Grinding device for tablet medicine detection

Abstract

The invention discloses a grinding device for tablet medicine detection, and relates to the technical field of medicine grinding. The grinding device comprises a motor mounting base, a high-speed driving motor arranged in the motor mounting base, a grinding machine tool apron and a grinding tool rotationally arranged on the grinding machine tool apron, and a rotating shaft of the grinding tool is in transmission connection with a driving shaft of the high-speed driving motor through a tool apron connecting wheel. A grinding cup cover is detachably arranged at the top of the grinding machine tool apron, a discharging port extending towards the outer side is formed in the top of the grinding cup cover, a spiral blade extending into the grinding cup cover is arranged in the discharging port, and a rotary knob used for driving the spiral blade to rotate is arranged on the outer side of the discharging port. One end of the knob away from the helical blade is provided with a socket for connecting a test tube. The medicine powder is discharged out of the grinding cup cover and transferred into the test tube on the premise that the grinding machine tool apron is not opened, the amount of atomized medicine powder entering air is reduced, and experimenters can conveniently transfer the medicine powder into the test tube.

Description

Technical Field

[0001] This invention relates to the field of drug grinding technology, specifically a grinding device for testing tablet drugs. Background Technology

[0002] The grinding device for tablet drug testing is a core pretreatment equipment in the process of drug quality control, component analysis and research and development. Its core function is to quickly, uniformly and without contamination grind solid tablets into powder of a specific particle size, so as to provide samples that meet the requirements of the grinding device for tablet drug testing for subsequent testing experiments, and ensure the accuracy, repeatability and reliability of the test results.

[0003] Existing technology for grinding devices used to grind tablet pharmaceuticals, such as Figure 14As shown, the main structure includes a motor mounting base 1 with a round cup shape. A high-speed drive motor is fixed inside the motor mounting base 1, with a rotational speed generally between 20,000 r / min and 30,000 r / min. The top of the motor mounting base 1 is provided with a downwardly recessed fixing groove 11. The drive shaft of the high-speed drive motor passes through the motor mounting base 1 and extends into the fixing groove 11. It also includes a grinding blade 22 and a grinding machine tool holder 21 for mounting the grinding blade 22. The grinding blade 22 is rotatably mounted on the grinding machine tool holder 21 via a rotating shaft. The grinding machine tool holder 21 and the motor mounting base 1 are detachably connected. The grinding machine tool holder 21 can be inserted into the fixing groove 11. The drive shaft of the high-speed drive motor located inside the motor mounting base 1 and the corresponding rotating shaft of the grinding blade 22 are connected by a tool holder connecting wheel 3. The system also includes a grinding cup cover 4, which is threaded to the top of the grinder blade holder 21. The grinding cup cover 4 encloses the grinding blade 22, thus forming a sealed grinding chamber between the grinder blade holder 21 and the grinding cup cover 4. When grinding tablets, the tablets to be ground are first placed around the grinding blade 22 on top of the grinder blade holder 21. Then, the grinding cup cover 4 is installed and fixed to the top of the grinder blade holder 21. The high-speed drive motor is then controlled to rotate, driving the grinding blade 22 to rotate at high speed through the blade holder connecting wheel 3 to grind the tablets. After grinding, the grinder blade holder 21 is removed from the motor mounting base 1. At this time, the grinder blade holder 21 and the grinding cup cover 4 are not separated. Then, the grinder blade holder 21 and the grinding cup cover 4 are inverted. The ground powdered tablets fall into the interior of the grinding cup cover 4 due to gravity. Generally, the operator will tap or shake the grinding cup cover to remove the tablets adhering to the grinder blade holder 21 and let them fall into the interior of the grinding cup cover 4. After the ground medicine powder is processed into the grinding cup 4, the grinding cup 4 forms a container for temporary storage of the medicine. Therefore, the grinding cup 4 is usually referred to as a grinding measuring cup on the grinder. When removing the ground medicine, the grinder blade holder 21 and the grinding cup 4 should be kept in the inverted state. Then, the grinder blade holder 21 is removed from the grinding cup 4, and the medicine inside the grinding cup 4 is poured onto weighing paper for further processing.

