Composition for preventing hair loss and strengthening roots, hair lotion and preparation method of hair lotion

Abstract

The invention belongs to the technical field of daily necessities, and particularly relates to a composition for preventing hair loss and strengthening roots, a hair lotion and a preparation method of the hair lotion. The composition comprises the following components in parts by mass: 15-20 parts of an eucalyptus globulus leaf extract, 18-23 parts of a coconut meat extract, 6-10 parts of a ramulus et folium uncariae cum uncis extract, 10-18 parts of a podocarpus macrophyllus extract, 20-25 parts of a lemon leaf extract, 3-5 parts of a rose extract and 5-10 parts of a sorghum leavening, and the substances are specifically compounded, so that scalp blood vessels can be expanded, and the scalp blood vessels can be effectively treated. According to the present invention, with the composition, the hair loss prevention and root strengthening effects are provided, the scalp blood supply is increased, the scalp microcirculation is improved, the more nutrition is provided for the hair follicle so as to enhance the hair follicle vitality, and the composition is beneficial to the reduction of the head oxidative stress and the inflammatory reaction so as to achieve the hair loss prevention and root strengthening effects. Therefore, the composition provided by the invention can be used for preparing hair loss preventing and / or root strengthening products.

Description

Technical Field

[0001] This invention belongs to the field of daily necessities technology, specifically relating to a composition and hair shampoo for preventing hair loss and strengthening hair roots, and a method for preparing the same. Background Technology

[0002] Hair is an important part of a person's appearance and is closely related to their image. For men, hair loss can lead to a receding hairline, resulting in a "Mediterranean" hairstyle, making the face look older; for women, thinning hair can make them lose their feminine charm and affect their self-confidence.

[0003] With increasing life pressures, more and more people are suffering from hair loss, making anti-hair loss products a hot research topic in this field. For example, Chinese Patent CN 118662418 B discloses a natural plant extract composition for preventing hair loss and strengthening hair, its preparation method, and its application. It reveals that through the synergistic effect of a rationally proportioned combination of seven plant extracts—including St. John's wort extract, Guaiac extract, Thunbergia odorifera pericarp extract, Mango leaf extract, Polygonum multiflorum extract, Platycladus orientalis leaf extract, and ginger extract—it effectively inhibits 5α-reductase, a key enzyme that causes seborrheic alopecia, and major microorganisms such as Malassezia furfur, Propionibacterium acnes, and Staphylococcus aureus, thereby reducing the probability of seborrheic alopecia. The beneficial components in these seven plant extracts promote blood circulation and regulate scalp sebum secretion, promoting hair growth and improving the scalp environment. Furthermore, the Mango leaf extract and Polygonum multiflorum extract are rich in vitamins and nutrients, nourishing the hair, enhancing its elasticity and shine, and reducing breakage and hair loss. For example, Chinese patent CN 117530901 B describes the preparation of a hair product using one or more of the following ingredients: Polygonum multiflorum, Sapindus mukorossi, ginger, Sophora flavescens, olive leaf, Coptis chinensis root, ginseng, and Platycladus orientalis leaf. This product nourishes the hair roots, effectively promoting hair growth, preventing hair loss, and strengthening hair. However, research on the preparation of hair shampoos using Eucalyptus globulus leaves, coconut meat, and Uncaria rhynchophylla as raw materials has not yet been reported. Summary of the Invention

[0004] The purpose of this invention is to provide a composition and hair shampoo for preventing hair loss and strengthening hair roots, and a method for preparing the same, which have the characteristics of preventing hair loss and strengthening hair roots.

[0005] This invention provides a composition for preventing hair loss and strengthening hair roots, comprising, by weight parts, the following components: 15-20 parts of eucalyptus leaf extract, 18-23 parts of coconut meat extract, 6-10 parts of Uncaria rhynchophylla extract, 10-18 parts of Podocarpus macrophyllus extract, 20-25 parts of lemon leaf extract, 3-5 parts of rose extract, and 5-10 parts of sorghum ferment.

[0006] Preferably, the composition comprises the following components in parts by weight: 15 parts of eucalyptus leaf extract, 22 parts of coconut meat extract, 8 parts of Uncaria rhynchophylla extract, 10 parts of Podocarpus macrophyllus extract, 20 parts of lemon leaf extract, 5 parts of rose extract, and 5 parts of sorghum fermentation product.

