Atomized liquid, atomizer and electronic atomization device

Abstract

The invention discloses atomized liquid, an atomizer and an electronic atomization device. The atomized liquid comprises 65 wt%-99.65 wt% of a solvent, 0.1 wt%-5 wt% of a nicotine substitute and 0.25 wt%-30 wt% of a flavoring agent, the nicotine substitute is selected from at least one of 6-alkyl nicotine and a salt of 6-alkyl nicotine, and the alkyl group has 1-4 carbon atoms. The irritation of the substitute of nicotine in the atomized liquid is reduced, the taste is close to that of traditional tobacco, and the satisfaction is improved.

Description

Technical Field

[0001] The present invention belongs to the technical field of electronic atomization, and in particular relates to an atomizing liquid, an atomizer and an electronic atomizing device. Background Art

[0002] Nicotine, also known as nicotine, is the main active ingredient in tobacco and the key ingredient in current electronic atomization devices that can make consumers feel satisfied and happy. However, nicotine is highly addictive and has some potential harm to human health, so reducing the nicotine concentration in atomization liquid has become a global policy and regulatory trend. Atomization liquid with low nicotine concentration cannot make consumers feel satisfied, so it is of great significance to develop low-harm atomization liquid that can meet consumers' needs for satisfaction on the existing basis.

[0003] Some nicotine derivatives have better affinity for nicotinic acetylcholine receptors than nicotine, and have less toxic side effects, and can be used as nicotine substitutes. However, these nicotine substitutes have problems such as strong irritation to the mouth and throat, and a taste that is very different from traditional tobacco, which affects the user's smoking experience.

[0004] Therefore, it is necessary to provide an improved atomizing liquid. Summary of the invention

[0005] In view of this, the main purpose of the present disclosure is to provide an atomizing liquid. The irritation of the nicotine substitute in the atomizing liquid is reduced, the mouthfeel is close to that of traditional tobacco, and the satisfaction is improved. A further purpose of the present application is to provide an atomizer and an electronic atomizing device containing the atomizing liquid.

[0006] In order to achieve the above objectives, the present disclosure provides the following technical solutions.

[0007] A first aspect of the present disclosure provides an atomizing liquid, comprising: 65 wt%-99.65 wt% of a solvent, 0.1 wt%-5 wt% of a nicotine substitute, and 0.25 wt%-30 wt% of a flavorant, wherein the nicotine substitute is at least one selected from 6-alkyl nicotine and a salt of 6-alkyl nicotine, and the alkyl group is an alkyl group having 1 to 4 carbon atoms.

[0008] According to one embodiment of the present disclosure, the flavoring agent includes furfuryl acetate, 6-isopropylquinoline and 2-methyl-3-ethylmaleimide.

[0009] According to an embodiment of the present disclosure, based on the weight of the atomization liquid, the flavoring agent includes 0.1% to 3% by weight of furfuryl acetate, 0.05% to 2% by weight of 6-isopropylquinoline, and 0.1% to 2% by weight of 2-methyl-3-ethylmaleimide; preferably, the flavoring agent includes 1.0% to 1.5% by weight of furfuryl acetate, 0.5% to 1.5% by weight of 6-isopropylquinoline, and 0.5% to 1.5% by weight of 2-methyl-3-ethylmaleimide.

[0010] According to an embodiment of the present disclosure, the flavoring agent further includes at least one of 2-isobutyl-1,3-thiazole, N-(3-methylbutyl)pyrrolidine, N-(3-methylbutyl)acetamide, 2-piperidone, pyrrolidin-2-one, diethylmaleimide, 2-ethylidene-3-methylmaleimide, 2-ethyl-3-methylsuccinimide, N-methylsuccinimide, 2-isopropenylisophorone, 2,3-dimethyl-4-hydroxy-6-oxooctanoate, and 5-isopropyl-2-methylpyrazine.

[0011] According to an embodiment of the present disclosure, the 6-alkyl nicotine is 6-methyl nicotine and / or 6-ethyl nicotine, and the salt is at least one selected from benzoate, malate, tartrate, citrate, acetylpropionate, and lactate.

