A traditional Chinese medicine composition for treating low back pain caused by movement system diseases and application thereof

Abstract

The application discloses a traditional Chinese medicine composition for treating lumbar pain caused by diseases of the motor system and application thereof, and relates to the technical field of traditional Chinese medicines.The traditional Chinese medicine composition comprises yam, dogwood, prepared rehmannia, cassia twig, radix angelicae pubescentis, raw eucommia, rhizoma anemarrhenae, drynaria, frankincense, myrrh, chuanxiong, angelica sinensis, cyperus rotundus, achyranthes bidentata, amomum villosum, tangerine peel, gentiana, polygala, and licorice.The traditional Chinese medicine composition has the effects of tonifying liver and kidney, strengthening bones and muscles, promoting blood circulation to remove meridian obstruction, and relieving swelling and pain, and can be used for treating lumbar pain caused by various diseases of the motor system, such as lumbar hyperosteogeny, intervertebral disc herniation, lumbar vertebra hypertrophy, spinal stenosis, lumbar fracture, spinal canal tumor, acute and chronic trauma or strain of the lumbar region, lumbar muscle strain, and ankylosing spondylitis, and has outstanding curative effects on acute and chronic lumbar pain.

Description

Technical Field

[0001] This invention belongs to the field of traditional Chinese medicine technology, specifically, it relates to a traditional Chinese medicine composition for treating lower back pain caused by musculoskeletal diseases and its application. Background Technology

[0002] Lower back pain is a common clinical symptom, primarily characterized by pain on one or both sides of the lower back, often radiating to the legs, and frequently accompanied by symptoms of external or internal injury. Many factors can cause lower back pain. Besides diseases of the musculoskeletal system and injuries, diseases of other organs can also cause it. These include urinary tract infections or stones, glomerulonephritis, certain gynecological diseases, pregnancy, lumbar radiculitis, and certain abdominal diseases. Commonly seen causes include lumbar osteophytes, herniated discs, lumbar hypertrophy, spinal stenosis, lumbar fractures, spinal tumors, acute or chronic lumbar injuries or strains, lumbar muscle strain, and ankylosing spondylitis.

[0003] The Department of Traditional Chinese Medicine sees an average of over 50,000 outpatients annually, with about 8% of them experiencing lower back pain due to musculoskeletal disorders. In the past 10 years, the total number of patients has reached over 40,000. Traditional Chinese medicine theory emphasizes treating the symptoms, so it is both necessary and meaningful to develop a Chinese herbal formula that can greatly improve the efficiency and effectiveness of treatment for lower back pain caused by musculoskeletal disorders.

[0004] In view of this, the present invention is proposed. Summary of the Invention

[0005] The technical problem to be solved by the present invention is to overcome the shortcomings of the prior art and provide a traditional Chinese medicine composition for treating low back pain caused by musculoskeletal diseases and its application, which can effectively treat low back pain caused by musculoskeletal diseases.

[0006] To solve the above-mentioned technical problems, the basic concept of the technical solution adopted by the present invention is as follows:

[0007] This invention provides a traditional Chinese medicine composition, comprising the following components by weight: 10-15 parts of Dioscorea opposita, 10-15 parts of Cornus officinalis, 10-15 parts of Rehmannia glutinosa (processed), 10-15 parts of Cinnamomum cassia, 5-10 parts of Angelica pubescens, 15-20 parts of Eucommia ulmoides (raw), 15-20 parts of Dipsacus asper, 15-20 parts of Drynaria fortunei, 10-15 parts of Boswellia carterii, 10-15 parts of Commiphora myrrha, 10-15 parts of Ligusticum chuanxiong, 15-20 parts of Angelica sinensis, 10-15 parts of Cyperus rotundus, 15-20 parts of Achyranthes bidentata, 3-6 parts of Amomum villosum, 5-10 parts of Citrus reticulata peel, 10-15 parts of Gentiana macrophylla, 20-30 parts of Polygala tenuifolia, and 10-15 parts of Glycyrrhiza uralensis.

