Digital PCR chip imaging scanner

Abstract

A digital PCR chip imaging scanner disclosed by the present invention comprises a housing module, an XYZ motion platform module sleeved in the housing module, an installation reference platform and an optical module, and the XYZ motion platform module and the optical module are respectively arranged at the top and the bottom of the installation reference platform. The Y-axis base plate in the installation reference platform is located above the X-axis base plate and is in transmission connection with an objective table, a discharging groove aligned with the objective table is formed in the front end of the shell module, and a bin door assembly is arranged in the discharging groove in a sleeved mode. According to the bin door assembly, in the process that a transmission mechanism corresponding to a Y-axis base plate drives a Y-axis base plate and an objective table to conduct bin discharging, the objective table abuts against and drives a bin door body, the bin door body synchronously turns over under hinged rotation of a curved plate relative to a shell module, and a tension spring deforms, expands and avoids; the space of the discharging groove is reserved, and the objective table can be moved out of the discharging groove to the outside of the shell module, so that the problem of mistaken collision is solved while the operation efficiency is improved.

Description

Technical Field

[0001] The present invention relates to the technical field of chip scanners, and in particular to a digital PCR chip imaging scanner. Background Art

[0002] Digital PCR chip imaging scanner, also known as digital PCR instrument, is an important tool of third-generation PCR technology. It is usually composed of an XYZ motion platform, an optical module, a PC module and a power supply. When in use, the digital PCR instrument can divide the sample into tens of thousands of nanoliter droplets through the microfluidic chip. Each droplet independently completes PCR amplification, and then photographs the digital PCR chip on the XYZ motion platform through the optical module. The light source module in the optical module emits light of a specific wavelength to excite the fluorescent probe or dye in the reaction system of the digital PCR chip. The light emitted by the fluorescent probe or dye is screened by lenses and filters, and detectors such as CMOS convert the optical signal into an electrical signal. After processing, it is transmitted to the data analysis system, that is, the PC module, to complete the purpose of automatic scanning and detection. Compared with traditional similar equipment, the digital PCR instrument can achieve absolute quantification of nucleic acid molecules without relying on standard curves.

[0003] However, during the actual operation, the applicant found that the currently used digital PCR chip imaging scanner still has some defects in its hardware structure. For example, the door on the surface of the digital PCR chip imaging scanner needs to be manually opened during the process of taking and placing the stage to detect raw materials. Although a corresponding automated power structure has been designed, it is necessary to wait until the door is fully opened before the stage can be adjusted to move out of the device through the XYZ motion platform. The long operation time also creates a safety hazard of misoperation causing the stage to collide with the door, which is not conducive to novice operation. Summary of the Invention

[0004] (1) Technical problems solved In view of the shortcomings of the existing technology, the present invention provides a digital PCR chip imaging scanner, which solves the problems raised in the above background technology.

[0005] (2) Technical solution To achieve the above objectives, the present invention provides the following technical solution: a digital PCR chip imaging scanner, comprising a housing module, an XYZ motion platform module, a mounting reference platform, and an optical module mounted within the housing module, wherein the XYZ motion platform module and the optical module are respectively disposed at the top and bottom of the mounting reference platform, and a Y-axis baseplate within the mounting reference platform is positioned above the X-axis baseplate and is transmission-connected to a stage; The front end of the housing module is provided with a discharge chute aligned with the loading platform, and a door assembly is installed in the discharge chute, and the door assembly includes a door body, a curved plate, and a tension spring. The two ends of the curved plate are respectively connected to the bottom of the front end of the door body and pass through the discharge chute and are hinged to the inner wall of the housing module through a pin shaft. The two ends of the tension spring are respectively fixed to one end of the curved plate and the inner wall of the housing module; The loading platform can reciprocate and press the transmission bin door body under the drive of the installation reference platform and move to the outside of the shell module after the bin door body flips over and gives way. In the process of resetting the loading platform by the installation reference platform, the bin door body is simultaneously acted upon by the elastic force of the tension spring and drives the curved plate to reset and close the discharge chute.