[0012] According to an embodiment of the present disclosure, based on the weight of the atomization liquid, the atomization liquid includes 0.5% to 1.5% by weight of nicotine substitute; preferably, the atomization liquid includes 0.5% to 1.0% by weight of nicotine substitute.

[0013] According to an embodiment of the present disclosure, the solvent is at least one selected from water, ethanol, ethylene glycol, propanol, propylene glycol, glycerol, butanol, butylene glycol, butanetriol, benzyl alcohol, triethyl citrate, glyceryl triacetate, and caprylic / capric triglyceride; preferably, the solvent includes glycerol and propylene glycol.

[0014] According to an embodiment of the present disclosure, the atomization liquid further includes at least one of a sweetening agent, a cooling agent, and an organic acid.

[0015] The second aspect of the present disclosure provides an atomizer, including a liquid storage chamber, an atomization component, and the atomization liquid according to any one of the above embodiments, wherein the liquid storage chamber is used to accommodate the atomization liquid, and the atomization component is fluidly connected to the liquid storage chamber and is used to form an aerosol from the atomization liquid.

[0016] The third aspect of the present disclosure provides an electronic atomization device, including the above atomizer and a battery component, and the battery component is used to supply power to the atomizer.

[0017] The atomizing liquid of the present disclosure combines a nicotine substitute of 0.1% to 5% by weight and a flavoring agent of 0.25% to 30% by weight, significantly reducing the irritation of the nicotine substitute in the atomizing liquid, making the taste of the atomizing liquid close to that of traditional tobacco and improving the satisfaction. Detailed implementation manners

[0018] The technical solutions in the embodiments of the present disclosure will be clearly and completely described below in conjunction with the embodiments of the present disclosure. Obviously, the described embodiments are only a part of the embodiments of the present disclosure, rather than all the embodiments. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present disclosure without creative efforts shall fall within the scope of protection of this application.

[0019] The percentage content or % in the present disclosure is, unless otherwise specified, the weight percentage content.

[0020] The satisfaction brought by using an electronic atomizing device and an atomizing liquid mainly includes two aspects: physiological and psychological. Currently, the physiological satisfaction is mainly achieved through the action of nicotine in the atomizing liquid on dopaminergic neurons to produce a reward effect. When a consumer inhales nicotine, it promotes the secretion of dopamine, making the consumer feel pleasure and satisfaction, which will drive the consumer to repeatedly inhale nicotine and thus become addicted. The way nicotine acts on dopaminergic neurons is mainly by binding to nicotinic acetylcholine receptors on the synaptic terminals of dopaminergic neurons or on neuronal cells, promoting the release of dopamine in brain regions related to addiction. When the dopamine concentration in the nucleus accumbens increases, people will experience reward, pleasure or satisfaction. The psychological need is mainly manifested as when a consumer smells, sees a tobacco product or is exposed to tobacco-related stimuli, it will awaken the tobacco-related memories in the brain region, thus causing excitement and secreting dopamine, and at this time the psychological need of the consumer is satisfied. Therefore, sensory stimuli in terms of taste, smell and trigeminal nerve will all strengthen the stimulating effect of nicotine on dopaminergic neurons. However, nicotine is highly addictive and is harmful to the human body, and after reducing the concentration, the desired effects of consumers cannot be satisfied.

