomings of compact instruments in terms of testing efficiency and accuracy, and achieves the effect of improving sample testing efficiency and accuracy without increasing resources.

CN110632330BActive Publication Date: 2025-11-07SHENZHEN MINDRAY BIO MEDICAL ELECTRONICS CO LTD +1
View PDF 3 Cites 0 Cited by

Patent Information

Application Number
CN201910810433.6
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2019-08-29
Publication Date
2025-11-07
Estimated Expiration
2039-12-23

AI Technical Summary

Technical Problem

Existing compact sample analyzers are insufficient in ensuring sample accuracy and batch testing speed, making it difficult to improve testing efficiency without expanding resources.

Method used

Two measurement modes are provided: sample TAT time mode and batch testing mode, which are used to achieve results for advanced samples first and results for the whole sample quickly, respectively. The measurement process is optimized by sample grouping, inter-group connection and measurement item sorting.

Benefits of technology

It achieves improved testing efficiency and accuracy of sample analyzers without increasing resources, meeting the requirements of different sample testing indicators.

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure CN110632330B_ABST
    Figure CN110632330B_ABST
Patent Text Reader

Abstract

The embodiment of the present application discloses a kind of sample analyzer measurement control method and sample analyzer, measurement control method is used to provide two kinds of measurement mode for measurement procedure selection, to meet different sample test index requirement.The embodiment of the present application method includes: obtaining the sample measurement demand of to-be-measured sample;When the sample measurement demand indicates sample detection turnaround time measurement mode, the to-be-measured sample is measured using sample detection turnaround time measurement mode to obtain measurement result, and the sample detection turnaround time measurement mode is used to realize the priority of first entering sample out measurement result;When the sample measurement demand indicates batch measurement mode, the to-be-measured sample is measured using batch test mode to obtain the measurement result, and the batch test mode is used to realize the whole sample simultaneously out measurement result.
Need to check novelty before this filing date? Find Prior Art

Description

TECHNICAL FIELD

[0001] The present application relates to the medical field, and in particular to a measurement control method of a sample analyzer and the sample analyzer. BACKGROUND

[0002] When a clinical user uses an existing coagulation analyzer with a fixed sample site structure to perform sample testing, the user often pays more attention to some key technical indicators of the instrument, such as sample value accuracy, sample turn-around time (TAT), and instrument batch testing speed. Sample value accuracy is the most core technical indicator of the instrument, and is a guarantee for screening and detection of coagulation function of patients before surgery, pregnant women before childbirth, patients with some coagulation factor abnormal diseases, and patients taking oral anticoagulants. Sample TAT time refers to the time required from sample suction to sample result output during sample testing. Batch testing speed refers to the number of samples that can be tested per unit time.

[0003] Sample analyzers on the market have already ensured sample value accuracy as a prerequisite. Sample analyzers in the mid-to-low-end market are mainly aimed at customer groups with a relatively small amount of daily sample testing. In view of development costs and sample amounts of users, manufacturers often design from aspects such as compressor component resource compression, single component resource sharing, and small volume ratio miniaturization to save resources and control costs. However, these clinical customers also hope to quickly and accurately analyze samples and output reports. The design of compact and economical analyzers often restricts sample TAT time and instrument batch testing speed technical indicators. Therefore, how to maximize testing efficiency under the premise of existing compact components without expanding additional resources has become a key to instrument measurement program design. SUMMARY

[0004] Embodiments of the present application provide a measurement control method of a sample analyzer and the sample analyzer, which are used to provide two measurement modes for measurement program selection to meet different sample testing index requirements.

[0005] In a first aspect, embodiments of the present application provide a measurement control method of a sample analyzer, which specifically includes: obtaining sample measurement requirements of a to-be-measured sample; when the sample measurement requirements indicate a sample detection turn-around time measurement mode (i.e., a TAT measurement mode, the same below), measuring the to-be-measured sample by using the sample detection turn-around time measurement mode to obtain a measurement result, and the sample detection turn-around time measurement mode is used to realize priority output of a measurement result of a sample that enters first.

[0006] When the sample measurement requirements indicate a batch measurement mode, the to-be-measured sample is measured by using the batch measurement mode to obtain the measurement result, and the batch measurement mode is used to realize simultaneous output of measurement results of all samples.

[0007] In a second aspect, the embodiments of the present application provide a sample analyzer, specifically comprising: an input device configured to acquire a sample measurement requirement of a sample to be measured; a processor configured to, when the sample measurement requirement indicates a sample detection turnaround time measurement mode, measure the sample to be measured in the sample detection turnaround time measurement mode to obtain a measurement result, the sample detection turnaround time measurement mode being configured to realize a first-in sample first-out measurement result; and when the sample measurement requirement indicates a batch measurement mode, measure the sample to be measured in the batch measurement mode to obtain the measurement result, the batch measurement mode being configured to realize a whole sample simultaneous measurement result.

[0008] From the above technical solutions, it can be seen that the embodiments of the present application have the following advantages: the sample analyzer provides two measurement modes, one being a sample TAT time mode and the other being a batch measurement mode. The sample TAT time mode is configured to realize a first-in sample first-out measurement result, and the batch measurement mode is configured to realize a whole sample simultaneous measurement result. Therefore, the sample analyzer can meet different sample test index requirements. BRIEF DESCRIPTION OF DRAWINGS

[0009] Figure 1 FIG. 1 is a structural block diagram of a sample analyzer according to an embodiment of the present application;

[0010] Figure 2 FIG. 2 is a regional diagram of the sample analyzer according to an embodiment of the present application;

[0011] Figure 3 FIG. 3 is another structural block diagram of the sample analyzer according to an embodiment of the present application;

[0012] Figure 4 FIG. 4 is a flow diagram of measuring a sample by the sample analyzer according to an embodiment of the present application;

[0013] Figure 5 FIG. 5 is an embodiment diagram of a measurement control method of the sample analyzer according to an embodiment of the present application;

[0014] Figure 6 FIG. 6 is another embodiment diagram of the measurement control method of the sample analyzer according to an embodiment of the present application;

[0015] Figure 7 FIG. 7 is another embodiment diagram of the measurement control method of the sample analyzer according to an embodiment of the present application;

[0016] Figure 8 FIG. 8 is an embodiment diagram of the sample analyzer according to an embodiment of the present application;

[0017] Figure 9 FIG. 9 is another embodiment diagram of the sample analyzer according to an embodiment of the present application. DETAILED DESCRIPTION

[0018] The embodiment of the present application provides a measurement control method of a sample analyzer and the sample analyzer, which are used for providing two measurement modes for measurement program selection to meet different sample test index requirements.

[0019] The terms "first", "second", "third", "fourth" and the like in the description and claims of the present application, and above drawings (if there are) are used to distinguish similar objects, and do not necessarily indicate a specific order or sequence. It should be understood that the data thus used can be interchanged under appropriate circumstances, so that the embodiments described herein can be implemented in other than the order illustrated or described herein. In addition, the terms "comprise" and "have" and any variations thereof, are intended to cover non-exclusive inclusion, for example, a process, method, system, product or device that includes a list of steps or units does not necessarily limit to those steps or units clearly listed, but can include other steps or units not clearly listed or inherent to these processes, methods, products or devices.

[0020] Figure 1 An exemplary structural block diagram of the sample analyzer 100 in the embodiment of the present application is shown. The sample analyzer 100 includes an input device 101, a processor 102 and an output device 103. In the embodiment, the input device 101 can be used to acquire sample measurement requirements of a sample to be measured; the processor 102 can be used to measure the sample to be measured by using a sample detection turnaround time measurement mode to obtain a measurement result when the sample measurement requirements indicate the sample detection turnaround time measurement mode, and the sample detection turnaround time measurement mode is used to realize that a sample entering first is given priority to output the measurement result; and the output device 103 can be used to output the measurement result.