[0007] This invention provides a method for preparing the composition described in the above technical solution, comprising the following steps: The leaves of Eucalyptus globulus, Uncaria rhynchophylla, Podocarpus macrophyllus, and lemon leaves were respectively mixed with ethanol solution, heated, concentrated and dried to obtain Eucalyptus globulus leaf extract, Uncaria rhynchophylla extract, Podocarpus macrophyllus extract and lemon leaf extract. Coconut meat and rose were mixed with water and then subjected to low-temperature ultrasonic extraction, solid-liquid separation and vacuum concentration to obtain coconut meat extract and rose extract. After soaking sorghum in water, add Lactobacillus plantarum and carry out aerobic fermentation, solid-liquid separation and low-temperature concentration and drying to obtain sorghum fermentation product; The extracts of eucalyptus leaves, Uncaria rhynchophylla, Podocarpus macrophyllus, lemon leaves, coconut meat, rose, and sorghum fermentation were mixed evenly to obtain a composition.

[0008] Preferably, the mass-to-volume ratio of the eucalyptus leaves, Uncaria rhynchophylla, Podocarpus macrophyllus, lemon leaves, and ethanol solution is 1g:10-12mL. The volume concentration of the ethanol solution is 90%-95%.

[0009] Preferably, the heating conditions include a temperature of 90-100℃ and a time of 35-45 minutes.

[0010] Preferably, the mass-to-volume ratio of the coconut meat, rose petals, and water is 1:18-25mL. The conditions for low-temperature ultrasonic extraction include: temperature of 30-35℃, time of 2-3 hours, and power of 100-120Hz.

[0011] Preferably, the mass ratio of sorghum, water, and Lactobacillus plantarum is 1:40-50:0.05-0.1; The effective viable count of *Lactobacillus plantarum* is ≥0.5 × 10⁻⁶. 7 cfu / g.

[0012] Preferably, the conditions for the mixed soaking include: a temperature of 30-35°C and a time of 30-40 minutes; The conditions for the aerobic fermentation include: a temperature of 42-45℃ and a time of 3-4 hours.

[0013] The present invention provides the application of the composition described in the above technical solution in the preparation of hair loss prevention and / or root strengthening products.

[0014] This invention provides a hair shampoo for preventing hair loss and strengthening hair roots, the hair shampoo comprising the composition described in the above technical solution.

[0015] Beneficial effects: This invention provides a composition for preventing hair loss and strengthening hair roots. By weight, the composition comprises the following components: 15-20 parts of eucalyptus leaf extract, 18-23 parts of coconut meat extract, 6-10 parts of Uncaria rhynchophylla extract, 10-18 parts of Podocarpus macrophyllus extract, 20-25 parts of lemon leaf extract, 3-5 parts of rose extract, and 5-10 parts of sorghum ferment.

[0016] This invention involves a specific compounding of eucalyptus leaf extract, coconut meat extract, Uncaria rhynchophylla extract, Podocarpus macrophyllus extract, lemon leaf extract, rose extract, and sorghum fermentation product. This composition helps dilate scalp blood vessels, increase blood supply to the scalp, improve scalp microcirculation, provide more nutrients to hair follicles, and thus enhance hair follicle vitality. Furthermore, this composition helps reduce oxidative stress and inflammation in the scalp, thereby achieving the effects of preventing hair loss and strengthening hair roots. Therefore, the composition provided by this invention can be used in the preparation of products for preventing hair loss and / or strengthening hair roots. Detailed Implementation

[0017] To further illustrate the present invention, the solutions provided by the present invention will be described in detail below with reference to the embodiments, but they should not be construed as limiting the scope of protection of the present invention.

[0018] Blue gum trees ( Eucalyptus Globulus Leaves, Uncaria rhynchophylla ( Cryptolepis buchananii ), Podocarpus macrophyllus ( Podocarpus macrophyllus ),lemon( Citrus limon (L.) Burmann f. Wash, dry, and grind the leaves, coconut meat (from Wenchang coconuts), roses, and sorghum for later use. The particle size of each ground material should be ≤0.1cm.

