Thermal therapy system and use method thereof

Abstract

The invention discloses a thermal therapy system and a use method thereof. The thermal therapy system comprises a thermal therapy water storage device, a heating device, a cleaning device, a chemotherapy device and a hydrops storage device. The hydrothorax and ascites with tumor cells in the chest of the human body are pumped into an effusion storage device through a third driving pump; after effusion extraction is finished, chemotherapy liquid in a chemotherapy liquid container can be conveyed into a heating cavity of a heating device through an infusion apparatus to be heated, and then the heated chemotherapy liquid is conveyed into the chest of the human body through a first driving pump; after the chemotherapy liquid is conveyed, the cleaning liquid in the cleaning liquid container is conveyed into the heating cavity of the heating device through the second driving pump to be heated, and then the heated cleaning liquid is conveyed into the chest of the human body through the first driving pump to be washed clean; through the arrangement, a large number of tumor cells can be prevented from always existing in thermal therapy circulation when thermal therapy is carried out on a patient with widely planted pleuroperitoneal cavity tumor cells, and the thermal therapy effect can be effectively improved.

Description

Technical Field

[0001] The present invention relates to the field of medical technology, and particularly to a hyperthermia system and a method for using the same. Background Art

[0002] Tumor pleural effusion and ascites are common complications in patients with advanced tumors, which seriously affect the quality of life and prognosis of patients. At present, hyperthermia, as a means of treating tumor pleural effusion and ascites, shows unique advantages. Especially for patients with advanced stage who have extensive implantation in the chest and abdomen, its curative effect is significant and the side effects are significantly smaller compared with radiotherapy and chemotherapy, making it highly valuable for promotion.

[0003] However, the existing traditional hyperthermia methods have certain limitations. The traditional hyperthermia method is to drain the pleural effusion and ascites into a water storage tank first, heat it, and then reinfuse it into the chest and abdomen. However, for patients with extensive implantation of tumor cells in the chest and abdomen, this method will cause a large number of tumor cells to continuously exist in the circulatory system. This not only poses a risk of promoting the further spread and metastasis of tumor cells, but also affects the hyperthermia effect and increases the treatment risk. Therefore, the traditional hyperthermia method is difficult to meet the clinical treatment needs in the above situations. Summary of the Invention

[0004] Therefore, the present invention aims to solve the problem that the existing hyperthermia method will cause a large number of tumor cells to continuously exist in the circulatory system and affect the subsequent treatment effect when dealing with the situation where tumor cells have been extensively implanted in the chest and abdomen, and thus provides a hyperthermia system and a method for using the same.

[0005] To solve the above technical problems, the technical solution of the present invention is as follows:

[0006] A hyperthermia system, comprising:

[0007] A hyperthermia water storage device, including a hollow cavity adapted to store hyperthermia water, a circulation inlet communicated with the top of the hollow cavity, and a circulation outlet communicated with the bottom of the hollow cavity;

[0008] A heating device, installed at the bottom of the hyperthermia water storage device, including a heating cavity communicated with the hollow cavity and a first driving pump disposed between the circulation outlet and the heating cavity;

[0009] A cleaning device, including a cleaning liquid container communicated with the circulation inlet and adapted to accommodate cleaning liquid, and a second driving pump disposed between the cleaning liquid container and the circulation inlet;

[0010] A chemotherapy device, including a chemotherapy liquid container communicated with the circulation inlet and adapted to accommodate chemotherapy liquid, and an infusion device disposed between the chemotherapy liquid container and the circulation inlet;

[0011] The effusion storage device includes an effusion storage container adapted to hold effusion, a pre - filling tube provided on the effusion storage container, and a third driving pump provided on the pre - filling tube.

[0012] Further, the heating device includes a heating cavity communicated with the hollow cavity through a circulation tube and a heating element provided in the heating cavity. Liquid inlets for introducing liquid and liquid outlets for outputting liquid are respectively provided on both sides of the heating cavity, and the first driving pump is provided on the circulation tube.

[0013] Further, the heating device further includes a power supply and a temperature controller electrically connected to the heating element.

[0014] Further, an infusion tube is communicated with the cleaning liquid container, and a medicine delivery tube is communicated with the chemotherapy liquid container. The infusion tube and the medicine delivery tube are connected in parallel through a three - way joint a. The three - way joint a is communicated with the circulation inlet through a liquid inlet tube, and the second driving pump is provided on the infusion tube.

[0015] Further, stop - flow clamps are provided on both the infusion tube and the medicine delivery tube. When the infusion tube is in an open state, the medicine delivery tube is in a closed state, and when the infusion tube is in a closed state, the medicine delivery tube is in an open state.

