Atrial fibrillation detection method and device based on single measurement and multiple pressurization, and medium

Abstract

The invention discloses an atrial fibrillation detection method and device based on single measurement and multiple pressurization, and a medium. The method comprises the steps that in the blood pressure reduction process of blood pressure measurement, pulse sequences corresponding to target pressure are obtained, when the maximum amplitude appears, if the number of the current pulse sequences is smaller than a preset threshold value, pressurization is adjusted to the next target pressure, then the pulse sequences continue to be obtained, and whether the number of the current pulse sequences is smaller than the preset threshold value or not is judged; and repeating the above adjustment steps until a sufficient number of amplitude sequences are obtained, and judging the atrial fibrillation after a sufficient number of pulse sequences are obtained. According to the scheme, the time for multiple times of pressurization can be further shortened, and the additionally increased time is not too long while enough pulse sequences are obtained, so that the user experience is better, the accuracy and reference of the obtained multiple pulse interval sequence data can be guaranteed, data guarantee is provided for the judgment result of atrial fibrillation, and misjudgment is avoided.

Description

Technical Field

[0001] The present invention relates to the technical field of blood pressure measurement, and in particular to a method, device and medium for detecting atrial fibrillation based on single measurement and multiple pressurization. Background Art

[0002] The statements in this section merely provide background technical information related to the present application and do not necessarily constitute prior art.

[0003] The blood pressure measurement equipment currently used can obtain the blood pressure measurement value through the pulse wave signal when measuring blood pressure. The pulse wave signal is a fluctuation caused by the contraction of the heart, which reflects the changes in blood pressure. In blood pressure measurement, the oscillometric method is usually used to detect the pulse wave signal. This method uses an inflated pressurized cuff to block arterial blood flow, and then gradually deflates the air to release the pressure, while detecting the gas pressure in the cuff and extracting the weak pulse wave signal; when the cuff pressure is much higher than the systolic pressure, the pulse wave disappears; as the cuff pressure drops to the systolic pressure, the pulse begins to appear; when the cuff pressure continues to drop, the pulse wave amplitude will gradually increase and reach the maximum value at the average pressure. Based on the relationship between the pulse wave amplitude and the cuff pressure, the blood pressure measurement value can be estimated.

[0004] By analyzing the pulse wave signal, the health status of the cardiovascular system can also be evaluated. For example, the electronic blood pressure meter disclosed in the patent publication number CN116634947A and the method for determining atrial fibrillation in the electronic blood pressure meter use a method of summing up the data groups of more than three measurement opportunities of the tester to find the average value of the pulse wave interval, and based on whether there is irregular pulse wave data exceeding a preset allowable range relative to the average value in the summed data group, it is determined whether there is a possibility of atrial fibrillation, and the presence of atrial fibrillation is determined based on three independent sequences of pulse beats.

[0005] It is not difficult to find that in the prior art of using a blood pressure measurement device to determine the presence of atrial fibrillation, it is necessary to obtain multiple independent sequences through multiple pressurization measurements to determine the presence of atrial fibrillation, which causes a bad experience for users and prolongs the measurement time a lot.

[0006] Therefore, how to solve the problem in the prior art that multiple independent data need to be obtained through multiple pressurization measurements to determine the presence of atrial fibrillation, resulting in poor user measurement experience and long measurement time, has become a topic to be studied and solved by the present invention. Summary of the invention

[0007] The purpose of the present invention is to provide a method, device and medium for detecting atrial fibrillation based on single measurement and multiple pressurization.

[0008] To achieve the above-mentioned object, the first aspect of the present invention proposes an atrial fibrillation detection method based on single measurement and multiple pressurization, which is used to determine whether atrial fibrillation exists during blood pressure measurement. The innovation point of the method is that the method comprises:

[0009] During the blood pressure reduction process of blood pressure measurement, the pulse sequence corresponding to the target pressure is obtained. When the maximum amplitude appears, if the number of current pulse sequences is less than the preset threshold, the pressure is adjusted to the next target pressure and then the pulse sequence is continued to be obtained. Then, it is determined whether the number of current pulse sequences is less than the preset threshold. The above adjustment steps are repeated until a sufficient number of amplitude sequences are obtained.

[0010] After obtaining a sufficient number of pulse sequences, atrial fibrillation is judged, and a difference sequence of pulse intervals is calculated based on the obtained multiple pulse amplitude sequences to determine whether atrial fibrillation exists, and the difference sequence is divided into multiple small sequences to determine whether atrial fibrillation exists.

[0011] The second aspect of the present invention provides a blood pressure measurement device, which includes a main control unit, a display unit, a pressurizing unit, a decompressing unit, a pressure pulse detection unit and an atrial fibrillation determination unit; wherein,

[0012] The pressure pulse detection unit is used to obtain the pulse sequence corresponding to the target pressure and transmit it to the main control unit for calculation and processing;

[0013] The main control unit is electrically connected to the display unit, the pressure pulse detection unit, the atrial fibrillation judgment unit, the pressurization unit and the decompression unit. The main control unit controls the pressurization unit to pressurize to a preset target pressure, and then controls the decompression unit to slowly reduce the pressure. In a single decompression process of slowly reducing the pressure, a sufficient number of pulse interval sequences are obtained, and when the maximum amplitude appears, if the current number of amplitude sequences is less than a preset threshold, the pressurization is adjusted to the next target pressure and the pulse sequence is continued to be obtained, and then it is determined whether the current number of pulse sequences is less than the preset threshold, and the above adjustment steps are repeated until a sufficient number of amplitude sequences are obtained;

[0014] The atrial fibrillation determination unit determines atrial fibrillation after acquiring a sufficient number of amplitude sequences, so as to finally determine whether atrial fibrillation exists;

[0015] The pressurizing unit is used to control the pressurization of the cuff airbag, pressurize the cuff airbag to a target pressure, and accept the control of the main control unit to adjust the pressurization to the next target pressure;

[0016] The decompression part is used to slowly deflate the cuff airbag during the decompression process;

[0017] The display unit is used to display the blood pressure result calculated by the main control unit, the atrial fibrillation result determined by the atrial fibrillation determination unit, and the status information of the measurement process.

[0018] The third aspect of the present invention proposes a readable storage medium, on which a control program is stored. When the control program is executed by a main control unit, the main control unit executes the steps of the atrial fibrillation detection method based on single measurement and multiple pressurization as described in the first aspect.

[0019] The relevant contents of the present invention are explained as follows:

[0020] 1. The implementation of the above technical solution of the present invention is to address the problems of poor user experience and long measurement time caused by the need to obtain multiple independent sequences through multiple pressurization measurements in the prior art to determine the presence of atrial fibrillation. An atrial fibrillation detection method based on multiple pressurizations in a single blood pressure measurement is innovatively designed to obtain enough pulse sequences to further determine the presence of atrial fibrillation according to multiple pressurizations in a single blood pressure measurement process during blood pressure measurement, a blood pressure measurement device using this method, and a readable storage medium. In this scheme, in order to obtain a sufficient number of correct pulse sequences, during the blood pressure reduction process of blood pressure measurement, the pulse sequence corresponding to the target pressure is obtained. When the maximum amplitude appears, if the current number of pulse sequences is less than the preset threshold, the pressurization is adjusted to the next target pressure and then the pulse sequence is continued to be obtained. Then it is determined whether the current number of pulse sequences is less than the preset threshold. The above adjustment steps are repeated until a sufficient number of amplitude sequences are obtained, until a sufficient number of pulse waves are detected, so that sufficient data can be obtained during the decompression process of a single blood pressure measurement to make atrial fibrillation judgment, without requiring the user to go through the pressurization and decompression process of multiple blood pressure measurements, thereby avoiding user discomfort and reducing the time for atrial fibrillation judgment. In addition, the method of adjusting the pressurization to the next target pressure and then continuing to obtain the pulse sequence does not necessarily require the pressurization to the first target pressure value when multiple pressurizations are performed during the decompression process. The pressurization time can be further shortened, which can improve User experience; in the step of judging the presence of atrial fibrillation by difference sequence, the pulse interval difference sequence is calculated according to the multiple pulse interval sequences obtained, and the pulse interval difference sequence is used to judge whether the change of the pulse sequence is greater than the pulse change threshold, so as to further ensure the accuracy and reference of the multiple pulse interval sequence data obtained, so as to provide data guarantee for subsequent judgments and avoid the occurrence of misjudgments; in the step of judging the presence of atrial fibrillation by small sequence, the pulse interval difference sequence is evenly distributed into multiple small sequences, and then each small sequence is judged and counted, so as to further achieve the purpose of using the data obtained in the decompression process of a single blood pressure measurement to judge the presence of atrial fibrillation, and the process more accurately and finely judges the "digital information" presented in the pulse amplitude signal sequence corresponding to atrial fibrillation, so as to further avoid misjudgment of atrial fibrillation. Through the application of the above-mentioned atrial fibrillation detection method and device based on single measurement and multiple pressurization, it is possible to obtain sufficient pulse interval sequence data during the decompression process of a single blood pressure measurement to perform difference sequence judgment on the presence of atrial fibrillation and small sequence judgment on the presence of atrial fibrillation. The multiple pressurization time can be further shortened, and the additional time added while obtaining sufficient pulse sequences will not be too long, thereby providing a better user experience, and ensuring the accuracy and reference of the multiple pulse interval sequence data obtained, providing data guarantee for the judgment result of atrial fibrillation and avoiding misjudgment.

[0021] 2. In the first aspect of the above technical solution, the next target pressure is adjusted by one or both of the following methods:

[0022] The preset target pressure value is used; the next target pressure is calculated according to the pulse sequence of the pulse. In this way, the next target pressure can be adjusted flexibly, and there are more options for interference or other problems in blood pressure measurement, so as to ensure that a sufficient number of pulse sequences can be obtained, the data can be correct, and the time for multiple pressurization can be shortened.

[0023] 3. In the first aspect of the above technical solution, in the method of calculating the next target pressure based on the pulse sequence of the pulse, the number of pulse sequences that need to be detected is calculated by the preset threshold of the pulse sequence and the number of pulse sequences currently detected, and the appropriate next target pressure is selected by judging that the number of pulse sequences from the end of the deflation point to the target pressure value is equal to the number of pulse sequences that need to be detected. In this way, the next target pressure is determined in a scientific and reasonable manner, so that the time required for multiple pressurization operations can be shortened, and the user can feel better about the multiple pressurizations.

[0024] 4. In the first aspect of the above technical solution, for the selection of the appropriate next target, the deflation speed of the deflation valve is defined as V, the pressure at the end of deflation is defined as P0, the number of pulse sequences to be detected is N, the pulse rate of the subject is PR, and the appropriate next target pressure value P satisfies: (P-P0) / V=N / PR, that is, P=(N / PR)*V+P0. In this more scientific and reasonable way, the appropriate next target pressure value is obtained, so that the pressure control of multiple pressurizations is more in line with the pulse rate of the current user, and the next target pressure can be adjusted according to the pulse rate of different users. Different users and different situations can have different adjustment methods for the judgment of atrial fibrillation under blood pressure measurement, thereby increasing the number of applicable users.

[0025] 5. In the first aspect of the above technical solution, find the maximum amplitude of the obtained pulse sequence Ai, where i is a positive integer from 1 to n, representing the position of the pulse sequence on the time axis. The maximum amplitude is denoted as Amax. Set the maximum amplitude judgment adjustment coefficient R and the maximum amplitude judgment times threshold Nr. If the number of amplitudes Ai < Amax * R after the maximum amplitude is greater than or equal to Nr, it indicates that the maximum amplitude appears, and the slow deflation ends. After the maximum amplitude appears, determine whether the number k of the obtained pulse sequences is less than the preset threshold. If it is greater, end this blood pressure measurement. If it is less, repeat the loop. Through the implementation of this step, through the accurate and reliable confirmation of the maximum amplitude, the accuracy and referenceability of the number of obtained amplitude sequences are further guaranteed, providing data guarantee for subsequent judgments and avoiding misjudgments. More specifically, R ranges from 0.2 to 1.0, and Nr ≥ 1. For example, R can be taken as 0.7 and Nr can be taken as 3, so as to make the values of the maximum amplitude judgment adjustment coefficient R and the maximum amplitude judgment times threshold Nr more reasonable, and balance the time spent in the decompression process of a single blood pressure measurement and the number of pulse sequences required to be obtained.

[0026] 6. In the first aspect of the above technical solution, limit the loop for the adjustment step of adjusting the pressure to the next target pressure, continuing to obtain the pulse sequence, and then determining whether the current number of amplitude sequences is less than the preset threshold. The loop limit is a finite number of times. When the finite number of times is reached, the loop is forced to end, and atrial fibrillation is judged based on all the obtained pulse sequences, so as to avoid the situation of too many loop times and too long atrial fibrillation time, and further improve the user experience.

[0027] 7. In the first aspect of the above technical solution, in the step of calculating the difference sequence of pulse intervals based on the obtained multiple pulse amplitude sequences to determine whether there is atrial fibrillation, the following steps are included:

[0028] Calculate the difference sequence of pulse intervals;

[0029] Calculate the average interval change amount and average interval amount of the pulse interval sequence;

[0030] Calculate the average change amount of the pulse interval sequence and the overall change amount of the pulse interval sequence;

[0031] The set pulse change thresholds include an average threshold and an overall threshold. Determine whether the average change amount of the pulse interval sequence is greater than the average threshold and the overall change amount of the pulse interval sequence is greater than the overall threshold;

[0032] If not, judge that atrial fibrillation does not exist. If so, judge that atrial fibrillation exists and perform the step of dividing the difference sequence into multiple small sequences and then determining whether there is atrial fibrillation.

[0033] Through the implementation of this step, the pulse interval difference sequence is calculated based on the multiple pulse interval sequences obtained, and the pulse interval difference sequence is used to determine whether the change in the pulse sequence is greater than the pulse change threshold, thereby further ensuring the accuracy and referenceability of the multiple pulse interval sequence data obtained, thereby providing data guarantee for subsequent judgments and avoiding the occurrence of misjudgments.

[0034] 8. In the first aspect of the above technical solution, the step of calculating the difference sequence of pulse intervals based on the acquired multiple pulse amplitude sequences to determine whether atrial fibrillation exists includes the following steps:

[0035] Calculate the pulse interval difference sequence Ri, where Ri = (ΔAi+1)-(ΔAi);

[0036] The average interval change St is calculated by the pulse interval difference sequence Ri, Where n is the number of pulse interval difference sequences Ri; the average interval amount Sr is calculated by the pulse interval difference sequence Ri,

[0037] Calculate the average change of the pulse interval sequence ΔS, ΔS = St / Sr; calculate the overall change of the pulse interval sequence ΔD,

[0038] The pulse change thresholds set include an average threshold ΔSk and an overall threshold ΔDk, and it is judged whether the average change ΔS is greater than the average threshold ΔSk and the overall change ΔD is greater than the overall threshold ΔDk, where ΔSk and ΔDk are both greater than 0;

[0039] If ΔS>ΔSk and ΔD>ΔDk cannot be satisfied simultaneously, it is judged that atrial fibrillation does not exist. If ΔS>ΔSk and ΔD>ΔDk are satisfied simultaneously, it is judged that atrial fibrillation exists and the difference sequence is distributed into multiple small sequences to determine whether atrial fibrillation exists.

