Prostate needle biopsy tissue specimen box

Abstract

The utility model relates to the technical field of medical supplies, in particular to a prostate needle biopsy tissue specimen box which comprises a main body and a box cover mutually buckled with the main body, storage grooves are arranged on the main body, embedding boxes are placed in the storage grooves, tissue gaskets are placed in the embedding boxes, and the tissue gaskets are placed in the box cover. The tissue gasket is soaked with stationary liquid, a dyeing area is arranged at one end of the tissue gasket, and tissue dyeing liquid is carried in the dyeing area. The tissue specimen box is integrally designed and can be used for placing and temporarily storing all prostate needle biopsy tissues of a patient; a puncture sample is separated through the storage tank and the embedding box, and a tissue gasket in the embedding box is provided with tissue staining fluid, so that a doctor can conveniently perform staining marking on each puncture tissue so as to identify the head and tail ends of the tissue, and by combining a subsequent pathological report box imaging result, spatial pathological analysis can be performed, and accurate positioning of tumor tissue is facilitated.

Description

Technical Field

[0001] This utility model relates to the field of medical supplies technology, specifically to a prostate biopsy tissue specimen box. Background Technology

[0002] Patients diagnosed with suspected prostate cancer due to elevated prostate-specific antigen (PSA) levels, ultrasound, or MRI findings suggesting suspicious prostate nodules require further pathological examination via prostate biopsy to confirm the diagnosis.

[0003] On the one hand, currently, after a prostate biopsy, the tissue is generally preserved in formalin vials. This method can only preserve one tissue sample per vial, making the procedure cumbersome, requiring a large amount of materials, and it cannot achieve staining and labeling of tumor tissue. On the other hand, current conventional biopsy methods can only obtain the length of each biopsy tissue and the benign / malignant pathological diagnosis, but cannot accurately mark the head and tail of the biopsy tissue. Consequently, it is impossible to reproduce the pathological diagnosis of the biopsy tissue in the patient's prostate MRI, and thus cannot reproduce the spatial location of the tumor tissue in the prostate gland.

[0004] Utility model patent CN204489544U discloses a prostate system puncture biopsy specimen box, which belongs to the category of devices for containing samples. It includes a rectangular main body and a lid that interlocks with it. A handle protrudes from the side of the lid, and a first semi-circular annular ridge and a second semi-circular annular ridge are formed on both sides of the vertical center line of the top surface of the main body. Six cylindrical collection holes are formed in two rows of three within each semi-circular annular ridge, and spare holes of the same shape are formed on the outside of the semi-circular annular ridges. The bottom surface of the lid has a first semi-circular annular groove and a second semi-circular annular groove that interlock with the top surface of the main body, as well as annular ridge-shaped plugs inside and outside the semi-circular annular grooves. This utility model makes specimen collection more convenient, simpler, and standardized for the currently widely used 12-needle system puncture biopsy method for the prostate. Four spare collection holes are provided for targeted puncture at suspicious locations. However, this application cannot stain and label the tissue or reproduce the spatial positioning of tumor tissue. Utility Model Content

[0005] To address the problems existing in the prior art, this utility model provides a prostate biopsy tissue specimen box, which can stain and mark the biopsy tissue to assist in reproducing the spatial location of tumor tissue.

[0006] To achieve the above objectives, the present invention adopts the following technical solution: a prostate biopsy tissue specimen box, comprising a main body and a cover that is interlocked with the main body, wherein a plurality of storage slots are arranged on the main body, an embedding box is placed inside the storage slot, a tissue pad is placed inside the embedding box, the tissue pad is soaked in fixative, and a staining area is provided at one end of the tissue pad, the staining area carrying tissue staining solution.

[0007] Preferably, the embedding box includes a box body and a box lid hinged to the box body, wherein the box body includes a box body frame and a box body bottom, the lower periphery of the box body frame is fixedly connected to the periphery of the box body bottom, a first hollow unit is provided on the box body bottom, the first hollow unit includes a plurality of first hollow individual units arranged in an array, and the box lid includes a cover plate and a second hollow unit provided on the cover plate, the second hollow unit includes a plurality of second hollow individual units arranged in an array.