[0016] Further, one end of the pre - filling tube away from the effusion storage container is communicated with an input tube and a liquid inlet tube through a three - way joint b. One end of the liquid inlet tube away from the three - way joint b is communicated with the circulation inlet, and one end of the input tube away from the three - way joint b is adapted to be connected to a target position. The opening and closing states of the pre - filling tube and the liquid inlet tube are opposite.

[0017] A method for using the hyperthermia system according to any one of the above, including the following steps:

[0018] S1: Output the effusion at the target position into the effusion storage device;

[0019] S2: Deliver the chemotherapy medicine liquid into the hyperthermia water storage device;

[0020] S3: Deliver the chemotherapy medicine liquid in the hyperthermia water storage device in step S2 into the heating device for heating;

[0021] S4: Output the chemotherapy medicine liquid in the heating device in step S3 to the target position;

[0022] S5: Deliver sterile water into the hyperthermia water storage device;

[0023] S6: Deliver the sterile water in the hyperthermia water storage device in step S5 into the heating device for heating;

[0024] S7: Output the sterile water in the heating device described in step S6 to the target position to rinse the target position.

[0025] Further, in step S1, a 3-inch rolling pump is used for driving to output the accumulated fluid at the target position into the accumulated fluid storage container.

[0026] Further, in step S2, another 3-inch rolling pump is used for driving to deliver the chemotherapy drug solution to the hyperthermia water storage device.

[0027] Further, in steps S3 and S6, other 3-inch rolling pumps are used for driving to respectively deliver the chemotherapy drug solution and the sterile water that enter the hyperthermia water storage device into the heating device for heating.

[0028] The technical solution of the present invention has the following advantages:

[0029] 1. The hyperthermia system provided by the present invention can aspirate the accumulated fluid (such as the pleural effusion with tumor cells in the human thoracic cavity) at the target position (such as in the human thoracic cavity) into the accumulated fluid storage device through the third driving pump; after the aspiration of the accumulated fluid is completed, the chemotherapy drug solution in the chemotherapy drug solution container can be delivered to the heating cavity of the heating device for heating through the infusion device, and then the heated chemotherapy drug solution can be delivered into the human thoracic cavity through the first driving pump; after delivering the chemotherapy drug solution, the cleaning solution in the cleaning solution container can be delivered to the heating cavity of the heating device for heating through the second driving pump, and then the heated cleaning solution can be delivered into the human thoracic cavity for rinsing, so as to rinse the human thoracic cavity clean; with such a setting, it can be avoided that a large number of tumor cells always exist in the hyperthermia cycle when patients with extensive implantation of tumor cells in the chest and abdomen undergo hyperthermia, and it can be avoided that the tumor cells further spread and metastasize due to this, and the hyperthermia effect can be effectively improved.

[0030] 2. The hyperthermia system provided by the present invention, the heating device further includes a power supply and a temperature controller electrically connected to the heating element. With such a setting, the temperature of the heating element can be adjusted through temperature control, and then the temperature of the liquid heated by the heating device can be adjusted and controlled, so that the liquid entering the human chest and abdomen meets the preset temperature.

[0031] 3. The hyperthermia system provided by the present invention, stop valves are provided on both the infusion tube and the medicine delivery tube. When the infusion tube is in an open state, the medicine delivery tube is in a closed state, and when the infusion tube is in a closed state, the medicine delivery tube is in an open state. With such a setting, it can be avoided that the sterile water in the cleaning device and the chemotherapy drug solution in the chemotherapy device are mixed and delivered, which affects the efficacy of the chemotherapy drug solution. Description of the Drawings

[0032] To more clearly illustrate the specific implementation methods of the present invention or the technical solutions in the prior art, the following will briefly introduce the drawings required for the description of the specific implementation methods or the prior art. Obviously, the drawings in the following description are some implementation methods of the present invention. For those of ordinary skill in the art, without creative efforts, other drawings can also be obtained based on these drawings.

[0033] Figure 1 Structural schematic diagram of the hyperthermia system provided by the embodiment of the present invention;

[0034] Explanation of reference numerals: 1. Hyperthermia water storage device; 2. Circulation inlet; 3. Circulation outlet; 4. Heating device; 5. First driving pump; 6. Cleaning liquid container; 7. Second driving pump; 8. Chemotherapy liquid container; 9. Infuser; 10. Effusion storage container; 11. Priming tube; 12. Third driving pump; 13. Circulation tube; 14. Heating element; 15. Liquid inlet; 16. Liquid outlet; 17. Power supply; 18. Temperature controller; 19. Infusion tube; 20. Medicine delivery tube; 21. Three-way joint a; 22. Feed pipe; 23. Stop clamp; 24. Three-way joint b; 25. Input pipe; 26. Inlet pipe. Specific implementation methods

[0036] The following will clearly and completely describe the technical solutions of the present invention with reference to the drawings. Obviously, the described embodiments are some embodiments of the present invention, rather than all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts belong to the scope of protection of the present invention.

