Experimental mouse plantar swelling measuring device

Abstract

The embodiment of the utility model provides a laboratory mouse plantar swelling measuring device, and relates to the technical field of plantar swelling measurement. The experimental mouse plantar swelling measuring device comprises a fixing table, a placing table is arranged on the surface of the fixing table, the placing table is arranged in a mounting groove formed in the inner surface of the fixing table in a sliding mode, arc-shaped plate bodies are movably installed on the two sides of the end of the placing table, and the arc-shaped plate bodies are arranged in the mounting groove. Elastic tightening assemblies used for flexibly limiting the mouse feet are arranged on the periphery of the end of the fixing table, and each elastic tightening assembly comprises a mounting shaft rod and a rolling pull rope surrounding the surface of the mounting shaft rod. The device can effectively fix laboratory mice of different specifications under the condition that the laboratory mice are not damaged, the activity range of the laboratory mice is reduced, the safety of experimenters is ensured, and the accuracy and repeatability of experiments are improved.

Description

Technical Field

[0001] The utility model relates to the technical field of plantar swelling measurement, in particular to a device for measuring plantar swelling of experimental mice. Background Art

[0002] In pharmacological and biological research, the effects of total alkaloids of Linderae radiata (TALR) on carrageenan-induced hind paw swelling in mice often require a paw swelling assay to assess the drug's anti-inflammatory effect. This process typically involves inducing paw swelling in mice using inflammatory agents such as carrageenan, and then evaluating the drug's anti-inflammatory activity by measuring the degree of swelling. However, when conducting such experiments, the following problems exist:

[0003] Laboratory mice are lively and active, making them difficult to fix quickly and effectively. This not only affects experimental efficiency, but may also lead to inaccurate experimental data due to struggles. Laboratory mice are prone to struggle during the fixation process and may bite the experimenter, posing a safety hazard. Also, due to the differences in the size of laboratory mice, a single fixation device is often unable to adapt to laboratory mice of all specifications, resulting in poor fixation effect.

[0004] Most of the laboratory mouse fixation devices currently on the market can only solve part of the above problems, and there is a lack of a device that can effectively fix laboratory mice of different specifications, ensure the safety of experimenters, and improve the accuracy and repeatability of experiments. Utility Model Content

[0005] The purpose of the utility model is to provide a device for measuring plantar swelling of laboratory mice, which can solve the problem that laboratory mice are active and difficult to fix quickly and effectively, which not only affects the efficiency of the experiment, but also may cause inaccurate experimental data due to struggling. In addition, laboratory mice are prone to struggle during the fixation process and may bite the experimenter, posing a safety hazard. In addition, due to the differences in the size of laboratory mice, a single fixation device is often unable to adapt to laboratory mice of all specifications, resulting in poor fixation effect.

[0006] The utility model provides a device for measuring plantar swelling of experimental rats, comprising: a fixed platform utilization, a placing platform utilization provided on the surface of the fixed platform utilization, and the placing platform utilization is slidably arranged in a mounting groove utilization opened on the inner surface of the fixed platform utilization, wherein arc-shaped plate utilizations are movably installed on both sides of the end of the placing platform utilization, and elastic tightening components are provided around the end of the fixed platform utilization, wherein the elastic tightening components include a mounting shaft utilization and a winding rope utilization surrounding the surface of the mounting shaft utilization, and one end of the winding rope utilization is connected to a fixed soft belt utilization, and measuring components are installed at both front and rear ends of the end of the fixed platform utilization.

[0007] In a specific embodiment, a sliding partition is slidably provided on the inner surface of the fixed table, and the side of the sliding partition is connected to a connecting slide. The four corners of the fixed table surface are penetrated by a first installation groove, and the front and rear ends of the middle part of the fixed table surface are penetrated by a second installation groove.

