Hirudin peptide probiotic beverage with vascular scavenger function

Abstract

The invention relates to the technical field of probiotic beverages, in particular to a hirudin peptide probiotic beverage with a vascular scavenger function, which is prepared from the following components in percentage by mass: 1 to 10 percent of hirudin peptide, 0.1 to 5 percent of probiotics, 2 to 5 percent of prebiotics, 1 to 5 percent of fruit juice, 0.1 to 2 percent of vitamin, 0.1 to 1 percent of mineral substance, 0.5 to 2 percent of dietary fiber, 0.1 to 1 percent of natural extract, 0.1 to 1 percent of sweetening agent, 0.01 to 0.1 percent of preservative and 70 to 90 percent of water, the hirudin peptide in the beverage serves as a core component of the beverage, has remarkable anticoagulation and thrombolysis effects and can activate a fibrin dissolution system in blood and inhibit the activity of thrombin, so that thrombosis is effectively prevented and treated, the occurrence risk of cardiovascular and cerebrovascular events is reduced, and the hirudin peptide can also expand blood vessels, increase blood flow and promote blood circulation. Microcirculation is improved, the symptoms of palpitation, chest distress, paralysis of hands and feet, dizziness and headache can be relieved, and blood circulation and thrombosis resistance are improved.

Description

Technical Field

[0001] The invention relates to the technical field of probiotic beverages, in particular to a hirudin peptide probiotic beverage with a blood vessel scavenger function. Background Art

[0002] Probiotic drinks usually contain a variety of probiotics, such as lactobacillus and bifidobacterium. These probiotics exist in the beverage in the form of live bacteria. Drinking can introduce probiotics into the intestines. The intestines are part of the human immune system. Probiotics can stimulate the activity of intestinal immune cells, enhance intestinal immunity, and thereby improve human immunity.

[0003] In some probiotic beverages, probiotics are not the core ingredients, so the amount added is relatively small, which may result in limited effect on improving intestinal health. At the same time, the functions of probiotic beverages are often relatively simple, focusing mainly on improving intestinal health, while paying less attention to other health needs, such as cardiovascular health, which leads to limited functionality of probiotic beverages.

[0004] Therefore, in view of the fact that the functions of the above-mentioned traditional probiotic beverages are often relatively simple, mainly focusing on improving intestinal health and paying less attention to cardiovascular health, a hirudin peptide probiotic beverage with vascular scavenger function can be designed. Summary of the invention

[0005] In order to overcome the problem that traditional probiotic drinks are often single in function, mainly focusing on improving intestinal health and paying less attention to cardiovascular health.

[0006] The technical scheme of the present invention is: a hirudin peptide probiotic beverage with a vascular scavenger function comprises the following components, measured by mass percentage: 1-10% of hirudin peptide, 0.1-5% of probiotics, 2-5% of prebiotics, 1-5% of fruit juice, 0.1-2% of vitamins, 0.1-1% of minerals, 0.5-2% of dietary fiber, 0.1-1% of natural extracts, 0.1-1% of sweeteners, 0.01-0.1% of preservatives, and 70-90% of water.

[0007] Preferably, the juice is a liquid squeezed or extracted from a variety of fruits, including one or more of apples, oranges, grapes and pears.

[0008] Preferably, the vitamins include one or more of vitamin C, vitamin E, and vitamin B group.

[0009] Preferably, the minerals include one or more of calcium, magnesium, zinc and iron.

[0010] Preferably, the natural extract includes one or more of seabuckthorn flavonoids, green tea extract and grape seed extract.

[0011] Preferably, the sweetener is a natural sweetener or an artificial sweetener, wherein the natural sweetener is one or more of sucrose, fructose and honey, and the artificial sweetener is one or more of aspartame and acesulfame potassium.

[0012] Preferably, the preservative comprises one or more of sodium benzoate and potassium sorbate.

