Negative pressure drug delivery dynamic adjusting device for wound surface and use method of negative pressure drug delivery dynamic adjusting device

Abstract

The invention discloses a negative pressure drug delivery dynamic adjusting device for a wound surface and a using method thereof, and relates to the technical field of medical instruments and equipment.The negative pressure drug delivery dynamic adjusting device comprises a machine shell, a control module, a connecting module, a negative pressure module and a drug delivery module in the wound surface are installed in the machine shell, a collecting chamber is arranged on one side of the bottom of the machine shell, and a pressure stabilizing linkage control mechanism is further arranged in the machine shell; the pressure stabilization linkage control mechanism is used for dynamic regulation and control of negative pressure and drug administration in the wound surface; the connecting module is used for uniform negative pressure of the wound surface and drug administration in the wound surface; according to the scheme, multi-mode free combination is adopted, single negative pressure / in-wound drug delivery, synchronous linkage, reverse linkage and an alternating mode are supported, the full-period requirement from acute trauma to chronic repair is met, and intelligent parameter matching is conducted, for example, through pressure-flow closed-loop feedback, when the negative pressure value rises, the drug delivery flow speed in the wound is automatically reduced, and when the negative pressure value rises, the drug delivery flow speed in the wound is automatically reduced; when wound exudate is reduced, pulse negative pressure is triggered to promote microcirculation.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices and equipment, and in particular to a negative pressure drug delivery dynamic adjustment device for a wound surface and a method for using the device. Background Art

[0002] Negative Pressure Wound Therapy with Instillation (NPWTi) is a treatment method that uses negative pressure suction therapy combined with wound irrigation technology to improve wound infection, improve the preoperative wound bed, and promote wound healing. Negative pressure wound suction technology (NPWT) can greatly improve wound infection by creating a physical negative pressure environment and combining it with local irrigation therapy (Instillation). Negative pressure drainage can remove effusion, bacteria, and secretions, and targeted antibacterial drugs can be infused based on drug sensitivity results. At the same time, the infusion of protease can accurately dissolve necrotic tissue, maximize the protection of normal tissue, and reduce surgical damage. In addition, negative pressure stimulation can promote local vasodilation, enhance basal blood supply, and further promote tissue adhesion and wound contraction. Combined with epidermal growth factor drugs, it can significantly increase the non-surgical healing rate and create favorable conditions for healing.

[0003] However, the existing negative pressure device and the intra-wound drug administration method operate independently of each other and lack a real-time coordinated control mechanism. This separate design leads to two major problems: on the one hand, the parameters of negative pressure and intra-wound drug administration cannot be dynamically matched during the treatment process; when the negative pressure is too high, the drug perfusion cannot completely infiltrate the wound tissue, and after the drug flows out of the irrigation tube, it is quickly sucked out locally by the negative pressure suction sponge, resulting in the wound far away from the irrigation tube being unable to contact the irrigation drug; and when the negative pressure is insufficient, it will cause wound exudate retention. The exudate or drug that cannot be drained in time and effectively will cause the airtightness of the negative pressure device film to be destroyed, thereby interrupting the treatment and causing the negative pressure suction device to fail; on the other hand, in clinical use, in order to avoid the occurrence of the above-mentioned phenomenon, the pressure is often selected to be high rather than low, but in addition to the above-mentioned disadvantages, excessively high pressure will also lead to complications such as local tension blisters around the wound caused by continuous high-pressure suction treatment. In summary, this static treatment model makes it difficult to achieve intelligent feedback regulation of the "pressure-flow" parameters, and cannot meet the dynamic balance requirements of the trinity of "precise exudate management, targeted drug delivery, and promotion of tissue repair" during wound healing.

[0004] In addition, the common negative pressure equipment currently available is a pressure regulating gauge, which adjusts the pressure by connecting the central negative pressure and rotating the valve size. When in use, the negative pressure will be unstable due to the central negative pressure being connected to too many terminal negative pressure devices. The unstable negative pressure will directly lead to the loss of control of the wound negative pressure suction treatment management process. In clinical practice, nurses and patients are often required to observe the parameters of the negative pressure suction device and the negative pressure regulating gauge. There is a lack of a device that can dynamically adjust the negative pressure or maintain a stable negative pressure according to demand. If the negative pressure is too high or too low, an alarm can be used to prompt interventional management.

[0005] Therefore, we propose a negative pressure drug delivery dynamic adjustment device for wound surface and its use method to solve the above problems. Summary of the Invention

[0006] In view of this, the technical problem to be solved by the present invention is to propose a dynamic adjustment device for negative pressure drug delivery in the wound surface and a method of use thereof, so as to solve the problems of dynamic feedback between negative pressure and drug delivery in the wound surface and unstable negative pressure in the prior art.

[0007] To achieve the above-mentioned purpose, the present invention provides the following technical solutions: a device for dynamically adjusting negative pressure drug delivery in a wound surface and a method for using the same, comprising a housing, in which a control module, a connection module, a negative pressure module and a drug delivery module in the wound surface are respectively installed, a collection chamber is provided on one side of the bottom of the housing, and a voltage-stabilizing linkage control mechanism is also provided in the housing; the voltage-stabilizing linkage control mechanism is used for dynamic regulation of negative pressure and drug delivery in the wound surface; the connection module is used for uniform negative pressure and drug delivery in the wound surface.

