Guided bone regeneration composite barrier membrane based on reverse chiral topological deformation and temperature-sensitive shape memory and preparation method of guided bone regeneration composite barrier membrane
By using a barrier membrane made of anti-handed topological deformation and thermosensitive shape memory composite material, the problems of minimally invasive implantation, adaptive deformation and controllable degradation in GBR treatment have been solved, achieving efficient and safe bone regeneration treatment results.
Patent Information
- Application Number
- CN202610880646.6
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2026-06-17
- Publication Date
- 2026-07-28
AI Technical Summary
Existing GBR barrier membrane materials have problems such as the burden of secondary surgery, cumbersome operation, high risk of soft tissue exposure, insufficient mechanical properties and uncontrollable degradation in the treatment of large-area or severe vertical bone defects, making it difficult to achieve minimally invasive implantation, adaptive deformation and controllable degradation.
By employing anti-chiral topological deformation and temperature-sensitive shape memory composite materials, and through micro-nano impregnation technology and reverse thermodynamic programming, a composite barrier membrane consisting of a metal skeleton and a basement membrane layer is prepared. The metal skeleton is composed of staggered rings and connecting rods, and the basement membrane layer is a temperature-sensitive shape memory polymer, enabling minimally invasive implantation, self-expansion, nail-free anchoring, and full degradation.
It achieves minimally invasive surgery, adaptive three-dimensional support, sustained drug release, and controllable degradation, reducing surgical trauma, improving the stability and safety of the osteogenic environment, reducing the risk of infection, and avoiding secondary surgery and material exposure.