Compound hydrolyzed whey protein powder capable of preventing sarcopenia and preparation method thereof

Through the combination of five hydrolyzed whey protein powders and specific preparation processes, the problem of in-depth research on hydrolyzed whey protein powder in existing products has been solved, and the effect of effectively preventing sarcopenia is achieved.

CN120501165APending Publication Date: 2025-08-19北京骋和科技有限公司
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Patent Information

Application Number
CN202510802773.X
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-06-16
Publication Date
2025-08-19

AI Technical Summary

Technical Problem

Among the existing muscle-building products, the combination of hydrolyzed whey protein powder is not thorough, the in-depth analysis of core components is lacking, and there are few studies in animal experiments and clinical trials, resulting in less significant muscle-building effect.

Method used

Five different brands of hydrolyzed whey protein powders with hydrolysis levels were used for compounding, mixing in specific proportions, and stirring at low temperature and a certain pressure to prepare a compound hydrolyzed whey protein powder containing specific branched chain amino acid content and molecular weight distribution.

Benefits of technology

Effectively prevent sarcopenia and improve muscle mass in the elderly. Through animal experiments and human experiments, the muscle-building effect of compound hydrolyzed whey protein powder was verified.

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Abstract

The invention belongs to the technical field of biological food, and particularly relates to compound hydrolyzed whey protein powder capable of preventing sarcopenia and a preparation method. The invention discloses compound hydrolyzed whey protein powder capable of preventing sarcopenia. The compound hydrolyzed whey protein powder consists of hydrolyzed whey protein A, hydrolyzed whey protein B, hydrolyzed whey protein C, hydrolyzed whey protein D, hydrolyzed whey protein E, hydrolyzed whey protein F, hydrolyzed whey protein G and hydrolyzed whey protein H. The compound hydrolyzed whey protein powder prepared by the technical scheme has the effect of preventing sarcopenia of old people, and a new idea of compounding hydrolyzed whey protein powder of different brands and different hydrolysis degrees and actual application effect verification are provided.
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Description

Technical Field

[0001] The present invention belongs to the technical field of biological food, and in particular relates to a compound hydrolyzed whey protein powder capable of preventing sarcopenia and a preparation method thereof. Background Art

[0002] Sarcopenia is the natural decrease in muscle mass with age. Typical symptoms include muscle atrophy (such as thinning limbs and decreased grip strength), physical decline (slow walking and difficulty getting up), and fatigue. Early intervention can improve the condition through nutritional supplements and regular exercise.

[0003] Hydrolyzed whey protein is a protein that can enhance human physiological functions. Whey protein is enzymatically broken down into smaller peptide chains or amino acid forms, reducing its molecular weight (the molecular weight of hydrolyzed whey protein is typically 500-5000 Daltons). Advantages of hydrolyzed whey protein: 1. High absorption efficiency: The small molecule structure can be absorbed by the intestines without complex digestion, making it suitable for infants, the elderly, or people with weak digestive functions. 2. Removing allergens while retaining nutrients: The hydrolysis process destroys allergenic components such as β-lactoglobulin in whey protein, reducing the risk of allergies. The key amino acids (such as branched-chain amino acids BCAA) and bioactive peptides of hydrolyzed whey protein are still retained, maintaining its nutritional value. 3. Hydrolyzed whey protein can quickly replenish protein after exercise and promote muscle repair.

[0004] Existing commercially available products claiming muscle-building effects have diverse and complex ingredient compositions, and in-depth research into the core ingredients responsible for these effects is lacking. This is primarily reflected in the lack of in-depth study of the relationship between active substances with significant muscle-building effects and their effective dosages. Regarding muscle-building effects, existing patents for hydrolyzed whey protein remain at the stage of final product development, application, and efficacy verification, lacking in-depth analysis of the efficacy of hydrolyzed whey protein powder raw materials or compounded hydrolyzed whey protein powders. Furthermore, research into compounded hydrolyzed whey protein powders in animal experiments and clinical trials is limited. Summary of the Invention

[0005] The object of the present invention is to provide a compound hydrolyzed whey protein powder and a preparation method for preventing sarcopenia, so as to solve the problems existing in the above-mentioned background technology.

[0006] To achieve the above objectives, this application is implemented through the following technical solutions:

[0007] A compound hydrolyzed whey protein powder for preventing sarcopenia comprises hydrolyzed whey protein A, hydrolyzed whey protein B, hydrolyzed whey protein C, hydrolyzed whey protein D, hydrolyzed whey protein E, hydrolyzed whey protein F, hydrolyzed whey protein G and hydrolyzed whey protein H.

[0008] Furthermore, by weight percentage, the content of each hydrolyzed whey protein in the compound hydrolyzed whey protein powder is 5%-40%, and the total amount is 100%.

