Airing cassette for immunofluorescence section

By designing a drying cassette for immunofluorescence slices, the problem of handheld fan blow-drying operation is solved, and the fluorescent slices are easily dried, improving operation convenience and stability.

CN223272264UActive Publication Date: 2025-08-26THE FIRST AFFILIATED HOSPITAL OF WANNAN MEDICAL COLLEGE (YIJISHAN HOSPITAL OF WANNAN MEDICAL COLLEGE)
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Patent Information

Application Number
CN202422349718.3
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-09-24
Publication Date
2025-08-26
Estimated Expiration
2034-09-24

AI Technical Summary

Technical Problem

In the prior art, a hand-held fan is required to perform blow-drying operations during the drying process of immunofluorescence sections, resulting in an increase in workload.

Method used

A drying cassette for immunofluorescence slices is designed. The lid is provided with a limit notch for placing a handheld fan and is equipped with a support structure. The support structure includes a U-shaped piece, and a partition and a partition groove are provided in the box for placing the slices for convenient drying.

Benefits of technology

It improves the convenience of the fluorescent slice drying process, reduces the operating needs of handheld fans, and improves the stability and efficiency of the drying process.

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Abstract

The utility model provides an air-drying cassette for immunofluorescence slices, which relates to the technical field of immunofluorescence experiment appliances, and comprises a box body and a box cover arranged on the box body, the box cover is provided with a limiting notch used for placing a handheld fan, the box cover is provided with a cover plate, and the cover plate is provided with a clamping groove used for clamping the handheld fan. The cover plate is detachably connected with the box cover through the limiting notches; a limiting notch is formed in the box cover, a supporting structure is arranged in the limiting notch, the supporting structure is used for supporting the handheld fan, and the limiting notch is formed in the box cover, so that the air outlet surface of the handheld fan is placed in the limiting notch in the process of fixing nail polish after the immunofluorescence slice is subjected to secondary antibody incubation patch and is dried; and the handheld fan in the limiting notch is supported by the supporting structure, so that the immunofluorescence section placed in the box body is conveniently dried in a dark place, the problem that in the prior art, the fluorescent section needs to be dried by a handheld fan is solved, and the convenience in the drying process of the fluorescent section is improved.
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Description

Technical Field

[0001] The utility model relates to immunofluorescence experimental appliance technology, in particular to a drying dark box for immunofluorescence slices. Background Art

[0002] Immunofluorescence is a powerful immunostaining technique that uses fluorescein-labeled antibodies to bind to target proteins and other molecules of interest for visualization using a microscope.

[0003] After immunofluorescence sections are incubated with primary and secondary antibodies and mounted, they need to be dried and fixed with nail polish. The stained fluorescent sections need to be dried while being protected from light to facilitate better observation under a confocal microscope. However, in the prior art, during the drying process, the fluorescent sections are often placed in a wet box on a glass slide and blown dry with a handheld fan, which increases the operator's workload. Utility Model Content

[0004] (1) Technical problems solved

[0005] In view of the shortcomings of the existing technology, the utility model provides a dark box for drying immunofluorescence sections, which solves the problem in the existing technology that a handheld fan is needed to dry the fluorescent sections.

[0006] (2) Technical solution

[0007] In order to achieve the above objectives, the present invention is implemented through the following technical solutions:

[0008] In the utility model, the drying cassette for immunofluorescence sections comprises a cassette body and a cassette cover mounted on the cassette body, wherein a limiting notch is provided on the cassette cover, wherein the limiting notch is used to place a handheld fan, and a cover plate is mounted on the cassette cover, wherein the cover plate is detachably connected to the cassette cover via the limiting notch;

[0009] A supporting structure is provided in the limiting notch, and the supporting structure is used for supporting the handheld fan.

[0010] Furthermore, the support structure includes a plurality of U-shaped members.

[0011] Furthermore, a plurality of partitions are provided inside the box body, and a plurality of first placement slots and a plurality of first separation slots are provided on the partitions. The first placement slots on the same partition are connected with the corresponding plurality of first separation slots, and the first placement slots on adjacent partitions correspond to each other one by one.

[0012] Furthermore, the positions of the first separation grooves on adjacent partitions correspond one to one.

[0013] Furthermore, a plurality of second placement grooves and a plurality of second separation grooves are provided on both inner side walls of the box body parallel to the partition, and the second placement grooves correspond one-to-one to the first placement grooves, and the second separation grooves correspond one-to-one to the first separation grooves.

[0014] Furthermore, a first connecting structure is installed on the box body, and a second connecting structure adapted to the first connecting structure is installed on the box cover.

