Darkroom imaging device

Abstract

The utility model provides darkroom imaging equipment, which comprises a box body and an imaging module, the box body is provided with a darkroom space, the imaging module is arranged in the box body and is used for imaging a blotting membrane in the darkroom space, the box body is provided with an upper cover, a base and a cover closing detection device, and the upper cover can be opened and closed relative to the base. And the cover closing detection device is arranged on at least one of the base and the upper cover and is used for detecting whether the upper cover is closed or not. Whether the upper cover is closed or not is detected through the cover closing detection device, and the possibility that the upper cover is not closed tightly can be reduced.

Description

Technical Field

[0001] The present application relates to an imaging instrument, and in particular to a darkroom imaging device. Background Art

[0002] When imaging targets with weak optical signals (such as proteins), a darkroom environment is often required to minimize interference from external stray light. However, some current darkroom imaging equipment may not close tightly when creating a darkroom environment, resulting in light leakage and other problems. Utility Model Content

[0003] The present application provides a darkroom imaging device, which includes a housing and an imaging module. The housing has a darkroom space. The imaging module is arranged in the housing and is used to image the blot film in the darkroom space. The housing has an upper cover, a base and a closed cover detection device. The upper cover can be opened and closed relative to the base and, when closed, blocks external light from entering the darkroom space. The closed cover detection device is arranged on at least one of the base and the upper cover and is used to detect whether the upper cover is closed.

[0004] In this utility model, when the top cover is open relative to the base, the user can place the blotting membrane into the darkroom space, then close the top cover to block external light from entering the darkroom space and start imaging. In addition, the lid closure detection device detects whether the top cover is closed, thereby reducing the possibility of problems such as the top cover not being closed tightly. BRIEF DESCRIPTION OF THE DRAWINGS

[0005] Figure 1 is a schematic structural diagram of a darkroom imaging device according to one or more embodiments;

[0006] Figure 2 for Figure 1 Schematic diagram of the section along AA;

[0007] Figure 3 is a schematic structural diagram of a sealing member according to one or more embodiments;

[0008] Figure 4 is a schematic diagram of the assembly relationship of a sealing member according to one or more embodiments;

[0009] Figure 5 is a schematic structural diagram of a light shielding member according to one or more embodiments;

[0010] Figure 6 for Figure 5 Schematic diagram of the cross section along BB.

[0011] Description of the accompanying drawings:

[0012] Darkroom imaging equipment 1,

[0013] Box body 10, darkroom space 100, upper cover 11, base 12, top wall 121, hollow area 122, black light-absorbing layer 123, limiting groove 124, closed cover detection device 13, magnetic induction switch 131, marker 132, interactive device 14, light-emitting component 141, sealing member 15, limiting protrusion 151, light shielding member 16, first step surface 161, second step surface 162, first groove 163, second groove 164, matching structure 17, third step surface 171, fourth step surface 172, first light-blocking ring 173, second light-blocking ring 174,

[0014] Imaging module 20 , carrier 21 , mounting slot 210 , photosensitive chip 22 . DETAILED DESCRIPTION

[0015] The present application will be further described below with reference to the accompanying drawings and some embodiments. The following embodiments are mainly used to illustrate the technical solutions of the present application, and therefore cannot be used to limit the scope of protection of the present application.

[0016] Unless otherwise defined, the technical and scientific terms used herein have the same meanings as those commonly understood by technicians in the technical field to which this application belongs; the terms used herein are mainly used to describe specific embodiments and are not intended to limit this application; the terms "include", "have", "comprise" and other synonyms with the same or similar meanings in the specification and claims of this application and the above-mentioned figure descriptions are intended to cover non-exclusive inclusions.

[0017] In the description of the embodiments of this application, the technical terms "first" and "second" are primarily used to distinguish different objects and should not be understood as explicitly or implicitly indicating relative importance or implicitly indicating the number, specific order, or primary and secondary relationship of the indicated technical features. In the description of the embodiments of this application, the meaning of "plurality" is more than two, unless otherwise specifically defined.

[0018] In this document, the specific features, structures, or characteristics described in any embodiment may be included in at least one embodiment of the present application or a combination of at least two embodiments. It will be understood by those skilled in the art that the embodiments described herein may be combined with other embodiments in this document or other embodiments outside of this document.

[0019] In the description of the embodiments of the present application, technical terms used to indicate orientation or positional relationships, such as "center", "longitudinal", "lateral", "length", "width", "thickness", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "clockwise", "counterclockwise", "axial", "radial", "circumferential", etc., are mainly used to facilitate the description of the embodiments of the present application and simplify the description, and are not considered to mean that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as a limitation on the present application.

