Bacillus cereus bacteriophage WAH1 and application thereof

By providing Bacillus cereus phage WAH1, the problems of insufficient existing phage resources and reduced activity under low temperature conditions are solved, achieving broad-spectrum and efficient lysis of Bacillus cereus and effective control of contamination in food.

CN122278780APending Publication Date: 2026-06-26SOUTH CHINA AGRICULTURAL UNIVERSITY
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
SOUTH CHINA AGRICULTURAL UNIVERSITY
Filing Date
2026-03-19
Publication Date
2026-06-26

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Abstract

This invention discloses a Bacillus cereus bacteriophage, WAH1, and its applications. The Bacillus cereus bacteriophage WAH1, with accession number GDMCC No:67732-B1, does not carry drug resistance or virulence factors, can specifically lyse Bacillus cereus, and has a broad host spectrum. This bacteriophage possesses a short latency period and high burst capacity, enabling efficient lysis of host bacteria. Furthermore, WAH1 exhibits strong tolerance to factors such as temperature, pH, and osmotic pressure, demonstrating strong environmental adaptability and resistance to inactivation during application. This bacteriophage shows significant inhibitory effects on the target bacteria in liquid culture media, milk, and rice. In summary, WAH1 bacteriophage shows promising application prospects in controlling Bacillus cereus contamination in food.
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