Marrow washing pill for treating chronic diseases caused by cold toxin and damp toxin and application thereof

Abstract

The invention discloses a marrow washing pill for treating chronic diseases caused by cold toxin and damp toxin and application of the marrow washing pill, and belongs to the field of traditional Chinese medicines. The marrow washing pill is prepared from scorpion, centipede, stiff silkworm, selfheal, bighead atractylodes rhizome, poria cocos, cassia twig, liquorice and the like, and rhizoma alismatis, polyporus umbellatus and the like can be added or reduced according to illness conditions. According to the holism concept and the yin-yang five-element theory, the traditional Chinese medicine composition plays a role by removing cold toxin and damp toxin and regulating viscera functions. The raw material medicines are specifically processed to prepare the pill, and the pill can be used for treating various chronic diseases such as breast nodules, arthritis and the like. Clinical verification shows that the total effective rate reaches 95%, and the traditional Chinese medicine composition has the advantages of remarkable curative effect, high safety, strong adaptability and the like, and provides an effective scheme for treatment of related chronic diseases.

Description

Technical Field

[0001] The present invention relates to Xisui Pills, specifically to a kind of Xisui Pills for treating chronic diseases caused by cold toxin and damp toxin and its application. Background Art

[0002] Cold toxin and damp toxin are important etiological factors for various chronic diseases in traditional Chinese medicine theory. Cold toxin stagnation is likely to cause qi and blood stasis, leading to symptoms such as joint pain and nodular hyperplasia; damp toxin viscosity hinders the transportation and transformation of zang-fu organs, aggravating discomfort such as limb heaviness and swelling. The two often intertwine, resulting in a prolonged course of disease and repeated attacks. Chronic diseases such as breast nodules, rheumatoid arthritis, and lumbar diseases seriously affect the quality of life of patients.

[0003] Currently, clinical treatment mostly adopts symptomatic treatment: Western medicines mainly focus on anti-inflammatory, analgesic, and softening and dissipating nodules, but long-term use is likely to produce side effects such as gastrointestinal reactions and liver and kidney function damage, and it is difficult to eradicate the cause; although traditional Chinese medicine prescriptions pay attention to overall conditioning, there are problems such as fixed prescriptions and lack of targeted syndrome differentiation and addition and subtraction, and the curative effect on complex syndromes is limited.

[0004] At the same time, the existing drugs have insufficient synergistic effect in removing cold toxin and damp toxin, often only focusing on a single pathogenic factor, and it is difficult to achieve radical treatment. Therefore, developing a drug that can accurately target cold toxin and damp toxin, take into account syndrome differentiation and treatment, has high safety and long-lasting curative effect has become the key requirement for solving the treatment problems of such chronic diseases. Summary of the Invention

[0005] The technical problem to be solved by the present invention is to overcome the above-mentioned technical defects and provide a kind of Xisui Pills for treating chronic diseases caused by cold toxin and damp toxin and its application.

[0006] To solve the above technical problem, the technical solution provided by the present invention is a kind of Xisui Pills for treating chronic diseases caused by cold toxin and damp toxin and its application: it is composed of the following raw materials in parts by weight: scorpion 3 - 8g, centipede 1 - 5 pieces, bombyx batryticatus 5 - 20g, prunella vulgaris 5 - 20g, atractylodes macrocephala 5 - 20g, poria cocos 5 - 20g, cassia twig 1 - 10g, licorice 1 - 10g.

[0007] As an improvement, it also includes raw materials for addition and subtraction according to symptoms, and the raw materials for addition and subtraction according to symptoms are selected from one or more of alisma orientale, polyporus umbellatus, ligusticum wallichii, pheretima aspergillum, cortex lycii radicis, fructuskochiae scopariae, cortex dictamni radicis, and hirudo nipponica.

[0008] As an improvement, the chronic disease is a disease caused by cold toxin and damp toxin.

[0009] As an improvement, the diseases caused by cold toxins and dampness toxins include nodular diseases and joint diseases; wherein, the nodular diseases are selected from one or more of breast nodules, pulmonary nodules, cerebral infarction, myocardial infarction, and varicose veins; and the joint diseases are selected from one or more of arthritis, rheumatoid arthritis, cervical spondylosis, and lumbar spondylosis.

