High-temperature and PM2.5 combined exposure cabin

Abstract

The utility model relates to a high temperature and PM2.5 combined exposure cabin, and relates to the technical field of exposure experiment devices, the high temperature and PM2.5 combined exposure cabin comprises a cabin body, a plurality of cages are uniformly arranged in the cabin body along the height direction at intervals, and the plurality of cages are distributed in a step shape; an air inlet located above the cage at the second top layer is formed in the top of the cabin body, and the top of the cabin body inclines downwards from the air inlet to one side of the cage at the topmost layer; an air outlet located below the cage at the second bottom layer is formed in the bottom of the cabin body, and the bottom of the cabin body inclines upwards from the air outlet to one side of the cage at the bottommost layer; heating pastes are arranged on the two side walls of the cabin body, and temperature probes are arranged at the top, the middle and the bottom in the cabin body. The utility model provides the exposure device capable of performing the high-temperature and PM2.5 combined exposure experiment, and the requirements of the high-temperature and PM2.5 combined exposure experiment are met.

Description

Technical Field

[0001] The present invention relates to the field of exposure experimental devices, in particular to a high temperature and PM 2.5 Joint Exposure Chamber. Background Art

[0002] Atmospheric particulate matter (PM 2.5 ) is the main factor causing air pollution. Long-term exposure to high concentrations of PM 2.5 The environment will bring great risks to human health. In addition, when the exposure temperature is high, it will enhance the PM 2.5 Effects on total mortality and cardiovascular disease mortality, and multiple epidemiological evidence has shown that high temperature and PM 2.5 Combined exposure can have negative effects.

[0003] In China, high temperatures and PM 2.5 Combined exposure was significantly associated with increased myocardial infarction (MI) mortality, especially in the elderly and female groups. 2.5 The synergistic effect leads to MI deaths, but cold waves do not. For pregnant women, the study found that exposure to heat waves in late pregnancy can trigger premature births, and found that moderate intensity heat waves are associated with PM 2.5 The effects of exposure on preterm birth were synergistic.

[0004] The above epidemiological studies have confirmed the relationship between high temperature and PM 2.5 There are currently no laboratory studies on the adverse effects of combined exposure to high temperatures and PM. 2.5 Combined exposure experimental device, based on the above background, this patent intends to provide a device that can conduct high temperature and PM 2.5 Exposure apparatus for combined exposure experiments. Utility Model Content

[0005] In view of the above problems, the present application is proposed to provide a high temperature and PM2.5 system that overcomes the above problems or at least partially solves the above problems. 2.5 Joint Exposure Chamber.

[0006] This application provides a high temperature and PM 2.5 The joint exposure chamber adopts the following technical solutions:

[0007] A high temperature and PM 2.5 The combined exposure cabin comprises a cabin body, wherein a plurality of cages are evenly spaced along the height direction of the cabin body, and the plurality of cages are distributed in a stepped manner;

[0008] The top of the cabin is provided with an air inlet located above the cage at the second top layer, and the top of the cabin is inclined downward from the air inlet to the side of the cage at the top layer;

[0009] The bottom of the cabin is provided with an air outlet located below the cage at the second bottom layer, and the bottom of the cabin is inclined upward from the air outlet to the side of the cage at the bottom layer;

[0010] Heating patches are provided on both side walls of the cabin, and temperature probes are provided at the top, middle and bottom of the cabin.

[0011] Optionally, slides are provided on both sides of the top of the cage along its length, and a plurality of pulleys are evenly provided on the slides along its length, and slide rails for the pulleys to roll and slide are provided on the inner side wall of the cabin.

[0012] Optionally, a concave baffle is further provided in the cabin and is located below the cage, and the area of ​​the concave baffle is larger than the area of ​​the cage.

[0013] Optionally, mounting bars are extended on both sides of the concave baffle, and support bars for supporting the mounting bars are provided on the inner side wall of the cabin.

[0014] Optionally, the concave baffle extends upward relative to one end of the cabin door, and when the cage is installed, the bottom of the cage collides with the upwardly extending end of the concave baffle, and the pulley collides with the slide rail.

[0015] Optionally, the heating patch includes multiple heating support patches.