[0008] Further, by weight, the traditional Chinese medicine composition comprises the following components: 15 parts of Dioscorea opposita, 15 parts of Cornus officinalis, 15 parts of Rehmannia glutinosa (processed), 15 parts of Cinnamomum cassia, 10 parts of Angelica pubescens, 20 parts of Eucommia ulmoides (raw), 20 parts of Dipsacus asper, 20 parts of Drynaria fortunei, 15 parts of Boswellia carterii, 15 parts of Commiphora myrrha, 15 parts of Ligusticum chuanxiong, 20 parts of Angelica sinensis, 15 parts of Cyperus rotundus, 20 parts of Achyranthes bidentata, 6 parts of Amomum villosum, 10 parts of Citrus reticulata peel, 15 parts of Gentiana macrophylla, 30 parts of Polygala tenuifolia, and 15 parts of Glycyrrhiza uralensis.

[0009] The present invention also provides the application of the above-mentioned traditional Chinese medicine composition in the preparation of a medicine for treating low back pain caused by musculoskeletal diseases.

[0010] The present invention also provides a medicine for treating lower back pain caused by musculoskeletal disorders, the raw materials of which include the above-mentioned traditional Chinese medicine composition.

[0011] Furthermore, the drug also includes pharmaceutically acceptable excipients.

[0012] Furthermore, the excipients include excipients.

[0013] Furthermore, the excipient is honey.

[0014] Furthermore, the dosage form of the drug is a decoction, tablet, pill, granule, or capsule.

[0015] Regardless of the cause of lower back pain due to any musculoskeletal disorder, the primary symptom is pain, which in turn affects motor function. In Traditional Chinese Medicine (TCM) theory, relieving pain is the primary task. Pain is considered to stem from either "obstruction" or "lack of nourishment." Clinical experience shows that acute injuries primarily present with "obstruction," while lower back pain caused by degenerative changes involves both. Therefore, this invention develops an oral TCM formula based on the two treatment principles of "free flow prevents pain" and "nourished nourishment prevents pain."

[0016] When there is free flow, there is no pain: Traditional Chinese medicine believes that the main reasons for "obstruction" are blood stasis and cold stagnation. Therefore, "free flow" means dispersing blood stasis and reducing swelling, warming the meridians and dispelling cold, and promoting qi and blood circulation.

[0017] "Nourishing the kidneys prevents pain": Traditional Chinese medicine believes that the waist is the residence of the kidneys, and the kidneys govern bones and produce marrow. The liver and kidneys share the same origin. Therefore, most patients with chronic lower back pain suffer from liver and kidney deficiency. Conversely, prolonged illness also depletes the liver and kidneys, leading to further deficiency. Therefore, "nourishing the kidneys" is a way to nourish the liver and kidneys, strengthen muscles and bones, and has a positive therapeutic effect on both acute and chronic lower back pain patients.

[0018] Based on the above TCM theories, the self-developed oral Chinese medicine formula of this invention consists of: Chinese yam, Cornus officinalis, Rehmannia glutinosa, Cinnamomum cassia, Angelica pubescens, Eucommia ulmoides, Dipsacus asper, Drynaria fortunei, Boswellia carterii, Commiphora myrrha, Ligusticum chuanxiong, Angelica sinensis, Cyperus rotundus, Achyranthes bidentata, Amomum villosum, Citrus reticulata peel, Gentiana macrophylla, Polygala tenuifolia, and Glycyrrhiza uralensis.

[0019] (1) Single drug effect

[0020] Yam: Strengthens the spleen, nourishes the lungs, tonifies the kidneys, and benefits essence.

[0021] Cornus officinalis: Nourishes the liver and kidneys, astringes and consolidates the body.

[0022] Rehmannia glutinosa (processed): Nourishes Yin and blood, benefits essence and replenishes marrow.

[0023] Cinnamon twig: promotes sweating and relieves muscle tension, warms and unblocks the meridians, and assists yang and qi transformation.

[0024] Angelica pubescens: dispels wind and dampness, relieves pain and numbness.

[0025] Raw Eucommia: Tonifies the liver and kidneys, strengthens muscles and bones, and calms the fetus.