[0010] The preparation method of Suidan includes the following steps: weighing each raw material according to the stated weight proportions, mixing them, pulverizing them, sieving them, and making them into pills.

[0011] Application of Xisui Dan in the preparation of medicines for treating chronic diseases caused by cold and dampness toxins.

[0012] As an improvement, the chronic diseases include nodular diseases and joint diseases; wherein the nodular diseases are selected from one or more of breast nodules, pulmonary nodules, cerebral infarction, myocardial infarction, and varicose veins; and the joint diseases are selected from one or more of arthritis, rheumatoid arthritis, cervical spondylosis, and lumbar spondylosis.

[0013] The advantages of this invention compared to existing technologies are as follows: the Marrow Cleansing Pill and its application have multiple beneficial effects. It can treat chronic diseases caused by cold and dampness toxins at their root cause. Through the synergistic effect of multiple herbs, it removes toxins and regulates the internal organs and qi and blood, with a total effective rate of 95%, and the therapeutic effect is long-lasting and not prone to recurrence.

[0014] The treatment plan follows the principles of Yin-Yang and Five Elements theory, and differentiates treatment based on syndrome differentiation. Medication is adjusted according to the patient's syndrome type to adapt to individual differences and enhance the targeted nature of the treatment. The dosage of raw materials is scientifically controlled, and standardized processing reduces toxicity. The addition of licorice ensures high safety, with no significant adverse reactions observed in clinical practice.

[0015] Balancing traditional efficacy with modern pharmacology, this formula embodies the characteristics of traditional Chinese medicine while also possessing scientific evidence to enhance its credibility. Standardized processing enhances efficacy and facilitates the storage and transportation of the preparation. With a wide range of applications, it covers various nodular and joint diseases, providing an effective treatment option for chronic diseases and demonstrating high clinical value.

[0016] The Marrow Cleansing Pill has significant benefits for chronic diseases caused by cold and dampness toxins. Its scientific formula can specifically treat nodular and joint diseases such as breast nodules and arthritis, activate cells, dispel pathogens and stagnation, and improve related symptoms.

[0017] Simultaneously, it can regulate the body, enhance immunity, and prevent disease, while also possessing health-preserving, weight-loss, and beauty-enhancing effects. Following the holistic approach to diagnosis, the main prescription can be flexibly adjusted to suit various conditions and improve efficacy. Furthermore, it is available in multiple dosage forms, including pills and powders, to cater to different needs and is highly practical.

[0018] The Marrow Cleansing Pill is highly effective in treating chronic diseases caused by cold and dampness toxins, demonstrating remarkable efficacy in "preventing disease before it occurs, treating disease early, and preventing its progression during treatment."

[0019] When preventing illness before it occurs, Atractylodes macrocephala and Poria cocos strengthen the spleen and dispel dampness, reducing the accumulation of damp toxins; Cinnamomum cassia warms and unblocks the meridians, dispelling cold toxins. People prone to breast nodules, arthritis, and other conditions can improve their internal environment, enhance their resistance to cold and damp toxins, and reduce the likelihood of developing these conditions after taking this medicine.

[0020] In terms of early treatment of existing diseases, it can play a role in the early stages of the disease. For example, in the early stages of pulmonary nodules, scorpions, centipedes, and silkworms can clear the meridians and disperse nodules to help them dissipate; in the early stages of rheumatoid arthritis, prunella vulgaris clears heat and reduces swelling, while licorice harmonizes the effects of other herbs, relieving pain and controlling the condition in a timely manner.

[0021] The treatment and prevention of complications rely on the advantages of adjusting the prescription according to the symptoms. When dampness and toxins cause edema, Alisma plantago-aquatica and Polyporus umbellatus are added to enhance diuresis and eliminate dampness, preventing the spread of dampness and toxins and the occurrence of complications. When there is significant blood stasis, Ligusticum chuanxiong and Hirudo medicinalis are added to promote blood circulation and remove blood stasis, preventing the condition from worsening and developing into cerebral infarction, myocardial infarction, etc. At the same time, it stabilizes the condition of breast nodules, lumbar spine disease, etc., and prevents them from deteriorating. Detailed Implementation

[0022] To facilitate understanding of this application, a more comprehensive description will be provided below.

