A traditional Chinese medicine composition for preventing and treating skin chapped skin and a traditional Chinese medicine product thereof

Abstract

The present invention relates to the technical field of traditional Chinese medicine, and in particular to a traditional Chinese medicine composition for preventing and treating chapped skin and its traditional Chinese medicine products, comprising indocalamus, sanguisorba officinalis, rhubarb, catechu, sophora flavescens, stemona radix and safflower. Indocalamus is the main drug, and its main effects are clearing away heat and cooling blood, and it also has astringent and hemostatic effects. Sanguisorba officinalis, rhubarb and catechu are assistant drugs, which play a synergistic role in the combination and jointly enhance the blood circulation and repair function of the skin. Sophora flavescens, stemona radix and safflower are adjuvant drugs, which can enhance the heat-clearing, damp-drying, blood-activating and analgesic effects of indocalamus in the combination. The compatibility effects between the various drug prescriptions mainly revolve around dispersing blood stasis and activating blood circulation, clearing heat and cooling blood, relieving pain, reducing inflammation and astringent and hemostatic effects. The various components work together to enhance the therapeutic effects of the drugs, thereby achieving the purpose of preventing and treating chapped skin.

Description

Technical Field

[0001] The present invention relates to the technical field of traditional Chinese medicines, and in particular to a traditional Chinese medicine composition for preventing and treating skin chapped skin and a traditional Chinese medicine product thereof. Background Art

[0002] Because winter is cold and dry, sweat secretion is less, and the skin surface lacks sebum to moisturize. Due to long-term exercise or friction, contact with alkaline detergents or solutions, etc., cracks of varying lengths and depths can easily appear on the palms, backs and curved sides of fingers, heels, etc. Cracks that are too deep will bleed and cause severe pain.

[0003] Cracks, also known as chapped skin, are a common clinical skin disease symptom in winter, accompanied by itching and pain. The incidence is higher among construction workers, agricultural practitioners, fishery practitioners and the elderly, causing great troubles and physical torture to this group's work and life.

[0004] There are many medicines for chapped skin on the market, but most of them are treated by applying Vaseline directly to the skin surface for protection, or taking oral vitamins. Ointments with Chinese medicine as components and combining protection and treatment are extremely rare. Combining the concept of integrated medical care in traditional Chinese medicine, they can deeply improve the skin surface environment, promote blood circulation on the body surface, repair damaged skin, and protect fragile skin from further damage.

[0005] The patients targeted by the present invention are mainly concentrated in Nayong County and Qixingguan District of Guizhou Province. The general characteristics are that from the end of November to April of the following year, the northwestern part of Guizhou Province is often cloudy and humid, and the sun is rarely seen throughout the winter. Agricultural workers work outside all year round, and after returning home after dark, they mainly use coal stoves for heating. In addition, the area is a high-sulfur mining area, which leads to cold and wet hands and feet at any time. When they are baked next to the coal stove, their hands and feet are easily chapped and the wounds are extremely difficult to heal.

[0006] Based on the above situation, it is of great practical significance to develop a skin care product for external use that can prevent and treat chapped skin based on the medical concept of traditional Chinese medicine, with Chinese medicine components as the core, and has the functions of killing insects and relieving itching, promoting blood circulation on the body surface, and restoring damaged skin. Summary of the Invention

[0007] The purpose of the present invention is to provide a traditional Chinese medicine composition and traditional Chinese medicine products for preventing and treating chapped skin, which are non-irritating, have no toxic side effects, and have good therapeutic effects on treating chapped hands and feet in winter and healing skin wounds.

[0008] In order to achieve the above technical objectives and the above technical effects, the present invention is implemented through the following technical solutions:

[0009] A traditional Chinese medicine composition for preventing and treating skin chapped skin comprises indocalamus, dragon's blood, rhubarb, catechu, sophora flavescens, stemona and safflower.

[0010] Furthermore, the weight ratio of the raw materials of the traditional Chinese medicine composition is: 7-14 parts of Indocalamus, 8-11 parts of Sanguisorba officinalis, 3-5 parts of Rhubarb, 7-9 parts of Catechu, 4-7 parts of Sophora flavescens, 4-7 parts of Stemona, and 3-5 parts of Carthamus tinctorius.