[0013] The hirudin peptide probiotic beverage with blood vessel scavenging function has the following preparation steps:

[0014] Step 1: Extraction and preparation of hirudin peptide

[0015] Select fresh or refrigerated medical leeches for a period of time not exceeding a prescribed time limit to ensure the quality and activity of the raw materials, add the leeches and water into a homogenizer for homogenization, and then use a centrifuge for high-speed centrifugation at a speed of between 6,000 and 10,000 revolutions per minute, and then use a filter for filtering to obtain a precipitate, mix the precipitate with water in a reactor in a certain proportion, adjust the pH value to between 7 and 9, add alkaline protease for enzymatic hydrolysis, and the reaction time is between 8 and 12 hours. After the reaction is completed, use a freeze dryer for freeze drying to obtain hirudin peptide, and the freezing temperature is below -50°C;

[0016] Step 2: Preparation of probiotic cultures

[0017] Select excellent strains, inoculate them in appropriate culture media for cultivation, and multiply them into a large number of bacterial colonies. The culture temperature is between 30-37°C and the culture time is between 7 days and 2 weeks. The required probiotics are obtained through separation equipment and purification equipment, and then the purified probiotics are frozen or freeze-dried for storage using a freeze dryer. When subsequent mixing treatment is required, the probiotics are activated in advance and suspended in an appropriate amount of water.

[0018] Step 3: Overall raw material preparation

[0019] preparing all raw materials according to mass percentage, including hirudin peptide, probiotics, prebiotics, fruit juice, vitamins, minerals, dietary fiber, natural extracts, sweeteners, preservatives and water;

[0020] Step 4: Mixing

[0021] Put hirudin peptide, probiotics, prebiotics, fruit juice, vitamins, minerals, dietary fiber, and natural extracts into a mixer, start the stirrer to mix and stir at a speed of 500-1100 r / min, then add sweeteners and preservatives to adjust the taste and extend the shelf life, and gradually add an appropriate amount of water to make the total mass percentage meet the requirements;

[0022] Step 5: Homogenization

[0023] Use a homogenizer to homogenize the mixed raw materials to make the components more evenly dispersed;

[0024] Step 6: Sterilization

[0025] Start the sterilizer to perform high temperature sterilization or pasteurization to ensure the hygiene and safety of the beverage. The sterilization temperature is 80-110°C and the sterilization time is between 15 minutes and 1 hour;

[0026] Step 7: Filling process

[0027] The sterilized beverage is filled into suitable cans using a filling machine, and sealed and packaged using a sealing machine to ensure the hygiene and portability of the product.

[0028] Beneficial effects of the present invention:

[0029] 1. The hirudin peptide in the beverage of the present invention, as the core component of the beverage, has significant anticoagulant and thrombolytic effects. It can activate the fibrinolytic system in the blood and inhibit the activity of thrombin, thereby effectively preventing and treating thrombosis and reducing the risk of cardiovascular and cerebrovascular events. The hirudin peptide can also dilate blood vessels, increase blood flow, improve microcirculation, help relieve the symptoms of palpitations, chest tightness, numbness of hands and feet, dizziness and headache, and improve blood circulation and anti-thrombotic ability. Probiotics are an important guarantee for intestinal health. The probiotics in the beverage can inhibit the growth of harmful bacteria and increase the number of beneficial bacteria, thereby improving the balance of intestinal flora and promoting intestinal health. Prebiotics can assist in promoting the growth and reproduction of probiotics, and also help absorb and utilize nutrients and improve body immunity. The antioxidant ingredients such as natural extracts and vitamins in the beverage can remove free radicals, delay cell aging, prevent and improve skin aging. Minerals and dietary fiber are essential nutrients for the human body. The formula of the beverage contains appropriate amounts of minerals and dietary fiber, which helps maintain physical health and normal physiological functions. DETAILED DESCRIPTION

[0030] The present invention will be further described below in conjunction with the accompanying drawings and embodiments.

