Herbicide for preventing and controlling field weeds

Abstract

The invention belongs to the technical field of herbicides, and particularly relates to a herbicide for preventing and controlling field weeds, the active components of the herbicide are formed by binary compounding of cyclopyridazinofop-p-methyl and pyrazol-quinclorac-ethyl, or ternary compounding of cyclopyridazinofop-p-methyl, pyrazol-quinclorac-ethyl and tefuryltrione. Compared with the prior art, the weeding composition has the advantages that the cyclopyridazinate is compounded with the pyrazalofop-p-ethyl, or the cyclopyridazinate is compounded with the pyrazalofop-p-ethyl and the tefuryltrione, so that the control effect on gramineous weeds such as barnyard grass in the field can be improved, the spraying dosage of a herbicide can be reduced, the control cost can be reduced, and meanwhile, the generation of crop phytotoxicity can be reduced. Besides, the herbicidal action mechanism of the cyclamefone in the herbicide is different from that of other components, so that weeds can be prevented and removed from different action sites when the herbicide is used, the development and accumulation of drug resistance of the weeds are slowed down, and the updating period of the herbicide can be prolonged. In conclusion, the invention can provide support for development of novel efficient herbicides.

Description

Technical Field

[0001] This invention belongs to the field of herbicide technology, specifically relating to a herbicide for controlling weeds in fields. Background Technology

[0002] Currently, herbicides are the most economical, effective, and convenient means of controlling weeds in farmland. However, the long-term use of single-component or homogeneous herbicides, and the unscientific use of large doses to improve efficacy, have led to problems such as herbicide resistance in weeds, frequent herbicide damage, and environmental pollution. Therefore, the development of new and highly efficient herbicides is of great significance.

[0003] Cyclopyrimorate is a phenoxypyridazine herbicide, CAS: 499231-24-2, with the following structural formula: .

[0004] According to the classification of the Human Resistant Herbicide Action Committee (HRAC), cyclopyridazine belongs to Group 33, the phenoxypyridazine structural type, and is the only active ingredient in this group. Cyclopyridazine is a solanesanoyltransferase (HST) inhibitor, and its target site is a novel site among commercially available herbicides. It can also be used to control weeds resistant to acetolactate synthase (ALS) inhibitors.

[0005] Pyraquinate is a benzoylpyrazole herbicide based on the quinazolinedione structure. The introduction of a pyrazole group into its quinazolinedione parent structure gives pyraquinate better systemic conductivity and rapid action. Furthermore, the introduction of an N,N-diethylcarbamate group at the 5-position of the pyrazole ring enhances its bioactivity and selectivity. CAS: 2378093-62-8, structural formula as follows: .

[0006] Pyrazoquinazon is an HPPD inhibitor that inhibits the activity of key pigment enzymes that control photosynthesis in plants, thus hindering the conversion of their substrates into homogentisic acid. This prevents the normal synthesis of tocopherol and plastoquinone, affecting the synthesis of carotenoids in the target plant and disrupting normal photosynthesis, ultimately leading to the plant's death.

[0007] Tefuryltrione is a benzoylcyclohexanedione herbicide, CAS: 473278-76-1. It is a 4-hydroxyphenylpyruvate dioxygenase (HPPD) inhibitor, which inhibits the synthesis of pigments essential for plant growth. It is absorbed and rapidly translocated through roots, stems, buds, and leaves, ultimately affecting the biosynthesis of carotenoids. After being treated, weeds exhibit leaf whitening, followed by necrosis of meristematic tissue. Summary of the Invention

[0008] The purpose of this invention is to provide a herbicide for controlling weeds in the field, in order to solve the problems caused by the long-term unscientific use of herbicides.

[0009] To achieve the above objectives, the present invention provides the following technical solution: A herbicide for controlling weeds in fields, the active ingredient of which is a binary compound of cyclopyridoxine and pyraclostrobin, or a ternary compound of cyclopyridoxine, pyraclostrobin and furazolidone.

[0010] Furthermore, the mass ratio of the compound of cyclopyridazine and pyraclostrobin is 1-8:20-1.

[0011] Furthermore, the mass ratio of the compound of cyclopyridazine and pyraclostrobin is 1:4.