[0015] Furthermore, the second connection structure includes a plurality of plug-in blocks, the first connection structure is provided with slots corresponding to the plug-in blocks one by one, and the box cover is plugged into the box body through the plurality of plug-in blocks and the plurality of slots.

[0016] (3) Beneficial effects

[0017] The utility model provides a drying cassette for immunofluorescence sections. Compared with the existing technology, it has the following advantages:

[0018] By opening a limiting slot on the box cover, the air outlet surface of the handheld fan is placed in the limiting slot during the drying process of the fluorescent slices, and the supporting structure is used to support the handheld fan in the limiting slot, thereby facilitating the drying operation of the fluorescent slices placed in the box body. This solves the problem in the prior art that a handheld fan is required to blow dry the fluorescent slices, and improves the convenience of the fluorescent slice drying process. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the following briefly introduces the drawings required for use in the embodiments or the description of the prior art. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying any creative work.

[0020] Figure 1 This is a diagram showing the usage of a drying cassette for immunofluorescence sections;

[0021] Figure 2 for Figure 1 A three-dimensional view of the middle box cover after opening the cover;

[0022] Figure 3 It is a three-dimensional diagram of the box body in the figure;

[0023] Figure 4 for Figure 3 Enlarged view of point A in the middle;

[0024] Figure 5 for Figure 3 Enlarged view of point B in the middle.

[0025] Reference numerals:

[0026] 10. Box body; 101. First connecting structure; 11. Partition; 111. First placement slot; 112. First dividing slot; 12. Second placement slot; 121. Second dividing slot; 20. Box cover; 201. Second connecting structure; 21. Cover plate; 22. Limiting notch; 221. Support structure. DETAILED DESCRIPTION

[0027] To make the purpose, technical solutions, and advantages of the embodiments of the present invention more clear, the technical solutions in the embodiments of the present invention are clearly and completely described. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making any creative efforts are within the scope of protection of the present invention.

[0028] The embodiment of the present application solves the problem in the prior art of needing a handheld fan to dry the fluorescent slices by providing a dark box for drying immunofluorescence slices, thereby achieving the convenience of drying the fluorescent slices.

[0029] The technical solution in the embodiments of the present application is to solve the above technical problems, and the overall idea is as follows:

[0030] like Figure 1-Figure 5 As shown, by opening a limiting slot on the box cover, the air outlet surface of the handheld fan is placed in the limiting slot during the drying process of the fluorescent slices, and the supporting structure is used to support the handheld fan in the limiting slot, thereby facilitating the drying operation of the fluorescent slices placed in the box body. This solves the problem in the prior art that a handheld fan is needed to blow dry the fluorescent slices, and improves the convenience of the fluorescent slice drying process.

[0031] In order to better understand the above technical solution, the above technical solution will be described in detail below with reference to the accompanying drawings and specific implementation methods.

[0032] like Figure 1-Figure 2 As shown, a dark box for drying immunofluorescence sections comprises a box body 10 and a box cover 20 mounted on the box body 10;

[0033] The box cover 20 is provided with a limiting notch 22, the limiting notch 22 is used to place the handheld fan, and the box cover 20 is mounted with a cover plate 21, the cover plate 21 is detachably connected to the box cover 20 through the limiting notch 22;

[0034] A support structure 221 is provided in the limiting notch 22 , and the support structure 221 is used to support the handheld fan.

[0035] By opening a limiting slot 22 on the box cover 20, during the drying process of the fluorescent slices, the air outlet surface of the handheld fan is placed in the limiting slot 22, and the support structure 221 is used to support the handheld fan in the limiting slot 22, thereby facilitating the drying operation of the fluorescent slices placed in the box body 10, solving the problem in the prior art that a handheld fan is needed to blow dry the fluorescent slices, and improving the convenience of the fluorescent slice drying process.

[0036] Specifically, when setting the limiting slot 22, the limiting slot 22 can be slightly smaller than the box cover 20, and a fan of corresponding size can be placed to facilitate the drying of the fluorescent slices in the dark box. A handheld fan can be a fan that can be completely placed in the limiting slot 22. Afterwards, the cover 21 can be covered or not covered according to the needs of use. The cover 21 is plugged into the box cover 20 through the limiting slot 22. According to specific needs, the sealing of the box body 10 during use is maintained to achieve sufficient light protection for the dark box.

[0037] like Figure 1-Figure 2 As shown, a first connection structure 101 is installed on the box body 10 , and a second connection structure 201 adapted to the first connection structure 101 is installed on the box cover 20 .

[0038] By providing the first connecting structure 101 and the second connecting structure 201 , the box cover 20 can be opened relative to the box body 10 , thereby facilitating the placement of fluorescent slices.

