Marker for prenatal suicidal ideation

By detecting the abundance of gut microbiota markers in pregnant women's feces and constructing a diagnostic model using machine learning algorithms, the problem of screening for prenatal suicidal ideation has been solved, achieving efficient and safe diagnosis and intervention of prenatal suicidal ideation and improving maternal and infant health.

CN121629042BActive Publication Date: 2026-06-05WUHAN UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
WUHAN UNIV
Filing Date
2026-02-05
Publication Date
2026-06-05

AI Technical Summary

Technical Problem

The lack of an effective prenatal suicidal ideation screening mechanism in existing technologies makes it impossible to identify and intervene in pregnant women's suicidal ideas in a timely manner, which affects the physical and mental health of mothers and infants.

Method used

By detecting the abundance of gut microbiota markers in fecal samples from pregnant women, nine bacterial genera were screened using high-throughput sequencing technology. A diagnostic model was then constructed using machine learning algorithms to achieve a highly specific and sensitive diagnosis of prenatal suicidal ideation.

Benefits of technology

It provides a highly specific and sensitive method for diagnosing prenatal suicidal ideation. It is simple to operate, safe and non-invasive, reduces the rate of missed diagnosis, and can intervene in a timely manner to improve the physical and mental health of mothers and infants.

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Abstract

The present application relates to the technical field of microorganisms, and particularly relates to a prepartum suicidal ideation marker, which comprises an intestinal flora, and the intestinal flora comprises Bacteroides, Sutterella, Parabacteroides, Lachnospiraceae, Oscillospiraceae, Actinomyces, Gemella, Streptococcus and Oribacterium. By detecting the abundance of the above-mentioned flora markers in the fecal sample of a pregnant woman, the risk of prepartum suicidal ideation of the pregnant woman can be effectively diagnosed, a new perspective is provided for the study of the potential mechanism of suicidal ideation, and the diagnosis method has high specificity, high sensitivity and high accuracy, is simple and safe and non-invasive, has low medical cost, has low misdiagnosis rate, is conducive to timely intervention and inhibition of suicidal ideation of the pregnant woman, improves the physical and mental health of the mother and infant, provides accurate intervention guidance for the clinic, and is suitable for clinical popularization and application.
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Citation Information

Patent Citations

  • CN111500505A

  • CN120113803A