[0008] In a specific embodiment, a base is provided at the bottom of the fixed platform, and lifting plates are installed on the front and rear sides of the base end, and an oblique support plate is provided in the middle of the base end, wherein a movable slide groove is provided at the end of the base for use with the oblique support plate. At the same time, the surface of the oblique support plate is movably connected with an auxiliary support plate, and a micrometer is clamped at the end of the base.

[0009] In a specific embodiment, an abutting groove is provided on the surface of the placement table, and slide rail grooves are provided on the surface of the placement table and on both sides of the abutting groove. A rotating rod is connected to the middle of the right side of the placement table.

[0010] In a specific embodiment, a guide slot is provided through the middle of the two arc-shaped plates, wherein a support is movably mounted on the surface of the arc-shaped plates, and a pneumatic clamp is movably mounted on the other end of the support.

[0011] In a specific embodiment, the outer surface of the mounting shaft is movably connected to a winding shell one through a bearing, and the upper and lower ends of the winding shell one are respectively connected to a storage cylinder and a winding shell two, and the inner cavity of the winding shell two is installed with a coil spring, and the two ends of the fixed soft belt are knitted with Velcro, and the surface of the fixed soft belt is connected with a rubber pad.

[0012] In a specific embodiment, the bottom of the mounting shaft is movably connected to a fine-tuning shaft 1, the bottom threaded sleeve on the surface of the fine-tuning shaft 1 is provided with an abutment disc 1, and the top of the surface of the fine-tuning shaft 1 is connected to a connecting seat 1.

[0013] In a specific embodiment, the surface of the mounting shaft and the inner cavity of the storage cylinder are provided with a ratchet part, and a pawl part is movably engaged with one side of the ratchet part, and a vertical push rod body is provided through the surface of the pawl part, and a mounting cylinder is provided at the bottom of the vertical push rod body, and an elastic part is installed in the inner cavity of the mounting cylinder.

[0014] In a specific embodiment, the measuring component includes a telescopic part, and the surface of the telescopic part is movably connected to a connecting plate body through a damping shaft, and the other end of the connecting plate body is connected to a flexible plate, wherein the other end of the flexible plate is connected to a mounting sleeve plate, and the inner surface of the mounting sleeve plate is connected to a sleeve rod, and one end of the sleeve rod is installed with the measuring part.

[0015] In a specific embodiment, the bottom of the telescopic part is connected to a fine-tuning shaft rod 2, and the bottom of the fine-tuning shaft rod 2 passes through the mounting groove body 2 and extends to the bottom of the fixed platform, and the upper and lower ends of the surface of the fine-tuning shaft rod 2 are respectively connected to a connecting seat 2 and abutment disc body 2.

[0016] The beneficial effects of the present application are as follows: during swelling measurement, the experimenter places the experimental mouse in the curved plate body and pulls its tail to pull it into the curved plate body until its neck is located in the guide slot, so that the pneumatic clamp can clamp the experimental mouse's neck and initially fix the experimental mouse. The placement table is then turned over, and the pneumatic clamp is used to limit the experimental mouse's abdomen upward. At this time, the experimenter can use the elastic tightening component to limit the experimental mouse's limbs as needed. The curved plate body cooperates with the guide slot and the pneumatic clamp to prevent the experimental mouse from struggling and biting the experimenter when the limbs are limited. At the same time, the restraint of the experimental mouse can be completed by one person.

[0017] When restraining the limbs of the experimental mouse, the reel rope is pulled outward. Under the cooperation of the ratchet and pawl parts, when the reel rope is loosened, it will not be affected by the winding spring. In this way, the limbs of the experimental mouse are limited and fixed by the fixed soft belt and Velcro. The reel rope can be reeled by pressing the pawl part to disengage from the ratchet part. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the following is a brief introduction to the drawings required for use in the embodiments. It should be understood that the following drawings only show certain embodiments of the present invention and therefore should not be regarded as limiting the scope. For ordinary technicians in this field, other relevant drawings can be obtained based on these drawings without creative work.