[0023] A kind of marrow-washing pill for treating chronic diseases caused by cold and dampness toxins and its application, is composed of the following raw materials in parts by weight: scorpion 3-8g, centipede 1-5 pieces, silkworm 5-20g, prunella vulgaris 5-20g, atractylodes macrocephala 5-20g, poria cocos 5-20g, cinnamon twig 1-10g, and licorice 1-10g.

[0024] It also includes raw materials that can be added or subtracted according to symptoms, wherein the raw materials that can be added or subtracted according to symptoms are selected from one or more of Alisma plantago-aquatica, Polyporus umbellatus, Ligusticum chuanxiong, Pheretima aspergillum, Lycium chinense root bark, Kochia scoparia fruit, Dictamnus dasycarpus root bark, and Hirudo medicinalis.

[0025] The chronic diseases mentioned are those caused by cold toxins and dampness toxins.

[0026] The diseases caused by cold toxins and dampness toxins include nodular diseases and joint diseases; wherein, the nodular diseases are selected from one or more of breast nodules, pulmonary nodules, cerebral infarction, myocardial infarction, and varicose veins; and the joint diseases are selected from one or more of arthritis, rheumatoid arthritis, cervical spondylosis, and lumbar spondylosis.

[0027] The preparation method of Suidan includes the following steps: weighing each raw material according to the stated weight proportions, mixing them, pulverizing them, sieving them, and making them into pills.

[0028] Application of Xisui Dan in the preparation of medicines for treating chronic diseases caused by cold and dampness toxins.

[0029] The chronic diseases include nodular diseases and joint diseases; wherein, the nodular diseases are selected from one or more of breast nodules, pulmonary nodules, cerebral infarction, myocardial infarction, and varicose veins; and the joint diseases are selected from one or more of arthritis, rheumatoid arthritis, cervical spondylosis, and lumbar spondylosis.

[0030] I. Overall Concept of the Plan:

[0031] The Marrow Cleansing Pill described in this invention is guided by a holistic view, believing that the human body is an organic whole. When cold and damp toxins invade the body, they are not confined to a specific area but affect the functions of all organs through the meridians and the flow of Qi and blood. The development of chronic diseases is a result of the intertwining of stagnant cold and sticky damp toxins, leading to poor Qi and blood circulation and an imbalance of Yin and Yang in the organs. Therefore, the Marrow Cleansing Pill does not treat a single symptom but rather aims to eliminate the root causes of cold and damp toxins, regulate the Qi, blood, Yin and Yang of the whole body, and restore the coordination of organ functions, thereby achieving the therapeutic goal of "cleansing away the root causes of all diseases."

[0032] II. Theoretical support based on Yin-Yang and Five Elements theory:

[0033] From the perspective of Yin-Yang and Five Elements theory, cold toxins belong to Yin evils and easily damage Yang Qi; dampness toxins also belong to Yin evils and easily obstruct the flow of Qi. When these two invade the human body, they can lead to an imbalance of Yin and Yang—excessive Yin evils damage Yang Qi, manifesting as symptoms of Yang deficiency such as aversion to cold, cold limbs, and fatigue; at the same time, dampness toxins trap the spleen (belonging to the Earth element), affecting the spleen's transportation and transformation functions, leading to abnormal water and dampness metabolism and exacerbating the accumulation of dampness toxins; cold toxins stagnate in the liver (belonging to the Wood element) and tendons, causing joint contractures and pain; dampness toxins obstruct the lungs (belonging to the Metal element), leading to the formation of nodules.

[0034] In the Marrow Cleansing Pill, cinnamon twig belongs to yang, which warms and unblocks the meridians to dispel cold toxins and help yang qi rise; atractylodes macrocephala and poria cocos strengthen the spleen (earth) and promote diuresis, restore the spleen's digestive function, and cut off the source of damp toxins; prunella vulgaris clears liver fire (wood) and disperses stagnation, targeting nodular diseases; scorpion and centipede circulate and unblock the meridians, break up stagnation, and harmonize qi and blood; licorice harmonizes all the medicines, so as to balance yin and yang and coordinate the five elements.

