Traditional Chinese medicine composition for improving kidney-yang deficiency and resisting fatigue and application thereof

Abstract

The invention discloses a traditional Chinese medicine composition for improving kidney-yang deficiency and resisting fatigue. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 10-50 parts of cordyceps sinensis, 10-50 parts of hairy antler, 10-50 parts of ginseng, 10-50 parts of dendrobium officinale and 10-50 parts of glossy privet fruit. According to the present invention, the idea of treatment based on syndrome differentiation of traditional Chinese medicine is adopted, the daily fatigue symptom of contemporary people is combined with the consumptive disease of traditional Chinese medicine, the traditional Chinese medicine formula of monarch, minister, assistant and guide is adopted, and the good treatment and improvement effect is provided for the comprehensive fatigue problem caused by kidney qi deficiency and kidney yang deficiency.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of traditional Chinese medicine composition preparation, in particular to a traditional Chinese medicine composition for improving kidney yang deficiency and resisting fatigue, and application thereof in the field of health food or medicine. BACKGROUND

[0002] In today's society, high-intensity social competition and fast-paced lifestyle, combined with long-term environmental pollution and unhealthy lifestyle factors, are prone to cause "fatigue" and other "sub-health" problems, and if left unattended for a long time, it may cause endocrine disorders and organic lesions, endangering health.

[0003] With the improvement of living standards and the improvement of health consciousness, more and more people start to take health food to cope with various "sub-health" problems in daily life. However, the existing health food functions are mainly aimed at physical fatigue caused by exercise, high-intensity labor, overtime and shift work. Fatigue is a complex physiological state, including physical fatigue, mental fatigue, psychological fatigue and mixed fatigue. Modern people's fatigue problems cannot be simply attributed to a single factor, both energy material decline caused by physical and mental labor, and metabolic disorders caused by psychological stress, so most anti-fatigue health foods cannot effectively solve the comprehensive fatigue problems of modern people.

[0004] Most traditional Chinese medicines for treating kidney yang deficiency use symptomatic treatment, and few consider overall conditioning. Long-term use can easily cause yin and yang imbalance and induce adverse reactions such as heat. The traditional Chinese medicine composition of the present application balances yin and yang and consolidates the foundation and essence, and solves the side effects caused by long-term use of traditional Chinese medicine through health food related function verification, which can meet the daily health care needs of modern people.

[0005] In summary, it is urgent to use traditional Chinese medicine theory to diagnose and treat the symptoms of modern people's deficiency fatigue, adopt the form of traditional Chinese medicine composition, and develop and design a traditional Chinese medicine health care product suitable for daily use to solve the problems of long-term use of most tonic products, lack of significant efficacy, and other problems caused by kidney yang deficiency and fatigue syndrome. SUMMARY

[0006] The present application provides a traditional Chinese medicine composition for improving kidney yang deficiency and resisting fatigue and its application. The present application combines the daily fatigue symptoms of modern people with the traditional Chinese medicine "asthenia" syndrome, uses the traditional Chinese medicine diagnosis and treatment theory, adopts the traditional Chinese medicine prescription of monarch, minister, assistant and messenger, and has good therapeutic effect on the comprehensive fatigue caused by kidney qi deficiency and kidney yang deficiency.

[0007] As one of the purposes of the present application, the present application provides a traditional Chinese medicine composition for improving kidney yang deficiency and anti-fatigue, which is composed of the following raw materials in parts by weight: Cordyceps sinensis 10-50 parts, Cervus elaphus 10-50 parts, Panax ginseng 10-50 parts, Dendrobium officinale 10-50 parts, and Ligustrum lucidum 10-50 parts.

[0008] Cordyceps sinensis is the dry complex of the stroma of Cordyceps sinensis (BerK.) Sacc. parasitizing on the larvae of Hepialidae and the larvae corpses. It is neutral in nature and sweet in taste. It belongs to the lung and kidney channels. It has the effects of tonifying the kidney and lung, stopping bleeding and reducing phlegm. It is used for kidney deficiency and essence deficiency, impotence and spermatorrhea, soreness and pain in the waist and knees, chronic cough and shortness of breath, and labor cough and hemoptysis.