[0021] In the embodiment of the present application, the output device 103 and the input device 101 of the sample analyzer 100 can be a touch display screen, a liquid crystal display screen, etc., and can also be a liquid crystal display, a television and other independent display devices independent of the sample analyzer 100, and can also be a display screen on a mobile phone, a tablet computer and other electronic devices.

[0022] In an example, a regional schematic diagram of the sample analyzer 100 can be as shown in Figure 2 The regions of the sample analyzer 100 can specifically include a cup feeding region, a sample region, a reagent region, a needle washing region, a pre-warming region, a measurement region and a waste cup region. In an example, a structural schematic diagram of the sample analyzer 100 can be as shown in Figure 3As shown, the component mechanism of the sample analyzer 100 may include: a sample dispensing mechanism, a reagent dispensing mechanism, a cup-carrying mechanism, a dispensing mechanism traveling assembly, and a cup-carrying mechanism traveling assembly. The sample dispensing mechanism and reagent dispensing mechanism, in cooperation with the dispensing mechanism traveling assembly, can achieve movement in three forward and reverse directions (X, Y, Z). The cup-carrying mechanism traveling assembly can achieve movement in two forward and reverse directions (Y, Z). The cup-carrying mechanism can move a new measuring cup in the X direction. Combined with... Figure 2 and Figure 3 The sample adding process in the sample analyzer 100 shown is as follows: First, the cup transport mechanism... Figure 2 The process is as follows: the sample incubation area picks up the measuring cup and places it in the pre-warming area; then, the sample dispensing mechanism draws the sample from the sample area and injects it into the measuring cup located in the pre-warming area; finally, the sample dispensing mechanism proceeds to the needle washing area for cleaning. The sample incubation process is as follows: the measuring cup containing the sample waits in the pre-warming area for a certain period; during this time, other components of the sample analyzer do not move. The buffer reagent addition process is as follows: the reagent dispensing mechanism draws buffer reagent from the reagent area and injects it into the measuring cup containing the sample in the pre-warming area; finally, the reagent dispensing mechanism proceeds to the needle washing area for cleaning. The buffer system incubation process is the same as the sample incubation process. The test reagent addition process is as follows: the cup transport mechanism moves the incubated measuring cup from the pre-warming area to the measurement area; then, the reagent dispensing mechanism draws the test reagent from the reagent area and injects it into the measuring cup located in the measurement area; finally, the reagent dispensing mechanism proceeds to the needle washing area for cleaning. The workflow for initiating the measurement process is as follows: Samples in the measurement area wait for a certain period before measurement. During this time, other components of the analyzer remain stationary for the sample being measured. The workflow for the discard / result reporting process is as follows: The cup-carrying mechanism moves the measuring cup from the measurement area to the discard area.

[0023] In one example, the process by which the sample analyzer 100 measures each sample is as follows: Figure 4 As shown, the specific process is as follows: The sample measurement stage is mainly divided into three stages, including the sample loading stage, the buffer reagent loading stage, and the test reagent loading stage. In the sample loading stage, after loading the measuring cup, the sample analyzer 100 injects the sample into the measuring cup. During the sample loading stage, depending on the measurement item or sample, the sample analyzer 100 can also selectively add diluent or corrective plasma, etc. After the sample loading stage is completed, the sample analyzer 100 determines whether the sample needs to be incubated according to actual needs. If sample incubation is not required, the sample analyzer 100 directly jumps to the test reagent loading stage; if sample incubation is required, the sample analyzer 200 can enter the buffer reagent loading stage, and then add different buffer reagents for different measurement items. For example... Figure 4As shown, the buffer reagent can include, but is not limited to, reagent R1, reagent R2 or reagent R3. It can be understood that if the sample analyzer 100 also includes a stirring area, the sample analyzer 100 can also select to perform a stirring action during the process of adding the buffer reagent. After the sample incubation is completed, the sample analyzer 100 injects a test reagent into the measuring cup, and then starts an optical method test sample or a magnetic bead method test sample to obtain a test result.

[0024] In an example, the measurement item can be routine coagulation seven items (such as activated partial thromboplastin time (APTT), prothrombintine (PT), thromboplastin time (TT), Fibrinogen (FIB), D-Dimer, Fibrinogen and Fibrin Degradation Products (FDP), and antithrombin-III (AT-III).

[0025] For details, please refer to Figure 5 As shown, an embodiment of the measurement control method of the sample analyzer in the present application specifically includes:

[0026] 501. The sample analyzer acquires a sample measurement requirement of a sample to be measured.

[0027] In the embodiment, the sample analyzer can acquire the sample measurement requirement of the sample to be measured through an input device. Specifically, according to different modes of the input device of the sample analyzer, the input mode of the sample measurement requirement is different. For example, as shown in Figure 6 As shown, the input device of the sample analyzer can be a touch screen, and the touch screen displays two options of sample TAT time measurement and batch measurement. Then the user inputs the sample measurement requirement by clicking the selection on the touch screen. In the embodiment, the sample measurement requirement can also be input in other ways, such as setting a measurement mode button to select the sample measurement requirement through the measurement mode button.

[0028] 502. When the sample measurement requirement indicates a sample TAT time measurement mode, the sample analyzer measures the sample to be measured in the sample TAT time measurement mode to obtain a measurement result.

[0029] In the embodiment, the sample TAT time measurement is used to realize "fast output of measurement result of sample with priority of sample entering first", that is, after a single sample enters, the sample measurement is performed on the single sample to obtain a measurement result.

[0030] 503. When the sample measurement needs to indicate the batch measurement mode, the sample analyzer measures the sample to be measured in the batch measurement mode to obtain a measurement result.

[0031] In the embodiment, the batch measurement mode is used to realize "fast output of measurement result of all samples in the whole batch". That is, after multiple samples enter, the multiple samples are measured, and the measurement results of the multiple samples are output simultaneously.

[0032] In the embodiment, the sample analyzer provides two measurement modes, a sample TAT time mode and a batch test mode. The sample TAT time mode is used to realize "fast output of measurement result of sample with priority of sample entering first", and the batch test mode is used to realize "fast output of measurement result of all samples in the whole batch". Therefore, the sample analyzer can meet different sample test index requirements.

[0033] The measurement control method of the sample analyzer in the batch measurement mode and the sample TAT time measurement mode will be described in detail below.

[0034] For details, please refer to Figure 6 In the embodiment, an embodiment of the measurement control method of the sample analyzer in the batch measurement mode is taken as an example, which includes the following steps.

[0035] 601. The sample analyzer groups the sample to be measured according to a sample grouping rule to obtain a sample group set, wherein the sample grouping rule includes dividing the sample to be measured with the same measurement item according to the sample quantity.

[0036] In this embodiment, the sample quantity is determined according to the processing capacity of the sample analyzer. Therefore, the sample analyzer also needs to obtain the corresponding sample quantity for different to-be-measured samples. The specific manner is as follows: the sample analyzer obtains the incubation time of each measurement item in the to-be-measured sample, determines the minimum incubation time as the minimum incubation time, obtains the injection time of a single sample and the sample buffer corresponding to the single sample, and obtains the processing capacity of the sample analyzer according to the minimum incubation time and the injection time, that is, the sample quantity of the sample analyzer when grouping. For example, the sample analyzer currently has 30 samples. Among them, 20 samples have the same measurement items (APTT, PT, TT, and FIB, respectively), and 10 samples have the same measurement items (APTT, PT, and TT, respectively). At this time, the sample analyzer obtains the incubation time of the four measurement items, and assumes that the incubation time of APTT is the minimum, which is 30 seconds. The sample analyzer obtains the injection time of a single sample and the sample buffer of the single sample, which is 3 seconds, and can determine that the sample quantity is 10 (that is, each sample group contains at most 10 samples). Therefore, the sample group set obtained by grouping the to-be-measured sample according to the sample grouping rule includes three sample groups, wherein the first sample group contains 10 samples, and the measurement items of the samples are APTT, PT, TT, and FIB; the second sample group contains 10 samples, and the measurement items of the samples are APTT, PT, TT, and FIB; and the third sample group contains 10 samples, and the measurement items of the samples are APTT, PT, and TT. On this basis, the parameter configuration of the sample group set can be as shown in Table 1:

[0037] Table 1

[0038]

[0039] In Table 1, “1” in the cell indicates that the measurement item of the sample group contains the measurement item, and “0” in the cell indicates that the measurement item of the sample group does not contain the measurement item. Table 1 can represent the sample grouping configuration of batch measurement.