[0008] Preferably, the negative pressure module includes a negative pressure device, which is installed on the inner wall of the casing. The negative pressure device is connected to a first negative pressure tube, and the first negative pressure tube is fixedly connected to a linkage adjustment block at one end away from the negative pressure device. The bottom of the linkage adjustment block is slidably installed in the casing, and a negative pressure buffer cavity is opened in the middle of the linkage adjustment block. A sliding sleeve is slidably connected to the negative pressure buffer cavity in the middle of the linkage adjustment block. A sealing ring is installed on the outer surface of the sliding sleeve, and the sliding sleeve has a certain sealing performance when sliding with the linkage adjustment block.

[0009] Preferably, a return spring is provided on the inner wall of the negative pressure buffer chamber in the middle of the linkage adjustment block, one end of the return spring is fixed in the negative pressure buffer chamber, and the other end of the return spring is fixedly connected to the sliding sleeve, and a linkage rod is fixedly connected to the middle of the sliding sleeve, and the outer surface of the linkage rod is slidably installed in the middle of the negative pressure buffer chamber of the linkage adjustment block, and the outer surface of the linkage rod is sealed with the negative pressure buffer chamber of the linkage adjustment block.

[0010] Preferably, the negative pressure buffer chamber of the linkage adjustment block is symmetrically provided with negative pressure inlet and outlet holes on the side away from the sliding sleeve, wherein the inlet hole of the negative pressure buffer chamber is connected with the first negative pressure tube, and the outlet hole of the negative pressure buffer chamber is fixedly connected with the second negative pressure tube, and the second negative pressure tube is fixedly connected in the collecting chamber at one end away from the linkage adjustment block, and a driving device is installed on the linkage adjustment block near the bottom of the sliding sleeve, and the driving device is installed on the inner wall of the casing at one end away from the linkage adjustment block; an arc-shaped flexible pressure block is installed on the end of the linkage rod away from the sliding sleeve.

[0011] Preferably, the intra-wound medication module includes an intra-wound medication cover, which is installed on the casing, and the intra-wound medication cover is respectively installed with a pressure regulating and flow rate detection device and a pressure detection device, the pressure regulating and flow rate detection device is used for pressure control of intra-wound medication, and the pressure detection device is used for dynamic intra-wound medication detection of the negative pressure module; an intra-wound medication tube groove is opened on the casing negative pressure module, and an intra-wound medication tube is installed in the intra-wound medication tube groove.

[0012] Preferably, the connection module includes a sealing mold, a rubber plate is installed on one side of the sealing mold, a sponge is installed on the side of the rubber plate away from the sealing mold, capillary drip irrigation is evenly installed in the sponge, one end of the capillary drip irrigation is installed and connected to a liquid inlet pipe, and the other end of the capillary drip irrigation is installed and connected to a liquid outlet pipe.

[0013] Preferably, the capillary drip irrigation is evenly provided with drip holes near the middle of the sponge, the drip holes are arranged to be conical, and the aperture of the drip holes on the outer surface of the capillary drip irrigation is larger than the aperture of the drip holes on the inner wall of the capillary drip irrigation; a diversion negative pressure pipe is connected above the collecting chamber, an electric control valve is installed on the diversion negative pressure pipe, the electric control valve is electrically connected to the control module, and a collecting dish is provided in the collecting chamber, and an arc sliding door is slidably installed on the outside of the collecting chamber, and the arc sliding door is sealed with the collecting chamber.

[0014] A method for using a negative pressure drug delivery dynamic adjustment device for a wound surface, comprising:

[0015] S1, device connection and debugging: correctly connect the negative pressure therapy device to the connection module, ensure that the connection is firm and the seal is good, place the collection dish in the collection chamber, and keep it on the same vertical line with the drug delivery tube in the negative pressure wound surface;

[0016] S2, wound treatment and closure: remove foreign matter from the patient's wound, keep the wound clean, select an appropriate connection module according to the size of the wound, fit the sponge to the wound, and use sealing material to seal the wound and the connection module to ensure good sealing and prevent air leakage;

[0017] S3, equipment startup and monitoring; start the operation control module to start the negative pressure module and the intra-wound drug administration module, start negative pressure drainage and drug infusion, set the negative pressure type and linkage form according to the wound type, and adjust the intra-wound drug administration and negative pressure time at the same time.

[0018] Preferably, the negative pressure types described in S3 include:

[0019] S3.1.1, Negative pressure mode only: The control module controls the pressure regulation and flow rate detection device to squeeze the drug delivery tube in the wound, stopping the delivery of liquid in the drug delivery tube in the wound. The negative pressure mode includes continuous negative pressure and pulsed negative pressure. At the same time, the pressure detection device is activated to dynamically detect and provide feedback on the pressure of the negative pressure module. When the pressure exceeds the preset value range, an alarm prompt is triggered;

[0020] S3.1.2, intra-wound medication mode only: the negative pressure device is controlled by the control module to stop the negative pressure, and at the same time, the pressure regulation and flow rate detection device is controlled to squeeze the intra-wound medication tube, thereby regulating the intra-wound medication flow rate in the intra-wound medication tube.

[0021] Preferably, the linkage form described in S3 includes:

[0022] S3.2.1, Synchronous linkage: The control module controls the negative pressure module and the intra-wound drug delivery module to operate simultaneously, and simultaneously activates the pressure detection device for dynamic detection and feedback of the negative pressure module pressure and the intra-wound drug delivery module intra-wound drug delivery speed;

[0023] S3.2.2, reverse linkage: The control module controls the negative pressure module and the intrawound drug delivery module to operate alternately, and sets the intrawound drug delivery to be suspended when the negative pressure is activated;

[0024] S3.2.3, Alternating mode: The negative pressure module or the intra-wound drug delivery module is independently started in different time periods, and negative pressure or intra-wound drug delivery is performed according to the programmed time period.