[0011] Furthermore, the weight ratio of the raw materials of the traditional Chinese medicine composition is: 12 parts of Indocalamus, 9 parts of Sanguisorba officinalis, 4 parts of Rhubarb, 7 parts of Catechu, 5 parts of Sophora flavescens, 6 parts of Stemona bulbs, and 4 parts of Carthamus tinctorius.

[0012] On the other hand, the present invention provides a traditional Chinese medicine product for preventing and treating skin chapped skin, wherein the traditional Chinese medicine product is an external-use medicament prepared from the above-mentioned traditional Chinese medicine composition.

[0013] Furthermore, the topical medicaments include but are not limited to ointments, oils, emulsions, creams and sprays.

[0014] Furthermore, the preparation of the ointment comprises the following steps:

[0015] S1: After fully mixing the various Chinese medicines in the Chinese medicine composition according to proportion, the mixture is placed in a vacuum drying oven for drying;

[0016] S2: Grind the dried Chinese medicinal components with a grinder, pass them through a 40-mesh sieve, and sieve the remaining components. Continue grinding and sieving until all components are sieved;

[0017] S3: placing the crushed and sieved Chinese medicinal components in a ceramic or iron can, adding 100 parts of sesame oil, stirring evenly, and sealing the can with a lid for soaking. Stirring once every 24 hours to ensure that the sesame oil always soaks the Chinese medicinal components. The soaking time is 5 days, until the sesame oil is completely soaked;

[0018] S4: Pour the soaked Chinese medicinal components and sesame oil into an iron pot to boil the medicinal oil. Use a liquefied petroleum liquefaction furnace as the boiling stove. Heat the pot over high heat until the oil temperature rises and the medicinal components begin to change color. Then, reduce the heat and continue boiling until most of the medicinal component particles are precipitated and coked. Stop boiling when the particles break when twisted by hand. The boiling time is 2-3 hours.

[0019] S5: Cool the boiled medicinal oil, filter out the medicinal residue with gauze, and reheat the remaining medicinal oil in an iron pot. Boil it over a low heat to concentrate the medicinal oil until the medicinal oil does not disperse when dropped into water. The concentration time is 0-1 hour.

[0020] S6: Set the concentrated medicinal oil aside to cool to 70-80°C for later use, melt the vaseline in an iron pot again at 70-80°C, and after the vaseline is completely melted, pour the medicinal oil in equal volume proportions and stir the mixture thoroughly;

[0021] S7: Pour the mixed medicinal oil into the detoxified wide-mouth bottle, cool it to room temperature and store it for later use, thereby obtaining a paste Chinese medicine product.

[0022] Xuejie: ​​Nature and flavor: sweet, salty, neutral; enters the Heart and Liver meridians; Indications: Disperses blood stasis, relieves pain, stops bleeding and promotes tissue regeneration. Treats bruises, internal injuries, pain from blood stasis, persistent bleeding from external injuries, scrofula, and persistent ulcers. Tang Materia Medica: Treats pathogenic qi in the five internal organs, leucorrhea, relieves pain, dissipates blood clots, and promotes tissue regeneration from metal wounds.

[0023] Indocalamus: Nature and flavor: slightly cold, bitter, sweet, astringent; enters the Lung, Liver, and Stomach meridians; Indications: Treats hemoptysis and vomiting blood, hemoptysis caused by tuberculosis, bleeding caused by ulcers, stops lung bleeding, treats silicosis, has astringent and hemostatic properties, reduces swelling and promotes tissue regeneration, and is used for internal and external bleeding, as well as carbuncles, burns, chapped hands and feet, and anal fissures. Ben Jing: Treats carbuncles, malignant sores, gangrene, damage to the yin and dead muscles, evil spirits in the stomach, and lingering wind-induced prickly heat.

