Traditional Chinese medicine composition and application thereof in preparation of product with hangover alleviating effect
By replacing Pueraria root with Pueraria and adding Citrus seeds, the acetaldehyde dehydrogenase activity of the traditional Chinese medicine composition is improved, and the problem of insufficient acetaldehyde dehydrogenase activity of the existing traditional Chinese medicine composition is solved, and a significant improvement in the slag is achieved. Effects and effects of SOD enzyme activity.
Patent Information
- Application Number
- CN202411453964.1
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2024-10-17
- Publication Date
- 2025-01-10
AI Technical Summary
The existing traditional Chinese medicine compositions are not effective in improving the activity of acetaldehyde dehydrogenase, which affects the effect of quenching wine.
By combining Pueraria root, chrysanthemum, mulberry leaves, scorched gardenia, orange red, sacred leaf, sacred leaf, hordeum, licorice, eucommia ulmoides, raspberry and Ganoderma lucidum, and replace Pueraria root with Pueraria root with Pueraria root, and add Citrus tangerine peel on the basis of it. to form new traditional Chinese medicine compositions to improve the activities of acetaldehyde dehydrogenase and ethanol dehydrogenase.
It significantly improves the activities of acetaldehyde dehydrogenase and ethanol dehydrogenase, enhances the effect of understanding wine, and has good SOD enzyme activity, which can effectively accelerate alcohol metabolism without the need for other hangover products.
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Figure BDA0005089935970000091 
Figure BDA0005089935970000101
Abstract
Description
Technical Field
[0001] The present invention relates to the technical field of traditional Chinese medicines, and in particular to a traditional Chinese medicine composition and application thereof in preparing a product having an alcohol sobering effect. Background Art
[0002] Alcohol is a common beverage in human life. Due to differences in the body's ability to metabolize alcohol, people's alcohol tolerance also varies. However, excessive drinking can lead to drunkenness. Sobering up refers to recovering from a drunken state, restoring consciousness or self-control. Currently, there are three methods for sobering up: oxygen therapy, medication, and natural sobering up. Medication is an effective method.
[0003] The main metabolic pathway of alcohol in the body is as follows: alcohol is first metabolized into acetaldehyde by alcohol dehydrogenase; then, acetaldehyde dehydrogenase metabolizes acetaldehyde into acetic acid, and finally, acetic acid is metabolized into carbon dioxide and water through the tricarboxylic acid cycle. Therefore, increasing the activity of acetaldehyde dehydrogenase and acetaldehyde dehydrogenase is important for improving alcohol metabolism and accelerating hangover relief. Increasing the activity of acetaldehyde dehydrogenase and acetaldehyde dehydrogenase also achieves the goal of hangover relief from the root cause.
[0004] Because traditional Chinese medicine contains numerous active ingredients and has the advantage of minimal side effects, it is currently one of the key research directions for hangover relief products. Therefore, the development of a traditional Chinese medicine composition with acetaldehyde dehydrogenase and acetaldehyde dehydrogenase activity using traditional Chinese medicine as raw materials has important application value. Summary of the Invention
[0005] In order to overcome at least one of the technical problems existing in the prior art, the present invention provides a traditional Chinese medicine composition and its application in preparing a product with alcohol sobering effect.
[0006] The technical solutions of the present invention are as follows:
[0007] The present invention first provides a traditional Chinese medicine composition, which comprises the following traditional Chinese medicine components: kudzu root, chrysanthemum, mulberry leaf, scorched gardenia, tangerine peel, perilla leaf, imperata root, patchouli, liquorice, eucommia male flower, raspberry and ganoderma.
[0008] The inventors discovered that a composition obtained by combining kudzu root, chrysanthemum, mulberry leaf, charred gardenia, tangerine peel, perilla leaf, imperata root, patchouli, licorice root, eucommia male flower, raspberry, and ganoderma lucidum exhibits excellent alcohol dehydrogenase activity. Studies have shown that this composition exhibits significantly higher alcohol dehydrogenase activity than the reference substances, Neptune Jinzun brand oyster soybean peptide carnitine oral liquid and Neptune Jinzun tablets. However, the aldehyde dehydrogenase activity of the composition obtained by combining kudzu root, chrysanthemum, mulberry leaf, charred gardenia, tangerine peel, perilla leaf, imperata root, patchouli, licorice root, eucommia male flower, raspberry, and ganoderma lucidum is not particularly high, and further improvement is needed.