[0006] Preferably, a Hall sensor and a permanent magnet are installed on the inner wall of the front end of the housing module and the rear end structure of the top of the door body, respectively. Bearings are installed on both sides of the rear end of the top of the door body through bearing sleeves, and the bearings can be rollingly connected with the bottom of the loading platform when the loading platform presses the door body. The interior of the curved plate is provided with a receiving groove capable of receiving the tension spring set, the front inner wall of the discharge trough is provided with an annular groove, and the rear end surface of the door body is fixed with a boss capable of clamping and sealing the annular groove.

[0007] Preferably, a baffle is provided at the rear end of the loading platform, and the baffle is fitted and sealed on the discharge chute at the front end of the housing module after the loading platform is located outside the housing module.

[0008] Preferably, the loading platform includes a first bracket, a second bracket, a third bracket, and assembly screws. The first bracket, the second bracket, and the third bracket are stacked and assembled in sequence from top to bottom, and leveling screw holes are provided in the side structures on both sides of the second bracket. Leveling screws are installed in the side structures on both sides of the first bracket, and one end of the leveling screw can be threadedly connected to the leveling screw hole to adjust the horizontality of the first bracket on the top of the second bracket; A first clearance hole is provided in the side structures on both sides of the second bracket, a second clearance hole is provided in the side structures on both sides of the first bracket, and an assembly screw hole is provided in the side structures on both sides of the third bracket, and the first bracket, the second bracket, and the third bracket can be assembled and fixed in a detachable manner by sequentially fitting the assembly screws into the first clearance holes and the second clearance holes and then threadedly connected to the assembly screw holes; An upper magnet is sheathed in the side of the first bracket, and a lower magnet that can be magnetically connected to the upper magnet is sheathed in the side of the second bracket.

[0009] Preferably, the interior of the shell module is equipped with a PC power module, an embedded PC module, and a power module, and a heat dissipation device is provided in the bottom of the shell module, the heat dissipation device includes a cooling fan, and the rear end of the bottom of the shell module and the inner wall of the bottom are respectively provided with a plurality of ventilation holes, a through-shaped step groove, and a connecting notch. The connecting notch is communicated with the step groove space and is clamped with a magnetic dustproof net. The magnetic dustproof net can remove dust and filter the air entering the interior of the shell module, and the bottom of the shell module is covered with a power supply air duct communicated with the ventilation hole space.

[0010] Preferably, the magnetic dustproof net is composed of a magnetic stripe frame plate and a filter fixedly nested in the magnetic stripe frame plate, the bottom inner wall of the step groove is fixedly nested with an auxiliary magnetic strip that can be magnetically attracted to the magnetic stripe frame plate, and the surface of the magnetic stripe frame plate is fixed with a protrusion handle that can protrude to the outside of the connecting slot.

[0011] The shell structure at the bottom of the housing module is internally threadedly connected to a limiting screw, and the nut structure of the limiting screw itself can press and limit the side edges of the magnetic dustproof net and the auxiliary magnetic strip.

[0012] Preferably, self-locking holes are provided in the Y-axis substrate and the X-axis substrate inside the XYZ motion platform module, and the XYZ motion platform module can be adjusted to zero and align the two self-locking holes, and a self-locking component is provided between the XYZ motion platform module and the mounting reference platform; The self-locking component includes a connecting rod and a steering gear. The output end of the steering gear is connected to a disc, and a straight hole is provided on the middle surface of the disc. One end of the connecting rod is hingedly installed with the disc through a pin, and the other end of the connecting rod is hingedly installed with a guide cylinder clamped inside the installation reference platform through a pin. The guide cylinder is sequentially locked with two self-locking holes in an aligned state when the steering gear transmits the transmission through the disc and the connecting rod in sequence.

[0013] Preferably, a guide cylinder capable of being engaged with a limit rod is sheathed inside the installation reference platform, and a fixing seat is installed between the housing surface of the servo and the surface of the installation reference platform.