[0040] 602, the sample analyzer uploads the sample groups in the sample group set to the sample analyzer for measurement to obtain measurement results, wherein after the reagent dispensing mechanism of the sample analyzer injects the same test reagent for the same measurement item of the same sample group, the reagent dispensing mechanism is cleaned.

[0041] It should be noted that the embodiment simultaneously uploads the sample groups of the same item to the sample analyzer for testing, so that the same test reagent is injected into the measuring cups corresponding to each sample of the sample groups during the reagent adding stage. Since the items tested by each sample are the same, the same reagent needs to be added, so the reagent needle does not need to be cleaned in between when adding the same reagent to each sample. After the test reagent is added to each measuring cup, the reagent needle is cleaned to add the next reagent. Therefore, compared with the existing sample-by-sample online testing, the embodiment tests in the form of a sample group, which can reduce the needle cleaning time when adding different reagents between samples. Taking 10 samples in a sample group as an example, each sample needs to add 2 kinds of reagents, so only the needle needs to be cleaned before adding the first reagent, and the needle needs to be cleaned once after adding the first reagent, and the needle needs to be cleaned after adding the second reagent, a total of 3 times. Compared with the prior art of 10 samples, the needle needs to be cleaned 21 times, which can greatly reduce the overall sample fast result time and improve the overall test efficiency.

[0042] In the embodiment, the sample analyzer can also obtain the inter-group connection of the sample groups and / or the inter-group connection of the measurement items, and then upload the sample groups in the sample group set to the sample analyzer for measurement to obtain measurement results. The inter-group connection of the sample groups is used to indicate the principle of uploading each sample group to the sample analyzer for measurement; the inter-group connection of the measurement items is used to indicate the principle of uploading each measurement item in the target sample group in the sample set to the sample analyzer.

[0043] Specifically, the principle indicated by the inter-group connection of the sample groups includes: the inter-group connection of the sample groups is used to indicate that after obtaining the measurement results of all measurement items of a first sample group in the sample group set, a second sample group in the sample group set is uploaded; or, the inter-group connection of the sample groups is used to indicate that after uploading a last measurement item of a first sample group in the sample group set, if there is available resource, a first measurement item of a second sample group in the sample group set is uploaded.

[0044] The principle indicated by the inter-group connection of the measurement items includes: the inter-group connection of the measurement items is used to indicate that after obtaining the measurement results of a third measurement item in the target sample group, a fourth measurement item of the target sample group is uploaded to the sample analyzer, and the fourth measurement item is uploaded after the third measurement item; or, the inter-group connection of the measurement items is used to indicate that after uploading a third measurement item in the target sample group, if there is available resource, a fourth measurement item of the target sample group is uploaded to the sample analyzer, and the fourth measurement item is uploaded after the third measurement item.

[0045] Based on the above scheme, in an example, if the inter-group connection of the sample group is used to indicate that the last measurement item of the first sample group in the sample group set is online, if there is available resource, the first measurement item of the second sample group in the sample group set is online, then the sample analyzer online the sample group in the sample group set for measurement to obtain measurement results in units of sample groups as follows:

[0046] The sample analyzer determines the last measurement item of the first sample group in the sample to be measured;

[0047] The sample analyzer loads the first measurement cup according to the number of samples of the first sample group. It can be understood that the number of the first measurement cup is 10. For convenience of description, the first measurement cup is identified according to the early and late loading time, which are measurement cup 1, measurement cup 2, measurement cup 3, measurement cup 4, measurement cup 5, measurement cup 6, measurement cup 7, measurement cup 8, measurement cup 9, and measurement cup 10. In the specific operation process, this operation may not be necessarily performed.

[0048] Then the sample analyzer uses the sample dispensing mechanism to suck the samples of the first sample group and inject them into the first measurement cup in sequence. After the samples in the first sample group are injected, the sample dispensing mechanism is cleaned. In the actual application, after the sample injection in the measurement cup 1 is completed, the timer of the measurement cup 1 starts to start, wherein the timing duration of the timer is the incubation duration of the samples in the first sample group. It can be understood that after the sample injection in the measurement cup 2 is completed, the timer of the measurement cup 2 also starts to start, and the timing duration of the timer is the incubation duration of the samples in the first sample group. Similarly, the timers of the measurement cups 3 to 10 also start to start in sequence after the sample injection is completed.

[0049] After the incubation time of the first sample in the first measuring cup expires, when the sample analyzer finds available resources in the pre-warming area, the sample analyzer loads the second measuring cup according to the number of samples in the second sample group. It can be understood that the number of the second measuring cup is 10. For the convenience of description, the second measuring cup is identified according to the early or late loading time, which is measuring cup 11, measuring cup 21, measuring cup 31, measuring cup 41, measuring cup 51, measuring cup 61, measuring cup 71, measuring cup 81, measuring cup 91, and measuring cup 101. The specific operation process may not necessarily have this operation. The specific loading process can be as follows: after the timer of the measuring cup 1 expires, the measuring cup 1 becomes the first expired measuring cup, the sample analyzer transfers the measuring cup 1 to the testing area, and uses the reagent dispensing mechanism to inject the corresponding testing reagent into the measuring cup 1 to measure the measurement result 1; after the measuring cup 1 is transferred to the testing area, the sample analyzer loads the first measuring cup (i.e., measuring cup 11) of the first measuring item of the second sample group to the position of the measuring cup 1 in the pre-warming area; after the timer of the measuring cup 2 expires, the sample analyzer transfers the measuring cup 2 to the testing area, and uses the reagent dispensing mechanism to inject the corresponding testing reagent into the measuring cup 2 to measure the measurement result 2; after the measuring cup 2 is transferred to the testing area, the sample analyzer loads the second measuring cup (i.e., measuring cup 21) of the first measuring item of the second sample group to the position of the measuring cup 2 in the pre-warming area. Similarly, after the timer of the measuring cup 3 expires, the sample analyzer transfers the measuring cup 3 to the testing area, and uses the reagent dispensing mechanism to inject the corresponding testing reagent into the measuring cup 3 to measure the measurement result 3; after the measuring cup 3 is transferred to the testing area, the sample analyzer loads the third measuring cup (i.e., measuring cup 31) of the first measuring item of the second sample group to the position of the measuring cup 3 in the pre-warming area. That is, as long as the pre-warming area of the sample analyzer has available empty positions (i.e., available resources), the sample analyzer can sequentially load the measuring cups of the first measuring item of the second sample group. After the second sample group is loaded, the samples in the second sample group are measured according to the measurement process to obtain the measurement results. In this embodiment, the samples in each sample group can be loaded according to the connection mode between the first sample group and the second sample group, and then the measurement results are obtained.

[0050] In an example, if the connection between the sample groups is used to indicate that the measurement results of all the measuring items of the first sample group in the sample group set are obtained, and then the second sample group in the sample group set is loaded, the sample analyzer loads the sample groups in the sample group set for measurement to obtain the measurement results, and the specific operation is as follows:

[0051] The sample analyzer determines the last measuring item of the first sample group in the sample to be measured;

[0052] The sample analyzer loads the first measuring cups in sequence according to the number of samples in the first sample group. It can be understood that the number of the first measuring cups is 10. For the convenience of description, the first measuring cups are identified according to the early or late loading time, which are measuring cup 1, measuring cup 2, measuring cup 3, measuring cup 4, measuring cup 5, measuring cup 6, measuring cup 7, measuring cup 8, measuring cup 9, and measuring cup 10. There is no such operation in the specific operation process.