[0026] Dipsacus: Nourishes the liver and kidneys, strengthens tendons and bones, heals injuries and fractures, stops bleeding and calms the fetus.

[0027] Drynaria fortunei: It tonifies the kidneys, strengthens bones, heals injuries, and relieves pain.

[0028] Frankincense: Promotes blood circulation, relieves pain, reduces swelling, and promotes tissue regeneration.

[0029] Myrrh: promotes blood circulation, relieves pain, reduces swelling and promotes tissue regeneration.

[0030] Chuanxiong (Ligusticum striatum): invigorates blood circulation, promotes qi flow, dispels wind, and relieves pain.

[0031] Angelica sinensis: Nourishes blood and promotes blood circulation, regulates menstruation and relieves pain, moistens the intestines and promotes bowel movement.

[0032] Cyperus rotundus: Soothes the liver and relieves depression, regulates qi and relieves chest tightness, regulates menstruation and relieves pain.

[0033] Achyranthes bidentata: removes blood stasis and unblocks meridians, tonifies the liver and kidneys, strengthens tendons and bones, promotes urination and relieves strangury, and guides blood downward.

[0034] Gentiana macrophylla: dispels wind and dampness, clears damp heat, relieves numbness and pain, and reduces deficiency heat.

[0035] Dried tangerine peel: regulates qi and strengthens the spleen, dries dampness and resolves phlegm.

[0036] Polygala tenuifolia: calms the mind and improves intelligence, eliminates phlegm and clears the orifices, and reduces carbuncles and swellings.

[0037] Amomum villosum: It can dispel dampness, stimulate appetite, warm the spleen, stop diarrhea, regulate qi, and calm the fetus.

[0038] Licorice: Tonifies the spleen and replenishes qi, clears heat and detoxifies, eliminates phlegm and relieves cough, relieves spasms and pain, and harmonizes the effects of other herbs.

[0039] (2) Drug composition grouping and the range of group ratios:

[0040] Kidney-tonifying, spleen-strengthening, and pain-relieving group: Chinese yam, Cornus officinalis, and Rehmannia glutinosa.

[0041] The Qi-regulating, blood-activating, and pain-relieving group consists of Angelica sinensis, Ligusticum chuanxiong, and Cyperus rotundus.

[0042] The group for dispersing blood stasis, reducing swelling, and relieving pain includes frankincense, myrrh, gentian root, and polygala root.

[0043] Warming the meridians, dispelling wind, and relieving pain group: Cinnamon twig, Angelica pubes

[0044] Kidney-tonifying, tendon-strengthening, and injury-healing group: raw Eucommia ulmoides, Dipsacus asper, Drynaria fortunei, and Achyranthes bidentata.

[0045] The formula for regulating the spleen and stomach and preventing greasy foods includes: Amomum villosum, dried tangerine peel, and licorice.

[0046] In the oral Chinese medicine formula of this invention, the principal herbs are frankincense, myrrh, chuanxiong, angelica, and cyperus. Among them, frankincense and myrrh invigorate blood, reduce swelling, and relieve pain; chuanxiong, angelica, and cyperus nourish blood, invigorate blood circulation, promote qi circulation, remove blood stasis, and relieve pain. Together, they serve as the principal herbs to clear blockages and relieve pain. Dioscorea, cornus, and prepared rehmannia nourish the liver and kidneys; raw eucommia, dipsacus, drynaria, and achyranthes benefit the kidneys, strengthen tendons, and heal injuries. As assistant herbs, they assist the principal herbs in nourishing the body and relieving pain. Cinnamon twig warms the meridians and dispels cold; angelica pubescens dispels wind and dampness. Together, they serve as adjuvant herbs to assist the principal and assistant herbs in exerting a more comprehensive effect of invigorating blood, reducing swelling, warming the meridians, dispelling cold, benefiting the kidneys, strengthening tendons, and relieving pain. Amomum villosum and tangerine peel regulate qi and harmonize the stomach, preventing the cloying nature of tonifying herbs from hindering the stomach and the damage to the spleen and stomach caused by digestive and blood-stasis-removing herbs. Licorice harmonizes all the herbs and serves as the guiding herb.