[0014] Preferably, a buffer flange is installed between the mounting reference platform and the bottom of the XYZ motion platform module, and the buffer flange is made of soft rubber material; An identification module is installed on the top of the installation reference platform, and the identification range of the identification module includes the QR code.

[0015] Preferably, the front end of the housing module is provided with an indicator light, a power on / off button, and an entry / exit button, and the indicator light can reflect the operating status of the housing module by displaying different colors.

[0016] Beneficial effects The present invention provides a digital PCR chip imaging scanner, which has the following beneficial effects: 1. The digital PCR chip imaging scanner is provided with a door assembly as a condition for opening the internal space of the shell module. Subsequently, when the transmission mechanism corresponding to the Y-axis substrate drives the Y-axis substrate and the stage to move out of the warehouse, the stage will press the transmission door body, and the pressed door body will be synchronously flipped under the hinged rotation of the curved plate relative to the shell module. The tension spring deforms and expands to make way, thereby making way for the discharge slot space at the front end of the shell module and enabling the stage to be moved out of the discharge slot to the outside of the shell module, providing sufficient operating space for the user to adjust and use the stage, thereby improving operating efficiency while eliminating the problem of accidental collision.

[0017] 2. The digital PCR chip imaging scanner is equipped with a door assembly, and the bearings further arranged inside the door assembly can reduce the friction loss in the process of the stage pressing the door body, and reduce the friction noise. The door body is fixed with a tension spring, and a storage groove is provided on the curved plate to avoid the position displacement of the tension spring. After the door body automatically closes, the permanent magnet and the Hall sensor cooperate to detect whether it is closed, so as to avoid starting the experiment with the door not closed, causing ambient light to irradiate the interior and affect the imaging effect, thereby further optimizing the use effect of the entire device.

[0018] 3. The digital PCR chip imaging scanner uses a detachable and replaceable magnetic dustproof net as a dustproof means. After being installed at the bottom of the shell module, it can fit tightly to prevent large foreign objects from entering the shell module. The magnetic dustproof net itself is tightly connected to the auxiliary magnetic strip and is also easy to pull out, replace and clean, so it can be used continuously, reducing the cost of use.

[0019] 4. The digital PCR chip imaging scanner is equipped with a self-locking component that can automatically limit the position in conjunction with the two self-locking holes set inside the XYZ motion platform module after the XYZ motion platform module is zeroed and adjusted, thereby self-locking the XYZ motion platform module to prevent the XYZ motion platform module from moving freely during transportation and causing damage to related structures. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] Figure 1 It is a front view schematic diagram of the structure of the present invention; Figure 2 It is a rear view schematic diagram of the structure of the present invention; Figure 3 It is a right side schematic diagram of the XYZ motion platform module of the present invention; Figure 4 It is a left side schematic diagram of the XYZ motion platform module of the present invention; Figure 5 Schematic top view of the XYZ motion platform module of the present invention; Figure 6 It is a front view schematic diagram of the annular groove structure of the present invention; Figure 7 It is a cross-sectional schematic diagram of the structural door assembly of the present invention; Figure 8 Schematic top view of the structure of the door body of the present invention; Figure 9 It is a rear view schematic diagram of the cabin door body of the present invention; Figure 10 It is a top view schematic diagram of the storage slot of the structure of the present invention; Figure 11 It is a right side schematic diagram of the structural curved plate of the present invention; Figure 12 Schematic top view of the structural stage of the present invention; Figure 13 It is a front view schematic diagram of the structural baffle of the present invention; Figure 14 Schematic cross-sectional view of the structural stage of the present invention; Figure 15 Schematic cross-sectional view of the upper magnet of the structure of the present invention; Figure 16 Schematic bottom view of the magnetic dust screen structure of the present invention; Figure 17 It is an enlarged schematic diagram of the magnetic dustproof net structure of the present invention; Figure 18 This is a schematic cross-sectional view of the power supply air duct of the present invention; Figure 19 It is a cross-sectional schematic diagram of the self-locking component of the structure of the present invention; Figure 20 It is a cross-sectional schematic diagram of the buffer flange structure of the present invention; Figure 21 It is a three-dimensional schematic diagram of the structural buffer flange of the present invention.