[0053] Then the sample analyzer uses the sample dispensing mechanism to suck the samples in the first sample group and inject them into the first measuring cups in sequence, and cleans the sample dispensing mechanism after the samples in the first sample group are injected. After the timer of the measuring cup 1 expires, the sample analyzer transfers the measuring cup 1 to the test area and injects the corresponding test reagent into the measuring cup 1 using the reagent dispensing mechanism to measure and obtain the measurement result 1. After the timer of the measuring cup 2 expires, the sample analyzer transfers the measuring cup 2 to the test area and injects the corresponding test reagent into the measuring cup 2 using the reagent dispensing mechanism to measure and obtain the measurement result 2. Similarly, after the timer of the measuring cup 3 expires, the sample analyzer transfers the measuring cup 3 to the test area and injects the corresponding test reagent into the measuring cup 3 using the reagent dispensing mechanism to measure and obtain the measurement result 3. After the timer of the measuring cup 4 expires, the sample analyzer transfers the measuring cup 4 to the test area and injects the corresponding test reagent into the measuring cup 4 using the reagent dispensing mechanism to measure and obtain the measurement result 4. After the sample analyzer measures the samples in the first sample group according to the measurement process to obtain the measurement results (including measurement result 1 to measurement result 10), the sample analyzer measures the samples in the second sample group in the above-mentioned manner. In this embodiment, the samples in each sample group can be connected in the same way as the connection between the first sample group and the second sample group, and then the measurement results are obtained.

[0054] In an example, if the group connection of the measurement project indicates that the third measurement project in the target sample group is online after the third measurement project, if there is available resource, the fourth measurement project of the target sample group is online to the sample analyzer, and the fourth measurement project is online after the third measurement project. The sample analyzer specifically operates the online process of each measurement project in the sample group as follows:

[0055] The sample analyzer determines the third measurement project of the first sample group in the sample to be measured;

[0056] The sample analyzer loads the third measuring cups in turn according to the sample quantity of the first sample group, and it can be understood that the quantity of the third measuring cups is 10. For the convenience of description, the third measuring cups are identified according to the early and late loading time, which are measuring cup 12, measuring cup 22, measuring cup 32, measuring cup 42, measuring cup 52, measuring cup 62, measuring cup 72, measuring cup 82, measuring cup 92, and measuring cup 102, respectively. In the specific operation process, this operation is not necessarily performed.

[0057] Then the sample analyzer uses the sample dispensing mechanism to suck the samples in the first sample group and inject them into the third measuring cups in turn, and the sample dispensing mechanism is cleaned after the samples in the first sample group are injected. In this practical application, the timer of the measuring cup 12 starts to operate after the sample injection is completed in the measuring cup 12, and the timing duration of the timer is the incubation duration of the samples in the first sample group. It can be understood that the timer of the measuring cup 22 also starts to operate after the sample injection is completed in the measuring cup 22, and the timing duration of the timer is the incubation duration of the samples in the first sample group. Similarly, the timers of the measuring cups 32 to 102 are also started in turn after the sample injection is completed.

[0058] After the incubation time of the third measuring cup of the first sample is over, it becomes the second timeout measuring cup. When the sample analyzer finds available resources in the pre-warming area, it uploads the fourth measuring item of the first sample group, i.e., the sample analyzer uploads the fourth measuring cup according to the number of samples in the first sample group. It can be understood that the number of the fourth measuring cup is 10. For the convenience of description, the fourth measuring cup is identified according to the early or late loading time, which is measuring cup 13, measuring cup 23, measuring cup 33, measuring cup 43, measuring cup 53, measuring cup 63, measuring cup 73, measuring cup 83, measuring cup 93, and measuring cup 103. In the specific operation process, this operation may not be performed. The specific loading process can be as follows: after the timer of the measuring cup 12 is over, the sample analyzer transfers the measuring cup 12 to the testing area, and injects the corresponding testing reagent into the measuring cup 12 by using the reagent dispensing mechanism to measure the measuring result 12; after the measuring cup 12 is transferred to the testing area, the sample analyzer loads the first measuring cup (i.e., measuring cup 13) of the fourth measuring item of the first sample group to the position of the measuring cup 12 in the pre-warming area; after the timer of the measuring cup 22 is over, the sample analyzer transfers the measuring cup 22 to the testing area, and injects the corresponding testing reagent into the measuring cup 22 by using the reagent dispensing mechanism to measure the measuring result 22; after the measuring cup 22 is transferred to the testing area, the sample analyzer loads the third measuring cup (i.e., measuring cup 23) of the fourth measuring item of the first sample group to the position of the measuring cup 22 in the pre-warming area. In this way, after the timer of the measuring cup 32 is over, the sample analyzer transfers the measuring cup 32 to the testing area, and injects the corresponding testing reagent into the measuring cup 32 by using the reagent dispensing mechanism to measure the measuring result 32; after the measuring cup 32 is transferred to the testing area, the sample analyzer loads the fourth measuring cup (i.e., measuring cup 33) of the fourth measuring item of the first sample group to the position of the measuring cup 32 in the pre-warming area. That is, as long as the pre-warming area of the sample analyzer has available empty positions (i.e., available resources), the sample analyzer can sequentially upload the measuring cup of the next measuring item of the first sample group. After the next measuring item of the first sample group is uploaded, the samples in the first sample group are measured according to the measuring process to obtain the measuring results. In this embodiment, the measuring items in the same sample group can be sequentially uploaded in the inter-group connection mode between the third measuring item and the fourth measuring item, and then the measuring results are obtained.

[0059] In an example, if the inter-group connection of the measuring items is used to indicate that the fourth measuring item of the target sample group is uploaded to the sample analyzer after the measuring result of the third measuring item of the target sample group is obtained, and the fourth measuring item is uploaded after the third measuring item, the sample analyzer uploads the measuring items in the sample group in the following manner:

[0060] The sample analyzer determines a third measurement item of a first sample group in the sample to be measured;

[0061] The sample analyzer loads the third measurement cups in sequence according to the number of samples of the first sample group. It can be understood that the number of the third measurement cups is 10. For the convenience of description, the third measurement cups are identified according to the early and late loading time, which are measurement cup 12, measurement cup 22, measurement cup 32, measurement cup 42, measurement cup 52, measurement cup 62, measurement cup 72, measurement cup 82, measurement cup 92, and measurement cup 102. There is no such operation in the specific operation process.

[0062] Then the sample analyzer uses the sample dispensing mechanism to suck the samples of the first sample group and inject them into the third measurement cups in sequence, and cleans the sample dispensing mechanism after the samples in the first sample group are injected. After the timer of the measurement cup 12 expires, the sample analyzer transfers the measurement cup 12 to the test area and uses the reagent dispensing mechanism to inject the corresponding test reagent into the measurement cup 12 to measure and obtain the measurement result 12. After the timer of the measurement cup 22 expires, the sample analyzer transfers the measurement cup 22 to the test area and uses the reagent dispensing mechanism to inject the corresponding test reagent into the measurement cup 22 to measure and obtain the measurement result 22. In this way, after the timer of the measurement cup 32 expires, the sample analyzer transfers the measurement cup 32 to the test area and uses the reagent dispensing mechanism to inject the corresponding test reagent into the measurement cup 32 to measure and obtain the measurement result 32. After the timer of the measurement cup 42 expires, the sample analyzer transfers the measurement cup 42 to the test area and uses the reagent dispensing mechanism to inject the corresponding test reagent into the measurement cup 42 to measure and obtain the measurement result 42. After the sample analyzer measures the samples of the first sample group according to the measurement process and obtains the measurement results (including measurement result 12 to measurement result 102), the sample analyzer measures the samples of the next measurement item of the first sample group in the above-mentioned manner. In this embodiment, the samples of different measurement items in the same sample group can be connected in sequence like the connection between the third measurement item and the fourth measurement item, and then the measurement results are obtained.