[0040] Through the implementation of this step, the application settings of algorithms and parameters are reasonable and scientific, and the steps and applications therein can provide data guarantee for subsequent judgments.

[0041] 9. In the first aspect of the above technical solution, the step of determining whether atrial fibrillation exists after allocating the difference sequence into a plurality of small sequences comprises the following steps:

[0042] Evenly distribute the pulse interval difference sequence into multiple small sequences;

[0043] Calculate the average change of each small sequence and the overall change of each small sequence respectively;

[0044] Determine whether the average change of the small sequence is greater than the average threshold and the overall change of the small sequence is greater than the overall threshold;

[0045] If both the average change of the small sequence is greater than the average threshold and the overall change of the small sequence is greater than the overall threshold, the sequence result of the small sequence is counted; if not, it is not counted;

[0046] Calculate sequence results and values;

[0047] Determine whether the sequence result and value are greater than the result setting value;

[0048] If the sum of the sequence results is greater than the result setting value, it is determined that atrial fibrillation exists; if the sum of the sequence results is less than the result setting value, atrial fibrillation does not exist.

[0049] By implementing this step, the purpose of using the data obtained during the decompression process of a single blood pressure measurement to determine the presence of atrial fibrillation is further achieved, and this process more accurately and finely determines the "digital information" presented in the pulse amplitude signal sequence corresponding to atrial fibrillation, thereby further avoiding misjudgment of atrial fibrillation.

[0050] 10. In the first aspect of the above technical solution, the step of determining whether atrial fibrillation exists after allocating the difference sequence into a plurality of small sequences comprises the following steps:

[0051] The pulse interval difference sequence is evenly divided into m small sequences;

[0052] Calculate the average change ΔSj of each small sequence and the overall change ΔDj of each small sequence respectively, where j ranges from 1 to m;

[0053] Determine whether the average change ΔSj of the small sequence is greater than the average threshold ΔSk and the overall change ΔDj of the small sequence is greater than the overall threshold ΔDk;

[0054] If the average change ΔSj of the small sequence is greater than the average threshold ΔSk and the overall change ΔDj of the small sequence is greater than the overall threshold ΔDk, the sequence result of the small sequence is counted as 1, otherwise, it is not counted;

[0055] Calculate sequence results and values;

[0056] Determine whether the sequence result and value are greater than the result setting value C, where C ranges from 1 to m;

[0057] If the sum of the sequence results is greater than the result setting value, it is determined that atrial fibrillation exists; if the sum of the sequence results is less than the result setting value, atrial fibrillation does not exist.

[0058] Through the implementation of this step, the numerical value setting is reasonable and scientific, the pulse interval sequence obtained by a single blood pressure measurement can be used for judgment, and misjudgment can be avoided.

[0059] Due to the application of the above scheme, the present invention has the following advantages and effects compared with the prior art:

[0060] 1. Through the implementation of the technical solution of the present invention, the problems of poor user experience and long measurement time caused by the need to obtain multiple independent sequences through multiple pressurization measurements to determine the presence of atrial fibrillation in the prior art are addressed. An atrial fibrillation detection method based on multiple pressurizations in a single blood pressure measurement is innovatively designed to further determine the presence of atrial fibrillation by obtaining enough pulse sequences through multiple pressurizations during a single blood pressure measurement, a blood pressure measurement device using this method, and a readable storage medium, so as to avoid multiple measurements taking too long and improve user experience.

[0061] 2. Through the implementation of the technical solution of the present invention, in this solution, in order to obtain a sufficient number of correct pulse sequences, in the process of reducing blood pressure during blood pressure measurement, the pulse sequence corresponding to the target pressure is obtained. When the maximum amplitude appears, if the current number of pulse sequences is less than the preset threshold, the pressurization is adjusted to the next target pressure and then the pulse sequence is continued to be obtained. Then it is determined whether the current number of pulse sequences is less than the preset threshold. The above adjustment steps are repeated until a sufficient number of amplitude sequences are obtained, until a sufficient number of pulse waves are detected, so that sufficient data can be obtained during the decompression process of a single blood pressure measurement to make atrial fibrillation judgment, without letting the user go through the pressurization and decompression process of multiple blood pressure measurements, avoiding user discomfort and reducing the time for atrial fibrillation judgment. In addition, the method of continuing to obtain the pulse sequence after adjusting the pressurization to the next target pressure does not necessarily require pressurization to the first target pressure value when multiple pressurizations are performed during the decompression process. The pressurization time can be further shortened, which can improve the user experience.

[0062] 3. Through the implementation of the technical solution of the present invention, in the step of judging the presence of atrial fibrillation by using a difference sequence, a pulse interval difference sequence is calculated based on the multiple pulse interval sequences obtained, and the pulse interval difference sequence is used to judge whether the change of the pulse sequence is greater than the pulse change threshold, so as to further ensure the accuracy and reference of the multiple pulse interval sequence data obtained, so as to provide data guarantee for subsequent judgments and avoid the occurrence of misjudgments; in the step of judging the presence of atrial fibrillation by using a small sequence, the pulse interval difference sequence is evenly distributed into multiple small sequences, and then each small sequence is judged and counted, so as to further achieve the purpose of using the data obtained in the decompression process of a single blood pressure measurement to judge the presence of atrial fibrillation, and the process more accurately and finely judges the "digital information" presented in the pulse amplitude signal sequence corresponding to atrial fibrillation, so as to further avoid misjudgment of atrial fibrillation.

[0063] 4. In summary, through the application of the above-mentioned atrial fibrillation detection method and device based on single measurement and multiple pressurization, it is possible to obtain sufficient pulse interval sequence data during the decompression process of a single blood pressure measurement to perform difference sequence judgment on the presence of atrial fibrillation and small sequence judgment on the presence of atrial fibrillation. The multiple pressurization time can be further shortened, and the additional time added while obtaining sufficient pulse sequences will not be too long, thereby providing a better user experience, and ensuring the accuracy and reference of the multiple pulse interval sequence data obtained, providing data guarantee for the judgment results of atrial fibrillation and avoiding misjudgment. BRIEF DESCRIPTION OF THE DRAWINGS

[0064] Figure 1 This is a three-dimensional schematic diagram of the appearance of a blood pressure measurement device according to an embodiment of the present invention;

[0065] Figure 2 is a block diagram of the composition of a blood pressure measurement device according to an embodiment of the present invention;

[0066] Figure 3 This is a flow chart of adjusting the next target pressure according to an embodiment of the present invention.

[0067] Figure 4 The pulse waveform detection and judgment process of the embodiment of the present invention;

[0068] Figure 5 This is a flow chart of determining the presence of atrial fibrillation using a difference sequence according to an embodiment of the present invention;

[0069] Figure 6 This is a flow chart of a small sequence for determining the presence of atrial fibrillation according to an embodiment of the present invention;

[0070] Figure 7 Schematic diagram of characteristic points of the measurement process. DETAILED DESCRIPTION

[0071] In order to make the above-mentioned purposes, features and advantages of the present application more obvious and easy to understand, the specific implementation methods of the present application are described in detail below in conjunction with the accompanying drawings. In the following description, many specific details are set forth to facilitate a full understanding of the present application. However, the present application can be implemented in many other ways different from those described herein, and those skilled in the art can make similar improvements without violating the connotation of the present application, so the present application is not limited by the specific embodiments disclosed below.