[0021] In the figure: 1. Housing module; 2. XYZ motion platform module; 3. Mounting reference platform; 4. Optical module; 5. Stage; 51. First bracket; 52. Second bracket; 53. Third bracket; 54. Leveling screw; 55. Assembly screw; 56. Upper magnet; 57. Lower magnet; 6. Door assembly; 61. Door body; 62. Curved plate; 63. Tension spring; 64. Bearing; 65. Hall sensor; 66. Permanent magnet; 67. Storage slot; 68. Boss. 7. Annular groove; 8. PC power module; 9. Embedded PC module; 10. Power module; 11. Baffle; 12. Self-locking component; 121. Connecting rod; 122. Limit rod; 123. Guide cylinder; 124. Disc; 125. Servo; 13. Buffer flange; 14. Magnetic dust screen; 15. Auxiliary magnetic strip; 16. Limit screw; 17. Ventilation hole; 18. Power duct; 19. Indicator light; 20. Power on / off button; 21. In / out button; 22. Identification module. DETAILED DESCRIPTION

[0022] Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making any creative work shall fall within the scope of protection of the present invention.

[0023] The present invention provides a technical solution: See also Figures 1-11 A digital PCR chip imaging scanner includes a housing module 1. The front end of the housing module 1 is provided with an indicator light 19, a power button 20, and an in-and-out button 21. The indicator light 19 can reflect the operating status of the housing module 1 by displaying different colors. An XYZ motion platform module 2, a mounting reference platform 3, and an optical module 4 are mounted inside the housing module 1. The XYZ motion platform module 2 and the optical module 4 are respectively arranged on the top and bottom of the mounting reference platform 3. The Y-axis baseboard inside the mounting reference platform 3 is located above the X-axis baseboard and is transmission-connected to the stage 5. The front end of the housing module 1 is provided with a discharge chute aligned with the loading platform 5, and a bin door assembly 6 is installed in the discharge chute, and the bin door assembly 6 includes a bin door body 61, a curved plate 62, and a tension spring 63. The two ends of the curved plate 62 are respectively connected to the bottom of the front end of the bin door body 61 and pass through the discharge chute and are hinged to the inner wall of the housing module 1 through a pin shaft. The two ends of the tension spring 63 are respectively fixed to one end of the curved plate 62 and the inner wall of the housing module 1. The loading platform 5 can reciprocate and press the transmission bin door body 61 under the drive of the installation reference platform 3 and move to the outside of the housing module 1 after the bin door body 61 is flipped over and gives way. In the process of resetting the loading platform 5 to the installation reference platform 3, the bin door body 61 is synchronously acted upon by the elastic force of the tension spring 63 and drives the curved plate 62 to reset and close the discharge chute, thereby preventing ambient light from irradiating the interior of the machine after the bin door body 61 is closed; A Hall sensor 65 and a permanent magnet 66 are installed on the inner wall of the front end of the housing module 1 and the rear end structure of the top of the door body 61, respectively. The Hall sensor 65 and the permanent magnet 66 are used to detect the closed state of the door body 61 to prevent the door body 61 from being opened when the experiment begins, causing ambient light to penetrate the interior and affect the imaging effect. Bearings 64 are installed on both sides of the rear end of the top of the door body 61 through bearing sleeves. The bearings 64 can be connected to the bottom of the stage 5 in a rolling manner when the stage 5 presses the door body 61, thereby reducing damage to parts caused by friction and reducing friction noise. The interior of the curved plate 62 is provided with a storage groove 67 that can accommodate the tension spring 63, thereby avoiding the position displacement of the tension spring. The front inner wall of the discharge trough is provided with an annular groove 7, and the rear end surface of the door body 61 is fixed with a boss 68 that can clamp and seal the annular groove 7, further improving the contact surface between the door body 61 and the discharge trough, and then further reducing the probability of ambient light irradiating the interior of the shell module 1. The rear end of the stage 5 is provided with a baffle 11, and the baffle 11 is fitted and sealed on the discharge trough at the front end of the shell module 1 after the stage 5 is in the external position of the shell module 1, thereby preventing dust in the air from drifting into the interior of the shell module 1 after the stage 5 is moved out of the outside of the shell module 1, thereby ensuring the imaging quality of the overall equipment for long-term use.

