Radiopharmaceutical containment cartridge and method of monitorable containment of technetium instant label pharmaceuticals

Abstract

The present application relates to the technical field of radioactive medicine protection, and discloses a radioactive medicine protection cylinder and a monitorable protection method for technetium instant labeling medicine, which comprises a cylinder body and a cylinder cover installed on the top of the cylinder body, a storage cavity at the top and a driving cavity at the bottom are arranged in the cylinder body, a lead protection layer is arranged in the side wall of the storage cavity, and a mounting disc is arranged in the storage cavity. The activity monitoring assembly arranged on the cylinder body can monitor and display the activity of the sample, which is convenient for the logistics managers or medical staff to check, reduces the operation errors, avoids the frequent rechecking of the activity of the sample by the medical staff, reduces the probability of the medical staff receiving the sample irradiation, is safer, and the vertical driving assembly and the rotary driving assembly can align the sample with the opening, and then the sample is sucked out from the opening through the syringe, so that the sample does not need to be taken out, the contact between the medical staff and the sample is further reduced, and the safety is further improved.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of radioactive medical protection, in particular to a radioactive drug protection cylinder and a monitorable protection method for technetium instant labeling drug. BACKGROUND

[0002] Nuclear medicine technology is a technology for biomedical research and disease diagnosis and treatment using non-natural isotopes (including radioactive isotopes and stable isotopes) and nuclear rays. The technetium instant labeling drug is a commonly used radioactive diagnostic reagent in nuclear medicine, and the core is to label a specific carrier molecule with a radioactive isotope technetium for SPECT (single photon emission computed tomography) imaging. The half-life of the technetium instant labeling drug is short, about 6 hours, and during transportation after preparation, a protection cylinder is often used for transportation. The production personnel places the completed radioactive technetium instant labeling drug into the protection cylinder, and the protection cylinder has a 10mm lead equivalent which can completely block the radioactive source. Then the protection cylinder is packed into a box and sent to a designated hospital by the transportation personnel, and the medical personnel take out the product from the protection cylinder, measure the activity, and then supply it to the patient.

[0003] However, the above protection measures have certain deficiencies. First, the existing protection cylinder only has a shielding effect, and the activity of the drug still needs to be detected by the operator, which increases the probability of the operator contacting the drug, and the safety risk is greater during the process of taking the drug out of the protection cylinder. SUMMARY

[0004] In view of the deficiencies of the prior art, the present application provides a radioactive drug protection cylinder and a monitorable protection method for technetium instant labeling drug, which has the advantages of safety, etc., and solves the problem that the existing protection cylinder only has a shielding effect and still needs to be taken out and detected by the operator, which increases the probability of the operator being irradiated.

[0005] To solve the above technical problems, the present application provides the following technical scheme: a radioactive drug protection cylinder, comprising a cylinder body and a cylinder cover installed on the top of the cylinder body, a storage cavity at the top and a driving cavity at the bottom are arranged in the cylinder body, a lead protection layer is arranged in the side wall of the storage cavity;

[0006] An installation disc is arranged inside the storage cavity, a clamp and a fixing frame are installed on the installation disc, the clamp is used for clamping a non-detection sample, and the fixing frame is used for fixing a detection sample;

[0007] An opening is arranged on the cylinder cover, a screw cap is installed in the opening, and a rotation driving assembly is arranged on the cylinder cover, the rotation driving assembly is used for driving the installation disc to rotate;

[0008] A vertical driving assembly is installed on the cylinder body, and the vertical driving assembly is used for driving the installation disc to move upward;

[0009] The barrel is also provided with an activity monitoring assembly for monitoring and displaying the activity of the detection sample.

[0010] During transportation, the detection sample is fixed on the fixing frame, the non-detection sample is fixed by the clamp, the activity monitoring assembly monitors the activity of the detection sample and displays the activity outside the barrel, after transportation, the vertical driving assembly operates to force the non-detection sample to move to be aligned with the opening, and then the sample is extracted through the opening, and the rotary driving assembly operates to force the mounting disc to rotate to replace different samples.