[0004] The grinding devices in the prior art described above have the following problems: 1. Because the grinding blade is used to grind the medicine, the grinding blade collides and rubs with the medicine and air while rotating at high speed. This causes the temperature of the air inside the grinding cup and the inner wall of the grinding cup near the grinding blade to rise, and the air pressure inside the grinding cup to increase. When the grinding machine blade holder is opened, some of the medicine powder will be atomized and sprayed into the air. The more medicine is sprayed into the air, the greater the impact on the experimental environment and the safety and health of the experimental personnel.

[0005] 2. The ground reagents may be used directly for testing, or they may be stored in test tubes for other treatments depending on the actual experimental needs, such as storage, high or low temperature treatment, or light treatment. All of these require storing the ground reagents in test tubes. Current technology requires pouring the ground reagents directly onto weighing paper and then transferring them from the weighing paper to the test tubes. Firstly, the transfer operation is cumbersome and affects experimental efficiency. Secondly, the transfer process uses tools such as spoons to manually transfer the reagents into the test tubes, which often results in reagents spilling from the test tube opening onto the experimental table, causing reagent loss. Summary of the Invention

[0006] The purpose of this invention is to provide a grinding apparatus for testing tablet pharmaceuticals, so as to solve the problems mentioned in the background art.

[0007] To achieve the above objectives, the present invention provides the following technical solution: a grinding device for tablet drug testing, comprising a motor mounting base and a high-speed drive motor disposed inside the motor mounting base, a grinding mill blade holder, and a grinding blade rotatably disposed on the grinding mill blade holder. The top of the motor mounting base is provided with a fixing groove for accommodating the grinding mill blade holder. The rotating shaft of the grinding blade is connected to the drive shaft of the high-speed drive motor via a blade holder connecting wheel. A grinding cup cover is detachably disposed on the top of the grinding mill blade holder. The top of the grinding cup cover is provided with an outwardly extending discharge port. A spiral blade extending into the grinding cup cover is disposed inside the discharge port. A knob for driving the spiral blade to rotate is disposed outside the discharge port. An insertion port for connecting a test tube is disposed at the end of the knob away from the spiral blade.

[0008] Preferably, a connecting sleeve is detachably connected to the outside of the discharge port, and the knob is rotatably mounted on the connecting sleeve.

[0009] Preferably, the knob is configured as a ring structure, and the inner ring surface of the knob is provided with a limiting ring one extending circumferentially thereon; the outer side of the connecting sleeve is provided with two limiting rings two extending circumferentially thereon, and the knob is sleeved on the outer side of the connecting sleeve with the limiting ring one located between the two limiting rings two.

[0010] Preferably, the outer side of the knob is provided with friction texture.

[0011] Preferably, the knob has a connecting shaft inside, and the spiral blade is coiled around the outside of the connecting shaft.

[0012] Preferably, it also includes an adapter, which is configured as a funnel-shaped structure. The feed end of the adapter forms a fixed interface that is plugged into the socket, and the discharge end of the adapter forms a test tube interface that is plugged into the test tube.

[0013] Preferably, the grinding cup cover is integrally formed with the discharge port, and the transition section between the grinding cup cover and the discharge port is rounded.

[0014] Preferably, the outer side of the discharge port is provided with an external thread, and the inner side of the connecting sleeve is provided with a corresponding internal thread. The connecting sleeve and the discharge port are connected in a detachable manner through the corresponding threads.

[0015] Compared with the prior art, the beneficial effects of the present invention are: 1. This invention enables the discharge of pharmaceutical powder from the grinding cup and its transfer to a test tube without opening the grinder blade holder, greatly reducing the amount of atomized pharmaceutical powder entering the air, thus minimizing the impact on the laboratory environment and the safety of laboratory personnel.

[0016] 2. This invention allows for the direct transfer of pharmaceutical powder into test tubes without opening the grinder blade holder, eliminating the need to first pour the powder onto weighing paper before transferring it to the test tube. This reduces operational steps and improves experimental efficiency.

[0017] 3. In this invention, the test tube is directly connected to the grinding cup, and the ground medicine powder is transferred into the test tube through the spiral blades. The medicine will not fall into the outside during the transfer process, thus avoiding the loss of medicine due to spillage during the transfer process.