[0024] During use, for the preparation operation on the optical module 4, the transmission mechanism corresponding to the Y-axis substrate drives the Y-axis substrate and the stage 5 to press the door body 61. The door body 61 under pressure will be synchronously flipped under the hinged rotation of the curved plate 62 relative to the shell module 1, and the tension spring 63 will deform and expand to make way, and then make way for the discharge slot at the front end of the shell module 1. At the same time, the stage 5 will also be synchronously moved out of the discharge slot to the outside of the shell module 1, thereby providing sufficient operating space for the user. In addition, during the pressing contact between the loading platform 5 and the door body 61, the bearing 64 contacts the loading platform 5 first and reduces the friction loss and impact noise between the loading platform 5 and the door body 61 by rolling friction reduction. Subsequently, after the transmission mechanism corresponding to the Y-axis substrate drives the Y-axis substrate and the worktable 5 to reset to the inside of the shell module 1, the warehouse door body 61 will be synchronously reset and moved under the action of the reset elastic force of the tension spring 63, and after the warehouse door body 61 re-closes the discharge chute, the permanent magnet 66 and the Hall sensor 65 will perform real-time detection of the connection distance between the warehouse door body 61 and the shell module 1 to avoid the situation where the warehouse door body 61 is not closed or is not completely closed and the entire equipment is started.

[0025] See also Figure 12-15The loading platform 5 includes a first bracket 51, a second bracket 52, a third bracket 53, and an assembly screw 55. The first bracket 51, the second bracket 52, and the third bracket 53 are stacked and assembled from top to bottom, and leveling screw holes are provided in the side structures on both sides of the second bracket 52. Leveling screws 54 are installed in the side structures on both sides of the first bracket 51, and one end of the leveling screw 54 can be threadedly connected to the leveling screw hole and adjust the horizontality of the first bracket 51 at the top of the second bracket 52, thereby meeting the leveling work of the internal structure of the loading platform 5 without disassembling the shell module 1; The second bracket 52 has first clearance holes formed in its side structures on both sides, the first bracket 51 has second clearance holes formed in its side structures on both sides, and the third bracket 53 has assembly screw holes formed in its side structures on both sides. The first bracket 51, the second bracket 52, and the third bracket 53 can be assembled and fixed detachably by sequentially fitting the assembly screws 55 into the first clearance holes and the second clearance holes and then threadedly connected to the assembly screw holes. This allows the internal structure of the stage 5 to be repaired or replaced without disassembling the housing module 1. An upper magnet 56 is mounted on the side of the first bracket 51 , and a lower magnet 57 is mounted on the side of the second bracket 52 , which can be magnetically connected to the upper magnet 56 , further improving the convenience of assembling the first bracket 51 and the second bracket 52 .

[0026] During use, after the transmission mechanism corresponding to the Y-axis substrate transmits the Y-axis substrate and the stage 5 to press the door body 61 and move the first bracket 51 to the outside of the shell module 1, the first bracket 51 can be directly leveled. Specifically, the leveling screw 54 is turned to adjust the gap between it and the leveling screw hole. When replacing the first bracket 51 or the second bracket 52, it is only necessary to turn the assembly screw 55 and disassemble it to flexibly separate the first bracket 51 and the second bracket 52.

