Pure traditional Chinese medicine for treating acute and chronic liver diseases and preparation method thereof

Through precise proportion of traditional Chinese medicinal materials and modern preparation technology, a pure Chinese medicine for treating acute and chronic liver diseases is prepared, which solves the side effects and stability problems of the treatment methods in the prior art, and achieves a more efficient and safer therapeutic effect.

CN119656275AInactive Publication Date: 2025-03-21SHANGHAI DADAOHE BIOMEDICAL RES CO LTD
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Patent Information

Application Number
CN202411947923.8
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-12-27
Publication Date
2025-03-21
Estimated Expiration
Not applicable · inactive patent

AI Technical Summary

Technical Problem

In the prior art, when treating acute and chronic liver diseases, Western medicine treatment has side effects and viral resistance problems, while the degree of extraction and purification of the drug-effective ingredients of traditional Chinese medicine treatment is limited, which limits the stability and performance of the therapeutic effect.

Method used

Through precise proportion of Chinese medicinal materials and modern preparation technology, a pure Chinese medicine agent including a variety of Chinese medicine components is prepared, and a thick paste-like medicine is prepared by spray drying technology to improve the efficacy and reduce side effects.

Benefits of technology

It improves the efficacy and safety of the drug, simplifies the preparation process of traditional Chinese medicine, and improves the extraction and purification of the effective ingredients, making the drug more stable and easy to absorb, and reduces the side effects of the drug.

✦ Generated by Eureka AI based on patent content.

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Abstract

The invention discloses a pure traditional Chinese medicine for treating acute and chronic liver diseases and a preparation method thereof, and belongs to the technical field of liver disease treatment. The pure traditional Chinese medicine preparation comprises the following components in parts by weight: 1-10 parts of vinegar tortoise plastron, 1-5 parts of American ginseng, 1-6 parts of Sichuan yellow, 1-3 parts of donkey-hide gelatin, 1-4 parts of cordyceps sinensis, 1-5 parts of lucid ganoderma, 1-4 parts of prinsepia utilis royle, 1-3 parts of olean, 1-4 parts of cedar parasitism, 1-3 parts of parasitic loranthus, 1-5 parts of grifola, 1-4 parts of couch grass root, 0.5-3 parts of saffron crocus, 1-4 parts of angelica sinensis, 1-4 parts of polygonum cuspidatum, 1-5 parts of penthorum chinense pursh, 0.5-3 parts of calculus bovis factitius and 1-4 parts of radix paeoniae alba. The traditional Chinese medicine composition is prepared from 1-3 parts of oregano, 1-4 parts of fructus lycii, 1-3 parts of schisandra chinensis, 1-4 parts of fructus gardeniae, 1-4 parts of artemisia capillaris, 1-3 parts of dandelion, 1-3 parts of safflower, 1-4 parts of abrus herb, 1-3 parts of selfheal, 1-3 parts of verbena, 1-3 parts of fennel, 1-3 parts of tangerine seed and 1-4 parts of liquorice. According to the invention, through accurate component proportion, the optimal combination of the medicinal components is ensured, the curative effect and safety of the medicine are improved, the preparation process of the traditional Chinese medicine is simplified, and the extraction and purification degree of the medicinal components is improved.
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Description

Technical Field

[0001] The invention belongs to the technical field of liver disease treatment, and in particular relates to a pure Chinese medicine for treating acute and chronic liver diseases and a preparation method thereof. Background Art

[0002] Acute and chronic liver diseases are a type of disease that seriously affects human health, and the current status of their treatment involves a variety of methods. In terms of Western medicine treatment, antiviral treatment, alcohol abstinence treatment, surgical treatment, and chemotherapy are mainly used. For chronic liver disease, especially chronic hepatitis B, antiviral drugs are closely related to the treatment of chronic viral hepatitis. In addition, for non-alcoholic fatty liver disease (NAFLD) / non-alcoholic steatohepatitis (NASH), current and future drug treatment research is also underway. In terms of traditional Chinese medicine treatment, the method of traditional Chinese medicine for treating liver disease is derived from regulating liver function, including storing blood and regulating the smooth flow of qi, involving modern functional systems such as digestion, endocrine, and gut-liver axis, and is based on modern liver physiology, pathology, and etiology. Traditional Chinese medicine combined with antiviral treatment can improve the clinical outcome of chronic hepatitis B and help HBV carriers prevent disease progression. Comprehensive Chinese and Western medicine can block the deterioration caused by endotoxins for acute-chronic liver failure. Traditional Chinese medicine has been widely used in protecting the liver, nonspecific anti-inflammatory, alleviating liver fibrosis, and preventing non-alcoholic fatty liver.