[0009] Furthermore, the total branched-chain amino acid content in every 100g of hydrolyzed whey protein A is 13.22g, the total branched-chain amino acid content in every 100g of hydrolyzed whey protein B is 18.39g, the total branched-chain amino acid content in every 100g of hydrolyzed whey protein C is 18.39g, the total branched-chain amino acid content in every 100g of hydrolyzed whey protein D is 19.47g, the total branched-chain amino acid content in every 100g of hydrolyzed whey protein E is 17.87g, the total branched-chain amino acid content in every 100g of hydrolyzed whey protein F is 18.39g, the total branched-chain amino acid content in every 100g of hydrolyzed whey protein G is 23.75g, and the total branched-chain amino acid content in every 100g of hydrolyzed whey protein H is 13.41g.

[0010] Furthermore, in hydrolyzed whey protein A, 18-40% is below 1000 Daltons and the average molecular weight is 3100-3200 Daltons; in hydrolyzed whey protein B, 33-50% is below 1000 Daltons and the average molecular weight is 7000-7100 Daltons; in hydrolyzed whey protein C, >50% is below 1000 Daltons and the average molecular weight is 3500-3650 Daltons; in hydrolyzed whey protein D, >13-30% is below 1000 Daltons and the average molecular weight is 10000-11000 Daltons ; In hydrolyzed whey protein E, >42-60% is below 1000 Daltons, with an average molecular weight of 5000-5500 Daltons; in hydrolyzed whey protein F, >37-58% is below 1000 Daltons, with an average molecular weight of 7000-7500 Daltons; in hydrolyzed whey protein G, >20-60% is below 1000 Daltons, with an average molecular weight of 6500-7000 Daltons; in hydrolyzed whey protein H, >30-60% is below 1000 Daltons, with an average molecular weight of 4500-4700 Daltons.

[0011] Furthermore, in any one type of whey protein hydrolysate, the proportion of whey protein hydrolysate greater than 10,000 Daltons does not exceed 55%.

[0012] A method for preparing a composite hydrolyzed whey protein powder capable of preventing sarcopenia comprises the following steps:

[0013] S1, select hydrolyzed whey protein A, hydrolyzed whey protein B, hydrolyzed whey protein C, hydrolyzed whey protein D, hydrolyzed whey protein E, hydrolyzed whey protein F, hydrolyzed whey protein G and hydrolyzed whey protein H raw materials according to a set ratio;

[0014] S2. Add the selected raw materials into a mixing tank, stir and mix at a constant speed of 1000-2000 rpm for 15 minutes until uniformly dispersed to obtain a composite hydrolyzed whey protein powder.

[0015] Furthermore, step S2 further includes stirring and mixing at a constant speed at a low temperature of -20°C to -10°C and a pressure of 0.3-0.5 MPa.

[0016] The beneficial effects of the present invention are:

[0017] The compound hydrolyzed whey protein powder prepared by this technical solution has the effect of preventing sarcopenia in the elderly, and provides new ideas and practical application effect verification for compounding hydrolyzed whey protein powders of different brands and different degrees of hydrolysis. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 These are the results of the rat grip strength experiment in Examples 1 to 6.

[0019] Figure 2 These are the data for the quadriceps, rectus aestivus, and soleus muscles in Examples 3 and 4.

[0020] Figure 3 This is a human trial data table, where Group A is male and Group B is female.

[0021] Figure 4 This is a table showing the types and contents of amino acids in hydrolyzed whey proteins A to H of the present invention. DETAILED DESCRIPTION

[0022] The technical solutions of the present invention are described in detail below through examples. The following examples are merely exemplary and can only be used to explain and illustrate the technical solutions of the present invention, and cannot be interpreted as limiting the technical solutions of the present invention.

[0023] The present application provides a compound hydrolyzed whey protein powder for preventing sarcopenia, comprising hydrolyzed whey protein A, hydrolyzed whey protein B, hydrolyzed whey protein C, hydrolyzed whey protein D, hydrolyzed whey protein E, hydrolyzed whey protein F, hydrolyzed whey protein G, and hydrolyzed whey protein H. For the hydrolyzed whey proteins A and H, different brands or the same brand can be selected. The key lies in the total branched-chain amino acid content and the molecular weight below 1000 Daltons in the hydrolyzed whey proteins. The above-mentioned hydrolyzed whey proteins A and H in the present application are all commercially available.

[0024] In the present application, the content of each hydrolyzed whey protein in the compound hydrolyzed whey protein powder is 5%-40% by weight, and the total amount is 100%.