[0025] Compared with the prior art, the present invention provides a device for dynamically adjusting negative pressure drug delivery on a wound surface and a method for using the same, which has the following beneficial effects:

[0026] This solution has the following advantages over the existing technology through the linkage control of the intra-wound drug delivery module and the negative pressure module:

[0027] (1) Multimodal dynamic adaptation: The existing negative pressure equipment and intrawound drug delivery device operate independently and cannot be adjusted in real time according to the wound status. This solution adopts a multi-mode free combination: supporting single negative pressure / intrawound drug delivery, synchronous linkage (such as anti-infection, hemostasis), reverse linkage (intrawound drug delivery penetration when negative pressure is paused), alternating mode (time-divided treatment), covering the full cycle needs from acute trauma to chronic repair, and intelligent parameter matching: through pressure-flow closed-loop feedback, for example: when the negative pressure value increases, the intrawound drug delivery flow rate is automatically reduced (to avoid ineffective drug waste), and when the negative pressure value decreases, the intrawound drug delivery flow rate is maintained (to promote effective drug infiltration of the wound), and the interval time is set to trigger pulse negative pressure to promote microcirculation and improve microcirculation around the wound, avoiding long-term pressure treatment that causes pressure damage to the surrounding normal skin tissue (traditional equipment requires manual adjustment).

[0028] (2) This solution controls the extension of the driving device through the control module, and the linkage between the negative pressure and the drug administration in the wound can be regulated by the detection action of the pressure detection device. When the driving device is adjusted to a certain distance, the flow rate in the drug administration tube in the wound can be detected in real time through the monitoring of the pressure detection device; at the same time, the sliding sleeve in the negative pressure buffer cavity of the linkage adjustment block can drive the linkage rod to slide in the linkage adjustment block, and the sliding of the linkage rod can push the arc-shaped flexible pressure block to squeeze the surface of the drug administration tube in the wound. The pressure detection device can be used to control the flow rate of the drug administration tube in the wound by the pressure adjustment and flow rate detection devices. Therefore, through the linkage control of the negative pressure module and the drug administration module in the wound, not only the instability of the negative pressure generated by the negative pressure module can be reduced, but also the waste of drugs caused by excessive liquid flow rate during negative pressure can be reduced.

[0029] (3) Precision targeted treatment: The existing flushing technology combined with negative pressure has limitations and requires manual operation, resulting in a low drug retention rate (about 30-40%). However, this device can achieve timing coordinated control: the "suction-relaxation" cycle of the pulsed negative pressure is synchronized with the drug infusion (such as injecting drugs during the negative pressure interval, the retention rate is increased to more than 70%); and the mechanical stress generated by high-frequency pulsed negative pressure can enhance the discharge of exudate and secretions in previously ineffective drainage areas.

[0030] (4) Dynamic pressure stabilization control. When the negative pressure in the linkage adjustment block generates unstable negative pressure, the suction generated by the negative pressure in the negative pressure buffer chamber of the linkage adjustment block will drive the sleeve to slide in the negative pressure buffer chamber of the linkage adjustment block. At this time, the reset spring begins to be compressed. When the negative pressure changes, the elastic action of the reset spring will push the sleeve in the opposite direction relative to the suction generated by the negative pressure. The sliding sleeve slides in the negative pressure buffer chamber to generate negative pressure compensation in one direction. Therefore, when the negative pressure device generates unstable negative pressure, the action of the negative pressure buffer chamber of the linkage adjustment block can reduce the unstable negative pressure output. BRIEF DESCRIPTION OF THE DRAWINGS

[0031] Figure 1 It is a schematic diagram of the three-dimensional structure of the present invention;

[0032] Figure 2 This is a schematic diagram of the drug delivery state within the wound surface of the three-dimensional structure of the present invention;

[0033] Figure 3 This is an auxiliary schematic diagram of the drug administration state within the wound surface of the three-dimensional structure of the present invention;

[0034] Figure 4 This is a schematic structural diagram of the negative pressure connection module of the present invention;

[0035] Figure 5 A schematic diagram of the structural connection relationship of the voltage stabilizing linkage control mechanism of the present invention;

[0036] Figure 6 This is an auxiliary schematic diagram of the structural connection relationship of the voltage stabilizing linkage control mechanism of the present invention;

[0037] Figure 7 For the present invention Figure 6 Enlarged view of point A in the middle.

[0038] In the picture:

[0039] 1. Casing; 11. Control module; 12. Collection chamber;

[0040] 21. Negative pressure device; 22. First negative pressure pipe; 23. Linkage adjustment block; 24. Sliding sleeve; 25. Return spring; 26. Linkage rod; 27. Driving device; 28. Arc-shaped flexible pressure block; 29. ​​Second negative pressure pipe;

[0041] 31. Intra-wound medication cover; 32. Pressure regulation and flow rate detection device; 33. Pressure detection device; 34. Intra-wound medication tube;

[0042] 41. Sealing mold; 42. Rubber sheet; 43. Sponge; 44. Liquid inlet pipe; 45. Liquid outlet pipe; 46. Capillary drip irrigation. DETAILED DESCRIPTION

[0043] The following will clearly and completely describe the technical solutions in the embodiments of the present invention in conjunction with the accompanying drawings. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0044] Example 1:

[0045] A device for dynamically adjusting negative pressure drug administration in a wound surface and a method for using the device include a housing 1, in which a control module 11, a connection module, a negative pressure module, and a drug administration module in the wound surface are respectively installed. A collection chamber 12 is provided on one side of the bottom of the housing 1. The housing 1 is also provided with a voltage-stabilizing linkage control mechanism; the voltage-stabilizing linkage control mechanism is used for dynamically regulating negative pressure and drug administration in the wound surface; the connection module is used for uniform negative pressure on the wound surface and drug administration in the wound surface.