[0008] Preferably, the box body is closed to the box lid via a plug-in assembly.

[0009] Preferably, the plug-in assembly includes a first slot at the first end of the box frame, a second slot at the second end of the box frame, a first buckle at the first end of the box lid, and a second buckle at the second end of the box lid, wherein the first buckle engages with the first slot and the second buckle engages with the second slot.

[0010] Preferably, the second hollow unit is provided with a dividing strip around its perimeter.

[0011] Preferably, the material of the tissue pad is selected from polytetrafluoroethylene, hydrogel, or polymer.

[0012] This utility model has at least one of the following beneficial effects:

[0013] 1) The prostate biopsy specimen box of this application is an integrated design that can hold and temporarily store all prostate biopsy tissues of a patient;

[0014] 2) Each storage slot of the specimen box in this application contains an embedding cassette, and each embedding cassette contains a tissue pad, which facilitates the doctor to stain and mark each punctured tissue to identify the head and tail of the tissue. Combined with the subsequent pathology report and imaging results, spatial pathological analysis can be performed to assist in the precise localization of tumor tissue. Attached Figure Description

[0015] Figure 1 This is a top view of the specimen box of this utility model;

[0016] Figure 2 This is a schematic diagram of the overall structure of the specimen box of this utility model;

[0017] Figure 3 This is a top view of the embedding box of this utility model;

[0018] Figure 4 This is a schematic diagram of the overall structure of the embedding box of this utility model.

[0019] Figure label:

[0020] 1. Main Body

[0021] 11 Storage slots

[0022] 12 embedding boxes

[0023] 121 Box Body

[0024] 1211 Bottom of the box

[0025] 1211-1 First Hollowed-out Unit

[0026] 1212 Box Frame

[0027] 1212-1 First Card Slot

[0028] 1212-2 Second Card Slot

[0029] 122 box lids

[0030] 1221 Box Lid

[0031] 1221-1 Second Hollowed-out Unit

[0032] 1221-2 First buckle

[0033] 1221-3 Second buckle

[0034] 1221-4 Separator Strip

[0035] 1221-5 Opening section

[0036] 123 Receiving cavity

[0037] 13 Tissue pads

[0038] 131 Staining area

[0039] 2. Cover

[0040] Organization A Detailed Implementation

[0041] The following specific embodiments illustrate the implementation of this utility model. Those skilled in the art can easily understand other advantages and effects of this utility model from the content disclosed in this specification.

[0042] Please see Figures 1 to 4It should be understood that the structures, proportions, sizes, etc., illustrated in the accompanying drawings are merely for illustrative purposes to aid those skilled in the art and are not intended to limit the scope of this invention. Therefore, they have no substantial technical significance. Any modifications to the structure, changes in proportions, or adjustments to size, without affecting the effectiveness and purpose of this invention, should still fall within the scope of the disclosed technical content. Furthermore, the terms "upper," "lower," "left," "right," "middle," and "one" used in this specification are merely for clarity and not intended to limit the scope of this invention. Changes or adjustments to their relative relationships, without substantially altering the technical content, should also be considered within the scope of this invention.

[0043] This utility model embodiment provides a prostate biopsy tissue specimen box, such as Figures 2 to 4 As shown, it includes a main body 1 and a cover 2 that is interlocked with the main body 1. Storage slots 11 are arranged on the main body. An embedding box 12 is placed inside the storage slots 11. A tissue pad 13 is placed inside the embedding box 12. The tissue pad 13 is soaked in fixative. A staining area 131 is provided at one end of the tissue pad 13. The staining area 131 carries tissue staining solution.

[0044] In one specific embodiment, the number of the aforementioned storage slots 11 is 12-18, preferably 18, which can meet the sampling needs of at least one patient.

[0045] Preferably, the length of the storage tank 11 can be 1.0 to 1.2 cm, more preferably 1.1 cm; the width of the storage tank 11 can be 0.9 to 1.1 cm, more preferably 1.0 cm.