[0003] In the existing technology, the methods for treating acute and chronic liver diseases mainly include Western medicine and traditional Chinese medicine. Western medicine treatment usually relies on antiviral drugs and immunomodulators, but these treatments may bring certain side effects, and long-term use may lead to increased viral resistance. On the other hand, traditional Chinese medicine treatment focuses on adjusting the overall balance of the body through the use of Chinese herbal medicines, but its preparation method is complicated, and the extraction and purification of active ingredients are limited, which limits the stability and performance of the treatment effect. Summary of the invention

[0004] In view of the above situation, in order to overcome the defects of the prior art, the present invention achieves the purpose of improving the efficacy and reducing the side effects through precise proportion of Chinese medicinal materials and modern preparation technology.

[0005] In order to achieve the above object, the following technical scheme is adopted: The present invention provides a pure Chinese medicine for treating acute and chronic liver diseases, comprising the following components in parts by weight:

[0006] 1-10 parts of tortoise shell with vinegar, 1-5 parts of American ginseng, 1-6 parts of Sichuan yellow, 1-3 parts of donkey-hide gelatin, 1-4 parts of cordyceps, 1-5 parts of ganoderma lucidum, 1-4 parts of pricking fruit, 1-3 parts of olea truncatum, 1-4 parts of cedar parasitic, 1-3 parts of mistletoe, 1-5 parts of umbellate, 1-4 parts of imperata rhizome, 0.5-3 parts of saffron, 1-4 parts of angelica, 1-4 parts of knotweed, 1-5 parts of radix strychnifoliae, 0.5-3 parts of artificial bezoar, 1-4 parts of white peony root, 1-3 parts of oregano, 1-4 parts of wolfberry, 1-3 parts of schisandra chinensis, 1-4 parts of gardenia, 1-4 parts of artemisia capillaris, 1-3 parts of dandelion, 1-3 parts of safflower, 1-4 parts of schisandra chinensis, 1-3 parts of vervain, 1-3 parts of fennel, 1-3 parts of orange seed and 1-4 parts of liquorice.

[0007] Preferably, the pure Chinese medicine comprises the following components in parts by weight:

[0008] 1-5 parts of tortoise shell with vinegar, 1-3 parts of American ginseng, 1-4 parts of Sichuan yellow, 1-2 parts of donkey-hide gelatin, 1-3 parts of cordyceps, 1-4 parts of ganoderma lucidum, 1-3 parts of pricking fruit, 1-2 parts of olea truncatum, 1-3 parts of cedar parasitic, 1-2 parts of mistletoe, 1-4 parts of umbellate, 1-3 parts of imperata root, 0.5-2 parts of saffron, 1-3 parts of angelica, 1-3 parts of knotweed, 1-4 parts of radix strychnifoliae, 0.5-2 parts of artificial bezoar, 1-3 parts of white peony root, 1-2 parts of oregano, 1-3 parts of wolfberry, 1-2 parts of schisandra, 1-3 parts of gardenia, 1-3 parts of artemisia capillaris, 1-2 parts of dandelion, 1-2 parts of safflower, 1-3 parts of schisandra, 1-2 parts of fennel, 1-2 parts of orange seed and 1-3 parts of licorice.

[0009] Preferably, the pure Chinese medicine comprises the following components in parts by weight:

[0010] 2-4 parts of tortoise shell with vinegar, 2-3 parts of American ginseng, 2-3 parts of Sichuan huang, 1-1.5 parts of donkey hide gelatin, 2-2.5 parts of cordyceps, 2-3 parts of ganoderma lucidum, 2-2.5 parts of prickle fruit, 1.5-1.8 parts of olea truncatum, 2-2.5 parts of cedar parasitic, 1.5-1.8 parts of mistletoe, 2-3 parts of umbellate, 2-2.5 parts of imperata root, 1-1.5 parts of saffron, 2-2.5 parts of angelica, 2-2.5 parts of knotweed, 2-2.5 parts of radix polygoni cuspidatis, 2-3 parts of radix scutellariae, 1-1 .5 parts, white peony 2-2.5 parts, oregano 1.5-1.8 parts, wolfberry 2-2.5 parts, Schisandra 1.5-1.8 parts, gardenia 2-2.5 parts, Artemisia capillaris 2-2.5 parts, dandelion 1.5-1.8 parts, safflower 1.5-1.8 parts, chicken bone grass 2-2.5 parts, selfheal 1.5-1.8 parts, verbena 1.5-1.8 parts, fennel 1.5-1.8 parts, orange seed 1.5-1.8 parts and licorice 2-2.5 parts.

[0011] As the most preferred embodiment, the pure Chinese medicine comprises the following components in parts by weight:

[0012] 3 parts of tortoise shell with vinegar, 2.5 parts of American ginseng, 2.5 parts of Sichuan rhubarb, 1.2 parts of donkey-hide gelatin, 2.2 parts of cordyceps, 2.5 parts of ganoderma lucidum, 2.2 parts of pricking fruit, 1.6 parts of olea truncatum, 2.2 parts of cedar parasitic, 1.6 parts of mistletoe, 2.5 parts of umbellate, 2.2 parts of imperata rhizome, 1.2 parts of saffron, 2.2 parts of angelica, 2.2 parts of knotweed, 2.5 parts of radix strychnifoliae, 1.2 parts of artificial bezoars, 2.2 parts of white peony root, 1.6 parts of oregano, 2.2 parts of wolfberry, 1.6 parts of schisandra chinensis, 2.2 parts of gardenia, 2.2 parts of artemisia capillaris, 1.6 parts of dandelion, 1.6 parts of safflower, 2.2 parts of safflower, 1.6 parts of smilax china, 1.6 parts of selfheal, 1.6 parts of verbena, 1.6 parts of fennel, 1.6 parts of tangerine seed and 2.2 parts of liquorice.

[0013] The present invention also provides a method for preparing a pure Chinese medicine for treating acute and chronic liver diseases, comprising the following steps:

[0014] a. Accurately weigh the above parts by weight of tortoise shell, American ginseng, Sichuan yellow, donkey-hide gelatin, cordyceps, Ganoderma lucidum, prickle fruit, Olea europaea, parasitic cedar, mistletoe, Polyporus, Imperata root, saffron, angelica, knotweed, root vegetable, artificial bezoar, white peony, oregano, wolfberry, Schisandra chinensis, gardenia, Artemisia capillaris, dandelion, safflower, chicken bone grass, selfheal, verbena, fennel, orange seed, licorice;

[0015] b. Wash the tortoise shell with vinegar, American ginseng, donkey-hide gelatin, cordyceps, ganoderma lucidum, prickle fruit, olea, fir parasitic, mistletoe, umbellate, Imperata root, artificial bezoar, white peony, oregano, wolfberry, Schisandra chinensis, gardenia, orange seed, licorice with pure water to remove dust and impurities on the surface, and then dry them naturally under well-ventilated conditions and then grind them separately until the herbs reach a fineness of more than 200 mesh and set aside;

[0016] c. The saffron, angelica, knotweed, root vegetable, Artemisia capillaris, dandelion, safflower, chicken bone grass, selfheal, verbena, fennel, such herbs need to be washed with purified water or distilled water, dried naturally and crushed to a fineness of more than 200 mesh, add 8-10 times the mass of distilled water, soak for 5-6h, after the soaking is completed, first boil with high heat, then turn to low heat and keep it in a slightly boiling state for 1-2h, filter, collect the filtrate, add 6-8 times the mass of distilled water to the residue, repeat the above decoction and filtration operation, combine the two filtrates, and set aside;

[0017] d. The powder of step b and the filtrate of step c are mixed evenly, and then concentrated under reduced pressure at 60-70°C until it is concentrated to a thick paste with a relative density of 1.2-1.3, and the pure Chinese medicine is prepared by spray drying.

[0018] Furthermore, the spray drying parameters are: air inlet temperature: 160-180°C, air outlet temperature: 70-90°C, atomizer speed: 10000-15000rpm.

[0019] Furthermore, the pure Chinese medicine is one of pills, capsules, granules and powders.