[0019] Example 1 The steps for preparing a composition for preventing hair loss and strengthening hair roots are as follows: (1) The composition comprises the following components in parts by weight: 15 parts of eucalyptus leaf extract, 22 parts of coconut meat extract, 8 parts of Uncaria rhynchophylla extract, 10 parts of Podocarpus macrophyllus extract, 20 parts of lemon leaf extract, 5 parts of rose extract and 5 parts of sorghum ferment.

[0020] (2) The preparation process is as follows: The crushed eucalyptus leaves were mixed with a 95% ethanol solution at a mass-volume ratio of 1g:10mL and heated at 95℃ for 35min to obtain an extract. The extract was filtered to obtain a filtrate, which was then concentrated under reduced pressure to recover the solvent and obtain a concentrate. The concentrate was then dried in an oven at 40℃ to obtain the eucalyptus leaf extract. The preparation methods for Uncaria rhynchophylla extract, Podocarpus macrophyllus extract, and lemon leaf extract are the same as those for the preparation method of Eucalyptus globulus leaf extract. The crushed coconut meat was mixed with water at a mass-to-volume ratio of 1:20 mL and then extracted by low-temperature ultrasonication at 35℃ and 120Hz for 2 hours to obtain an extract. The extract was then subjected to solid-liquid separation to obtain a filtrate. The filtrate was then vacuum concentrated to 1 / 3 of its original volume at 60℃ and -0.06MPa to obtain the coconut meat extract. The preparation method of rose extract is the same as that of coconut meat extract described above; Crushed sorghum and water were mixed at a mass ratio of 1:50 and soaked at 30°C for 40 minutes to obtain a soaking product. Lactobacillus plantarum (Latin: ) was then added to the soaking product. Lactobacillus plantarum, The effective viable count of Lactobacillus plantarum is 1×10⁻⁶. 8 (cfu / g, based on the mass fraction of sorghum, with a mass ratio of sorghum to Lactobacillus plantarum of 1:0.05) were mixed evenly and fermented aerobically at 42℃ for 3 hours to obtain fermentation broth. The fermentation broth was then concentrated and dried at 40℃ to obtain sorghum fermentation product. The extracts of eucalyptus leaves, Uncaria rhynchophylla, Podocarpus macrophyllus, lemon leaves, coconut meat, rose, and sorghum ferment were mixed evenly to obtain a composition.

[0021] Comparative Example 1 The steps for preparing a composition for preventing hair loss and strengthening hair roots are as follows: (1) The composition comprises the following components in parts by weight: 10 parts of eucalyptus leaf extract, 22 parts of coconut meat extract, 18 parts of Uncaria rhynchophylla extract, 10 parts of Podocarpus macrophyllus extract, 5 parts of lemon leaf extract, 5 parts of rose extract and 5 parts of sorghum ferment.

[0022] (2) The preparation process is the same as (2) in Example 1.

[0023] Comparative Example 2 The steps for preparing a composition for preventing hair loss and strengthening hair roots are as follows: (1) Same as (1) in Example 1.

[0024] (2) The preparation process is as follows: The crushed eucalyptus leaves were mixed with a 95% ethanol solution at a mass-volume ratio of 1g:10mL and heated at 95℃ for 35min to obtain an extract. The extract was filtered to obtain a filtrate, which was then concentrated under reduced pressure to recover the solvent and obtain a concentrate. The concentrate was then dried in an oven at 40℃ to obtain the eucalyptus leaf extract. The preparation methods for Uncaria rhynchophylla extract, Podocarpus macrophyllus extract, lemon leaf extract, coconut meat extract, and rose extract are the same as those for the preparation method of Eucalyptus globulus leaf extract. Crushed sorghum and water were mixed at a mass ratio of 1:50 and soaked at 30°C for 40 minutes to obtain a soaking product. Lactobacillus plantarum (Latin: ) was then added to the soaking product. Lactobacillus plantarum, The effective viable count of Lactobacillus plantarum is 1×10⁻⁶. 8 (cfu / g, based on the mass fraction of sorghum, with a mass ratio of sorghum to Lactobacillus plantarum of 1:0.05) were mixed evenly and fermented aerobically at 42℃ for 3 hours to obtain fermentation broth. The fermentation broth was then concentrated and dried at 40℃ to obtain sorghum fermentation product. The extracts of eucalyptus leaves, Uncaria rhynchophylla, Podocarpus macrophyllus, lemon leaves, coconut meat, rose, and sorghum ferment were mixed evenly to obtain a composition.

