A High-Efficiency Medical Wastewater Treatment Agent and Its Preparation Method

Abstract

This invention discloses a highly efficient medical wastewater treatment agent and its preparation method, belonging to the field of wastewater treatment technology. It includes a main agent and an auxiliary agent. The main agent is prepared through the following steps: Step S1, adding diethanolamine to methanol to obtain intermediate 1; Step S2, adding chloromethyl polystyrene resin to isopropanol, stirring at a uniform speed, and adding intermediate 1 to obtain an antibacterial matrix; Step S3, adding cobalt nitrate hexahydrate and trimesic acid to deionized water to obtain a precursor; Step S4, adding the antibacterial matrix and the precursor to a 10% (v / v) ethanol aqueous solution to obtain the main agent. Through the synergistic effect of the main agent and the auxiliary agent, it can efficiently treat medical wastewater. The precursor is an organic ligand of metallic cobalt, which can catalyze the activation effect of the auxiliary agent persulfate, thereby producing sulfate free radicals and forming a new advanced oxidation process that effectively treats antibiotic pollutants in medical wastewater.

Description

Technical Field

[0001] This invention relates to the field of wastewater treatment technology, specifically to a high-efficiency medical wastewater treatment agent and its preparation method. Background Technology

[0002] Currently, hospital wastewater has complex sources and compositions, posing significant health risks. The main sources are wastewater discharged from hospital treatment rooms, laboratories, wards, laundry rooms, X-ray rooms, and operating rooms. This wastewater contains large amounts of pathogenic bacteria, viruses, and pharmaceuticals, exhibiting characteristics of spatial pollution, acute infectiousness, and latent infectiousness. If hospital wastewater containing pathogenic microorganisms is discharged into urban sewers or environmental water bodies without disinfection, it often causes water pollution, triggering various diseases and infectious diseases, seriously endangering public health.

[0003] When using non-equilibrium plasma technology to treat medical wastewater, the liquid flow rate is too small due to the small size of the ionization space (i.e., the aperture of the liquid flow channel), which easily leads to a slow purification rate. Moreover, since the substances to be treated are all in the liquid phase, non-equilibrium plasma discharge failure is easily caused, resulting in purification failure. Furthermore, in existing plasma water purification technologies, sewage flows through the plasma electrode space and inevitably comes into contact with the electrodes, which will cause corrosion and failure of the electrodes.

[0004] When using biochemical treatment in aeration tanks, the traditional method for covering newly built medical wastewater aeration tanks is with concrete, while the traditional method for covering renovated hospital aeration tanks is with steel structure and inverted membrane. This method is costly, has a long installation period, and is complex. Aeration tanks using suspended chain aeration and oxygenation methods are inconvenient to cover directly with membranes because there are floating pipes on the water surface. In addition, the membrane is under heavy load during rainy or snowy weather, which can easily crush the floating pipes under the membrane.

[0005] Chinese patent application CN112723670A discloses a high-efficiency medical wastewater treatment process and application method, which removes organic matter from wastewater by combining biofilm free-flowing packing units. However, it cannot make targeted adjustments to the operating parameters during the removal of organic matter from wastewater, and the removal efficiency of organic matter from wastewater cannot be guaranteed. Summary of the Invention

[0006] To address the aforementioned technical problems, this invention provides a highly efficient medical wastewater treatment agent and its preparation method.

[0007] The objective of this invention can be achieved through the following technical solutions:

[0008] A highly efficient medical wastewater treatment agent includes a main agent and an auxiliary agent, wherein the main agent is prepared by the following steps:

[0009] Step S1: Add diethanolamine to methanol, stir at a constant speed for 15 min, add KH560, reflux for 6 h, remove methanol and unreacted KH560 by vacuum distillation after the reaction is completed to obtain intermediate 1. Control the ratio of diethanolamine, KH560 and methanol to 1-1.2 g: 10-15 mL: 80-100 mL.

[0010] In step S1, the secondary amine on diethanolamine reacts with the epoxy group on KH560 to generate intermediate 1;

[0011] Step S2: Add chloromethyl polystyrene resin to isopropanol, stir at a constant speed and add intermediate 1, heat to 65℃, keep the temperature for 36-48h, and after the reaction is completed, the antibacterial matrix is ​​obtained. Control the ratio of chloromethyl polystyrene resin, intermediate 1 and isopropanol to 5-10g: 1-1.5g: 100mL.