[0046] Specifically, the negative pressure module includes a negative pressure device 21, which is installed on the inner wall of the casing 1. The negative pressure device 21 is connected to a first negative pressure pipe 22. The first negative pressure pipe 22 is fixedly connected to a linkage adjustment block 23 at one end away from the negative pressure device 21. The bottom of the linkage adjustment block 23 is slidably installed in the casing 1. A negative pressure buffer cavity is opened in the middle of the linkage adjustment block 23. A sliding sleeve 24 is slidably connected to the negative pressure buffer cavity in the middle of the linkage adjustment block 23. A sealing ring is installed on the outer surface of the sliding sleeve 24, and the sliding sleeve 24 has a certain sealing performance when sliding with the linkage adjustment block 23.

[0047] After the negative pressure is generated by the negative pressure device 21, the negative pressure in the negative pressure buffer chamber of the linkage adjustment block 23 is negatively pressurized through the first negative pressure pipe 22. Due to the sealing effect between the sliding sleeve 24 and the linkage adjustment block 23, when negative pressure is generated in the negative pressure buffer chamber of the linkage adjustment block 23, the negative pressure generates a suction force on the sliding sleeve 24, which drives the sliding sleeve 24 to slide to the right in the negative pressure buffer chamber. At this time, the return spring 25 begins to be compressed. It should be noted that the return spring 25 in this solution can be selected according to actual needs.

[0048] This solution utilizes the sliding sleeve 24 to slide in the linkage adjustment block 23. Through the elastic action of the return spring 25, when negative pressure is generated in the linkage adjustment block 23, the negative pressure intensity of the negative pressure device 21 can be detected in real time through the sliding distance of the sliding sleeve 24. The sliding sleeve 24 drives the linkage rod 26 to set the squeezing intensity of the drug delivery tube 34 in the wound. When the negative pressure device 21 is set to different negative pressure intensities, the sliding sleeve 24 drives the linkage rod 26 to squeeze the drug delivery tube 34 in the wound by sliding in the linkage adjustment block 23, so as to dynamically control the flow rate of the liquid in the drug delivery tube 34 in the wound. That is, the greater the negative pressure of the negative pressure device 21, the greater the squeezing intensity of the curved flexible pressing block 28 on the liquid in the drug delivery tube 34 in the wound, and the slower the flow rate. Through the regulation of the pressure regulation and flow rate detection device 32 and the pressure detection device 33, the flow rate of the drug delivery tube 34 in the wound under different negative pressures can be controlled in real time, thereby increasing the linkage between negative pressure and liquid flow and reducing the waste of the wound during negative pressure drug delivery.

[0049] Furthermore, a return spring 25 is provided on the inner wall of the negative pressure buffer chamber in the middle of the linkage adjustment block 23, one end of the return spring 25 is fixed in the negative pressure buffer chamber, and the other end of the return spring 25 is fixedly connected to the sliding sleeve 24, and a linkage rod 26 is fixedly connected to the middle of the sliding sleeve 24. The outer surface of the linkage rod 26 is slidably installed in the middle of the negative pressure buffer chamber of the linkage adjustment block 23, and the outer surface of the linkage rod 26 is sealed with the negative pressure buffer chamber of the linkage adjustment block 23.

[0050] This solution can provide a stable pressure environment for the collection chamber 12 through the design of the linkage adjustment block 23 and the sliding sleeve 24. When the negative pressure generated in the collection chamber 12 is unstable, the elastic action of the reset spring 25 can generate a directional negative pressure effect on the negative pressure cavity of the linkage adjustment block 23, thereby stabilizing the negative pressure and reducing damage to the wound caused by unstable negative pressure.

[0051] The outer surface of the linkage rod 26 slides on the linkage adjustment block 23 and has a certain sealing performance with the linkage adjustment block 23. When the sliding sleeve 24 is subjected to negative pressure, it will drive the linkage rod 26 to start sliding synchronously toward the side close to the first negative pressure tube 22.

[0052] Furthermore, negative pressure inlet and outlet holes are symmetrically opened on the side of the negative pressure buffer chamber of the linkage adjustment block 23 away from the sliding sleeve 24, wherein the negative pressure buffer chamber inlet hole is connected to the first negative pressure tube 22, and the negative pressure buffer chamber outlet hole is fixedly connected to the second negative pressure tube 29. The second negative pressure tube 29 is fixedly connected to the collecting chamber 12 at one end away from the linkage adjustment block 23. A driving device 27 is installed on the linkage adjustment block 23 near the bottom of the sliding sleeve 24, and the driving device 27 is installed on the inner wall of the casing 1 at one end away from the linkage adjustment block 23; an arc-shaped flexible pressing block 28 is installed on the end of the linkage rod 26 away from the sliding sleeve 24;

[0053] Among them, the driving device 27 of this solution can adopt an electric telescopic rod, but it is not limited to the electric telescopic rod. A sliding screw can also be used as a driving source; by adjusting or driving to change the motion path of the driving device 27, the linkage adjustment block 23 can be driven to slide at the bottom of the housing 1. At this time, by adjusting the linkage adjustment block 23 to slide on the housing 1, the negative pressure and the drug administration control in the wound can be changed:

[0054] Specifically, the intra-wound medication module includes an intra-wound medication cover 31, which is mounted on the housing 1. A pressure regulating and flow rate detecting device 32 and a pressure detecting device 33 are installed in the intra-wound medication cover 31. The pressure regulating and flow rate detecting device 32 is used to control the pressure of intra-wound medication, and the pressure detecting device 33 is used for dynamic intra-wound medication detection of the negative pressure module. An intra-wound medication tube groove is provided on the negative pressure module of the housing 1, and an intra-wound medication tube 34 is installed in the intra-wound medication tube groove.