[0031] The present invention provides an embodiment: a hirudin peptide probiotic beverage with a vascular scavenger function, comprising the following components by mass percentage: 1-10% of hirudin peptide, 0.1-5% of probiotics, 2-5% of prebiotics, 1-5% of fruit juice, 0.1-2% of vitamins, 0.1-1% of minerals, 0.5-2% of dietary fiber, 0.1-1% of natural extracts, 0.1-1% of sweeteners, 0.01-0.1% of preservatives, and 70-90% of water. The fruit juice is a liquid squeezed or extracted from a variety of fruits, including apples, oranges, grapes and The invention discloses one or more of pears, the vitamins specifically include one or more of vitamin C, vitamin E, and vitamin B group, the minerals specifically include one or more of calcium, magnesium, zinc, and iron, the natural extracts specifically include one or more of seabuckthorn flavonoids, green tea extract, and grape seed extract, the sweeteners are natural sweeteners or artificial sweeteners, wherein the natural sweeteners are one or more of sucrose, fructose, and honey, the artificial sweeteners are one or more of aspartame and acesulfame potassium, and the preservatives specifically include one or more of sodium benzoate and potassium sorbate.

[0032] The hirudin peptide probiotic beverage with blood vessel scavenging function has the following preparation steps:

[0033] Step 1: Extraction and preparation of hirudin peptide

[0034] Select fresh or refrigerated medical leeches for a period of time not exceeding a prescribed time limit to ensure the quality and activity of the raw materials, add the leeches and water into a homogenizer for homogenization, and then use a centrifuge for high-speed centrifugation at a speed of between 6,000 and 10,000 revolutions per minute, and then use a filter for filtering to obtain a precipitate, mix the precipitate with water in a reactor in a certain proportion, adjust the pH value to between 7 and 9, add alkaline protease for enzymatic hydrolysis, and the reaction time is between 8 and 12 hours. After the reaction is completed, use a freeze dryer for freeze drying to obtain hirudin peptide, and the freezing temperature is below -50°C;

[0035] Step 2: Preparation of probiotic cultures

[0036] Select excellent strains, inoculate them in appropriate culture media for cultivation, and multiply them into a large number of bacterial colonies. The culture temperature is between 30-37°C and the culture time is between 7 days and 2 weeks. The required probiotics are obtained through separation equipment and purification equipment, and then the purified probiotics are frozen or freeze-dried for storage using a freeze dryer. When subsequent mixing treatment is required, the probiotics are activated in advance and suspended in an appropriate amount of water.

[0037] Step 3: Overall raw material preparation

[0038] preparing all raw materials according to mass percentage, including hirudin peptide, probiotics, prebiotics, fruit juice, vitamins, minerals, dietary fiber, natural extracts, sweeteners, preservatives and water;

[0039] Step 4: Mixing

[0040] Put hirudin peptide, probiotics, prebiotics, fruit juice, vitamins, minerals, dietary fiber, and natural extracts into a mixer, start the stirrer to mix and stir at a speed of 500-1100 r / min, then add sweeteners and preservatives to adjust the taste and extend the shelf life, and gradually add an appropriate amount of water to make the total mass percentage meet the requirements;

[0041] Step 5: Homogenization

[0042] Use a homogenizer to homogenize the mixed raw materials to make the components more evenly dispersed;

[0043] Step 6: Sterilization

[0044] Start the sterilizer to perform high temperature sterilization or pasteurization to ensure the hygiene and safety of the beverage. The sterilization temperature is 80-110°C and the sterilization time is between 15 minutes and 1 hour;

[0045] Step 7: Filling process

[0046] The sterilized beverage is filled into suitable cans using a filling machine, and sealed and packaged using a sealing machine to ensure the hygiene and portability of the product.