[0011] Preferably, the activity monitoring assembly comprises an ionization chamber fixed inside the storage cavity, a controller fixed on the outer wall of the barrel, and a storage battery fixed inside the driving cavity.

[0012] Preferably, the mounting disc is provided with a through hole, the fixing frame comprises vertical guide rails located at the edge of the through hole, the vertical guide rails are fixedly connected to the top of the mounting disc, a sliding block is slidably connected inside the vertical guide rails, a tray is fixed on one side of the sliding block, the tray corresponds to the position of the through hole, a vertical screw rod is further arranged inside the vertical guide rails, the vertical screw rod penetrates through the sliding block and is threadedly connected to the sliding block, the vertical screw rod is rotatably connected to the vertical guide rails at both ends, and the top of the vertical screw rod penetrates through the top of the mounting disc and is fixedly connected to a driven gear.

[0013] Preferably, the mounting disc is further provided with a plurality of mounting holes, the mounting holes comprise long-diameter circular holes and short-diameter circular holes which are connected to each other.

[0014] Preferably, the clamp comprises a plurality of clamping blocks which are arranged radially on the surface of the mounting disc and correspond to the positions of the mounting holes, square slot holes are formed in the ends of the clamping blocks away from the mounting holes, square rods are inserted into the square slot holes, one end of the square rod located inside the inner wall of the square slot hole is connected to the inner wall of the square slot hole through a return spring, the other end of the square rod located outside the square slot hole is fixedly connected to the mounting disc, a rotating disc is further rotatably connected to the mounting disc, a volute spring is fixedly connected to the mounting disc at the connection position between the rotating disc and the mounting disc, a plurality of arc-shaped holes are formed on the surface of the rotating disc and are uniformly distributed, and a latch is fixedly connected to the top of each clamping block and is inserted into the arc-shaped hole.

[0015] Preferably, the vertical driving assembly comprises a guide rod, an adjusting screw and a nut seat in the storage cavity, the bottom end of the guide rod is fixed with the bottom wall in the storage cavity, the top end of the guide rod is fixed with an end block, the two ends of the adjusting screw are rotatably connected with the end block and the bottom wall in the storage cavity respectively, the bottom end of the adjusting screw extends into the driving cavity and is fixed with a second bevel gear, the nut seat is threadedly connected with the adjusting screw, the nut seat is also slidably connected with the guide rod, the nut seat penetrates the center of the mounting disc and is rotatably connected with the mounting disc, the vertical driving assembly further comprises a horizontal shaft in the driving cavity, one end of the horizontal shaft is rotatably connected with the side wall of the barrel, the other end of the horizontal shaft is mounted on the inner wall of the driving cavity through a bearing seat, one end of the horizontal shaft is fixed with a first bevel gear, the first bevel gear is engaged with the second bevel gear, and the other end of the horizontal shaft penetrates to the outside of the barrel and is fixed with a side handle.

[0016] Preferably, a positioning hole is formed in the top surface of the mounting disc, and the rotary driving assembly comprises a disc which penetrates and rotates with the barrel cover, the disc is fixed with an upper handle at the top, and the disc is fixed with a positioning rod at the bottom, and the positioning rod is matched with the positioning hole.

[0017] Preferably, an arc-shaped plate is fixed to the inner side wall of the storage cavity, the arc-shaped plate is located above the mounting disc, and a plurality of evenly distributed tooth blocks are arranged on the inner side edge of the arc-shaped plate.

[0018] Preferably, a square slot is formed in the bottom of the screw cover, a square nut sleeve is arranged in the square slot, a water absorption layer is fixedly attached to the bottom end of the square nut sleeve, a bolt is rotatably connected to the top of the screw cover, and the bottom end of the bolt is inserted into the square nut sleeve and threadedly connected therewith.

[0019] The application also discloses a monitoring protection method for technetium instant labeling drugs, which uses the radioactive drug protection barrel.