[0035] III. Characteristics and Pharmacological Analysis of the Active Pharmaceutical Ingredient

[0036] Scorpion: pungent in taste, neutral in nature, and poisonous; it enters the liver meridian. It has the effects of calming wind and relieving spasms, clearing the meridians and relieving pain, and attacking toxins and dispersing nodules. Modern pharmacological research shows that its scorpion venom can inhibit platelet aggregation, improve blood circulation, and has a certain alleviating effect on cerebral infarction and myocardial infarction caused by thrombosis. It can also reduce inflammatory responses and relieve joint pain.

[0037] Centipede: It has a pungent taste, warm nature, and is poisonous. It enters the liver meridian. Its effects are similar to those of scorpion, but its ability to unblock meridians and promote circulation is stronger. It can break up blood stasis and has a significant effect on improving the stagnation state of varicose veins and nodular diseases (such as breast nodules and lung nodules).

[0038] Silkworm pupae: Salty and pungent in taste, neutral in nature, and enters the liver, lung, and stomach meridians. It has the effects of calming wind and relieving spasms, dispelling wind and relieving pain, and resolving phlegm and dissipating nodules. Its protein and amino acids can regulate immune function, inhibit nodule growth, and alleviate the inflammatory response of rheumatoid arthritis.

[0039] Prunella vulgaris: pungent and bitter in taste, cold in nature, and enters the liver and gallbladder meridians. It can clear liver heat, improve eyesight, and reduce swelling. Modern research shows that its active ingredients can inhibit tumor cell proliferation, have a certain therapeutic effect on breast nodules and lung nodules, and can also lower blood pressure and improve vascular circulation.

[0040] Atractylodes macrocephala: sweet and bitter in taste, warm in nature, and enters the spleen and stomach meridians. It has the effects of strengthening the spleen and replenishing qi, drying dampness and promoting diuresis. Its volatile oil can promote gastrointestinal motility, enhance the spleen's digestive function, and reduce the generation of dampness and toxins. It is often used for spleen and stomach weakness caused by dampness and toxins.

[0041] Poria cocos: sweet and bland in taste, neutral in nature, and enters the heart, lung, spleen, and kidney meridians. It can promote diuresis and eliminate dampness, strengthen the spleen and calm the mind. Its polysaccharide components can enhance immunity and promote water metabolism. When combined with Atractylodes macrocephala, it enhances the effect of drying dampness and promoting diuresis, relieving symptoms such as edema and joint effusion caused by dampness and toxins.

[0042] Cinnamon twig: pungent and sweet in taste, warm in nature, and enters the heart, lung, and bladder meridians. It has the functions of inducing sweating and relieving muscle tension, warming and unblocking the meridians, and assisting yang and qi circulation. Its volatile oil components can dilate blood vessels, promote blood circulation, dispel cold toxins, and relieve joint pain and meridian obstruction caused by the stagnation of cold toxins.

[0043] Licorice: Sweet in taste, neutral in nature, and enters the heart, lung, spleen, and stomach meridians. It can tonify the spleen and replenish qi, clear heat and detoxify, resolve phlegm and relieve cough, relieve spasms and pain, and harmonize the effects of other herbs. The glycyrrhizic acid it contains has anti-inflammatory and anti-allergic effects, can reduce the toxicity of scorpions and centipedes, and enhance the overall efficacy of the formula.

[0044] Adjust the dosage of raw materials according to symptoms:

[0045] Alisma plantago-aquatica and Polyporus umbellatus: enhance the diuretic and dampness-removing effects, suitable for those with severe damp-heat and edema;

[0046] Chuanxiong: It invigorates blood circulation, promotes qi circulation, dispels wind and relieves pain. It is suitable for patients with cerebral infarction and cervical spondylosis with obvious blood stasis.

[0047] Earthworm: Clears heat and calms the nerves, unblocks the meridians and relieves asthma; suitable for rheumatoid arthritis with red, swollen, hot and painful joints.

[0048] Lycium chinense root bark, Kochia scoparia fruit, and Dictamnus dasycarpus root bark: clear heat and dampness, dispel wind and relieve itching, suitable for skin diseases caused by dampness and toxins;

[0049] Leeches: They break up blood stasis, promote menstruation, and eliminate masses. They are suitable for patients with severe varicose veins and pulmonary nodules.

[0050] IV. Data Validation:

[0051] To verify the efficacy of the Marrow Cleansing Pill of this invention, 120 patients with chronic diseases caused by cold and dampness were selected for clinical observation. Among them, 60 patients had nodular diseases (breast nodules, pulmonary nodules, cerebral infarction, myocardial infarction, varicose veins) and 60 patients had joint diseases (arthritis, rheumatoid arthritis, cervical spondylosis, lumbar spondylosis). The course of disease in all patients was more than 6 months.

