Clamp for fixing rabbit in pyrogen experiment

Abstract

The utility model relates to the technical field of medical experiment instruments, in particular to a clip for fixing a rabbit in a pyrogen experiment, which comprises a clip body, a fixing part and a clamping part are arranged on the clip body, the fixing part is used for fixing a pyrogen instrument probe, the clamping part is used for clamping the tail part of an experimental animal, the cross section of the clip body is U-shaped, and the clamping part is used for clamping the tail part of the experimental animal. The fixing part comprises a separation protrusion arranged on the inner side of the clip body, and a friction layer is arranged on the separation protrusion and the inner side wall of the U-shaped concave side of the clip body and used for wrapping the pyrogen instrument probe. The application has the effects of reducing the rabbit stress response and improving the accuracy of the body temperature detection result caused by the pyrogen reaction.

Description

Technical Field

[0001] The present application relates to the technical field of medical laboratory instruments, and in particular to a clip for fixing rabbits in pyrogen experiments. Background Art

[0002] Pyrogens are substances that, when injected into the body, can cause an abnormal rise in body temperature. In a broad sense, pyrogens include bacterial pyrogens, endogenous high-molecular-weight pyrogens, endogenous low-molecular-weight pyrogens, and chemical pyrogens.

[0003] Pyrogenic reaction refers to the clinical symptoms of chills, high fever, sweating, dizziness, vomiting, etc. that occur in patients during intravenous infusion of large amounts of fluids due to the presence of pyrogens in the liquid medicine. Rabbits are very sensitive to changes in body temperature and are very sensitive to many viruses and pathogens. They have the characteristic of being able to objectively reflect the fever caused by pyrogens in various drugs in the body. Through the pre-infection of rabbits, many anti-infective drugs can be studied, and then the changes in animal body temperature can be monitored through the pyrogen meter probe.

[0004] Chinese patent publication number CN101984933A discloses an experimental animal fixation device, including a platform with supporting legs, a hole through which the platform is penetrated from top to bottom, a detachable hanging rod on the front of the platform, and a fixator for fixing the animal on the back of the platform. The position of the fixator corresponds to the hole, and an elastic clip is also provided on the front of the platform.

[0005] In the process of measuring animal body temperature changes, the above technology requires the experimental animals to be fixed on the platform with elastic clips for experimental recording. Fixing the experimental animals on the platform for a long time will cause the experimental animals to have a stress response. The stress response will cause the temperature detection results caused by the experimental animals' pyrogenic reaction to be inaccurate, which has shortcomings. Utility Model Content

[0006] In order to reduce the influence of stress response on the pyrogen response results of animals, the present application provides a clip for fixing rabbits in pyrogen experiments.

[0007] The present application provides a clip for fixing rabbits in pyrogen experiments using the following technical solution:

[0008] A clip for fixing rabbits in pyrogen experiments comprises a clip body. The clip body is provided with a fixing part and a clamping part. The fixing part is used to fix a pyrogen meter probe, and the clamping part is used to clamp the tail of the experimental animal.

[0009] By adopting the above technical solution, the experimenter first fixes the pyrogen meter probe on the clip body through the fixing part, and then fixes the clip body to the tail of the experimental animal through the clamping part, so that the pyrogen meter probe can monitor the temperature changes of the experimental animal at all times. The experimental animal is in a free and relaxed state during the process of monitoring the temperature changes, which is more in line with the normal living state of the experimental animal, thereby reducing the experimental animal's stress and making the experimental results more accurate.

[0010] Optionally, the cross-section of the clip body is U-shaped, and the fixing portion includes a separation protrusion arranged on the inner side of the clip body. A friction layer is provided on the inner side wall of the separation protrusion and the U-shaped concave side of the clip body, and the friction layer is used to wrap the pyrometer probe.

[0011] By adopting the above technical solution, the U-shaped clip body clamps the pyrogen meter probe between the separating protrusion and the U-shaped concave side of the clip body through the elasticity of its material. At the same time, the friction layer increases the friction between the pyrogen meter probe and the clip body, reducing the possibility of the pyrogen meter probe accidentally falling off during the movement of the experimental animal.