[0024] Rhubarb: Nature and flavor: bitter, cold; enters the Stomach, Large Intestine, and Liver meridians; Indications: Purging heat and toxins, dissolving stagnation, and promoting blood circulation. Treats constipation due to excess heat, delirium, food stagnation, initial dysentery, tenesmus, stasis and amenorrhea, accumulation of masses, epidemic febrile diseases, sudden onset of red and painful eyes, hematemesis, epistaxis, jaundice, edema, stranguria, carbuncle, boils, and burns. "Ben Jing": Dissipates blood stasis, blood stasis, cold and heat, dissolves mass accumulation, treats retained fluid and food, cleanses the intestines, removes the old and brings in the new, promotes the flow of water and food, regulates digestion, and harmonizes the five internal organs.

[0025] Catechu: Bitter in nature and flavor; cool; non-toxic; enters the Heart and Lung meridians; Indications: Clears heat and resolves phlegm, aids digestion, promotes blood circulation and heals wounds, stops bleeding and promotes tissue regeneration, and heals sores. Treats coughs caused by phlegm heat, thirst, hematemesis, epistaxis, hematuria, bloody dysentery, metrorrhagia, indigestion in children, dental caries, mouth sores, throat paralysis, and damp sores. "Compendium of Materia Medica": Reduces internal heat and promotes fluid production, clears phlegm and coughs, treats mouth sores, throat paralysis, fever, stops thirst, hematemesis, epistaxis, bloody stool, hematuria, damp-heat dysentery, metrorrhagia, prolonged menstruation, infantile malnutrition, mouth sores, heat sores, damp-heat ulcers, hemorrhage, and hemorrhage in women; heals uterine bleeding, prolonged menstruation, infantile malnutrition, mouth sores, heat sores, damp-heat ulcers, hemorrhage, and hemorrhoids; heals and grows flesh; and kills insects.

[0026] Sophora flavescens: Bitter in nature; cold in nature. It is used in the Liver, Kidney, Large Intestine, and Stomach meridians. Indications: Clears heat, dries dampness, and kills parasites. It treats toxic heat-induced bloody dysentery, intestinal bleeding, jaundice, leucorrhea, pneumonia in children, malnutrition, acute tonsillitis, fistula, rectal prolapse, itchy skin, scabies, ulcers, itchy genital sores, scrofula, and burns. It is also used externally to treat trichomonas vaginitis. According to Materia Medica, it treats toxic heat-induced wind, irritable skin and muscles, ulcers, red scabies, and eyebrow loss. It also relieves severe fever and drowsiness, treats cold pain in the abdomen, abdominal pain from the stomach, relieves stuffiness, and treats abdominal congestion.

[0027] Stemona: Nature and flavor: sweet and bitter, slightly warm; enters the Lung meridian; Indications: warms and moistens the lungs, relieves coughs, and kills parasites. Treats coughs caused by wind and cold, whooping cough, tuberculosis, cough and asthma in the elderly, ascariasis, pinworms, skin scabies, and eczema. "Compendium of Materia Medica Supplement": Roasted and soaked in wine, drink on an empty stomach to treat insect bites and scabies.

[0028] Safflower: Nature and flavor: Pungent, warm; enters the Heart and Liver meridians; Indications: Promotes blood circulation and menstruation, removes blood stasis and relieves pain. Treats amenorrhea, abdominal masses, dystocia, stillbirth, postpartum lochia retention, blood stasis and pain, carbuncles, and injuries from falls. Compendium of Materia Medica: Promotes blood circulation, moistens dryness, relieves pain, disperses swelling, and promotes menstruation.

[0029] Beneficial effects of the present invention:

[0030] The present invention provides a Chinese medicine composition and Chinese medicine product for preventing and treating chapped skin, which has the effects of insecticide, sterilization, itching relief, blood circulation promotion, and sore astringency. The raw materials are a combination of all Chinese medicines, which has the advantages of low irritation, no toxic side effects, high cure rate, and few medication contraindications. The present invention is matched strictly in accordance with the compatibility of traditional Chinese medicine, wherein Indocalamus ovata is used as the monarch drug for astringency, Sanguisorba officinalis, Rhubarb, and Catechu are used as the ministerial drugs for enhancing the blood circulation and repair function of the skin, Sophora flavescens, Stemona tuber, and Carthamus tinctorius are used as adjuvants for enhancing the heat-clearing, dampness-drying, blood circulation promotion, and analgesic effects of Indocalamus ovata, while Sanguisorba officinalis is used for dispersing blood stasis, relieving pain, stopping bleeding, and promoting tissue regeneration, and Rhubarb has the effects of purging heat and toxins, breaking up stagnation, and promoting the circulation of blood stasis.