[0055] Among them, the pressure regulating and flow rate detection device 32 and the pressure detection device 33 are both electrically controlled through the collection chamber 12. The pressure detection of the pressure detection device 33 can detect the extrusion strength of the arc-shaped flexible pressure block 28 at the end 36 on the drug delivery tube 34 in the wound. The pressure detection device 33 and the pressure regulating and flow rate detection device 32 can be controlled to adjust the flow rate of the drug delivery tube 34 in the wound under different negative pressures; at the same time, the arc-shaped flexible pressure block 28 adopts a crescent-shaped flexible material to reduce mechanical extrusion damage to the surface of the drug delivery tube 34 in the wound.

[0056] Specifically, the connection module includes a sealing mold 41, a rubber plate 42 is installed on one side of the sealing mold 41, a sponge 43 is installed on the side of the rubber plate 42 away from the sealing mold 41, and capillary drip irrigation 46 is evenly installed in the sponge 43. One end of the capillary drip irrigation 46 is connected to the liquid inlet pipe 44, and the other end of the capillary drip irrigation 46 is connected to the liquid outlet pipe 45.

[0057] Among them, the liquid inlet of the liquid inlet pipe 44 is also connected to the bottom of the drug delivery tube 34 in the wound surface, and the negative pressure port of the liquid outlet pipe 45 is connected to the attached Figure 3 The negative pressure port on the side of the casing 1 is connected.

[0058] The capillary drip irrigation 46 is evenly provided with drip holes near the middle of the sponge 43. The drip holes are set to be conical, and the aperture of the drip holes on the outer surface of the capillary drip irrigation 46 is larger than the aperture of the drip holes on the inner wall of the capillary drip irrigation 46. A diversion negative pressure pipe is connected above the collection chamber 12, and an electric control valve is installed on the diversion negative pressure pipe. The electric control valve is electrically connected to the control module 11, and a collection dish is provided in the collection chamber 12. An arc sliding door is slidably installed on the outside of the collection chamber 12, and the arc sliding door is sealed with the collection chamber 12.

[0059] Example 2, the specific implementation of Example 1 is as follows:

[0060] Step 1: Check the integrity of the equipment;

[0061] Confirm that the negative pressure module including the pressure sensor, the liquid storage tank, the intra-wound drug delivery module including the intra-wound drug delivery pump, the drug solution bag and the intra-wound drug delivery tube 34 are not damaged.

[0062] Check the power / battery status to ensure continued operation of the device.

[0063] Step 2: Dressing and piping installation;

[0064] Cover the patient's wound with a porous biological dressing and connect a Y-type three-way pipe:

[0065] The negative pressure port of the liquid outlet pipe 45 is connected as follows Figure 3 The casing 1 side casing 1 negative pressure tube;

[0066] The liquid inlet tube 44 is connected to the wound surface medication port below the wound surface medication tube 34 and needs to be operated aseptically;

[0067] The specific operating steps are as follows: first, the operator fits the sealing mold 41 as a whole to the middle of the patient's wound, and fits the sponge 43 to the wound. At this time, the medical staff seals the sealing mold 41 to the patient's skin through the dressing under sterile operation to prevent air leakage between the wound and the dressing. To ensure the sealing of the dressing, medical sealant can be applied to prevent air leakage.

[0068] Liquid preparation; negative pressure reservoir: add 50 ml of sterile saline as the initial buffer;

[0069] Connection module; this solution can install an expansion connector above the negative pressure fluid storage tank, which can be used to connect drainage bags of commonly used clinical specifications. The expansion connector is designed and manufactured strictly in accordance with the interface specifications of commonly used clinical drainage containers to ensure that it can be seamlessly, stably and reliably connected to various standard drainage bags widely used on the market; when the negative pressure fluid storage tank needs to be emptied, replaced or maintained, medical staff can quickly and conveniently switch the drainage line to the drainage bag on the expansion connector; this solution ensures that during the period when the fluid storage tank is unavailable, negative pressure suction and drainage fluid collection of the wound can be carried out continuously and uninterruptedly.

[0070] Intra-wound drug delivery module: Prepare drug solutions such as mupirocin solution, growth factor solution, trypsin solution, etc. according to the doctor's instructions, connect the intra-wound drug delivery pipeline and exhaust.

[0071] 2. Basic operation steps;

[0072] Mode selection and parameter setting;

[0073] Operation scenario 1: single mode use of the negative pressure device;

[0074] 1. Negative pressure mode only:

[0075] First, the operator controls the squeezing between the pressure regulating and flow rate detecting device 32 and the drug delivery tube 34 in the wound surface through the control module 11, so that the liquid inside the drug delivery tube 34 in the wound surface stops flowing. At the same time, the negative pressure type (continuous / intermittent / pulse) is set through the control panel of the control module 11.

[0076] First, adjust the negative pressure range (-20 to -150 mmHg). The recommended initial value is:

[0077] (1) When the patient's trauma site is acute trauma: at this time, the control module (11) can be adjusted and the negative pressure value can be set to -100 to -120 mmHg (continuous negative pressure mode);

[0078] (2) When the patient's wound site is a chronic ulcer: At this time, the control module 11 can be adjusted and the negative pressure value of the negative pressure device 21 can be set to -80 mmHg (pulse negative pressure mode, 0.5-1 Hz);

[0079] 2. Intra-wound drug delivery mode only:

[0080] Close the negative pressure module valve and set the intra-wound medication type (continuous / intermittent).