[0020] Furthermore, the pure Chinese medicine is preferably an granule.

[0021] The beneficial effects of the present invention are as follows: the present invention ensures the optimal combination of medicinal ingredients through precise component ratio, improves the efficacy and safety of the medicine, the preparation method of the present invention simplifies the preparation process of traditional Chinese medicine, improves the extraction and purification degree of medicinal ingredients, makes the medicine more stable and easy to absorb, the pure Chinese medicine of the present invention helps to improve the liver function of patients with acute and chronic liver diseases, alleviate symptoms, and improve the quality of life. Compared with Western medicine treatment, the pure Chinese medicine of the present invention reduces the side effects of the medicine and is more suitable for long-term use. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] Figure 1 This is the efficacy evaluation result of a pure Chinese medicine for treating acute and chronic liver diseases of the present invention.

[0023] The accompanying drawings are used to provide further understanding of the present invention and constitute a part of the specification. They are used to explain the present invention together with the embodiments of the present invention and do not constitute a limitation of the present invention. DETAILED DESCRIPTION

[0024] The technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments in the present invention, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the present invention.

[0025] Unless otherwise defined, all professional and scientific terms used herein have the same meanings as those familiar to those skilled in the art. In addition, any methods and materials similar or equivalent to those described herein may be applied to the present invention. The preferred implementation methods and materials described herein are for demonstration purposes only and are not intended to limit the content of this application.

[0026] The experimental methods in the following examples are conventional methods unless otherwise specified, and the experimental materials used in the following examples are purchased from commercial channels unless otherwise specified.

[0027] Example 1

[0028] A pure Chinese medicine for treating acute and chronic liver diseases

[0029] The pure Chinese medicine comprises the following components in parts by weight:

[0030] 5 parts of tortoise shell with vinegar, 3 parts of American ginseng, 4 parts of Sichuan rhubarb, 2 parts of donkey-hide gelatin, 3 parts of cordyceps, 4 parts of ganoderma lucidum, 3 parts of pricking fruit, 2 parts of olea truncatum, 3 parts of cedar parasitic, 2 parts of mistletoe, 4 parts of umbellate, 3 parts of imperata, 2 parts of saffron, 3 parts of angelica, 3 parts of knotweed, 4 parts of radix schizonepetae, 2 parts of artificial bezoars, 3 parts of white peony root, 2 parts of oregano, 3 parts of wolfberry, 2 parts of schisandra, 3 parts of gardenia, 3 parts of artemisia capillaris, 2 parts of dandelion, 2 parts of safflower, 3 parts of schisandra, 2 parts of vervain, 2 parts of fennel, 2 parts of tangerine seed and 3 parts of liquorice.

[0031] Example 2

[0032] A pure Chinese medicine for treating acute and chronic liver diseases

[0033] The pure Chinese medicine comprises the following components in parts by weight:

[0034] 3 parts of vinegar tortoise shell, 2 parts of American ginseng, 3 parts of Sichuan yellow, 1.5 parts of donkey-hide gelatin, 2.5 parts of cordyceps, 3 parts of ganoderma lucidum, 2.5 parts of pricking fruit, 1.5 parts of olea truncatum, 2.5 parts of cedar parasitic, 1.5 parts of mistletoe, 3 parts of Poria, 2.5 parts of Imperatae rhizome, 1.5 parts of saffron, 2.5 parts of angelica, 2.5 parts of knotweed, 3 parts of radix scutellariae, 1.5 parts of artificial bezoar, 2.5 parts of white peony, 1.5 parts of oregano, 2.5 parts of wolfberry, 1.5 parts of schisandra, 2.5 parts of gardenia, 2.5 parts of artemisia capillaris, 1.5 parts of dandelion, 1.5 parts of safflower, 2.5 parts of safflower, 1.5 parts of smilax china, 1.5 parts of selfheal, 1.5 parts of verbena, 1.5 parts of fennel, 1.5 parts of tangerine seed and 2.5 parts of liquorice.