[0009] Cervus elaphus is the unossified dense moles of the young horns of Cervus elaphus Linnaeus. It is warm in nature and sweet and salty in taste. It belongs to the kidney and liver channels. It strengthens the kidney yang, benefits essence and blood, strengthens the tendons and bones, regulates the chong and ren, and supports sores and toxins. It is used for kidney yang deficiency, essence and blood deficiency, impotence and spermatorrhea, cold and unfruitful uterus, emaciation, fatigue, dizziness, tinnitus, deafness, cold pain in the waist and back, flaccid tendons and bones, metrorrhagia, leukorrhagia, and non-converging sores.

[0010] Panax ginseng is the dried root and rhizome of Panax ginseng C.A.Mey. of the Araliaceae family. It is slightly warm in nature and sweet and slightly bitter in taste. It belongs to the spleen, lung, and heart channels. It greatly supplements the primordial qi, restores the pulse, supplements the spleen and lung, calms the mind and intelligence, and is used for body weakness, cold limbs, pulse weakness, spleen deficiency, lung deficiency, shortness of breath, dry mouth, internal heat, and deficiency of qi and blood, chronic disease, restlessness, insomnia, impotence, and cold uterus.

[0011] Dendrobium officinale is the dried stem of Dendrobium officinale Kimura et Migo of the Orchidaceae family. It is slightly cold in nature and sweet in taste. It belongs to the stomach and kidney channels. It benefits the stomach, generates saliva, and nourishes yin and clears heat. It is used for heat disease, dry mouth, stomach yin deficiency, dry heaving, post-disease heat, yin deficiency and heat, bone heat, dim eyes, and flaccid tendons and bones.

[0012] Ligustrum lucidum is the dried mature fruit of Ligustrum lucidum Ait. of the Oleaceae family. It is cool in nature and sweet and bitter in taste. It belongs to the liver and kidney channels. It nourishes the liver and kidney, brightens the eyes, and darkens the hair. It is used for liver and kidney yin deficiency, dizziness and tinnitus, soreness and weakness of the waist and knees, early graying of the hair, dim eyes, internal heat, and bone heat.

[0013] Preferably, it is composed of the following raw materials in parts by weight: Cordyceps sinensis 15-30 parts, Cervus elaphus 15-30 parts, Panax ginseng 20-40 parts, Dendrobium officinale 20-40 parts, and Ligustrum lucidum 20-40 parts.

[0014] As one of the purposes of the present application, the present application provides a preparation method of the above-mentioned traditional Chinese medicine composition, comprising the following steps:

[0015] Step 1: powdering or slicing Cordyceps sinensis, Cervus elaphus Linnaeus, Panax ginseng, Dendrobium officinale and Ligustrum lucidum;

[0016] Step 2: adding the raw materials treated in step 1 into water or ethanol for reflux extraction, and preparing a traditional Chinese medicine extract through filtering, concentrating and drying processes;

[0017] Step 3: adding the extract prepared in step 2 into food or medicine and adding auxiliary materials that can be added, and processing and preparing into a required dosage form according to a general preparation process.

[0018] Preferably, the dosage form prepared from the traditional Chinese medicine composition includes but is not limited to tablets, capsules, granules, oral liquids, pills, syrup and any oral dosage form.

[0019] As one of the purposes of the present application, the present application provides an application of the above-mentioned traditional Chinese medicine composition in preparing health food or medicine for improving kidney yang deficiency and resisting fatigue.

[0020] Preferably, the addition amount of the traditional Chinese medicine composition in the health food or medicine is 30%-90%.

