A plasma collection system

Abstract

The application discloses a kind of plasma collection systems, belongs to the field of plasma collection.A kind of plasma collection system, including equipment box, still including separation box being fixed in the top of equipment box, separation box is provided with the filter part of separating blood and plasma in, wherein, the top of separation box is provided with liquid storage ring, drop adding part for adding anticoagulant into separation box is set on the liquid storage ring;Refrigerator is fixed on the equipment box, refrigeration bin is opened in the side wall of equipment box, and the output end of refrigerator is communicated with the inner cavity of refrigeration bin;The repulsion of piston plate and magnetic plate makes the air pressure in separation box continuously reduce, so that blood moves more quickly into separation box, effectively improves blood collection efficiency;And cooperate with rotary shaft to drive filter hopper to rotate, so that filter hopper generates centrifugal force effect, so that plasma component in blood more quickly and effectively passes through filter membrane, effectively improves separation effect.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of plasma collection, in particular to a plasma collection system. BACKGROUND

[0002] Plasma is the liquid part of blood, accounting for about 55% of the volume of whole blood. It is a complex mixture composed of water, proteins, electrolytes, nutrients, hormones and other small molecules dissolved in it. The plasma part of the blood is used for daily blood transfusion. Plasma collection refers to the process of separating plasma from the body of a blood donor through medical technology.

[0003] At present, when plasma collection filtering is carried out through membrane technology, the penetration of plasma is not enough, it is difficult to achieve good separation effect, and part of the plasma is easily carried away with the blood, which reduces the plasma collection effect. And the environmental temperature has a great influence on the quality of the collected plasma. High temperature can easily lead to plasma inactivation. Therefore, a plasma collection system is proposed. SUMMARY

[0004] The purpose of the present application is to solve the problems in the prior art that the penetration of plasma is not enough when filtering with membrane technology, it is difficult to achieve good separation effect, and the plasma collection effect is reduced. And the high temperature of the collection environment can easily lead to plasma inactivation. A plasma collection system is proposed.

[0005] In order to achieve the above purpose, the present application adopts the following technical scheme:

[0006] A plasma collection system, comprising a device box, further comprising: a separation box fixed on the top of the device box, a filter part for separating blood and plasma is arranged in the separation box, wherein a liquid storage ring is arranged on the top of the separation box, and a drop adding part for adding anticoagulant into the separation box is arranged on the liquid storage ring; a refrigerator fixed on the device box, a refrigeration compartment is formed on the side wall of the device box, and the output end of the refrigerator communicates with the inner cavity of the refrigeration compartment, wherein a flow guide part for circulating the cold air flow in the refrigeration compartment is arranged on the device box.

[0007] In order to facilitate blood return, preferably, an installation groove is formed on the top of the device box, a blood collection groove and a plasma collection groove are respectively formed on the upper and lower parts of the side wall of the installation groove, a return pipe is fixedly connected to the bottom of the installation groove, the separation box is inserted and fixed in the installation groove, the input end of the return pipe is inserted into the inner cavity of the separation box, a return pump is fixedly connected to the outer wall of the device box, the return pipe communicates with the return pump, a blood collection tube and a plasma collection tube are respectively fixedly connected to the upper and lower parts of the side wall of the separation box, the blood collection tube and the plasma collection tube respectively penetrate to the outside of the device box along the blood collection groove and the plasma collection groove, and the output end of the plasma collection tube is fixedly connected to a vacuum blood collection bag.

[0008] In order to facilitate plasma separation, preferably, the filtering part includes a filter bucket, which is rotatably connected to the inner cavity of the separation box. The filter bucket is arranged in an inverted "eight" shape, and a filter membrane is fixedly connected to the filtering surface of the filter bucket. The filter bucket and the separation box are fitted and slid, and a filter slurry bin is formed between the filter bucket and the separation box. The input end of the slurry collection tube is connected to the inner cavity of the slurry bin, the output end of the blood collection tube is connected to the upper part of the inner cavity of the separation box, and the input end of the return tube is connected to the inner cavity of the filter bucket.

[0009] In order to improve the efficiency of plasma separation, preferably, the top of the separation box is fixedly connected to a power compartment, the power compartment is communicated with the top of the inner cavity of the separation box, the top of the power compartment is fixedly connected to a drive motor, a rotating shaft is rotatably connected in the power compartment, the top of the rotating shaft is fixedly connected to the output end of the drive motor, a magnetic plate is fixedly connected to the outer wall of the rotating shaft, four groups of piston tubes are fixed at equal intervals on the outer wall of the power compartment, a piston plate is slidably connected in the piston tube, a return spring is fixedly connected between the side wall of the piston plate and the inner wall of the piston tube, the top of the piston tube is fixed and connected to a negative pressure tube, and a one-way valve is provided in the negative pressure tube, the other end of the negative pressure tube is communicated with the inner cavity of the power compartment, and the piston plate and the magnetic plate repel each other magnetically, the end of the piston tube away from the power compartment is communicated with the outside world, and a one-way valve is provided in the channel.