[0047] Example 1

[0048] The present invention provides an embodiment: a hirudin peptide probiotic beverage with a vascular scavenger function, comprising the following components by mass percentage: 1% of hirudin peptide, 0.1% of probiotics, 2% of prebiotics, 1% of juice, 0.1% of vitamins, 0.1% of minerals, 0.5% of dietary fiber, 0.1% of natural extracts, 0.1% of sweeteners, 0.01% of preservatives, and 70% of water, wherein the juice is a liquid squeezed or extracted from a variety of fruits, including one or more of apples, oranges, grapes and pears, and the vitamins Specifically include one or more of vitamin C, vitamin E, and vitamin B group, minerals specifically include one or more of calcium, magnesium, zinc and iron, natural extracts specifically include one or more of sea buckthorn flavonoids, green tea extract and grape seed extract, sweeteners are natural sweeteners or artificial sweeteners, wherein natural sweeteners are one or more of sucrose, fructose and honey, artificial sweeteners are one or more of aspartame and acesulfame potassium, and preservatives specifically include one or more of sodium benzoate and potassium sorbate.

[0049] The hirudin peptide probiotic beverage with blood vessel scavenging function has the following preparation steps:

[0050] Step 1: Extraction and preparation of hirudin peptide

[0051] Select fresh or refrigerated medical leeches for a period of time not exceeding a prescribed time limit to ensure the quality and activity of the raw materials, add the leeches and water into a homogenizer for homogenization, and then use a centrifuge for high-speed centrifugation at a speed of between 6,000 and 10,000 revolutions per minute, and then use a filter for filtering to obtain a precipitate, mix the precipitate with water in a reactor in a certain proportion, adjust the pH value to between 7 and 9, add alkaline protease for enzymatic hydrolysis, and the reaction time is between 8 and 12 hours. After the reaction is completed, use a freeze dryer for freeze drying to obtain hirudin peptide, and the freezing temperature is below -50°C;

[0052] Step 2: Preparation of probiotic cultures

[0053] Select excellent strains, inoculate them in appropriate culture media for cultivation, and multiply them into a large number of bacterial colonies. The culture temperature is between 30-37°C and the culture time is between 7 days and 2 weeks. The required probiotics are obtained through separation equipment and purification equipment, and then the purified probiotics are frozen or freeze-dried for storage using a freeze dryer. When subsequent mixing treatment is required, the probiotics are activated in advance and suspended in an appropriate amount of water.

[0054] Step 3: Overall raw material preparation

[0055] preparing all raw materials according to mass percentage, including hirudin peptide, probiotics, prebiotics, fruit juice, vitamins, minerals, dietary fiber, natural extracts, sweeteners, preservatives and water;

[0056] Step 4: Mixing

[0057] Put hirudin peptide, probiotics, prebiotics, fruit juice, vitamins, minerals, dietary fiber, and natural extracts into a mixer, start the stirrer to mix and stir at a speed of 500-1100 r / min, then add sweeteners and preservatives to adjust the taste and extend the shelf life, and gradually add an appropriate amount of water to make the total mass percentage meet the requirements;

[0058] Step 5: Homogenization

[0059] Use a homogenizer to homogenize the mixed raw materials to make the components more evenly dispersed;

[0060] Step 6: Sterilization

[0061] Start the sterilizer to perform high temperature sterilization or pasteurization to ensure the hygiene and safety of the beverage. The sterilization temperature is 80-110°C and the sterilization time is between 15 minutes and 1 hour;

[0062] Step 7: Filling process

[0063] The sterilized beverage is filled into suitable cans using a filling machine, and sealed and packaged using a sealing machine to ensure the hygiene and portability of the product.