[0012] In step S2, macroporous cross-linked chloromethyl polystyrene resin is used as the matrix. The chlorine on the matrix reacts with the tertiary amine on intermediate 1 to form a quaternary ammonium salt, thereby obtaining the primary antibacterial matrix. It is a chloromethyl polystyrene resin grafted with a quaternary ammonium salt structure. The high specific surface area of ​​the macroporous cross-linked chloromethyl polystyrene resin itself can endow the matrix with excellent adsorption performance, which can physically adsorb the floating matter and large particles remaining after the purification of medical wastewater, and play a role in removing floating matter and large particles. The grafted quaternary ammonium salt structure can destroy the cell wall of microorganisms through the activity of ions, thereby achieving a bactericidal effect. It has a good killing effect on bacteria, viruses, fungi, etc., and thus treats bacteria and microorganisms in medical wastewater.

[0013] Step S3: Add cobalt nitrate hexahydrate and trimellitic acid to deionized water, add triethylamine, stir magnetically for 30 min, then heat to 90℃, stir at a constant speed and react for 24 h. After the reaction is completed, centrifuge the obtained reaction solution at 5000 r / min for 3 min, wash the filter cake three times with deionized water and anhydrous ethanol, and vacuum dry at 65℃ for 24 h to obtain the precursor. Control the ratio of cobalt nitrate hexahydrate, trimellitic acid, triethylamine and deionized water to be 1.42-1.45 g : 1-1.02 g : 1-2 g : 100 mL.

[0014] Step S4: Add the antibacterial matrix and precursor to a 10% (v / v) ethanol aqueous solution, add concentrated sulfuric acid, heat to 70-85℃, and keep the reaction at this temperature for 6-8 hours to obtain the main agent. Control the weight ratio of the antibacterial matrix, precursor and ethanol aqueous solution to be 1:0.3-0.5:100.

[0015] In step S4, the hydroxyl groups on the antibacterial matrix react with the carboxyl groups on the precursor under the catalysis of concentrated sulfuric acid to obtain the main agent. The precursor is connected to the antibacterial matrix by chemical bonds. The precursor is an organic ligand of metallic cobalt, which can catalyze the activation effect of the auxiliary persulfate, thereby producing sulfate free radicals. This forms a new advanced oxidation process that has a good treatment effect on antibiotic pollutants in medical wastewater.

[0016] Furthermore, the auxiliary agent is persulfate.

[0017] A highly efficient medical wastewater treatment agent is prepared through the following steps:

[0018] The main agent and auxiliary agent are mixed evenly at a weight ratio of 5:1 to obtain a high-efficiency medical wastewater treatment agent.

[0019] The beneficial effects of this invention are as follows: This invention prepares a highly efficient medical wastewater treatment agent. Through the synergistic effect of the main agent and the auxiliary agent, it can efficiently treat medical wastewater. The main agent is composed of an antibacterial matrix and a precursor. The hydroxyl groups on the antibacterial matrix react with the carboxyl groups on the precursor under the catalysis of concentrated sulfuric acid to obtain the main agent. The antibacterial matrix is ​​a chloromethyl polystyrene resin grafted with a quaternary ammonium salt structure. The high specific surface area of ​​the macroporous cross-linked chloromethyl polystyrene resin itself can endow the matrix with excellent adsorption properties, which can physically adsorb the floating matter and large particles remaining after the purification of medical wastewater, thereby removing floating matter and large particles. The grafted quaternary ammonium salt structure can destroy the cell wall of microorganisms through the activity of ions, thereby achieving a bactericidal effect. It has a good killing effect on bacteria, viruses, fungi, etc., and thus treats bacteria and microorganisms in medical wastewater. The precursor is an organic ligand of metallic cobalt, which can catalyze the activation effect of the auxiliary agent persulfate, thereby producing sulfate free radicals and forming a new advanced oxidation process that can effectively treat antibiotic pollutants in medical wastewater. Detailed Implementation

[0020] The technical solutions in the embodiments of the present invention will be clearly and completely described below. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention. Example 1

[0021] A highly efficient medical wastewater treatment agent, comprising a main agent and auxiliary agents, is prepared through the following steps:

[0022] The main agent and auxiliary agent are mixed evenly at a weight ratio of 5:1 to obtain a high-efficiency medical wastewater treatment agent.

[0023] The main agent is prepared through the following steps:

[0024] Step S1: Diethanolamine is added to methanol, stirred at a constant speed for 15 min, and then KH560 is added. The mixture is refluxed for 6 h. After the reaction is completed, methanol and unreacted KH560 are removed by vacuum distillation to obtain intermediate 1. The ratio of diethanolamine, KH560 and methanol is controlled to be 1 g: 10 mL: 80 mL.

[0025] Step S2: Add chloromethyl polystyrene resin to isopropanol, stir at a constant speed and add intermediate 1, heat to 65℃, keep warm for 36h, and after the reaction is completed, the antibacterial matrix is ​​obtained. Control the ratio of chloromethyl polystyrene resin, intermediate 1 and isopropanol to 5-10g:1g:100mL.