[0010] Furthermore, the rotating shaft extends downward into the cavity of the filter bucket, and the outer wall of the bottom end of the rotating shaft is fixedly connected to the side wall of the filter bucket through a guide rod.

[0011] In order to improve the quality of plasma collection, preferably, the dripping part includes four groups of cross plates, and the four groups of cross plates are fixed at equal intervals on the top of the separation box. The liquid storage ring is fixed on the top of the cross plate, and the liquid storage ring is connected with the inner cavity of the input end of the cross plate. The output end of the cross plate is connected with the top of the inner cavity of the separation box. An intermittent groove is provided in the cross plate, and the intermittent groove is connected with the input end and the output end of the cross plate. A sealing plate is slidably connected in the intermittent groove, and a push rod is fixedly connected to the side wall of the piston plate. The other end of the push rod passes through the piston tube and extends into the intermittent groove and is fixedly connected to the side wall of the sealing plate. A guide groove is provided on the sealing plate.

[0012] Furthermore, the repulsive force between the piston plate and the magnetic plate is greater than the sum of the thrusts required for the retraction of the return spring and the sliding of the blocking plate.

[0013] In order to improve the plasma refrigeration effect, preferably, the guide part includes a guide ring, the guide ring is fixed on four groups of cross plates, and the intermittent groove is connected to the inner cavity of the guide ring, and an air guide pipe is fixed and connected on the outer wall of the guide ring. A circulation bin is opened on the equipment box, and a circulation pipe is fixedly connected to the circulation bin. The input end and the output end of the circulation pipe are both connected to the inner cavity of the refrigeration bin, and a one-way valve is provided in the input end and the output end of the circulation pipe, and the other end of the circulation pipe is connected to the middle inner cavity of the circulation pipe.

[0014] Furthermore, the outer wall of the cold storage compartment is rotatably connected to a sealing cover plate, and a hook is fixedly connected to the side wall of the equipment box. The hook is located above the closed sealing cover plate, and the vacuum blood collection bag is inserted into the hook and fits against the outer wall of the closed sealing cover plate.

[0015] Compared with the prior art, the present invention provides a plasma collection system with the following beneficial effects:

[0016] 1. This plasma collection system continuously reduces the air pressure in the separation box through the repulsive effect of the piston plate and the magnetic plate, allowing the blood to move into the separation box more quickly, effectively improving the blood collection efficiency; and cooperates with the rotating shaft to drive the filter bucket to rotate, thereby generating centrifugal force in the filter bucket, allowing the plasma components in the blood to pass through the filter membrane more quickly and effectively, effectively improving the separation effect.

[0017] 2. In this plasma collection system, when the piston plate and the magnetic plate repel each other, the sealing plate will be pushed to slide in the intermittent groove, so that the guide groove and the inner cavity of the cross plate are connected. At this time, the anticoagulant will drip into the separation box and mix with the blood, effectively preventing the blood from coagulating during the collection process, ensuring the fluidity of the blood, avoiding the blockage of the pipeline, and at the same time preventing the activation of coagulation factors in the blood, thereby improving the blood quality.

[0018] 3. The plasma collection system reduces the temperature in the area where the vacuum blood collection bag is located by setting up a refrigerated chamber and a sealing cover plate, ensuring the quality of plasma collection. In addition, the sealing plate slides back and forth in the intermittent groove, which will cause the cold air flow in the refrigerated chamber to circulate, thereby maintaining a uniform temperature in the refrigerated chamber, improving cooling efficiency and ensuring the preservation quality of the vacuum blood collection bag.

[0019] 4. The plasma collection system, by returning the filtered blood to the donor's body, avoids the anemia symptoms caused by the loss of too many red blood cells, reduces the donor's discomfort, promotes the donor's physical recovery, and ensures the donor's safety. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] Figure 1 Schematic diagram of the overall structure of a plasma collection system proposed by the present invention Figure 1 ;

[0021] Figure 2 Schematic diagram of the overall structure of a plasma collection system proposed by the present invention Figure 2 ;

[0022] Figure 3 Schematic diagram of the overall structure of a plasma collection system proposed by the present invention Figure 3 ;

[0023] Figure 4 This is a side view half-section schematic diagram of the structure of a plasma collection system proposed by the present invention;

[0024] Figure 5 A plasma collection system proposed by the present invention Figure 4 Schematic diagram of the enlarged structure of area A in the middle;

[0025] Figure 6 A plasma collection system proposed by the present invention Figure 4 Schematic diagram of the enlarged structure of the middle B area;

[0026] Figure 7 A plasma collection system proposed by the present invention Figure 4 Schematic diagram of the enlarged structure of the middle C area;

[0027] Figure 8 This is a schematic diagram of the internal structure of the power chamber of a plasma collection system proposed in the present invention.