[0020] Compared with the prior art, the application provides a radioactive drug protection barrel and a monitoring protection method for technetium instant labeling drugs, and has the following beneficial effects:

[0021] 1. The radioactive drug protection barrel and the monitoring protection method for technetium instant labeling drugs can monitor and display the activity of the sample by arranging the activity monitoring assembly on the barrel, which is convenient for the logistics managers or medical staff to check, reduces the operation errors, avoids the medical staff from frequently checking the activity of the sample, reduces the probability of the medical staff being exposed to the sample radiation, is safer, and can align the sample with the opening by the vertical driving assembly and the rotary driving assembly, and then the sample can be sucked out from the opening by the syringe without being taken out, which further reduces the contact between the medical staff and the sample and further improves the safety.

[0022] 2. The radioactive drug protection cylinder and the monitorable protection method for technetium instant labeling drug, through the installation hole and the clamp, a plurality of non-detection samples can be clamped and fixed at the same time, through the fixing frame, the detection sample can be fixed, the stability of the sample in transportation and the stability when the sample is extracted are ensured.

[0023] 3. The radioactive drug protection cylinder and the monitorable protection method for technetium instant labeling drug, through the rotation driving assembly, the operation upper handle can drive the installation disc to rotate, so that different non-detection samples are moved to the bottom of the opening, the samples in different medicine bottles are conveniently sucked out, and through the arc-shaped plate and the fixing frame, when the installation disc rotates, the arc-shaped plate also drives the fixing frame, so that the tray and the detection sample are moved upwards, finally the detection sample and the non-detection sample are consistent in height, the detection sample is conveniently sucked out from the opening.

[0024] 4. The radioactive drug protection cylinder and the monitorable protection method for technetium instant labeling drug, through the screw cap, the bolt on the screw cap is rotated, the square nut sleeve is driven to move downwards along the square groove, so that the water absorption layer contacts the top of the medicine bottle, the water absorption property is used to absorb the drug, the drug is prevented from being exposed on the medicine bottle, the safety in subsequent recycling operation is affected, and the inside of the protection cylinder is also prevented from being polluted. DRAWINGS

[0025] Figure 1 It is a sectional view of a radioactive drug protection cylinder of the present application;

[0026] Figure 2 It is a sectional view of a radioactive drug protection cylinder of the present application;

[0027] Figure 3 It is a sectional view of a vertical driving assembly working state of the present application;

[0028] Figure 4 It is a sectional view of a vertical driving assembly working state of the present application; Figure 3 It is an enlarged view of A part of the present application;

[0029] Figure 5 It is a sectional view of a vertical driving assembly working state of the present application;

[0030] Figure 6 It is a sectional view of a vertical driving assembly working state of the present application;

[0031] Figure 7 It is a sectional view of a vertical driving assembly working state of the present application;

[0032] Figure 8 It is a sectional view of a vertical driving assembly working state of the present application; Figure 7 It is an enlarged view of B part of the present application.

[0033] In the figure: 1, cylinder body; 2, cylinder cover; 21, opening; 22, screw cover; 221, square groove; 222, square nut sleeve; 223, water absorption layer; 224, bolt; 3, storage cavity; 4, driving cavity; 5, mounting disc; 51, through hole; 52, mounting hole; 53, positioning hole; 6, clamp; 61, clamping block; 62, square groove hole; 63, square rod; 64, return spring; 65, rotating disc; 66, spiral spring; 67, arc hole; 68, bolt; 7, fixed frame; 71, guide rail; 72, sliding block; 73, tray; 74, vertical screw; 75, driven gear; 8, rotary drive assembly; 81, disc; 82, upper handle; 83, positioning rod; 9, vertical drive assembly; 91, guide rod; 92, adjusting screw; 93, nut seat; 94, end block; 95, second bevel gear; 96, cross shaft; 97, bearing seat; 98, first bevel gear; 99, side handle; 10, activity monitoring assembly; 101, ionization chamber; 102, controller; 103, battery; 11, arc plate; 12, tooth block. DETAILED DESCRIPTION

[0034] The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, rather than all the embodiments. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative work fall within the scope of protection of the present application.

[0035] As introduced in the background, the deficiencies in the prior art exist, in order to solve the above technical problems, the present application provides a radioactive drug protection cylinder and a monitorable protection method for technetium instant labeling drug.