[0009] Based on the fact that the above-mentioned traditional Chinese medicine composition has very excellent alcohol dehydrogenase activity; in the specific application process of hangover relief, the above-mentioned composition of the present invention can be combined with other hangover relief products with high activity against acetaldehyde dehydrogenase, which can greatly improve alcohol metabolism and enhance the hangover relief effect.
[0010] Preferably, the traditional Chinese medicine composition comprises the following traditional Chinese medicine components in parts by weight:
[0011] 10-20 parts of Pueraria root, 3-6 parts of chrysanthemum, 3-6 parts of mulberry leaf, 3-6 parts of scorched gardenia, 1-5 parts of dried orange peel, 1-3 parts of perilla leaf, 1-5 parts of imperata root, 1-2 parts of patchouli, 1-2 parts of liquorice, 1-3 parts of eucommia ulmoides flower, 1-3 parts of raspberry, and 1-3 parts of ganoderma lucidum.
[0012] Preferably, the traditional Chinese medicine composition comprises the following traditional Chinese medicine components in parts by weight:
[0013] 15-20 parts of Pueraria root, 5-6 parts of chrysanthemum, 5-6 parts of mulberry leaf, 5-6 parts of scorched gardenia, 3-5 parts of dried orange peel, 1-2 parts of perilla leaf, 1-3 parts of imperata root, 1-2 parts of patchouli, 1-2 parts of liquorice, 1-3 parts of eucommia ulmoides flower, 1-3 parts of raspberry, and 1-3 parts of ganoderma lucidum.
[0014] Most preferably, the Chinese medicine composition comprises the following Chinese medicine components in parts by weight:
[0015] 15 parts of Puerariae Radix, 5 parts of chrysanthemums, 5 parts of mulberry leaves, 5 parts of scorched Gardenia Fructus, 3 parts of dried orange peel, 2 parts of perilla leaves, 3 parts of Imperatae Rhizoma, 1 part of Patchouli, 2 parts of liquorice, 2 parts of ganoderma lucidum.
[0016] Preferably, the Chinese medicine composition replaces the kudzu root with kudzu flower, and
[0017] It also includes Hovenia dulcis and Gardenia jasminoides.
[0018] Based on the defect of low activity on alcohol dehydrogenase of the composition obtained by compounding kudzu root, chrysanthemum, mulberry leaf, charred gardenia, tangerine peel, perilla leaf, imperata root, patchouli, licorice, eucommia male flower, raspberry and ganoderma lucidum, the inventors found in continuous research and exploration that, based on the composition obtained by compounding kudzu root, chrysanthemum, mulberry leaf, charred gardenia, tangerine peel, perilla leaf, imperata root, patchouli, licorice and ganoderma, the kudzu root is replaced with kudzu flower and Hovenia dulcis fruit is further added; the activity of the traditional Chinese medicine composition on acetaldehyde dehydrogenase can be greatly improved, and the composition also has very excellent alcohol dehydrogenase activity, and its alcohol dehydrogenase activity is also significantly higher than that of the reference substances Neptune Jinzun brand oyster soybean peptide carnitine oral liquid and Neptune Jinzun tablets.
[0019] Preferably, the traditional Chinese medicine composition comprises the following traditional Chinese medicine components in parts by weight:
[0020] 10-20 parts of kudzu flower, 3-6 parts of chrysanthemum, 3-6 parts of mulberry leaf, 3-6 parts of kudzu root, 1-5 parts of orange peel, 1-3 parts of perilla leaf, 1-5 parts of imperata rhizome, 1-2 parts of patchouli, 1-2 parts of liquorice, 1-3 parts of eucommia male flower, 1-3 parts of raspberry, 1-3 parts of ganoderma lucidum, 3-6 parts of hovenia dulcis fruit, and 1-2 parts of scorched gardenia.