[0052] Treatment method: The basic formula described in claim 1 is used, and the formula is modified according to the patient's specific symptoms as described in claim 2. The marrow-washing pill is prepared according to the method of claim 5. It is taken 3 times a day, 5g each time, for 3 consecutive months.

[0053] Criteria for evaluating therapeutic efficacy:

[0054] Significant effect: Symptoms are significantly improved, nodules shrink by more than 50%, joint pain disappears, and mobility returns to normal;

[0055] Effective: Symptoms are reduced, nodules shrink by 30%-50%, joint pain is relieved, and mobility is improved;

[0056] Ineffective: Symptoms remain unchanged or worsen.

[0057] Results: Of the 120 patients, 78 (65%) showed significant improvement, 36 (30%) showed improvement, and 6 (5%) showed no improvement, with a total effective rate of 95%. Among them, 40 patients with nodular diseases showed significant improvement, 18 showed improvement, and 2 showed no improvement; 38 patients with joint diseases showed significant improvement, 18 showed improvement, and 4 showed no improvement. No significant adverse reactions were observed in any patient.

[0058] V. Purpose and Methods of Processing:

[0059] Purpose of processing:

[0060] Toxicity Reduction: Scorpions and centipedes are poisonous, but processing can reduce the toxic components and ensure safe use.

[0061] Enhanced efficacy: For example, the warming and invigorating effect of cinnamon twigs is stronger after being stir-fried, and the nodule-dispersing effect of prunella vulgaris is milder after being honey-fried.

[0062] Facilitates formulation: After processing, the medicinal material has a loose texture, making it easy to crush and sieve, thus improving the uniformity of the pills.

[0063] Preparation method:

[0064] Scorpions: Take clean scorpions, wash them with clean water, drain them, put them in a pot, stir-fry over low heat until slightly yellow, remove and let cool. Stir-frying can reduce toxicity and enhance the effects of clearing the meridians and relieving pain.

[0065] Centipede: Take a cleaned centipede, remove the head and legs, mix it with rice wine, let it soak until thoroughly moistened, place it in a stir-frying container, stir-fry over low heat until slightly charred, remove and let cool. The rice wine preparation reduces toxicity and enhances the blood-activating and stasis-removing effects.

[0066] Silkworm pupae: Take clean silkworm pupae, stir-fry them with wheat bran until the surface turns yellow, remove and sift out the wheat bran, then let cool. Stir-frying with wheat bran can moderate the medicinal properties and enhance the effects of resolving phlegm and dissipating nodules.

[0067] Prunella vulgaris: Take clean Prunella vulgaris, place it in a stir-frying container, stir-fry over low heat until slightly charred, then remove and let cool. Stir-frying reduces its bitter and cold properties, preventing damage to the spleen and stomach.

[0068] Atractylodes macrocephala: Take clean Atractylodes macrocephala slices, stir-fry with wheat bran until the surface turns yellowish-brown, remove and sift out the wheat bran, then let cool. Stir-frying with wheat bran can enhance its spleen-strengthening and dampness-drying effects.

[0069] Poria cocos: Take clean Poria cocos, separate them by size, soak them in water until thoroughly soaked, remove them, steam them until the moisture inside and outside is uniform, slice them, and sun-dry them. Slicing facilitates the dissolution of active ingredients.

[0070] Cinnamon twigs: Take clean cinnamon twig sections, place them in a stir-frying container, and stir-fry over low heat until the surface is slightly charred. Remove and let cool. Stir-frying enhances the warming and meridian-clearing effects.

[0071] Licorice: Take clean licorice slices, mix them with honey, let them soak thoroughly, place them in a stir-frying container, and stir-fry over low heat until they turn yellow to dark yellow and no longer sticky. Remove and let cool. Honey-frying can enhance the effects of tonifying the spleen and replenishing qi, as well as relieving spasms and pain.

[0072] VI. Differentiation of Syndromes and Treatment:

[0073] This invention, the Marrow Cleansing Pill, is for chronic diseases caused by cold and dampness toxins. The formula needs to be modified according to the patient's specific syndrome pattern.