[0036] Embodiment one: please refer to Figures 1-3 A radioactive drug protection cylinder, comprising a cylinder body 1 and a cylinder cover 2 installed on the top of the cylinder body 1, a storage cavity 3 at the top and a driving cavity 4 at the bottom are arranged in the cylinder body 1, and a lead protection layer is arranged in the side wall of the storage cavity 3;

[0037] An installation disc 5 is arranged inside the storage cavity 3, a clamp 6 and a fixed frame 7 are installed on the installation disc 5, the clamp 6 is used for clamping a non-detection sample, and the fixed frame 7 is used for fixing a detection sample;

[0038] An opening 21, a screw cover 22 installed in the opening 21 and a rotary drive assembly 8 are arranged on the cylinder cover 2, and the rotary drive assembly 8 is used for driving the installation disc 5 to rotate;

[0039] A vertical drive assembly 9 is installed on the cylinder body 1, and the vertical drive assembly 9 is used for driving the installation disc 5 to move upward;

[0040] The barrel 1 is also provided with an activity monitoring assembly 10 for monitoring and displaying the activity of the detection sample;

[0041] During transportation, the detection sample is fixed on the fixing frame 7, the non-detection sample is fixed by the clamp 6, the activity monitoring assembly 10 monitors the activity of the detection sample and displays the activity outside the barrel 1, after transportation, the vertical driving assembly 9 operates to force the non-detection sample to move to be aligned with the opening 21, and then the sample is extracted through the opening 21, and the rotary driving assembly 8 operates to force the mounting disc 5 to rotate to replace different non-detection samples.

[0042] In the embodiment, the sample is a technetium instant marking drug, the barrel 1 is provided as a cylinder, the barrel cover 2 is detachably connected with the edge of the barrel 1, the barrel cover 2 is also provided with a lead protection layer inside, and the screw cover 22 is threadedly connected with the opening 21, in actual application, the components and factory time of the detection sample and the non-detection sample are the same, and the activity of the whole sample is reflected by monitoring the activity of the detection sample;

[0043] In use, the detection medicine is filled in the medicine bottles, then a detection sample is selected from the medicine bottles at random, the remaining medicine bottles are non-detection samples, then the detection sample is installed on the fixing frame 7, the non-detection samples are installed on the mounting disc 5 and fixed by the clamp 6, then the barrel cover 2 is closed to realize closed transportation, during transportation, the activity monitoring assembly 10 monitors the activity of the detection sample on line and displays the activity outside the barrel 1, so that the logistics manager or the medical staff can check in real time, when the sample needs to be taken out, the vertical driving assembly 9 is started to drive the mounting disc 5 to move upward, when the mounting disc 5 moves upward, the detection sample moves upward, so that one of the detection samples is just aligned with the opening 21, then the screw cover 22 is rotated to be opened, the medical staff uses a syringe to suck out the medicine in the medicine bottle, the medicine bottle does not need to be taken out, if other samples need to be sucked out, the rotary driving assembly 8 is started to drive the mounting disc 5 to rotate, so that the other medicine bottles are aligned with the opening 21;

[0044] By providing the activity monitoring assembly 10 on the barrel 1, the activity of the sample can be monitored and displayed, which facilitates the logistics manager or the medical staff to check, reduces the operation error, avoids the medical staff to frequently check the activity of the sample, reduces the probability of the medical staff to accept the sample irradiation, is safer, and by using the vertical driving assembly 9 and the rotary driving assembly 8, the sample can be aligned with the opening 21, and then the sample is sucked out from the opening 21 by the syringe, so that the contact between the medical staff and the sample is further reduced, and the safety is further improved.

[0045] Embodiment two: refer to Figure 3Different from the above embodiment, the activity monitoring assembly 10 comprises an ionization chamber 101 fixed inside the storage cavity 3, a controller 102 fixed on the outer wall of the barrel 1, and a storage battery 103 fixed inside the driving cavity 4.