[0021] Preferably, the Chinese medicine composition comprises the following Chinese medicine components in parts by weight:
[0022] 15-20 parts of kudzu flower, 5-6 parts of chrysanthemum, 5-6 parts of mulberry leaf, 5-6 parts of kudzu root, 3-5 parts of dried orange peel, 1-2 parts of perilla leaf, 1-3 parts of imperata rhizome, 1-2 parts of patchouli, 1-2 parts of liquorice, 1-3 parts of eucommia male flower, 1-3 parts of raspberry, 1-3 parts of ganoderma lucidum, 3-5 parts of hovenia dulcis fruit, and 1-2 parts of scorched gardenia.
[0023] Most preferably, the Chinese medicine composition comprises the following Chinese medicine components in parts by weight:
[0024] 15 parts of Pueraria lobata flowers, 5 parts of chrysanthemum flowers, 5 parts of mulberry leaves, 5 parts of kudzu roots, 3 parts of orange peel, 2 parts of perilla leaves, 3 parts of imperata rhizome, 1 part of patchouli, 2 parts of liquorice, 2 parts of Eucommia ulmoides flowers, 2 parts of raspberry fruits, 2 parts of ganoderma lucidum, 5 parts of Hovenia dulcis fruits, and 1 part of scorched Gardenia jasminoides.
[0025] Preferably, the composition can be taken by soaking or boiling in boiling water during specific use.
[0026] Preferably, the composition can be further processed by the following method:
[0027] The preparation method of the Chinese medicine composition further comprises the following steps:
[0028] The above Chinese medicines are mixed and extracted with water or ethanol. After the extraction is completed, the extract is collected and concentrated and dried to obtain the Chinese medicine composition.
[0029] Preferably, the ethanol is ethanol with a volume fraction of 50% to 95%.
[0030] Preferably, the extraction is carried out at 70-90°C.
[0031] The present invention also provides a method for preparing the above-mentioned Chinese medicine composition having the function of improving ethanol dehydrogenation.
[0032] Application of enzyme active products.
[0033] The present invention also provides an application of the traditional Chinese medicine composition in preparing a product capable of improving the activity of acetaldehyde dehydrogenase.
[0034] The present invention also provides a method for preparing the above-mentioned Chinese medicine composition having the function of increasing SOD enzyme activity.
[0035] Sexual products
[0036] Application in products.
[0037] The present invention also provides a method for preparing a product having the effect of sobering up
[0038] Application in products.
[0039] Preferably, the product is a substitute tea, a compressed candy, a solid beverage, a beverage, a
[0040] health products
[0041] or medication.
[0042] Beneficial effects: The present invention provides a new Chinese medicine composition; research shows that
[0043] In the
[0044] The Chinese medicine composition has the activity of acetaldehyde dehydrogenase and acetaldehyde dehydrogenase; therefore, it has important application value as a hangover product. Further research also shows that the Chinese medicine composition also has a good SOD enzyme activity. DETAILED DESCRIPTION
[0045] The present invention is further explained below with reference to specific examples, but the examples do not limit the present invention in any form.
[0046] Example 1 Chinese medicine composition
[0047] The Chinese medicinal raw materials are composed of 15 parts of kudzu root, 5 parts of chrysanthemum, 5 parts of mulberry leaf, 5 parts of scorched gardenia, 3 parts of orange peel, 2 parts of perilla leaf, 3 parts of imperata rhizome, 1 part of patchouli, 2 parts of liquorice, 2 parts of eucommia male flower, 2 parts of raspberry, and 2 parts of ganoderma.
[0048] The Chinese medicinal raw materials in the above parts by weight are mixed and ground into powder, and then mixed evenly to obtain the Chinese medicinal composition.
[0049] Example 2 Chinese medicine composition
[0050] The Chinese medicinal raw materials are composed of the following parts by weight: 15 parts of kudzu flower, 5 parts of chrysanthemum, 5 parts of mulberry leaf, 5 parts of kudzu root, 3 parts of orange peel, 2 parts of perilla leaf, 3 parts of imperata rhizome, 1 part of patchouli, 2 parts of liquorice, 2 parts of eucommia male flower, 2 parts of raspberry, 2 parts of ganoderma lucidum, 5 parts of hovenia dulcis fruit, and 1 part of scorched gardenia.