[0019] Figure 1 This is a schematic diagram of the overall structure of an embodiment of the present utility model;

[0020] Figure 2 This is the second schematic diagram of the overall structure of the embodiment of the utility model;

[0021] Figure 3 This is a schematic diagram of a three-dimensional exploded structure of a fixing platform and a base according to an embodiment of the present invention;

[0022] Figure 4 This is a three-dimensional schematic diagram of the fixing platform structure of an embodiment of the utility model;

[0023] Figure 5 This is a three-dimensional schematic diagram of the placement table structure of an embodiment of the utility model;

[0024] Figure 6This is a schematic diagram of a reversed three-dimensional structure of a placement table according to an embodiment of the present invention;

[0025] Figure 7 This is a three-dimensional schematic diagram of the elastic tightening assembly structure of an embodiment of the utility model;

[0026] Figure 8 This is a schematic three-dimensional diagram of the structure of the measuring component of an embodiment of the utility model;

[0027] Figure 9 This is a schematic three-dimensional diagram of the partial structure of the elastic tightening assembly of an embodiment of the present utility model;

[0028] Figure 10 This is a schematic exploded perspective view of the ratchet and pawl structures of an embodiment of the present invention.

[0029] icon:

[0030] 100, fixed platform; 101, mounting slot; 110, sliding partition; 111, connecting slide; 120, mounting slot body 1; 130, mounting slot body 2;

[0031] 200, base; 210, lifting plate; 220, oblique support plate; 221, movable chute; 230, auxiliary support plate;

[0032] 300, placement table; 301, abutment groove; 302, slide rail groove; 303, rotating rod; 310, arc-shaped plate; 320, guide slot; 330, support member; 340, pneumatic clamp;

[0033] 400, elastic tightening assembly; 410, fine-tuning shaft rod 1; 411, abutting disc 1; 412, connecting seat 1; 420, winding shell 1; 421, winding shell 2; 422, storage cylinder; 430, winding rope; 440, fixing soft belt; 441, rubber cushion; 442, Velcro; 450, coil spring; 460, mounting shaft; 470, ratchet; 471, pawl; 472, vertical push rod; 473, mounting cylinder; 474, elastic member;

[0034] 500, measuring assembly; 510, telescopic member; 520, connecting plate; 521, flexible plate; 522, mounting plate; 530, sleeve rod; 540, measuring member; 550, fine-tuning shaft rod 2; 551, abutment disc 2; 552, connecting seat 2;

[0035] 600. Micrometer. DETAILED DESCRIPTION

[0036] Because lab rats are active and lively, they are difficult to quickly and effectively secure. This not only affects experimental efficiency but can also lead to inaccurate experimental data due to struggles. Furthermore, lab rats are prone to struggle during the securement process, potentially biting the experimenter and posing a safety hazard. Furthermore, due to the varying sizes of lab rats, a single securement device often cannot accommodate all sizes of lab rats, resulting in poor securement. Therefore, the inventors have developed a device for measuring plantar swelling in lab rats. This device, designed to address the aforementioned drawbacks, addresses the issue of lab rats being active and lively, making it difficult to quickly and effectively secure them. This not only affects experimental efficiency but can also lead to inaccurate experimental data due to struggles. Furthermore, due to the varying sizes of lab rats, a single securement device often cannot accommodate all sizes of lab rats, resulting in poor securement.

[0037] The following embodiments of the present invention are described in detail with reference to the accompanying drawings. In the absence of conflict, the following embodiments and features in the embodiments may be combined with each other.