[0020] In the various embodiments of this application, unless otherwise expressly specified or limited, technical terms such as "set," "install," "assemble," "connect," "connect," and "fix" should be understood broadly. For example, connection can include fixed connection, detachable connection, or integral molding; it can also include at least one of mechanical connection and electrical connection; and it can include direct connection or indirect connection through an intermediate medium. Those skilled in the art will understand the specific meanings of the above terms in the embodiments of this application based on the specific circumstances.

[0021] See also Figure 1 and Figure 2 The darkroom imaging device 1 may include a housing 10 and an imaging module 20. The housing 10 has a darkroom space 100. The imaging module 20 is arranged in the housing 10 and is used to image the blot film in the darkroom space 100. The housing 10 has an upper cover 11 and a base 12. The upper cover 11 can be opened and closed relative to the base 12, and when closed, it blocks external light from entering the darkroom space 100. For example, the upper cover 11 can be hinged to the base 12. Furthermore, the imaging module 20 can perform close-range imaging of the blot film placed on the surface of the photosensitive area of ​​the imaging module 20.

[0022] The blotting membrane is typically prepared by separating proteins by electrophoresis and subsequently transferring them to a solid-phase carrier (e.g., NC membrane or PVDF membrane). Proteins are typically labeled with dyes (e.g., chemiluminescent dyes or fluorescent dyes). Chemiluminescent dyes produce chemiluminescent signals, while fluorescent dyes produce fluorescent signals under the influence of corresponding excitation light. The blotting membrane is placed in a darkroom 100, and the optical signal (e.g., chemiluminescent or fluorescent signal) is detected to analyze the protein (e.g., location, concentration, etc.).

[0023] Also, see Figure 2The box body 10 may further include a lid-closing detection device 13, which is provided on at least one of the base 12 and the upper cover 11, and is used to detect whether the upper cover 11 is closed. Optionally, the lid-closing detection device 13 includes a marker 132 (such as a magnet or ferromagnet, a magnetic element, etc.) provided on the upper cover 11 and a magnetic induction switch 131 provided on the base 12, so as to apply a force to the upper cover 11 toward the base 12. In this case, when the upper cover 11 is not tightly closed, the upper cover 11 can be closed by magnetic force. Of course, in other embodiments, the lid-closing detection device 13 may also include an infrared sensor switch or a photoelectric sensor switch, and the corresponding marker 132 can be adaptively adjusted.

[0024] In the present invention, when the upper cover 11 is open relative to the base 12, the user can place the blotting membrane into the darkroom space 100, then close the upper cover 11 to block external light from entering the darkroom space 100 and begin imaging. Furthermore, the cover closure detection device 13 detects whether the upper cover 11 is closed, thereby reducing the possibility of problems such as the upper cover 11 not being tightly closed.

[0025] See also Figure 1 Darkroom imaging device 1 may further include a processing circuit (not shown) and an interaction device 14. The processing circuit is coupled to lid closure detection device 13 and interaction device 14 and is configured to output a warning signal when lid closure detection device 13 detects that upper cover 11 is not closed. Interaction device 14 may include a display screen or a light-emitting component 141.

[0026] For example, the interactive device 14 includes a light-emitting assembly 141. Light-emitting assembly 141 can be located on the upper cover 11 or the base 12. Light-emitting assembly 141 can be a light bar that emits two colors. In this case, different colors can be used to interact with the user. Alternatively, light-emitting assembly 141 can have at least two lighting modes. For example, light-emitting assembly 141 can include multiple LED lights that can be independently turned on or off. In this case, different combinations of LED lights can be used to interact with the user.

[0027] See also Figure 2 The base 12 has a top wall 121. The top wall 121 has a hollow area 122. The imaging module 20 is located below the hollow area 122 and connected to the top wall 121. When the hollow area 122 is enclosed by the imaging module 20 and the upper cover 11, the darkroom space 100 described above can be formed. The side wall surface of the hollow area 122 has a black light absorbing layer 123 (see Figure 4 The black light-absorbing layer 123 can be black to reduce light reflection and the risk of optical signal contamination. Optionally, the black light-absorbing layer 123 can be a black coating applied to the sidewalls of the hollow region 122, or can be formed by surface treatment (e.g., oxidation) of the sidewalls of the hollow region 122.

[0028] See also Figure 2 , the imaging module 20 includes a carrier 21 and a photosensitive chip 22. The carrier 21 has a mounting groove 210, and the photosensitive chip 22 is arranged in the mounting groove 210. The carrier 21 can be made of metal (such as aluminum or aluminum alloy) to facilitate heat dissipation of the photosensitive chip 22. The carrier 21 is fixed to the top wall 121 so that the photosensitive chip 22 is located below the hollow area 122. When the carrier 21 is fixed by the top wall 121, the photosensitive chip 22 is also fixed. In addition, by fixing the carrier 21 to further fix the photosensitive chip 22, the risk of force damage to the photosensitive chip 22 can be reduced compared to directly fixing the photosensitive chip 22. Optionally, the carrier 21 can be locked to the top wall 121 by screws.