[0028] In the figure: 1. Equipment box; 2. Separation box; 3. Liquid storage ring; 4. Refrigerator; 41. Refrigeration chamber; 42. Sealing cover; 5. Mounting slot; 51. Blood collection slot; 52. Slurry collection slot; 53. Return pipe; 54. Return pump; 55. Blood collection tube; 56. Slurry collection tube; 57. Vacuum blood collection bag; 6. Filter bucket; 61. Slurry filter chamber; 62. Power chamber; 63. Drive motor; 64. Rotating shaft; 641. Magnetic plate; 642. Guide rod; 65. Piston tube; 651. Piston plate; 652. Return spring; 653. Negative pressure tube; 7. Cross plate; 71. Intermittent slot; 72. Sealing plate; 721. Push rod; 722. Guide slot; 8. Guide ring; 81. Air guide tube; 82. Circulation chamber; 83. Circulation pipe; 9. Hook. DETAILED DESCRIPTION

[0029] The technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all the embodiments.

[0030] In the description of the present invention, it should be understood that the terms "upper", "lower", "front", "back", "left", "right", "top", "bottom", "inside", "outside", etc., indicating directions or positional relationships, are based on the directions or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific direction, be constructed and operated in a specific direction, and therefore should not be understood as limiting the present invention. Example

[0031] Reference Figures 1-8 A plasma collection system includes an equipment box 1, and also includes: a separation box 2 fixed on the top of the equipment box 1, the separation box 2 is provided with a filter part for separating blood and plasma, wherein a liquid storage ring 3 is provided on the top of the separation box 2, and a dripping part for adding an anticoagulant to the separation box 2 is provided on the liquid storage ring 3; a refrigerator 4 fixed on the equipment box 1, the refrigerator 4 adopts existing mature technology, a refrigeration compartment 41 is opened on the side wall of the equipment box 1, and the output end of the refrigerator 4 is connected to the inner cavity of the refrigeration compartment 41, wherein the equipment box 1 is provided with a guide part for promoting the circulation of cold air in the refrigeration compartment 41.

[0032] Reference Figures 1-4 , wherein, a mounting slot 5 is provided on the top of the equipment box 1, and a blood collection slot 51 and a plasma collection slot 52 are provided on the upper and lower parts of the side walls of the mounting slot 5 respectively. A return pipe 53 is fixedly connected to the bottom of the mounting slot 5. The separation box 2 is plugged and fixed in the mounting slot 5, and the input end of the return pipe 53 is plugged into the bottom of the inner cavity of the separation box 2. A return pump 54 is fixedly connected to the outer wall of the equipment box 1, and the return pipe 53 is connected to the return pump 54. A blood collection tube 55 and a plasma collection tube 56 are fixedly connected to the upper and lower parts of the side walls of the separation box 2 respectively. The blood collection tube 55 and the plasma collection tube 56 pass through the blood collection slot 51 and the plasma collection slot 52 respectively to the outside of the equipment box 1, and the output end of the plasma collection tube 56 is fixedly connected to a vacuum blood collection bag 57.

[0033] It should be noted that the ends of the blood collection tube 55 and the return tube 53 can be detachably connected to existing disposable blood collection needles to improve the convenience of use.

[0034] Through the arrangement of the above structure, the blood collection tube 55 and the return tube 53 are connected to the blood collection needle and inserted into the blood vessel of the blood donor: the disposable blood collection needle is installed at the ends of the blood collection tube 55 and the return tube 53, and the blood collection needle at the end of the blood collection tube 55 is first inserted into the blood vessel of the blood donor. Under the action of blood pressure, the blood will flow into the separation box 2 along the blood collection tube 55; at the same time, the return pump 54 is turned on to extract the blood. After the residual air in the return tube 53 is emptied, the blood collection needle at the end of the return tube 53 is inserted into the blood vessel of the blood donor, so that the blood is returned to the body of the blood donor, avoiding the anemia symptoms caused by the loss of too many red blood cells, reducing the discomfort of the blood donor, promoting the physical recovery of the blood donor, and ensuring the safety of the blood donor.