[0016] Optionally, both side walls of the cabin are provided with a plurality of groups of sampling ports along the height direction thereof, and the plurality of groups of sampling ports are distributed in a stepped manner and are arranged corresponding to the cage.

[0017] In summary, this application provides a method for high temperature and PM 2.5 The exposure device of the combined exposure experiment meets the requirements of high temperature and PM 2.5 The need for combined exposure experiments. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 It is a schematic diagram of the overall structure of an embodiment of the present application;

[0019] Figure 2 This is a schematic diagram of the internal structure of the cabin in an embodiment of the present application;

[0020] Figure 3 This is a schematic diagram of the connection between the cabin and the cage in the embodiment of the present application;

[0021] Figure 4yes Figure 3 A partial enlarged schematic diagram of area A in the middle;

[0022] Figure 5 yes Figure 3 A partial enlarged schematic diagram of area B in the middle.

[0023] Explanation of the accompanying reference numerals: 1. Cabin; 11. Air inlet; 12. Air outlet; 13. Slide rail; 14. Support bar; 15. Sampling port; 2. Cage; 21. Slide; 3. Concave baffle; 31. Mounting bar; 4. Heating sticker; 41. Heating support sticker. DETAILED DESCRIPTION

[0024] To make the objectives, technical solutions, and advantages of the present invention more clear, the technical solutions of the present invention will be clearly and completely described below in conjunction with the accompanying drawings of the embodiments of the present invention. Obviously, the described embodiment is only one embodiment of the present invention, not all embodiments. Based on the described embodiment of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0025] Unless otherwise defined, technical or scientific terms used in the present invention shall have the same meaning as commonly understood by one of ordinary skill in the art to which the present invention belongs.

[0026] This embodiment provides a high temperature and PM 2.5 Joint Exposure Chamber.

[0027] Reference Figure 1 、 Figure 2 , a high temperature and PM 2.5 The combined exposure chamber comprises a chamber body 1 and a plurality of cages 2 arranged in the chamber body 1 .

[0028] An air inlet 11 and an air outlet 12 are respectively connected to the top and bottom of the cabin body 1 , and a plurality of cages 2 are evenly spaced along the height direction of the cabin body 1 and distributed in a stepped manner.

[0029] The air inlet 11 is arranged above the second-top cage 2, and the top of the cabin 1 is tilted downward from the air inlet 11 to the side of the top-most cage 2; the air outlet 12 is arranged below the second-bottom cage 2, and the bottom of the cabin 1 is tilted upward from the air outlet 12 to the side of the bottom-most cage 2, so as to ensure the uniformity of the aerosol circulation in the cabin 1, and thus ensure the uniformity of the exposure of the experimental animals.

[0030] Reference Figure 3 、 Figure 4In order to facilitate the installation and disassembly of the cage 2, slides 21 are provided on both sides of the top of the cage 2 along its length, and a plurality of pulleys (not shown in the figure) are evenly provided on the slide 21 along its length, and a slide rail 13 for the pulleys to roll and slide is provided on the inner wall of the cabin 1.

[0031] Reference Figure 3 、 Figure 4 In order to effectively collect the excrement of experimental animals, a concave baffle 3 is horizontally arranged under each cage 2, and the area of ​​the concave baffle 3 is larger than the area of ​​the cage 2; at the same time, mounting strips 31 are extended on both sides of the concave baffle 3, and a support strip 14 for supporting the mounting strip 31 is provided on the inner side wall of the cabin body 1, so as to realize the convenient disassembly and installation of the concave baffle 3.

[0032] In order to further improve the convenience of installing and disassembling the cage 2, the concave baffle 3 is extended upward at one end relative to the hatch of the cabin body 1; when the cage 2 is installed, the bottom of the cage 2 contacts the upwardly extending end of the concave baffle 3, and the pulley contacts the upper end surface of the slide rail 13 to support the cage 2, which is convenient for the installation of the cage 2; similarly, when the cage 2 is disassembled, the bottom of the cage 2 also contacts the upwardly extending end of the concave baffle 3 and supports the cage 2, which is convenient for the disassembly of the cage 2.

[0033] Reference Figure 1 , high temperature and PM 2.5 The combined exposure chamber also includes heating stickers 4 arranged on both side walls of the chamber body 1. The heating stickers 4 are used to heat the chamber body 1 to create a high temperature environment required for the high temperature exposure experiment.