[0051] The Chinese medicinal raw materials in the above parts by weight are mixed and ground into powder, and then mixed evenly to obtain the Chinese medicinal composition.
[0052] Example 3 Chinese medicine composition
[0053] The Chinese medicinal raw materials are composed of 10 parts of kudzu root, 6 parts of chrysanthemum, 6 parts of mulberry leaf, 6 parts of scorched gardenia, 1 part of orange peel, 1 part of perilla leaf, 1 part of imperata root, 2 parts of patchouli, 1 part of liquorice, 1 part of eucommia male flower, 1 part of raspberry, and 1 part of ganoderma lucidum.
[0054] The Chinese medicinal raw materials in the above parts by weight are mixed and ground into powder, and then mixed evenly to obtain the Chinese medicinal composition.
[0055] Example 4 Chinese medicine composition
[0056] The Chinese medicinal raw materials are composed of the following parts by weight: 20 parts of kudzu root, 3 parts of chrysanthemum, 3 parts of mulberry leaf, 3 parts of scorched gardenia, 5 parts of dried orange peel, 3 parts of perilla leaf, 5 parts of imperata rhizome, 1 part of patchouli, 2 parts of liquorice, 3 parts of eucommia male flower, 3 parts of raspberry, and 3 parts of ganoderma lucidum.
[0057] The Chinese medicinal raw materials in the above parts by weight are mixed and ground into powder, and then mixed evenly to obtain the Chinese medicinal composition.
[0058] Example 5 Chinese medicine composition
[0059] The Chinese medicinal raw materials are composed of the following parts by weight: 10 parts of kudzu flower, 6 parts of chrysanthemum, 6 parts of mulberry leaf, 6 parts of kudzu root, 1 part of orange peel, 1 part of perilla leaf, 1 part of imperata rhizome, 2 parts of patchouli, 1 part of liquorice, 1 part of eucommia male flower, 1 part of raspberry, 1 part of ganoderma lucidum, 3 parts of hovenia dulcis fruit, and 2 parts of scorched gardenia.
[0060] The Chinese medicinal raw materials in the above parts by weight are mixed and ground into powder, and then mixed evenly to obtain the Chinese medicinal composition.
[0061] Example 6 Chinese medicine composition
[0062] The Chinese medicinal raw materials are composed of the following parts by weight: 20 parts of kudzu flower, 3 parts of chrysanthemum, 3 parts of mulberry leaf, 3 parts of kudzu root, 5 parts of orange peel, 3 parts of perilla leaf, 5 parts of imperata rhizome, 1 part of patchouli, 2 parts of liquorice, 3 parts of eucommia male flower, 3 parts of raspberry, 3 parts of ganoderma lucidum, 6 parts of hovenia dulcis fruit, and 1 part of scorched gardenia.
[0063] The Chinese medicinal raw materials in the above parts by weight are mixed and ground into powder, and then mixed evenly to obtain the Chinese medicinal composition.
[0064] Experimental example
[0065] The test method for alcohol dehydrogenase (ADH) activity is:
[0066] The sample to be tested was crushed, passed through a 60-mesh sieve, and extracted with 20 times the volume of 750 mL / L ethanol at 80°C for 2 h. The extraction was repeated twice. The filtrates were combined and concentrated under reduced pressure. The extracts were evaporated to dryness in a water bath to obtain the extracts for later use.
[0067] ADH activity was determined using a modified Valle-Hoch method. To a stoppered test tube, add 1.5 ml of sodium pyrophosphate buffer, 1.0 ml of NAD+, and 0.5 ml of ethanol. Add a solution containing 0.003 g / mL of the extract to be tested or 0.1, 0.2, 0.3, or 0.4 ml of Neptune Golden Zun brand oyster soybean peptide carnitine oral solution, respectively. Mix and incubate at 37°C with a lid for 5 minutes. Immediately add 0.1 ml of ADH to the stoppered test tube after incubation. Replace the ADH solution with distilled water in a control tube. Shake well, incubate at 37°C for 5 minutes, and measure the absorbance (A340). Read the absorbance every 30 seconds for 5 minutes. Use the control tube as the zero point, and calculate the average absorbance per minute (ΔA / min).