[0063] It can be understood that the measurement items can also be sorted in this embodiment. Specifically, the measurement priority of each measurement item can be set in advance, and then the measurement items are arranged in sequence from high to low according to the priority. In one example, the item sorting in the measurement items can be as shown in Table 2:

[0064] Table 2

[0065] Measurement item APTT PT TT FIB D-Dimer FDP AT-III Priority 3 4 5 6 2 1 0

[0066] In Table 2, each number of priority is used to represent the line-up of the measurement item. For example, the "3" represents the line-up of the third measurement item, and the "4" represents the line-up of the fourth measurement item.

[0067] Optionally, in the embodiment, a time delay between each sample measurement item can also be set to prevent the sample analysis instrument from being overloaded due to the accumulation of sample line-up quantity. In an example, the configuration of the time delay can be as shown in Table 3:

[0068] Table 3

[0069]

[0070] In Table 3, the time delay configuration in the batch measurement mode can be used as an example, and the unit of time in Table 3 is second. For example, the time delay of the APTT measurement item is 40 seconds in any 4-item measurement item, and the time delay of the APTT measurement item is 50 seconds in any 6-item measurement item.

[0071] In the embodiment, the sample analysis instrument measures the samples in the batch measurement mode, thereby achieving the effect of "simultaneous measurement of the whole sample". At the same time, the sample grouping, item ordering, time delay, and group connection parameters of the sample to be measured are configured, thereby further compressing the measurement time and speeding up the measurement time.

[0072] For details, please refer to Figure 7 In the embodiment, the sample analysis instrument measures the samples in the batch measurement mode, thereby achieving the effect of "simultaneous measurement of the whole sample". At the same time, the sample grouping, item ordering, time delay, and group connection parameters of the sample to be measured are configured, thereby further compressing the measurement time and speeding up the measurement time.

[0073] 701、The sample analysis instrument groups the sample to be measured according to a sample grouping rule to obtain a sample group set, wherein the sample grouping rule is that a single sample is a sample group.

[0074] The sample analysis instrument groups the sample to be measured according to a sample grouping rule to obtain a sample group set, wherein the sample grouping rule is that a single sample is a sample group.

[0075] Table 4

[0076]

[0077] In Table 4, "1" in the cell indicates that the measurement item of the sample includes the measurement item, and "0" in the cell indicates that the measurement item of the sample does not include the measurement item.

[0078] 702、The sample analysis instrument groups the sample to be measured according to a sample grouping rule to obtain a sample group set, wherein the sample grouping rule is that a single sample is a sample group.

[0079] In this embodiment, the sample analyzer can also obtain the group-to-group connection between the single samples and / or the group-to-group connection of the measurement items, and then perform measurement on the sample analyzer in units of single samples to obtain measurement results. The group-to-group connection between the single samples is used to indicate the principle of performing measurement on the sample analyzer by each sample; and the group-to-group connection of the measurement items is used to indicate the principle of performing measurement on the sample analyzer by each measurement item in the sample.

[0080] Specifically, the group-to-group connection between the single samples specifically indicates the principle including: the group-to-group connection between the single samples is used to indicate that the first sample is performed measurement on all measurement items, and then the second sample is uploaded; or the group-to-group connection of the sample group is used to indicate that after the last measurement item of the first sample is uploaded, if there is available resource, the first measurement item of the second sample is uploaded.

[0081] The group-to-group connection of the measurement items specifically indicates the principle including: the group-to-group connection of the measurement items is used to indicate that the single sample is performed measurement on the third measurement item, and then the fourth measurement item of the single sample is uploaded to the sample analyzer, and the fourth measurement item is uploaded after the third measurement item; or the group-to-group connection of the measurement items is used to indicate that after the third measurement item of the single sample is uploaded, if there is available resource, the fourth measurement item of the single sample is uploaded to the sample analyzer, and the fourth measurement item is uploaded after the third measurement item.

[0082] Based on the above scheme, in an example, if the group-to-group connection of the sample group is used to indicate that after the last measurement item of the first sample is uploaded, if there is available resource, the first measurement item of the second sample is uploaded, the sample analyzer performs measurement on the sample analyzer in units of single samples to obtain measurement results, and the specific operation is as follows:

[0083] The sample analyzer determines the last measurement item of the first sample;

[0084] The sample analyzer loads the measurement cup A; then the sample analyzer uses the sample dispensing mechanism to suck the first sample into the measurement cup A, and cleans the sample dispensing mechanism after the first sample is injected; in this practical application, after the sample injection in the measurement cup A is completed, the timer of the measurement cup A starts to start, wherein the timing duration of the timer is the incubation duration of the first sample.

[0085] After the incubation time of the measuring cup A is over, the measuring cup A becomes the first timeout measuring cup. When there is available resource in the pre-warming area, the sample analyzer loads the second sample measuring cup B. The specific loading process can be as follows: after the timer of the measuring cup A is over, the sample analyzer transfers the measuring cup A to the testing area, and injects the corresponding testing reagent into the measuring cup A by using the reagent dispensing mechanism to measure and obtain the measurement result 1; after the measuring cup A is transferred to the testing area, the sample analyzer loads the second sample measuring cup B to the position of the measuring cup A in the pre-warming area. After the second sample is online, each sample of the second sample is measured according to the measurement process to obtain the measurement result. In this embodiment, each sample can be online in the group connection mode between the first sample and the second sample, and then the measurement result is obtained.

[0086] In an example, if the group connection between the single samples is used to indicate that the measurement result of all measurement items of the first sample is obtained, and then the second sample is online, the sample analyzer online the sample analyzer in the unit of the single sample to measure and obtain the measurement result, and the specific operation is as follows:

[0087] The sample analyzer determines the last measurement item of the first sample;

[0088] The sample analyzer loads the measuring cup A; then the sample analyzer sucks the first sample into the measuring cup A by using the sample dispensing mechanism, and cleans the sample dispensing mechanism after the first sample is injected; after the incubation time of the measuring cup A is over, the sample analyzer transfers the measuring cup A to the testing area, and injects the corresponding testing reagent into the measuring cup A by using the reagent dispensing mechanism to measure and obtain the measurement result 1. After the measurement result 1 is output, the sample analyzer loads the second sample measuring cup B and measures to obtain the measurement result 2. After the second sample is online, each sample of the second sample is measured according to the measurement process to obtain the measurement result. In this embodiment, each sample can be online in the group connection mode between the first sample and the second sample, and then the measurement result is obtained.

[0089] In an example, the group connection of the measurement items is used to indicate that after the third measurement item of the single sample is online, if there is available resource, the fourth measurement item of the single sample is online to the sample analyzer, and the fourth measurement item is online after the third measurement item, and the online process of each measurement item in the sample by the sample analyzer is as follows:

[0090] The sample analyzer determines a third measurement item of the first sample; the sample analyzer loads a measurement cup C according to the third measurement item of the first sample. Then the sample analyzer uses the sample dispensing mechanism to suck the first sample into the measurement cup C, and cleans the sample dispensing mechanism after the first sample is injected. In the actual application, after the sample injection in the measurement cup C is completed, the timer of the measurement cup C starts to start, wherein the timing duration of the timer is the incubation duration of the first sample.