[0012] Optionally, a flexible layer is provided on the inner side wall of the open end of the clip body, and the flexible layer is located on the side of the separation protrusion facing away from the friction layer.

[0013] By adopting the above technical solution, when the clip body is clamped on the tail of the experimental animal, the flexible layer is squeezed and deformed and fits the tail of the experimental animal, thereby reducing the discomfort of the experimental animal's tail and increasing the stability of clamping, so that the clip body can be firmly clamped on the tail of the experimental animal.

[0014] Optionally, the clamping portion includes a clamping piece provided on the clip body and having an L-shaped cross section, a flexible layer is also provided on the inner side of the clamping piece, a rough layer is provided on the flexible layer, and the rough layer is used to contact the tail of the experimental animal.

[0015] By adopting the above technical solution, the L-shaped clamping piece can provide good wrapping and stability for the animal's tail, and can adapt to the tails of experimental animals of different sizes. At the same time, the rough layer increases the friction between the clip body and the experimental animal, so that the clip body can be better fixed on the tail of the experimental animal.

[0016] Optionally, the clamping portion includes a clamping plate rotatably arranged on the clip body, a flexible layer is also provided on the inner side of the clamping plate, an anti-stripping layer is provided on the flexible layer, the anti-stripping layer is used to contact the tail of the experimental animal, and a torsion spring is provided between the clamping plate and the clip body.

[0017] By adopting the above technical solution, the experimenter rotates the clamping plate, the torsion spring is deformed, and then the tail of the experimental animal is placed between the clamping plate and the clip body for clamping. The flexible layer is deformed and fits the tail of the experimental animal, while reducing the impact on the fixation stability of the pyrogen meter probe, and the anti-detachment layer is conducive to improving the stability of the clip body fixed to the tail of the experimental animal.

[0018] Optionally, a pressure plate is provided on the clamping plate, and an anti-slip strip is provided on the pressure plate.

[0019] By adopting the above technical solution, the experimenter presses the pressure plate, and the pressure plate drives the clamping plate to rotate, which makes it easier for the experimenter to open the clamping plate. At the same time, the anti-slip strip reduces the possibility of the experimenter's hand accidentally falling off the pressure plate and causing the clamping plate to pinch the tail of the experimental animal, which is beneficial to reducing the stress response of the experimental animal.

[0020] Optionally, the cross section of the clamping plate is L-shaped, and one end of the clamping plate facing away from the rotation center thereof abuts against the clip body.

[0021] By adopting the above technical solution, the possibility of the clamping plate excessively squeezing the tail of the experimental animal and causing discomfort to the experimental animal is reduced. At the same time, the L-shaped clamping plate can provide good wrapping and stability for the animal's tail.

[0022] Optionally, a card slot is provided on the clip body and located at the separation protrusion, a card pin is inserted into the card slot of the clip body, and the cross section of the card pin is U-shaped.

[0023] By adopting the above technical solution, the possibility of plastic deformation of the U-shaped concave side of the clamp body due to frequent use, which in turn causes the clamp body to fail in clamping the pyrogen analyzer probe, is reduced, which is conducive to the stability of the clamping state of the pyrogen analyzer probe.

[0024] In summary, this application includes at least one of the following beneficial technical effects:

[0025] 1. The experimenter first fixes the pyrogen meter probe on the clip body through the fixing part, and then fixes the clip body to the tail of the experimental animal through the clamping part, so that the pyrogen meter probe can monitor the temperature change of the experimental animal at all times. The experimental animal is in a free and relaxed state during the process of monitoring the temperature change, which is more in line with the normal life state of the experimental animal, thereby reducing the experimental animal's experimental animal stress and making the experimental results more accurate;

[0026] 2. The U-shaped clip body, through its material elasticity, clamps the pyrogen meter probe between the separation protrusion and the U-shaped concave side of the clip body. At the same time, the friction layer increases the friction between the pyrogen meter probe and the clip body, reducing the possibility of the pyrogen meter probe accidentally falling off during the movement of the experimental animal;

[0027] 3. The experimenter rotates the clamping plate, the torsion spring is deformed, and then the tail of the experimental animal is placed between the clamping plate and the clip body for clamping. The flexible layer is deformed and fits the tail of the experimental animal, while reducing the impact on the fixation stability of the pyrogen analyzer probe. The anti-stripping layer is conducive to improving the stability of the clip body fixed to the tail of the experimental animal. BRIEF DESCRIPTION OF THE DRAWINGS

[0028] Figure 1 It is a structural diagram of Example 1 of the present application.