[0047] By adopting the above technical solution, the present invention has the following beneficial effects compared with the prior art.

[0048] The self-developed Chinese herbal medicine formula provided by this invention has the effects of tonifying the liver and kidneys, strengthening muscles and bones and relieving pain (when the body is healthy, there is no pain), and promoting blood circulation and removing blood stasis, reducing swelling and relieving pain (when the flow is smooth, there is no pain). It can be used to treat acute and chronic low back pain caused by diseases of the musculoskeletal system, such as lumbar osteophyte, intervertebral disc herniation, lumbar hypertrophy, spinal stenosis, lumbar fracture, spinal tumor, acute and chronic lumbar trauma or strain, lumbar muscle strain, ankylosing spondylitis and other low back pain.

[0049] The specific embodiments of the present invention will be described in further detail below. Detailed Implementation

[0050] To make the objectives, technical solutions, and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments will be clearly and completely described below. The following embodiments are used to illustrate the present invention, but are not intended to limit the scope of the present invention.

[0051] Example 1

[0052] (1) According to the proportions shown in Example 1 in Table 1, mix and decoct the various Chinese herbal ingredients. Use a clay pot as a container, add an appropriate amount of water, and decoct twice, each time for 30 minutes. Mix the resulting Chinese herbal decoctions together. The weight ratio of the Chinese herbal mixture to water is 1:1, both times. (1:1-1.5 can achieve the same effect. The ratio of the Chinese herbal mixture to water has no effect on the efficacy, but the minimum amount of water is required to ensure that the Chinese herbal mixture can keep boiling during the 30-minute decoction process. The amount of water can be slightly more, but not less. It is necessary to take all the decoctions as required. For patients with other diseases that are not suitable for drinking too much water at one time, choose a 1:1 ratio if possible.)

[0053] (2) Divide all the Chinese herbal decoctions obtained in (1) into two equal portions and take them warm half an hour after breakfast and dinner. Example 1 is more suitable for patients with milder symptoms, shorter disease course, and lighter weight.

[0054] Example 2

[0055] Similar to Example 1, the difference lies in the formulation of each Chinese herbal medicine ingredient as shown in Example 2 in Table 1. Example 2 is more suitable for patients with more severe conditions, longer disease courses, and heavier weight.

[0056] Example 3

[0057] Similar to Example 1, the difference lies in the formulation of each Chinese herbal medicine ingredient as shown in Example 3 in Table 1. Example 3 is more suitable for patients with more severe conditions, longer disease courses, and heavier weights.

[0058] Table 1. Distribution ratios of each group in Examples 1-3

[0059]

[0060]

[0061] There is no significant difference in the clinical effects of Examples 1-3, and they can all exert the following effects: (1) promoting qi and blood circulation to relieve pain, dispersing blood stasis and unblocking collaterals to relieve pain (where there is free flow, there is no pain); (2) tonifying the kidneys, strengthening muscles and bones to relieve pain (where there is nourishment, there is no pain).

[0062] Effect verification

[0063] This invention has been under development since 2010, undergoing annual clinical validation. Adhering to the principle of identifying and solving problems, and incorporating new clinical experience and discoveries, the version has been continuously optimized. By 2015, it had undergone three updates and iterations, resulting in the current version of the traditional Chinese medicine composition. The clinical effects of these three versions have been increasingly prominent, with each generation showing a higher efficacy rate. The clinical observation data are as follows.

[0064] 1. First generation version

[0065] 1.1 By weight, the traditional Chinese medicine composition includes the following components: 15 parts of Dioscorea opposita, 15 parts of Cornus officinalis, 15 parts of Rehmannia glutinosa (processed), 15 parts of Cinnamomum cassia, 10 parts of Angelica pubescens, 20 parts of Eucommia ulmoides (raw), 20 parts of Dipsacus asper, 20 parts of Drynaria fortunei, 15 parts of Boswellia carterii, 15 parts of Commiphora myrrha, 15 parts of Cyperus rotundus, 20 parts of Achyranthes bidentata, and 15 parts of Glycyrrhiza uralensis.