[0064] Example 2

[0065] The present invention provides an embodiment: a hirudin peptide probiotic beverage with a vascular scavenger function, comprising the following components by mass percentage: 5.5% of hirudin peptide, 2% of probiotics, 3.5% of prebiotics, 2.5% of juice, 1.2% of vitamins, 0.5% of minerals, 1.3% of dietary fiber, 0.5% of natural extracts, 0.4% of sweeteners, 0.06% of preservatives, and 80% of water, wherein the juice is a liquid squeezed or extracted from a variety of fruits, including one or more of apples, oranges, grapes and pears, and the vitamins The vitamins specifically include one or more of vitamin C, vitamin E, and vitamin B group, the minerals specifically include one or more of calcium, magnesium, zinc, and iron, the natural extracts specifically include one or more of seabuckthorn flavonoids, green tea extract, and grape seed extract, the sweeteners are natural sweeteners or artificial sweeteners, wherein the natural sweeteners are one or more of sucrose, fructose, and honey, the artificial sweeteners are one or more of aspartame and acesulfame potassium, and the preservatives specifically include one or more of sodium benzoate and potassium sorbate.

[0066] The hirudin peptide probiotic beverage with blood vessel scavenging function has the following preparation steps:

[0067] Step 1: Extraction and preparation of hirudin peptide

[0068] Select fresh or refrigerated medical leeches for a period of time not exceeding a prescribed time limit to ensure the quality and activity of the raw materials, add the leeches and water into a homogenizer for homogenization, and then use a centrifuge for high-speed centrifugation at a speed of between 6,000 and 10,000 revolutions per minute, and then use a filter for filtering to obtain a precipitate, mix the precipitate with water in a reactor in a certain proportion, adjust the pH value to between 7 and 9, add alkaline protease for enzymatic hydrolysis, and the reaction time is between 8 and 12 hours. After the reaction is completed, use a freeze dryer for freeze drying to obtain hirudin peptide, and the freezing temperature is below -50°C;

[0069] Step 2: Preparation of probiotic cultures

[0070] Select excellent strains, inoculate them in appropriate culture media for cultivation, and multiply them into a large number of bacterial colonies. The culture temperature is between 30-37°C and the culture time is between 7 days and 2 weeks. The required probiotics are obtained through separation equipment and purification equipment, and then the purified probiotics are frozen or freeze-dried for storage using a freeze dryer. When subsequent mixing treatment is required, the probiotics are activated in advance and suspended in an appropriate amount of water.

[0071] Step 3: Overall raw material preparation

[0072] preparing all raw materials according to mass percentage, including hirudin peptide, probiotics, prebiotics, fruit juice, vitamins, minerals, dietary fiber, natural extracts, sweeteners, preservatives and water;

[0073] Step 4: Mixing

[0074] Put hirudin peptide, probiotics, prebiotics, fruit juice, vitamins, minerals, dietary fiber, and natural extracts into a mixer, start the stirrer to mix and stir at a speed of 500-1100 r / min, then add sweeteners and preservatives to adjust the taste and extend the shelf life, and gradually add an appropriate amount of water to make the total mass percentage meet the requirements;

[0075] Step 5: Homogenization

[0076] Use a homogenizer to homogenize the mixed raw materials to make the components more evenly dispersed;

[0077] Step 6: Sterilization

[0078] Start the sterilizer to perform high temperature sterilization or pasteurization to ensure the hygiene and safety of the beverage. The sterilization temperature is 80-110°C and the sterilization time is between 15 minutes and 1 hour;

[0079] Step 7: Filling process

[0080] The sterilized beverage is filled into suitable cans using a filling machine, and sealed and packaged using a sealing machine to ensure the hygiene and portability of the product.

[0081] Example 3

[0082] The present invention provides an embodiment: a hirudin peptide probiotic beverage with a vascular scavenger function, comprising the following components, in percentage by mass: 10% hirudin peptide, 5% probiotics, 5% prebiotics, 5% fruit juice, 2% vitamins, 1% minerals, 2% dietary fiber, 1% natural extracts, 1% sweeteners, 0.1% preservatives, and 90% water, wherein the fruit juice is a liquid squeezed or extracted from a variety of fruits, including one or more of apples, oranges, grapes, and pears, the vitamins specifically include one or more of vitamin C, vitamin E, and vitamin B group, the minerals specifically include one or more of calcium, magnesium, zinc, and iron, the natural extracts specifically include one or more of seabuckthorn flavonoids, green tea extracts, and grape seed extracts, the sweeteners are natural sweeteners or artificial sweeteners, wherein the natural sweeteners are one or more of sucrose, fructose, and honey, the artificial sweeteners are one or more of aspartame and acesulfame potassium, and the preservatives specifically include one or more of sodium benzoate and potassium sorbate.