[0037] In the description of the present invention, it should be noted that the orientation or positional relationship indicated by the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc. is based on the orientation or positional relationship shown in the drawings. It is only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of the present invention. In addition, the terms "first", "second", "third" are only used for descriptive purposes and cannot be construed as indicating or implying relative importance.

[0038] In the description of the present invention, it should be noted that, unless otherwise clearly specified and defined, the terms "installation", "connection", and "coupling" should be understood in a broad sense. For example, it may be a fixed connection, a detachable connection, or an integral connection; it may be a mechanical connection or an electrical connection; it may be a direct connection or an indirect connection through an intermediate medium, and it may be the communication inside two components. For those of ordinary skill in the art, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0039] In addition, the technical features involved in different embodiments of the present invention described below can be combined with each other as long as they do not conflict with each other.

[0040] Such as Figure 1 shown, a hyperthermia system includes a hyperthermia water storage device 1, a heating device 4, a cleaning device, a chemotherapy device, and an effusion storage device. Specifically, the hyperthermia water storage device 1 includes a hollow cavity adapted to store hyperthermia water, a circulation inlet 2 communicating with the top of the hollow cavity, and a circulation outlet 3 communicating with the bottom of the hollow cavity; the heating device 4 is installed at the bottom of the hyperthermia water storage device 1 and includes a heating cavity communicating with the hollow cavity and a first driving pump 5 disposed between the circulation outlet 3 and the heating cavity; the cleaning device includes a cleaning liquid container 6 communicating with the circulation inlet 2 and adapted to accommodate the cleaning liquid, and a second driving pump 7 disposed between the cleaning liquid container 6 and the circulation inlet 2; the chemotherapy device includes a chemotherapy liquid container 8 communicating with the circulation inlet 2 and adapted to accommodate the chemotherapy liquid, and an infusion device 9 disposed between the chemotherapy liquid container 8 and the circulation inlet 2; the effusion storage device includes an effusion storage container 10 adapted to accommodate the effusion, a pre-filled tube 11 disposed on the effusion storage container 10, and a third driving pump 12 disposed on the pre-filled tube 11.

[0041] In this hyperthermia system, the effusion (such as the pleural effusion containing tumor cells in the human chest cavity) at the target position (such as in the human chest cavity) can be aspirated into the effusion storage device through the third driving pump 12; after the effusion extraction is completed, the chemotherapy liquid in the chemotherapy liquid container 8 can be transported to the heating cavity of the heating device 4 for heating through the infusion device 9, and then the heated chemotherapy liquid can be transported into the human chest cavity through the first driving pump 5; after the chemotherapy liquid is transported, the cleaning liquid in the cleaning liquid container 6 is transported to the heating cavity of the heating device 4 for heating through the second driving pump 7, and then the heated cleaning liquid is transported into the human chest cavity for flushing, so as to flush the human chest cavity clean; with such a setting, it can be avoided that a large number of tumor cells always exist in the hyperthermia circulation when patients with widespread implantation of tumor cells in the chest and abdomen undergo hyperthermia, and it can be avoided that the tumor cells further spread and metastasize due to this, and the hyperthermia effect can be effectively improved.

[0042] In this embodiment, the heating device 4 includes a heating cavity communicated with the hollow cavity through a circulation pipe 13 and a heating element 14 disposed in the heating cavity. Liquid inlet ports 15 for introducing liquid and liquid outlet ports 16 for outputting liquid are respectively disposed on both sides of the heating cavity. The first driving pump 5 is disposed on the circulation pipe 13. Specifically, the heating device 4 further includes a power supply 17 and a temperature controller 18 electrically connected to the heating element 14. With such a setting, the temperature of the heating element 14 can be adjusted through temperature control, and further the temperature of the liquid heated by the heating device 4 can be adjusted and controlled so that the liquid entering the human chest and abdominal cavity meets the preset temperature.

