Anti-hair-loss composition based on Chinese herbal medicine plant extracts and preparation method of anti-hair-loss composition

Abstract

The invention discloses an anti-hair loss composition based on Chinese herbal medicine plant extracts, which comprises the following components: a surfactant system, a Chinese herbal medicine plant extract compound group and a nutrition repair group, the Chinese herbal medicine plant extract compound group comprises a polygonum multiflorum extract, a cacumen biotae extract, a sophora flavescens extract, a ginger root extract, ginger root oil, an angelica sinensis root extract and a soapberry extract, and the nutrition restoration group comprises hydrolyzed wheat protein, sodium hyaluronate, plant amino acids, camellia-seed oil, biological phenol, pantothenic acid, ethylhexylglycerin and the balance of a solvent. The composition has the advantages that the seven Chinese herbal medicine extracts are subjected to water-alcohol double extraction, the hair loss causes are comprehensively covered, and the multiple effects of promoting growth, inhibiting hair loss and controlling oil are achieved; by adopting a process of mixing step by step and adding active matters at low temperature, the damage of high temperature to active ingredients and nutrient substances of the Chinese herbal medicines is effectively avoided.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of washing products, in particular to a hair loss prevention composition based on Chinese herbal medicine plant extract and a preparation method thereof. BACKGROUND

[0002] Existing hair loss prevention products mainly add chemical drugs that can remove oil and stimulate hair follicles. In the short term, they can clean the scalp and stimulate hair follicles to grow, but long-term use will have the opposite effect.

[0003] Plant extract products have become a research hotspot due to their high safety, but existing technologies still have significant defects: Most commercially available products use only one or a few plant extracts, and the synergy between the extracts is insufficient, lacking comprehensive intervention for multiple mechanisms of hair loss.

[0004] In existing technologies, Chinese herbal medicine extracts are simply added to washing and care products, which often have low effective ingredient content, poor solubility and dispersibility, easy inactivation, and incompatibility with surfactant systems, resulting in poor final product performance.

[0005] The information disclosed in this BACKGROUND section is only intended to increase an understanding of the general context of the application and is not to be taken in any way as an acknowledgment or any form of suggestion that this information forms the prior art that is already known to those of ordinary skill in the art. SUMMARY

[0006] The present application aims to overcome the above-mentioned defects and provide a hair loss prevention composition based on Chinese herbal medicine plant extract and a preparation method thereof.

[0007] To solve the above-mentioned technical problems, the present application provides a hair loss prevention composition based on Chinese herbal medicine plant extract, which comprises the following components in terms of weight percentage: a surfactant system, a Chinese herbal medicine plant extract composite group, and a nutrition repair group; The surfactant system accounts for 10-30% and contains anionic surfactants and zwitterionic surfactants. The Chinese herbal medicine plant extract composite group accounts for 1-15% and contains radix polygoni multiflori extract, cypress leaf extract, sophora flavescens extract, ginger root extract, ginger root oil, angelica sinensis root extract, and soapberry extract, all of which are obtained by water-alcohol double extraction. The nutrition repair group accounts for 0.1-8% and contains hydrolyzed wheat protein, sodium hyaluronate, plant amino acids, camellia seed oil, biological phenol, pantothenic acid, and ethylhexylglycerin. It also includes a solvent in an amount.

[0008] The application further preferably relates to the anionic surfactant being at least one of sodium methyl cocoyl taurate and decyl glucoside.

[0009] The application further preferably relates to the zwitterionic surfactant being cocamidopropyl betaine.

[0010] The application further preferably relates to the active solid content of the water-alcohol double-extracted Chinese herbal medicine extract being greater than or equal to 20%.

[0011] The application further preferably relates to the Radix Angelicae Sinensis extract 0.1-3%, the Platycladus orientalis extract 0.1-3%, the Sophora flavescens extract 0.1-2%, the Zingiber officinale extract 0.1-2%, the Zingiber officinale oil 0.05-1%, the Radix Angelicae Sinensis extract 0.1-2%, and the Sapindus extract 0.5-4%.