[0025] Comparative Example 3 The steps for preparing a composition for preventing hair loss and strengthening hair roots are as follows: (1) The composition comprises the following components in parts by weight: 15 parts of eucalyptus leaf extract, 22 parts of coconut meat extract, 8 parts of Uncaria rhynchophylla extract, 10 parts of Podocarpus macrophyllus extract, 20 parts of lemon leaf extract, 5 parts of rose extract and 5 parts of rice water concentrate.

[0026] (2) The preparation process is as follows: The preparation methods for eucalyptus leaf extract, Uncaria rhynchophylla extract, Podocarpus macrophyllus extract, lemon leaf extract, coconut meat extract, and rose extract are the same as those in Example 1. Preparation process of rice water concentrate: Mix rice and water at a mass ratio of 1:10 and soak at 30℃ for 10 hours to obtain a mixture; perform solid-liquid separation on the mixture to obtain a filtrate; concentrate and dry the filtrate at 40℃ to obtain rice water concentrate; Comparative Example 4 The steps for preparing a composition for preventing hair loss and strengthening hair roots are as follows: (1) Same as (1) in Example 1.

[0027] (2) The preparation process is as follows: The crushed eucalyptus leaves were mixed with a 95% ethanol solution at a mass-volume ratio of 1g:10mL and heated at 95℃ for 35min to obtain an extract. The extract was filtered to obtain a filtrate, which was then concentrated under reduced pressure to recover the solvent and obtain a concentrate. The concentrate was then dried in an oven at 40℃ to obtain the eucalyptus leaf extract. The preparation methods for Uncaria rhynchophylla extract, Podocarpus macrophyllus extract, and lemon leaf extract are the same as those for the preparation method of Eucalyptus globulus leaf extract. The crushed coconut meat was mixed with water at a mass-to-volume ratio of 1:20 mL and then extracted by low-temperature ultrasonication at 35℃ and 120Hz for 2 hours to obtain an extract. The extract was then subjected to solid-liquid separation to obtain a filtrate. The filtrate was then vacuum concentrated to 1 / 3 of its original volume at 60℃ and -0.06MPa to obtain the coconut meat extract. The preparation method of rose extract is the same as that of coconut meat extract described above; The crushed sorghum was mixed with water at a mass ratio of 1:50 and soaked at 30°C for 4 hours. Then, solid-liquid separation was performed to obtain the filtrate. The filtrate was concentrated and dried at 40°C to obtain the sorghum fermentation product. The extracts of eucalyptus leaves, Uncaria rhynchophylla, Podocarpus macrophyllus, lemon leaves, coconut meat, rose, and sorghum ferment were mixed evenly to obtain a composition.

[0028] Comparative Example 5 The steps for preparing a composition for preventing hair loss and strengthening hair roots are as follows: (1) Same as (1) in Example 1.

[0029] (2) The preparation process is as follows: The crushed coconut meat was mixed with water at a mass-to-volume ratio of 1:20 mL and then extracted by low-temperature ultrasonication at 35℃ and 120Hz for 2 hours to obtain an extract. The extract was then subjected to solid-liquid separation to obtain a filtrate. The filtrate was then vacuum concentrated to 1 / 3 of its original volume at 60℃ and -0.06MPa to obtain the coconut meat extract. The preparation methods for extracts of Uncaria rhynchophylla, Podocarpus macrophyllus, lemon leaf, and rose are the same as those for the coconut meat extract. Crushed sorghum and water were mixed at a mass ratio of 1:50 and soaked at 30°C for 40 minutes to obtain a soaking product. Lactobacillus plantarum (Latin: ) was then added to the soaking product. Lactobacillus plantarum, The effective viable count of Lactobacillus plantarum is 1×10⁻⁶. 8 (cfu / g, based on the mass fraction of sorghum, with a mass ratio of sorghum to Lactobacillus plantarum of 1:0.05) were mixed evenly and fermented aerobically at 42℃ for 3 hours to obtain fermentation broth. The fermentation broth was then concentrated and dried at 40℃ to obtain sorghum fermentation product. The extracts of eucalyptus leaves, Uncaria rhynchophylla, Podocarpus macrophyllus, lemon leaves, coconut meat, rose, and sorghum ferment were mixed evenly to obtain a composition.