[0043] In this embodiment, an infusion pipe 19 is communicated with the cleaning liquid container 6, and a medicine delivery pipe 20 is communicated with the chemotherapy liquid container 8. The infusion pipe 19 and the medicine delivery pipe 20 are connected in parallel through a three-way joint a21. The three-way joint a21 is connected to the circulation inlet 2 through a liquid inlet pipe 22. The second driving pump 77 is disposed on the infusion pipe 19. Specifically, stop clips 23 are disposed on both the infusion pipe 19 and the medicine delivery pipe 20. When the infusion pipe 19 is in an open state, the medicine delivery pipe 20 is in a closed state. When the infusion pipe 19 is in a closed state, the medicine delivery pipe 20 is in an open state. With such a setting, it is possible to avoid mixing and delivering the sterile water in the cleaning device and the chemotherapy liquid medicine in the chemotherapy device, which affects the efficacy of the chemotherapy liquid medicine.

[0044] In this embodiment, one end of the pre-filled pipe 11 far from the storage container is communicated with an input pipe 25 and a liquid inlet pipe 26 through a three-way joint b24. One end of the liquid inlet pipe 26 far from the three-way joint b24 is communicated with the circulation inlet 2. One end of the input pipe 25 far from the three-way joint b24 is adapted to be connected to the target position. The opening and closing states of the pre-filled pipe 11 and the liquid inlet pipe 26 are opposite.

[0045] A method for using the above-mentioned hyperthermia system includes the following steps:

[0046] S1: Output the effusion at the target position into the effusion storage device;

[0047] S2: Deliver the chemotherapy liquid medicine into the hyperthermia water storage device 1;

[0048] S3: Deliver the chemotherapy liquid medicine in the hyperthermia water storage device 1 in step S2 into the heating device 4 for heating;

[0049] S4: Output the chemotherapy liquid medicine in the heating device 4 in step S3 to the target position;

[0050] S5: Deliver the sterile water into the hyperthermia water storage device 1;

[0051] S6: Deliver the sterile water in the hyperthermia water storage device 1 in step S5 into the heating device 4 for heating;

[0052] S7: Output the sterile water in the heating device 4 in step S6 to the target position to flush the target position.

[0053] In step S1, drive with a 3-inch third roller pump, and output the pleural effusion with tumor cells in the human chest cavity to the effusion storage container 10 through the input pipe 25 and the pre-filled pipe 11 in sequence.

[0054] In step S2, drive with a 3-inch second roller pump, and transport the chemotherapy liquid medicine in the chemotherapy liquid container 8 to the hyperthermia water storage device 1 through the medicine delivery pipe 20 and the liquid inlet pipe 22 in sequence.

[0055] In step S3, drive with a 3-inch first roller pump, and transport the chemotherapy liquid medicine in the hyperthermia water storage device 1 in step S2 to the heating cavity of the heating device 4 through the circulation pipe 13 for heating; specifically, the heating temperature can be controlled by the temperature controller 18.

[0056] In step S4, under the drive of the first roller pump, output the chemotherapy liquid medicine in the heating device 4 in step S3 to the target position through the liquid outlet pipe.

[0057] In step S5, transport the sterile water to the hyperthermia water storage device 1 through the infusion pipe 19 and the liquid inlet pipe 22 in sequence by the precision infusion pump 9.

[0058] In step S6, drive with a 3-inch first roller pump, and transport the sterile water in the hyperthermia water storage device 1 in step S5 to the heating cavity of the heating device 4 through the circulation pipe 13 for heating; specifically, the heating temperature can be controlled by the temperature controller 18.

[0059] In step S7, under the drive of the first roller pump, output the sterile water in the heating device 4 in step S6 to the target position to flush the target position.

[0060] In summary, for this hyperthermia system and its usage method, the liquid accumulation (such as the pleural effusion containing tumor cells in the human thoracic cavity) at the target position (such as inside the human thoracic cavity) can be aspirated into the liquid accumulation storage device through the third driving pump 12; after the liquid accumulation extraction is completed, the chemotherapy liquid in the chemotherapy liquid container 8 can be transported to the heating cavity of the heating device 4 through the infusion device 9 for heating, and then the heated chemotherapy liquid can be transported into the human thoracic cavity through the first driving pump 5; after transporting the chemotherapy liquid, the cleaning liquid in the cleaning liquid container 6 can be transported to the heating cavity of the heating device 4 through the second driving pump 7 for heating, and then the heated cleaning liquid can be transported into the human thoracic cavity through the first driving pump 5 for flushing, thereby flushing the human thoracic cavity clean; with such a setting, it is possible to avoid a large number of tumor cells always existing in the hyperthermia cycle during hyperthermia for patients with extensive implantation of tumor cells in the chest and abdomen, avoid further spread and metastasis of tumor cells caused thereby, and effectively improve the hyperthermia effect.