[0021] Studies have shown that the lipophilicity of the 6-position substituent of nicotine can affect its affinity for nicotinic acetylcholine receptors, and the steric hindrance of this substituent can also regulate the strength of the affinity. The greater the steric hindrance, the weaker the affinity. For example, the 6-position substituent of 6-methyl nicotine has strong lipophilicity and the smallest steric hindrance, and has strong affinity. 6-Methyl nicotine has strong binding ability to nicotinic receptors on mouse meninges proteins, torpedo membrane proteins, and the cell membranes of Sf9 cells infected with baculovirus. The effect is about three times that of nicotine (Dukat, Malgorzata, et al. "Synthesis, receptor binding and QSAR studies on 6-substituted nicotine derivatives as cholinergic ligands." European Journal of Medicinal Chemistry 34.1 (1999): 31-40.; David, et al. "Structure-activity relationships for nicotine analogs comparing competition for [3H]nicotine binding and psychotropic potency." Drug Development Research 45.1 (1998): 10-16.). On the one hand, such nicotine substitutes have stronger binding ability to nicotinic acetylcholine receptors and can produce greater physiological satisfaction; on the other hand, their oral toxicity is lower than that of nicotine, and the addition amount required to achieve the same satisfaction as nicotine is lower, which can reduce the toxicity and intake of nicotine derivatives. However, these nicotine substitutes are highly irritating to the oral and throat areas, have a large difference in taste from traditional tobacco, and have disharmonious aromas. The poor sensory experience results in the inability to achieve the psychological satisfaction effect similar to that brought by traditional tobacco.

[0022] In view of the above problems, a first aspect of the present disclosure provides an atomization liquid. The atomization liquid includes 65 wt% - 99.65 wt% solvent, 0.1 wt% - 5 wt% nicotine substitute, and 0.25 wt% - 30 wt% flavoring agent, wherein the nicotine substitute is at least one selected from 6-alkyl nicotine and salts of 6-alkyl nicotine, and the alkyl group is an alkyl group having 1 - 4 carbon atoms.

[0023] The present disclosure utilizes 6-alkyl nicotine (or its salts), in combination with a certain amount of flavoring agents that exhibit the characteristic aroma of tobacco, to significantly reduce the irritation of the nicotine substitute in the atomization liquid while avoiding nicotine intake, making the taste similar to that of traditional tobacco and significantly enhancing the psychological satisfaction. Additionally, the improvement in physiological satisfaction further amplifies the effect of the flavoring agents. As shown in the following examples, when the total amount of the flavoring agent is above 0.25%, it can coordinate with 6-alkyl nicotine to reduce the irritation caused by 6-alkyl nicotine substances to a level where consumers do not feel discomfort, and can make the taste smoother, with the softness of the smoke reaching above 6.0 points and the reduction degree reaching above 6.5 points, thereby providing a stronger sense of satisfaction and a more pleasant sensory experience, making the atomization liquid close to the smoking experience of traditional cigarettes.

[0024] The atomization liquid of the present disclosure is described in detail below.

[0025] Nicotine substitute

[0026] Compared with other nicotine substitutes, the nicotine substitute of the present disclosure is 6-alkyl nicotine (including its salts) with an alkyl group having 1-4 carbon atoms, which not only has a strong ability to bind to nicotinic acetylcholine receptors but also has relatively low oral toxicity. Preferably, the 6-alkyl nicotine is 6-methyl nicotine and / or 6-ethyl nicotine, which bring a stronger sense of physiological satisfaction, have a more mature production process, and are more cost-effective.

[0027] In some embodiments, the 6-alkyl nicotine may exist in the form of its salts, and the salts are at least one selected from benzoate, malate, tartrate, citrate, acetylpropionate, and lactate. In the 6-alkyl nicotine in the form of salts, since the acid neutralizes the alkalinity of 6-alkyl nicotine, its irritation to the oral cavity, nasal cavity, and throat is smaller than that of 6-alkyl nicotine, giving consumers a smoother taste and being more conducive to consumers inhaling the aerosol deeper, thereby significantly improving the nicotine transmission efficiency and human absorption rate and more easily meeting the consumers' demand for satisfaction.

[0028] The atomization liquid of the present disclosure includes 0.5% to 1.5% by weight of nicotine substitute. Preferably, the addition amount of the nicotine substitute in the atomization liquid is 0.5% - 1.0%. Exemplarily, the nicotine addition amounts are 0.5%, 0.6%, 0.7%, 0.8%, 0.9%, 1%, 1.1%, 1.2%, 1.3%, 1.4%, 1.5%, etc. Since many countries and regions such as China, the European Union, and Canada restrict the nicotine content in nicotine liquid preparations to be lower than 2%, using the nicotine substitute of the present disclosure can generate sufficient physiological satisfaction at a low nicotine addition amount while reducing the intake of nicotine derivatives and their associated toxicity.