[0046] The storage battery 103 is used to supply power to the ionization chamber 101 and the controller 102, the controller 102 is provided with a screen for displaying the activity, and in the initial state, the bottom end of the fixing frame 7 extends into the ionization chamber 101, so that the detection sample is located inside the ionization chamber 101, and the detection sample is continuously monitored during transportation. The composition of the detection sample is consistent with that of the non-detection sample, and the time to leave the factory is the same, which can reflect the activity of other samples inside as a whole.

[0047] Embodiment three, refer to Figure 6 Different from the above embodiment, the mounting disc 5 is provided with a through hole 51, the fixing frame 7 comprises a vertical guide rail 71 located at the edge of the through hole 51, the top end of the vertical guide rail 71 is fixedly connected with the mounting disc 5, a sliding block 72 is slidably connected inside the vertical guide rail 71, a tray 73 is fixed on one side of the sliding block 72, the tray 73 corresponds in position to the through hole 51, a vertical screw 74 is further arranged inside the vertical guide rail 71, the vertical screw 74 penetrates through the sliding block 72 and is threadedly connected with the sliding block 72, both ends of the vertical screw 74 are rotatably connected with the vertical guide rail 71, and the top end of the vertical screw 74 penetrates to the top of the mounting disc 5 and is fixedly connected with a driven gear 75.

[0048] The inner cavity of the tray 73 is circular, and the diameter is consistent with that of the medicine bottle. The medicine bottle is inserted into the tray 73 to realize the installation of the medicine bottle. In the initial state, the sliding block 72 and the tray 73 are located at the bottom end of the vertical guide rail 71, and at this time the medicine bottle is located directly below the through hole 51 and inside the ionization chamber 101.

[0049] By arranging the fixing frame 7, the detection sample can be fixed by the tray 73.

[0050] Embodiment four, refer to Figure 6 Figure 8Different from the above-mentioned embodiments, the mounting disc 5 is further provided with a plurality of mounting holes 52, the mounting holes 52 include long diameter circular holes and short diameter circular holes which are communicated with each other, the clamp 6 includes a plurality of clamping blocks 61 which are corresponded to the positions of the mounting holes 52 and are radially arranged on the surface of the mounting disc 5, the clamping block 61 is provided with a square slot hole 62 at the end away from the mounting hole 52, a square rod 63 is inserted into the square slot hole 62, the square rod 63 is connected with the inner wall of the square slot hole 62 at the end of the inner wall of the square slot hole 62 through a reset spring 64, the square rod 63 is fixedly connected with the mounting disc 5 at the end outside the square slot hole 62, the mounting disc 5 is further rotatably connected with a rotating disc 65, the rotating disc 65 is fixedly connected with a spiral spring 66 at the connection position with the mounting disc 5, the surface of the rotating disc 65 is provided with a plurality of arc-shaped holes 67 which are uniformly distributed, the top of each clamping block 61 is fixedly connected with a bolt 68, and the bolt 68 is inserted into the arc-shaped hole 67.

[0051] Among them, the mounting hole 52 is radially arranged, the diameter of the long diameter circular hole is greater than that of the short diameter circular hole, the distance between the long diameter circular hole and the mounting disc 5 is greater than that between the short diameter circular hole and the mounting disc 5, and the end of the clamping block 61 close to the mounting hole 52 is arranged in an arc shape;

[0052] When the non-detection sample is installed, the rotating disc 65 is rotated, the rotating disc 65 drives the spiral spring 66 to deform when rotating, the position of the arc-shaped hole 67 on the rotating disc 65 is changed, thereby pushing the bolt 68 to move, the bolt 68 drives the clamping block 61 to move when moving, the clamping block 61 moves along the square rod 63 and compresses the reset spring 64 at this time, then the medicine bottle is inserted into the long diameter circular hole, the neck of the medicine bottle is clamped in the short diameter circular hole, and then the rotating disc 65 is loosened, the rotating disc 65 is rotated to reset under the elastic force of the spiral spring 66, thereby pushing the clamping block 61 to reset, and the clamping block 61 clamps and fixes the medicine bottle in the short diameter circular hole;

[0053] Through the arrangement of the mounting hole 52 and the clamp 6, a plurality of samples can be clamped and fixed at the same time, thereby ensuring the stability of the samples during transportation and the stability when the samples are extracted.