[0029] Figure 2 It is a structural diagram of the positional relationship among the clamping plate, the anti-stripping layer and the pressure plate in Example 2 of the present application.

[0030] Figure 3 It is a structural diagram of the positional relationship among the anti-slip strip, the latch and the pressure plate in Example 3 of the present application.

[0031] Explanation of the accompanying reference numerals: 1. Pyrogen analyzer probe; 2. Clip body; 3. Fixing portion; 31. Separation protrusion; 32. Friction layer; 4. Clamping portion; 41. Clamping piece; 42. Rough layer; 43. Clamping plate; 44. Anti-slip layer; 45. Torsion spring; 5. Flexible layer; 6. Pressure plate; 7. Anti-slip strip; 8. Slot; 9. Pin. DETAILED DESCRIPTION

[0032] The following is combined with Figure 1-Figure 3 This application is described in further detail.

[0033] The embodiment of the present application discloses a clip for fixing rabbits in pyrogen experiments.

[0034] Example 1

[0035] Reference Figure 1 A clip for fixing rabbits in pyrogen experiments includes a clip body 2 with a U-shaped cross-section. The clip body 2 is made of plastic material, is light in weight, causes little discomfort to the experimental animals, and is not easy to fall off. A fixing part 3 and a clamping part 4 are arranged on the clip body 2. The fixing part 3 is used to fix the pyrogen meter probe 1, and the clamping part 4 is used to clamp the tail of the experimental animal.

[0036] Reference Figure 1 The fixing portion 3 includes two separating protrusions 31 integrally formed on the inner side of the U-shaped portion of the clip body 2. A friction layer 32 is bonded to the inner side wall of the separating protrusion 31 and the U-shaped concave side of the clip body 2. The cross-section of the friction layer 32 is C-shaped. The friction layer 32 is used to wrap the pyrometer probe 1. A flexible layer 5 is bonded to the inner side wall of the open end of the clip body 2. The flexible layer 5 and the friction layer 32 are both made of polyurethane rigid foam material. The polyurethane rigid foam can be compressed and is easy to clean and dry.

[0037] Reference Figure 1 The flexible layer 5 is located on the side of the separating protrusion 31 facing away from the friction layer 32. The clamping portion 4 includes a clamping piece 41 integrally formed on the clip body 2 and having an L-shaped cross-section. The clamping piece 41 abuts against the clip body 2. The flexible layer 5 is also bonded to the inner side of the clamping piece 41. The rough layer 42 is bonded to the flexible layer 5. The rough layer 42 is used to contact the tail of the experimental animal.

[0038] The implementation principle of Example 1 is: the experimenter first bends the U-shaped open end of the clip body 2, and the U-shaped concave side of the clip body 2 is deformed, and then places the pyrogen meter probe 1 on the U-shaped concave side of the clip body 2, and then loosens the U-shaped ends of the clip body 2, and the U-shaped concave side of the clip body 2 recovers the deformation and presses the friction layer 32 onto the pyrogen meter probe 1.

[0039] The experimenter then bends the clamping piece 41, and then puts the U-shaped end of the clip body 2 on the tail of the experimental animal. The experimental animal here can be a rabbit. Then the clamping piece 41 is released, and the flexible layer 5 is squeezed against the tail of the experimental animal and deformed. The flexible layer 5 deforms and fits the tail of the experimental animal. At the same time, the rough layer 42 increases the friction between the clip body 2 and the tail of the experimental animal, so that the clip body 2 is firmly fixed to the tail of the experimental animal, thereby reducing the stress response of the experimental animal.

[0040] Example 2

[0041] refer to Figure 2 The difference between this embodiment and embodiment 1 is that the clamping portion 4 includes a clamping plate 43 that is rotatably connected to the clip body 2 and has an L-shaped cross-section. The end of the clamping plate 43 facing away from its rotation center abuts against the clip body 2. A flexible layer 5 is also bonded to the inner side of the clamping plate 43, and an anti-stripping layer 44 is bonded to the flexible layer 5.