[0083] The hirudin peptide probiotic beverage with blood vessel scavenging function has the following preparation steps:

[0084] Step 1: Extraction and preparation of hirudin peptide

[0085] Select fresh or refrigerated medical leeches for a period of time not exceeding a prescribed time limit to ensure the quality and activity of the raw materials, add the leeches and water into a homogenizer for homogenization, and then use a centrifuge for high-speed centrifugation at a speed of between 6,000 and 10,000 revolutions per minute, and then use a filter for filtering to obtain a precipitate, mix the precipitate with water in a reactor in a certain proportion, adjust the pH value to between 7 and 9, add alkaline protease for enzymatic hydrolysis, and the reaction time is between 8 and 12 hours. After the reaction is completed, use a freeze dryer for freeze drying to obtain hirudin peptide, and the freezing temperature is below -50°C;

[0086] Step 2: Preparation of probiotic cultures

[0087] Select excellent strains, inoculate them in appropriate culture media for cultivation, and multiply them into a large number of bacterial colonies. The culture temperature is between 30-37°C and the culture time is between 7 days and 2 weeks. The required probiotics are obtained through separation equipment and purification equipment, and then the purified probiotics are frozen or freeze-dried for storage using a freeze dryer. When subsequent mixing treatment is required, the probiotics are activated in advance and suspended in an appropriate amount of water.

[0088] Step 3: Overall raw material preparation

[0089] preparing all raw materials according to mass percentage, including hirudin peptide, probiotics, prebiotics, fruit juice, vitamins, minerals, dietary fiber, natural extracts, sweeteners, preservatives and water;

[0090] Step 4: Mixing

[0091] Put hirudin peptide, probiotics, prebiotics, fruit juice, vitamins, minerals, dietary fiber, and natural extracts into a mixer, start the stirrer to mix and stir at a speed of 500-1100 r / min, then add sweeteners and preservatives to adjust the taste and extend the shelf life, and gradually add an appropriate amount of water to make the total mass percentage meet the requirements;

[0092] Step 5: Homogenization

[0093] Use a homogenizer to homogenize the mixed raw materials to make the components more evenly dispersed;

[0094] Step 6: Sterilization

[0095] Start the sterilizer to perform high temperature sterilization or pasteurization to ensure the hygiene and safety of the beverage. The sterilization temperature is 80-110°C and the sterilization time is between 15 minutes and 1 hour;

[0096] Step 7: Filling process

[0097] The sterilized beverage is filled into suitable cans using a filling machine, and sealed and packaged using a sealing machine to ensure the hygiene and portability of the product.

[0098] Patients with cardiovascular diseases of different age groups were selected as subjects, and the subjects were randomly divided into two groups. One group drank a traditional common probiotic beverage as a control group, and the other group drank the hirudin peptide probiotic beverages of Examples 1, 2 and 3 as an experimental group. After 8 weeks of consumption, the blood pressure and blood lipid indexes of the subjects in the experimental group and the control group were tested to evaluate the improvement effect of hirudin peptide on cardiovascular health. The test data are as follows:

[0099]

[0100] Table 1.

Claims

1. A hirudin peptide probiotic beverage with vascular scavenger function, comprising the following components, measured by mass percentage: 1-10% hirudin peptide, 0.1-5% probiotics, 2-5% prebiotics, 1-5% fruit juice, 0.1-2% vitamins, 0.1-1% minerals, 0.5-2% dietary fiber, 0.1-1% natural extracts, 0.1-1% sweeteners, 0.01-0.1% preservatives, and 70-90% water.