[0029] Flavoring agent

[0030] Flavoring agents in tobacco are mainly used to improve the taste, smell and color of tobacco, so as to increase consumers' acceptance of tobacco. The atomizing liquid of the present disclosure includes 0.25% to 30% by weight of flavoring agent, which can reduce the irritation of the nicotine substitute in the atomizing liquid and make the taste close to that of traditional tobacco.

[0031] In some embodiments, the flavoring agent includes furfuryl acetate, 6-isopropylquinoline and 2-methyl-3-ethylmaleimide. Furfuryl acetate naturally exists in beer, cocoa, roasted peanuts, etc., and has the smell of fruits, nuts and caramel, which can enhance the soft permeability of the smoke and increase the fruity and sweet taste. 6-Isopropylquinoline has a characteristic floral fragrance, and the aroma is strong, stable and powerful. 2-Methyl-3-ethylmaleimide has an elegant and slightly sweet flue-cured tobacco leaf aroma, which can enhance the richness and fullness of the smoke aroma, and at the same time increase the sweet taste. The combination of these three flavoring agents can effectively reduce the irritation of the nicotine substitute and obtain a taste close to that of tobacco, thereby enhancing the satisfaction.

[0032] In some embodiments, based on the weight of the atomizing liquid, the flavoring agent includes 0.1% to 3% by weight of furfuryl acetate, 0.05% to 2% by weight of 6-isopropylquinoline and 0.1% to 2% by weight of 2-methyl-3-ethylmaleimide. More preferably, the flavoring agent includes 1.0% to 1.5% by weight of furfuryl acetate, 0.5% to 1.5% by weight of 6-isopropylquinoline and 0.5% to 1.5% by weight of 2-methyl-3-ethylmaleimide. Exemplarily, the addition amount of furfuryl acetate is 0.1%, 0.5%, 0.8%, 1%, 1.1%, 1.2%, 1.3%, 1.4%, 1.5%, 2%, 2.5%, 3%, etc.; the addition amount of 6-isopropylquinoline is 0.05%, 0.1%, 0.3%, 0.5%, 0.6%, 0.7%, 0.8%, 0.9%, 1%, 1.1%, 1.2%, 1.3%, 1.4%, 1.5%, 1.7%, 2%, etc.; the addition amount of 2-methyl-3-ethylmaleimide is 0.1%, 0.3%, 0.5%, 0.6%, 0.7%, 0.8%, 0.9%, 1%, 1.1%, 1.2%, 1.3%, 1.4%, 1.5%, 1.7%, 2%, etc. Combining the three flavoring agents within the above addition amount range can significantly reduce the irritation of the nicotine substitute and obtain a balanced special aroma and taste.

[0033] In some embodiments, the flavoring agent further comprises at least one of 2-isobutyl-1,3-thiazole, N-(3-methylbutyl)pyrrolidine, N-(3-methylbutyl)acetamide, 2-piperidone, pyrrolidin-2-one, diethyl maleimide, 2-ethylidene-3-methylmaleimide, 2-ethyl-3-methylsuccinimide, N-methylsuccinimide, 2-isopropenylisophorone, 2,3-dimethyl-4-hydroxy-6-oxooctanoate, and 5-isopropyl-2-methylpyrazine. Using the above flavoring agent can further enrich the taste and odor experience. Each flavor has unique characteristics, and compounding multiple flavors can create a more diverse and more authentic tobacco-like mixed taste, enhancing the overall layering of the e-liquid. The present disclosure has no particular limitation on the addition amount of the above flavoring agent, as long as it does not produce irritating or unpleasant flavors.