[0091] After the timer of the measurement cup C expires, the measurement cup C becomes a second timeout measurement cup. The sample analyzer transfers the measurement cup C to the test area, and uses the reagent dispensing mechanism to inject the corresponding test reagent into the measurement cup C to obtain a measurement result C. After the measurement cup C is transferred to the test area, the sample analyzer loads a measurement cup D of a fourth measurement item of the first sample. After the timer of the measurement cup D expires, the sample analyzer transfers the measurement cup D to the test area, and uses the reagent dispensing mechanism to inject the corresponding test reagent into the measurement cup D to obtain a measurement result D. That is, as long as the pre-warming area of the sample analyzer has available empty positions (i.e., available resources), the sample analyzer can sequentially online the measurement cup of the next measurement item of the first sample. After the next measurement item of the first sample is online, the first sample is measured according to the measurement process to obtain a measurement result. In this embodiment, the online between different measurement items of the same sample group can be performed in the same way as the online between the third measurement item and the fourth measurement item, and then the measurement results are obtained.

[0092] In an example, if the group connection of the measurement items is used to indicate that after obtaining the measurement result of the third measurement item of a single sample, the fourth measurement item of the single sample is online to the sample analyzer, and the fourth measurement item is online after the third measurement item, the sample analyzer performs the online process of each measurement item in the sample as follows:

[0093] The sample analyzer determines a third measurement item of the first sample; the sample analyzer loads a measurement cup C according to the third measurement item of the first sample. Then the sample analyzer uses the sample dispensing mechanism to suck the first sample into the measurement cup C, and cleans the sample dispensing mechanism after the first sample is injected; after the incubation of the measurement cup C is completed, the sample analyzer transfers the measurement cup C to the test area, and uses the reagent dispensing mechanism to inject the corresponding test reagent into the measurement cup C to obtain a measurement result C; after obtaining the measurement result C, the sample analyzer loads a measurement cup D of a fourth measurement item of the first sample; after the timer of the measurement cup D expires, the sample analyzer transfers the measurement cup D to the test area, and uses the reagent dispensing mechanism to inject the corresponding test reagent into the measurement cup D to obtain a measurement result D. The sample analyzer can sequentially online the measurement cup of the next measurement item of the first sample. After the next measurement item of the first sample is online, the first sample is measured according to the measurement process to obtain a measurement result. In this embodiment, the measurement items in the same sample group can be online in the same way as the third measurement item and the fourth measurement item between groups, and then the measurement results are obtained.

[0094] It can be understood that the measurement items can also be sorted in the embodiment. Specifically, the measurement priority of each measurement item can be set in advance, and then the online order of the measurement items is arranged from high to low according to the priority. In an example, the item sorting in the measurement items can be as shown in Table 5:

[0095] Table 5

[0096] Measurement item APTT PT TT FIB D-Dimer FDP AT-III Priority 3 4 5 6 2 1 0

[0097] In Table 5, each number of the priority is used to represent the first online of the measurement item. For example, the "3" represents the third online of the measurement item, and the "4" represents the fourth online of the measurement item.

[0098] Optionally, the delay time between each sample measurement item can also be set in the embodiment, which is used to prevent the overload of the component resources of the sample analyzer caused by the accumulation of the sample online amount. In an example, the configuration of the delay time can be as shown in Table 6:

[0099] Table 6

[0100]

[0101] In the table 6, the time unit is second. For example, the APTT measurement item has a delay time of 0 second in any of the 4 measurement items; the APTT measurement item has a delay time of 0 second in any of the 6 measurement items.

[0102] In the embodiment, the sample analyzer measures the sample in the sample TAT time measurement mode, so as to achieve the effect of "the sample with advanced measurement result is measured first". Meanwhile, the parameters such as the configuration item order of the sample to be measured, the delay time and the group connection are configured, so as to further compress the measurement time and speed up the measurement time.

[0103] The measurement control method in the embodiment of the application is described above, and the sample analyzer in the embodiment of the application is described below.

[0104] For details, refer to Figure 8 As shown in the figure, the sample analyzer 800 in the embodiment of the application includes an input device 801, a processor 802 and an output device 803. The sample analyzer 800 can be the sample analyzer in the method embodiment described above, or one or more chips in the sample analyzer. The sample analyzer 800 can be used to perform part or all of the functions of the sample analyzer in the method embodiment described above.

[0105] For example, the input device 801 can be used to perform step 501 in the method embodiment described above. For example, the input device 801 obtains the sample measurement requirement of the sample to be measured.

[0106] The processor 802 can be used to perform steps 502 to 503 in the method embodiment described above, or to perform steps 601 to 602, or to perform steps 701 to 702. For example, when the sample measurement requirement indicates the sample detection turnaround time measurement mode, the processor 802 measures the sample to be measured in the sample detection turnaround time measurement mode to obtain a measurement result, and the sample detection turnaround time measurement mode is used to realize that the sample entering first is given priority to output the measurement result; when the sample measurement requirement indicates the batch measurement mode, the processor 802 measures the sample to be measured in the batch measurement mode to obtain the measurement result, and the batch measurement mode is used to realize that the overall sample is output simultaneously with the measurement result.

[0107] The output device 803 can be used to output the measurement result.

[0108] Optionally, the sample analyzer 800 further comprises a storage module coupled to the processor, so that the processor can execute computer-executable instructions stored in the storage module to implement the functions of the sample analyzer in the above method embodiments. In one example, the storage module optionally included in the sample analyzer 800 can be a storage unit within the chip, such as a register, a cache, etc. The storage module can also be a storage unit located outside the chip, such as a read-only memory (ROM) or other type of static storage device that can store static information and instructions, a random access memory (RAM), etc.

[0109] It should be understood that the above Figure 8 The processes performed between the modules of the sample analyzer in the corresponding embodiments are similar to the processes performed by the sample analyzer in the corresponding method embodiments described above, and will not be described here in detail. Figure 5 to Figure 7

[0110] Figure 9 A possible structural schematic diagram of a sample analyzer 900 in the above embodiments is shown, which can be configured as the sample analyzer described above. The sample analyzer 900 can include a processor 902, a computer-readable storage medium / memory 903, a transceiver 904, an input device 905, and an output device 906, and a bus 901. The processor, the transceiver, the computer-readable storage medium, etc. are connected through the bus. The specific connection medium between the above components is not limited by the embodiments of the present application.

[0111] In one example, the input device 905 obtains a sample measurement requirement of a sample to be measured;

[0112] When the sample measurement requirement indicates a sample detection turnaround time measurement mode, the processor 902 measures the sample to be measured in the sample detection turnaround time measurement mode to obtain a measurement result, and the sample detection turnaround time measurement mode is used to realize the priority of the first-entering sample in outputting the measurement result. When the sample measurement requirement indicates a batch measurement mode, the processor 902 measures the sample to be measured in the batch measurement mode to obtain the measurement result, and the batch measurement mode is used to realize the simultaneous output of the measurement result of the whole sample.

[0113] In one example, the processor 902 can include baseband circuitry, for example, which can generate control information.

[0114] In yet another example, the processor 902 can run an operating system to control the functions between various devices and components. The transceiver 904 can include baseband circuitry and radio frequency circuitry.

[0115] The input device 905, the output device 906, and the processor 902 can implement the above​Figure 5 to Figure 7 The corresponding steps in any of the embodiments above are specifically described here without redundancy.

[0116] It can be understood that, Figure 9 Only a simplified design of the sample analyzer is shown, and in actual applications, the sample analyzer can include any number of transceivers, processors, memories, etc., and all sample analyzers that can implement the present application are within the protection scope of the present application.

[0117] The processor 902 involved in the above sample analyzer 900 can be a general processor, such as a general central processing unit (CPU), a network processor (NP), a microprocessor, etc., or can be an application-specific integrated circuit (ASIC), or one or more integrated circuits for controlling program execution of the present application scheme. It can also be a digital signal processor (DSP), a field-programmable gate array (FPGA) or other programmable logic device, a discrete gate or transistor logic device, a discrete hardware component. The controller / processor can also be a combination of computing functions, such as a combination of one or more microprocessors, a combination of DSP and microprocessor, etc. The processor usually performs logical and arithmetic operations based on program instructions stored in memory.