[0018] 4. This invention, by incorporating a fixed groove in the adapter interface, can accommodate test tubes of various diameters, enhancing the versatility and practicality of the grinding device. When test tubes of different diameters are needed to collect pharmaceutical powder, simply select the appropriate adapter interface, insert its fixed interface into the socket, and then insert the test tube into the test tube interface to smoothly transfer the pharmaceutical powder. This design fully considers the diverse needs of actual experiments, greatly facilitating experimental operations. Attached Figure Description

[0019] Figure 1 This is a schematic diagram of the structure of the present invention; Figure 2 This is a partial structural schematic diagram of the present invention (the grinding cup cover is not shown); Figure 3 This is an exploded view of the present invention; Figure 4 The structure of the grinding machine tool holder in the prior art Figure 1 (With the grinding blade on one side); Figure 5 The structure of the grinding machine tool holder in the prior art Figure 2 (One side with the tool holder connecting wheel); Figure 6 This is a diagram showing the fit between the spiral blades and the grinding cup cover of the present invention; Figure 7This is an exploded view of part of the structure of the present invention; Figure 8 This is a partial structural schematic diagram of the present invention (the motor mounting base and the grinding machine tool holder are not shown). Figure 9 This is a diagram illustrating the fit between the knob and the connecting sleeve of the present invention. Figure 10 This is a schematic diagram of the connecting sleeve of the present invention; Figure 11 This is a schematic diagram of the structure of the knob of the present invention. Figure 1 ; Figure 12 This is a schematic diagram of the structure of the knob of the present invention. Figure 2 ; Figure 13 This is a diagram showing the grinding cup cover of the present invention in an inverted state; Figure 14 This is a structural diagram of a grinding device in the prior art; Figure 15 This is a diagram illustrating the fit between the tool holder connecting wheel and the existing technology.

[0020] In the picture: 1-Motor mounting bracket, 11-Fixing slot, 21-Grinding machine tool holder, 22-Grinding tool, 3-Tool holder connecting wheel, 4-Grinding cup cover, 41-Discharge port, 51-Knob, 52-Helical blade, 53-Connecting shaft, 54-Connecting arm, 55-Limiting ring one, 56-Socket, 6-Connecting sleeve, 61-Limiting ring two, 7-Adapter, 71-Fixed connector, 72-Test tube connector 8-Test tubes. Detailed Implementation

[0021] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0022] First, it should be noted that the grinding device for tablet drug testing given in this embodiment includes the following parts that are the same as those in the prior art: motor mounting base 1 and a high-speed drive motor (not shown in the figure) disposed inside the motor mounting base 1, grinding machine blade holder 21 and grinding blade 22 rotatably disposed on the grinding machine blade holder 21.

[0023] For ease of understanding and description, the main structure of the grinding device in the prior art is described below: like Figure 14 The motor mounting base 1 is usually designed in the shape of a round cup. The high-speed drive motor is fixed inside the motor mounting base 1. The top of the motor mounting base 1 is provided with a downwardly recessed fixing groove 11. The drive shaft of the high-speed drive motor passes through the motor mounting base 1 and extends into the fixing groove 11.

[0024] like Figure 4 , Figure 5 and Figure 14 The shape of the grinding machine cutter holder 21 corresponds to that of the fixing groove 11. The grinding cutter 22 is rotatably mounted on the top of the grinding machine cutter holder 21. The rotating shaft of the grinding cutter 22 is connected to the drive shaft of the high-speed drive motor via the cutter holder connecting wheel 3. The cutter holder connecting wheel 3 consists of two ratchet-equipped shaft discs (such as...). Figure 15 The ratchet teeth between the two tool holder connecting wheels 3 mesh with each other to achieve rotational transmission. After the grinding machine tool holder 21 is inserted into the fixed groove 11, the two tool holder connecting wheels 3 mesh with each other, and the high-speed drive motor is started.