[0061] Obviously, the above embodiments are merely examples given for clear illustration and are not limitations on the implementation methods. For those of ordinary skill in the art, other different forms of changes or modifications can be made based on the above description. It is not necessary and impossible to enumerate all the implementation methods here. And the obvious changes or modifications derived therefrom are still within the protection scope of this invention.

Claims

1. A thermal therapy system, characterized in that: include: A thermotherapy water storage device (1) comprises a hollow cavity suitable for storing thermotherapy water, a circulation inlet (2) connected to the top of the hollow cavity, and a circulation outlet (3) connected to the bottom of the hollow cavity; A heating device (4) is installed at the bottom of the thermotherapy water storage device (1), comprising a heating cavity connected to the hollow cavity and a first driving pump (5) arranged between the circulation outlet (3) and the heating cavity; The cleaning device comprises a cleaning liquid container (6) which is in communication with the circulation inlet (2) and is suitable for containing cleaning liquid, and a second driving pump (7) which is arranged between the cleaning liquid container (6) and the circulation inlet (2); A chemotherapy device, comprising a chemotherapy liquid container (8) connected to the circulation inlet (2) and suitable for containing chemotherapy liquid, and an infusion device (9) arranged between the chemotherapy liquid container (8) and the circulation inlet (2); The accumulated liquid storage device comprises an accumulated liquid storage container (10) suitable for accommodating accumulated liquid, a pre-filling pipe (11) arranged on the accumulated liquid storage container (10), and a third driving pump (12) arranged on the pre-filling pipe (11).

2. The thermal therapy system according to claim 1, characterized in that: The heating device (4) comprises a heating cavity connected to the hollow cavity through a circulation pipe (13) and a heating element (14) arranged in the heating cavity, and a liquid inlet (15) for introducing liquid and a liquid outlet (16) for outputting liquid are respectively arranged on both sides of the heating cavity, and the first driving pump (5) is arranged on the circulation pipe (13).

3. The thermal therapy system according to claim 2, characterized in that: The heating device (4) also includes a power supply (17) and a temperature controller (18) electrically connected to the heating element (14).

4. The thermal therapy system according to claim 1, characterized in that: The cleaning liquid container (6) is connected to an infusion tube (19), and the chemotherapy liquid container (8) is connected to a drug infusion tube (20). The infusion tube (19) and the drug infusion tube (20) are connected in parallel via a three-way connector a (21). The three-way connector a (21) is connected to the circulation inlet (2) via a liquid inlet tube (22). The second driving pump (7) is arranged on the infusion tube (19).

5. The thermal therapy system according to claim 4, characterized in that: The infusion tube (19) and the drug delivery tube (20) are both provided with a liquid-stopping clamp (23); when the infusion tube (19) is in an open state, the drug delivery tube (20) is in a closed state; and when the infusion tube (19) is in a closed state, the drug delivery tube (20) is in an open state.

6. The thermal therapy system according to claim 1, characterized in that: The end of the pre-filling tube (11) away from the accumulated liquid storage container (10) is connected to an input tube (25) and a liquid inlet tube (26) via a three-way joint b (24); the end of the liquid inlet tube (26) away from the three-way joint b (24) is connected to the circulation inlet (2); the end of the input tube (25) away from the three-way joint b (24) is suitable for connecting to a target position; the opening and closing states of the pre-filling tube (11) and the liquid inlet tube (26) are opposite.

7. A method for using the thermal therapy system according to any one of claims 1 to 6, characterized in that: The following steps are involved: S1: Outputting the accumulated fluid at the target position to the accumulated fluid storage device; S2: delivering the chemotherapy liquid to the hyperthermia water storage device (1); S3: transporting the chemotherapy liquid in the thermotherapy water storage device (1) in step S2 to the heating device (4) for heating; S4: Outputting the chemotherapy liquid in the heating device (4) in step S3 to the target location; S5: transporting sterile water to the hyperthermia water storage device (1); S6: transporting the sterile water in the thermotherapy water storage device (1) in step S5 to the heating device (4) for heating; S7: Outputting the sterile water in the heating device (4) in step S6 to the target location to flush the target location.

8. The method for using the thermal therapy system according to claim 7, characterized in that: In the step S1 , a 3-inch rolling pump is used to drive and output the accumulated liquid at the target position into the accumulated liquid storage container 10 .

9. The method for using the thermal therapy system according to claim 7, characterized in that: In step S2, another 3-inch scroll pump is used to drive and deliver the chemotherapy solution to the hyperthermia water storage device (1).

10. The method for using the thermal therapy system according to claim 7, characterized in that: In the steps S3 and S6, another 3-inch rolling pump is used to drive the chemotherapy solution and sterile water respectively entering the thermal therapy water storage device (1) to be transported to the heating device (4) for heating.

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