[0038] Please refer to Figures 1 to 10 The present invention provides a device for measuring plantar swelling of experimental mice, comprising a fixed platform 100; a placement platform 300 slidably disposed in a mounting groove 101 provided on the inner surface of the fixed platform 100; a sliding partition 110 is slidably disposed on the inner surface of the fixed platform 100, and a connecting slide 111 is connected to the side of the sliding partition 110; and the position of the elastic tightening component 400 is adjusted to adapt to experimental mice of different sizes, such as Figure 4 As shown, the four corners of the fixed platform 100 are penetrated by a mounting groove 120, which is used in conjunction with a fine-tuning shaft 410, a contact plate 411 and a connecting seat 412 to adjust the position of the measuring component 500. Figure 4 As shown, the front and rear ends of the middle portion of the fixed platform 100 are penetrated by a second mounting groove 130, and the second mounting groove 130 is used in conjunction with the second fine-tuning shaft 550, the second abutment plate 551 and the second connecting seat 552;

[0039] The cam 220 is provided with a plurality of support plates 210, each of which is connected to the bottom of the fixed platform 100. The support plates 210 are provided on the front and rear sides of the fixed platform 100, and the support plates 210 are connected to the bottom of the fixed platform 100. The support plates 210 are provided on the front and rear sides of the fixed platform 100, and the support plates 210 are connected to the bottom of the fixed platform 100. The support plates 220 are provided on the middle part of the end of the base 200. The support plates 220 are provided in two sets.

[0040] In this way, when adjusting the inclination of the fixing platform 100 and the placement platform 300 for measuring mice, the support height of the lifting plate 210 is adjusted, and the inclined support plate 220 and the auxiliary support plate 230 are used to auxiliary support the fixing platform 100 to increase its stability. In this way, the inclination angle of the fixing platform 100 can be effectively changed;

[0041] The end of the base 200 is clamped with a micrometer 600, which can measure the swelling of the plantar of the experimental mouse after the device has restrained the limbs of the experimental mouse.

[0042] The surface of the fixed platform 100 is provided with a placing platform 300, wherein arc-shaped plates 310 are movably installed on both sides of the end of the placing platform 300, and the two arc-shaped plates 310 cooperate with each other to form a semicircular arc, and a gap is left between the two arc-shaped plates 310, wherein the end of the arc-shaped plate 310 close to the placing platform 300 is movably connected to the placing platform 300 through a damping shaft, so that it can be suitable for experimental mice of different specifications; the surface of the placing platform 300 is provided with an abutting groove 301, and the surface of the placing platform 300 and on both sides of the abutting groove 301 are provided with sliding rail grooves 302, wherein the abutting groove 301 and the sliding rail grooves 302 are provided. The rail grooves 302 are interconnected, and the connecting slide 111 on the sliding partition 110 is slidably arranged in the inner cavity of the sliding rail groove 302. A rotating rod 303 is connected to the middle of the right side of the placement table 300, and the other end of the support member 330 extends to the outside of the fixed table 100 and is connected to a handle. Therefore, by rotating the rotating rod 303 with the handle, the placement table 300 can be turned 180 degrees after the sliding partition 110 is pulled out of the placement table 300, so that the bottom surface of the placement table 300 faces upward. In this way, the laboratory mouse on the placement table 300 can be turned over so that its ventral surface faces upward, which facilitates the subsequent positioning of the laboratory mouse's legs.

[0043] A guide slot 320 is formed through the middle of the two arc-shaped plates 310. A support member 330 is movably mounted on the surface of the arc-shaped plates 310. The joint movable end of the support member 330 has a damping property, which can prevent the support member 330 from rotating or swinging at will. The other end of the support member 330 is movably mounted with a pneumatic clamp 340 via a damping universal shaft. The pneumatic clamp 340 can adjust its clamping force as needed.

[0044] As a further optimization of this solution, a pressure sensor is installed on the surface of the pneumatic clamping jaw 340 to detect the clamping force of the pneumatic clamping jaw 340 in real time;

[0045] During the swelling measurement, the experimenter places the experimental mouse on the curved plate 310 and pulls its tail into the curved plate 310 until its neck is located within the guide slot 320. This allows the pneumatic clamp 340 to grip the mouse's neck and initially secure it. The placement table 300 is then flipped over, and the pneumatic clamp 340 restrains the mouse so that its abdomen faces upward. At this point, the experimenter can use the elastic tightening assembly 400 to restrain the mouse's limbs as needed. The curved plate 310, the guide slot 320, and the pneumatic clamp 340 prevent the mouse from struggling and biting the experimenter when its limbs are restrained. Furthermore, restraining the mouse can be performed by only one person.