[0031] Indocalamus is the main medicine, and its main effects are clearing away heat and cooling blood, and it also has the effect of astringing and stopping bleeding.

[0032] Dragon's blood, rhubarb and catechu are assistant medicines, which play a synergistic role in the combination to enhance the blood circulation and repair function of the skin.

[0033] Sophora flavescens, Stemona radix and Carthamus tinctorius are adjuvants, which can enhance the heat-clearing, dampness-drying, blood-activating and analgesic effects of Indocalamus chinensis in combination.

[0034] Xuejie has the effects of dispersing blood stasis, relieving pain, stopping bleeding and promoting tissue regeneration, while rhubarb has the effects of purging heat and toxins, breaking up stagnation and promoting blood circulation. The combination of the two can work synergistically, enhancing the effects of dispersing blood stasis and activating blood circulation, improving blood circulation in the skin and promoting the repair of cracks.

[0035] Indocalamus has the effects of clearing heat, cooling blood, astringing and stopping bleeding, while Rhubarb has the effects of purging heat and toxins, breaking up stagnation, and promoting the flow of blood stasis. The combination of the two can synergistically clear heat and cool blood, and has a good effect on problems such as damp-heat on the skin and blood stasis; Sophora flavescens has the effects of clearing heat, drying dampness, and killing insects. When combined with Indocalamus, it can have a synergistic anti-inflammatory effect, and has an auxiliary therapeutic effect on skin inflammation and itching symptoms; Safflower has the effects of promoting blood circulation, dredge menstruation, removing blood stasis and relieving pain, and when combined with Indocalamus, it can have a synergistic analgesic effect, and can improve the pain caused by skin blood stasis. The combination of Xuejie and Rhubarb with Indocalamus can work together to disperse blood stasis, break up stagnation, accelerate blood circulation, and promote skin repair.

[0036] In summary, the compatibility of the various medicinal components in this prescription mainly focuses on dispersing blood stasis and promoting blood circulation, clearing heat and cooling blood, relieving pain, reducing inflammation, and astringing and stopping bleeding. They can synergize with each other, enhancing the therapeutic effects of the drugs, thereby achieving the purpose of preventing and treating skin cracks.

[0037] Of course, any product implementing the present invention does not necessarily need to achieve all of the advantages described above at the same time. DETAILED DESCRIPTION

[0038] The following is a clear and complete description of the technical solutions in the embodiments of the present invention. Obviously, the embodiments described are only some embodiments of the present invention, not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making any creative efforts are within the scope of protection of the present invention. Example 1

[0039] The present embodiment provides a traditional Chinese medicine composition for preventing and treating chapped skin, comprising indocalamus, dragon's blood, rhubarb, catechu, sophora flavescens, stemona and safflower.

[0040] In this embodiment, the weight ratio of the raw materials of the Chinese medicine composition is: 7-14 parts of Indocalamus, 8-11 parts of Sanguisorba officinalis, 3-5 parts of Rhubarb, 7-9 parts of Catechu, 4-7 parts of Sophora flavescens, 4-7 parts of Stemona, and 3-5 parts of Carthamus tinctorius.

[0041] On the other hand, the present invention provides a traditional Chinese medicine product for preventing and treating skin chapped skin, wherein the traditional Chinese medicine product is an external-use medicament prepared from the above-mentioned traditional Chinese medicine composition.

[0042] In this embodiment, the topical medicaments include but are not limited to ointments, oils, emulsions, creams, and sprays.