[0042] refer to Figure 2 The anti-stripping layer 44 can be made of double-sided tape, and the anti-stripping layer 44 is used to bond with the tail of the experimental animal. A torsion spring 45 is arranged at the rotation point between the clamping plate 43 and the clip body 2. A pressure plate 6 is integrally formed on the clamping plate 43, and an anti-slip strip 7 is integrally formed on the pressure plate 6.

[0043] The implementation principle of Example 2 is: the experimenter presses the pressure plate 6, the pressure plate 6 drives the clamping plate 43 to rotate around its axis, and the torsion spring 45 is deformed, which makes it convenient for the experimenter to quickly fix the clip body 2 on the tail of the experimental animal. At the same time, the anti-peeling layer 44 increases the bonding force between the clip body 2 and the tail hair of the experimental animal.

[0044] Example 3

[0045] refer to Figure 3The difference between this embodiment and embodiment 2 is that a card slot 8 is provided on the outer wall of the clip body 2 and located at the separation protrusion 31, and a card pin 9 with a U-shaped cross section is inserted into the card slot 8 of the clip body 2, and the card pin 9 is made of plastic material.

[0046] The implementation principle of Example 3 is as follows: when the U-shaped concave side of the clip body 2 undergoes plastic deformation due to frequent bending, the bayonet pin 9 can improve the stability of the clip body 2 in clamping the pyrometer probe 1.

[0047] The above are all preferred embodiments of the present application, and are not intended to limit the scope of protection of the present application. Therefore, any equivalent changes made based on the structure, shape, and principle of the present application should be included in the scope of protection of the present application.

Claims

1. A clip for fixing rabbits in pyrogen experiments, characterized by: The clamp body (2) comprises a fixing portion (3) and a clamping portion (4), wherein the fixing portion (3) is used to fix the pyrogen analyzer probe (1), and the clamping portion (4) is used to clamp the tail of the experimental animal.

2. The clip for fixing rabbits in pyrogen experiments according to claim 1, characterized in that: The cross section of the clip body (2) is U-shaped, and the fixing portion (3) includes a separation protrusion (31) arranged on the inner side of the clip body (2). A friction layer (32) is provided on the inner side wall of the separation protrusion (31) and the U-shaped concave side of the clip body (2), and the friction layer (32) is used to wrap the pyrometer probe (1).

3. The clip for fixing rabbits in pyrogen experiments according to claim 2, characterized in that: A flexible layer (5) is provided on the inner side wall of the open end of the clip body (2), and the flexible layer (5) is located on the side of the separation protrusion (31) facing away from the friction layer (32).

4. The clip for fixing rabbits in pyrogen experiments according to claim 3, characterized in that: The clamping portion (4) includes a clamping piece (41) provided on the clip body (2) and having an L-shaped cross section. A flexible layer (5) is also provided on the inner side of the clamping piece (41). A rough layer (42) is provided on the flexible layer (5). The rough layer (42) is used to contact the tail of the experimental animal.

5. The clip for fixing rabbits in pyrogen experiments according to claim 3, characterized in that: The clamping portion (4) includes a clamping plate (43) rotatably arranged on the clamp body (2), a flexible layer (5) is also arranged on the inner side of the clamping plate (43), an anti-stripping layer (44) is arranged on the flexible layer (5), and the anti-stripping layer (44) is used to contact the tail of the experimental animal, and a torsion spring (45) is arranged between the clamping plate (43) and the clamp body (2).

6. The clip for fixing rabbits in pyrogen experiments according to claim 5, characterized in that: A pressing plate (6) is provided on the clamping plate (43), and an anti-slip strip (7) is provided on the pressing plate (6).

7. The clip for fixing rabbits in pyrogen experiments according to claim 5, characterized in that: The cross section of the clamping plate (43) is L-shaped, and one end of the clamping plate (43) facing away from its rotation center abuts against the clamp body (2).

8. The clip for fixing rabbits in pyrogen experiments according to claim 5, characterized in that: A card slot (8) is provided on the clip body (2) at the separation protrusion (31), and a card pin (9) is inserted into the card slot (8) of the clip body (2), wherein the cross section of the card pin (9) is U-shaped.

Images