[0068] ADH activity (U / mL) = ΔA / min × V / M × 1 / 6.22 × 0.5 × 10 3
[0069] Where: V is the total reaction volume; M is the sample amount; △A / min is the average absorbance value per minute.
[0070] The test method for acetaldehyde dehydrogenase (ALDH) activity is:
[0071] The raw materials were dried in a 60°C constant-temperature drying oven for 4 hours, pulverized using a traditional Chinese medicine grinder, and passed through an 80-mesh sieve to obtain a powder. The raw material powders were weighed separately and added to 70% ethanol at a solid-liquid ratio of 1:20. The stoppered conical flask was gently shaken to uniformly dissolve the powder in the ethanol solution. Ultrasonic-assisted extraction was then performed at room temperature for 30 minutes. After the first extraction, the resulting extract was centrifuged at 3000 rpm for 10 minutes. The supernatant was collected, and the residue was added to 70% ethanol at a solid-liquid ratio of 1:10. A second ultrasonic extraction was performed at 80°C for the same 30 minutes. The resulting extract was centrifuged, the residue discarded, and the supernatant combined with the supernatant from the first extraction. Ethanol was removed by rotary evaporation at 45°C and concentrated under reduced pressure. The concentrate was dried under vacuum at room temperature to obtain an extract concentrate, which was stored in a refrigerator at 4°C until further use.
[0072] A modified Blair & Bodley method (Li et al., 2014) was used. To each assay tube, 1.6 mL of 100 mM sodium pyrophosphate buffer (pH 9.5), 1 mL of 3.6 mM oxidized coenzyme I (NAD+), 0.1 mL of 100 mM acetaldehyde solution, 0.1 mL of 10 mM pyrazole, and 0.1 mL of 30 mg / mL sample solution were added. After mixing, the tube was placed in a 30°C water bath, covered, and incubated for 5 minutes. 0.1 mL of 18 mM ALDH was then added to the tube, shaken, and immediately measured using a spectrophotometer to determine the absorbance (A340). Readings were taken every 1 minute until the absorbance increase per minute reached a stable value. The A value was plotted against time, and the increase in A340 / 1 minute was calculated. The enzyme activity units were calculated based on the molar absorptivity of NADH at 340 nm of 6.22. The ALDH activation rate was calculated as follows:
[0073]
[0074] Where: V is the volume of the total reaction solution (mL);
[0075] DF is the dilution factor;
[0076] 6.22 is the millimolar extinction coefficient of NADH at a wavelength of 340 nm;
[0077] 0.1 is the volume of the enzyme solution (mL).
[0078] The test method for SOD enzyme activity is:
[0079] The sample was pulverized, passed through a 60-mesh sieve, and extracted twice with 20 volumes of 750 mL / L ethanol at 80°C for 2 h under reflux. The filtrates were combined, concentrated under reduced pressure, and evaporated to dryness in a water bath to obtain an extract for later use. Determination of the autooxidation rate: To 4.5 mL of 50 mmol / L Tris-HCl buffer solution (pH 8.2) at 25°C, 10 μL of 50 mmol / L pyrogallol was added. The mixture was rapidly shaken and poured into a cuvette. The Tris-HCl buffer solution was used as a blank control. The absorbance was measured at 325 nm, with measurements taken every 30 seconds for a total of 6 measurements. Determination of enzyme activity: At 25°C, add a solution containing 0.03g / mL of the extract to be tested or 0.1mL of Haiwang Jinzun brand oyster soybean peptide carnitine oral solution to 4.5mL of 50mmol / l Tris-HCl buffer solution (pH 8.2), then add 40μL of SOD enzyme solution, preheat for 20min, add 10μL of 50mmol / l pyrogallol, shake quickly, and pour into a cuvette.