[0118] The bus 901 involved above can be a peripheral component interconnect (PCI) bus or an extended industry standard architecture (EISA) bus, etc. The bus can be divided into an address bus, a data bus, a control bus, etc. For ease of representation, Figure 9 In any of the embodiments above, only one thick line is used to represent it, but it does not mean that there is only one bus or only one type of bus.

[0119] The computer-readable storage medium / memory 903 mentioned above can also store operating systems and other application programs. Specifically, the program can include program codes including computer operation instructions. More specifically, the above-mentioned memory can be a read-only memory (ROM), other types of static storage devices that can store static information and instructions, a random access memory (RAM), other types of dynamic storage devices that can store information and instructions, a disk memory, and the like. The memory 903 can be a combination of the above-mentioned storage types. And the above-mentioned computer-readable storage medium / memory can be in the processor, also can be outside the processor, or distributed on multiple entities including the processor or processing circuit. The above-mentioned computer-readable storage medium / memory can be embodied in a computer program product. For example, the computer program product can include a computer readable medium in a packaging material.

[0120] Alternatively, the embodiments of the present application also provide a general processing system, for example, commonly known as a chip, which includes: one or more microprocessors providing processor functions; and an external memory providing at least part of the storage medium, all of which are connected together with other support circuits through an external bus architecture. When the instructions stored in the memory are executed by the processor, the processor performs the functions of the sample analyzer in Figure 5 to Figure 7 The embodiments of the present application also provide a general processing system, for example, commonly known as a chip, which includes: one or more microprocessors providing processor functions; and an external memory providing at least part of the storage medium, all of which are connected together with other support circuits through an external bus architecture. When the instructions stored in the memory are executed by the processor, the processor performs the functions of the sample analyzer in Figure 5 steps 402 and 403 in Figure 6 steps 601 to 602 in Figure 7 steps 701 to 702 in

[0121] The steps of the methods or algorithms described in connection with the present disclosure can be embodied directly in hardware, in software executed by a processor, or in combinations of the two. The software instructions can be stored in a RAM memory, a flash memory, a ROM memory, an EPROM memory, an EEPROM memory, a register, a hard disk, a mobile disk, a CD-ROM, or any other form of storage medium known in the art. An exemplary storage medium is coupled to the processor such that the processor can read information from, and write information to, the storage medium. Of course, the storage medium can be a component of the processor. The processor and the storage medium can be located in an ASIC. Alternatively, the ASIC can be located in the sample analyzer. Of course, the processor and the storage medium can also exist as discrete components in the sample analyzer.

[0122] Those skilled in the art can clearly understand that, for the convenience and brevity of description, the specific working processes of the above-described system, device and unit can refer to the corresponding processes in the foregoing method embodiments, which will not be repeated here.

[0123] In several embodiments provided in the present application, it should be understood that the disclosed system, device and method can be implemented in other ways. For example, the above-described device embodiments are only schematic, for example, the division of the units is only a logical function division, and actual implementation can have another division manner, for example, a plurality of units or components can be combined or integrated into another system, or some features can be ignored or not executed. In addition, the coupling or direct coupling or communication connection between the units shown or discussed can be indirect coupling or communication connection through some interface, device or unit, and can be electrical, mechanical or other forms.

[0124] The units described as separate components can or can not be physically separate, and the components shown as units can or can not be physical units, that is, they can be located in one place, or can be distributed on a plurality of network units. Part or all of the units can be selected according to actual needs to achieve the purpose of the embodiment.

[0125] In addition, each functional unit in each embodiment of the present application can be integrated in one processing unit, or each unit can be physically present separately, or two or more units can be integrated in one unit. The integrated unit can be realized in the form of hardware or in the form of a software functional unit.

[0126] When the integrated unit is realized in the form of a software functional unit and sold or used as an independent product, it can be stored in a computer readable storage medium. Based on this understanding, the technical solutions of the present application essentially or the part that contributes to the prior art or the whole or part of the technical solutions can be embodied in the form of a software product. The computer software product is stored in a storage medium, and includes a plurality of instructions for causing a computer device (which can be a personal computer, a server, or a network device, etc.) to execute all or part of the steps of the methods described in the various embodiments of the present application. The foregoing storage medium includes: a U disk, a mobile hard disk, a read-only memory (ROM, Read-Only Memory), a random access memory (RAM, Random Access Memory), a magnetic disk or an optical disk, and various program code storage media.

[0127] The above-described embodiments are only used to illustrate the technical solutions of the present application, and not to limit them; although the present application has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that they can still modify the technical solutions recorded in the foregoing embodiments, or make equivalent replacements for part of the technical features; and these modifications or replacements do not make the essence of the corresponding technical solutions deviate from the spirit and scope of the technical solutions of the embodiments of the present application.

Claims

1. A measurement control method of a sample analyzer characterized by, The method comprises the following steps: acquiring sample measurement requirements of to-be-measured samples, the sample measurement requirements being used to indicate selection requirements of measurement modes proposed for the to-be-measured samples, the measurement modes comprising a sample detection turnaround time measurement mode and a batch measurement mode; when the sample measurement requirements indicate that the sample detection turnaround time measurement mode is adopted, configuring at least one parameter in a delay time of a measurement item, group connection of the measurement item, and group connection of a sample group for the sample group respectively formed by a single to-be-measured sample, and measuring the to-be-measured sample by using the at least one parameter configured in the sample detection turnaround time measurement mode to obtain a measurement result, the sample detection turnaround time measurement mode being used to realize priority of samples entering first; when the sample measurement requirements indicate that the batch measurement mode is adopted, dividing the to-be-measured samples with the same measurement item into a sample group, configuring at least one parameter in a delay time of a measurement item, group connection of the measurement item, and group connection of a sample group for the sample group, and measuring the to-be-measured sample by using the at least one parameter configured in the batch measurement mode to obtain the measurement result, the batch measurement mode being used to realize simultaneous output of the measurement result of the whole sample, wherein the delay time of the measurement item is used to indicate an online time interval between each measurement item in the sample group; the group connection of the measurement item is used to indicate that, after a measurement result of a third measurement item in a target sample group in a sample group set is obtained, a fourth measurement item of the target sample group is online to the sample analyzer, the fourth measurement item being online after the third measurement item; or, the group connection of the measurement item is used to indicate that, after a third measurement item in the target sample group is online, if there is available resource, a fourth measurement item of the target sample group is online to the sample analyzer, the fourth measurement item being online after the third measurement item; the group connection of the sample group is used to indicate that, after measurement results of all measurement items of a first sample group in a sample group set are obtained, a second sample group in the sample group set is online; or, the group connection of the sample group is used to indicate that, after a last measurement item of the first sample group in the sample group set is online, if there is available resource, a first measurement item of the second sample group in the sample group set is online.

2. The method of claim 1, wherein, The measurement of the to-be-measured sample by using the batch measurement mode to obtain the measurement result comprises the following steps: grouping the to-be-measured samples according to a sample grouping rule to obtain a sample group set, the sample grouping rule comprising dividing to-be-measured samples with the same measurement item according to sample quantity; onlineing the sample analyzer in units of sample groups in the sample group set for measurement to obtain the measurement result.

3. The method of claim 1, wherein, The inter-group connection of the sample groups is used to indicate that after the last measurement item of a first sample group in the sample group set is online, if there is available resource, the first measurement item of a second sample group in the sample group set is online, the measurement result of the sample group set according to the inter-group connection of the sample groups includes: determining a first measurement item of a first sample group and a second measurement item of a second sample group in the sample to be measured, the first measurement item being the last measurement item of the first sample group, and the second measurement item being the first measurement item of the second sample group; injecting the samples corresponding to the first measurement items into corresponding first measurement cups in sequence to start incubation; transferring the first timeout measurement cup in the first measurement cup that exceeds the incubation time to a test area for measurement to obtain a first measurement result; after the first timeout measurement cup is transferred to the test area, loading a second measurement cup of the second sample group to a position of the first timeout measurement cup in a pre-warming area to online the first measurement item of the second sample group to the sample analyzer, and obtaining a second measurement result; outputting the first measurement result and the second measurement result as the measurement result.