[0046] In a preferred embodiment, see details below. Figure 4 The aforementioned embedding box 12 includes a box body 121 and a box cover 122 hinged to the box body 121. The box body 121 includes a box body frame 1212 and a box body bottom 1211. The lower periphery of the box body frame 1211 is fixedly connected to the periphery of the box body bottom 1211. The box body bottom 1211 is provided with a first hollow unit 1211-1, which includes a plurality of first hollow individual units arranged in an array to facilitate dehydration of prostate puncture tissue.

[0047] The cover 122 includes a cover plate 1221 and a second hollow unit 1221-1 disposed on the cover plate 1221. The second hollow unit 1221-1 includes a plurality of second hollow units arranged in an array. Preferably, the first hollow unit 1221-1 and the second hollow unit 1221-1 correspond one-to-one, so that the dehydration and fluid exchange of the prostate puncture tissue in the embedding box 12 are uniform and thorough during the embedding operation.

[0048] In a preferred embodiment, the first hollowed-out unit and the second hollowed-out unit are circular and / or square. It is understood that the first hollowed-out unit and the second hollowed-out unit can also be other shapes, such as rectangles, parallelograms, trapezoids, or triangles, etc., as long as their size is smaller than the puncture sample to avoid the puncture sample being exposed and lost.

[0049] In one specific embodiment, the box body 121 is closed to the box lid 122 via a plug-in assembly.

[0050] Preferred, such as Figure 4 As shown, the above-mentioned plug-in assembly includes a first slot 1212-1 at the first end of the box frame 1212, a second slot 1212-2 at the second end of the box frame 1212, a first buckle 1221-2 at the first end of the box cover 122, and a second buckle 1221-3 at the second end of the box cover 122. The first buckle 1221-2 is engaged with the first slot 1212-1, and the second buckle 1221-3 is engaged with the second slot 1212-2.

[0051] In this utility model, the insertion assembly of the embedding box adopts a connection method of two pairs of slots and buckles, so that the box body 121 and the box cover 122 form a stable structure when they are closed.

[0052] In one specific implementation, such as Figure 4 As shown, the second hollow unit on the cover plate 1221 of the box cover 122 is provided with a partition strip 1221-4 around it. When the box cover 122 is fastened to the cover body 121, the partition strip 1221-4 can form a receiving cavity 123 with the bottom 1211 of the box body for placing the tissue pad 13 and tissue. Preferably, the second end of the box cover 122 is also provided with a snap-opening part 1221-5. By providing a snap-opening part 1221-5 on the box cover 122, the force is better concentrated. Therefore, by forcefully turning the snap-opening part 1221-5, the first buckle 1221-2 and the first slot 1212-1, the second buckle 1221-3 and the second slot 1212-2 are separated by concentrated force, and the box cover 122 is easier to open.

[0053] In a preferred embodiment, such as Figure 2As shown, when the main body of the embedding box 12 is placed in the storage slot 11, the hinge and snap-opening part 1221-5 of the embedding box 12 protrude from the slot of the storage slot 11 of the specimen box body 1, making it easy to take out or put into the storage slot 11.

[0054] In one specific embodiment, such as Figure 3 As shown, the tissue pad 13 is placed within the receiving cavity 123 of the embedding cassette body 121. Preferably, the length and width of the tissue pad 13 are matched with those of the receiving cavity 123.

[0055] More preferably, the tissue pad 13 is a porous, elastic, and absorbent material, such as polytetrafluoroethylene, hydrogel, or a polymer. These materials have good biocompatibility, chemical resistance, and a certain degree of elasticity, and can be used to construct stable tissue samples and prevent the samples from being compressed. Specifically, the aforementioned polymer can be polyurethane, which has elasticity and absorbency; when the sampled tissue is brought close to the tissue pad 13, tissue A can be adsorbed onto the tissue pad 13.

[0056] In a preferred embodiment, the tissue pad 13 is soaked in a tissue fixative. Preferably, the tissue fixative is selected from formalin fixative, Bouin's fixative, acetone fixative, glutaraldehyde fixative, or paraformaldehyde fixative, with formalin being the most preferred. The porous nature of the tissue pad 13 allows for the adsorption of sufficient tissue fixative, thus adequately fixing the punctured tissue A.