[0012] The application further preferably relates to the hydrolyzed wheat protein 0.1-2%, the sodium hyaluronate 0.05-1%, the plant amino acid 0.1-1.5%, the Camellia seed oil 0.1-2%, the biological phenol 0.01-0.5%, the pantothenic acid 0.01-0.3%, and the ethylhexylglycerin 0.1-0.5%.

[0013] The application further preferably relates to the solvent being one or more of water, ethanol, glycerol, and propylene glycol.

[0014] The preparation method is as follows: S1, mixing and stirring each component of the surfactant system with part of the solvent at 70-80°C until completely dissolved to obtain a uniform and transparent base A; S2, cooling the obtained base A to below 45°C; S3, mixing each component in the Chinese herbal medicine plant extract composite group with part of the solvent at room temperature to obtain a mixture B; S4, mixing each component in the nutrition repair group with part of the solvent at room temperature to obtain a mixture C; S5, under the state of stirring, sequentially adding the mixture B and the mixture C into the cooled base A, and continuously stirring until the system is uniform; S6, adjusting the pH value of the system to 5.5-6.5, and supplementing the remaining solvent to 100%, and then stirring uniformly to obtain the anti-hair loss composition.

[0015] The application further preferably relates to the pH adjuster being used to adjust the pH value of the system in step S6.

[0016] The application further preferably relates to the pH adjuster being one or more of citric acid, lactic acid, sodium hydroxide, and triethanolamine.

[0017] Compared with the prior art, the present application has the following advantages, including but not limited to: Seven Chinese herbal medicine extracts are extracted by water-alcohol double extraction, which comprehensively covers the causes of hair loss: Radix Angelicae Sinensis and Radix Polygoni Multiflori activate hair follicle stem cells, Platycladus orientalis and Sophora flavescens inhibit 5α-reductase, ginger root oil and Sapindus saponin control oil and inhibit bacteria, realizing the triple action of "promoting growth-inhibiting loss-controlling oil".

[0018] The preparation method adopts a process of step-by-step mixing and low-temperature addition of active substances, which effectively avoids the damage of high temperature to the active ingredients and nutrients of Chinese herbal medicines, and ensures the stability of the efficacy of the final product. DETAILED DESCRIPTION

[0019] The implementations described in the following exemplary embodiments do not represent all implementations consistent with the present disclosure. Instead, they are merely examples of apparatuses consistent with some aspects of the present disclosure as detailed in the appended claims.

[0020] First embodiment: The present embodiment discloses a hair loss prevention composition based on Chinese herbal medicine plant extract and a preparation method thereof. In this embodiment, the hair loss prevention composition based on Chinese herbal medicine plant extract comprises: A surfactant system, a Chinese herbal medicine plant extract composite group, a nutrient repair group, and a solvent.

[0021] Specifically, the surfactant system accounts for 10-30%, including anionic surfactants and zwitterionic surfactants. Further, the anionic surfactant is at least one of sodium methyl cocoyl taurate and decyl glucoside, and in this embodiment, both sodium methyl cocoyl taurate and decyl glucoside are selected.

[0022] The Chinese herbal medicine plant extract composite group accounts for 1-15%, and the components and contents are as follows: Radix Polygoni Multiflori extract 0.1-3%, Platycladus orientalis extract 0.1-3%, Sophora flavescens extract 0.1-2%, ginger root extract 0.1-2%, ginger root oil 0.05-1%, Radix Angelicae Sinensis extract 0.1-2%, and Sapindus saponin extract 0.5-4%.

[0023] It is explained that the extracts are obtained by water-alcohol double extraction, and the active solid content is determined by refractometry / drying method. Moreover, in the Chinese herbal medicine extract obtained by water-alcohol double extraction, the active solid content is ≥20%.