[0080] Using Tris-HCl buffer as a blank control, measure absorbance at 325 nm, every 30 seconds for a total of six measurements. Calculate the rate of change in optical density (OD / min) to evaluate SOD activity (the rate of change in optical density (OD / min) is inversely proportional to SOD activity).
[0081] Table 1. Activity test results
[0082]
[0083] As shown in the experimental results in Table 1, the ADH activity of the traditional Chinese medicine composition in Example 1 is significantly higher than that of Neptune Jinzun Oyster Soy Peptide Carnitine Oral Liquid and Neptune Jinzun Tablets; however, its ALDH activity is far lower than that of Neptune Jinzun Oyster Soy Peptide Carnitine Oral Liquid and Neptune Jinzun Tablets. This indicates that the composition obtained by combining Pueraria lobata, Chrysanthemum Flos, Mulberry Leaf, Gardenia jasminoides, Dried Tangerine Peel, Perilla Leaf, Imperata Root, Crataegus pinnatifida, Patchouli Root, Licorice Root, and Ganoderma lucidum has excellent alcohol dehydrogenase activity, significantly higher than that of the control substances Neptune Jinzun Oyster Soy Peptide Carnitine Oral Liquid and Neptune Jinzun Tablets. However, the composition obtained by combining Pueraria lobata, Chrysanthemum Flos, Mulberry Leaf, Gardenia jasminoides, Dried Tangerine Peel, Perilla Leaf, Imperata Root, Crataegus pinnatifida, Patchouli Root, Licorice Root, and Ganoderma lucidum does not exhibit particularly high aldehyde dehydrogenase activity, which warrants further improvement.
[0084] Based on the above-mentioned Example 1, the Chinese medicine composition has very excellent alcohol dehydrogenase activity; in the specific hangover application process, the above-mentioned composition of the present invention can be combined with other hangover products with high activity on acetaldehyde dehydrogenase. For example, the Chinese medicine composition of the present invention can be taken first to accelerate ethanol metabolism, and then used in combination with Neptune Jinzun brand oyster soybean peptide carnitine oral liquid or Neptune Jinzun tablets or other hangover products with high activity on acetaldehyde dehydrogenase; this can greatly improve alcohol metabolism and enhance the hangover effect.
[0085] As can be seen from the experimental results in Table 1, the ALDH activity of the Chinese medicine composition of Example 2 is significantly higher than that of the Chinese medicine composition of Example 1. Based on the composition obtained by compounding kudzu root, chrysanthemum, mulberry leaf, charred gardenia, tangerine peel, perilla leaf, imperata root, hawthorn, patchouli, liquorice and ganoderma, the kudzu root is replaced with kudzu flower, and Hovenia dulcis fruit is further added. This can significantly improve the activity of the Chinese medicine composition against acetaldehyde dehydrogenase. At the same time, it also has very excellent alcohol dehydrogenase activity, and its alcohol dehydrogenase activity is also significantly higher than that of the reference substances Neptune Jinzun brand oyster soybean peptide carnitine oral solution and Neptune Jinzun tablets.
[0086] It can be seen that the Chinese medicine composition of Example 2 not only has very excellent alcohol dehydrogenase activity, but also has very excellent acetaldehyde dehydrogenase activity; therefore, compared with the Chinese medicine composition of Example 1, in the specific hangover application process, it can be used without being used in combination with other hangover products with high activity against acetaldehyde dehydrogenase.
[0087] In addition, it can be seen from Table 1 that the SOD activity of the Chinese medicine compositions of Examples 1 and 2 is comparable to that of the Neptune Jinzun brand oyster soybean peptide carnitine oral solution.
Claims
1. A Chinese medicine composition, characterized in that: It contains the following Chinese medicinal ingredients: kudzu root, chrysanthemum, mulberry leaf, scorched gardenia, tangerine peel, perilla leaf, imperata root, patchouli, licorice, eucommia male flower, raspberry and ganoderma lucidum.