[0081] First, the operator controls the control module 11 to start and stop the negative pressure device 21, and at the same time, the pressure regulating and flow rate detection device 32 is electrically connected to control the squeezing intensity of the drug delivery tube 34 in the wound surface as follows:

[0082] Adjust the flow rate (0.1-1000 ml / h), for example: antibiotic flushing: 10-20 ml / min (intermittent)

[0083] Moisturizer maintenance: 0.5-2 ml / h (continuous)

[0084] The specific process is as follows:

[0085] When the liquid enters the liquid inlet pipe 44 through the drug delivery tube 34 in the wound surface, the liquid will be evenly delivered to the capillary drip irrigation 46 through the liquid inlet pipe 44. Since the capillary drip irrigation 46 is evenly provided with tapered holes, and the outer diameter of the tapered holes is larger, the liquid in the capillary drip irrigation 46 will evenly flow into the sponge 43 through the tapered holes. Since the sponge 43 is in contact with the wound surface, the wound surface can be evenly covered by the action of the liquid in the sponge 43, thereby reducing the problems of incomplete treatment and slow wound healing caused by the local action of the liquid.

[0086] 3. Use linkage mode

[0087] (1) Synchronous linkage (negative pressure and intra-wound drug delivery operate simultaneously):

[0088] Enable the "pressure-flow feedback" function, for example: for every 10 mmHg decrease in negative pressure, the flow rate of drug delivery in the wound increases by 5 ml / h;

[0089] The specific operation process is as follows: first, the operator starts the negative pressure device 21 under the control of the control module 11 and generates negative pressure. Figure 5As shown, at this time, the negative pressure generated by the negative pressure device 21 is transported through the first negative pressure pipe 22 to generate negative pressure in the negative pressure buffer chamber opened by the linkage adjustment block 23. Since the linkage adjustment block 23 and the sliding sleeve 24 have a certain sealing performance, the negative pressure generated in the negative pressure device 21 will produce an unstable negative pressure state. When the negative pressure generates an unstable negative pressure in the linkage adjustment block 23, the suction force generated by the negative pressure in the negative pressure buffer chamber of the linkage adjustment block 23 will drive the sliding sleeve 24 to slide in the negative pressure buffer chamber of the linkage adjustment block 23. At this time, the return spring 25 begins to be compressed. When the negative pressure changes, the elastic action of the return spring 25 will push the sliding sleeve 24 in the opposite direction of the suction force generated by the negative pressure. The sliding sleeve 24 slides in the negative pressure buffer chamber to generate negative pressure compensation in one direction. Therefore, when the negative pressure device 21 generates unstable negative pressure, the negative pressure buffer chamber can reduce the unstable negative pressure output through the linkage adjustment block 23. At this time, the stable negative pressure in the negative pressure buffer chamber will be delivered to the collection chamber 12 through the second negative pressure pipe 29. Since the arc-shaped sliding door in the collection chamber 12 has a certain sealing performance with the collection chamber 12, when the collection dish is placed in the collection chamber 12 and the arc-shaped sliding door is closed, the interior of the collection chamber 12 can also be used as a negative pressure buffer chamber. When negative pressure is gradually generated in the collection chamber 12, the negative pressure will enter the liquid outlet pipe 45 through the negative pressure wound surface drug delivery tube above the collection dish.

[0090] like Figure 4 As shown, at this time, a certain negative pressure will be transported through the liquid outlet pipe 45 to cause the sponge 43 to form a negative pressure fit with the chamber surface, and the liquid generated in the wound will enter through the tapered hole of the capillary drip irrigation 46 under the action of the negative pressure, and the liquid outlet pipe 45 will interact with the negative pressure wound surface drug delivery tube in the housing 1, so that the liquid generated in the wound will flow into the collection dish of the collection chamber 12 with the negative pressure for collection. At the same time, since an electric control valve is installed on the negative pressure wound surface drug delivery tube, the electric control valve is linked to the negative pressure device 21 for control. When the negative pressure of the negative pressure device 21 stops, the electric control valve is closed under the action of electrical control, thereby preventing the backflow of the liquid and reducing secondary cross infection of the liquid.

[0091] At this time, the wound medication port located below the wound medication tube 34 is connected to the liquid inlet pipe 44. At this time, the liquid will be recorded into the capillary drip irrigation 46 through the liquid inlet pipe 44, and will flow into the sponge 43 through the tapered holes of the capillary drip irrigation 46. The sponge 43 will act on the wound surface. At the same time, the negative pressure on the side of the liquid outlet pipe 45 can transport the liquid cleaned by the sponge 43 and the wound surface through the liquid outlet pipe 45 to the collection dish.

[0092] It should be noted that, in this solution, the extension of the driving device 27 is controlled by the control module 11, and the linkage between the negative pressure and the drug administration in the wound can be regulated by the detection action of the pressure detection device 33. When the driving device 27 is adjusted to a certain distance, the flow rate in the drug administration tube 34 in the wound can be detected in real time by monitoring the pressure detection device 33. At the same time, the sliding sleeve 24 in the negative pressure buffer cavity of the linkage adjustment block 23 can drive the linkage rod 26 to slide in the linkage adjustment block 23, and the sliding of the linkage rod 26 can promote the degree of squeezing of the surface of the drug administration tube 34 in the wound by the arc-shaped flexible pressure block 28. The pressure detection device 33 can be used to monitor the flow rate of the drug administration tube 34 in the wound by the pressure adjustment and flow rate detection device 32. Therefore, through the linkage control of the negative pressure module and the drug administration module in the wound, not only the instability of the negative pressure generated by the negative pressure module can be reduced, but also the waste of wound liquid caused by excessive liquid flow rate during negative pressure can be reduced.