[0066] 1.2 Statistical Period

[0067] July 2010 - July 2012

[0068] 1.3 Statistical Objects (hereinafter the same):

[0069] Patients who visited the outpatient and inpatient departments of the Department of Traditional Chinese Medicine at the Seventh Medical Center of the PLA General Hospital during the aforementioned period, whose diagnoses included low back pain and one or more of the following: lumbar osteoproliferation, intervertebral disc herniation, lumbar hypertrophy, spinal stenosis, lumbar fracture, spinal tumor, acute or chronic lumbar injury or strain, lumbar muscle strain, and ankylosing spondylitis, and who used this oral Chinese medicine regimen.

[0070] 1.4 Evaluation of therapeutic effect (the same applies below):

[0071] 1.4.1 Observation indicators (the same below)

[0072] 1.4.1.1 Mini-Pain Questionnaire (MPQ): ① Pain Rating Index (PRI); ② Visual Analogue Scale (VAS); ③ Present Pain Intensity (PPI).

[0073] 1.4.1.2 Japanese Orthopaedic Association (JOA) Evaluation of Treatment Efficacy for Low Back Pain: The JOA is used to assess lumbar spine function before and after treatment. The total JOA score ranges from 0 to 29 points; a lower score indicates more severe functional impairment. The improvement rate is calculated based on the difference in JOA scores before and after treatment. Improvement rate = (Post-treatment score - Pre-treatment score) / (29 - Pre-treatment score) × 100%.

[0074] 1.4.1.3 Lumbar mobility score: The lumbar mobility score is used to assess the improvement of the patient's lumbar flexion, extension, lateral flexion and rotation before and after treatment. The higher the score, the more significant the improvement in mobility.

[0075] 1.4.2 Efficacy Evaluation Criteria: After one course of treatment, clinical efficacy evaluation criteria were formulated according to the requirements of the "Standards for Diagnosis and Efficacy of Diseases and Syndromes in Traditional Chinese Medicine" and the "Guiding Principles for Clinical Research of New Traditional Chinese Medicines". Cured: Symptoms in the lower back, buttocks, and limbs have basically disappeared; straight leg raise and reinforced test (±); able to work normally. Significantly Effective: Symptoms in the lower back, buttocks, and limbs have partially disappeared; no obvious tenderness points; straight leg raise and reinforced test (±); basically recovered to normal work. Improved: Mild lower back and leg pain; some symptoms have disappeared; straight leg raise test (±); may be accompanied by mild limitation of movement; able to perform some work. Ineffective: Symptoms in the lower back, buttocks, and limbs have not improved; straight leg raise test (+); unable to work. Total Effective Rate = (Number of Cured Cases + Number of Significantly Effective Cases + Number of Improved Cases) / Total Number of Cases × 100%. Cure Rate = Number of Cured Cases / Total Number of Cases × 100%.

[0076] 1.5. Usage Instructions (same below)

[0077] The traditional Chinese medicine decoction was prepared according to the method required in Example 1 and given to patients with acute and chronic low back pain. One course of treatment for acute patients was 2 weeks and one course of treatment for chronic patients was 6 weeks.

[0078] 1.6. Statistical Analysis of Clinical Outcome Data

[0079] The treatment results for acute low back pain are shown in Table 2:

[0080] Table 2

[0081]

[0082] The treatment results for chronic low back pain are shown in Table 3:

[0083] Table 3

[0084]

[0085] Note: Of the 5 cases of adverse reactions reported, all involved abdominal distension occurring approximately one week after starting medication. No other adverse reactions, especially serious ones, were observed during the statistical period. To further improve the efficacy and reduce the incidence of adverse reactions, the first-generation formulation was further optimized by adding Angelica sinensis and Ligusticum chuanxiong to enhance the effects of nourishing blood, promoting blood circulation, regulating qi, and relieving pain, and adding Citrus reticulata peel and Amomum villosum to regulate qi and harmonize the stomach, thereby reducing the impact of the herbal composition of this invention on the gastrointestinal tract, thus forming the second-generation version.