[0046] Elastic tightening assemblies 400 are provided around the ends of the fixing platform 100 for flexibly limiting the mouse's feet. The elastic tightening assemblies 400 include a mounting shaft 460 and a reel cord 430 wrapped around the mounting shaft 460. One end of the reel cord 430 extends through the outside of the reel housing 1 420 and is connected to a fixing soft belt 440. The fixing soft belt 440 is used to wrap around and secure the experimental mouse's legs to limit their limbs.

[0047] The outer surface of the mounting shaft 460 is movably connected to the winding housing 1 420 via a bearing, and the upper and lower ends of the winding housing 1 420 are respectively connected to the storage cylinder 422 and the winding housing 2 421. The inner cavity of the winding housing 2 421 is installed with a coil spring 450. The winding housing 1 420 is used to reel in the winding rope 430, and the winding housing 2 421 is used to install the coil spring 450. The storage cylinder 422 is used to install the ratchet 470 and the pawl 471.

[0048] Velcro 442 is knitted and connected to both ends of the fixing soft belt 440. The two Velcro 442 are letter-shaped Velcro. The two Velcro 442 cooperate with each other to secure the fixing soft belt 440 when it is wrapped around the experimental mouse. The surface of the fixing soft belt 440 is connected to a rubber pad 441, which can reduce damage to the skin when restraining the experimental mouse's limbs and improve the comfort of limb restraint.

[0049] In order to adjust the position of the elastic tightening assembly 400 to adapt it to laboratory mice of different sizes, the bottom of the mounting shaft 460 is movably connected to a fine-tuning shaft 410. The bottom of the fine-tuning shaft 410 passes through the mounting groove 120 and extends to the bottom of the fixed platform 100. The bottom thread of the surface of the fine-tuning shaft 410 is provided with an abutment disc 411, and the top of the surface of the fine-tuning shaft 410 is connected to a connecting seat 412. The bottom of the connecting seat 412 contacts the top of the fixed platform 100. When the abutment disc 411 is rotated until it contacts the bottom of the fixed platform 100, it cooperates with the connecting seat 412 to adjust the elastic tightening assembly 400 as a whole.

[0050] The surface of the mounting shaft 460 and the inner cavity of the storage cylinder 422 are sleeved with a ratchet member 470, and a pawl member 471 is movably connected to one side of the ratchet member 470, and the surface of the pawl member 471 is penetrated by a vertical push rod body 472, and the bottom of the vertical push rod body 472 is provided with a mounting cylinder 473, wherein the mounting cylinder 473 is located at the bottom of the inner cavity of the storage cylinder 422, and the inner cavity of the mounting cylinder 473 is installed with an elastic member 474, wherein the top of the elastic member 474 is connected to the bottom of the vertical push rod body 472 through a connecting plate, further, the top of the vertical push rod body 472 is penetrated The pawl 471 is driven downwards by the spring 450 to disengage the ratchet 470, and the reel 430 is reeled in. When the reel 430 is pulled out, the ratchet 471 is driven downwards by the spring 450 to disengage the ratchet 470, and the reel 430 is reeled in. When the reel 430 is pulled out, the ratchet 470 and the pawl 471 cooperate to release the reel 430 without being affected by the spring 450. The reel 430 is reeled in by pressing the pawl 471 to disengage the ratchet 470.

[0051] The front and rear ends of the fixed platform 100 are both equipped with measuring components 500, which are used to detect the swelling degree of the plantar fasciitis. The measuring component 500 includes a telescopic member 510, and the surface of the telescopic member 510 is movably connected to a connecting plate 520 via a damping shaft, and the other end of the connecting plate 520 is connected to a flexible plate 521, which is a soft metal and can bend under force, wherein the other end of the flexible plate 521 is connected to a mounting sleeve 522, and the inner surface of the mounting sleeve 522 is connected to a sleeve rod 530, wherein the connection between the sleeve rod 530 and the mounting sleeve 522 is a threaded connection, and the position of the sleeve rod 530 on the mounting sleeve 522 can be adjusted.