[0093] (2) Reverse linkage (negative pressure and intra-wound drug administration alternately):

[0094] Set the device to suspend drug administration in the wound when negative pressure is activated (such as in burn moisturizing scenarios).

[0095] (3) Alternating mode (independent operation in different time periods):

[0096] The control module 11 controls the programmed time period (eg, negative pressure during the day, intra-wound medication at night).

[0097] 3. Operation Process Example (General Scenario)

[0098] Step 1: Turn on the device and select the preset clinical mode (such as "continuous irrigation + pulsed negative pressure" or "intermittent irrigation + continuous negative pressure"), or manually customize the parameters.

[0099] Negative pressure module: Select the negative pressure mode as needed, set the pressure value and frequency (the pulse / intermittent mode requires a time period).

[0100] Intrawound drug delivery module: Select the intrawound drug delivery type, set the flow rate, single infusion volume and interval time.

[0101] Step 2: Run monitoring

[0102] Real-time data monitoring, through the control module 11 screen observation, the negative pressure value fluctuation (normal error ± 5mmHg), through the linkage adjustment block 23 buffer negative pressure chamber can reduce the negative pressure fluctuation value to (± 2mmHg);

[0103] Control the remaining amount of medication and flow rate in the wound, the liquid volume in the reservoir (more than 80% needs to be replaced in time), or an external drainage bag.

[0104] Alarm processing: When pipeline blockage or abnormal drainage volume occurs (there may be active bleeding), the negative pressure suction and drug delivery equipment are suspended, the device connection is checked, and wound treatment is carried out in a timely manner;

[0105] Leak alarm: Reseal the dressing edges and check the tubing connections.

[0106] Abnormal drug delivery within the wound: eliminate air bubbles, drug crystallization or valve failure.

[0107] Step 3: Dynamic Adjustment

[0108] Adjust parameters according to wound response:

[0109] Reduce exudate: reduce negative pressure from -120 mmHg to -80 mmHg and reduce the frequency of intra-wound medication from 3 times a day to 2 times a day.

[0110] Blisters appear around the wound: Immediately stop the negative pressure and check whether the pressure is too high and causing pressure injury.

[0111] Linkage mode switching:

[0112] When the risk of infection increases, switch from "reverse linkage" to "alternating mode" and increase the frequency of antibiotic irrigation.

[0113] Step 4: End of treatment

[0114] Shut down the device sequence:

[0115] First stop the negative pressure module, then close the drug delivery module in the wound (to prevent backflow of the drug solution).

[0116] Pipeline treatment: Close all valves before disconnecting the pipeline and seal the wound interface with a sterile cap.

[0117] The liquid in the negative pressure storage tank should be treated as medical waste, and the drug delivery pipeline in the wound should be discarded.

[0118] Data Records:

[0119] Export operation logs (pressure curve, total amount of drug administration in the wound, alarm records) and archive them in the medical record system;

[0120] Before the equipment is shut down for a long time, empty the liquid storage tank and run the drying program (negative pressure air suction for 30 minutes).

[0121] It should be noted that the term "comprises" or any other variant thereof is intended to cover non-exclusive inclusion, so that a process, method, article, or apparatus that includes a series of elements includes not only those elements, but also includes other elements not explicitly listed, or also includes elements inherent to such process, method, article, or apparatus. In the absence of further limitations, an element defined by the phrase "comprises a ..." does not exclude the presence of other identical elements in the process, method, article, or apparatus that includes the element.

[0122] While embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions, and variations may be made to these embodiments without departing from the principles and spirit of the invention, and that the scope of the invention is defined by the appended claims and their equivalents.

Claims

1. A dynamic adjustment device for negative pressure drug delivery on a wound surface, characterized in that: The invention comprises a housing (1), wherein a control module (11), a connection module, a negative pressure module and an intra-wound drug delivery module are respectively installed in the housing (1); a collecting chamber (12) is provided on one side of the bottom of the housing (1); and a voltage-stabilizing linkage control mechanism is further provided in the housing (1); the voltage-stabilizing linkage control mechanism is used for dynamic regulation of negative pressure and intra-wound drug delivery; and the connection module is used for uniform negative pressure on the wound and intra-wound drug delivery.

2. The device for dynamically adjusting negative pressure drug delivery to a wound surface according to claim 1, characterized in that: The negative pressure module comprises a negative pressure device (21), the negative pressure device (21) is mounted on the inner wall of the casing (1), the negative pressure device (21) is connected to a first negative pressure pipe (22), one end of the first negative pressure pipe (22) away from the negative pressure device (21) is fixedly connected to a linkage adjustment block (23), the bottom of the linkage adjustment block (23) is slidably mounted in the casing (1), a negative pressure buffer cavity is provided in the middle of the linkage adjustment block (23), a sliding sleeve (24) is slidably connected in the negative pressure buffer cavity in the middle of the linkage adjustment block (23), a sealing ring is mounted on the outer surface of the sliding sleeve (24), and the sliding sleeve (24) has a certain sealing performance when sliding with the linkage adjustment block (23).

3. The device for dynamically adjusting negative pressure drug delivery to a wound surface according to claim 2, characterized in that: A reset spring (25) is provided on the inner wall of the negative pressure buffer chamber in the middle of the linkage adjustment block (23), one end of the reset spring (25) is fixed in the negative pressure buffer chamber, and the other end of the reset spring (25) is fixedly connected to the sliding sleeve (24), and a linkage rod (26) is fixedly connected to the middle of the sliding sleeve (24), and the outer surface of the linkage rod (26) is slidably mounted in the middle of the negative pressure buffer chamber of the linkage adjustment block (23), and the outer surface of the linkage rod (26) is sealed with the negative pressure buffer chamber of the linkage adjustment block (23).