[0025] In the present application, the total branched-chain amino acid content in 100g of hydrolyzed whey protein A is 13.22g, the total branched-chain amino acid content in 100g of hydrolyzed whey protein B is 18.39g, the total branched-chain amino acid content in 100g of hydrolyzed whey protein C is 18.39g, the total branched-chain amino acid content in 100g of hydrolyzed whey protein D is 19.47g, the total branched-chain amino acid content in 100g of hydrolyzed whey protein E is 17.87g, the total branched-chain amino acid content in 100g of hydrolyzed whey protein F is 18.39g, the total branched-chain amino acid content in 100g of hydrolyzed whey protein G is 23.75g, and the total branched-chain amino acid content in 100g of hydrolyzed whey protein H is 13.41g. The total branched-chain amino acids include amino acids that cannot be synthesized by the human body.

[0026] In this application, in hydrolyzed whey protein A, 18-40% is below 1000 Daltons and the average molecular weight is 3100-3200 Daltons; in hydrolyzed whey protein B, 33-50% is below 1000 Daltons and the average molecular weight is 7000-7100 Daltons; in hydrolyzed whey protein C, >50% is below 1000 Daltons and the average molecular weight is 3500-3650 Daltons; in hydrolyzed whey protein D, >13-30% is below 1000 Daltons and the average molecular weight is 10000-11000 Daltons ; In hydrolyzed whey protein E, >42-60% is below 1000 Daltons, with an average molecular weight of 5000-5500 Daltons; in hydrolyzed whey protein F, >37-58% is below 1000 Daltons, with an average molecular weight of 7000-7500 Daltons; in hydrolyzed whey protein G, >20-60% is below 1000 Daltons, with an average molecular weight of 6500-7000 Daltons; in hydrolyzed whey protein H, >30-60% is below 1000 Daltons, with an average molecular weight of 4500-4700 Daltons.

[0027] In the present application, the proportion of any hydrolyzed whey protein greater than 10,000 Daltons does not exceed 55%. If this content is exceeded, the total branched-chain amino acid content in the hydrolyzed whey protein will be reduced, thereby affecting the effect of the compound hydrolyzed whey protein powder.

[0028] The present application also provides a method for preparing a composite hydrolyzed whey protein powder capable of preventing sarcopenia, which comprises the following steps:

[0029] S1. Select hydrolyzed whey protein A, hydrolyzed whey protein B, hydrolyzed whey protein C, hydrolyzed whey protein D, hydrolyzed whey protein E, hydrolyzed whey protein F, hydrolyzed whey protein G and hydrolyzed whey protein H according to a set ratio.

[0030] S2. Add the selected raw materials into a mixing tank, stir and mix at a constant speed of 1000-2000 rpm for 15 minutes until uniformly dispersed to obtain a composite hydrolyzed whey protein powder.

[0031] In the present application, step S2 also includes stirring and mixing at a constant speed at a low temperature of -20°C to -10°C and 0.3-0.5 MPa.

[0032] Example 1

[0033] The raw material ratios by weight are: hydrolyzed whey protein A: 30%, hydrolyzed whey protein B: 6%, hydrolyzed whey protein C: 6%, hydrolyzed whey protein D: 30%, hydrolyzed whey protein E: 8%, hydrolyzed whey protein F: 8%, hydrolyzed whey protein G: 6%, and hydrolyzed whey protein H: 6%.

[0034] Example 2

[0035] The raw material ratios by weight are: hydrolyzed whey protein A: 6%, hydrolyzed whey protein B: 30%, hydrolyzed whey protein C: 6%, hydrolyzed whey protein D: 8%, hydrolyzed whey protein E: 30%, hydrolyzed whey protein F: 6%, hydrolyzed whey protein G: 6%, and hydrolyzed whey protein H: 8%.

[0036] Example 3:

[0037] The raw material ratios by weight are: hydrolyzed whey protein A: 5%, hydrolyzed whey protein B: 5%, hydrolyzed whey protein C: 30%, hydrolyzed whey protein D: 5%, hydrolyzed whey protein E: 5%, hydrolyzed whey protein F: 5%, hydrolyzed whey protein G: 5%, and hydrolyzed whey protein H: 40%.

[0038] Example 4:

[0039] The raw material ratios by weight are: hydrolyzed whey protein A: 5%, hydrolyzed whey protein B: 5%, hydrolyzed whey protein C: 40%, hydrolyzed whey protein D: 5%, hydrolyzed whey protein E: 5%, hydrolyzed whey protein F: 5%, hydrolyzed whey protein G: 5%, and hydrolyzed whey protein H: 30%.

[0040] Example 5:

[0041] The raw material ratios by weight are: hydrolyzed whey protein A: 15%, hydrolyzed whey protein B: 15%, hydrolyzed whey protein C: 10%, hydrolyzed whey protein D: 10%, hydrolyzed whey protein E: 10%, hydrolyzed whey protein F: 10%, hydrolyzed whey protein G: 15%, and hydrolyzed whey protein H: 15%.