[0021] Compared with the prior art, the present application has the following beneficial effects:

[0022] (1) In the traditional Chinese medicine composition provided by the present application, Cordyceps sinensis can supplement lung qi and kidney qi, and is combined with Panax ginseng to strengthen body qi, invigorate life fire and benefit essence; and is combined with Cervus elaphus Linnaeus to invigorate kidney yang and benefit essence, thereby achieving the effects of invigorating yang, tonifying kidney, benefiting essence and filling marrow. Panax ginseng and Cervus elaphus Linnaeus are sweet and warm in nature, and are combined with Ligustrum lucidum and Dendrobium officinale which are cold in nature, which can prevent the medicine from being too warm and dry, and can also make kidney qi and kidney yang be generated from yin essence, thereby helping to balance yin and yang, consolidate the foundation and cultivate the primordial qi. While improving the symptoms of yang deficiency and supplementing kidney qi, the occurrence of uncomfortable symptoms can also be reduced, and the excessive burden of tonifying drugs can be reduced.

[0023] (2) According to the theory of “kidney as the foundation of primordial qi” in traditional Chinese medicine, the present application has obvious improvement effects on the symptoms of kidney essence deficiency and kidney deficiency, such as soreness and weakness of waist and knees, fatigue and easy tiredness, aversion to cold and cold limbs, susceptibility to cold, frequent urination at night, shortness of breath when moving, and mental debilitation, and has no obvious influence on the blood, urine and stool biochemical indexes of the test personnel, and has no obvious influence on the health of the test personnel. In addition, no adverse reactions such as hyperactivity and gastrointestinal discomfort occur after taking the medicine, and therefore the medicine can be used as a daily health tonic.

[0024] (3) The animal experiment verifies that the traditional Chinese medicine composition can significantly prolong the weight-bearing swimming time of mice, reduce the content of serum urea nitrogen and blood lactic acid of mice, and significantly increase the content of liver glycogen. It meets the requirements of relevant procedures of health food function test, and is determined to have the health care effect of anti-fatigue. DETAILED DESCRIPTION

[0025] The following examples are used to illustrate the present application, but are not intended to limit the scope of the present application. If a specific technique or condition is not specified in the examples, it is performed according to the technique or condition described in the literature in the art or according to the product manual. If the manufacturer of the raw material is not specified, it is a conventional product that can be purchased through a regular channel.

[0026] Example 1

[0027] The present embodiment provides a traditional Chinese medicine composition for improving kidney yang deficiency and anti-fatigue, and the specific preparation steps are as follows:

[0028] Dry Cordyceps sinensis in an oven, control the temperature not to exceed 60℃, control the moisture not to exceed 5%, and use a pulverizer to pulverize the dried Cordyceps sinensis into fine powder of 100 mesh or more.

[0029] Further ultrafine grind the Cordyceps sinensis powder to micro powder of 1000 mesh or more.

[0030] Cut deer antler into slices, dry in an oven, control the temperature not to exceed 60℃, control the moisture not to exceed 5%, and use a pulverizer to pulverize the dried deer antler into fine powder of 100 mesh or more.

[0031] Further ultrafine grind the deer antler powder to micro powder of 1000 mesh or more.

[0032] Add 50% concentration ethanol to Panax ginseng, Dendrobium officinale, and Ligustrum lucidum, and reflux extract for 120 minutes. Centrifugal filter the extract, concentrate under reduced pressure, dry and pulverize through an 80 mesh sieve to obtain.

[0033] Mix the traditional Chinese medicine powder and the traditional Chinese medicine extract treated by the above process according to the proportion of 100g of Cordyceps sinensis, 100g of deer antler, 200g of Panax ginseng, 200g of Dendrobium officinale, and 200g of Ligustrum lucidum, add pharmaceutical preparation accessories, and mix, granulate, dry, and press into tablets through the processes of mixing, granulating, drying, and tablet pressing.