[0072] The terms used herein are only for describing specific embodiments and are not intended to be limiting of the present invention. Singular forms such as "a", "this", "here", "this" and "the" as used herein also include plural forms.

[0073] The terms “first”, “second”, etc. used in this document do not specifically refer to an order or sequence, nor are they used to limit the present case. They are only used to distinguish components or operations described with the same technical terms.

[0074] As used herein, “connected” or “positioned” may refer to two or more components or devices being in direct physical contact with each other, or being in indirect physical contact with each other, or may refer to two or more components or devices operating or moving with each other.

[0075] The terms “include,” “including,” “have,” etc. used in this document are open-ended terms, meaning including but not limited to.

[0076] The terms used herein generally have the ordinary meanings of each term used in the art, in the context of the present invention, and in the specific context, unless otherwise noted. Certain terms used to describe the present invention will be discussed below or elsewhere in this specification to provide additional guidance to those skilled in the art regarding the description of the present invention.

[0077] The present invention aims to provide an atrial fibrillation detection method based on multiple pressurizations in a single measurement, a blood pressure measuring device using the method, and a readable storage medium solution, in which multiple pressurizations are performed during a single blood pressure measurement to obtain a sufficient number of pulse sequences to further determine the presence of atrial fibrillation, so as to solve the problems of poor user experience and long measurement time caused by the need to obtain multiple independent sequences through multiple pressurization measurements to determine the presence of atrial fibrillation in the prior art.

[0078] Embodiment 1: Embodiment 1 of the present invention proposes a method for detecting atrial fibrillation based on single measurement and multiple pressurization, which is used to determine whether atrial fibrillation exists during blood pressure measurement. The innovation of the method is that the method comprises:

[0079] During the blood pressure reduction process of blood pressure measurement, the pulse sequence corresponding to the target pressure is obtained. When the maximum amplitude appears, if the number of current pulse sequences is less than the preset threshold, the pressure is adjusted to the next target pressure and then the pulse sequence is continued to be obtained. Then, it is determined whether the number of current pulse sequences is less than the preset threshold. The above adjustment steps are repeated until a sufficient number of amplitude sequences are obtained.

[0080] After obtaining a sufficient number of pulse sequences, atrial fibrillation is judged, and a difference sequence of pulse intervals is calculated based on the obtained multiple pulse amplitude sequences to determine whether atrial fibrillation exists, and the difference sequence is divided into multiple small sequences to determine whether atrial fibrillation exists.

[0081] In the atrial fibrillation detection method based on single measurement and multiple pressurization, in order to obtain a sufficient number of correct pulse sequences, during the depressurization process of blood pressure measurement, the pulse sequence corresponding to the target pressure is obtained. When the maximum amplitude appears, if the current number of pulse sequences is less than the preset threshold, the pressurization is adjusted to the next target pressure and the pulse sequence is continued to be obtained. Then it is determined whether the current number of pulse sequences is less than the preset threshold. The above adjustment steps are repeated until a sufficient number of amplitude sequences are obtained, until a sufficient number of pulse waves are detected, so that sufficient data can be obtained during the depressurization process of a single blood pressure measurement to make an atrial fibrillation judgment, without requiring the user to experience the pressurization and depressurization process of multiple blood pressure measurements, thereby avoiding user discomfort and reducing the time for atrial fibrillation judgment. In addition, in the method of continuing to obtain the pulse sequence after adjusting the pressurization to the next target pressure, when multiple pressurizations are performed during the depressurization process, it is not necessary to pressurize to the first target pressure value, and the pressurization time can be adjusted. One step is shortened, which can improve the user experience; in the step of judging the presence of atrial fibrillation by the difference sequence, the pulse interval difference sequence is calculated according to the multiple pulse interval sequences obtained, and the pulse interval difference sequence is used to judge whether the change of the pulse sequence is greater than the pulse change threshold, so as to further ensure the accuracy and reference of the multiple pulse interval sequence data obtained, so as to provide data guarantee for subsequent judgments and avoid the occurrence of misjudgments; in the step of judging the presence of atrial fibrillation by the small sequence, the pulse interval difference sequence is evenly distributed into multiple small sequences, and then each small sequence is judged and counted, so as to further achieve the purpose of using the data obtained in the decompression process of a single blood pressure measurement to judge the presence of atrial fibrillation, and the process more accurately and finely judges the "digital information" presented in the pulse amplitude signal sequence corresponding to atrial fibrillation, so as to further avoid misjudgment of atrial fibrillation.

[0082] In the first embodiment of the present invention, the next target pressure is adjusted by one or both of the following methods:

[0083] The preset target pressure value is used; the next target pressure is calculated according to the pulse sequence of the pulse. In this way, the next target pressure can be adjusted flexibly, and there are more options for interference or other problems in blood pressure measurement, so as to ensure that a sufficient number of pulse sequences can be obtained, the data can be correct, and the time for multiple pressurization can be shortened.

[0084] In the first embodiment of the present invention, in the method of calculating the next target pressure according to the pulse sequence of the pulse, the number of pulse sequences to be detected is calculated through the preset threshold of the pulse sequence and the number of currently detected pulse sequences. By judging that the number of pulse sequences from the end of deflation point to the target pressure value is equal to the number of pulse sequences to be detected, a suitable next target pressure is selected, so as to determine the next target pressure in a scientific and reasonable manner, so that the time required for multiple pressurization operations can be shortened, and the feeling of multiple pressurization applied to the user can be better.

[0085] In the first embodiment of the present invention, for the selection of a suitable next target, it is defined that the deflation speed of the deflation valve is V, the pressure at the end of deflation point is P0, the number of pulse sequences to be detected is N, and the pulse rate value of the measured person is PR. The suitable next target pressure value P satisfies: (P - P0) / V = N / PR, that is, P = (N / PR)*V + P0. In this way, a more scientific and reasonable way is used to obtain a suitable next target pressure value, so that the pressure control of multiple pressurizations is more in line with the current user's pulse rate, and the next target pressure can be adjusted according to the pulse rate conditions of different users themselves. Different adjustment methods can be used for the judgment of atrial fibrillation during blood pressure measurement for different users and different situations, so as to expand the applicable user population.

[0086] In the first embodiment of the present invention, the maximum amplitude of the obtained pulse sequence Ai is searched. i is a positive integer from 1 to n, representing the position of the pulse sequence on the time axis. The maximum amplitude is denoted as Amax. A maximum amplitude judgment adjustment coefficient R and a maximum amplitude judgment times threshold Nr are set. If the number of amplitudes Ai < Amax*R after the maximum amplitude is greater than or equal to Nr, it means that the maximum amplitude appears and the slow deflation ends. After the maximum amplitude appears, it is determined whether the number of obtained pulse sequences k is less than the preset threshold. If it is greater, this blood pressure measurement ends; if it is less, the loop is repeated. Through the implementation of this step, through the accurate and reliable confirmation of the maximum amplitude, the accuracy and referenceability of the number of obtained amplitude sequences are further guaranteed, so as to provide data guarantee for subsequent judgments and avoid misjudgments. More specifically, R takes a value of 0.2 to 1.0, and Nr ≥ 1. For example, R can take 0.7 and Nr can take 3, so that the values of the maximum amplitude judgment adjustment coefficient R and the maximum amplitude judgment times threshold Nr are more reasonable, and the time spent in the decompression process of a single blood pressure measurement and the number of pulse sequences to be obtained can be balanced.