[0029] In addition, the imaging module 20 also includes a hydrophobic film (not shown) attached to the surface of the photosensitive chip 22, allowing the imprinted film to be placed on the hydrophobic film surface for imaging. In this case, the risk of the imprinted film directly contacting the photosensitive chip 22 and contaminating or corroding the photosensitive chip 22 can be reduced. Furthermore, the thickness of the hydrophobic film can be less than 0.3 mm. In this case, when the imprinted film is attached to the hydrophobic film, the distance to the photosensitive chip 22 is shorter, which can reduce optical signal loss during transmission and directly obtain an image of nearly the same size as the imprinted film. The hydrophobic film can be a soft film, further reducing costs.

[0030] See also Figure 3 and Figure 4 The housing 10 further includes a seal 15 disposed on the outer edge of the upper surface of the photosensitive chip 22, and the seal 15 is located between the top wall 121 and the photosensitive chip 22 (hydrophobic film). The seal 15 can be made of plastic, plastic or rubber. During assembly, the seal 15 can be first disposed on the photosensitive chip 22 (hydrophobic film), or clamped / adhered to the top wall 121, and then the carrier 21 can be fastened to the top wall 121 by screws. After locking is completed, the seal 15 can seal the gap between the top wall 121 and the photosensitive chip 22, reducing the possibility of liquid or other impurities entering the interior of the base 12 through the gap.

[0031] Also, see Figure 3 and Figure 4 A limiting protrusion 151 can be provided on the surface of the sealing member 15, and a corresponding limiting groove 124 can be opened on the top wall 121. The limiting protrusion 151 can be clamped in the limiting groove 124 to reduce the possibility of the sealing member 15 moving and detaching along the plane where the surface of the photosensitive chip 22 is located, so as to play a waterproof role for a long time.

[0032] In addition, see Figure 5 and Figure 6 ,in Figure 6 The dotted line portion in FIG. 1 shows a matching structure 17 that matches the light shielding member 16. In order to more intuitively express the matching structure 17, Figure 6 There is a certain distance between the matching structure 17 and the shading member 16, but it can be understood that when the upper cover 11 is closed, the shading members 17 and 16 should be in close contact, and the gap therebetween is much smaller than the gap shown in the figure.

[0033] The housing 10 further includes a light shielding member 16 disposed between the upper cover 11 and the base 12 and located on the periphery of the darkroom space 100. The light shielding member 16 is disposed on one of the upper cover 11 and the base 12, and the other of the upper cover 11 and the base 12, which is not provided with the light shielding member 16, has a matching structure 17. The light shielding member 16 being disposed on one of the upper cover 11 and the base 12 may mean that the light shielding member 16 can be assembled on the upper cover 11 or the base 12, or may mean that the light shielding member 16 and the upper cover 11 or the base 12 are integrally formed. The matching structure 17 and the light shielding member 16 can be configured to restrict external light from entering the darkroom space 100 through the gap between the upper cover 11 and the base 12 when the upper cover 11 is closed.

[0034] See also Figure 5 and Figure 6 , the light shielding member 16 has a first step surface 161 and a second step surface 162 that are not coplanar, and the matching structure 17 has a third step surface 171 that mates with the first step surface 161 and a fourth step surface 172 that mates with the second step surface 162. Because the first step surface 161 and the second step surface 162 are not coplanar, when the third step surface 171 contacts the first step surface 161 and the second step surface 162 contacts the fourth step surface 172, it is more difficult for light to enter the darkroom space 100 through the gap between the light shielding member 16 and the matching structure 17. In contrast, if the contact surface between the upper cover 11 and the base 12 is a substantially planar structure, then when the upper cover 11 and the base 12 are in contact, external light will easily enter the darkroom space 100.

[0035] See also Figure 6 The light shielding member has a first groove 163 and at least one second groove 164, both of which are annular. The depth of the first groove 163 is greater than the depth of the second groove 164. The first groove 163 is opened on one of the first step surface 161 and the second step surface 162, and the second groove 164 is opened on the other of the first step surface 161 and the second step surface 162. The matching structure 17 includes a first light-blocking ring 173 and at least one second light-blocking ring 174 arranged around the darkroom space 100. The height of the first light-blocking ring 173 is greater than the height of the second light-blocking ring 174. The first light-blocking ring 173 can be embedded in the first groove 163, and the at least one second light-blocking ring 174 and the at least one second groove 164 respectively correspond to and can be embedded in the corresponding second groove 164.

[0036] The first groove 163, the second groove 164, the first light-blocking ring 173, and the second light-blocking ring 174 are all annular, which can reduce the risk of light from all directions entering the darkroom space 100 through the gap between the upper cover 11 and the base 12. In addition, this multi-ring light-blocking structure (such as the first light-blocking ring 173 and at least one second light-blocking ring 174) can further reduce the risk of light being reflected and entering the darkroom space 100.