[0035] Example 3

[0036] A pure Chinese medicine for treating acute and chronic liver diseases

[0037] The pure Chinese medicine comprises the following components in parts by weight:

[0038] 3 parts of tortoise shell with vinegar, 2.5 parts of American ginseng, 2.5 parts of Sichuan rhubarb, 1.2 parts of donkey-hide gelatin, 2.2 parts of cordyceps, 2.5 parts of ganoderma lucidum, 2.2 parts of pricking fruit, 1.6 parts of olea truncatum, 2.2 parts of cedar parasitic, 1.6 parts of mistletoe, 2.5 parts of umbellate, 2.2 parts of imperata rhizome, 1.2 parts of saffron, 2.2 parts of angelica, 2.2 parts of knotweed, 2.5 parts of radix strychnifoliae, 1.2 parts of artificial bezoars, 2.2 parts of white peony root, 1.6 parts of oregano, 2.2 parts of wolfberry, 1.6 parts of schisandra chinensis, 2.2 parts of gardenia, 2.2 parts of artemisia capillaris, 1.6 parts of dandelion, 1.6 parts of safflower, 2.2 parts of safflower, 1.6 parts of smilax china, 1.6 parts of selfheal, 1.6 parts of verbena, 1.6 parts of fennel, 1.6 parts of tangerine seed and 2.2 parts of liquorice.

[0039] Example 4

[0040] A pure Chinese medicine for treating acute and chronic liver diseases

[0041] The pure Chinese medicine comprises the following components in parts by weight:

[0042] 3 parts of tortoise shell with vinegar, 2.2 parts of American ginseng, 2.2 parts of Sichuan rhubarb, 1.5 parts of donkey-hide gelatin, 2.2 parts of cordyceps, 2.2 parts of ganoderma lucidum, 2.2 parts of pricking fruit, 1.6 parts of olea truncatum, 2.2 parts of cedar parasitic, 1.6 parts of mistletoe, 2.2 parts of umbellate, 2.2 parts of imperata rhizome, 1.2 parts of saffron, 2.2 parts of angelica, 2.2 parts of knotweed, 2.2 parts of radix schisandrae, 1.2 parts of artificial bezoars, 2.2 parts of white peony root, 1.6 parts of oregano, 2.2 parts of wolfberry, 1.6 parts of schisandra, 2 parts of gardenia, 2.2 parts of artemisia capillaris, 1.6 parts of dandelion, 1.6 parts of safflower, 2.2 parts of smilax china, 1.6 parts of selfheal, 1.6 parts of verbena, 1.6 parts of fennel, 1.6 parts of tangerine seed and 2.2 parts of liquorice.

[0043] Example 5

[0044] A pure Chinese medicine for treating acute and chronic liver diseases

[0045] The pure Chinese medicine comprises the following components in parts by weight:

[0046] 3 parts of tortoise shell with vinegar, 2.5 parts of American ginseng, 2.5 parts of Sichuan rhubarb, 1.2 parts of donkey-hide gelatin, 2.2 parts of cordyceps, 2.5 parts of ganoderma lucidum, 2.2 parts of pricking fruit, 1.6 parts of olea truncatum, 2.2 parts of cedar parasitic, 1.6 parts of mistletoe, 2.5 parts of umbellate, 2.2 parts of imperata rhizome, 1.2 parts of saffron, 2.2 parts of angelica, 2.2 parts of knotweed, 2.5 parts of radix strychnifoliae, 1.2 parts of artificial bezoars, 2.2 parts of white peony root, 1.6 parts of oregano, 2.2 parts of wolfberry, 1.6 parts of schisandra chinensis, 2.2 parts of gardenia, 2.2 parts of artemisia capillaris, 1.6 parts of dandelion, 1.6 parts of safflower, 2.2 parts of safflower, 1.6 parts of smilax china, 1.6 parts of selfheal, 1.6 parts of verbena, 1.6 parts of fennel, 1.6 parts of tangerine seed and 2.2 parts of liquorice.

[0047] Example 5

[0048] A preparation method of pure Chinese medicine for treating acute and chronic liver diseases

[0049] The preparation method comprises the following steps:

[0050] a. Accurately weigh the above parts by weight of tortoise shell, American ginseng, Sichuan yellow, donkey-hide gelatin, cordyceps, Ganoderma lucidum, prickle fruit, Olea europaea, parasitic cedar, mistletoe, Polyporus, Imperata root, saffron, angelica, knotweed, root vegetable, artificial bezoar, white peony, oregano, wolfberry, Schisandra chinensis, gardenia, Artemisia capillaris, dandelion, safflower, chicken bone grass, selfheal, verbena, fennel, orange seed, licorice;