[0027] See also Figure 3-Figure 4 , Figure 16-18, the interior of the shell module 1 is equipped with a PC power module 8, an embedded PC module 9, and a power module 10, and a heat dissipation device is provided at the bottom of the shell module 1, and the heat dissipation device includes a cooling fan, and the rear end of the bottom of the shell module 1 and the inner wall of the bottom are respectively provided with a plurality of ventilation holes 17, a through-shaped step groove, and a connecting notch. The connecting notch is connected to the step groove space and is clamped with a magnetic dustproof net 14. The magnetic dustproof net 14 can remove dust and filter the air entering the shell module 1, and the bottom of the shell module 1 is covered with a power duct 18 that is connected to the ventilation hole 17 space; the magnetic dustproof net 14 consists of a magnetic stripe frame plate and a filter fixedly nested in the magnetic stripe frame plate, and the bottom inner wall of the step groove is fixedly nested with an auxiliary magnetic strip 15 that can be magnetically attracted to the magnetic stripe frame plate to improve the connection strength. The surface of the magnetic stripe frame plate is fixed with a protruding handle that can protrude to the outside of the connecting notch to facilitate subsequent removal operation; The shell structure at the bottom of the shell module 1 is internally threadedly connected to a limiting screw 16, and the nut structure of the limiting screw 16 itself can press and limit the side edges of the magnetic dustproof net 14 and the side edges of the auxiliary magnetic strip 15, thereby ensuring the installation and fixing effect of the magnetic dustproof net 14 at the bottom of the shell module 1.

[0028] When in use, the PC power module 8 and the power module 10 provide power for the operation of each module inside the machine, the embedded PC module 9 controls the operation of the machine, and finally processes and analyzes the data collected by the optical module 4 to output the test results desired by the user; The cooling fan is used to ventilate and dissipate heat to the components inside the housing module 1. At the same time, the outside air will be filtered and dust-removed through the magnetic dustproof net 14 before entering the interior of the housing module 1. The power supply air duct 18 is provided to prevent the existing fan in the power module 10 from affecting the air flow at the bottom of the housing module 1. After the magnetic dust screen 14 has been used for a period of time, the magnetic dust screen 14 can be pulled out from the interior of the housing module 1 by gripping the protruding handle, and can be put back into use after cleaning.

[0029] See also Figure 19, self-locking holes are provided in the Y-axis substrate and the X-axis substrate inside the XYZ motion platform module 2, and the XYZ motion platform module 2 can be adjusted to zero and align the two self-locking holes, and a self-locking component 12 is provided between the XYZ motion platform module 2 and the installation reference platform 3, and the self-locking component 12 includes a connecting rod 121 and a steering gear 125. The output end of the steering gear 125 is connected to a disc 124 in a transmission manner, and a straight hole is provided on the middle surface of the disc 124. One end of the connecting rod 121 is connected to the pin The shaft is hingedly installed with the disc 124, and the other end of the connecting rod 121 is hingedly installed with a guide cylinder 123 that is clamped inside the mounting reference platform 3 through a pin shaft. The guide cylinder 123 is sequentially driven by the servo 125 through the disc 124 and the connecting rod 121 to be clamped and limited with the two self-locking holes in the aligned state. The interior of the mounting reference platform 3 is equipped with a guide cylinder 123 that can be clamped with the limit rod 122, and a fixing seat is installed between the shell surface of the servo 125 and the surface of the mounting reference platform 3.

[0030] During use, during the transportation of the entire device, the zeroing function of the XYZ motion platform module 2 needs to be used to reset its own transmission structure in the X, Y, and Z directions. After completion, the servo 125 is started, and the output end of the servo 125 drives the disc 124 to rotate, and then the transmission limit rod 122 automatically moves up and engages with the two self-locking holes under the conversion of the connecting rod 121 to self-lock the XYZ motion platform module 2, thereby avoiding free movement of the XYZ motion platform module 2 during transportation and causing damage to the machine. The servo 125 can execute self-feedback angle, and there is no need to install detection mechanisms such as limit photoelectricity. A slotted hole is reserved in the middle of the disc 124. If there is any abnormality in the mechanism, it can be manually locked with a slotted screwdriver.