[0087] In the first embodiment of the present invention, the adjustment step of continuing to acquire the pulse sequence after adjusting the pressurization to the next target pressure and then determining whether the current number of amplitude sequences is less than a preset threshold is subject to a loop limit. The loop limit is limited to a limited number of times. When the limited number of times is reached, the loop is forced to end, and atrial fibrillation is determined based on all the pulse sequences that have been acquired, thereby avoiding excessive loop times and excessively long atrial fibrillation time, and further improving the user experience.

[0088] In the first embodiment of the present invention, the step of calculating the difference sequence of pulse intervals based on the acquired multiple pulse amplitude sequences to determine whether atrial fibrillation exists includes the following steps:

[0089] Calculate pulse interval difference sequence;

[0090] Calculate the average interval change and average interval of the pulse interval sequence;

[0091] Calculate the average change of the pulse interval sequence and the overall change of the pulse interval sequence;

[0092] The pulse change thresholds set include an average threshold and an overall threshold, and it is determined whether the average change of the pulse interval sequence is greater than the average threshold and the overall change of the pulse interval sequence is greater than the overall threshold;

[0093] If the answer is no, it is determined that atrial fibrillation does not exist. If the answer is yes, it is determined that atrial fibrillation exists and the difference sequence is divided into a plurality of small sequences to determine whether atrial fibrillation exists.

[0094] Through the implementation of this step, the pulse interval difference sequence is calculated based on the multiple pulse interval sequences obtained, and the pulse interval difference sequence is used to determine whether the change in the pulse sequence is greater than the pulse change threshold, thereby further ensuring the accuracy and referenceability of the multiple pulse interval sequence data obtained, thereby providing data guarantee for subsequent judgments and avoiding the occurrence of misjudgments.

[0095] In the first embodiment of the present invention, the step of calculating the difference sequence of pulse intervals based on the acquired multiple pulse amplitude sequences to determine whether atrial fibrillation exists includes the following steps:

[0096] Calculate the pulse interval difference sequence Ri, where Ri = (ΔAi+1)-(ΔAi);

[0097] The average interval change St is calculated by the pulse interval difference sequence Ri, Where n is the number of pulse interval difference sequences Ri; the average interval amount Sr is calculated by the pulse interval difference sequence Ri,

[0098] Calculate the average change of the pulse interval sequence ΔS, ΔS = St / Sr; calculate the overall change of the pulse interval sequence ΔD,

[0099] The pulse change thresholds set include an average threshold ΔSk and an overall threshold ΔDk, and it is judged whether the average change ΔS is greater than the average threshold ΔSk and the overall change ΔD is greater than the overall threshold ΔDk, where ΔSk and ΔDk are both greater than 0;

[0100] If ΔS>ΔSk and ΔD>ΔDk cannot be satisfied simultaneously, it is judged that atrial fibrillation does not exist. If ΔS>ΔSk and ΔD>ΔDk are satisfied simultaneously, it is judged that atrial fibrillation exists and the difference sequence is distributed into multiple small sequences to determine whether atrial fibrillation exists.

[0101] Through the implementation of this step, the application settings of algorithms and parameters are reasonable and scientific, and the steps and applications therein can provide data guarantee for subsequent judgments.

[0102] In the first embodiment of the present invention, the step of determining whether atrial fibrillation exists after allocating the difference sequence into a plurality of small sequences includes the following steps:

[0103] Evenly distribute the pulse interval difference sequence into multiple small sequences;

[0104] Calculate the average change of each small sequence and the overall change of each small sequence respectively;

[0105] Determine whether the average change of the small sequence is greater than the average threshold and the overall change of the small sequence is greater than the overall threshold;

[0106] If both the average change of the small sequence is greater than the average threshold and the overall change of the small sequence is greater than the overall threshold, the sequence result of the small sequence is counted; if not, it is not counted;

[0107] Calculate sequence results and values;

[0108] Determine whether the sequence result and value are greater than the result setting value;

[0109] If the sum of the sequence results is greater than the result setting value, it is determined that atrial fibrillation exists; if the sum of the sequence results is less than the result setting value, atrial fibrillation does not exist.

[0110] By implementing this step, the purpose of using the data obtained during the decompression process of a single blood pressure measurement to determine the presence of atrial fibrillation is further achieved, and this process more accurately and finely determines the "digital information" presented in the pulse amplitude signal sequence corresponding to atrial fibrillation, thereby further avoiding misjudgment of atrial fibrillation.

[0111] In the first embodiment of the present invention, the step of determining whether atrial fibrillation exists after allocating the difference sequence into a plurality of small sequences includes the following steps:

[0112] The pulse interval difference sequence is evenly divided into m small sequences;

[0113] Calculate the average change ΔSj of each small sequence and the overall change ΔDj of each small sequence respectively, where j ranges from 1 to m;

[0114] Determine whether the average change ΔSj of the small sequence is greater than the average threshold ΔSk and the overall change ΔDj of the small sequence is greater than the overall threshold ΔDk;

[0115] If the average change ΔSj of the small sequence is greater than the average threshold ΔSk and the overall change ΔDj of the small sequence is greater than the overall threshold ΔDk, the sequence result of the small sequence is counted as 1, otherwise, it is not counted;

[0116] Calculate sequence results and values;

[0117] Determine whether the sequence result and value are greater than the result setting value C, where C ranges from 1 to m;

[0118] If the sum of the sequence results is greater than the result setting value, it is determined that atrial fibrillation exists; if the sum of the sequence results is less than the result setting value, atrial fibrillation does not exist.

[0119] Through the implementation of this step, the numerical value setting is reasonable and scientific, the pulse interval sequence obtained by a single blood pressure measurement can be used for judgment, and misjudgment can be avoided.

[0120] The first embodiment of the present invention is further described below with reference to one of the preferred embodiments in more detail.

[0121] The method for detecting atrial fibrillation by blood pressure measurement based on dynamic deflation in this preferred embodiment includes the following detailed steps.

[0122] During the blood pressure reduction process of blood pressure measurement, a pulse sequence corresponding to the target pressure is obtained. When the maximum amplitude appears and the current number of pulse sequences is less than the preset threshold, the pressurization is adjusted to the next target pressure and then the pulse sequence is continuously obtained. Among them, the maximum amplitude of the obtained pulse sequence Ai is searched, where i is a positive integer from 1 to n, representing the position of the pulse sequence on the time axis, and the maximum amplitude is denoted as Amax. The maximum amplitude judgment adjustment coefficient R and the maximum amplitude judgment number threshold Nr are set. If the number of Ai < Amax * R after the maximum amplitude is greater than or equal to Nr, it indicates that the maximum amplitude appears. Among them, in the method of calculating the next target pressure based on the pulse sequence of the pulse, the number of pulse sequences that still need to be detected is calculated through the preset threshold of the pulse sequence and the current number of detected pulse sequences. The appropriate next target pressure is selected by judging that the number of pulse sequences from the end of the deflation point to the target pressure value is equal to the number of pulse sequences that still need to be detected. For the selection of the appropriate next target, where the deflation speed of the deflation valve is defined as V, the pressure at the end of the deflation point is P0, the number of pulse sequences that still need to be detected is N, and the pulse rate value of the被测者 is PR, the appropriate next target pressure value P satisfies: (P - P0) / V = N / PR, that is, P = (N / PR) * V + P0; then it is determined whether the current number of pulse sequences is less than the preset threshold, and the above adjustment steps are repeated in a loop until a sufficient number of amplitude sequences are obtained; the adjustment step of adjusting the pressurization to the next target pressure and then continuing to obtain the pulse sequence and then determining whether the current number of amplitude sequences is less than the preset threshold is used as a loop limit, and the loop limit is a finite number of times. When the finite number of times is reached, the loop is forced to end, and atrial fibrillation is judged based on all the obtained pulse sequences.