[0037] See also Figure 6 In one embodiment, the first step surface 161 is located on the periphery of the second step surface 162, and the first step surface 161 protrudes from the second step surface 162. Correspondingly, the third step surface 171 is located on the periphery of the fourth step surface 172, and the fourth step surface 172 protrudes from the third step surface 171. The first groove 163 is located on the first step surface 161, the second groove 164 is located on the second step surface 162, the first light-blocking ring 173 is located on the third step surface 171, and the fourth light-blocking ring is located on the fourth step surface 172. The number of second grooves 164 and second light-blocking rings 174 can be four, and of course, it can also be two, three, or five.

[0038] The darkroom imaging device 1 further includes a magnetic element provided on the base 12 or the upper cover 11 to apply a force to the upper cover 11 toward the base 12. In this case, the upper cover 11 can be closed by magnetic force when the upper cover 11 is not closed tightly.

[0039] Finally, it should be noted that: the above embodiments are mainly used to illustrate the technical solutions of the present application, and should not be understood as limiting the present application; the above embodiments exemplarily provide a detailed and specific description of the present application, and ordinary technicians in this field can modify the technical solutions described in the above embodiments, or replace some or all of the technical features therein; and these modifications or replacements cannot make the corresponding technical solutions and the technical solutions of the present application constitute different inventions, and therefore should all be included in the scope of the claims and description of the present application. In particular, in the absence of structural conflicts or combination obstacles, the various technical features mentioned in the various embodiments can be combined in any way, and the technical solutions formed by these combinations should not be considered to be outside the scope of the technical solutions of the present application.

Claims

1. A darkroom imaging device, characterized in that: include: The box has a darkroom space. The imaging module is arranged in the box and is used to image the blot membrane in the darkroom space. The box body has an upper cover, a base and a closed cover detection device. The upper cover can be opened and closed relative to the base, and when closed, it blocks external light from entering the darkroom space. The closed cover detection device is arranged on at least one of the base and the upper cover, and is used to detect whether the upper cover is closed.

2. The darkroom imaging device according to claim 1, characterized in that It also includes a processing circuit and an interaction device. The processing circuit is coupled to the cover closing detection device and the interaction device, and is used to output a warning signal when the cover closing detection device detects that the upper cover is not closed.

3. The darkroom imaging device according to claim 2, characterized in that The interactive device includes a light-emitting component arranged on the upper cover or the base, and the light-emitting component can emit light of at least two colors, or the light-emitting component has at least two light-emitting modes.

4. The darkroom imaging device according to claim 1, characterized in that The base has a top wall, the top wall has a hollow area, and the imaging module is located below the hollow area and connected to the top wall.

5. The darkroom imaging device according to claim 4, characterized in that The imaging module includes a carrier and a photosensitive chip. The carrier has a mounting groove. The photosensitive chip is arranged in the mounting groove. The carrier is fixed to the top wall so that the photosensitive chip is located below the hollow area.

6. The darkroom imaging device according to claim 5, characterized in that The imaging module also includes a hydrophobic film adhered to the surface of the photosensitive chip, so that the imprinting film can be placed on the surface of the hydrophobic film for imaging.

7. The darkroom imaging device according to claim 5, characterized in that It also includes a sealing member arranged on the outer edge of the upper surface of the photosensitive chip, and the sealing member is located between the top wall and the photosensitive chip.

8. The darkroom imaging device according to claim 1, wherein The box body also includes a light-shielding member arranged between the upper cover and the base and located on the periphery of the darkroom space. The light-shielding member is arranged on one of the upper cover and the base, and the other of the upper cover and the base where the light-shielding member is not arranged has a matching structure. The matching structure and the light-shielding member are configured to limit external light from entering the darkroom space through the gap between the upper cover and the base when the upper cover is closed.

9. The darkroom imaging device according to claim 8, characterized in that The light shielding member has a first step surface and a second step surface that are not coplanar, and the matching structure has a third step surface for matching with the first step surface and a fourth step surface for matching with the second step surface.

10. The darkroom imaging device according to claim 9, characterized in that The light shielding member has a first groove and at least one second groove, the first groove and the second groove are both annular, and the depth of the first groove is greater than the depth of the second groove, the first groove is opened on one of the first step surface and the second step surface, and the second groove is opened on the other of the first step surface and the second step surface. The matching structure includes a first light-blocking ring and at least one second light-blocking ring arranged in the darkroom space, the height of the first light-blocking ring is greater than the height of the second light-blocking ring, the first light-blocking ring can be embedded in the first groove, and the at least one second light-blocking ring and the at least one second groove respectively correspond to and can be embedded in the corresponding second groove.

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