[0054] Embodiment five, refer to Figures 3-5Unlike the above-mentioned embodiments, the vertical driving assembly 9 comprises a guide rod 91, an adjusting screw rod 92 and a nut seat 93 located in the storage cavity 3, the bottom end of the guide rod 91 is fixed with the bottom wall in the storage cavity 3, the top end of the guide rod 91 is fixed with an end block 94, the two ends of the adjusting screw rod 92 are respectively rotatably connected with the end block 94 and the bottom wall in the storage cavity 3, the bottom end of the adjusting screw rod 92 extends into the driving cavity 4 and is fixed with a second bevel gear 95, the nut seat 93 is threadedly connected with the adjusting screw rod 92, the nut seat 93 is also slidably connected with the guide rod 91, the nut seat 93 penetrates through the center of the mounting disc 5 and is rotatably connected with the mounting disc 5, the vertical driving assembly 9 further comprises a cross shaft 96 located in the driving cavity 4, one end of the cross shaft 96 is rotatably connected with the side wall of the barrel 1, the other end of the cross shaft 96 is mounted on the inner wall of the driving cavity 4 through a bearing seat 97, one end of the cross shaft 96 is fixed with a first bevel gear 98, the first bevel gear 98 is engaged with the second bevel gear 95, the other end of the cross shaft 96 penetrates to the outside of the barrel 1 and is fixed with a side handle 99.

[0055] Wherein, the guide rod 91 is provided as two, the guide rod 91 and the adjusting screw rod 92 are vertically arranged, the end block 94 is fixed with the top end of the two guide rods 91, in use, the side handle 99 is rotated to drive the cross shaft 96 to rotate, the cross shaft 96 drives the first bevel gear 98 to rotate when rotating, the first bevel gear 98 drives the second bevel gear 95 to rotate when rotating, the second bevel gear 95 drives the adjusting screw rod 92 to rotate when rotating, the adjusting screw rod 92 drives the nut seat 93 to move upward when rotating, the nut seat 93 drives the mounting disc 5 to move upward when moving upward, the mounting disc 5 drives the detection sample, the fixing frame 7 and the non-detection sample to move upward when moving upward, so that the non-detection sample moves out of the ionization chamber 101, and finally moves to the bottom of the opening 21, so as to be sucked out of the sample by the syringe subsequently;

[0056] By arranging the vertical driving assembly 9, the mounting disc 5 can be driven to vertically move upward by rotating the side handle 99, thereby driving the sample to move upward, so that the non-detection sample is aligned with the opening 21, and the detection sample can also be separated from the ionization chamber 101, which facilitates the direct suction of the medicine in the medicine bottle from the opening 21, thereby avoiding the opening of the barrel cover 2 and direct contact with the medicine, reducing the radiation injury.

[0057] Embodiment six, refer to Figures 3-6 Unlike the above-mentioned embodiments, the mounting disc 5 is provided with a positioning hole 53 on the top surface, the rotating driving assembly 8 comprises a disc 81, the disc 81 penetrates through the barrel cover 2 and is rotatable with the barrel cover 2, the disc 81 is fixed with an upper handle 82 on the top, the disc 81 is fixed with a positioning rod 83 on the bottom, the positioning rod 83 is matched with the positioning hole 53, the inner side wall of the storage cavity 3 is fixed with an arc-shaped plate 11, the arc-shaped plate 11 is located above the mounting disc 5, and the inner side edge of the arc-shaped plate 11 is provided with a plurality of evenly distributed tooth blocks 12.