[0012] Furthermore, the mass ratio of the compound of cyclopyridazine, pyraclostrobin, and furazolidone is 1:1:1-6.

[0013] Furthermore, the mass ratio of the compound of cyclopyridazine, pyraclostrobin and furazolidone is 1:1:3 or 1:1:6.

[0014] Furthermore, the active ingredient accounts for 0.1-85% of the total mass of the herbicide, with the remainder being pesticide-permissible auxiliary ingredients and antidotes.

[0015] Furthermore, the active ingredient accounts for 6-45% of the total mass of the herbicide.

[0016] Compared with the prior art, the present invention has the following beneficial effects: (1) The present invention combines cyclopyridazine with pyraclostrobin, or combines cyclopyridazine with pyraclostrobin and furazolidone, which can improve the control effect on barnyard grass and other grass weeds in the field, reduce the amount of herbicide sprayed, reduce the control cost, and also help reduce the occurrence of pesticide damage to crops.

[0017] (2) The herbicide of the present invention has a different mechanism of action than other components. When using the herbicide of the present invention, weeds can be controlled from different sites of action, so as to slow down the development and accumulation of weed resistance and extend the replacement cycle of herbicides.

[0018] In summary, this invention can provide support for the development of novel and highly efficient herbicides. Detailed Implementation

[0019] The following is a clear and complete description of the technical solution of this invention patent. Obviously, the described embodiments are some, but not all, of the embodiments of this invention.

[0020] Example: Indoor bioactivity test of cyclopyridazine compound 1. Test weeds barnyard grass ( Echinochloa crusgalli The seeds were collected from farmland in the suburbs of Xinyang City, Henan Province.

[0021] 2. Test reagents 98% cyclopyridazine, 95% pyraclostrobin, and 97% furazolidone were all sourced from the laboratory of Xinyang Academy of Agricultural Sciences.

[0022] The test agent was dissolved in solvent and diluted with a 0.1% Tween-80 aqueous solution to prepare a single-agent stock solution of 2000 mg / L. Based on the results of the preliminary test, multiple formulations were prepared. During the later foliar spraying, the single-agent stock solution and each formulation were diluted with a 0.1% Tween-80 aqueous solution to create five mass concentration gradients. All reagents were prepared and used immediately.

[0023] 3. Test Methods The toxicity of single and mixed herbicides of cyclopyridaben, pyraclostrobin, and furazolidone to tested weeds was determined using a foliar spray method. Specifically, field soil was air-dried, sieved, and filled to 3 / 4 full of perforated plastic pots (15cm×12cm×8cm). The soil was thoroughly moistened using bottom irrigation. Seeds of the tested weeds, soaked and germinated until showing white tips, were evenly sown in the plastic pots (35 seeds / pot), and covered with 0.3cm of fine soil. The pots were then placed in a greenhouse with an average daily temperature of 25±2℃, 12h light, and 70±5% relative humidity, and the soil was kept moist. When the seedlings reached the 3-leaf stage, thinning was performed, leaving 20 uniformly growing seedlings per pot for bioassay.

[0024] The 3WPSH-500D bioassay spray tower (spray pressure 0.3MPa, nozzle flow rate 90mL / min, main shaft rotation speed 6r / min) of the Nanjing Institute of Agricultural Mechanization, Ministry of Agriculture and Rural Affairs was used to spray the stems and leaves of weed seedlings. Each concentration of pesticide solution was replicated 5 times, and a 0.1% Tween-80 aqueous solution was set as a blank control.

[0025] Fourteen days after application, the fresh weight of the above-ground portion of the weeds was weighed, and the fresh weight control efficacy was calculated. Regression analysis was performed on the logarithmic values ​​of pesticide dosage and the probability of control efficacy to calculate the efficacy (ED) of single-dose and mixtures with different ratios. 50 The co-toxicity coefficient (CTC value) of the mixture was calculated using the Sun Yunpei method.

[0026] 4. Calculation Method

[0027] In the above formula: E --Fresh weight efficacy (%)C --Comparison of fresh weight of the above-ground portion of weeds (g); T --Fresh weight (g) of the aboveground portion of the weeds.

[0028]

[0029] In the above formula: WE HAD --Measured toxicity index of the mixture; S --ED of standard reagents 50 The unit is g ai / hm2; M --ED of the test reagent 50 The unit is g ai / hm 2 .