[0025] The top of the grinding machine tool holder 21 is detachably equipped with a grinding cup cover 4. The grinding cup cover 4 is usually connected to the grinding machine tool holder 21 by threads. The top of the grinding machine tool holder 21 and the area around the grinding blade 22 are provided with internal threads. The cup opening of the grinding cup cover 4 is provided with corresponding external threads. When fixing the grinding cup cover 4, the external threads at the cup opening of the grinding cup cover 4 are screwed to the corresponding internal threads at the top of the grinding machine tool holder 21.

[0026] The above describes the main structure of the grinding device in the prior art. It also includes other technical features less relevant to this embodiment, such as the controller for the high-speed motor, which will not be elaborated upon here. For specific usage instructions, please refer to the description in the background section above.

[0027] like Figures 6 to 12 As shown, this embodiment differs from the prior art in that: the top of the grinding cup cover 4 is provided with an outwardly extending outlet 41, the outlet 41 is provided with a spiral blade 52 extending into the interior of the grinding cup cover 4, the outer side of the outlet 41 is provided with a knob 51 for driving the spiral blade 52 to rotate, and the end of the knob 51 away from the spiral blade 52 is provided with a socket 56 for connecting a test tube 8.

[0028] Specifically, in this embodiment, the grinding cup cover 4 and the discharge port 41 are integrally formed, and can be manufactured by injection molding or compression molding. The transition section between the grinding cup cover 4 and the discharge port 41 is rounded to improve the quality of the ground medicine powder inside the grinding cup cover 4.

[0029] Furthermore, a connecting sleeve 6 is detachably connected to the outer side of the discharge port 41, and the knob 51 is rotatably mounted on the connecting sleeve 6. The purpose of this design is to facilitate the removal of the knob 51 and the spiral blade 52 from the grinding cup cover 4 via the detachable connecting sleeve 6, thereby facilitating the cleaning of the grinding cup cover 4 and the spiral blade 52.

[0030] In one specific embodiment, the outer side of the discharge port 41 is provided with an external thread, and the inner side of the connecting sleeve 6 is provided with a corresponding internal thread. The connecting sleeve 6 and the discharge port 41 are connected by the corresponding threads to form a detachable mating connection.

[0031] As one specific implementation method, such as Figures 9 to 12 As shown, the knob 51 is configured in a ring shape. The inner ring surface of the knob 51 has a limiting ring 55 extending circumferentially therein. The outer side of the connecting sleeve 6 has two limiting rings 61 extending circumferentially therein. The knob 51 is fitted onto the outer side of the connecting sleeve 6, with the limiting ring 55 positioned between the two limiting rings 61. Thus, the limiting rings 61 restrict the knob 51 to the outer side of the connecting sleeve 6, allowing the knob 51 to rotate only along the axis of the connecting sleeve 6.

[0032] Furthermore, the outer side of the knob 51 is provided with friction texture to increase the contact friction of the knob 51 surface, making it easier to twist the knob 51 to rotate.

[0033] In a preferred embodiment, the inner diameter of the knob 51 is the same as the outer diameter of the connecting sleeve 6, allowing the knob 51 to better fit against the outer wall of the connecting sleeve 6 for rotation, thus ensuring rotational stability. The spacing between the two limiting rings 61 is the same as the thickness of the limiting ring 55, also to ensure the rotational stability of the knob 51.

[0034] It should be noted that in this embodiment, both the knob 51 and the connecting sleeve 6 are made of plastic. Therefore, the limiting ring 55 can be installed between the two limiting rings 61 through an elastic deformation assembly method. Alternatively, one limiting ring 61 can be first set on the outer wall of the connecting sleeve 6, then the knob 51 can be fitted onto the outer wall of the connecting sleeve 6, and then the other limiting ring 61 can be fixed to the outer wall of the connecting sleeve 6 by plastic welding. The above two assembly methods are existing conventional technologies, and the assembly methods are not within the scope of this solution to be discussed in detail, so they will not be elaborated further.

[0035] Specifically, in this embodiment, a connecting shaft 53 is provided inside the knob 51. The connecting shaft 53 is located at the center of the knob 51 and is arranged coaxially with the knob 51. The connecting shaft 53 is fixedly connected to the inner wall of the knob 51 through a connecting arm 54. The spiral blade 52 is coiled around the outside of the connecting shaft 53.