4. The device for dynamically adjusting negative pressure drug delivery to a wound surface according to claim 3, characterized in that: The negative pressure buffer chamber of the linkage adjustment block (23) is symmetrically provided with negative pressure inlet and outlet holes on one side away from the sliding sleeve (24), wherein the negative pressure buffer chamber inlet hole is connected to the first negative pressure tube (22), and the negative pressure buffer chamber outlet hole is fixedly connected to the second negative pressure tube (29), and the second negative pressure tube (29) is fixedly connected to the collecting chamber (12) at one end away from the linkage adjustment block (23). The linkage adjustment block (23) is provided with a driving device (27) near the bottom of the sliding sleeve (24), and the driving device (27) is provided with an inner wall of the casing (1) at one end away from the linkage adjustment block (23). The linkage rod (26) is provided with an arc-shaped flexible pressing block (28) at one end away from the sliding sleeve (24).

5. The device for dynamically adjusting negative pressure drug delivery to a wound surface according to claim 1, characterized in that: The intra-wound medication module comprises an intra-wound medication cover (31), which is mounted on a housing (1). A pressure regulating and flow rate detecting device (32) and a pressure detecting device (33) are respectively mounted in the intra-wound medication cover (31). The pressure regulating and flow rate detecting device (32) is used for controlling the pressure of intra-wound medication, and the pressure detecting device (33) is used for dynamic intra-wound medication detection of a negative pressure module. An intra-wound medication pipe groove is provided on the negative pressure module of the housing (1), and an intra-wound medication pipe (34) is mounted in the intra-wound medication pipe groove.

6. The device for dynamically adjusting negative pressure drug delivery to a wound surface according to claim 1, characterized in that: The connection module comprises a sealing mold (41), a rubber plate (42) is installed on one side of the sealing mold (41), a sponge (43) is installed on the side of the rubber plate (42) away from the sealing mold (41), capillary drip irrigation (46) is evenly installed in the sponge (43), one end of the capillary drip irrigation (46) is installed and connected to a liquid inlet pipe (44), and the other end of the capillary drip irrigation (46) is installed and connected to a liquid outlet pipe (45).

7. The device for dynamically adjusting negative pressure drug delivery to a wound surface according to claim 6, characterized in that: The capillary drip irrigation (46) is evenly provided with drip holes near the middle of the sponge (43), and the drip holes are arranged in a conical shape, and the aperture of the drip holes on the outer surface of the capillary drip irrigation (46) is larger than the aperture of the drip holes on the inner wall of the capillary drip irrigation (46). A diversion negative pressure pipe is connected above the collecting chamber (12), and an electric control valve is installed on the diversion negative pressure pipe. The electric control valve is electrically connected to the control module (11), and a collecting dish is provided in the collecting chamber (12). An arc sliding door is slidably installed on the outside of the collecting chamber (12), and the arc sliding door is sealed with the collecting chamber (12).

8. A method for using a dynamic adjustment device for negative pressure drug delivery to a wound surface, applicable to a dynamic adjustment device for negative pressure drug delivery to a wound surface according to any one of claims 1 to 7, characterized in that: include: S1, device connection and debugging; the negative pressure therapy device is correctly connected to the connection module, ensuring that the connection is firm and the seal is good, and the collection dish is placed in the collection chamber (12) and kept on the same vertical line with the drug delivery tube in the negative pressure wound surface; S2, wound treatment and sealing: remove foreign matter from the patient's wound, keep the wound clean, select a suitable connection module according to the size of the wound, fit the sponge (43) to the wound, and use a sealing material to seal the wound and the connection module to ensure good sealing and prevent air leakage; S3, equipment startup and monitoring; start the operation control module (11) to start the negative pressure module and the wound medication module, start negative pressure drainage and drug infusion, set the negative pressure type and linkage form according to the wound type, and adjust the wound medication and negative pressure time at the same time.

9. The method for using the negative pressure drug delivery dynamic adjustment device for wound surface according to claim 8, characterized in that: The negative pressure types described in S3 include: S3.1.1, negative pressure mode only: the control module (11) controls the pressure regulating and flow rate detecting device (32) to squeeze the drug delivery tube (34) in the wound surface, so that the delivery of liquid in the drug delivery tube (34) in the wound surface is stopped, wherein the negative pressure mode includes continuous negative pressure and pulsed negative pressure; S3.1.2, only intra-wound medication mode: the negative pressure device (21) is controlled by the control module (11) to stop the negative pressure, and at the same time, the pressure regulating and flow rate detection device (32) is controlled to squeeze the intra-wound medication tube (34), thereby regulating the intra-wound medication flow rate in the intra-wound medication tube (34).

10. The method for using the negative pressure drug delivery dynamic adjustment device for wound surface according to claim 8, characterized in that: The linkage forms described in S3 include: S3.2.1, Synchronous linkage: The control module (11) controls the negative pressure module and the intra-wound medication module to operate simultaneously, and simultaneously starts the pressure detection device (33) for dynamic detection and feedback of the pressure of the negative pressure module and the medication speed of the intra-wound medication module; S3.2.2, reverse linkage: the negative pressure module and the intra-wound medication module are controlled by the control module (11) to operate alternately, and the intra-wound medication is suspended when the negative pressure is started; S3.2.3, Alternating mode: The negative pressure module or the intra-wound drug delivery module is independently started in different time periods, and negative pressure or intra-wound drug delivery is performed according to the programmed time period.

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