A reaction control phase transfer catalyst, a preparation method thereof and a method for catalytically synthesizing 2-pyrazoline

Abstract

This invention proposes a reaction-controlled phase transfer catalyst, its preparation method, and a method for catalytic synthesis of 2-pyrazoline, belonging to the technical field of the aerospace industry. It addresses the technical problems of difficult separation and recovery, poor reusability, and easy loss of solid catalysts. The preparation method of the reaction-controlled phase transfer catalyst of this invention includes the following steps: mixing and dissolving a bidentate nitrogen heterocyclic compound, an organic sulfonic acid, and a solvent; then reacting; after the reaction is complete, rotary evaporation and washing are performed to precipitate crystals, which are then dried to obtain the reaction-controlled phase transfer catalyst. The reaction-controlled phase transfer catalyst of this invention is a type of unconventional ionic liquid that is solid at room temperature. It is applied for the first time to the catalytic synthesis of 2-pyrazoline. In this reaction, the novel reaction-controlled phase transfer catalyst exhibits a unique liquid-solid self-separation phenomenon, achieving enhanced coupling between reaction and separation, and guiding a highly efficient and green synthesis reaction process. More importantly, it achieves stable precipitation with high recovery rate of the reaction-controlled phase transfer catalyst, realizing the invention's objective of catalyst reuse, and overcoming the problems of greening, energy saving, and low overall cost in processes using traditional inorganic / organic acid catalysts and solid catalysts widely used in industry.