[0030] Application Example 1 The compositions prepared in Example 1 and Comparative Examples 1-5 were dissolved in water to obtain test solutions with a final concentration of 0.5 g / mL. Male Wistar rats were used as experimental subjects. The rats were divided into 7 regions from head to tail along the spine. The fur of each region was cleaned. The 6 regions were labeled as Group 1, Group 2... Group 7. A total of 5 mice were used in the experiment, and each mouse was a replicate. Group 1: Apply 0.5 mL of the test solution from Example 1 daily; Group 2: Apply 0.5 mL of the test solution from Comparative Example 1 daily; Group 3: Apply 0.5 mL of the test solution from Comparative Example 2 daily; Group 4: Apply 0.5 mL of the test solution from Comparative Example 3 daily; Group 5: Apply 0.5 mL of the test solution from Comparative Example 4 daily; Group 6: Apply 0.5 mL of the test solution from Comparative Example 5 daily; Group 7: Apply 0.5mL of water daily; After 30 days of continuous application, a tuft of new hair was plucked from each area of ​​5 mice. The top 10 new hairs in length from each group were selected and their average length was taken as the hair growth length value. All the mouse hair from each group was collected and weighed as the hair growth weight value. In addition, the mice were observed for any abnormal symptoms such as redness, swelling, and itching in the application area. The results are shown in Table 1.

[0031] Table 1. Hair growth in mice under different treatments and appearance of the treated areas.

[0032] As can be seen from the data in Table 1, the composition prepared in Example 1 is beneficial for improving scalp microcirculation, providing more nutrients to hair follicles, and thus enhancing the vitality of hair follicles. Therefore, it has the best effect in maintaining the balance of the hair growth environment and promoting hair growth. Moreover, the composition is green and safe, so there are no abnormal symptoms such as redness, swelling, or itching in the application area.

[0033] Application Example 2 Based on the results of Application Example 1, the compositions prepared in Group 1 (Example 1), Group 2 (Comparative Example 1), and Group 6 (Comparative Example 5) were selected for the following experiments; The raw materials were processed to prepare the hair shampoo as follows: Group A: The shampoo, by mass percentage, comprises: 10% of the composition prepared in Example 1, 5% hexanediol, 3% silicone oil, 6% sodium lauryl ether sulfate, 0.8% cocamide, 0.7% lauroyl hydroxysulfonate betaine, and the balance being water; Group B: The only difference from Group A is that the composition prepared in Comparative Example 1 is used instead of the composition prepared in Example 1; Group C: The only difference from Group A is that the composition prepared in Comparative Example 5 is used instead of the composition prepared in Example 1; We are recruiting female volunteers (aged 25-35) with medium to long hair who have not permed or dyed their hair in the past 3 months and are experiencing hair loss. The volunteers will be randomly divided into 4 groups of 5 people each. Each volunteer will wash their hair once every other day. The washing and conditioning methods and the amount of shampoo used will be maintained according to the volunteers' habits.

[0034] Group 1: Validation using Group A shampoo; Group 2: Validation using Group B hair wash; Group 3: Validation using Group C shampoo; Group 4: Verification using commercially available shampoos; After the first wash and blow-dry, and after the 15th wash and blow-dry, the hair strength was tested using a hair tensile strength tester. Twenty hairs were taken from each volunteer, and the test was conducted on 10cm of the middle section of the hair. The growth rate of hair strength was calculated, and the results are shown in Table 2.

[0035] Hair strength growth rate (%) = (Tensive strength after N days of use - Tensive strength after 1 day of use) / Tensive strength after 1 day of use × 100% Table 2. Growth rate of hair strength under different treatments

[0036] In addition, during the first hair washing and conditioning experiment of the female volunteers, the number of hairs that fell out during the washing process in each group was collected and recorded as the initial hair loss amount, and the average initial hair loss amount of each group was calculated; and during the 15th hair washing and conditioning, the number of hairs that fell out during the washing process was collected and recorded as the final hair loss amount, and the average final hair loss amount was calculated. The results are shown in Table 3.