[0052] Specifically, the telescopic member 510, the flexible plate 521, and the sleeve rod 530 cooperate to adjust the horizontal, vertical, and front-back positions of the measuring member 540, so that the measuring member 540 can be adapted to different sizes of experimental mice.

[0053] A measuring element 540 is mounted on one end of the sleeve rod 530. The measuring element 540 is a range-finding instrument such as an infrared rangefinder, a laser rangefinder, or an ultrasonic rangefinder. It can be used to immobilize live mice during scientific experiments to facilitate various experimental procedures, such as swelling tests. During the test, the device ensures that the mice remain stable and minimize movement. The measuring element 540 can be placed on the area to be tested to obtain swelling test data.

[0054] In order to flexibly adjust the position of the measuring component 500, the bottom of the telescopic part 510 is connected to the fine-tuning shaft rod 2 550, and the bottom of the fine-tuning shaft rod 2 550 passes through the mounting groove body 2 130 and extends to the bottom of the fixed platform 100, and the upper and lower ends of the surface of the fine-tuning shaft rod 2 550 are respectively connected to the connecting seat 2 552 and the abutment disk body 2 551, wherein the connecting seat 2 552 contacts the surface of the fixed platform 100, and the connection between the abutment disk body 2 551 and the fine-tuning shaft rod 2 550 is a threaded connection. Therefore, when the top of the movable abutment disk body 2 551 is squeezed and contacted with the surface of the fixed platform 100, the measuring component 500 as a whole can be fixed.

[0055] In summary, the working principle of the device for measuring plantar swelling of experimental mice according to the embodiment of the present invention is as follows: when measuring the swelling of the experimental mouse, the experimenter places the experimental mouse in the arc-shaped plate 310, pulls its tail to pull it into the arc-shaped plate 310 until its neck is located in the guide slot 320, so that the pneumatic clamp 340 can clamp the neck of the experimental mouse to preliminarily fix the experimental mouse, and then flips the placement table 300. Under the limiting action of the pneumatic clamp 340, the abdomen of the experimental mouse is facing upward. At this time, the experimenter can use the elastic tightening component 400 to limit the limbs of the experimental mouse as needed, and The cooperation of the guide slots 320 and the pneumatic clamps 340 can prevent the lab mouse from struggling and biting the experimenter when its limbs are restrained. At the same time, the restraint of the lab mouse can be completed by only one person. When restraining the lab mouse's limbs, the reel cord 430 is pulled outward. With the cooperation of the ratchet member 470 and the pawl member 471, when the reel cord 430 is loosened, it will not be affected by the coil spring 450. In this way, the fixed soft belt 440 and the Velcro 442 are used to limit and fix the lab mouse's limbs. The reel cord 430 can be reeled in by pressing the pawl member 471 to disengage from the ratchet member 470.

[0056] The above is only a preferred embodiment of the present invention and is not intended to limit the present invention. For those skilled in the art, various modifications and variations of the present invention are possible. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention shall be included in the scope of protection of the present invention.

Claims

1. A device for measuring swelling of the plantar surface of an experimental mouse, characterized in that: The invention comprises a fixed platform (100), wherein a placing platform (300) is provided on the surface of the fixed platform (100), and the placing platform (300) is slidably provided in a mounting groove (101) provided on the inner surface of the fixed platform (100), wherein arc-shaped plates (310) are movably provided on both sides of the end of the placing platform (300), and elastic tightening components (400) are provided around the end of the fixed platform (100), wherein the elastic tightening components (400) include a mounting shaft (460) and a winding rope (430) wrapped around the surface of the mounting shaft (460), and one end of the winding rope (430) is connected to a fixed soft belt (440), and measuring components (500) are provided at both the front and rear ends of the end of the fixed platform (100).