[0123] After obtaining a sufficient number of pulse sequences, atrial fibrillation is judged. In the step of calculating the difference sequence of the pulse intervals based on the obtained multiple pulse amplitude sequences to determine whether there is atrial fibrillation, the following steps are included:

[0124] Calculate the difference sequence of the pulse intervals;

[0125] Calculate the average interval change amount and the average interval amount of the pulse interval sequence;

[0126] Calculate the average change amount of the pulse interval sequence and the overall change amount of the pulse interval sequence;

[0127] The set pulse change thresholds include an average threshold and an overall threshold. It is judged whether the average change amount of the pulse interval sequence is greater than the average threshold and the overall change amount of the pulse interval sequence is greater than the overall threshold;

[0128] If not, it is judged that atrial fibrillation does not exist. If so, it is judged that atrial fibrillation exists and the step of dividing the difference sequence into multiple small sequences and then judging whether there is atrial fibrillation is carried out.

[0129] The step of determining whether atrial fibrillation exists after allocating the difference sequence into a plurality of small sequences includes the following steps:

[0130] Evenly distribute the pulse interval difference sequence into multiple small sequences;

[0131] Calculate the average change of each small sequence and the overall change of each small sequence respectively;

[0132] Determine whether the average change of the small sequence is greater than the average threshold and the overall change of the small sequence is greater than the overall threshold;

[0133] If both the average change of the small sequence is greater than the average threshold and the overall change of the small sequence is greater than the overall threshold, the sequence result of the small sequence is counted; if not, it is not counted;

[0134] Calculate sequence results and values;

[0135] Determine whether the sequence result and value are greater than the result setting value;

[0136] If the sum of the sequence results is greater than the result setting value, it is determined that atrial fibrillation exists; if the sum of the sequence results is less than the result setting value, atrial fibrillation does not exist.

[0137] Embodiment 2, as Figure 1 , Figure 2 As shown, the second embodiment of the present invention proposes a blood pressure measurement device, which is used for the blood pressure measurement in the method of the first embodiment of the present invention to determine the presence of atrial fibrillation. The device includes a main control unit, a display unit, a pressurizing unit, a decompressing unit, a pressure pulse detection unit and an atrial fibrillation determination unit;

[0138] The pressure pulse detection unit is used to obtain the pulse sequence corresponding to the target pressure and transmit it to the main control unit for calculation and processing;

[0139] The main control unit is electrically connected to the display unit, the pressure pulse detection unit, the atrial fibrillation judgment unit, the pressurization unit and the decompression unit. The main control unit controls the pressurization unit to pressurize to a preset target pressure, and then controls the decompression unit to slowly reduce the pressure. In a single decompression process of slowly reducing the pressure, a sufficient number of pulse interval sequences are obtained, and when the maximum amplitude appears, if the current number of amplitude sequences is less than a preset threshold, the pressurization is adjusted to the next target pressure and the pulse sequence is continued to be obtained, and then it is determined whether the current number of pulse sequences is less than the preset threshold, and the above adjustment steps are repeated until a sufficient number of amplitude sequences are obtained;

[0140] The atrial fibrillation determination unit determines atrial fibrillation after acquiring a sufficient number of amplitude sequences, so as to finally determine whether atrial fibrillation exists;

[0141] The pressurizing unit is used to control the pressurization of the cuff airbag, pressurize the cuff airbag to a target pressure, and accept the control of the main control unit to adjust the pressurization to the next target pressure;

[0142] The decompression part is used to slowly deflate the cuff airbag during the decompression process;

[0143] The display unit is used to display the blood pressure result calculated by the main control unit, the atrial fibrillation result determined by the atrial fibrillation determination unit, and the status information of the measurement process.

[0144] Embodiment three, embodiment three of the present invention further proposes a readable storage medium, on which a control program is stored. When the control program is executed by a main control unit, the main control unit executes the steps of the atrial fibrillation detection method based on single measurement and multiple pressurization as described in embodiment one of the present invention.

[0145] Embodiment 4, Embodiment 4 of the present invention further proposes a method for measuring blood pressure using a blood pressure measuring device and determining whether atrial fibrillation exists during the blood pressure measurement, wherein the blood pressure measuring device includes a main control unit, a pressurizing unit, a decompressing unit, a pressure pulse detection unit and an atrial fibrillation determination unit;

[0146] The pressure pulse detection unit is used to obtain the pulse sequence corresponding to the target pressure and transmit it to the main control unit for calculation and processing;

[0147] The main control unit is electrically connected to the display unit, the pressure pulse detection unit, the atrial fibrillation judgment unit, the pressurization unit and the decompression unit. The main control unit controls the pressurization unit to pressurize to a preset target pressure, and then controls the decompression unit to slowly reduce the pressure. In a single decompression process of slowly reducing the pressure, a sufficient number of pulse interval sequences are obtained, and when the maximum amplitude appears, if the current number of amplitude sequences is less than a preset threshold, the pressurization is adjusted to the next target pressure and the pulse sequence is continued to be obtained, and then it is determined whether the current number of pulse sequences is less than the preset threshold, and the above adjustment steps are repeated until a sufficient number of amplitude sequences are obtained;

[0148] The atrial fibrillation determination unit determines atrial fibrillation after acquiring a sufficient number of amplitude sequences, so as to finally determine whether atrial fibrillation exists;

[0149] The pressurizing unit is used to control the pressurization of the cuff airbag, pressurize the cuff airbag to a target pressure, and accept the control of the main control unit to adjust the pressurization to the next target pressure;

[0150] The decompression part is used to slowly deflate the cuff airbag during the decompression process;

[0151] The method comprises:

[0152] During the blood pressure reduction process of blood pressure measurement, the pulse sequence corresponding to the target pressure is obtained. When the maximum amplitude appears, if the number of current pulse sequences is less than the preset threshold, the pressure is adjusted to the next target pressure and then the pulse sequence is continued to be obtained. Then, it is determined whether the number of current pulse sequences is less than the preset threshold. The above adjustment steps are repeated until a sufficient number of amplitude sequences are obtained.

[0153] After obtaining a sufficient number of pulse sequences, atrial fibrillation is judged, and a difference sequence of pulse intervals is calculated based on the obtained multiple pulse amplitude sequences to determine whether atrial fibrillation exists, and the difference sequence is divided into multiple small sequences to determine whether atrial fibrillation exists.

[0154] Combine the following Figures 1 to 7 The contents shown illustrate the structure and working principle of the present invention.

[0155] Figure 1 FIG. 1 shows the appearance of a blood pressure measuring device according to an embodiment of the present invention. The blood pressure measuring device generally comprises a blood pressure measuring cuff wrapped around a measuring part of a subject and a sphygmomanometer body connected to the cuff. The blood pressure measuring device comprises a main control unit, a display unit, a pressurizing unit, a decompressing unit, an atrial fibrillation determining unit, and a pressure pulse detecting unit.