[0036] Furthermore, this embodiment also includes an adapter 7, which is configured in a funnel shape. The feed end of the adapter 7 forms a fixed interface 71 that engages with the socket 56, and the discharge end of the adapter 7 forms a test tube interface 72 that engages with the test tube 8. Therefore, the diameter of the fixed interface 71 is fixed and is the same as the diameter of the socket 56. The diameter of the test tube interface 72 is designed to accommodate test tubes of different diameters, indicating that the adapter 7 is an auxiliary interface designed to accommodate the connection between test tubes of various diameters and the socket 56. Therefore, multiple adapters 7 are designed to accommodate the diversity of test tubes, and the diameter of the test tube interface 72 of each adapter 7 is the same as the inner diameter of a corresponding test tube. In this way, when a corresponding test tube cannot be directly inserted into the socket 56, the connection between the socket 56 and the test tube is achieved using a suitable adapter 7.

[0037] Working principle: like Figures 1 to 3 When grinding tablets, first place the tablets to be ground around the grinding blades 22 on top of the grinder blade holder 21. Then, install the grinding cup 4 and fix it to the top of the grinder blade holder 21. Next, control the high-speed drive motor to rotate, which drives the grinding blades 22 to rotate at high speed through the blade holder connecting wheel 3 to grind the tablets. After grinding, remove the grinder blade holder 21 from the motor mounting base 1. At this time, the grinder blade holder 21 and the grinding cup 4 are not separated. Then, invert the grinder blade holder 21 and the grinding cup 4 (e.g., ...). Figure 13 As shown in the diagram, the ground powdered medicine falls into the interior of the grinding cup 4 due to gravity. By tapping or shaking the grinding cup 4, the medicine adhering to the grinding machine cutter holder 21 is cleaned off and falls into the interior of the grinding cup 4.

[0038] Continue to keep the grinder blade holder 21 and grinding cup 4 in the inverted state, then turn knob 51. As knob 51 turns, it drives the spiral blade 52 to rotate sequentially through connecting arm 54 and connecting shaft 53. Under the action of the spiral, the spiral blade 52 transfers the ground medicine inside the grinding cup 4 to the test tube 8. Note that when turning knob 51, ensure that the medicine powder is discharged outwards.

[0039] It should be noted that, in traditional grinders, the amount of atomized pharmaceutical powder entering the air after the grinding cup 4 is opened depends primarily on the size of the cup opening area. A larger opening area results in more atomized pharmaceutical powder entering the air. Secondly, the internal temperature of the grinding cup 4 at the time of opening also plays a role. Higher temperatures lead to higher internal air pressure, resulting in a higher airflow velocity and more pharmaceutical powder being carried out by the airflow. In existing technology, the diameter of the grinding cup opening in common laboratory pharmaceutical grinders is approximately 9 cm, with an opening area of ​​about 63.6 cm². 2 Common test tubes used for storing pharmaceutical powders typically have a diameter of 1-3 cm. Taking a test tube with a maximum diameter of 3 cm as an example, its opening area is approximately 7.1 cm², nearly nine times smaller than the opening area of ​​the grinding cup. This means that when the grinding cup is opened, a large amount of pharmaceutical powder will enter the air due to airflow and diffusion. In this embodiment, the pharmaceutical powder is directly transferred to the test tube via spiral blades, reducing the amount of atomized pharmaceutical powder entering the air by at least 88.9%. Secondly, in this embodiment, since the test tube is far from the grinder blade holder 21, the temperature of the test tube itself and its internal space is relatively lower than the temperature inside the grinding cup 4. After the pharmaceutical powder is transferred to the inside of the test tube via spiral blades 52, the powder comes into contact with the test tube and exchanges heat, lowering the temperature of the powder and reducing the overall air pressure inside the grinding cup 4 and the test tube. This further reduces the amount of pharmaceutical powder entering the air when the test tube is opened.