[0051] b. Wash the tortoise shell with vinegar, American ginseng, donkey-hide gelatin, cordyceps, ganoderma lucidum, prickle fruit, olea, fir parasitic, mistletoe, umbellate, Imperata root, artificial bezoar, white peony, oregano, wolfberry, Schisandra chinensis, gardenia, orange seed, licorice with pure water to remove dust and impurities on the surface, and then dry them naturally under well-ventilated conditions and then grind them separately until the herbs reach a fineness of more than 200 mesh and set aside;

[0052] c. Wash saffron, angelica, knotweed, root vegetable, Artemisia capillaris, dandelion, safflower, chicken bone grass, selfheal, verbena, fennel, and other medicinal materials with purified water or distilled water, dry them naturally, crush them to a fineness of more than 200 mesh, add 9 times the mass of distilled water, soak for 5 hours, boil them with high heat, then turn to low heat and keep them in a slightly boiling state for 1.5 hours, filter, collect the filtrate, add 7 times the mass of distilled water to the residue, repeat the above decoction and filtration operation, combine the two filtrates, and set aside;

[0053] d. The powder of step b and the filtrate of step c are mixed evenly, and then concentrated under reduced pressure at 65°C until it is concentrated to a thick paste with a relative density of 1.2-1.3, and the pure Chinese medicine is prepared by spray drying. The inlet air temperature of the spray drying is 170°C, the outlet air temperature is 80°C, and the atomizer speed is 12000rpm.

[0054] The preparation method can be used for preparing the pure Chinese medicine for treating acute and chronic liver diseases of the above-mentioned Examples 1-4.

[0055] Results Analysis

[0056] Evaluation of the efficacy of pure Chinese medicine in the treatment of acute and chronic liver diseases

[0057] (1) Experimental subjects:

[0058] A total of 200 patients with acute and chronic liver disease were included in this experiment, including 120 males and 80 females. The age distribution is as follows: 10 people under 20 years old, 30 people aged 21-30 years old, 40 people aged 31-40 years old, 50 people aged 41-50 years old, 40 people aged 51-60 years old, 20 people aged 61-70 years old, and 10 people over 70 years old. In terms of liver disease course: 30 people within one month, 60 people 1-3 months, 60 people 3-6 months, 30 people 6 months-1 year, and 20 people over 1 year. Past history of liver disease: 50 people within 5 years, 100 people 5-10 years, and 50 people over 10 years.

[0059] The symptoms of patients are diverse, the most common ones include: distension or dull pain in the ribs, discomfort in the liver area, fatigue, poor appetite, nausea and vomiting, abdominal distension, yellow eyes, body and urine, dull complexion, weight loss or puffiness, and some patients may have palms of the liver and spider nevi. The tongue is mostly dark red or ecchymotic, with greasy tongue coating, and a stringy or slippery pulse. In addition, most patients have abnormal liver function indicators and positive viral markers.

[0060] (2) Efficacy criteria:

[0061] According to the latest revised "Guidelines for the Diagnosis and Treatment of Acute and Chronic Liver Diseases and Criteria for Efficacy Evaluation in Traditional Chinese Medicine" by the Liver Disease Professional Committee of the Chinese Association of Traditional Chinese Medicine. The details are as follows:

[0062] First-level efficacy: clinical symptoms basically disappeared, various liver function indicators returned to normal, viral markers turned negative, and liver imaging examinations improved significantly;

[0063] Secondary efficacy: Clinical symptoms were significantly alleviated, most liver function indicators returned to normal, viral marker titers decreased significantly, and liver imaging examinations improved to a certain extent;

[0064] Level 3 efficacy: clinical symptoms are alleviated, liver function indicators are partially improved, viral markers have no significant changes, and liver imaging examinations have no significant changes;

[0065] Ineffective: There was no improvement or deterioration in clinical symptoms, liver function indicators, viral markers, and liver imaging examinations.

[0066] (3) Treatment effect:

[0067] The results are as follows Figure 1 As shown, after 3 months of treatment with this pure Chinese medicine, the treatment effects of 200 patients with acute and chronic liver diseases are as follows:

[0068] 88 patients achieved first-level efficacy, accounting for 44%;

[0069] 60 patients achieved secondary efficacy, accounting for 30%;

[0070] 32 patients achieved grade 3 efficacy, accounting for 16%;

[0071] The overall effective rate is 90%.