[0156] Figure 2 As shown, the outline composition of the blood pressure measuring device is shown. The main control unit is electrically connected to the display unit, the pressure pulse detection unit, the pressurizing part and the decompression part. The main control unit controls the pressurizing part to pressurize to a preset pressure, and then controls the decompression part to slowly reduce the pressure. In the process of slow pressure reduction, the pressure pulse detection unit obtains pulse wave signals corresponding to multiple target pressures. When the main control unit determines that the slow deflation is over, it further determines whether the current number of pulse sequences is less than a preset threshold. If it is less, the target pressure value for the next pressurization is determined based on the detected pulse sequence and the initial pressurization height. After pressurizing to this pressure value, pulse signal detection is continued. When it is determined again that the slow deflation is over, the judgment of the number of pulse sequences and the pressurization target pressure value is repeated. The number of cycles is limited. When the set limited number of cycles is reached, the cycle is forced to end. When a sufficient number of pulse sequences are detected, the atrial fibrillation detection unit determines whether atrial fibrillation exists based on the characteristics of the pulse sequence.

[0157] The pressurizing unit is used to control the pressurization of the cuff airbag, and by cooperating with the pressure pulse detection unit, the cuff airbag is pressurized to a preset pressure.

[0158] The pressure pulse detection unit is used to detect the pressure in the cuff airbag during the pressurization and decompression process, and simultaneously obtain the pulse wave signals corresponding to multiple target pressures and transmit them to the main control unit for calculation and processing.

[0159] The decompression unit is used to slowly deflate the cuff balloon during the blood pressure measurement under reduced pressure and quickly deflate it at the end of the measurement.

[0160] The display unit is used to display the blood pressure result calculated by the main control unit and the status information of the measurement process.

[0161] Next, the working principle of the solution of the present invention will be described:

[0162] During the slow deflation process of the decompression unit, the pressure pulse detection unit acquires the pulse signals corresponding to multiple target pressures. The main control unit determines whether the slow deflation ends based on the detected pulse signals. The determination method can be: searching for the maximum amplitude of the pulse sequence Ai, where i is a positive integer from 1 to k, representing the position of the pulse sequence on the time axis, and the maximum amplitude is denoted as Amax, and max represents the position of the maximum amplitude. If the number of occurrences of Ai < Amax * R after the maximum amplitude is greater than or equal to Nr (R ranges from 0.2 to 1.0, and Nr ≥ 1), it indicates that the slow deflation ends. At this time, the main control unit determines whether the number k of the pulse sequences is less than the preset threshold. If it is less, the main control unit controls the pressurization unit to pressurize to the target pressure value Po. The target pressure value can be the preset pressure value for the first pressurization or a suitable target pressure value selected through the pulse sequence. The suitable target pressure value can be calculated by the number of threshold values of the pulse sequence and the number of currently detected pulse sequences to obtain the number of pulse sequences that still need to be detected, and a suitable target pressure value is selected by determining that the number of pulse sequences from the end deflation point to this target pressure value is equal to the number of pulse sequences that still need to be detected. After pressurizing to the target pressure value, continue to detect the pulse signal. When it is determined again that the slow deflation ends, continue to repeat the judgment of the number of pulse sequences and the target pressure value. This loop is set to a finite number of times, and when the set finite loop times are reached, the loop is forced to end. Figure 3 Shows the flowchart of multiple pressurization judgments.

[0163] After the measurement ends, further calculations are performed based on the pulse amplitude sequence Ai, where i is a positive integer from 1 to n, representing the position of the waveform sequence on the time axis. Calculate the pulse interval sequence ΔAi = (Ai + 1) - (Ai) from 1 to n - 1, and calculate the average value Sa of the ΔAi sequence. Take Sk1 = k1 * Sa (Sk1 is the judgment threshold for the selected lower interval limit, and k1 ranges from 0.5 to 0.9), take Sk2 = k2 * Sa (Sk2 is the judgment threshold for the selected upper interval limit, and k2 ranges from 1.1 to 1.5), and perform upper and lower limit judgments on the elements in the pulse interval sequence ΔAi, and record the number N of elements exceeding the upper and lower limit thresholds. If N ≥ Nk (Nk is the irregular pulse number threshold, and the value range is Nk ≥ 2), it indicates that atrial fibrillation may occur. Figure 4 Shows the flowchart of pulse waveform detection and judgment.

[0164] Further calculate the pulse interval difference sequence Ri = (ΔAi+1)-(ΔAi), and calculate the average interval change through the Ri sequence (n is the number of Ri sequences), the average interval is calculated by the ΔAi sequence The average change of the pulse sequence ΔS = St / Sr, the overall change of the pulse sequence Take the threshold ΔSk of the average change of the pulse sequence and the threshold ΔDk of the overall change of the pulse sequence (ΔSk and ΔDk are both greater than 0). If ΔS>ΔSk and ΔD>ΔDk are satisfied at the same time, it indicates the presence of atrial fibrillation. Figure 5 A flow chart for determining the presence of atrial fibrillation is shown. Figure 7 The characteristic points of the measurement process are shown.

[0165] The difference sequence of the pulse signal is evenly distributed into m small sequences, and the average pulse change rate ΔSj and the overall pulse change ΔDj (the value of j ranges from 1 to m) of each small sequence are calculated respectively. If the small sequence satisfies ΔSj>ΔSk and ΔDj>ΔDk at the same time, the result is recorded as 1, otherwise it is recorded as 0. If the sum of all sequence results is greater than C (the value of C ranges from 1 to m), atrial fibrillation is judged to exist. Figure 6 A flow chart showing a small sequence for determining the presence of atrial fibrillation.

[0166] By implementing the above embodiments and applying the above atrial fibrillation detection method and device based on single measurement and multiple pressurization, it is possible to obtain sufficient pulse interval sequence data during the decompression process of a single blood pressure measurement to perform difference sequence judgment on the presence of atrial fibrillation and small sequence judgment on the presence of atrial fibrillation. The multiple pressurization time can be further shortened, and the additional time added while obtaining sufficient pulse sequences will not be too long, thereby providing a better user experience, and ensuring the accuracy and reference of the multiple pulse interval sequence data obtained, providing data guarantee for the judgment result of atrial fibrillation, avoiding misjudgment, and achieving the purpose of the present invention.

[0167] The above embodiments are only for illustrating the technical concept and features of the present invention, and their purpose is to enable people familiar with the technology to understand the content of the present invention and implement it accordingly, and they cannot be used to limit the protection scope of the present invention. Any equivalent changes or modifications made according to the spirit of the present invention should be included in the protection scope of the present invention.

Claims

1. A method for detecting atrial fibrillation based on single measurement and multiple pressurization, used to determine whether atrial fibrillation exists during blood pressure measurement, characterized in that: The method includes: During the blood pressure reduction process of blood pressure measurement, obtain the pulse sequence corresponding to the target pressure. When the maximum amplitude appears and the current number of pulse sequences is less than the preset threshold, adjust the pressure to the next target pressure and then continue to obtain the pulse sequence, and then determine whether the current number of pulse sequences is less than the preset threshold. Repeat the above adjustment steps in a loop until a sufficient number of amplitude sequences are obtained; After obtaining a sufficient number of pulse sequences, perform atrial fibrillation judgment. Calculate the difference sequence of pulse intervals based on the obtained multiple pulse amplitude sequences to determine whether there is atrial fibrillation, and divide the difference sequence into multiple small sequences and then determine whether there is atrial fibrillation.

2. The atrial fibrillation detection method based on single measurement and multiple pressurization according to claim 1, characterized in that: The adjustment of the next target pressure adopts one or both of the following methods: Adopt the preset target pressure value; Calculate the next target pressure according to the pulse sequence of the pulse.

3. The atrial fibrillation detection method based on single measurement and multiple pressurization according to claim 2, characterized in that: In the method of calculating the next target pressure according to the pulse sequence of the pulse, calculate the number of pulse sequences that still need to be detected through the preset threshold of the pulse sequence and the current number of detected pulse sequences, and select the appropriate next target pressure by judging that the number of pulse sequences from the end of deflation point to this target pressure value is equal to the number of pulse sequences that still need to be detected.