[0074] For cases of predominant cold-toxin syndrome, the symptoms include aversion to cold, cold limbs, pain that worsens with cold, pale tongue with a white and greasy coating. The dosage of cinnamon twig can be increased to 8-10g in the basic formula, and 3-6g of prepared aconite can be added to enhance the cold-dispelling effect.

[0075] For dampness-heat syndrome, symptoms include heaviness in the limbs, edema, and a thick, greasy tongue coating. Add 10-15g of Alisma plantago-aquatica and 10-15g of Polyporus umbellatus to the basic formula, and increase Atractylodes macrocephala and Poria cocos to 15-20g to enhance the diuresis.

[0076] Significant blood stasis syndrome: characterized by hard nodules, fixed pain, and a purplish-dark tongue. Add 8-12g of Ligusticum chuanxiong and 3-5g of leech (after processing) to enhance the effect of promoting blood circulation and removing blood stasis.

[0077] For heat-toxin syndrome: symptoms include red, swollen, hot and painful joints and burning nodules. Add 8-12g of earthworm and 10-15g of Lycium chinense root bark to clear heat-toxin.

[0078] Spleen and stomach deficiency syndrome: manifested as poor appetite, fatigue and loose stools. The amount of Atractylodes macrocephala and Poria cocos in the basic formula is increased to 15-20g, and the licorice is honey-processed. Codonopsis pilosula is added to 10-15g to strengthen the spleen and replenish qi.

[0079] Root cause treatment, with significant and lasting effects:

[0080] This invention, guided by a holistic approach, does not treat individual symptoms but directly addresses the common root cause of chronic diseases: cold and dampness toxins. Through the synergistic effect of multiple medicinal ingredients, it not only eliminates existing cold and dampness toxins in the body but also regulates organ function and improves blood circulation, fundamentally cutting off the pathways for the generation and accumulation of these toxins. Clinical data verification shows a total effective rate of up to 95%, with good efficacy for nodular diseases (such as breast nodules and pulmonary nodules) and joint diseases (such as arthritis and cervical spondylosis), and a significant efficacy rate of 65%. The treatment effect is stable and long-lasting, with a low recurrence rate.

[0081] Following the principles of Yin-Yang and Five Elements theory and syndrome differentiation, it has strong adaptability:

[0082] The treatment plan is based on the theory of Yin and Yang and the Five Elements, fully considering the interrelationships between the internal organs and the balance of Yin and Yang. It achieves harmony of Yin and Yang and coordination of the Five Elements through the combination of cinnamon twig to warm Yang and dispel cold, and atractylodes and poria to strengthen the spleen and eliminate dampness. At the same time, it emphasizes syndrome differentiation and treatment, allowing for adjustments based on the patient's specific symptoms, such as a predominance of cold toxicity, damp toxicity, or significant blood stasis. For example, increasing the dosage of cinnamon twig for severe cold toxicity and adding alisma and polyporus for severe damp toxicity, ensures the formula is precisely tailored to individual patient differences, improving the targetedness and effectiveness of the treatment.

[0083] The active pharmaceutical ingredients are scientifically formulated and have high safety profile.

[0084] The dosages of each ingredient in the basic formula have been scientifically selected. Doses ranging from 3-8g of scorpion and 1-5 centipedes ensure efficacy while minimizing toxicity risks. Furthermore, standardized processing methods (such as simmering the scorpion over a low flame and processing the centipedes in rice wine) further reduce the toxicity of potentially toxic ingredients. Clinical observations showed no significant adverse reactions in any patients, effectively ensuring safety. In addition, the addition of licorice not only harmonizes the effects of the other ingredients but also, due to its glycyrrhizic acid content, reduces the toxicity of scorpion and centipede, further enhancing medication safety.

[0085] IV. Combining traditional efficacy with modern pharmacology, leveraging complementary advantages:

[0086] This invention adheres to traditional Chinese medicine theory, reflecting the specific effects of the raw materials (such as scorpion's ability to unblock meridians and relieve pain, and prunella vulgaris's ability to disperse nodules and reduce swelling), while also incorporating modern pharmacological research findings to confirm the scientific validity of each raw material component (such as scorpion venom improving blood circulation, and the active ingredients of prunella vulgaris inhibiting tumor cell proliferation). This combination of tradition and modernity ensures the theoretical foundation of the formula while providing modern scientific evidence for its efficacy, thus enhancing the credibility and persuasiveness of the approach.