[0043] In this embodiment, the preparation of the ointment includes the following steps:

[0044] S1: After fully mixing the various Chinese medicines in the Chinese medicine composition according to proportion, the mixture is placed in a vacuum drying oven for drying;

[0045] S2: Grind the dried Chinese medicinal components with a grinder, pass them through a 40-mesh sieve, and sieve the remaining components. Continue grinding and sieving until all components are sieved;

[0046] S3: placing the crushed and sieved Chinese medicinal components in a ceramic or iron can, adding 100 parts of sesame oil, stirring evenly, and sealing the can with a lid for soaking. Stirring once every 24 hours to ensure that the sesame oil always soaks the Chinese medicinal components. The soaking time is 5 days, until the sesame oil is completely soaked;

[0047] S4: Pour the soaked Chinese medicinal components and sesame oil into an iron pot to boil the medicinal oil. Use a liquefied petroleum liquefaction furnace as the boiling stove. Heat the pot over high heat until the oil temperature rises and the medicinal components begin to change color. Then, reduce the heat and continue boiling until most of the medicinal component particles are precipitated and coked. Stop boiling when the particles break when twisted by hand. The boiling time is 2-3 hours.

[0048] S5: Cool the boiled medicinal oil, filter out the medicinal residue with gauze, and reheat the remaining medicinal oil in an iron pot. Boil it over a low heat to concentrate the medicinal oil until the medicinal oil does not disperse when dropped into water. The concentration time is 0-1 hour.

[0049] S6: Set the concentrated medicinal oil aside to cool to 70-80°C for later use, melt the vaseline in an iron pot again at 70-80°C, and after the vaseline is completely melted, pour the medicinal oil in equal volume proportions and stir the mixture thoroughly;

[0050] S7: Pour the mixed medicinal oil into the detoxified wide-mouth bottle, cool it to room temperature and store it for later use, thereby obtaining a paste Chinese medicine product. Example 2

[0051] The present embodiment provides a traditional Chinese medicine composition for preventing and treating chapped skin, comprising indocalamus, dragon's blood, rhubarb, catechu, sophora flavescens, stemona and safflower.

[0052] In this embodiment, the weight ratio of the raw materials of the Chinese medicine composition is: 12 parts of Indocalamus, 9 parts of Sanguisorba officinalis, 4 parts of Rhubarb, 7 parts of Catechu, 5 parts of Sophora flavescens, 6 parts of Stemona bulbs, and 4 parts of Carthamus tinctorius. Example 3

[0053] The present embodiment provides a traditional Chinese medicine composition for preventing and treating chapped skin, comprising indocalamus, dragon's blood, rhubarb, catechu, sophora flavescens, stemona and safflower.

[0054] In this embodiment, the weight ratio of the raw materials of the Chinese medicine composition is: 11 parts of Indocalamus, 8 parts of Sanguisorba officinalis, 3 parts of Rhubarb, 6 parts of Catechu, 4 parts of Sophora flavescens, 5 parts of Stemona bulbs, and 3 parts of Carthamus tinctorius. Example 4

[0055] The present embodiment provides a traditional Chinese medicine composition for preventing and treating chapped skin, comprising indocalamus, dragon's blood, rhubarb, catechu, sophora flavescens, stemona and safflower.

[0056] In this embodiment, the weight ratio of the raw materials of the Chinese medicine composition is: 13 parts of Indocalamus, 10 parts of Sanguisorba officinalis, 5 parts of Rhubarb, 8 parts of Catechu, 6 parts of Sophora flavescens, 7 parts of Stemona japonica, and 5 parts of Carthamus tinctorius. Example 5

[0057] Clinical trials:

[0058] A total of 61 patients with chapped hands and feet were selected, including 57 patients with chapped hands, 11 patients with chapped heels, and 10 patients with chapped hands and feet. The patients were mainly concentrated in Nayong County and Qixingguan District in Guizhou Province. The overall characteristics were that from the end of November to April of the following year, the weather in the northwest of Guizhou Province was mostly cloudy and humid, and the sun was rarely seen throughout the winter. Agricultural workers worked outside all year round, and after returning home after dark, they mainly used coal stoves for heating. In addition, the area is a high-sulfur mining area, which leads to cold and wet hands and feet at any time. When they are baked next to a coal stove, their hands and feet are easily chapped, and the wounds are extremely difficult to heal.

[0059] The Chinese medicine composition for preventing and treating chapped skin obtained in Example 2 was administered to the patient 4 times a day, namely in the morning, noon, evening and before bedtime. One course of treatment was 7 consecutive days, and the drug was discontinued after 3 courses of treatment.