2. The hirudin peptide probiotic beverage with vascular scavenging function according to claim 1, characterized in that: Juice is the liquid squeezed or extracted from a variety of fruits, including one or more of apples, oranges, grapes and pears.

3. The hirudin peptide probiotic beverage with vascular scavenger function according to claim 1, characterized in that: Vitamins specifically include one or more of vitamin C, vitamin E, and vitamin B group.

4. The hirudin peptide probiotic beverage with vascular scavenging function according to claim 1, characterized in that: The minerals specifically include one or more of calcium, magnesium, zinc and iron.

5. The hirudin peptide probiotic beverage with vascular scavenging function according to claim 1, characterized in that: The natural extract specifically includes one or more of seabuckthorn flavonoids, green tea extract and grape seed extract.

6. The hirudin peptide probiotic beverage with vascular scavenger function according to claim 1, characterized in that: The sweetener is a natural sweetener or an artificial sweetener, wherein the natural sweetener is one or more of sucrose, fructose and honey, and the artificial sweetener is one or more of aspartame and acesulfame potassium.

7. The hirudin peptide probiotic beverage with vascular scavenger function according to claim 1, characterized in that: The preservative specifically includes one or more of sodium benzoate and potassium sorbate.

8. The hirudin peptide probiotic beverage with vascular scavenger function according to claim 1, characterized in that: The preparation steps are as follows: Step 1: Extraction and preparation of hirudin peptide Select fresh or refrigerated medical leeches for a period of time not exceeding a prescribed time limit to ensure the quality and activity of the raw materials, add the leeches and water into a homogenizer for homogenization, and then use a centrifuge for high-speed centrifugation at a speed of between 6,000 and 10,000 revolutions per minute, and then use a filter for filtering to obtain a precipitate, mix the precipitate with water in a reactor in a certain proportion, adjust the pH value to between 7 and 9, add alkaline protease for enzymatic hydrolysis, and the reaction time is between 8 and 12 hours. After the reaction is completed, use a freeze dryer for freeze drying to obtain hirudin peptide, and the freezing temperature is below -50°C; Step 2: Preparation of probiotic cultures Select excellent strains, inoculate them in appropriate culture media for cultivation, and multiply them into a large number of bacterial colonies. The culture temperature is between 30-37°C and the culture time is between 7 days and 2 weeks. The required probiotics are obtained through separation equipment and purification equipment, and then the purified probiotics are frozen or freeze-dried for storage using a freeze dryer. When subsequent mixing treatment is required, the probiotics are activated in advance and suspended in an appropriate amount of water. Step 3: Overall raw material preparation preparing all raw materials according to mass percentage, including hirudin peptide, probiotics, prebiotics, fruit juice, vitamins, minerals, dietary fiber, natural extracts, sweeteners, preservatives and water; Step 4: Mixing Put hirudin peptide, probiotics, prebiotics, fruit juice, vitamins, minerals, dietary fiber, and natural extracts into a mixer, start the stirrer to mix and stir at a speed of 500-1100 r / min, then add sweeteners and preservatives to adjust the taste and extend the shelf life, and gradually add an appropriate amount of water to make the total mass percentage meet the requirements; Step 5: Homogenization Use a homogenizer to homogenize the mixed raw materials to make the components more evenly dispersed; Step 6: Sterilization Start the sterilizer to perform high temperature sterilization or pasteurization to ensure the hygiene and safety of the beverage; Step 7: Filling process The sterilized beverage is filled into suitable cans using a filling machine, and sealed and packaged using a sealing machine to ensure the hygiene and portability of the product.

9. The hirudin peptide probiotic beverage with vascular scavenging function according to claim 1, characterized in that: The sterilization temperature in step six is ​​between 80-110°C, and the sterilization time is between 15 minutes and 1 hour.

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