[0035] Reference Figure 4 、 Figure 5 、 Figure 7 and Figure 8 , wherein the filtering part includes a filter bucket 6, which is rotatably connected to the inner cavity of the separation box 2. The filter bucket 6 is arranged in an inverted "eight" shape, and a filter membrane is fixedly connected to the filtering surface of the filter bucket 6. The filter bucket 6 slides in contact with the separation box 2, and a filter pulp bin 61 is formed between the filter bucket 6 and the separation box 2. The input end of the slurry collection tube 56 is connected to the inner cavity of the filter pulp bin 61, the output end of the blood collection tube 55 is connected to the upper part of the inner cavity of the separation box 2, and the input end of the return tube 53 is connected to the inner cavity of the filter bucket 6; the top of the separation box 2 is fixedly connected to the power bin 62, and the power bin 62 is connected to the top of the inner cavity of the separation box 2. The top of the power bin 62 is fixedly connected to the drive motor 63, and a rotating shaft 64 is rotatably connected in the power bin 62. The top of the rotating shaft 64 is fixedly connected to the output end of the drive motor 63 Then, a magnetic plate 641 is fixedly connected to the outer wall of the rotating shaft 64, and four groups of piston tubes 65 are fixed at equal intervals on the outer wall of the power chamber 62. A piston plate 651 is slidably connected inside the piston tube 65, and a return spring 652 is fixedly connected between the side wall of the piston plate 651 and the inner wall of the piston tube 65. The top of the piston tube 65 is fixed and connected to a negative pressure tube 653, and a one-way valve is provided in the negative pressure tube 653. The other end of the negative pressure tube 653 is connected to the inner cavity of the power chamber 62, and the piston plate 651 and the magnetic plate 641 repel each other magnetically. The end of the piston tube 65 away from the power chamber 62 is connected to the outside world, and a one-way valve is provided in the channel; the rotating shaft 64 extends downward into the cavity of the filter bucket 6, and the outer wall of the bottom end of the rotating shaft 64 is fixedly connected to the side wall of the filter bucket 6 through the guide rod 642.

[0036] It should be noted that the one-way valve at the inner and outer connection of the piston tube 65 can only discharge the gas in the piston tube 65; the one-way valve in the negative pressure tube 653 can only allow the gas in the separation box 2 to be sucked into the piston tube 65.

[0037] By setting the above structure, the driving motor 63 is turned on to drive the rotating shaft 64 to rotate, so that the piston plate 651 and the magnetic plate 641 move to the repulsive area. Under the repulsive action of the two, the piston plate 651 will be pushed to slide in the piston tube 65, thereby compressing the gas in the piston tube 65 and opening the one-way valve connected to the outside of the piston tube 65, so that the gas in the piston tube 65 is discharged. Then the piston plate 651 and the magnetic plate 641 are separated from the repulsive area. At this time, under the rebound action of the reset spring 652, the piston plate 651 will be reset, thereby generating suction in the piston tube 65 and opening the one-way valve in the negative pressure tube 653. The gas in the separation box 2 is sucked out, thereby reducing the air pressure in the separation box 2, causing the blood to move more quickly into the separation box 2, effectively improving the blood collection efficiency; and when the blood enters the separation box 2, it will fall onto the filter bucket 6, and then slide down along the filter bucket 6. In this process, the plasma part of the blood with better particle size will pass through the filter membrane and enter the filter slurry bin 61, and then flow along the slurry collection tube 56 to the vacuum blood collection bag 57, and the rotating shaft 64 will also drive the filter bucket 6 to rotate at a low speed in the separation box 2. At this time, centrifugal force will be generated, causing the plasma components in the blood to pass through the filter membrane more quickly and effectively, effectively improving the separation effect.

[0038] Reference Figure 1 、 Figure 4 and Figure 6 , wherein the dripping part includes four groups of cross plates 7, which are fixed at equal intervals on the top of the separation box 2, and the liquid storage ring 3 is fixed on the top of the cross plate 7. The liquid storage ring 3 is communicated with the inner cavity of the input end of the cross plate 7, and the output end of the cross plate 7 is communicated with the top of the inner cavity of the separation box 2. An intermittent groove 71 is provided in the cross plate 7, and the intermittent groove 71 is communicated with the input end and the output end of the cross plate 7. A sealing plate 72 is slidably connected in the intermittent groove 71, and a push rod 721 is fixedly connected to the side wall of the piston plate 651. The other end of the push rod 721 passes through the piston tube 65 and extends into the intermittent groove 71 and is fixedly connected to the side wall of the sealing plate 72. A guide groove 722 is provided on the sealing plate 72; the repulsive force between the piston plate 651 and the magnetic plate 641 is greater than the sum of the thrust required for the retraction of the reset spring 652 and the sliding of the sealing plate 72.