[0030]

[0031] In the above formula: TTI --Theoretical toxicological index of the mixture; OF A --Toxicity index of drug A; P A --Percentage content of drug A in the mixture, expressed as percentage (%). OF B --Toxicity index of drug B; P B --The percentage content of drug B in the mixture, expressed as a percentage (%).

[0032]

[0033] In the above formula: CTC --Cotoxicity coefficient; WE HAD --Measured toxicity index of the mixture; TTI --Theoretical toxicity index of mixed formulations.

[0034] 5. Pharmaceutical Evaluation Based on the cotoxicity coefficient ( CTC Evaluation of the type of action of drug combination: CTC≤80 indicates antagonistic effect, 80<CTC<120 indicates additive effect, and CTC≥120 indicates synergistic effect. The results are shown in Table 1-2.

[0035]

[0036] As shown in Table 1, when cyclopyridazine and pyraclostrobin are combined in a mass ratio of 1-8:20-1, the co-toxicity coefficient of the combination for controlling barnyard grass is greater than 120, which shows a synergistic effect and can improve the control effect on barnyard grass.

[0037]

[0038] Table 2 shows that when cyclopyridaben and pyraclostrobin are combined in a 1:1 mass ratio, the co-toxicity coefficient for controlling barnyardgrass is 187.207; when cyclopyridaben and furazolidone are combined in a 1:1 mass ratio, the co-toxicity coefficient for controlling barnyardgrass is 122.859; and when pyraclostrobin and furazolidone are combined in a 1:1 mass ratio, the co-toxicity coefficient for controlling barnyardgrass is 125.910. This indicates that the combination of cyclopyridaben, pyraclostrobin, and furazolidone in any pair exhibits a synergistic effect in controlling barnyardgrass.

[0039] When cyclopyridaben is combined with pyraclostrobin and furazolidone in a mass ratio of 1:1:1-6, the co-toxicity coefficient of the combination for controlling barnyard grass is greater than 120, showing a synergistic effect and improving the control effect on barnyard grass. In particular, when the mass ratios of the combination are 1:1:3 and 1:1:6, the co-toxicity coefficients are 387.960 and 191.749, respectively, which are greater than the co-toxicity coefficients of the 1:1 combination, indicating a better synergistic effect.

[0040] In summary, this invention, by combining cyclopyridaben with pyraclostrobin, or by combining cyclopyridaben with pyraclostrobin and furazolidone, can improve the control efficacy against barnyardgrass and other grassy weeds in the field, reduce the amount of herbicide applied, lower control costs, and also help reduce crop damage caused by herbicides. Furthermore, the herbicidal mechanism of cyclopyridaben in this invention differs from that of the other components. Using this herbicide allows for control of weeds at different sites of action, slowing the development and accumulation of herbicide resistance in weeds and extending the herbicide replacement cycle. Therefore, this invention can support the development of novel, highly efficient herbicides.

Claims

1. A herbicide for controlling weeds in fields, characterized in that, Its active ingredients are a binary compound of cyclopyridoxine and pyraclostrobin, or a ternary compound of cyclopyridoxine, pyraclostrobin and furazolidone.

2. The herbicide for controlling field weeds according to claim 1, characterized in that, The mass ratio of the compound of cyclopyridazine and pyraclostrobin is 1-8:20-1.

3. The herbicide for controlling field weeds according to claim 1, characterized in that, The mass ratio of the compound of cyclopyridazine and pyraclostrobin is 1:

4.

4. The herbicide for controlling field weeds according to claim 1, characterized in that, The mass ratio of the compound of cyclopyridazine, pyraclostrobin and furazolidone is 1:1:1-6.

5. The herbicide for controlling field weeds according to claim 1, characterized in that, The mass ratio of the compound of cyclopyridazine, pyraclostrobin and furazolidone is 1:1:3 or 1:1:

6.

6. The herbicide for controlling field weeds according to claim 1, characterized in that, The active ingredient accounts for 0.1-85% of the total mass of the herbicide, with the remainder being pesticide-safe auxiliary ingredients and antidotes.

7. The herbicide for controlling field weeds according to claim 5, characterized in that, The active ingredient accounts for 6-45% of the total mass of the herbicide.

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