Aspergillus flavus toxin b1 degrading strain and application thereof

By using Bacillus paralichrysogenus IMAULM4, the problems of low efficiency and poor safety of existing AFB1 degradation strains have been solved, achieving efficient and safe degradation of aflatoxin B1 in grains and feed, and possessing cellulose degradation and antibacterial capabilities.

CN122405503APending Publication Date: 2026-07-17INNER MONGOLIA AGRICULTURAL UNIVERSITY
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Patent Information

Application Number
CN202610774627.5
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2026-06-01
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

Existing AFB1 degrading strains suffer from low degradation efficiency, poor adaptability, and insufficient safety, which limits their application in actual production.

Method used

A strain of Bacillus paralicheniformis, IMAULM4, is provided. It exhibits good resistance to acid, bile salts, and artificial gastrointestinal fluids, as well as cellulose degradation and pathogen inhibition capabilities. It can secrete heat-stable degrading enzymes, making it suitable for degrading aflatoxin B1 in grains and feed.

Benefits of technology

This strain can efficiently destroy the molecular structure of toxins and significantly reduce the toxin content in the substrate. It has both probiotic and antibacterial properties, making it suitable for green detoxification of grains and feeds. It is highly safe, adaptable, and has a stable enzyme system.

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Abstract

本发明涉及微生物技术领域,具体涉及一株能降解黄曲霉毒素B1的菌株及应用,所述菌株为副地衣芽孢杆菌(Bacillus paralicheniformis)IMAULM4,于2026年1月19日保藏于中国微生物菌株保藏管理委员会普通微生物中心,保藏编号为CGMCC No.37453。其主要降解活性成分为热稳定性胞外酶;菌株安全性高,具备良好耐受性;在真实粮食基质中对黄曲霉毒素B1具有良好降解效果。
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