[0034] Example 2

[0035] The present embodiment provides a traditional Chinese medicine composition for improving kidney yang deficiency and anti-fatigue, and the specific preparation steps are as follows:

[0036] Dry Cordyceps sinensis in an oven, control the temperature not to exceed 80℃, control the moisture not to exceed 5%, and use a pulverizer to pulverize the dried Cordyceps sinensis into fine powder of 100 mesh or more.

[0037] The Cordyceps sinensis powder is further micronized to a powder of 500 mesh or more.

[0038] The pilose antler is cut into pieces and dried in an oven at a temperature not exceeding 80°C, with the moisture content controlled to be not more than 5%, and the dried pilose antler is ground into a fine powder of 100 mesh or more using a grinder.

[0039] The pilose antler powder is further micronized to a powder of 1500 mesh or more.

[0040] The ginseng, Dendrobium officinale, and Ligustri lucidi Fructus are added to water and boiled to extract for 90 minutes. The extract is centrifuged and filtered, concentrated under reduced pressure, and dried and ground to pass through a 60-mesh sieve to obtain.

[0041] The traditional Chinese medicine powder and the traditional Chinese medicine extract processed by the above process are mixed according to the proportions of 150g of Cordyceps sinensis, 100g of pilose antler, 200g of ginseng, 200g of Dendrobium officinale, and 200g of Ligustri lucidi Fructus, and medicinal preparation accessories are added, and the mixture is granulated, dried, and encapsulated to obtain a capsule.

[0042] Example 3

[0043] The present embodiment provides a traditional Chinese medicine composition for improving kidney yang deficiency and resisting fatigue, and the specific preparation steps are as follows:

[0044] The Cordyceps sinensis is dried in an oven at a temperature not exceeding 80°C, with the moisture content controlled to be not more than 5%, and the dried Cordyceps sinensis is ground into a fine powder of 100 mesh or more using a grinder.

[0045] The Cordyceps sinensis powder is further micronized to a powder of 1500 mesh or more.

[0046] The pilose antler is cut into pieces and dried in an oven at a temperature not exceeding 80°C, with the moisture content controlled to be not more than 5%, and the dried pilose antler is ground into a fine powder of 100 mesh or more using a grinder.

[0047] The pilose antler powder is further micronized to a powder of 1500 mesh or more.

[0048] The Cordyceps sinensis and pilose antler powders are added to water at 50°C and soaked and extracted for 120 minutes, and the filtered medicinal materials are further extracted with water, and this operation is repeated three times.

[0049] The Cordyceps sinensis and pilose antler extract filtrates are separated by membrane filtration.

[0050] The ginseng, Dendrobium officinale, and Ligustri lucidi Fructus are added to water and boiled to extract for 120 minutes. The extract is separated by membrane filtration.

[0051] The above membrane filtrates are combined and concentrated to a relative density of 1.05-1.10 (g / ml).

[0052] The concentrated liquid obtained by the above process is mixed with Cordyceps sinensis 100 g, deer antler 100 g, ginseng 100 g, Dendrobium officinale 200 g, and Ligustrum lucidum 200 g in a ratio of 100:100:100:200:200, with or without the addition of sweeteners, stabilizers, and other liquid preparation adjuvants, and then subjected to mixing, filtration, filling, sterilization, and other processes to produce an oral liquid.

[0053] Example 4

[0054] The present embodiment provides a traditional Chinese medicine composition for improving kidney yang deficiency and resisting fatigue, and the specific preparation steps are as follows:

[0055] Cordyceps sinensis is dried in an oven at a temperature not exceeding 80℃, with the moisture content controlled to be not more than 5%, and the dried Cordyceps sinensis is ground into fine powder of 100 mesh or more using a grinder.

[0056] The Cordyceps sinensis powder is further micronized to micro-powder of 1000 mesh or more.

[0057] Deer antler is cut into pieces and dried in an oven at a temperature not exceeding 80℃, with the moisture content controlled to be not more than 5%, and the dried deer antler is ground into fine powder of 100 mesh or more using a grinder.

[0058] The deer antler powder is further micronized to micro-powder of 1000 mesh or more.