[0034] Since hot air will flow toward the top of the cabin 1 during the heating process, in order to ensure uniform temperature within the cabin 1, the heating patch 4 may include multiple heating patches 41. The multiple heating patches 41 can work independently, and the heating power of the heating patch 41 located above the cabin 1 is less than the heating power of the heating patch 41 located in the middle of the cabin 1 and less than the heating power of the heating patch 41 located below the cabin 1. In the specific implementation process, two heating patches 4 are arranged side by side on each side of the cabin 1. Each heating patch 4 is preferably composed of three heating patches 41, and the three heating patches 41 are arranged side by side in the vertical direction. The area of ​​the heating patch 41 located in the middle of the cabin 1 is larger than the area of ​​the heating patch 41 located above or below the cabin 1.

[0035] In order to facilitate the monitoring of temperature changes at different locations in the cabin 1, temperature probes (not shown in the figure) can be set at the top, middle and bottom positions of the cabin 1, so as to adjust the heating power of the heating supports 41 at the corresponding positions according to the temperature changes during the experiment, thereby further ensuring the uniformity of the temperature in the cabin 1 during the experiment.

[0036] Reference Figure 1 Both side walls of the cabin 1 are evenly spaced along its height direction with multiple groups of sampling ports 15. The multiple groups of sampling ports 15 are distributed in a stepped manner and are arranged corresponding to the cage 2, so as to sample and detect the aerosol exposure status of the cage 2 at the corresponding position during the experiment.

[0037] The above are all preferred embodiments of the present application, and are not intended to limit the scope of protection of the present application. Therefore, any equivalent changes made based on the structure, shape, and principle of the present application should be included in the scope of protection of the present application.

Claims

1. High temperature and PM 2.5 The combined exposure chamber is characterized by: It comprises a cabin (1), wherein a plurality of cages (2) are evenly spaced inside the cabin (1) along its height direction, and the plurality of cages (2) are distributed in a stepped manner; The top of the cabin (1) is provided with an air inlet (11) located above the cage (2) at the second top layer, and the top of the cabin (1) is tilted downward from the air inlet (11) toward the cage (2) at the top layer; The bottom of the cabin (1) is provided with an air outlet (12) located below the cage (2) at the second bottom layer, and the bottom of the cabin (1) is inclined upward from the air outlet (12) toward the cage (2) at the bottom layer; Heating stickers (4) are provided on both side walls of the cabin (1), and temperature probes are provided at the top, middle and bottom of the cabin (1).

2. A high temperature and PM according to claim 1 2.5 The combined exposure chamber is characterized by: Slides (21) are provided on both sides of the top of the cage (2) along its length direction, and a plurality of pulleys are evenly provided on the slides (21) along its length direction, and slide rails (13) for the pulleys to roll and slide are provided on the inner side wall of the cabin (1).

3. A high temperature and PM according to claim 2 2.5 The combined exposure chamber is characterized by: A concave baffle (3) is also provided in the cabin (1) and is located below the cage (2), and the area of ​​the concave baffle (3) is larger than the area of ​​the cage (2).

4. A high temperature and PM according to claim 3 2.5 The combined exposure chamber is characterized by: Mounting strips (31) are extended on both sides of the concave baffle (3), and support strips (14) for carrying the mounting strips (31) are provided on the inner side wall of the cabin (1).

5. A high temperature and PM according to claim 3 2.5 The combined exposure chamber is characterized by: The concave baffle (3) extends upward relative to one end of the cabin door of the cabin body (1), and when the cage (2) is installed, the bottom of the cage (2) contacts the upwardly extending end of the concave baffle (3), and the pulley contacts the slide rail (13).

6. A high temperature and PM according to claim 1 2.5 The combined exposure chamber is characterized by: The heating patch (4) comprises a plurality of heating support patches (41).

7. A high temperature and PM according to claim 1 2.5 The combined exposure chamber is characterized by: Both side walls of the cabin (1) are provided with multiple groups of sampling ports (15) along the height direction thereof, and the multiple groups of sampling ports (15) are distributed in a stepped manner and are arranged corresponding to the cage (2).

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