[0058] Wherein, the diameter of the positioning hole 53 is larger than the diameter of the positioning rod 83, when the vertical driving assembly 9 is running, the mounting disc 5 moves up until the mounting disc 5 contacts the arc-shaped plate 11, at this time the positioning rod 83 is just inserted into the positioning hole 53, then rotate the upper handle 82 to drive the disc 81 to rotate, the disc 81 drives the positioning rod 83 to rotate when rotating, the positioning rod 83 pushes the mounting disc 5 to rotate around the nut seat 93, the mounting disc 5 drives the non-detection sample and the detection sample to rotate when rotating, so that different non-detection samples move to the opening 21 to suck out the samples in different medicine bottles, when the detection sample rotates with the mounting disc 5, the driven gear 75 contacts the tooth block 12 inside the arc-shaped plate 11 and rolls along the tooth block 12, in turn drives the vertical screw rod 74 to rotate, the vertical screw rod 74 drives the sliding block 72 to move vertically upward when rotating, the sliding block 72 drives the tray 73 to move upward when moving vertically upward, drives the detection sample to move upward, finally the driven gear 75 is separated from the tooth block 12 and no longer rotates, at this time the top of the detection sample penetrates through the through hole 51 in the mounting disc 5 and is consistent in height with other non-detection samples, then the detection sample can also rotate to the bottom of the opening 21 under the action of the rotating driving assembly 8;

[0059] By setting the rotating driving assembly 8 and operating the upper handle 82, the mounting disc 5 can be driven to rotate to move different non-detection samples to the bottom of the opening 21, which facilitates sucking out samples in different medicine bottles, and by setting the arc-shaped plate 11 and the fixed frame 7, the arc-shaped plate 11 also drives the fixed frame 7 to move when the mounting disc 5 rotates, so that the tray 73 and the detection sample move upward, finally the detection sample is consistent in height with the non-detection sample, which facilitates sucking out the detection sample from the opening 21.

[0060] Example seven, refer to Figure 3 Different from the above examples, the bottom of the screw cap 22 is provided with a square groove 221, the square nut sleeve 222 is arranged inside the square groove 221, the water absorption layer 223 is fixedly attached to the bottom end of the square nut sleeve 222, the bolt 224 is rotatably connected to the top of the screw cap 22, and the bottom end of the bolt 224 is inserted into the square nut sleeve 222 and is in threaded connection with the square nut sleeve 222.

[0061] In actual application, when the samples are sucked out from the opening 21 by the syringe, there may be spilling from the bottom end of the syringe, resulting in residual medicine on the top of the medicine bottle, therefore, when the medicine in a certain medicine bottle is sucked out, the screw cap 22 is closed again, and the bolt 224 is rotated, the square nut sleeve 222 is driven to move downward along the square groove 221 when the bolt 224 rotates, so that the water absorption layer 223 contacts the top of the medicine bottle, and the medicine is absorbed by the water absorption, avoiding that the medicine is exposed on the medicine bottle, affecting the safety during the subsequent recycling operation, and also avoiding pollution of the inside of the protective cylinder.

[0062] Example Eight, a method of monitorable containment of technetium instant label drugs using the radiopharmaceutical containment cartridges of the above examples.

[0063] While embodiments of the application have been shown and described, it is to be understood that the application is not limited to the details of the embodiments described, since the scope of the application will be defined with respect to the appended claims and equivalents thereof, which are made a part of this specification.

Claims

1. A radiopharmaceutical protective cylinder, comprising a cylinder body and a cap installed on top of the cylinder body, characterized in that: The cylinder is provided with a storage chamber at the top and a driving chamber at the bottom, and the storage chamber is provided with a lead protective layer on the side wall. The storage cavity is equipped with a mounting plate, on which a clamp and a fixing frame are mounted. The clamp is used to hold non-test samples, and the fixing frame is used to fix test samples. The cylinder cover is provided with an opening, a screw cap installed in the opening, and a rotation drive assembly, the rotation drive assembly being used to drive the mounting plate to rotate. A vertical drive assembly is installed on the cylinder body, which is used to drive the mounting plate to move upward. The cylinder is also equipped with an activity monitoring component, which is used to monitor and display the activity of the test sample. During transportation, the test sample is fixed on the mounting frame, and the non-test sample is fixed by the clamp. The activity monitoring component monitors the activity of the test sample and displays the activity on the outside of the cylinder. After transportation, the vertical drive component operates, forcing the non-test sample to move to align with the opening, and then the sample is extracted through the opening. When the rotation drive component operates, it forces the mounting plate to rotate to replace different samples.