2. The device for measuring the swelling of the plantar surface of experimental mice according to claim 1, characterized in that: The inner surface of the fixed platform (100) is slidably provided with a sliding partition (110), and the side of the sliding partition (110) is connected to a connecting slide plate (111), and the four corners of the surface of the fixed platform (100) are penetrated by a mounting groove body 1 (120), and the front and rear ends of the middle part of the surface of the fixed platform (100) are penetrated by a mounting groove body 2 (130).

3. The device for measuring rat paw swelling according to claim 2, wherein: A base (200) is provided at the bottom of the fixed platform (100), and lifting plates (210) are installed on both the front and rear sides of the end of the base (200), and an oblique support plate (220) is provided in the middle of the end of the base (200), wherein a movable slide groove (221) used in conjunction with the oblique support plate (220) is opened at the end of the base (200), and at the same time, the surface of the oblique support plate (220) is movably connected to an auxiliary support plate (230), and a micrometer (600) is clamped and provided at the end of the base (200).

4. The device for measuring rat paw swelling according to claim 3, wherein: The surface of the placement platform (300) is provided with an abutting groove body (301), and the surface of the placement platform (300) and the two sides of the abutting groove body (301) are provided with slide rail grooves (302), and the middle part of the right side of the placement platform (300) is connected to a rotating rod (303).

5. The device for measuring rat paw swelling according to claim 4, characterized in that: A guide slot (320) is provided through the middle of the two arc-shaped plates (310), wherein a support member (330) is movably mounted on the surface of the arc-shaped plates (310), wherein a pneumatic clamp (340) is movably mounted on the other end of the support member (330).

6. The device for measuring rat paw swelling according to claim 5, wherein: The outer surface of the mounting shaft (460) is movably connected to the winding shell 1 (420) through a bearing, and the upper and lower ends of the winding shell 1 (420) are respectively connected to the storage cylinder (422) and the winding shell 2 (421), and the inner cavity of the winding shell 2 (421) is installed with a coil spring (450), and the two ends of the fixed soft belt (440) are knitted with Velcro (442), and the surface of the fixed soft belt (440) is connected to a rubber pad (441).

7. The device for measuring rat paw swelling according to claim 6, wherein: The bottom of the mounting shaft (460) is movably connected to a fine-tuning shaft (410), the bottom threaded sleeve of the surface of the fine-tuning shaft (410) is provided with an abutting disc (411), and the top of the surface of the fine-tuning shaft (410) is connected to a connecting seat (412).

8. The device for measuring rat paw swelling according to claim 7, wherein: A ratchet member (470) is provided on the surface of the mounting shaft (460) and in the inner cavity of the storage cylinder (422), and a pawl member (471) is movably engaged on one side of the ratchet member (470), and a vertical push rod body (472) is provided through the surface of the pawl member (471), and a mounting cylinder (473) is provided at the bottom of the vertical push rod body (472), and an elastic member (474) is installed in the inner cavity of the mounting cylinder (473).

9. The device for measuring rat paw swelling according to claim 8, wherein: The measuring assembly (500) comprises a telescopic member (510), wherein the surface of the telescopic member (510) is movably connected to a connecting plate (520) via a damping shaft, and the other end of the connecting plate (520) is connected to a flexible plate (521), wherein the other end of the flexible plate (521) is connected to a mounting sleeve (522), and the inner surface of the mounting sleeve (522) is connected to a sleeve rod (530), and one end of the sleeve rod (530) is mounted with a measuring member (540).

10. The device for measuring the swelling of the plantar surface of experimental mice according to claim 9, characterized in that: The bottom of the telescopic member (510) is connected to a second fine-tuning shaft rod (550), and the bottom of the second fine-tuning shaft rod (550) passes through the second mounting groove body (130) and extends to the bottom of the fixed platform (100), and the upper and lower ends of the surface of the second fine-tuning shaft rod (550) are respectively connected to a second connecting seat (552) and a second abutting disc body (551).

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