[0086] 2. Second generation version

[0087] 2.1 By weight, the traditional Chinese medicine composition comprises the following components: 15 parts of Dioscorea opposita, 15 parts of Cornus officinalis, 15 parts of Rehmannia glutinosa (processed), 15 parts of Cinnamomum cassia, 10 parts of Angelica pubescens, 20 parts of Eucommia ulmoides (raw), 20 parts of Dipsacus asper, 20 parts of Drynaria fortunei, 20 parts of Angelica sinensis, 15 parts of Ligusticum chuanxiong, 15 parts of Boswellia carterii, 15 parts of Commiphora myrrha, 15 parts of Cyperus rotundus, 20 parts of Achyranthes bidentata, 6 parts of Amomum villosum, 10 parts of Citrus reticulata peel, and 15 parts of Glycyrrhiza uralensis.

[0088] 2.2 Statistical Period

[0089] July 2012 - July 2015

[0090] 2.3 Statistical subjects (same as above):

[0091] Patients who visited the outpatient and inpatient departments of the Department of Traditional Chinese Medicine at the Seventh Medical Center of the PLA General Hospital during the aforementioned period, whose diagnoses included low back pain and one or more of the following: lumbar osteoproliferation, intervertebral disc herniation, lumbar hypertrophy, spinal stenosis, lumbar fracture, spinal tumor, acute or chronic lumbar injury or strain, lumbar muscle strain, and ankylosing spondylitis, and who used this oral Chinese medicine regimen.

[0092] 2.4 Evaluation of therapeutic effect (same as above)

[0093] 2.4.1 Observation indicators (same as above)

[0094] 2.4.1 Efficacy evaluation criteria (same as above)

[0095] 2.5. Usage method (same as above)

[0096] 2.6. Statistical Analysis of Clinical Outcome Data

[0097] The treatment results for acute low back pain are shown in Table 4:

[0098] Table 4

[0099]

[0100] The treatment results for chronic low back pain are shown in Table 5:

[0101] Table 5

[0102]

[0103] Note: After optimization to the second-generation traditional Chinese medicine composition, the overall effective rate was improved, and no adverse reactions, especially serious ones, were observed during the statistical period. Clinically, it was found that some patients with lower back pain also experienced local tissue edema. Combining modern pharmacology with the addition of Gentiana macrophylla and Polygala tenuifolia, this approach not only disperses blood stasis and reduces swelling but also effectively alleviates local tissue edema, forming the third-generation version, namely the traditional Chinese medicine composition of this invention.

[0104] 3. Third generation version

[0105] 3.1 The third-generation version is the combination ratio in Example 1.

[0106] 3.2 Statistical Period

[0107] July 2015 - October 2022

[0108] 3.3 Statistical Objects:

[0109] Patients who visited the outpatient and inpatient departments of the Department of Traditional Chinese Medicine at the Seventh Medical Center of the PLA General Hospital during the aforementioned period, whose diagnoses included low back pain and one or more of the following: lumbar osteoproliferation, intervertebral disc herniation, lumbar hypertrophy, spinal stenosis, lumbar fracture, spinal tumor, acute or chronic lumbar injury or strain, lumbar muscle strain, and ankylosing spondylitis, and who used this oral Chinese medicine regimen.

[0110] 3.4 Evaluation of therapeutic effect (same as above)

[0111] 3.4.1 Observation indicators (same as above)

[0112] 3.4.2 Efficacy evaluation criteria (same as above)

[0113] 3.5 The method described in Example 1

[0114] 3.6 Statistical Analysis of Clinical Outcome Data

[0115] The treatment results for acute low back pain are shown in Table 6:

[0116] Table 6

[0117]

[0118] The treatment results for chronic low back pain are shown in Table 7:

[0119] Table 7

[0120]

[0121] Note: The two cases of adverse reactions were due to abdominal distension caused by patients not taking the decoction after meals as required. The distension disappeared on its own after the patients adjusted to take the decoction after meals. There were no other adverse reactions or serious adverse reactions during the statistical period.