4. The atrial fibrillation detection method based on single measurement and multiple pressurization according to claim 3, characterized in that: For the selection of the appropriate next target, where the deflation speed of the deflation valve is defined as V, the pressure at the end of deflation is P0, the number of pulse sequences that still need to be detected is N, and the pulse rate value of the measured person is PR, the appropriate next target pressure value P satisfies: (P - P0) / V = N / PR, that is, P = (N / PR)*V + P0.

5. The atrial fibrillation detection method based on single measurement and multiple pressurization according to claim 1, characterized in that: Search for the maximum amplitude of the obtained pulse sequence Ai. i is a positive integer from 1 to n, representing the position of the pulse sequence on the time axis. The maximum amplitude is denoted as Amax. Set the maximum amplitude judgment adjustment coefficient R and the maximum amplitude judgment number threshold Nr. If the number of amplitudes Ai < Amax*R after the maximum amplitude is greater than or equal to Nr, it means that the maximum amplitude appears and the slow deflation ends. After the maximum amplitude appears, determine whether the number k of the obtained pulse sequences is less than the preset threshold. If it is greater, end this blood pressure measurement. If it is less, repeat the loop.

6. The atrial fibrillation detection method based on single measurement and multiple pressurization according to claim 5, characterized in that: Make a loop limit for the adjustment step of adjusting the pressure to the next target pressure and then continuing to obtain the pulse sequence and then determining whether the current number of amplitude sequences is less than the preset threshold. The loop limit is a finite number of times. When the finite number of times is reached, force the end of the loop, and perform atrial fibrillation judgment based on all the obtained pulse sequences.

7. The atrial fibrillation detection method based on single measurement and multiple pressurization according to claim 1, characterized in that: In the step of calculating the difference sequence of pulse intervals based on the obtained multiple pulse amplitude sequences to determine whether there is atrial fibrillation, the following steps are included: Calculate the difference sequence of pulse intervals; Calculate the average interval change amount and average interval amount of the pulse interval sequence; Calculate the average change amount of the pulse interval sequence and the overall change amount of the pulse interval sequence; The set pulse change thresholds include an average threshold and an overall threshold. Determine whether the average change amount of the pulse interval sequence is greater than the average threshold and the overall change amount of the pulse interval sequence is greater than the overall threshold; If the answer is no, it is determined that atrial fibrillation does not exist. If the answer is yes, it is determined that atrial fibrillation exists and the difference sequence is divided into a plurality of small sequences to determine whether atrial fibrillation exists.

8. The atrial fibrillation detection method based on single measurement and multiple pressurization according to claim 9, characterized in that: The step of calculating a pulse interval difference sequence based on a plurality of acquired pulse amplitude sequences to determine whether atrial fibrillation exists includes the following steps: Calculate the pulse interval difference sequence Ri, where Ri = (ΔAi+1)-(ΔAi); The average interval change St is calculated by the pulse interval difference sequence Ri, Where n is the number of pulse interval difference sequences Ri; the average interval amount Sr is calculated by the pulse interval difference sequence Ri, Calculate the average change of the pulse interval sequence ΔS, ΔS = St / Sr; calculate the overall change of the pulse interval sequence ΔD, The pulse change thresholds set include an average threshold ΔSk and an overall threshold ΔDk, and it is judged whether the average change ΔS is greater than the average threshold ΔSk and the overall change ΔD is greater than the overall threshold ΔDk, where ΔSk and ΔDk are both greater than 0; If ΔS>ΔSk and ΔD>ΔDk cannot be satisfied simultaneously, it is judged that atrial fibrillation does not exist. If ΔS>ΔSk and ΔD>ΔDk are satisfied simultaneously, it is judged that atrial fibrillation exists and the difference sequence is distributed into multiple small sequences to determine whether atrial fibrillation exists.

9. The atrial fibrillation detection method based on single measurement and multiple pressurization according to claim 8, characterized in that: The step of determining whether atrial fibrillation exists after allocating the difference sequence into a plurality of small sequences includes the following steps: Evenly distribute the pulse interval difference sequence into multiple small sequences; Calculate the average change of each small sequence and the overall change of each small sequence respectively; Determine whether the average change of the small sequence is greater than the average threshold and the overall change of the small sequence is greater than the overall threshold; If both the average change of the small sequence is greater than the average threshold and the overall change of the small sequence is greater than the overall threshold, the sequence result of the small sequence is counted; if not, it is not counted; Calculate sequence results and values; Determine whether the sequence result and value are greater than the result setting value; If the sum of the sequence results is greater than the result setting value, it is determined that atrial fibrillation exists; if the sum of the sequence results is less than the result setting value, atrial fibrillation does not exist.

10. The atrial fibrillation detection method based on single measurement and multiple pressurization according to claim 9, characterized in that: The step of determining whether atrial fibrillation exists after allocating the difference sequence into a plurality of small sequences includes the following steps: The pulse interval difference sequence is evenly divided into m small sequences; Calculate the average change ΔSj of each small sequence and the overall change ΔDj of each small sequence respectively, where j ranges from 1 to m; Determine whether the average change ΔSj of the small sequence is greater than the average threshold ΔSk and the overall change ΔDj of the small sequence is greater than the overall threshold ΔDk; If the average change ΔSj of the small sequence is greater than the average threshold ΔSk and the overall change ΔDj of the small sequence is greater than the overall threshold ΔDk, the sequence result of the small sequence is counted as 1, otherwise, it is not counted; Calculate sequence results and values; Determine whether the sequence result and value are greater than the result setting value C, where C ranges from 1 to m; If the sum of the sequence results is greater than the result setting value, it is determined that atrial fibrillation exists; if the sum of the sequence results is less than the result setting value, atrial fibrillation does not exist.

11. A blood pressure measuring device, characterized in that: The device includes a main control unit, a display unit, a pressurizing unit, a decompressing unit, a pressure pulse detection unit and an atrial fibrillation determination unit; wherein, The pressure pulse detection unit is used to obtain the pulse sequence corresponding to the target pressure and transmit it to the main control unit for calculation and processing; The main control unit is electrically connected to the display unit, the pressure pulse detection unit, the atrial fibrillation judgment unit, the pressurization unit and the decompression unit. The main control unit controls the pressurization unit to pressurize to a preset target pressure, and then controls the decompression unit to slowly reduce the pressure. In a single decompression process of slowly reducing the pressure, a sufficient number of pulse interval sequences are obtained, and when the maximum amplitude appears, if the current number of amplitude sequences is less than a preset threshold, the pressurization is adjusted to the next target pressure and the pulse sequence is continued to be obtained, and then it is determined whether the current number of pulse sequences is less than the preset threshold, and the above adjustment steps are repeated until a sufficient number of amplitude sequences are obtained; The atrial fibrillation determination unit determines atrial fibrillation after acquiring a sufficient number of amplitude sequences, so as to finally determine whether atrial fibrillation exists; The pressurizing unit is used to control the pressurization of the cuff airbag, pressurize the cuff airbag to a target pressure, and accept the control of the main control unit to adjust the pressurization to the next target pressure; The decompression part is used to slowly deflate the cuff airbag during the decompression process; The display unit is used to display the blood pressure result calculated by the main control unit, the atrial fibrillation result determined by the atrial fibrillation determination unit, and the status information of the measurement process.

12. A readable storage medium, characterized in that: The readable storage medium stores a control program, and when the control program is executed by the main control unit, the main control unit executes the steps of the method according to any one of claims 1 to 10.

Images