[0026] Step S3: Add cobalt nitrate hexahydrate and pyromellitic acid to deionized water, add triethylamine, stir magnetically for 30 min, then heat to 90℃, stir at a constant speed and react for 24 h. After the reaction is completed, centrifuge the prepared reaction solution at 5000 r / min for 3 min, wash the filter cake three times with deionized water and anhydrous ethanol, and vacuum dry at 65℃ for 24 h to obtain the precursor. Control the ratio of cobalt nitrate hexahydrate, pyromellitic acid, triethylamine and deionized water to be 1.42 g: 1 g: 1 g: 100 mL.

[0027] Step S4: Add the antibacterial matrix and precursor to a 10% (v / v) ethanol aqueous solution, add concentrated sulfuric acid, heat to 70°C, and keep the reaction at this temperature for 6 hours to obtain the main agent. Control the weight ratio of the antibacterial matrix, precursor, and ethanol aqueous solution to be 1:0.3:100.

[0028] The additive is sodium persulfate. Example 2

[0029] A highly efficient medical wastewater treatment agent, comprising a main agent and auxiliary agents, is prepared through the following steps:

[0030] The main agent and auxiliary agent are mixed evenly at a weight ratio of 5:1 to obtain a high-efficiency medical wastewater treatment agent.

[0031] The main agent is prepared through the following steps:

[0032] Step S1: Diethanolamine is added to methanol, stirred at a constant speed for 15 min, and then KH560 is added. The mixture is refluxed for 6 h. After the reaction is completed, methanol and unreacted KH560 are removed by vacuum distillation to obtain intermediate 1. The ratio of diethanolamine, KH560 and methanol is controlled to be 1.1 g: 12 mL: 90 mL.

[0033] Step S2: Add chloromethyl polystyrene resin to isopropanol, stir at a constant speed and add intermediate 1, heat to 65℃, keep the temperature for 36-48h, and after the reaction is completed, the antibacterial matrix is ​​obtained. Control the amount ratio of chloromethyl polystyrene resin, intermediate 1 and isopropanol to 8g:1.2g:100mL.

[0034] Step S3: Add cobalt nitrate hexahydrate and trimellitic acid to deionized water, add triethylamine, stir magnetically for 30 min, then heat to 90℃, stir at a constant speed and react for 24 h. After the reaction is completed, centrifuge the prepared reaction solution at 5000 r / min for 3 min, wash the filter cake three times with deionized water and anhydrous ethanol, and vacuum dry at 65℃ for 24 h to obtain the precursor. Control the ratio of cobalt nitrate hexahydrate, trimellitic acid, triethylamine and deionized water to be 1.44 g: 1.01 g: 1.5 g: 100 mL.

[0035] Step S4: Add the antibacterial matrix and precursor to a 10% (v / v) ethanol aqueous solution, add concentrated sulfuric acid, heat to 80°C, and keep the reaction at this temperature for 7 hours to obtain the main agent. Control the weight ratio of the antibacterial matrix, precursor, and ethanol aqueous solution to be 1:0.4:100.

[0036] The additive is sodium persulfate. Example 3

[0037] A highly efficient medical wastewater treatment agent, comprising a main agent and auxiliary agents, is prepared through the following steps:

[0038] The main agent and auxiliary agent are mixed evenly at a weight ratio of 5:1 to obtain a high-efficiency medical wastewater treatment agent.

[0039] The main agent is prepared through the following steps:

[0040] Step S1: Add diethanolamine to methanol, stir at a constant speed for 15 min, add KH560, reflux for 6 h, remove methanol and unreacted KH560 by vacuum distillation after the reaction is completed to obtain intermediate 1. The ratio of diethanolamine, KH560 and methanol is controlled to be 1.2 g: 15 mL: 100 mL.

[0041] Step S2: Add chloromethyl polystyrene resin to isopropanol, stir at a constant speed and add intermediate 1, heat to 65℃, keep warm for 48h, and after the reaction is completed, the antibacterial matrix is ​​obtained. The ratio of chloromethyl polystyrene resin, intermediate 1 and isopropanol is controlled to be 10g:1.5g:100mL.

[0042] Step S3: Add cobalt nitrate hexahydrate and pyromellitic acid to deionized water, add triethylamine, stir magnetically for 30 min, then heat to 90℃, stir at a constant speed and react for 24 h. After the reaction is completed, centrifuge the prepared reaction solution at 5000 r / min for 3 min, wash the filter cake three times with deionized water and anhydrous ethanol, and vacuum dry at 65℃ for 24 h to obtain the precursor. Control the ratio of cobalt nitrate hexahydrate, pyromellitic acid, triethylamine and deionized water to be 1.45 g: 1.02 g: 2 g: 100 mL.

[0043] Step S4: Add the antibacterial matrix and precursor to a 10% (v / v) ethanol aqueous solution, add concentrated sulfuric acid, heat to 85°C, and keep the reaction at this temperature for 8 hours to obtain the main agent. Control the weight ratio of the antibacterial matrix, precursor, and ethanol aqueous solution to be 1:0.5:100.