[0039] Through the setting of the above structure, when the piston plate 651 and the magnetic plate 641 repel each other, the piston plate 651 will also push the sealing plate 72 to slide in the intermittent groove 71 through the push rod 721, so that the guide groove 722 is connected with the input end and the output end of the cross plate 7. At this time, the anticoagulant in the liquid storage ring 3 will drip into the separation box 2 and mix with the blood, effectively avoiding the coagulation of blood during the collection process, ensuring the fluidity of the blood, avoiding the blockage of the pipeline, and at the same time preventing the activation of coagulation factors in the blood, thereby improving the blood quality.

[0040] Reference Figures 1-4 , wherein the guide part includes a guide ring 8, which is fixed on the four groups of cross plates 7, and the intermittent groove 71 is connected to the inner cavity of the guide ring 8, and an air guide pipe 81 is fixed on the outer wall of the guide ring 8 and is connected. A circulation warehouse 82 is opened on the equipment box 1, and a circulation pipe 83 is fixedly connected to the circulation warehouse 82. The input end and output end of the circulation pipe 83 are both connected to the inner cavity of the cold storage warehouse 41, and a one-way valve is provided in the input end and output end of the circulation pipe 83. The other end of the circulation pipe 83 is connected to the middle inner cavity of the circulation pipe 83; the outer wall of the cold storage warehouse 41 is rotatably connected to the sealing cover plate 42, and the sealing cover plate 42 is made of metal and has a certain ability to conduct temperature. A hook 9 is fixedly connected to the side wall of the equipment box 1, and the hook 9 is located above the closed sealing cover plate 42. The vacuum blood collection bag 57 is inserted into the hook 9 and fits against the outer wall of the closed sealing cover plate 42.

[0041] Through the arrangement of the above structure, the vacuum blood collection bag 57 is plugged into the hook 9 so that it fits with the outer wall of the sealing cover 42. At this time, the refrigerator 4 is turned on to cool the cold storage chamber 41, and the cooling effect in the cold storage chamber 41 will reduce the temperature around the sealing cover 42, thereby ensuring the quality of plasma collection. When the plasma collection is completed, the vacuum blood collection bag 57 is removed and placed in the cold storage chamber 41, and a new vacuum blood collection bag 57 is replaced to continue the blood collection operation, which makes it easier for the vacuum blood collection bag 57 to be refrigerated and improves the convenience of plasma collection. When the sealing plate 72 is pushed to slide in the intermittent groove 71, the intermittent groove 71 will be squeezed. The gas enters the guide ring 8 and moves along the air guide pipe 81 to the circulation pipe 83, and opens the one-way valve at the output end of the circulation pipe 83, allowing the gas to enter the cold storage chamber 41. Subsequently, the sealing plate 72 is pulled back to its original position, which will generate suction in the intermittent groove 71 and transmit it to the circulation pipe 83, so that the one-way valve at the input end of the circulation pipe 83 opens, allowing the airflow in the cold storage chamber 41 to enter the circulation pipe 83. This reciprocating process will cause the cold airflow in the cold storage chamber 41 to circulate, thereby maintaining the uniform temperature in the cold storage chamber 41, improving the cooling efficiency, and ensuring the preservation quality of the vacuum blood collection bag 57.

[0042] Reference Figures 1-8In the present invention, when in use, the disposable blood collection needle is installed at the end of the blood collection tube 55 and the return tube 53. First, the blood collection needle at the end of the blood collection tube 55 is inserted into the blood vessel of the blood donor. Under the action of blood pressure, the blood will flow into the separation box 2 along the blood collection tube 55. At the same time, the driving motor 63 is turned on to drive the rotating shaft 64 to rotate, so that the piston plate 651 and the magnetic plate 641 move to the repulsive area. Under the repulsive action of the two, the piston plate 651 will be pushed to slide in the piston tube 65, thereby compressing the gas in the piston tube 65 and opening the one-way valve connected to the outside of the piston tube 65, so that the gas in the piston tube 65 is discharged. Then the piston plate 651 and the magnetic plate 641 will be separated from the repulsive area. At this time, under the rebound action of the return spring 652, the piston plate 6 51 is reset, thereby generating suction in the piston tube 65, and opening the one-way valve in the negative pressure tube 653, so that the gas in the separation box 2 is sucked out, thereby reducing the air pressure in the separation box 2, and causing the blood to move more quickly into the separation box 2, effectively improving the blood collection efficiency; and when the blood enters the separation box 2, it will fall onto the filter bucket 6, and then slide down the filter bucket 6. In this process, the plasma part of the blood with a better particle size will pass through the filter membrane and enter the filter slurry bin 61, and then flow along the slurry collection tube 56 to the vacuum blood collection bag 57, and the rotating shaft 64 will also drive the filter bucket 6 to rotate at a low speed in the separation box 2. At this time, centrifugal force will be generated, causing the plasma components in the blood to pass through the filter membrane more quickly and effectively, effectively improving the separation effect. The blood from which the plasma has been filtered out will then flow along the filter bucket 6 into the return tube 53. At this time, the return pump 54 is turned on to extract the blood. After the remaining air in the return tube 53 is emptied, the blood collection needle at the end of the return tube 53 is inserted into the blood vessel of the blood donor, so that the blood is returned to the blood donor's body, avoiding the blood donor's anemia symptoms due to the loss of too many red blood cells, reducing the blood donor's discomfort, promoting the blood donor's physical recovery, and ensuring the blood donor's safety.