[0060] Criteria for judging efficacy:

[0061] Cure: After 2-3 courses of treatment, the skin symptoms disappear, the symptoms return to normal, and the surface returns to normal luster;

[0062] Significant effect: After 2-3 courses of treatment, skin symptoms are alleviated and cracks and chappings slowly heal;

[0063] Ineffective: After 2-3 courses of medication, the skin symptoms remain unchanged or worsen;

[0064] Treatment results:

[0065] After 2-3 courses of treatment, 49 patients with chapped hands were cured, 7 had significant effects, 5 had no effect, and the total effective rate of chapped hands was 91.8%; 10 patients with chapped feet were cured, 0 had significant effects, 1 had no effect, and the total effective rate was 90.9%; 7 patients with chapped hands and feet were cured, 1 had significant effects, 2 had no effect, and the total effective rate was 80%.

[0066] The preferred embodiments of the present invention disclosed above are intended only to help illustrate the present invention. These preferred embodiments do not exhaustively describe all details, nor do they limit the present invention to the specific embodiments described. Obviously, many modifications and variations are possible based on the content of this specification. These embodiments are selected and described in detail in this specification to better explain the principles and practical applications of the present invention, thereby enabling those skilled in the art to better understand and utilize the present invention. The present invention is limited only by the claims and their full scope and equivalents.

Claims

1. A Chinese medicinal composition for external use for preventing and treating chapped skin, characterized in that: The traditional Chinese medicine composition consists of indolan 7-14 parts, dragon's blood, rhubarb, catechu, sophora flavescens, stemona radix and safflower; the weight ratio of the raw materials of the traditional Chinese medicine composition is: indolan 7-14 parts, dragon's blood 8-11 parts, rhubarb 3-5 parts, catechu 7-9 parts, sophora flavescens 4-7 parts, stemona radix 4-7 parts and safflower 3-5 parts.

2. The Chinese medicine composition according to claim 1, wherein: The weight ratio of the raw materials of the traditional Chinese medicine composition is: 12 parts of indocalamus, 9 parts of dragon's blood, 4 parts of rhubarb, 7 parts of catechu, 5 parts of sophora flavescens, 6 parts of stemona, and 4 parts of safflower.

3. A Chinese medicine product for preventing and treating skin chapped skin, characterized in that: The Chinese medicine product is an external-use medicament prepared from the Chinese medicine composition according to claim 1 or 2.

4. The Chinese medicine product according to claim 3, characterized in that: The topical medicaments include, but are not limited to, ointments, oils, emulsions, creams and sprays.

5. The Chinese medicine product according to claim 4, characterized in that: The preparation of the ointment comprises the following steps: S1: After fully mixing the various Chinese medicines in the Chinese medicine composition according to proportion, the mixture is placed in a vacuum drying oven for drying; S2: Grind the dried Chinese medicinal components with a grinder, pass them through a 40-mesh sieve, and sieve the remaining components. Continue grinding and sieving until all components are sieved; S3: placing the crushed and sieved Chinese medicinal components in a ceramic or iron can, adding 100 parts of sesame oil, stirring evenly, and sealing the can with a lid for soaking. Stirring once every 24 hours to ensure that the sesame oil always soaks the Chinese medicinal components. The soaking time is 5 days, until the sesame oil is completely soaked; S4: Boil the soaked Chinese medicinal components and sesame oil in a medicinal oil. After the medicinal components begin to change color, reduce the heat from high to low and continue boiling until most of the medicinal component particles are precipitated and coked. Stop boiling when the particles break when twisted by hand. The boiling time is 2-3 hours. S5: Cool the boiled medicinal oil, filter out the medicinal residue with gauze, and reheat the remaining medicinal oil in an iron pot. Boil it over a low heat to concentrate the medicinal oil until the medicinal oil does not disperse when dropped into water. The concentration time is 0-1 hour. S6: Set the concentrated medicinal oil aside to cool to 70-80°C for later use, melt the vaseline in an iron pot again at 70-80°C, and after the vaseline is completely melted, pour the medicinal oil in equal volume proportions and stir the mixture thoroughly; S7: Pour the vaseline and medicated oil mixture obtained in step S6 into the decontaminated wide-mouth bottle, cool it to room temperature and store it for later use, thereby obtaining a paste Chinese medicine product.