[0042] Example 6:

[0043] The raw material ratios by weight are: hydrolyzed whey protein A: 10%, hydrolyzed whey protein B: 5%, hydrolyzed whey protein C: 5%, hydrolyzed whey protein D: 5%, hydrolyzed whey protein E: 5%, hydrolyzed whey protein F: 30%, hydrolyzed whey protein G: 30%, and hydrolyzed whey protein H: 10%.

[0044] The experimental results are as follows Figures 1 to 4 shown.

[0045] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention rather than to limit the same. Although the present invention has been described in detail with reference to the preferred embodiments, those skilled in the art should understand that they can still modify or replace the technical solutions of the present invention with equivalents, and these modifications or equivalent replacements cannot cause the modified technical solutions to deviate from the spirit and scope of the technical solutions of the present invention.

Claims

1. A compound hydrolyzed whey protein powder for preventing sarcopenia, characterized in that: It is composed of hydrolyzed whey protein A, hydrolyzed whey protein B, hydrolyzed whey protein C, hydrolyzed whey protein D, hydrolyzed whey protein E, hydrolyzed whey protein F, hydrolyzed whey protein G and hydrolyzed whey protein H.

2. The composite hydrolyzed whey protein powder for preventing sarcopenia according to claim 1, characterized in that: Calculated by weight percentage, the content of each hydrolyzed whey protein in the compound hydrolyzed whey protein powder is 5%-40%, and the total amount is 100%.

3. The composite hydrolyzed whey protein powder for preventing sarcopenia according to claim 1, characterized in that: The total branched-chain amino acid content in every 100g of hydrolyzed whey protein A is 13.22g, the total branched-chain amino acid content in every 100g of hydrolyzed whey protein B is 18.39g, the total branched-chain amino acid content in every 100g of hydrolyzed whey protein C is 18.39g, the total branched-chain amino acid content in every 100g of hydrolyzed whey protein D is 19.47g, the total branched-chain amino acid content in every 100g of hydrolyzed whey protein E is 17.87g, the total branched-chain amino acid content in every 100g of hydrolyzed whey protein F is 18.39g, the total branched-chain amino acid content in every 100g of hydrolyzed whey protein G is 23.75g, and the total branched-chain amino acid content in every 100g of hydrolyzed whey protein H is 13.41g.

4. The composite hydrolyzed whey protein powder for preventing sarcopenia according to claim 1, characterized in that: In hydrolyzed whey protein A, 18-40% is below 1000 Daltons, with an average molecular weight of 3100-3200 Daltons; in hydrolyzed whey protein B, 33-50% is below 1000 Daltons, with an average molecular weight of 7000-7100 Daltons; in hydrolyzed whey protein C, >50% is below 1000 Daltons, with an average molecular weight of 3500-3650 Daltons; in hydrolyzed whey protein D, >13-30% is below 1000 Daltons, with an average molecular weight of 10000-11000 Daltons; In hydrolyzed whey protein E, >42-60% is below 1000 Daltons, with an average molecular weight of 5000-5500 Daltons; in hydrolyzed whey protein F, >37-58% is below 1000 Daltons, with an average molecular weight of 7000-7500 Daltons; in hydrolyzed whey protein G, >20-60% is below 1000 Daltons, with an average molecular weight of 6500-7000 Daltons; in hydrolyzed whey protein H, >30-60% is below 1000 Daltons, with an average molecular weight of 4500-4700 Daltons.

5. The composite hydrolyzed whey protein powder for preventing sarcopenia according to claim 4, characterized in that: The proportion of any whey protein hydrolysate greater than 10,000 Daltons shall not exceed 55%.

6. A method for preparing a composite hydrolyzed whey protein powder capable of preventing sarcopenia, characterized in that: Use the following steps: S1, select hydrolyzed whey protein A, hydrolyzed whey protein B, hydrolyzed whey protein C, hydrolyzed whey protein D, hydrolyzed whey protein E, hydrolyzed whey protein F, hydrolyzed whey protein G and hydrolyzed whey protein H raw materials according to a set ratio; S2. Add the selected raw materials into a mixing tank, stir and mix at a constant speed of 1000-2000 rpm for 15 minutes until uniformly dispersed to obtain a composite hydrolyzed whey protein powder.

7. The method for preparing the composite hydrolyzed whey protein powder capable of preventing sarcopenia according to claim 6, wherein: Step S2 further includes stirring and mixing at a constant speed at a low temperature of -20°C to -10°C and a pressure of 0.3-0.5 MPa.

Citation Information

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