Traditional Chinese medicine compound tablet for treating osteosarcoma and preparation method thereof

By optimizing traditional Chinese medicine compound tablets with modern pharmaceutical technology, the problems of high toxicity, low bioavailability, poor targeting, and unreasonable dosage form of traditional Chinese medicine prescriptions in the treatment of osteosarcoma have been solved, achieving a more efficient and safer treatment effect for osteosarcoma.

CN120789205APending Publication Date: 2025-10-17YUNNAN HUANGJIA MEDICAL CIRCLE INST OF TRADITIONAL CHINESE MEDICINE
0 Cites 0 Cited by

Patent Information

Application Number
CN202511207058.8
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-08-27
Publication Date
2025-10-17

AI Technical Summary

Technical Problem

Traditional Chinese medicine prescriptions have problems in the treatment of osteosarcoma, such as high toxicity, low bioavailability, poor targeting, unstable active ingredients and unreasonable dosage forms, which affect efficacy and safety.

Method used

Modern pharmaceutical technology is used to optimize traditional Chinese medicine compound tablets, including enzymatic detoxification of Aconitum carmichaelii and Aconitum kusnezoffii, nano-processing of natural copper, freeze-drying and ultra-fine pulverization of scorpion and centipede, and the use of bone-targeting carrier hydroxyapatite-hyaluronic acid complex, combined with water extraction, alcohol extraction and volatile oil extraction, to prepare stable and targeted traditional Chinese medicine compound tablets.

Benefits of technology

It significantly reduces the toxicity of traditional Chinese medicine compound tablets, improves bioavailability and targeting, enhances drug accumulation and efficacy at bone tumor sites, ensures the stability of active ingredients and dosage form, and improves safety and ease of use.

✦ Generated by Eureka AI based on patent content.
Patent Text Reader

Abstract

The invention discloses a traditional Chinese medicine compound tablet for treating osteosarcoma and a preparation method of the traditional Chinese medicine compound tablet, the tablet takes a Huanghome medicine circle osteosarcoma basic formula as a core, is prepared from 18 medicinal materials such as rhizoma pleionis, berba aristolochiae mollissimae, angelica sinensis and the like, and is optimized by a modern pharmaceutical technology. The preparation method comprises the following steps: performing enzymolysis and detoxification on radix aconiti and radix aconiti kusnezoffii, performing nanocrystallization on natural copper, performing freeze-drying-superfine grinding on insect medicines, extracting other medicinal materials, mixing, combining with a bone targeting carrier, and tabletting. The invention solves the problems of high toxicity, low bioavailability, poor targeting property and the like of the traditional prescription, has the advantages of obvious toxicity reduction, obvious synergism, stable active components, optimized dosage form, compliance of process and the like, and is suitable for treating osteosarcoma.
Need to check novelty before this filing date? Find Prior Art