[0057] In a preferred embodiment, such as Figure 4 As shown, one end of the tissue pad 12 is provided with a staining solution area 131. The staining solution area carries tissue staining solution and is used to stain one end of the punctured tissue A, so as to facilitate the confirmation of the head and tail positions of tissue A after pathological examination and analysis, and to help determine the spatial position of the tumor tissue in the three-dimensional model of the prostate, so as to facilitate doctors to locate the tumor tissue more accurately.

[0058] In one specific embodiment, the main body 1 of the specimen box is fastened to the cover 2. After sampling is completed, the cover 2 is fastened to the upper part of the main body 1 to protect the specimen box and the contained tissue A.

[0059] This utility model discloses a prostate biopsy tissue specimen cassette. In use, the specimen cassette lid is opened, and the embedding cassette is removed from the storage slot of the main body. The cassette body and lid are then separated by applying force through the snap-opening mechanism. After each prostate biopsy, the doctor unfolds the obtained prostate tissue specimen, determines the orientation of tissue A, and places tissue A on a tissue pad, ensuring the area to be marked is located at the end of the tissue pad containing the tissue staining solution. After placement, the embedding cassette body and lid are fastened together using the plug-in assembly and placed into the storage slot. After all samples have been collected, the specimen cassette lid is closed for subsequent pathological analysis.

[0060] The above embodiments are merely illustrative of the principles and effects of this utility model and are not intended to limit the scope of this utility model. Any person skilled in the art can modify or alter the above embodiments without departing from the spirit and scope of this utility model. Therefore, all equivalent modifications or alterations made by those skilled in the art without departing from the spirit and technical concept disclosed in this utility model should still be covered by the claims of this utility model.

Claims

1. A prostate biopsy tissue specimen cartridge comprising a main body (1) and a cover (2) which is mutually coupled with the main body (1), characterized in that, The main body (1) is provided with a plurality of storage grooves (11), the storage grooves (11) are internally provided with embedding boxes (12), the embedding boxes (12) are internally provided with tissue pads (13), the tissue pads (13) are soaked with fixing liquid, and the tissue pads (13) are provided with a dyeing area (131) at one end.

2. The cartridge of claim 1, wherein The embedding box (12) comprises a box body (121) and a box cover (122) hinged to the box body (121), the box body (121) comprises a box body frame (1212) and a box body bottom (1211), the lower periphery of the box body frame (1212) is fixedly connected with the periphery of the box body bottom (1211), the box body bottom (1211) is provided with a first hollow unit (1211-1), the first hollow unit (1211-1) comprises a plurality of first hollow units arranged in an array, the box cover (122) comprises a cover plate (1221) and a second hollow unit (1221-1) provided on the cover plate (1221), and the second hollow unit (1221-1) comprises a plurality of second hollow units uniformly distributed.

3. The cartridge of claim 2, wherein, The first hollow unit and the second hollow unit are circular and / or square.

4. The cartridge of claim 2, wherein, The box body (121) is closed with the box cover (122) through a plug-in assembly.

5. The cartridge of claim 4, wherein, The plug-in assembly comprises a first clamping groove (1212-1) provided at a first end of the box body frame (1212), a second clamping groove (1212-2) provided at a second end of the box body frame (1212), a first clamping buckle (1221-2) provided at a first end of the box cover (122), and a second clamping buckle (1221-3) provided at a second end of the box cover (122), the first clamping buckle (1221-2) is buckled with the first clamping groove (1212-1), and the second clamping buckle (1221-3) is buckled with the second clamping groove (1212-2).

6. The cartridge of claim 2, wherein The second hollow unit (1221-1) is fixedly provided with a separation strip (1221-4) around, when the box cover (122) is buckled with the box body (121), the separation strip (1221-4) forms an accommodating cavity (123) with the box body bottom (1211).

7. The cartridge of claim 2, wherein The box cover (122) is further provided with an unlocking part (1221-5).

8. The cartridge of claim 6, wherein, The tissue pad (13) is matched with the length and width of the accommodating cavity (123), so that the tissue pad (13) is placed in the embedding box accommodating cavity (123).

9. The cartridge of claim 1, wherein, The material of the tissue pad (13) is selected from polytetrafluoroethylene material, hydrogel material or high polymer.

10. The cartridge of claim 9, wherein, The high polymer is selected from polyurethane.

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