2. The radiopharmaceutical protective casing according to claim 1, characterized in that: The activity monitoring component includes an ionization chamber fixed inside the storage cavity, a controller fixed to the outer wall of the cylinder, and a battery fixed inside the drive cavity.

3. The radiopharmaceutical protective casing according to claim 1, characterized in that: The mounting plate has a through hole on its surface. The fixing frame includes a vertical guide rail located at the edge of the through hole. The top end of the vertical guide rail is fixedly connected to the mounting plate. A slider is slidably connected inside the vertical guide rail. A tray is fixed on one side of the slider. The tray corresponds to the position of the through hole. A vertical screw is also provided inside the vertical guide rail. The vertical screw passes through the slider and is threadedly connected to the slider. Both ends of the vertical screw are rotatably connected to the vertical guide rail. The top end of the vertical screw passes through to the top of the mounting plate and is fixed with a driven gear.

4. The radiopharmaceutical protective casing according to claim 3, characterized in that: The mounting plate surface is also provided with a plurality of mounting holes, including long diameter circular holes and short diameter circular holes that are interconnected.

5. The radiopharmaceutical protective casing according to claim 4, characterized in that: The clamp includes multiple clamping blocks that correspond to the positions of the mounting holes and are radially arranged on the surface of the mounting plate. Each clamping block has a square slot at the end away from the mounting hole. A square rod is inserted into the square slot. The end of the square rod located on the inner wall of the square slot is connected to the inner wall of the square slot through a return spring. The end of the square rod located outside the square slot is fixedly connected to the mounting plate. A turntable is also rotatably connected to the mounting plate. A spiral spring is fixed at the connection between the turntable and the mounting plate. Multiple evenly distributed arc-shaped holes are opened on the surface of the turntable. Each clamping block has a pin fixed to its top, and the pin is inserted into the arc-shaped hole.

6. The radiopharmaceutical protective casing according to claim 5, characterized in that: The vertical drive assembly includes a guide rod, an adjusting screw, and a nut seat located within the storage cavity. The bottom end of the guide rod is fixed to the bottom wall of the storage cavity, and an end block is fixed to the top end of the guide rod. The two ends of the adjusting screw are rotatably connected to the end block and the bottom wall of the storage cavity, respectively. The bottom end of the adjusting screw extends into the drive cavity and is fixed with a second bevel gear. The nut seat is threadedly connected to the adjusting screw and is also slidably connected to the guide rod. The nut seat passes through the center of the mounting plate and is rotatably connected to the mounting plate. The vertical drive assembly also includes a horizontal shaft located within the drive cavity. One end of the horizontal shaft is rotatably connected to the side wall of the cylinder, and the other end of the horizontal shaft is mounted on the inner wall of the drive cavity via a bearing seat. A first bevel gear is fixed to one end of the horizontal shaft, and the first bevel gear meshes with a second bevel gear. The other end of the horizontal shaft extends to the outside of the cylinder and is fixed with a side handle.

7. The radiopharmaceutical protective casing according to claim 1, characterized in that: The mounting plate has a positioning hole on its top surface. The rotary drive assembly includes a disc that passes through the cylinder cover and rotates with the cylinder cover. An upper handle is fixed to the top of the disc, and a positioning rod is fixed to the bottom of the disc. The positioning rod matches the positioning hole.

8. The radiopharmaceutical protective casing according to claim 3, characterized in that: An arc-shaped plate is fixed to the inner wall of the storage cavity. The arc-shaped plate is located above the mounting plate, and multiple evenly distributed toothed blocks are provided on the inner edge of the arc-shaped plate.

9. The radiopharmaceutical protective casing according to claim 1, characterized in that: The bottom of the cap has a square groove, and a square nut sleeve is provided inside the square groove. An absorbent layer is fixedly attached to the bottom end of the square nut sleeve. A bolt is rotatably connected to the top of the cap, and the bottom end of the bolt is inserted into the square nut sleeve and threadedly connected to it.

10. A method for monitoring and protecting against technetium-labeled drugs, characterized in that: The monitorable protection method for this instant-labeled technetium drug uses a radiopharmaceutical protective canister as described in any one of claims 1-9.

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