[0037] Hair loss reduction rate (%) = (Average initial hair loss amount - Average final hair loss amount) / Average initial hair loss amount × 100% Table 3. Hair loss reduction rate under different treatments

[0038] As can be seen from the data in Tables 2 and 3, when volunteers used the hair shampoo provided by this invention, the strength of their hair was significantly improved, and the amount of hair was also effectively controlled.

[0039] In summary, the composition and shampoo for preventing hair loss and strengthening hair roots provided by this invention can regulate the scalp environment and enhance the vitality of hair follicles to achieve the effect of strengthening hair roots; in addition, it enhances the toughness of hair and improves the condition of hair strands that are easy to break, thereby achieving the purpose of preventing hair loss and strengthening hair.

[0040] Although the above embodiments have provided a detailed description of the present invention, they are only some embodiments of the present invention, and not all embodiments. People can obtain other embodiments based on these embodiments without creative effort, and these embodiments all fall within the protection scope of the present invention.

Claims

1. A composition for preventing hair loss and strengthening hair roots, characterized in that, The composition comprises the following components in parts by weight: 15-20 parts of eucalyptus leaf extract, 18-23 parts of coconut meat extract, 6-10 parts of Uncaria rhynchophylla extract, 10-18 parts of Podocarpus macrophyllus extract, 20-25 parts of lemon leaf extract, 3-5 parts of rose extract, and 5-10 parts of sorghum ferment.

2. The composition according to claim 1, characterized in that, The composition comprises the following components in parts by weight: 15 parts of eucalyptus leaf extract, 22 parts of coconut meat extract, 8 parts of Uncaria rhynchophylla extract, 10 parts of Podocarpus macrophyllus extract, 20 parts of lemon leaf extract, 5 parts of rose extract, and 5 parts of sorghum fermentation product.

3. A method for preparing the composition according to claim 1 or 2, characterized in that, Includes the following steps: The leaves of Eucalyptus globulus, Uncaria rhynchophylla, Podocarpus macrophyllus, and lemon leaves were respectively mixed with ethanol solution, heated, concentrated and dried to obtain Eucalyptus globulus leaf extract, Uncaria rhynchophylla extract, Podocarpus macrophyllus extract and lemon leaf extract. Coconut meat and rose were mixed with water and then subjected to low-temperature ultrasonic extraction, solid-liquid separation and vacuum concentration to obtain coconut meat extract and rose extract. After soaking sorghum in water, add Lactobacillus plantarum and carry out aerobic fermentation, solid-liquid separation and low-temperature concentration and drying to obtain sorghum fermentation product; The extracts of eucalyptus leaves, Uncaria rhynchophylla, Podocarpus macrophyllus, lemon leaves, coconut meat, rose, and sorghum fermentation were mixed evenly to obtain a composition.

4. The preparation method according to claim 3, characterized in that, The mass-to-volume ratio of the leaves of the blue gum tree, the ancient vine, the podocarpus, the lemon leaves and the ethanol solution was 1g:10-12mL. The volume concentration of the ethanol solution is 90%-95%.

5. The preparation method according to claim 3, characterized in that, The heating conditions include a temperature of 90-100℃ and a time of 35-45 minutes.

6. The preparation method according to claim 3, characterized in that, The mass-to-volume ratio of coconut meat, rose petals, and water is 1:18-25mL. The conditions for low-temperature ultrasonic extraction include: temperature of 30-35℃, time of 2-3 hours, and power of 100-120Hz.

7. The preparation method according to claim 3, characterized in that, The mass ratio of sorghum, water, and *Lactobacillus plantarum* is 1:40-50:0.05-0.1; The effective viable count of *Lactobacillus plantarum* is ≥0.5 × 10⁻⁶. 7 cfu / g.

8. The preparation method according to claim 3, characterized in that, The conditions for the mixed soaking include: a temperature of 30-35℃ and a time of 30-40 minutes; The conditions for the aerobic fermentation include: a temperature of 42-45℃ and a time of 3-4 hours.

9. The use of the composition of claim 1 or 2 in the preparation of hair loss prevention and / or root strengthening products.

10. A hair shampoo for preventing hair loss and strengthening hair roots, characterized in that, The shampoo comprises the composition according to claim 1 or 2.

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