4. The method of claim 1, wherein, The inter-group connection of the measurement items is used to indicate that after a third measurement item in a sample group is online, if there is available resource, the fourth measurement item of the sample group is online to the sample analyzer, and the target measurement result of the target sample group obtained by measuring the target sample group according to the inter-group connection of the measurement items includes: determining the third measurement item and the fourth measurement item of the target sample group in the sample to be measured; injecting the samples corresponding to the third measurement items into corresponding third measurement cups in sequence to start incubation; transferring the second timeout measurement cup in the third measurement cup that exceeds the incubation time to a test area for measurement to obtain a third measurement result; after the second timeout measurement cup is transferred to the test area, loading a fourth measurement cup of the fourth measurement item to a position of the second timeout measurement cup in a pre-warming area to online the fourth measurement item to the sample analyzer, and obtaining a fourth measurement result; outputting the third measurement result and the fourth measurement result as the target measurement result.

5. The method according to any one of claims 2 to 4, characterized in that, The number of samples is determined by the processing capacity of the sample analyzer, and the processing capacity of the sample analyzer is used to indicate the number of samples processed by the sample analyzer within a sample incubation time.

6. The method of claim 5, wherein, The method further includes: obtaining the processing capacity of the sample analyzer.

7. The method of claim 6, wherein, The obtaining of the processing capacity of the sample analyzer includes: obtaining the minimum incubation time of each measurement item in the sample to be measured, and the injection time of a single sample and a sample buffer of the single sample; obtaining the processing capacity of the sample analyzer according to the minimum incubation time and the injection time.

8. The method according to any one of claims 2 to 4, characterized in that, The method further includes: obtaining the item order of each measurement item in the sample to be measured, the item order being used to indicate the online order of each measurement item in a sample group.

9. A sample analyzer characterized by, includes: An input device is configured to acquire sample measurement requirements of to-be-measured samples, the sample measurement requirements being used to indicate selection requirements of measurement modes proposed for the to-be-measured samples, the measurement modes including a sample detection turnaround time measurement mode and a batch measurement mode. A processor is configured to, when the sample measurement requirements indicate that the sample detection turnaround time measurement mode is adopted, configure at least one parameter in a delay time of a measurement item, group connection of the measurement item, and group connection of a sample group for each of the to-be-measured samples as a sample group, measure the to-be-measured samples by using the at least one parameter configured in the sample detection turnaround time measurement mode to obtain measurement results, and implement a first-in-first-out principle in the sample detection turnaround time measurement mode; when the sample measurement requirements indicate that the batch measurement mode is adopted, divide the to-be-measured samples with the same measurement item into a sample group, configure at least two parameters in a delay time of a measurement item, group connection of the measurement item, and group connection of a sample group for the sample group, measure the to-be-measured samples by using the at least two parameters configured in the batch measurement mode to obtain the measurement results, and implement a whole-sample-simultaneous-output principle in the batch measurement mode. The delay time of the measurement item is used to indicate an online time interval between each measurement item in the sample group. The group connection of the measurement item is used to indicate that, after a measurement result of a third measurement item in a target sample group in a sample group set is obtained, a fourth measurement item of the target sample group is online to the sample analyzer, and the fourth measurement item is online after the third measurement item; or, the group connection of the measurement item is used to indicate that, after a third measurement item in a target sample group is online, if there is available resource, a fourth measurement item of the target sample group is online to the sample analyzer, and the fourth measurement item is online after the third measurement item. The group connection of the sample group is used to indicate that, after measurement results of all measurement items in a first sample group in a sample group set are obtained, a second sample group in the sample group set is online; or, the group connection of the sample group is used to indicate that, after a last measurement item in the first sample group in the sample group set is online, if there is available resource, a first measurement item in a second sample group in the sample group set is online.

10. The sample analyzer of claim 9, wherein, The sample analyzer further includes a cup conveying mechanism, a sample dispensing mechanism, a reagent dispensing mechanism, a cleaning mechanism, a sample area, a pre-warming area, a testing area, a cup feeding area, and a reagent area. The processor is specifically configured to group the to-be-measured samples according to a sample grouping rule to obtain a sample group set, the sample grouping rule including dividing to-be-measured samples with the same measurement item according to sample quantity; and control the cup conveying mechanism to online the sample group set in the pre-warming area and the testing area for measurement, and obtain the measurement results.

11. The sample analyzer of claim 10, wherein, The inter-group connection of the sample groups is used to indicate that after the last measurement item of a first sample group in the sample group set is online, if there is available resource, the first measurement item of a second sample group in the sample group set is online, the processor is specifically configured to determine a first measurement item of the first sample group and a second measurement item of the second sample group in the sample to be measured, the first measurement item is the last measurement item of the first sample group, and the second measurement item is the first measurement item of the second sample group. The sample dispensing mechanism is controlled to inject the samples corresponding to the first measurement items from the sample area into corresponding first measurement cups in sequence, and then incubation is started. The cup conveying mechanism is controlled to transfer first timeout measurement cups in the first measurement cups that exceed an incubation time length to the test area for measurement, so as to obtain first measurement results. After the first timeout measurement cups are transferred to the test area, the cup conveying mechanism is controlled to load second measurement cups of the second sample group to positions of the first timeout measurement cups in the pre-warming area, so as to online the first measurement item of the second sample group to the sample analyzer, and obtain second measurement results. The sample analyzer further includes an output device configured to output the first measurement results and the second measurement results as the measurement results.

12. The sample analyzer of claim 10, wherein, In the inter-group connection of the measurement items, after a third measurement item in a sample group is online, if there is available resource, a fourth measurement item of the sample group is online to the sample analyzer, the processor is specifically configured to determine the third measurement item and the fourth measurement item of a target sample group in the sample to be measured. The sample dispensing mechanism is controlled to inject samples corresponding to the third measurement items into corresponding third measurement cups in sequence, and then incubation is started. The cup conveying mechanism is controlled to transfer second timeout measurement cups in the third measurement cups that exceed an incubation time length to the test area for measurement, so as to obtain third measurement results. After the second timeout measurement cups are transferred to the test area, the cup conveying mechanism is controlled to load fourth measurement cups of the fourth measurement item to positions of the second timeout measurement cups in the pre-warming area, so as to online the fourth measurement item to the sample analyzer, and obtain fourth measurement results. The sample analyzer further includes an output device configured to output the third measurement results and the fourth measurement results as the target measurement results.

13. The sample analyzer of any one of claims 9 to 12, wherein, The number of samples is determined by the processing capacity of the sample analyzer, and the processing capacity of the sample analyzer is used to indicate the number of samples processed by the sample analyzer within a sample incubation time length.

14. The sample analyzer of claim 13, wherein, The processor is further configured to acquire the processing capacity of the sample analyzer.

15. The sample analyzer of claim 13, wherein, The processor is specifically configured to acquire a minimum incubation time length of each measurement item in the sample to be measured, and an injection time length of a single sample and a sample buffer of the single sample. The processing capacity of the sample analyzer is obtained according to the minimum incubation time length and the injection time length.

16. The sample analyzer of any one of claims 9 to 12, wherein, The processor is further configured to acquire an item sequence of each measurement item in the sample to be measured, the item sequence being used to indicate an online sequence of each measurement item in the sample group. 17.A computer readable storage medium, the computer readable storage medium storing computer instructions for performing the method of any one of claims 1 to 8. 18.A computer program product comprising instructions which, when executed on a computer, cause the computer to carry out the method of any one of claims 1 to 8.

Citation Information

Patent Citations

  • Specimen transportation system and method for controlling same

    CN103339511A

  • Autoanalyzer, carry-over checking method, carry-over checking program, and carry-over checking kit

    JP2007205763A

  • Blood analyzer and control method therefor

    WO2019033312A1