[0087] Standardized processing methods improve efficacy and ease of preparation.

[0088] Through targeted processing, not only can toxicity be reduced and efficacy enhanced (such as stir-frying Atractylodes macrocephala with wheat bran to enhance the spleen-strengthening and dampness-drying effects, and processing Glycyrrhiza uralensis with honey to enhance the spleen-tonifying and qi-boosting effects), but the texture of the medicinal materials can also be made loose, making them easier to pulverize and sieve, improving the uniformity and stability of the pills, and facilitating the storage, transportation and clinical application of the drugs.

[0089] It has a wide range of applications and high clinical value.

[0090] This invention can be used to treat a variety of chronic diseases caused by cold and dampness toxins, covering nodular diseases (breast nodules, pulmonary nodules, cerebral infarction, myocardial infarction, varicose veins, etc.) and joint diseases (arthritis, rheumatoid arthritis, cervical spondylosis, lumbar spondylosis, etc.), with a wide range of applications. Its holistic regulation and root-cause treatment characteristics provide a new and effective solution for the treatment of chronic diseases, possessing high clinical application value and promising prospects for wider application.

[0091] The Marrow Cleansing Pill demonstrates significant and multi-dimensional beneficial effects in addressing chronic diseases caused by cold and dampness toxins, specifically in the following aspects:

[0092] First, its targeted treatment effects are outstanding. Its core formula combines medicinal herbs such as scorpion, centipede, and silkworm, which have detoxifying, meridian-clearing, softening, and nodule-dispersing effects, with ingredients like prunella vulgaris, atractylodes macrocephala, and poria cocos, which clear heat, dry dampness, strengthen the spleen, and dispel dampness. This precisely targets the root causes of various chronic diseases caused by cold and dampness toxins. For nodular diseases such as breast nodules and lung nodules, it can activate cells, promote cell vitality, dissipate nodules, and clear blockages. For joint diseases such as arthritis and rheumatoid arthritis, it can effectively dispel cold toxins, resolve dampness, relieve pain, and improve joint function. It also has a good therapeutic effect on related conditions such as cerebral infarction, myocardial infarction, varicose veins, cervical spondylosis, and lumbar spondylosis.

[0093] Secondly, it possesses comprehensive preventative and health-preserving value. By regulating the body's overall functions and enhancing cell vitality, Xi Sui Dan fundamentally improves the body's resistance and self-healing abilities. It not only treats existing chronic diseases but also effectively prevents various illnesses caused by the invasion of cold and dampness toxins. Simultaneously, its spleen-strengthening, dampness-removing, and qi-blood-regulating effects are significant in health preservation. Long-term, reasonable use can improve physical condition and also has slimming and beautifying effects, achieving the dual benefits of treating illness and maintaining health.

[0094] Furthermore, it embodies the advantages of holistic diagnosis and flexible adaptation. This formula follows the concept of holistic diagnosis, not limiting itself to the treatment of a single symptom, but rather addressing complex chronic diseases from the perspective of regulating the body's Qi, blood, Yin, and Yang, and eliminating pathogenic factors. In addition, the main formula can be modified with great flexibility. Besides the previously mentioned Alisma plantago-aquatica, Polyporus umbellatus, and Ligusticum chuanxiong, which can be added or subtracted according to symptoms, the types and dosages of medications can be further adjusted based on the patient's specific condition and constitution, making the treatment more personalized and targeted, and significantly improving its adaptability and efficacy for different diseases.

[0095] Finally, diversified dosage forms enhance practicality and applicability. The preparation of Xisui Dan is not limited to a single pill; it can also be formulated into powders, liquids, and tinctures, among other dosage forms, according to clinical needs and patient habits. Each dosage form has its advantages; for example, powders are easy to carry and take, liquids have a rapid onset of action, and tinctures are better suited to the release of blood-activating and stasis-removing components, meeting the needs of different populations and improving the drug's practicality and accessibility.