2. The Chinese medicine composition according to claim 1, characterized in that: Contains the following Chinese medicine components in parts by weight: 10-20 parts of Pueraria root, 3-6 parts of chrysanthemum, 3-6 parts of mulberry leaf, 3-6 parts of scorched gardenia, 1-5 parts of orange peel, 1-3 parts of perilla leaf, 1-5 parts of Imperata root, 1-2 parts of Patchouli, 1-2 parts of liquorice, 1-3 parts of Eucommia ulmoides flower, 1-3 parts of raspberry, and 1-3 parts of Ganoderma lucidum.
3. The Chinese medicine composition according to claim 1, characterized in that Contains the following Chinese medicine components in parts by weight: 15-20 parts of Pueraria root, 5-6 parts of chrysanthemum, 5-6 parts of mulberry leaf, 5-6 parts of scorched gardenia, 3-5 parts of orange peel, 1-2 parts of perilla leaf, 1-3 parts of Imperata root, 1-2 parts of Patchouli, 1-2 parts of liquorice, 1-3 parts of Eucommia ulmoides flower, 1-3 parts of raspberry, and 1-3 parts of Ganoderma lucidum. Most preferably, the Chinese medicine composition comprises the following Chinese medicine components in parts by weight: 15 parts of Puerariae Radix, 5 parts of chrysanthemum, 5 parts of mulberry leaves, 5 parts of scorched gardenias, 3 parts of orange peel, 2 parts of perilla leaves, 3 parts of imperata rhizome, 1 part of patches, 2 parts of liquorice, 2 parts of eucommia male flowers, 2 parts of rubus idaeus, and 2 parts of ganoderma lucidum.
4. The Chinese medicine composition according to claim 1, characterized in that: The kudzu root is replaced with kudzu flower, and the kudzu flower is also included.
5. The Chinese medicine composition according to claim 4, characterized in that: Contains the following Chinese medicine components in parts by weight: 10-20 parts of kudzu flower, 3-6 parts of chrysanthemum, 3-6 parts of mulberry leaf, 3-6 parts of kudzu root, 1-5 parts of orange peel, 1-3 parts of perilla leaf, 1-5 parts of imperata root, 1-2 parts of patchouli, 1-2 parts of liquorice, 1-3 parts of eucommia male flower, 1-3 parts of raspberry, 1-3 parts of ganoderma lucidum, 3-6 parts of hovenia dulcis, and 1-2 parts of gardenia jasminoides.
6. The Chinese medicine composition according to claim 5, characterized in that: Contains the following Chinese medicine components in parts by weight: 15-20 parts of kudzu flower, 5-6 parts of chrysanthemum, 5-6 parts of mulberry leaf, 5-6 parts of kudzu root, 3-5 parts of orange peel, 1-2 parts of perilla leaf, 1-3 parts of imperata root, 1-2 parts of patchouli, 1-2 parts of liquorice, 1-3 parts of eucommia ulmoides flower, 1-3 parts of raspberry, 1-3 parts of ganoderma lucidum, 3-5 parts of hovenia dulcis, and 1-2 parts of gardenia jasminoides. Most preferably, the Chinese medicine composition comprises the following Chinese medicine components in parts by weight: 15 parts of pueraria flowers, 5 parts of chrysanthemums, 5 parts of mulberry leaves, 5 parts of kudzu roots, 3 parts of orange peel, 2 parts of perilla leaves, 3 parts of imperata rhizomes, 1 part of patches, 2 parts of liquorice, 2 parts of eucommia male flowers, 2 parts of rubus idaeus, 2 parts of ganoderma lucidum, 5 parts of hovenia dulcis seeds, and 1 part of gardenia jasminoides.
7. Use of the Chinese medicine composition according to any one of claims 1 to 6 in the preparation of a product having the ability to increase the activity of alcohol dehydrogenase.
8. Use of the traditional Chinese medicine composition according to any one of claims 1 to 6 in the preparation of a product having the ability to increase the activity of acetaldehyde dehydrogenase.
9. Use of the Chinese medicine composition according to any one of claims 1 to 6 in the preparation of a product having the ability to increase SOD enzyme activity.
10. Use of the Chinese medicine composition according to any one of claims 1 to 6 in the preparation of a product having an alcohol sobering effect.