[0024] The nutritional repair group accounts for 0.1-8%, and the ingredients and contents are as follows: hydrolyzed wheat protein 0.1-2%, sodium hyaluronate 0.05-1%, plant amino acids 0.1-1.5%, camellia seed oil 0.1-2%, bio-phenol 0.01-0.5%, pantothenic acid 0.01-0.3%, and ethylhexylglycerin 0.1-0.5%.

[0025] The balance is water, and the solvent is one or more of water, ethanol, glycerol, and propylene glycol. In this embodiment, water and glycerol are selected as solvents.

[0026] Second embodiment: Preparation method: Step one: add part of deionized water to the reaction pot, heat to 75°C, add methyl sodium cocoyl taurate, decyl glucoside, and cocamidopropyl betaine, and stir at a uniform speed until completely dissolved to form a uniform transparent base A.

[0027] Step two: after obtaining product base A, stop heating and naturally cool the base A to 40°C in the room.

[0028] Step three: in a second container, mix the extract of radix polygoni multiflori, leaf of biota orientalis, radix sophorae flavescentis, radix paeoniae alba, radix angelicae sinensis, and semen aesculi, and ginger root oil with part of deionized water at room temperature, and stir uniformly to obtain mixture B.

[0029] Step four: in a third container, mix hydrolyzed wheat protein, sodium hyaluronate, plant amino acids, camellia seed oil, vitamin E, pantothenic acid, and ethylhexylglycerin with part of deionized water at room temperature, and stir uniformly to obtain mixture C.

[0030] Step five: under low-speed stirring, slowly add mixture B and mixture C to the cooled base A in sequence, increase the stirring speed after adding, and stir for 30 minutes until the system is completely uniform.

[0031] Step six: adjust the pH value of the system to 6.0 with a small amount of aqueous citric acid solution, supplement the remaining deionized water to 100%, and continue stirring for 20 minutes.

[0032] Step seven: discharge, stand for defoaming, fill, and obtain the final product.

[0033] Third embodiment: Comparative example 1: common anti-hair loss shampoo formula on the market Formula: sodium laureth sulfate 12%, cocamidopropyl betaine 7%, sodium chloride 1%, ginger extract 2%, leaf of biota orientalis extract 1%, silicone oil 3%, preservative 0.2%, fragrance 0.2%, and deionized water balance.

[0034] Preparation method: all components are mixed and stirred at 75°C, and then cooled and adjusted to pH 6.0.

[0035] Comparative Example 2: Comparative composition with missing key Chinese herbal components Formulation ingredients: Sodium methyl cocoyl taurate 10%, decyl glucoside 5%, cocamidopropyl betaine 8%, hydrolyzed wheat protein 0.5%, sodium hyaluronate 0.1%, plant amino acids 0.5%, camellia seed oil 0.8%, bio-phenol (vitamin E) 0.1%, pantothenic acid 0.1%, ethylhexylglycerin 0.3%, glycerin 5%, deionized water to 100%.

[0036] Preparation method: Step one, add part of deionized water to the reaction pot, heat to 75°C, add sodium methyl cocoyl taurate, decyl glucoside, and cocamidopropyl betaine, and stir evenly until completely dissolved to form a uniform transparent base A.

[0037] Step two, after obtaining product base A, stop heating and allow base A to cool naturally to 40°C indoors.

[0038] Step three, in a second container, mix Platycladus orientalis, ginger root, soapberry extract, and ginger root oil with part of deionized water at room temperature, and stir until uniform to obtain mixture B.

[0039] Step four, in a third container, mix hydrolyzed wheat protein, sodium hyaluronate, plant amino acids, camellia seed oil, vitamin E, pantothenic acid, and ethylhexylglycerin with part of deionized water at room temperature, and stir until uniform to obtain mixture C.

[0040] Step five, under low-speed stirring, slowly add mixture B and mixture C to the cooled base A in sequence, and after adding, increase the stirring speed and stir for 30 minutes until the system is completely uniform.

[0041] Step six, adjust the pH value of the system to 6.0 with a small amount of aqueous citric acid solution, and supplement the remaining deionized water to 100%, and continue stirring for 20 minutes.