[0059] Cordyceps sinensis, deer antler, ginseng, Dendrobium officinale, and Ligustrum lucidum are added with 50% concentration ethanol for reflux extraction for 120 min. The extract is centrifuged and filtered, concentrated under reduced pressure, dried, and ground through an 80-mesh sieve to obtain the extract.

[0060] The traditional Chinese medicine extract obtained by the above process is mixed with Cordyceps sinensis 150 g, deer antler 150 g, ginseng 200 g, Dendrobium officinale 200 g, and Ligustrum lucidum 200 g in a ratio of 150:150:200:200:200, and pharmaceutical preparation adjuvants are added, followed by mixing, granulation, drying, whole-grain processing, filling, and other processes to produce granules.

[0061] Example 5

[0062] The present embodiment provides a traditional Chinese medicine composition for improving kidney yang deficiency and resisting fatigue, and the specific preparation steps are as follows:

[0063] Cordyceps sinensis is dried in an oven at a temperature not exceeding 100℃, with the moisture content controlled to be not more than 5%, and the dried Cordyceps sinensis is ground into fine powder of 100 mesh or more using a grinder.

[0064] The Cordyceps sinensis powder is further micronized to micro-powder of 800 mesh or more.

[0065] The pilose antler is cut into pieces and dried in an oven at a temperature not exceeding 100°C, the moisture content being controlled to be not more than 5%, and the dried pilose antler is ground into fine powder of 100 mesh or more by using a grinder.

[0066] The pilose antler powder is further micronized into micro powder of 800 mesh or more.

[0067] The cordyceps sinensis and the pilose antler micro powder are soaked in 50°C water for 120 minutes, and the extracted medicine is filtered and the water is added again for extraction, and the operation is repeated for 3 times.

[0068] The cordyceps sinensis and the pilose antler extraction filtrate is separated by membrane filtration.

[0069] The ginseng, the dendrobium officinale, and the ligustrum lucidum are added with water for boiling extraction for 120 minutes, and the extraction filtrate is separated by membrane filtration.

[0070] The membrane filtration filtrates are combined and concentrated to a relative density of 1.25-1.30 (g / ml).

[0071] The traditional Chinese medicine extract treated by the above process is mixed according to the proportion of 200g of cordyceps sinensis, 200g of pilose antler, 200g of ginseng, 300g of dendrobium officinale, and 300g of ligustrum lucidum, and medicinal preparation accessories are added, and the mixture is prepared into soft material, rolled into a round shape, and pressed into a pill.

[0072] Comparative Example 1

[0073] Similar to Example 1, except that the dendrobium officinale is not added, and the rest of the raw materials and parameters are the same as those of Example 1.

[0074] Comparative Example 2

[0075] Similar to Example 1, except that the ligustrum lucidum is not added, and the rest of the raw materials and parameters are the same as those of Example 1.

[0076] Comparative Example 3

[0077] Similar to Example 1, except that the dendrobium officinale and the ligustrum lucidum are not added, and the rest of the raw materials and parameters are the same as those of Example 1.

[0078] Test Example 1 for Improving Kidney Yang Deficiency

[0079] According to the "Guiding Principles for Clinical Research of New Drugs of Traditional Chinese Medicine", 120 male patients aged 18-65 years old who meet the diagnostic criteria for kidney yang deficiency are selected and randomly divided into a product group and a control group according to age.

[0080] Observation index: blood, urine, stool routine, liver and kidney function, adverse reactions. Kidney yang deficiency symptoms (weakness of waist and knees, easy fatigue, cold limbs, mental fatigue, frequent urination at night, shortness of breath, easy to catch a cold) were statistically scored before and after the test according to the severity of the symptoms (severe 3 points, moderate 2 points, mild 1 point), and the main symptoms were improved (1 point for each symptom improvement, 2 points for significant effect), and the symptom improvement rate was calculated.