[0122] 3.7 Precautions

[0123] (1) This medicine is contraindicated for those who are allergic to any of the ingredients in the oral Chinese medicine formula of this invention or to honey.

[0124] (2) During the use of this plan, avoid using other traditional Chinese medicine preparations, decoctions or granules at the same time. If you take other Western medicines at the same time, you need to take them at least 1 hour apart.

[0125] (3) Note that the present invention should be taken half an hour after meals.

[0126] 3.8 Observation of therapeutic effects

[0127] General effects: For acute lower back pain, the pain is relieved after 3 days of use, and the symptoms basically disappear after 5-7 days. For severe cases, the symptoms basically disappear after about 2 weeks. For chronic lower back pain, the pain is relieved after 5-7 days, the symptoms are significantly relieved after about 2 weeks, and the pain basically disappears after 4 weeks. For patients with long-term lower back pain, the pain basically disappears after 6 weeks.

[0128] The above description is merely a preferred embodiment of the present invention and is not intended to limit the present invention in any way. Although the present invention has been disclosed above with reference to preferred embodiments, it is not intended to limit the present invention. Any person skilled in the art can make some modifications or alterations to the above-described technical content to create equivalent embodiments without departing from the scope of the present invention. Any simple modifications, equivalent changes, and alterations made to the above embodiments based on the technical essence of the present invention without departing from the scope of the present invention shall still fall within the scope of the present invention.

Claims

1. A traditional Chinese medicine composition for treating low back pain caused by musculoskeletal disorders, characterized in that, It is composed of the following components by weight: 10-15 parts of Dioscorea opposita, 10-15 parts of Cornus officinalis, 10-15 parts of Rehmannia glutinosa (processed), 10-15 parts of Cinnamomum cassia, 5-10 parts of Angelica pubescens, 15-20 parts of Eucommia ulmoides (raw), 15-20 parts of Dipsacus asper, 15-20 parts of Drynaria fortunei, 10-15 parts of Boswellia carterii, 10-15 parts of Commiphora myrrha, 10-15 parts of Ligusticum chuanxiong, 15-20 parts of Angelica sinensis, 10-15 parts of Cyperus rotundus, 15-20 parts of Achyranthes bidentata, 3-6 parts of Amomum villosum, 5-10 parts of Citrus reticulata peel, 10-15 parts of Gentiana macrophylla, 20-30 parts of Polygala tenuifolia, and 10-15 parts of Glycyrrhiza uralensis.

2. The traditional Chinese medicine composition for treating low back pain caused by musculoskeletal disorders according to claim 1, characterized in that, It is composed of the following components by weight: 15 parts of Dioscorea opposita, 15 parts of Cornus officinalis, 15 parts of Rehmannia glutinosa (processed), 15 parts of Cinnamomum cassia, 10 parts of Angelica pubescens, 20 parts of Eucommia ulmoides (raw), 20 parts of Dipsacus asper, 20 parts of Drynaria fortunei, 15 parts of Boswellia carterii, 15 parts of Commiphora myrrha, 15 parts of Ligusticum chuanxiong, 20 parts of Angelica sinensis, 15 parts of Cyperus rotundus, 20 parts of Achyranthes bidentata, 6 parts of Amomum villosum, 10 parts of Citrus reticulata peel, 15 parts of Gentiana macrophylla, 30 parts of Polygala tenuifolia, and 15 parts of Glycyrrhiza uralensis.

3. The use of a traditional Chinese medicine composition as described in claim 1 or 2 in the preparation of a medicament for treating low back pain caused by diseases of the musculoskeletal system.

4. A medication for treating lower back pain caused by musculoskeletal disorders, characterized in that, The raw materials consist of the traditional Chinese medicine composition as described in claim 1 or 2.

5. The drug according to claim 4, characterized in that, The drug also contains pharmaceutically acceptable excipients.

6. The drug according to claim 5, characterized in that, The excipients include excipients.

7. The drug according to claim 6, characterized in that, The excipient is honey.

8. The drug according to claim 5, characterized in that, The dosage form of the drug is decoction, tablet, pill, granule or capsule.

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