[0034] Solvent

[0035] The solvent is used in the e-liquid to dissolve various components and generate an aerosol during atomization, giving consumers the feeling of puffing. The solvent is at least one selected from water, ethanol, ethylene glycol, propanol, propylene glycol, glycerol, butanol, butylene glycol, butanetriol, benzyl alcohol, triethyl citrate, triacetin, and caprylic / capric glycerides. The present disclosure has no particular limitation on the addition amount and ratio of each component in the solvent, and the addition amount and ratio in any conventional solvent for nicotine-containing e-liquids can be used for the e-liquid of the present disclosure.

[0036] In some embodiments, the solvent comprises glycerol (VG) and propylene glycol (PG). Glycerol is not only a solvent for the flavoring agent but also can generate a large amount of smoke after heating to meet the user's demand for the amount of smoke. Propylene glycol is a common pharmaceutical and food additive with a lower polarity than glycerol and good miscibility with various flavor components. PG and VG can be used in a certain proportion, for example, the mass ratio of PG to VG can be (10 - 50):(50 - 10).

[0037] Other additives

[0038] In some embodiments, the e-liquid further comprises at least one of a sweetening agent, a cooling agent, and an organic acid. The cooling agent and the sweetening agent can further provide tastes with different flavors. The organic acid can further reduce the irritation sensation generated in the throat and also improve the satisfaction to a certain extent.

[0039] The present disclosure places no particular restrictions on the types of sweeteners, cooling agents, and organic acids, and those commonly used can all be used in the atomization liquid. Examples include, but are not limited to, WS-3, WS-5, WS-12, WS-14, WS-23, WS-25, WS-27, menthol, menthol ether, and menthol esters as the cooling agents. Examples include, but are not limited to, acetic acid, butyric acid, 2-methylbutyric acid, lactic acid, levulinic acid, malic acid, tartaric acid, benzoic acid, and citric acid as the organic acids. Examples include, but are not limited to, neotame, advantame, sucralose, acesulfame potassium, glucosyl steviol glycoside, aspartame, hesperidin dihydrochalcone, neohesperidin dihydrochalcone, and naringin dihydrochalcone as the sweeteners. The present disclosure places no particular restrictions on the addition amounts of the sweeteners, cooling agents, and organic acids.

[0040] Preparation method

[0041] The present disclosure places no particular restrictions on the preparation method of the atomization liquid, and generally may include the step of uniformly mixing the components. According to some embodiments, the components can be heated and mixed evenly, for example, heated at about 30°C - 50°C for 10 - 20 minutes.

[0042] In a second aspect of the present disclosure, there is provided an atomizer, including a liquid storage chamber, an atomization component, and the atomization liquid according to any one of the above embodiments. Among them, the liquid storage chamber is used to accommodate the atomization liquid, and the atomization component is fluidly connected to the liquid storage chamber and is used to form an aerosol from the atomization liquid.

[0043] The atomization liquid of the present disclosure is applicable to various types of atomization components, such as resistance heating atomization components, flat sheet ultrasonic atomization components, vibrating mesh atomization components, electrostatic atomization components, infrared atomization components, and microwave atomization components, etc., but not limited thereto.

[0044] In a third aspect of the present disclosure, there is provided an electronic atomization device, including the atomizer according to any one of the above embodiments and a battery assembly, and the battery assembly is used to supply power to the atomizer.

[0045] The following further illustrates the present disclosure with specific examples. All the raw materials involved are obtained through commercial purchase.

[0046] Examples

[0047] Examples 1 - 10 and Comparative Examples 1 - 2

[0048] According to the formulations shown in Table 1, atomization liquid samples of Examples 1 - 10 and Comparative Examples 1 - 2 were prepared. Among them, for each raw material component by mass percentage, the nicotine substitute was 6-methyl nicotine, and the balance was the solvent. The solvent used was a mixture of propylene glycol and glycerol with a weight ratio of 60:40. The components were mixed evenly to obtain the samples.