[0031] See also Figure 5 、 Figure 20-21 A buffer flange 13 is installed between the mounting reference platform 3 and the bottom of the XYZ motion platform module 2, and the buffer flange 13 is made of soft rubber material. An identification module 22 is installed on the top of the mounting reference platform 3, and the recognition range of the identification module 22 includes the QR code.

[0032] When in use, the buffer flange 13 is used in the connection gap between the XYZ motion platform module 2 and the mounting reference platform 3 to avoid the ineffectiveness of the shock-absorbing pad caused by the rigid connection, and at the same time play a role in sealing and dustproofing; The identification module 22 can identify the identification code of each digital PCR chip, including but not limited to the QR code, and the QR code chip recognition, the sample has a unique QR code. After the sample is placed, the internal QR code will identify and mark the sample. After analysis, the result is bound to the sample and can be traced and queried at any time.

[0033] It should be noted that, in this document, relational terms such as first and second, etc., are used only to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any actual relationship or order between these entities or operations. Moreover, the terms "comprises," "comprising," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that includes a list of elements includes not only those elements but also other elements not explicitly listed, or elements inherent to such process, method, article, or apparatus.

[0034] Although the embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the invention, and that the scope of the invention is defined by the appended claims and their equivalents.

Claims

1. A digital PCR chip imaging scanner, comprising a housing module (1), an XYZ motion platform module (2) mounted inside the housing module (1), a mounting reference platform (3), and an optical module (4), characterized in that: The XYZ motion platform module (2) and the optical module (4) are respectively arranged at the top and bottom of the mounting reference platform (3), and the Y-axis substrate inside the mounting reference platform (3) is located above the X-axis substrate and is transmission-connected to the stage (5); The front end of the housing module (1) is provided with a discharge trough aligned with the loading platform (5), and a door assembly (6) is installed in the discharge trough, and the door assembly (6) includes a door body (61), a curved plate (62), and a tension spring (63), the two ends of the curved plate (62) are respectively connected to the bottom of the front end of the door body (61) and pass through the discharge trough and are hinged to the inner wall of the housing module (1) through a pin shaft, and the two ends of the tension spring (63) are respectively fixed to one end of the curved plate (62) and the inner wall of the housing module (1); The loading platform (5) can reciprocate and press the transmission door body (61) under the drive of the installation reference platform (3) and move to the outside of the shell module (1) after the door body (61) flips over and gives way. In addition, when the loading platform (5) is installed on the reference platform (3) and the door body (61) is simultaneously subjected to the elastic force of the tension spring (63) and drives the curved plate (62) to reset and close the discharge chute.

2. A digital PCR chip imaging scanner according to claim 1, characterized in that: The inner wall of the front end of the housing module (1) and the rear end structure of the top of the door body (61) are respectively installed with a Hall sensor (65) and a permanent magnet (66), and both sides of the rear end of the top of the door body (61) are equipped with bearings (64) through bearing sleeves, and the bearings (64) can be rollingly connected with the bottom of the loading platform (5) when the loading platform (5) presses the transmission door body (61); The interior of the curved plate (62) is provided with a receiving groove (67) capable of housing the tension spring (63), the front inner wall of the discharge trough is provided with an annular groove (7), and the rear end surface of the door body (61) is fixed with a boss (68) capable of clamping and sealing the annular groove (7).

3. The digital PCR chip imaging scanner according to claim 1, characterized in that: A baffle (11) is provided at the rear end of the loading platform (5), and the baffle (11) is fitted and sealed around the discharge chute at the front end of the housing module (1) after the loading platform (5) is located outside the housing module (1).