[0039] Specifically, the second connection structure 201 includes a plurality of plug-in blocks, the first connection structure 101 is provided with slots corresponding to the plug-in blocks, and the box cover 20 is plugged into the box body 10 through the plurality of plug-in blocks and the plurality of slots.

[0040] By setting the box cover 20 and the box body 10 to be plugged in through corresponding plug blocks and slots, the height of the box cover 20 relative to the box body 10 is controlled when the box cover 20 is in use, and then the height of the handheld fan and the fluorescent slices placed thereon is controlled. While the handheld fan is blowing air on the fluorescent slices, the human eye can observe the degree of drying of the fluorescent slices in a timely manner.

[0041] like Figure 2 As shown, the support structure 221 includes a plurality of U-shaped parts. By arranging the support structure 221 in the form of a plurality of U-shaped parts, support for the handheld fan is achieved. While maintaining the stability of the handheld fan after it is placed, the contact between the support structure 221 and the blowing surface of the handheld fan can be reduced, thereby facilitating the blowing operation of the handheld fan on the fluorescent slice and ensuring the fluidity of the handheld fan's blowing during the process of the handheld fan blowing the fluorescent slice.

[0042] like Figure 3-Figure 5As shown, a plurality of partitions 11 are provided inside the box body 10, and a plurality of first placement grooves 111 and a plurality of first separation grooves 112 are provided on the partitions 11. The first placement grooves 111 on the same partition 11 are connected with the corresponding plurality of first separation grooves 112, and the first placement grooves 111 on adjacent partitions 11 correspond one to one.

[0043] By setting up multiple first placement grooves 111, it is possible to facilitate the placement of fluorescent slices when drying, and by setting up multiple first separation grooves 112, it is possible to reduce the contact area between the fluorescent slices and the partition 11 when the fluorescent slices are placed in the first placement grooves 111, and reduce the impact of moisture on the top of the partition 11 on the side of the fluorescent slice close to the partition 11 when the fluorescent slices are drying.

[0044] The positions of the first dividing grooves 112 on adjacent partitions 11 correspond one to one. During use, the adjacent first dividing grooves 112 can facilitate the placement of glass slides. The glass slides are placed in the corresponding first dividing grooves 112 to achieve multifunctional use of the dark box.

[0045] The inner side walls of the box body 10 parallel to the partition 11 are provided with a plurality of second placement grooves 12 and a plurality of second separation grooves 121 . The second placement grooves 12 correspond one-to-one to the first placement grooves 111 , and the second separation grooves 121 correspond one-to-one to the first separation grooves 112 .

[0046] By opening multiple second placement grooves 12 on both side walls of the box body 10, when placing the fluorescent slice, one end of the fluorescent slice is located inside the second placement groove 12, and the side wall formed by the second placement groove 12 and the box body 10 is used to limit one end of the fluorescent slice, thereby improving the stability of the fluorescent slice during the drying process.

[0047] By opening a plurality of second dividing grooves 121 on both side walls of the box body 10 and utilizing the second dividing grooves 121 in combination with the corresponding first dividing grooves 112, the glass slides can be placed compactly inside the box body 10, thereby facilitating the placement of more glass slides inside the box body 10. The glass slides described here are fluorescent slices after being coated with fluorescence.

[0048] The lower ends of the first dividing groove 112 and the second dividing groove 121 are higher than the inner bottom wall of the box body 10, and the height of the lower ends of the first dividing groove 112 and the second dividing groove 121 above the inner bottom wall of the box body 10 is greater than 5 cm. When the glass slide is placed vertically in the first dividing groove 112 and the second dividing groove 121, the distance between the lower end of the glass slide and the lower end of the box body 10 is convenient for fingers to pass through, thereby facilitating the operation of taking the glass slide.

[0049] Specifically, the box body 10 , the first connecting structure 101 , the partition 11 , the first placement groove 111 , the first separation groove 112 , the second placement groove 12 and the second separation groove 121 are integrally formed.

[0050] When in use, the box cover 20 is pulled upwards, one end of the fluorescent slices to be dried is placed in the second placement slot 12, and the rest are placed in the corresponding first placement slot 111, then the air outlet surface of the handheld fan is placed inside the limiting slot 22, and the handheld fan is limited by the support structure 221 in the limiting slot 22, and the handheld fan is turned on to dry the fluorescent slices placed in the box body 10. It should be noted that the setting of the notch of the limiting slot 22 can meet the placement of the blowing surface of a conventional handheld fan and can realize the blowing demand of the handheld fan on the inside of the box body 10;

[0051] When the box body 10 is used as a slide storage box, the slides are placed vertically into the corresponding first dividing groove 112 and second dividing groove 121 to complete the placement of the slides, and the cover plate 21 is inserted into the limiting notch 22. The limiting notch 22 is closed by the cover plate 21, and the box cover 20 is controlled to close the box body 10, so that the slides can be stored after being placed in the box body 10, realizing the multifunctional use of the box body 10;

[0052] When setting up the dark box, a plurality of limiting slots 22 can be set according to actual needs, and corresponding fans can be placed in the limiting slots 22 to meet actual operation needs.

