Model training method for depression detection, detection system, program, and storage medium

By constructing an artificial intelligence model based on small molecule compounds and using high-performance liquid chromatography-mass spectrometry detection technology, the problem of low accuracy in depression detection in existing technologies has been solved, achieving efficient and accurate depression risk assessment, which is suitable for clinical testing.

CN118230955BActive Publication Date: 2026-03-20HEFEI NOVA MS BIOTECH MEDICAL EQUIP CO LTD +1
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Patent Information

Application Number
CN202410430169.4
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2024-04-10
Publication Date
2026-03-20
Estimated Expiration
2044-04-10

AI Technical Summary

Technical Problem

Existing technologies for detecting depression suffer from low diagnostic accuracy, cumbersome signal acquisition, and difficulty in clinical application. There is a lack of efficient biomarker detection methods and artificial intelligence-assisted diagnostic technologies.

Method used

An artificial intelligence model was constructed using small molecule compounds such as 5-hydroxy-an-aminobenzoic acid, methionine, γ-aminobutyric acid, 3,4-dihydroxyphenylacetic acid, 2-pyrolinic acid, quinolinic acid, kynurenine, 5-hydroxytryptophan, 3-hydroxykynurenine, 3-hydroxy-an-aminobenzoic acid, dopamine, norepinephrine, and homocysteine ​​as biomarkers. The AI ​​model was trained with large sample data, and high-performance liquid chromatography and mass spectrometry were used to determine the concentration of compounds in the sample to assess the risk of depression.

Benefits of technology

It achieves high-precision and high-speed depression detection, with an AUC greater than 0.95 and an accuracy rate of over 90%. It simplifies the detection process, facilitates application in detection systems, and is suitable for use as an independent data processing unit or storage medium.

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Abstract

A kind of algorithm model for depression detection, detection system, program and storage medium.The training method of the artificial intelligence model includes: constructing artificial intelligence model, its input includes the concentration of 3-4 kinds of to-be-detected compounds selected from 5-hydroxyanthranilic acid, methionine, gamma-aminobutyric acid, 3,4-dihydroxyphenylacetic acid, 2-picolinic acid, quinolinic acid, kynurenine, 5-hydroxytryptamine, 3-hydroxykynurenine, 3-hydroxyanthranilic acid, dopamine, norepinephrine, homocysteine, and the output is the risk index of suffering from severe depression;Large sample data is used to train the artificial intelligence model.The AUC of the detection model of the application is greater than or equal to 0.95, even 0.99;Accuracy rate reaches more than 90%;High sensitivity;Algorithm is simple, iterative convergence is fast, is convenient for transplantation, can be embedded into detection system, also can be used as a single data processing unit, works using encryption key or external U disk mode.
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