[0072] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

[0073] The present invention and its implementation methods are described above, which is not restrictive. The drawings are only one of the implementation methods of the present invention, and the actual application is not limited thereto. In short, if ordinary technicians in the field are inspired by it and design methods and embodiments similar to the technical solution without creativity without departing from the purpose of the invention, they should all fall within the protection scope of the present invention.

Claims

1. A pure Chinese medicine for treating acute and chronic liver diseases, characterized in that: The composition comprises the following components in parts by weight: 1-10 parts of tortoise shell with vinegar, 1-5 parts of American ginseng, 1-6 parts of Sichuan yellow, 1-3 parts of donkey-hide gelatin, 1-4 parts of cordyceps, 1-5 parts of ganoderma lucidum, 1-4 parts of pricking fruit, 1-3 parts of olea truncatum, 1-4 parts of cedar parasitic, 1-3 parts of mistletoe, 1-5 parts of umbellate, 1-4 parts of imperata rhizome, 0.5-3 parts of saffron, 1-4 parts of angelica, 1-4 parts of knotweed, 1-5 parts of radix strychnifoliae, 0.5-3 parts of artificial bezoar, 1-4 parts of white peony root, 1-3 parts of oregano, 1-4 parts of wolfberry, 1-3 parts of schisandra chinensis, 1-4 parts of gardenia, 1-4 parts of artemisia capillaris, 1-3 parts of dandelion, 1-3 parts of safflower, 1-4 parts of schisandra chinensis, 1-3 parts of vervain, 1-3 parts of fennel, 1-3 parts of orange seed and 1-4 parts of liquorice.

2. The pure Chinese medicine for treating acute and chronic liver diseases according to claim 1, characterized in that: The composition comprises the following components in parts by weight: 1-5 parts of tortoise shell with vinegar, 1-3 parts of American ginseng, 1-4 parts of Sichuan yellow, 1-2 parts of donkey-hide gelatin, 1-3 parts of cordyceps, 1-4 parts of ganoderma lucidum, 1-3 parts of pricking fruit, 1-2 parts of olea truncatum, 1-3 parts of cedar parasitic, 1-2 parts of mistletoe, 1-4 parts of umbellate, 1-3 parts of imperata root, 0.5-2 parts of saffron, 1-3 parts of angelica, 1-3 parts of knotweed, 1-4 parts of radix strychnifoliae, 0.5-2 parts of artificial bezoar, 1-3 parts of white peony root, 1-2 parts of oregano, 1-3 parts of wolfberry, 1-2 parts of schisandra, 1-3 parts of gardenia, 1-3 parts of artemisia capillaris, 1-2 parts of dandelion, 1-2 parts of safflower, 1-3 parts of schisandra, 1-2 parts of fennel, 1-2 parts of orange seed and 1-3 parts of licorice.

3. The pure Chinese medicine for treating acute and chronic liver diseases according to claim 2, characterized in that: The composition comprises the following components in parts by weight: 2-4 parts of tortoise shell with vinegar, 2-3 parts of American ginseng, 2-3 parts of Sichuan huang, 1-1.5 parts of donkey hide gelatin, 2-2.5 parts of cordyceps, 2-3 parts of ganoderma lucidum, 2-2.5 parts of prickle fruit, 1.5-1.8 parts of olea truncatum, 2-2.5 parts of cedar parasitic, 1.5-1.8 parts of mistletoe, 2-3 parts of umbellate, 2-2.5 parts of imperata root, 1-1.5 parts of saffron, 2-2.5 parts of angelica, 2-2.5 parts of knotweed, 2-2.5 parts of radix polygoni cuspidatis, 2-3 parts of radix scutellariae, 1-1 .5 parts, white peony 2-2.5 parts, oregano 1.5-1.8 parts, wolfberry 2-2.5 parts, Schisandra 1.5-1.8 parts, gardenia 2-2.5 parts, Artemisia capillaris 2-2.5 parts, dandelion 1.5-1.8 parts, safflower 1.5-1.8 parts, chicken bone grass 2-2.5 parts, selfheal 1.5-1.8 parts, verbena 1.5-1.8 parts, fennel 1.5-1.8 parts, orange seed 1.5-1.8 parts and licorice 2-2.5 parts.