[0053] In summary, compared with the existing technology, the present invention has the following beneficial effects:

[0054] 1. By opening a limiting slot 22 on the box cover 20, during the drying process of the fluorescent slices, the air outlet surface of the handheld fan is placed in the limiting slot 22, and the support structure 221 is used to support the handheld fan in the limiting slot 22, thereby facilitating the drying operation of the fluorescent slices placed in the box body 10, solving the problem in the prior art that a handheld fan is required to blow dry the fluorescent slices, and improving the convenience of the fluorescent slice drying process.

[0055] 2. By setting the support structure 221 in the form of multiple U-shaped parts, support for the handheld fan is achieved. While maintaining the stability of the handheld fan after placement, the contact between the support structure 221 and the blowing surface of the handheld fan can be reduced, thereby facilitating the handheld fan's blowing operation on the fluorescent slices and ensuring the fluidity of the handheld fan's blowing during the process of the handheld fan blowing the fluorescent slices.

[0056] 3. By setting up multiple first placement grooves 111, it is possible to facilitate the placement of fluorescent slices when drying, and by setting up multiple first separation grooves 112, it is possible to reduce the contact area between the fluorescent slices and the partition 11 when the fluorescent slices are placed in the first placement grooves 111, and reduce the impact of moisture on the top of the partition 11 on the side of the fluorescent slice close to the partition 11 when the fluorescent slices are drying.

[0057] It should be noted that, in this document, relational terms such as first and second, etc., are used only to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply the existence of any such actual relationship or order between these entities or operations. Moreover, the terms "comprises," "comprising," or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article, or device comprising a series of elements includes not only those elements, but also other elements not explicitly listed, or elements inherent to such process, method, article, or device. In the absence of further limitations, an element defined by the phrase "comprising a ..." does not exclude the presence of other identical elements in the process, method, article, or device comprising the element.

[0058] The above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit the same. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that the technical solutions described in the aforementioned embodiments can still be modified, or some of the technical features thereof can be replaced by equivalents. However, these modifications or replacements do not deviate the essence of the corresponding technical solutions from the spirit and scope of the technical solutions of the various embodiments of the present invention.

Claims

1. A drying cassette for immunofluorescence sections, comprising a cassette body (10) and a cassette cover (20) mounted on the cassette body (10), characterized in that: A limiting notch (22) is provided on the box cover (20), and the limiting notch (22) is used to place a handheld fan. A cover plate (21) is installed on the box cover (20), and the cover plate (21) is detachably connected to the box cover (20) via the limiting notch (22); A support structure (221) is provided in the limiting notch (22), and the support structure (221) is used for supporting the handheld fan.

2. The immunofluorescence section drying cassette according to claim 1, characterized in that: The support structure (221) includes a plurality of U-shaped members.

3. The immunofluorescence section drying cassette according to claim 1, wherein: A plurality of partitions (11) are provided inside the box body (10), and a plurality of first placement grooves (111) and a plurality of first separation grooves (112) are provided on the partitions (11). The first placement grooves (111) on the same partition (11) are connected to the corresponding plurality of first separation grooves (112), and the first placement grooves (111) on adjacent partitions (11) correspond to each other one by one.

4. The immunofluorescence section drying cassette according to claim 3, characterized in that: The positions of the first separation grooves (112) on adjacent partitions (11) correspond one to one.

5. The immunofluorescence section drying cassette according to claim 4, characterized in that: A plurality of second placement grooves (12) and a plurality of second separation grooves (121) are provided on both inner side walls of the box body (10) and the partition (11), wherein the second placement grooves (12) correspond one-to-one to the first placement grooves (111), and the second separation grooves (121) correspond one-to-one to the first separation grooves (112).

6. The immunofluorescence section drying cassette according to claim 1, characterized in that: A first connection structure (101) is installed on the box body (10), and a second connection structure (201) adapted to the first connection structure (101) is installed on the box cover (20).

7. The immunofluorescence section drying cassette according to claim 6, characterized in that: The second connection structure (201) includes a plurality of plug-in blocks, and the first connection structure (101) is provided with slots corresponding to the plug-in blocks one by one, and the box cover (20) is plugged into the box body (10) via the plurality of plug-in blocks and the plurality of slots.