[0096] In terms of preventing disease before it occurs, the Atractylodes macrocephala and Poria cocos in Xisui Dan can strengthen the spleen and remove dampness, reducing the retention of damp toxins in the body; Cinnamomum cassia can warm and unblock the meridians and dispel cold toxins. For people prone to chronic diseases caused by cold and damp toxins, such as breast nodules, arthritis, and cervical spondylosis, taking this medicine can improve the body's internal environment, enhance the body's resistance to cold and damp toxins, thereby reducing the incidence of these chronic diseases and playing a role in preventing disease before it occurs.

[0097] For early treatment of existing diseases, Xi Sui Dan (a traditional Chinese medicine formula) can be effective in the early stages of various chronic diseases caused by cold and dampness toxins. For example, for early-stage pulmonary nodules, scorpions, centipedes, and silkworms have the effect of clearing the meridians and dispersing nodules, helping them to dissipate. For early-stage rheumatoid arthritis, Prunella vulgaris can clear heat and reduce swelling, while licorice can harmonize the effects of other herbs, relieving joint pain and other discomfort, and timely controlling the progression of the disease, thus achieving early treatment.

[0098] In terms of treatment and prevention of complications, Xi Sui Dan (a traditional Chinese medicine formula) allows for the adjustment of raw materials according to the patient's specific symptoms, effectively preventing the condition from worsening or developing complications. If the patient has severe dampness and edema, adding Alisma plantago-aquatica and Polyporus umbellatus can enhance the diuretic and dampness-removing effects, preventing further spread of dampness and toxicity and the development of other complications. If the patient has significant blood stasis, adding Ligusticum chuanxiong and Hirudo medicinalis can invigorate blood and remove blood stasis, preventing the condition from worsening and leading to serious diseases such as cerebral infarction and myocardial infarction. Simultaneously, for nodular diseases such as breast nodules and varicose veins, and joint diseases such as lumbar spondylosis, Xi Sui Dan can stabilize the condition during treatment, preventing it from progressing to a more serious state, demonstrating its beneficial effect of preventing complications during treatment.

[0099] The present invention and its embodiments have been described above, and such description is not restrictive.

Claims

1. A Marrow Cleansing Pill for treating chronic diseases caused by cold and dampness toxins, characterized in that: It is composed of the following raw materials in parts by weight: 3-8g scorpion, 1-5 centipedes, 5-20g silkworm, 5-20g prunella vulgaris, 5-20g atractylodes macrocephala, 5-20g poria cocos, 1-10g cinnamon twig, and 1-10g licorice.

2. The Marrow Cleansing Pill according to claim 1 for treating chronic diseases caused by cold and dampness toxins, characterized in that: It also includes raw materials that can be added or subtracted according to symptoms, wherein the raw materials that can be added or subtracted according to symptoms are selected from one or more of Alisma plantago-aquatica, Polyporus umbellatus, Ligusticum chuanxiong, Pheretima aspergillum, Lycium chinense root bark, Kochia scoparia fruit, Dictamnus dasycarpus root bark, and Hirudo medicinalis.

3. The Marrow Cleansing Pill according to claim 1 for treating chronic diseases caused by cold and dampness toxins, characterized in that: The chronic diseases mentioned are those caused by cold toxins and dampness toxins.

4. The Marrow Cleansing Pill according to claim 3 for treating chronic diseases caused by cold and dampness toxins, characterized in that: The diseases caused by cold toxins and dampness toxins include nodular diseases and joint diseases; wherein, the nodular diseases are selected from one or more of breast nodules, pulmonary nodules, cerebral infarction, myocardial infarction, and varicose veins; and the joint diseases are selected from one or more of arthritis, rheumatoid arthritis, cervical spondylosis, and lumbar spondylosis.

5. A method for preparing the Marrow Cleansing Pill as described in any one of claims 1-4, characterized in that: Includes the following steps: Weigh each raw material according to the stated weight proportions, mix them, pulverize them, sieve them, and prepare the pills.

6. The use of the Xisui Dan as described in any one of claims 1-4 in the preparation of a medicine for treating chronic diseases caused by cold toxins and damp toxins.

7. The application according to claim 6, characterized in that: The chronic diseases include nodular diseases and joint diseases; wherein, the nodular diseases are selected from one or more of breast nodules, pulmonary nodules, cerebral infarction, myocardial infarction, and varicose veins; and the joint diseases are selected from one or more of arthritis, rheumatoid arthritis, cervical spondylosis, and lumbar spondylosis.