4. The pure Chinese medicine for treating acute and chronic liver diseases according to claim 3, characterized in that: The composition comprises the following components in parts by weight: 3 parts of tortoise shell with vinegar, 2.5 parts of American ginseng, 2.5 parts of Sichuan rhubarb, 1.2 parts of donkey-hide gelatin, 2.2 parts of cordyceps, 2.5 parts of ganoderma lucidum, 2.2 parts of pricking fruit, 1.6 parts of olea truncatum, 2.2 parts of cedar parasitic, 1.6 parts of mistletoe, 2.5 parts of umbellate, 2.2 parts of imperata rhizome, 1.2 parts of saffron, 2.2 parts of angelica, 2.2 parts of knotweed, 2.5 parts of radix strychnifoliae, 1.2 parts of artificial bezoars, 2.2 parts of white peony root, 1.6 parts of oregano, 2.2 parts of wolfberry, 1.6 parts of schisandra chinensis, 2.2 parts of gardenia, 2.2 parts of artemisia capillaris, 1.6 parts of dandelion, 1.6 parts of safflower, 2.2 parts of safflower, 1.6 parts of smilax china, 1.6 parts of selfheal, 1.6 parts of verbena, 1.6 parts of fennel, 1.6 parts of tangerine seed and 2.2 parts of liquorice.

5. A method for preparing a pure Chinese medicine for treating acute and chronic liver diseases according to any one of claims 1 to 4, characterized in that: The following steps are involved: a. Accurately weigh the above parts by weight of tortoise shell, American ginseng, Sichuan yellow, donkey-hide gelatin, cordyceps, Ganoderma lucidum, prickle fruit, Olea europaea, parasitic cedar, mistletoe, Polyporus, Imperata root, saffron, angelica, knotweed, root vegetable, artificial bezoar, white peony, oregano, wolfberry, Schisandra chinensis, gardenia, Artemisia capillaris, dandelion, safflower, chicken bone grass, selfheal, verbena, fennel, orange seed, licorice; b. Wash the tortoise shell with vinegar, American ginseng, donkey-hide gelatin, cordyceps, ganoderma lucidum, prickle fruit, olea, fir parasitic, mistletoe, umbellate, Imperata root, artificial bezoar, white peony, oregano, wolfberry, Schisandra chinensis, gardenia, orange seed, licorice with pure water to remove dust and impurities on the surface, and then dry them naturally under well-ventilated conditions and then grind them separately until the herbs reach a fineness of more than 200 mesh and set aside; c. The saffron, angelica, knotweed, root vegetable, Artemisia capillaris, dandelion, safflower, chicken bone grass, selfheal, verbena, fennel, such herbs need to be washed with purified water or distilled water, dried naturally and crushed to a fineness of more than 200 mesh, add 8-10 times the mass of distilled water, soak for 5-6h, after the soaking is completed, first boil with high heat, then turn to low heat and keep it in a slightly boiling state for 1-2h, filter, collect the filtrate, add 6-8 times the mass of distilled water to the residue, repeat the above decoction and filtration operation, combine the two filtrates, and set aside; d. The powder of step b and the filtrate of step c are mixed evenly, and then concentrated under reduced pressure at 60-70°C until it is concentrated to a thick paste with a relative density of 1.2-1.3, and the pure Chinese medicine is prepared by spray drying.

6. The method for preparing the pure Chinese medicine for treating acute and chronic liver diseases according to claim 5, characterized in that: The parameters of the spray drying are: Inlet air temperature: 160-180℃, outlet air temperature: 70-90℃, atomizer speed: 10000-15000rpm.

7. The method for preparing the pure Chinese medicine for treating acute and chronic liver diseases according to claim 5, characterized in that: The pure Chinese medicine is in the form of pills.

8. The method for preparing the pure Chinese medicine for treating acute and chronic liver diseases according to claim 5, characterized in that: The pure Chinese medicine is a capsule.

9. The method for preparing the pure Chinese medicine for treating acute and chronic liver diseases according to claim 5, characterized in that: The pure Chinese medicine is an granule.

10. The method for preparing the pure Chinese medicine for treating acute and chronic liver diseases according to claim 5, characterized in that: The pure Chinese medicine is a powder.