4. The digital PCR chip imaging scanner according to claim 1, characterized in that: The loading platform (5) includes a first bracket (51), a second bracket (52), a third bracket (53), and an assembly screw (55). The first bracket (51), the second bracket (52), and the third bracket (53) are sequentially stacked and assembled from top to bottom, and leveling screw holes are provided in the side structures on both sides of the second bracket (52). Leveling screws (54) are provided in the side structures on both sides of the first bracket (51), and one end of the leveling screw (54) can be threadedly connected to the leveling screw hole to adjust the horizontality of the first bracket (51) on the top of the second bracket (52); The second bracket (52) is provided with a first clearance hole in both side structures, the first bracket (51) is provided with a second clearance hole in both side structures, and the third bracket (53) is provided with an assembly screw hole in both side structures, and the first bracket (51) is assembled with the second bracket (52) and the third bracket (53) by sequentially fitting the assembly screws (55) with the first clearance hole and the second clearance hole and then threadedly connecting with the assembly screw holes; An upper magnet (56) is sheathed in the side of the first bracket (51), and a lower magnet (57) capable of being magnetically connected to the upper magnet (56) is sheathed in the side of the second bracket (52).

5. The digital PCR chip imaging scanner according to claim 1, characterized in that: The shell module (1) is internally provided with a PC power module (8), an embedded PC module (9), and a power module (10), and a heat dissipation device is provided in the bottom of the shell module (1), and the heat dissipation device includes a heat dissipation fan. The rear end of the bottom of the shell module (1) and the inner wall of the bottom are respectively provided with ventilation holes (17), a through-shaped step groove, and a connecting notch. The connecting notch is in communication with the step groove space and is clamped with a magnetic dustproof net (14), and the bottom of the shell module (1) is sleeved with a power supply air duct (18) in communication with the ventilation hole (17) space.

6. The digital PCR chip imaging scanner according to claim 5, characterized in that: The magnetic dustproof net (14) is composed of a magnetic stripe frame plate and a filter fixedly nested in the magnetic stripe frame plate, an auxiliary magnetic strip (15) capable of magnetically attracting the magnetic stripe frame plate is fixedly nested on the bottom inner wall of the step groove, and a protruding handle capable of protruding to the outside of the connecting slot is fixed on the surface of the magnetic stripe frame plate. The shell structure at the bottom of the housing module (1) is internally threadedly connected to a limiting screw (16), and the limiting screw (16) can press and limit the side of the magnetic dustproof net (14) and the side of the auxiliary magnetic strip (15).

7. The digital PCR chip imaging scanner according to claim 5, characterized in that: Self-locking holes are provided in the Y-axis substrate and the X-axis substrate inside the XYZ motion platform module (2), and the XYZ motion platform module (2) can be adjusted to zero and align the two self-locking holes, and a self-locking component (12) is provided between the XYZ motion platform module (2) and the mounting reference platform (3); The self-locking component (12) comprises a connecting rod (121) and a steering gear (125); the output end of the steering gear (125) is connected to a disc (124) by transmission; one end of the connecting rod (121) is hingedly mounted to the disc (124) via a pin; the other end of the connecting rod (121) is hingedly mounted to a guide cylinder (123) clamped inside the mounting reference platform (3) via a pin; the guide cylinder (123) is capable of being clamped and limited in sequence with two self-locking holes in an aligned state when the steering gear (125) is sequentially driven through the disc (124) and the connecting rod (121).

8. The digital PCR chip imaging scanner according to claim 7, characterized in that: The interior of the installation reference platform (3) is provided with a guide cylinder (123) capable of being engaged with the limit rod (122), and a fixing seat is installed between the shell surface of the steering gear (125) and the surface of the installation reference platform (3).

9. The digital PCR chip imaging scanner according to claim 1, characterized in that: A buffer flange (13) is installed between the installation reference platform (3) and the bottom of the XYZ motion platform module (2), and the buffer flange (13) is made of soft rubber material; An identification module (22) is installed on the top of the installation reference platform (3), and the identification range of the identification module (22) includes the QR code.

10. The digital PCR chip imaging scanner according to claim 1, characterized in that: The front end of the housing module (1) is provided with an indicator light (19), a power on / off button (20), and an in / out button (21), and the indicator light (19) can reflect the operating status of the housing module (1) by displaying different colors.

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