[0049] Table 1 Weight percentages (%) of each component in the samples of Examples 1-10 and Comparative Examples 1-2

[0050]

[0051] The atomized liquids prepared in the above examples and comparative examples were filled into the same electronic atomization device, with 3 cartridges filled with each sample. Ten professional sensory evaluation personnel were selected to taste the atomized liquids prepared in the examples and comparative examples. Rinse the mouth before the test. Continuously suck two puffs of the sample each time, with each puff lasting for 2 s - 3 s; the interval between sucking each sample is not less than 5 minutes, and rest until there is no impact on the tasting of the next sample. Use a scale of 0 - 10 to score the smoothness, reduction degree, and satisfaction after sucking the sample, and the result is the average value. Among them, the smoothness is the degree of uncomfortable irritation caused by the smoke to the mouth, throat, and nasal cavity; the reduction degree is the similarity in taste between sucking the atomized liquid and sucking a cigarette; the satisfaction is the comprehensive sensory experience of the addiction relief feeling and the pleasant feeling generated by sucking. The specific evaluation indicators are shown in Table 2. The lower the irritation, the higher the corresponding smoothness score; the higher the similarity in taste to sucking a cigarette, the higher the reduction degree score; the stronger the addiction relief feeling and the pleasant feeling, the higher the satisfaction score.

[0052] Table 2 Scoring criteria for satisfaction, irritation, and reduction degree

[0053] Score Softness Reduction degree Satisfaction 0-2 Very strong sense of stimulation Basically none Basically none 2-4 Stronger sense of stimulation Weaker Weaker 4-6 There is a sense of stimulation There is There is 6-8 Weaker sense of stimulation Stronger Stronger 8-10 Basically no stimulation Basically the same Very strong

[0054] For each evaluation item, record the average value of all sensory evaluation data, and round the value to one decimal place. The sensory evaluation results of the atomized liquids of Examples 1-10 and Comparative Examples 1-2 are shown in Table 3.

[0055] Table 3 Sensory evaluation results of the atomized liquids of Examples 1-10 and Comparative Examples 1-2

[0056] Softness Reduction degree Satisfaction Example 1 8.8 8.6 8.5 Example 2 7.5 7.8 7.7 Example 3 7.6 7.9 7.8 Example 4 6.5 6.5 6.6 Example 5 7.6 7.8 7.9 Example 6 7.9 7.5 7.7 Example 7 6.7 6.5 6.7 Example 8 7.8 7.7 7.9 Example 9 7.9 7.8 7.8 Example 10 6.4 6.8 6.7 Comparative example 1 6.0 5.2 5.6 Comparative example 2 2.5 4.5 6.1

[0057] In Examples 1-10, all contain more than 0.25% by weight of flavoring agents, showing a smoking experience close to that of traditional cigarettes and a significantly improved satisfaction. In particular, using a combination of 3 flavoring agents can increase the satisfaction to 7.7 points or more.

[0058] Compared with Example 1, traditional nicotine is used in Comparative Example 1, and the satisfaction is significantly reduced.

[0059] Compared with Example 1, in Comparative Example 2, the contents of 3 flavoring agents, namely furfuryl acetate, 6-isopropylquinoline, and 2-methyl-3-ethylmaleimide, are too low, and the total amount of flavoring agents is less than 0.25%. After the atomized liquid generates smoke, it causes a strong uncomfortable feeling in the sensory organs, including the mouth, throat, and nasal cavity.

[0060] Compared with Example 1, Examples 4, 7, and 10 contain only two flavoring agents. Compared with other examples, the satisfaction is reduced. However, compared with Comparative Example 1, the satisfaction is still significantly improved; compared with Comparative Example 2, the irritation of the smoke is reduced, and the effect of restoring the smoking taste of cigarettes and enhancing the satisfaction can be achieved.

[0061] Examples 11 - 13

[0062] According to the formula shown in Table 6, prepare the atomized liquid samples of Examples 11 - 13, where more types of flavoring agents are used, and each component is calculated by mass percentage. Mix each component evenly to obtain the samples.

[0063] Table 6 Weight percentages (%) of each component in Examples 11 - 13

[0064]

[0065]

[0066] Using the above method, conduct a sensory evaluation on the atomized liquid samples of Examples 11 - 13, and the results are shown in Table 7.