[0042] Step seven, discharge, stand for defoaming, and then fill to obtain the final product of Comparative Example 2.

[0043] Comparative Example 3: Comparison of high-temperature active material addition process Formulation ingredients: Sodium methyl cocoyl taurate 10%, decyl glucoside 5%, cocamidopropyl betaine 8%, radix angelicae sinensis extract 1%, Platycladus orientalis extract 1.5%, sophora flavescens extract 1%, ginger root extract 0.8%, ginger root oil 0.3%, radix angelicae sinensis extract 1%, soapberry extract 2%; nutrient repair group contains hydrolyzed wheat protein 0.5%, sodium hyaluronate 0.1%, plant amino acids 0.5%, camellia seed oil 0.8%, bio-phenol 0.1%, pantothenic acid 0.1%, ethylhexylglycerin 0.3%; solvent is glycerin 5% and the balance of deionized water.

[0044] Preparation method: step one, add part of deionized water into the reaction pot, heat to 75°C, add sodium methyl cocoyl taurate, decyl glucoside, cocamidopropyl betaine, stir evenly until completely dissolved, form uniform transparent base A.

[0045] Step two, in the second container, mix Platycladus orientalis, ginger root, soapberry extract and ginger root oil with part of deionized water at room temperature, stir evenly, get mixture B.

[0046] Step three, in the third container, mix hydrolyzed wheat protein, sodium hyaluronate, plant amino acid, camellia seed oil, vitamin E, pantothenic acid, ethylhexylglycerin with part of deionized water at room temperature, stir evenly, get mixture C.

[0047] Step four, under low speed stirring, slowly add mixture B and mixture C into base A in turn, after adding, increase stirring speed, stir for 30 minutes until the system is completely uniform.

[0048] Step five, adjust the pH value of the system to 6.0 with a small amount of aqueous citric acid solution, supplement the remaining deionized water to 100%, continue stirring for 20 minutes.

[0049] Step six, discharge, stand for defoaming, then fill, get the final product of comparative example 2.

[0050] Fourth embodiment: Human trial test: select 32 cases of healthy female volunteers aged 30 to 45 with mild to moderate alopecia symptoms, divide them into 4 groups by random grouping method, 8 cases in each group. Before the test, draw a 1.0 cm x 1.0 cm observation area on the occipital scalp of each subject, and use professional hair cutting tools to remove the hair in the area.

[0051] Each group uses the shampoo products prepared in the first to second embodiments and comparative examples 1-3. The use method is as follows: after wetting the hair, take 5 g of product and rub it to foam, evenly apply it to the scalp and hair, use the palm to massage from the root to the tip in a ring shape, gently clean for 3-5 minutes, then rinse thoroughly with warm water (37±1°C). Use once every 2 days, for 8 weeks continuously. During the test period, the subjects are required not to use any other scalp care cosmetics, hair growth drugs or health care products.

[0052] After the use is finished, the newly grown hair in the observation area is shaved and weighed using a precision electronic balance (accurate to 0.1 mg), and 10 hair samples are randomly selected to measure the length, taking the arithmetic mean, the data is recorded in Table 1. At the same time, at the beginning and end of the test, the number of hair loss during morning combing for 3 consecutive days is counted, the average value and the change rate in the group are calculated, the results are shown in Table 2.

[0053] Table 1 average hair length and hair weight From the above table 1, it can be seen that the shampoo prepared by the first and second embodiments of the present application can effectively promote hair growth, and make the hair become thick and long, and the effect is better than that of the shampoo prepared by the comparative examples 1-3.

[0054] Table 2 change in the number of hair loss (root) From the above table 2, it can be seen that the shampoo prepared by the first and second embodiments of the present application can effectively alleviate the symptoms of hair loss, and has the effect of preventing and treating hair loss, and the effect is better than that of the shampoo prepared by the comparative examples 1-3.