[0040] By using the aforementioned method of discharging the chemical powder, it is possible to discharge the powder from the grinding cup 4 and transfer it to the test tube without opening the grinder blade holder 21. This significantly reduces the amount of powder entering the air, minimizing its impact on the laboratory environment and the safety of laboratory personnel. Furthermore, it eliminates the need to pour the powder onto weighing paper before transferring it to the test tube, reducing operational steps, improving experimental efficiency, and preventing spillage during transfer. Moreover, the adapter 7 allows for the use of test tubes of various diameters, enhancing the versatility and practicality of the grinding device. When different diameter test tubes are needed to collect the powder, simply select the appropriate adapter 7, insert its fixing interface 71 into the socket 56, and then insert the test tube into the test tube interface 72 to smoothly transfer the powder. This design fully considers the diverse needs of actual experiments, greatly facilitating experimental operations.

[0041] It will be apparent to those skilled in the art that the present invention is not limited to the details of the exemplary embodiments described above, and that the invention can be implemented in other specific forms without departing from its spirit or essential characteristics. Therefore, the embodiments should be considered in all respects as exemplary and non-limiting, and the scope of the invention is defined by the appended claims rather than the foregoing description. Thus, all variations falling within the meaning and scope of equivalents of the claims are intended to be included within the present invention. No reference numerals in the claims should be construed as limiting the scope of the claims.

Claims

1. A grinding device for testing tablet pharmaceuticals, comprising a motor mounting base (1), a high-speed drive motor disposed inside the motor mounting base (1), a grinding mill blade holder (21), and a grinding blade (22) rotatably disposed on the grinding mill blade holder (21). The top of the motor mounting base (1) is provided with a fixing groove (11) for accommodating the grinding mill blade holder (21). The rotating shaft of the grinding blade (22) is connected to the drive shaft of the high-speed drive motor via a blade holder connecting wheel (3). A grinding cup cover (4) is detachably disposed on the top of the grinding mill blade holder (21). The device is characterized in that: The top of the grinding cup cover (4) is provided with an outwardly extending outlet (41), and a spiral blade (52) extending into the inside of the grinding cup cover (4) is provided inside the outlet (41). A knob (51) for driving the spiral blade (52) to rotate is provided on the outside of the outlet (41). A socket (56) for connecting a test tube (8) is provided at the end of the knob (51) away from the spiral blade (52).

2. The grinding apparatus for testing tablet pharmaceuticals according to claim 1, characterized in that: A connecting sleeve (6) is detachably connected to the outside of the discharge port (41), and the knob (51) is rotatably mounted on the connecting sleeve (6).

3. The grinding apparatus for testing tablet pharmaceuticals according to claim 2, characterized in that: The knob (51) is configured as a ring structure, and a limiting ring (55) extending circumferentially is provided on the inner ring surface of the knob (51); two limiting rings (61) extending circumferentially are provided on the outer side of the connecting sleeve (6), and the knob (51) is sleeved on the outer side of the connecting sleeve (6) and the limiting ring (55) is located between the two limiting rings (61).

4. The grinding apparatus for testing tablet pharmaceuticals according to claim 1, characterized in that: The knob (51) has a friction texture on its outer side.

5. A grinding apparatus for testing tablet pharmaceuticals according to claim 1, characterized in that: The knob (51) has a connecting shaft (53) inside, and the spiral blade (52) is coiled around the outside of the connecting shaft (53).

6. The grinding apparatus for testing tablet pharmaceuticals according to claim 1, characterized in that: It also includes an adapter (7), which is configured as a funnel-shaped structure. The feed end of the adapter (7) forms a fixed interface (71) that is plugged into the socket (56), and the discharge end of the adapter (7) forms a test tube interface (72) that is plugged into the test tube (8).

7. The grinding apparatus for testing tablet pharmaceuticals according to claim 1, characterized in that: The grinding cup cover (4) is integrally formed with the discharge port (41), and the transition section between the grinding cup cover (4) and the discharge port (41) is rounded.

8. A grinding apparatus for testing tablet pharmaceuticals according to claim 2, characterized in that: The outer side of the discharge port (41) is provided with an external thread, and the inner side of the connecting sleeve (6) is provided with a corresponding internal thread. The connecting sleeve (6) and the discharge port (41) are connected by the corresponding threads to form a detachable mating connection.

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