[0043] When the piston plate 651 and the magnetic plate 641 repel each other, the piston plate 651 will also push the sealing plate 72 to slide in the intermittent groove 71 through the push rod 721, so that the guide groove 722 is connected with the input end and the output end of the cross plate 7. At this time, the anticoagulant in the liquid storage ring 3 will drip into the separation box 2 and mix with the blood, effectively avoiding the coagulation of blood during the collection process, ensuring the fluidity of the blood, avoiding the blockage of the pipeline, and at the same time preventing the activation of coagulation factors in the blood, improving the blood quality, and under the rotation of the filter bucket 6, it is fully mixed with the blood, effectively improving the mixing effect.

[0044] When collecting plasma, the vacuum blood collection bag 57 is plugged into the hook 9 so that it fits with the outer wall of the sealing cover 42. At this time, the refrigerator 4 is turned on to cool the cold storage chamber 41. The cooling effect in the cold storage chamber 41 will reduce the temperature around the sealing cover 42, thereby ensuring the quality of plasma collection. When the plasma collection is completed, the vacuum blood collection bag 57 is removed and placed in the cold storage chamber 41, and a new vacuum blood collection bag 57 is replaced to continue the blood collection operation, which makes it easier for the vacuum blood collection bag 57 to be refrigerated and improves the convenience of plasma collection. When the sealing plate 72 is pushed to slide in the intermittent groove 71, the intermittent groove 71 will be squeezed. The gas enters the guide ring 8 and moves along the air guide pipe 81 to the circulation pipe 83, and opens the one-way valve at the output end of the circulation pipe 83, allowing the gas to enter the cold storage chamber 41. Subsequently, the sealing plate 72 is pulled back to its original position, which will generate suction in the intermittent groove 71 and transmit it to the circulation pipe 83, so that the one-way valve at the input end of the circulation pipe 83 opens, allowing the airflow in the cold storage chamber 41 to enter the circulation pipe 83. This reciprocating process will cause the cold airflow in the cold storage chamber 41 to circulate, thereby maintaining the uniform temperature in the cold storage chamber 41, improving the cooling efficiency, and ensuring the preservation quality of the vacuum blood collection bag 57. Example

[0045] Reference Figures 1-8 , which is basically the same as Example 1. On the basis of Example 1, a plasma collection method is proposed, and the steps are as follows:

[0046] Step 1. Connect the blood collection tube 55 and the return tube 53 to the blood collection needle and insert them into the blood donor's blood vessel: Install the disposable blood collection needle at the end of the blood collection tube 55 and the return tube 53. First, insert the blood collection needle at the end of the blood collection tube 55 into the blood donor's blood vessel. Under the action of blood pressure, the blood will flow along the blood collection tube 55 into the separation box 2, and the plasma in the blood will pass through the filter membrane into the filter slurry chamber 61. At this time, turn on the return pump 54 to extract the blood. After the residual air in the return tube 53 is emptied, insert the blood collection needle at the end of the return tube 53 into the blood donor's blood vessel, so that the blood is returned to the blood donor's body, avoiding anemia symptoms caused by the loss of too many red blood cells, reducing the blood donor's discomfort, promoting the blood donor's physical recovery, and ensuring the safety of the blood donor.