[0081] Therapeutic effect:

[0082] Significant improvement: symptom score reduction ≥ 70%.

[0083] Improvement: symptom score reduction ≥ 40%.

[0084] No improvement: symptom score reduction < 40%.

[0085] Table 1 Age of subjects

[0086]

[0087] Table 2 Physical examination of subjects

[0088]

[0089] Table 3 Change in symptom score of subjects

[0090]

[0091] Table 4 Efficacy of subjects before and after

[0092]

[0093] The blood, urine, stool routine, liver and kidney function indicators of the subjects before and after the test were within the normal range, and had no significant effect on the health of the subjects.

[0094] Comparison of prescription optimization

[0095] Winter worm and summer grass tonifying kidney and essence, combined with deer antler to strengthen kidney yang and essence and blood, can greatly supplement kidney yang qi, supplemented by ginseng to benefit qi, which can promote the movement of yang qi and spread throughout the body. It is the main material for improving kidney yang deficiency and anti-fatigue in the present application. However, deer antler and ginseng belong to the category of warming and tonifying traditional Chinese medicine, and excessive consumption or incompatible constitution can easily help to grow yang qi in the body, leading to symptoms such as mouth and tongue sores, sore throat and other symptoms of heat. Winter worm and summer grass is combined with such traditional Chinese medicines, which can easily boost the heat phenomenon, so the prescription needs to be optimized to harmonize the warm and cool properties of various drugs to achieve the purpose of reducing adverse reactions.

[0096] 80 cases of product trial were randomly divided into groups, and each group was taken 2 pills twice a day. Through clinical observation, the effect of the product was understood and adverse reactions were collected.

[0097] Performance: kidney yang deficiency symptoms, fatigue, mental outlook, resistance and other aspects of the improvement effect.

[0098] Symptoms of heat: the appearance of acne (or body), sores, dry throat, sore throat, gum bleeding, dry mouth and nose, irritability, feeling hot one or several.

[0099] Gastrointestinal discomfort symptoms: bloating, vomiting, diarrhea, constipation, one or several.

[0100] Table 5 Adverse reactions

[0101]

[0102] Compared with the examples, each control group appears different degrees of adverse reactions such as heat and gastrointestinal discomfort. The difference between the example and the control is that by combining dendrobium officinale, ligustrum lucidum and other medicines, yin and yang are balanced, which not only helps the yang to be assisted and to be infinite, but also prevents the yang-tonifying medicine from being too warm and dry, realizes the balance of yin and yang of the whole prescription, achieves the effect of "seeking yang in yin", and greatly reduces the probability of adverse reactions while maintaining the efficacy of the prescription.

[0103] Use case

[0104] Yu, 32 years old, department manager. Poor immunity, frequent colds, easy to feel tired, poor physical condition. After taking the example product for more than 2 months, the physical condition improved significantly, with high energy during the day, no more colds, and less symptoms of waist and back pain, and more stable sleep at night.

[0105] Zhou, 51 years old, company president. Poor spirit, easy to fatigue, afraid of cold. After taking the example product for 1 month, the body fatigue was reduced, the energy was high at work, and the symptoms of cold disappeared.

[0106] Ji, 42 years old, company president. Poor spirit, poor physical condition, mild rhinitis. After taking the control 1 product for 2 months, the mental state improved, the physical condition improved, and the rhinitis symptoms also improved, with the case of taking heat.

[0107] Duan, 43 years old, businessman. High work pressure, irregular life, poor mental state. After taking the control 2 product for 1 month, the mental state improved, but some were prone to heat.

[0108] Gan, 48 years old, businessman. Easy to fatigue, lack of energy. After taking the control 3 product for 1 month, the fatigue decreased, but the heat was also more obvious.

[0109] Test example 2 anti-fatigue function test

[0110] According to the anti-fatigue function test method in the Technical Standard for Health Food Inspection and Evaluation, 160 SPF Kunming male mice were selected. According to the daily recommended dosage of Example 2, three dose groups of low, medium and high were designed.

