A traditional Chinese medicine composition for treating inflammatory dermatosis and a preparation method thereof

By preparing a traditional Chinese medicine composition containing honeysuckle and other Chinese herbs, the balance of intestinal microbiota is regulated, which solves the problem of unsatisfactory effects of existing treatments for inflammatory skin diseases, and achieves the improvement of intestinal health and skin inflammation as well as anti-obesity effects.

CN118356459BActive Publication Date: 2025-12-09CHANGZHOU WUJIN PEOPLES HOSPITAL (CHANGZHOU EIGHTH PEOPLES HOSPITAL)
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Patent Information

Application Number
CN202410424745.4
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2024-04-10
Publication Date
2025-12-09
Estimated Expiration
2044-04-10

AI Technical Summary

Technical Problem

Existing medications for treating inflammatory skin diseases are not very effective, are difficult to cure completely, and have not effectively addressed the impact of gut microbiota imbalance on skin health.

Method used

A traditional Chinese medicine composition is used, which is made from raw materials such as honeysuckle, forsythia, rehmannia root, peony bark, red peony root, sophora flavescens, licorice, ophiopogon japonicus, codonopsis pilosula, hawthorn, scutellaria baicalensis, phellodendron bark, coptis chinensis, jujube seed, and uncaria. The medicine is prepared by decoction, concentration and addition of excipients. The berberine in coptis chinensis and phellodendron bark increases the abundance of specific intestinal flora and regulates the balance of intestinal microorganisms.

Benefits of technology

It significantly improves symptoms such as redness, swelling, heat, and pain in inflammatory skin diseases, enhances intestinal barrier function, reduces systemic inflammatory response, promotes skin healing, and has anti-obesity effects.

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Abstract

The application discloses a traditional Chinese medicine composition for treating inflammatory dermatosis and a preparation method thereof, which is mainly prepared from the following Chinese herbal medicine raw materials in parts by weight: 10-15 parts of honeysuckle, 9-14 parts of forsythia, 10-20 parts of radix rehmanniae, 10-22 parts of cortex moutan, 10-20 parts of red peony root, 18-25 parts of kuh-seng, 15-25 parts of licorice, 12-18 parts of ophiopogon, 6-14 parts of radix codonopsis, 10-18 parts of hawthorn, 10-20 parts of radix scrophulariae, 8-18 parts of phellodendron, 30-45 parts of rhizoma coptidis, 8-15 parts of spina date seed, 8-14 parts of Uncaria, and 10-16 parts of borneol; the application can promote the generation of SCFAs, maintain the balance of intestinal microbial community, meanwhile, the SCFAs are also helpful to maintain the integrity and function of intestinal epithelial cells, thereby enhancing the intestinal barrier function, reducing the harmful substances and pathogens into blood, reducing the systemic inflammatory response, so that the skin inflammation can be directly inhibited, the skin recovery can be promoted, and the body obesity of patients with high-sugar diet can be effectively inhibited.
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