[0047] Step 2: Collect the blood into the separation box 2 for separation and collection: Turn on the driving motor 63 to drive the rotating shaft 64 to rotate, so that the piston plate 651 and the magnetic plate 641 move to the repulsive area. Under the repulsive action of the two, the piston plate 651 will be pushed to slide in the piston tube 65, thereby compressing the gas in the piston tube 65 and opening the one-way valve connected to the outside of the piston tube 65, so that the gas in the piston tube 65 is discharged. Then the piston plate 651 and the magnetic plate 641 are separated from the repulsive area. At this time, under the rebound action of the reset spring 652, the piston plate 651 will be reset, thereby generating suction in the piston tube 65 and making the one-way valve in the negative pressure tube 653 The valve opens, causing the gas in the separation box 2 to be sucked out, thereby reducing the air pressure in the separation box 2 and causing the blood to move more quickly into the separation box 2, effectively improving the blood collection efficiency; and when the blood enters the separation box 2, it will fall onto the filter bucket 6, and then slide down the filter bucket 6. During this process, the plasma part of the blood with a better particle size will pass through the filter membrane and enter the filter slurry chamber 61, and then flow along the slurry collection tube 56 to the vacuum blood collection bag 57, and the rotating shaft 64 will also drive the filter bucket 6 to rotate at a low speed in the separation box 2. At this time, centrifugal force will be generated, causing the plasma components in the blood to pass through the filter membrane more quickly and effectively, effectively improving the separation effect.

[0048] Step 3. Add anticoagulant to the blood entering the separation box 2: When the piston plate 651 and the magnetic plate 641 repel each other, the piston plate 651 will also push the sealing plate 72 to slide in the intermittent groove 71 through the push rod 721, so that the guide groove 722 is connected with the input and output ends of the cross plate 7. At this time, the anticoagulant in the liquid storage ring 3 will drip into the separation box 2 and mix with the blood, effectively avoiding the coagulation of blood during the collection process, ensuring the fluidity of the blood, avoiding blockage of the pipeline, and at the same time preventing the activation of coagulation factors in the blood, thereby improving the blood quality.

[0049] Step 4: refrigerate the collected plasma: After the plasma collection is completed, the vacuum blood collection bag 57 is removed and placed in the cold storage chamber 41, and a new vacuum blood collection bag 57 is replaced to continue the blood collection operation, which facilitates the refrigeration of the vacuum blood collection bag 57 and improves the convenience of plasma collection; and when the blocking plate 72 is pushed to slide in the intermittent groove 71, the gas in the intermittent groove 71 will be squeezed, and the gas will enter the guide ring 8, move along the air guide pipe 81 to the circulation pipe 83, and open the one-way valve at the output end of the circulation pipe 83, so that the gas enters the cold storage chamber 41, and then the blocking plate 72 is pulled back to its original position, which will generate suction in the intermittent groove 71 and transmit it to the circulation pipe 83, so that the one-way valve at the input end of the circulation pipe 83 is opened, so that the air flow in the cold storage chamber 41 enters the circulation pipe 83, and so on. This will make the cold air flow in the cold storage chamber 41 circulate, which can maintain the uniform temperature in the cold storage chamber 41, improve the cooling efficiency and ensure the preservation quality of the vacuum blood collection bag 57.

[0050] The above description is only a preferred specific embodiment of the present invention, but the scope of protection of the present invention is not limited thereto. Any technician familiar with the technical field, within the technical scope disclosed by the present invention, who makes equivalent replacements or changes based on the technical solution and inventive concept of the present invention, should be covered by the scope of protection of the present invention.