[0111] Weighted swimming test: the mice were continuously gavaged for 30 days, 30 min after the last administration, the mice were placed in a swimming box with 5% body weight of lead skin at the root of the tail, and the time from swimming to death was observed.

[0112] Table 6 Weighted swimming test results

[0113]

[0114] Blood lactic acid accumulation and clearance test: the mice were continuously gavaged for 30 days, 30 min after the last administration, the mice were put into water and swam for 10 min, blood was taken three times before swimming, immediately after swimming and 20 min after swimming to determine the blood lactic acid value.

[0115] Table 7 Blood lactic acid value determination results before swimming

[0116]

[0117] Table 8 Blood lactic acid value determination results after swimming

[0118]

[0119] Table 9 Blood lactic acid value determination results after swimming rest

[0120]

[0121] Table 10 Influence of blood lactic acid area under the curve

[0122]

[0123]

[0124] Serum urea nitrogen test: the mice were continuously gavaged for 30 days, 30 min after the last administration, the mice were put into water and swam for 90 min, and after 60 min of rest, the eyeball was taken to determine the serum urea nitrogen content.

[0125] Table 11 Influence of serum urea nitrogen

[0126]

[0127] Liver glycogen test: the mice were continuously gavaged for 30 days, 30 min after the last administration, the liver was taken to determine the liver glycogen content.

[0128] Table 13 Influence of liver glycogen content

[0129]

[0130] The function test results show that the low-dose group can significantly prolong the weight-bearing swimming time of mice, the medium-dose group can significantly reduce the blood lactic acid value and the area under the lactic acid curve after swimming of mice, the medium-dose and high-dose groups can significantly reduce the serum urea nitrogen value of mice, and the high-dose group can significantly increase the liver glycogen content of mice. According to the anti-fatigue function evaluation procedure, the test results are comprehensively determined, and the traditional Chinese medicine composition has an anti-fatigue function.

[0131] The above is a preferred embodiment of the present application, but the protection scope of the present application is not limited thereto, and any skilled person in the art can make changes and modifications within the technical scope disclosed herein, which shall belong to the scope of the present application.

Claims

1. A traditional Chinese medicine composition for improving kidney yang deficiency and resisting fatigue, characterized in that, The Chinese medicine composition is composed of the following raw materials by weight: Cordyceps sinensis 10-50 parts, deer antler 10-50 parts, ginseng 10-50 parts, Dendrobium officinale 10-50 parts, and Ligustrum lucidum 10-50 parts.

2. The traditional Chinese medicine composition according to claim 1, characterized in that, The Chinese medicine composition is composed of the following raw materials by weight: Cordyceps sinensis 15-30 parts, deer antler 15-30 parts, ginseng 20-40 parts, Dendrobium officinale 20-40 parts, and Ligustrum lucidum 20-40 parts.

3. A method for preparing the traditional Chinese medicine composition according to claim 1 or 2, characterized in that, The method comprises the following steps: Step 1: powdering or slicing Cordyceps sinensis, deer antler, ginseng, Dendrobium officinale, and Ligustrum lucidum; Step 2: adding the raw materials treated in Step 1 into water or ethanol for reflux extraction, and then filtering, concentrating, and drying the extract to obtain a Chinese medicine extract; Step 3: adding the extract obtained in Step 2 into food or medicine and adding a suitable amount of excipient, and then processing the mixture according to a conventional preparation process to obtain a required dosage form.

4. The production method according to claim 3, characterized by, The dosage form of the Chinese medicine composition includes, but is not limited to, tablets, capsules, granules, oral liquid, pills, syrup, and other oral dosage forms.

5. The Chinese medicine composition of claim 1 or 2 is used for preparing a health food or medicine for improving kidney yang deficiency and resisting fatigue.

6. Use according to claim 5, characterized in that, The amount of the Chinese medicine composition added in the health food or medicine is 30%-90%.

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