[0044] The additive is sodium persulfate.

[0045] Comparative Example 1

[0046] Compared with Example 3, this comparative example uses an antibacterial matrix as the main agent, and the preparation method of the high-efficiency medical wastewater treatment agent is as follows:

[0047] The antibacterial matrix prepared in Example 3 was mixed with the adjuvant at a weight ratio of 5:1 to obtain a high-efficiency medical wastewater treatment agent.

[0048] The additive is sodium persulfate.

[0049] Comparative Example 2

[0050] Compared with Example 3, this comparative example uses commercially available large-pore polystyrene resin as the main agent. The preparation method of the high-efficiency medical wastewater treatment agent is as follows:

[0051] A highly efficient medical wastewater treatment agent is prepared by uniformly mixing commercially available large-pore polystyrene resin and additives at a weight ratio of 5:1.

[0052] The additive is sodium persulfate.

[0053] The pre-filtered medical wastewater was added to the wastewater treatment agents prepared in Examples 1-3 and Comparative Examples 1-2 at a weight ratio of 500:1 and treated for 3 hours. After filtration, the wastewater was tested, and the results are shown in Table 1 below.

[0054] Table 1

[0055]

[0056] As can be seen from Table 1 above, the wastewater treatment agents prepared in Examples 1-3 of the present invention can adsorb floating matter in wastewater, and the introduced quaternary ammonium salt structure can destroy the cell wall of microorganisms, thereby achieving a bactericidal effect. It has a good killing effect on bacteria, viruses, fungi, etc. In addition, the synthesized precursor can also catalyze sodium persulfate to have a good degradation effect on antibiotic pollutants.

[0057] The above description is merely an example and illustration of the concept of the present invention. Those skilled in the art can make various modifications or additions to the specific embodiments described or use similar methods to replace them, as long as they do not deviate from the concept of the invention or exceed the scope defined in the claims, they should all fall within the protection scope of the present invention.

Claims

1. A highly effective medical sewage treatment agent, characterized by, The main agent is prepared by the following steps: Step S1, diethanolamine is added into methanol, after uniform stirring for 15 min, KH560 is added, reflux reaction is carried out for 6 h, after reaction is completed, vacuum distillation is carried out, and the intermediate 1 is prepared; Step S2, chloromethyl polystyrene resin is added into isopropyl alcohol, uniform stirring is carried out, and the intermediate 1 is added, temperature is raised to 65 DEG C, and incubation reaction is carried out for 36-48 h, after reaction is completed, the bacteriostatic matrix is prepared; Step S3, cobalt nitrate hexahydrate and trimesic acid are added into deionized water, triethylamine is added, magnetic stirring is carried out for 30 min, then temperature is raised to 90 DEG C, uniform stirring is carried out, and reaction is carried out for 24 h, after reaction is completed, the prepared reaction liquid is centrifuged at 5000 r / min for 3 min, the filter cake is washed with deionized water and anhydrous ethanol for three times, and vacuum drying is carried out at 65 DEG C for 24 h, and the precursor is prepared; Step S4, the bacteriostatic matrix and the precursor are added into 10% ethanol aqueous solution, concentrated sulfuric acid is added, temperature is raised to 70-85 DEG C, incubation reaction is carried out for 6-8 h, and the main agent is prepared; The auxiliary agent is persulfate.

2. The highly effective medical sewage treatment agent according to claim 1, characterized in that, In step S1, the amount ratio of diethanolamine, KH560 and methanol is controlled to be 1-1.2 g: 10-15 mL: 80-100 mL.

3. The high efficiency medical sewage treatment agent according to claim 1, characterized in that, In step S2, the amount ratio of chloromethyl polystyrene resin, the intermediate 1 and isopropyl alcohol is controlled to be 5-10 g: 1-1.5 g: 100 mL.

4. The highly effective medical sewage treatment agent according to claim 1, characterized in that, In step S3, the amount ratio of cobalt nitrate hexahydrate, trimesic acid, triethylamine and deionized water is controlled to be 1.42-1.45 g: 1-1.02 g: 1-2 g: 100 mL.

5. The highly effective medical sewage treatment agent according to claim 1, characterized in that, In step S4, the weight ratio of the bacteriostatic matrix, the precursor and the ethanol aqueous solution is controlled to be 1: 0.3-0.5:

100.

6. A method of preparing the highly effective medical sewage treatment agent according to any one of claims 1 to 5, characterized by, The main agent and the auxiliary agent are mixed uniformly according to the weight ratio of 5:1, and the high-efficiency medical sewage treatment agent is prepared. The main agent and the auxiliary agent are mixed uniformly according to the weight ratio of 5:1, and the high-efficiency medical sewage treatment agent is prepared.

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