Claims

1. A plasma collection system, comprising an equipment box (1), characterized in that: Also includes: A separation box (2) is fixed on the top of the equipment box (1), wherein a filter part for separating blood and plasma is provided in the separation box (2). Wherein, a liquid storage ring (3) is provided on the top of the separation box (2), and a dripping portion for adding an anticoagulant into the separation box (2) is provided on the liquid storage ring (3); A refrigerator (4) is fixed on the equipment box (1), a refrigeration chamber (41) is provided on the side wall of the equipment box (1), and the output end of the refrigerator (4) is communicated with the inner cavity of the refrigeration chamber (41). The equipment box (1) is provided with a guide portion for promoting the circulation of cold air in the refrigerated compartment (41); The top of the equipment box (1) is provided with a mounting groove (5), and the upper and lower parts of the side walls of the mounting groove (5) are respectively provided with a blood collection groove (51) and a pulp collection groove (52), and the bottom of the mounting groove (5) is fixedly connected with a return pipe (53), the separation box (2) is plugged and fixed in the mounting groove (5), and the input end of the return pipe (53) is plugged into the bottom of the inner cavity of the separation box (2), and a return pump (54) is fixedly connected to the outer wall of the equipment box (1), and the return pipe (53) is connected to the return pump (54), and the upper and lower parts of the side walls of the separation box (2) are respectively fixedly connected with a blood collection blood tube (55) and a pulp collection blood tube (56), and the blood collection blood tube (55) and the pulp collection blood tube (56) respectively pass through the blood collection groove (51) and the pulp collection groove (52) to the outside of the equipment box (1), and the output end of the pulp collection blood tube (56) is fixedly connected with a vacuum blood collection bag (57); The filtering portion comprises a filter hopper (6), the filter hopper (6) being rotatably connected to the inner cavity of the separation box (2), the filter hopper (6) being arranged in an inverted "eight" shape, and a filter membrane being fixedly connected to the filtering surface of the filter hopper (6), the filter hopper (6) slidingly fitting with the separation box (2), and a filter slurry bin (61) being formed between the filter hopper (6) and the separation box (2), the input end of the slurry collection tube (56) being in communication with the inner cavity of the filter slurry bin (61), the output end of the blood collection tube (55) being in communication with the upper inner cavity of the separation box (2), and the input end of the return tube (53) being in communication with the inner cavity of the filter hopper (6); The top of the separation box (2) is fixedly connected to a power bin (62), the power bin (62) is communicated with the top of the inner cavity of the separation box (2), the top of the power bin (62) is fixedly connected to a drive motor (63), a rotating shaft (64) is rotatably connected in the power bin (62), the top of the rotating shaft (64) is fixedly connected to the output end of the drive motor (63), a magnetic plate (641) is fixedly connected to the outer wall of the rotating shaft (64), four groups of piston tubes (65) are fixed at equal intervals on the outer wall of the power bin (62), and the piston tubes (65) are fixedly connected to the outer wall of the power bin (62). A piston plate (651) is slidably connected, and a return spring (652) is fixedly connected between the side wall of the piston plate (651) and the inner wall of the piston tube (65). The top of the piston tube (65) is fixed and connected to a negative pressure tube (653), and a one-way valve is provided in the negative pressure tube (653). The other end of the negative pressure tube (653) is connected to the inner cavity of the power chamber (62), and the piston plate (651) and the magnetic plate (641) repel each other magnetically. The end of the piston tube (65) away from the power chamber (62) is connected to the outside world, and a one-way valve is provided in the channel.

2. A plasma collection system according to claim 1, characterized in that: The rotating shaft (64) extends downward into the cavity of the filter bucket (6), and the outer wall of the bottom end of the rotating shaft (64) is fixedly connected to the side wall of the filter bucket (6) via a guide rod (642).

3. A plasma collection system according to claim 1, characterized in that: The dripping part includes four groups of cross plates (7), and the four groups of cross plates (7) are fixed on the top of the separation box (2) at equal intervals. The liquid storage ring (3) is fixed on the top of the cross plate (7), and the liquid storage ring (3) is communicated with the inner cavity of the input end of the cross plate (7). The output end of the cross plate (7) is communicated with the top of the inner cavity of the separation box (2). An intermittent groove (71) is provided in the cross plate (7), and the intermittent groove (71) is communicated with the input end and the output end of the cross plate (7). A sealing plate (72) is slidably connected in the intermittent groove (71). A push rod (721) is fixedly connected to the side wall of the piston plate (651), and the other end of the push rod (721) passes through the piston tube (65) and extends into the intermittent groove (71) and is fixedly connected to the side wall of the sealing plate (72). A guide groove (722) is provided on the sealing plate (72).

4. A plasma collection system according to claim 3, characterized in that: The repulsive force between the piston plate (651) and the magnetic plate (641) is greater than the sum of the thrusts required for the retraction of the return spring (652) and the sliding of the blocking plate (72).

5. A plasma collection system according to claim 3, characterized in that: The guide portion includes a guide ring (8), the guide ring (8) is fixed on the four groups of cross plates (7), and the intermittent groove (71) is connected to the inner cavity of the guide ring (8), and an air guide pipe (81) is fixed and connected to the outer wall of the guide ring (8). A circulation bin (82) is opened on the equipment box (1), and a circulation pipe (83) is fixedly connected to the circulation bin (82). The input end and the output end of the circulation pipe (83) are both connected to the inner cavity of the cold storage bin (41), and a one-way valve is provided in the input end and the output end of the circulation pipe (83). The other end of the circulation pipe (83) is connected to the middle inner cavity of the circulation pipe (83).

6. A plasma collection system according to claim 5, characterized in that: The outer wall of the cold storage chamber (41) is rotatably connected to a sealing cover (42), and a hook (9) is fixedly connected to the side wall of the equipment box (1). The hook (9) is located above the closed sealing cover (42), and the vacuum blood collection bag (57) is inserted into the hook (9) and fits with the outer wall of the closed sealing cover (42).

Images