Monoclonal antibody against rsvn protein and preparation method and application thereof
By preparing a high-titer, stable monoclonal antibody against RSV N protein and applying it to a double-antibody sandwich ELISA detection method, the shortcomings of early screening for RSV infection were addressed, enabling rapid and highly specific detection and reducing the risk of severe cases.
CN122444864APending Publication Date: 2026-07-24LONGHU LAB
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Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- LONGHU LAB
- Filing Date
- 2026-06-03
- Publication Date
- 2026-07-24
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Figure CN122444864A_ABST
Abstract
The application provides a kind of anti-RSV N protein monoclonal antibody and its preparation method and application, belong to monoclonal antibody technical field.The heavy chain variable region amino acid sequence of the monoclonal antibody described in the application is as shown in SEQ ID NO.2, the light chain variable region amino acid sequence is as shown in SEQ ID NO.4, is secreted by hybridoma cell strain 1A2, subtype is IgG1, Kappa type, has high affinity and strong specificity to RSV N protein.The antibody can specifically recognize RSV N protein and inactivated RSV A type virus, has high titer, good stability, and can be used for preparing respiratory syncytial virus detection reagent, especially suitable for double antibody sandwich ELISA detection kit, provides core material for early rapid detection of RSV infection, has important clinical application value.
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