[0067] Table 7 Sensory evaluation results of the atomized liquid of Examples 11 - 13

[0068] Softness Reduction degree Satisfaction Example 11 8.9 8.5 8.7 Example 12 9.0 8.7 8.8 Example 13 9.2 8.4 9.0

[0069] It can be seen from the above sensory evaluation results that by using richer flavoring agents, or further using sweeteners, cooling agents, and organic acids, Examples 11 - 13 show a smoking experience closer to that of traditional cigarettes and a further improved satisfaction.

[0070] The above are only some specific embodiments of the present disclosure, intended to illustrate the present disclosure, and are not used to limit the scope of protection required by this application. All modifications, substitutions, or direct / indirect applications made under the inventive concept of the present disclosure in other related technical fields are included within the scope of protection required by this application.

Claims

1. An atomization liquid, comprising: 65% to 99.65% by weight of a solvent, 0.1% to 5% by weight of a nicotine substitute, and 0.25% to 30% by weight of a flavorant, wherein the nicotine substitute is at least one selected from 6-alkyl nicotine and salts of 6-alkyl nicotine, and the alkyl group is an alkyl group having 1 to 4 carbon atoms.

2. The atomization liquid according to claim 1, wherein, The flavorant includes furfuryl acetate, 6-isopropylquinoline, and 2-methyl-3-ethylmaleimide.

3. The atomization liquid according to claim 2, wherein, Based on the weight of the atomizing liquid, the flavorant includes 0.1% to 3% by weight of furfuryl acetate, 0.05% to 2% by weight of 6-isopropylquinoline, and 0.1% to 2% by weight of 2-methyl-3-ethylmaleimide; preferably, the flavorant includes 1.0% to 1.5% by weight of furfuryl acetate, 0.5% to 1.5% by weight of 6-isopropylquinoline, and 0.5% to 1.5% by weight of 2-methyl-3-ethylmaleimide.

4. The atomization liquid according to claim 2, wherein, The flavorant further includes at least one of 2-isobutyl-1,3-thiazole, N-(3-methylbutyl)pyrrolidine, N-(3-methylbutyl)acetamide, 2-piperidone, pyrrolidin-2-one, diethylmaleimide, 2-ethylidene-3-methylmaleimide, 2-ethyl-3-methylsuccinimide, N-methylsuccinimide, 2-isopropenylisophorone, 2,3-dimethyl-4-hydroxy-6-oxooctanoate, and 5-isopropyl-2-methylpyrazine.

5. The atomization liquid according to claim 1, wherein, The 6-alkyl nicotine is 6-methyl nicotine and / or 6-ethyl nicotine, and the salt is at least one selected from benzoate, malate, tartrate, citrate, acetylpropionate, and lactate.

6. The atomization liquid according to any one of claims 1-5, wherein, Based on the weight of the atomizing liquid, the atomizing liquid includes 0.5% to 1.5% by weight of the nicotine substitute; preferably, the atomizing liquid includes 0.5% to 1.0% by weight of the nicotine substitute.

7. The atomization liquid according to claim 1, wherein, The solvent is at least one selected from water, ethanol, ethylene glycol, propanol, propylene glycol, glycerol, butanol, butylene glycol, butanetriol, benzyl alcohol, triethyl citrate, glyceryl triacetate, and caprylic / capric triglyceride; preferably, the solvent includes glycerol and propylene glycol.

8. The atomization liquid according to claim 1, further comprising at least one of a sweetening agent, a cooling agent, and an organic acid.

9. An atomizer, comprising a liquid storage chamber, an atomization assembly, and the atomization liquid according to any one of claims 1-8, wherein, The liquid storage chamber is used to hold the atomizing liquid, and the atomizing component is fluidly connected to the liquid storage chamber and is used to form an aerosol of the atomizing liquid.

10. An electronic atomization device, comprising the atomizer according to claim 9 and a battery assembly, the battery assembly being configured to supply power to the atomizer.

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