[0055] The above describes the present application and its embodiments, which is not limited. In general, if a person skilled in the art is inspired by it, without departing from the purpose of the present application, without creative design, similar structural ways and embodiments of the technical solutions should belong to the protection scope of the present application.

[0056] The detailed description of known functions and known components is omitted in the specific embodiments of the present disclosure, and the operation means adopted is consistent with the parameters of the market equipment to ensure the compatibility of the equipment.

Claims

1. A hair loss prevention composition based on extracts from traditional Chinese herbal plants, characterized in that, By weight percentage, it includes the following components: Surfactant system, compound group of Chinese herbal plant extracts and nutritional repair group; The surfactant system accounts for 10-30%, including anionic surfactants and amphoteric surfactants; The proportion of herbal plant extracts in the compound group is 1-15%, including Polygonum multiflorum extract, Platycladus orientalis leaf extract, Sophora flavescens extract, ginger root extract, ginger root oil, Angelica sinensis root extract and Sapindus mukorossi extract, all of which are obtained by water-alcohol double extraction. The nutritional repair group accounts for 0.1-8% and includes hydrolyzed wheat protein, sodium hyaluronate, plant amino acids, camellia seed oil, biophenol, pantothenic acid and ethylhexylglycerin; It also includes the remaining solvent.

2. The anti-hair loss composition based on traditional Chinese herbal plant extracts according to claim 1, characterized in that: The anionic surfactant is at least one of sodium methylcocoyl taurate and decyl glucoside.

3. The anti-hair loss composition based on traditional Chinese herbal plant extracts according to claim 1, characterized in that: The zwitterionic surfactant is cocamidopropyl betaine.

4. The anti-hair loss composition based on traditional Chinese herbal plant extracts according to claim 1, characterized in that: The active solids content in the herbal extract obtained by water-alcohol dual extraction is ≥20%.

5. The anti-hair loss composition based on traditional Chinese herbal plant extracts according to claim 1, characterized in that: The extracts contained in the following ingredients were: Polygonum multiflorum extract 0.1-3%, Platycladus orientalis leaf extract 0.1-3%, Sophora flavescens extract 0.1-2%, Zingiber officinale root extract 0.1-2%, Zingiber officinale root oil 0.05-1%, Angelica sinensis root extract 0.1-2%, and Sapindus mukorossi extract 0.5-4%.

6. The anti-hair loss composition based on traditional Chinese herbal plant extracts according to claim 1, characterized in that: Hydrolyzed wheat protein 0.1-2%, sodium hyaluronate 0.05-1%, plant amino acids 0.1-1.5%, camellia seed oil 0.1-2%, biophenols 0.01-0.5%, pantothenic acid 0.01-0.3%, ethylhexylglycerin 0.1-0.5%.

7. The anti-hair loss composition based on traditional Chinese herbal plant extracts according to claim 1, characterized in that: The solvent is one or more of water, ethanol, glycerol, and propylene glycol.

8. A method for preparing a hair loss prevention composition based on traditional Chinese herbal plant extracts according to any one of claims 1 to 7, characterized in that: S1. Mix and stir each component of the surfactant system with a portion of the solvent at 70-80°C until completely dissolved to obtain a uniform and transparent base material A; S2. Cool the obtained base material A to below 45°C; S3. Mix each component of the herbal plant extract complex with a portion of the solvent at room temperature to obtain mixture B; S4. Mix each component in the nutrient repair group with a portion of the solvent at room temperature to obtain mixture C; S5. While stirring, add mixture B and mixture C to the cooled base material A in sequence, and continue stirring until the system is homogeneous; S6. Adjust the pH of the system to 5.5-6.5, and add the remaining solvent to 100%. Stir well to obtain the hair loss prevention composition.

9. A method for preparing an anti-hair loss composition according to claim 8, characterized in that: In step S6, a pH adjuster is used to adjust the pH value of the system.

10. A method for preparing an anti-hair loss composition according to claim 9, characterized in that... The pH adjuster is one or more of citric acid, lactic acid, sodium hydroxide, and triethanolamine.

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