Carboxymethyl chitosan production system

Abstract

The utility model belongs to the technical field of bioengineering, and relates to a carboxymethyl chitosan production system, which comprises a raw material pretreatment unit, an alkalization-carboxymethylation reaction unit, a purification unit, a drying unit and a control unit, the alkalization-carboxymethylation reaction unit comprises a reaction kettle and a multi-path feeding system, a feeding port of the reaction kettle is connected with a discharging port of the raw material pretreatment unit through a material pipeline, the purification unit comprises a centrifugal machine, a dialysis device and an ethanol recovery tower, and the control unit comprises a central processing unit, an actuator and a man-machine interaction screen. The whole production process comprises the steps of raw material pretreatment, alkalization-carboxymethylation reaction, purification and drying, all the units are tightly connected, continuous operation can be achieved, the control unit automatically controls all the devices through the central processing unit, manual intervention and operation time are reduced, and the production rhythm and efficiency are improved.

Description

Technical Field

[0001] This utility model relates to a carboxymethyl chitosan production system, belonging to the field of bioengineering technology. Background Technology

[0002] Carboxymethyl chitosan (CMCS) is an important derivative of chitosan, characterized by good water solubility and excellent biocompatibility, and is widely used in pharmaceuticals, food, and cosmetics. Traditional CMCS production processes typically involve alkalization, carboxymethylation, and purification steps, but existing production systems suffer from the following problems:

[0003] (1) The alkalization and carboxymethylation reactions are carried out in steps, the equipment is dispersed, and the production efficiency is low;

[0004] (2) Inaccurate control of parameters such as temperature and pH during the reaction process affects the degree of substitution and uniformity of the product;

[0005] (3) The low solvent recovery rate in the purification step increases production costs;

[0006] (4) The existing system lacks automated control and relies on manual operation, resulting in poor batch consistency of products.

[0007] Therefore, there is an urgent need to design a highly integrated and automated carboxymethyl chitosan production system. Utility Model Content

[0008] The purpose of this invention is to provide a carboxymethyl chitosan production system that achieves continuous production through integrated design, thereby improving reaction efficiency and product quality.

[0009] The technical solution provided by this utility model is as follows: A carboxymethyl chitosan production system includes a raw material pretreatment unit, an alkalization-carboxymethylation reaction unit, a purification unit, a drying unit, and a control unit. The raw material pretreatment unit includes a washing tank, a dryer, and a pulverizer. The alkalization-carboxymethylation reaction unit includes a reaction vessel and a multi-feed system. The inlet of the reaction vessel is connected to the outlet of the raw material pretreatment unit through a material pipeline. The purification unit includes a centrifuge, a dialysis device, and an ethanol recovery tower. The control unit includes a central processing unit, an actuator, and a human-machine interface screen.

[0010] Based on the above technical solution, the present invention can be further improved as follows:

[0011] Furthermore, the raw material pretreatment unit also includes a vibrating screen, the inlet of which is connected to the outlet of the crusher via a corrugated hose, and a weighing sensor is provided at the bottom of the vibrating screen, which is electrically connected to the central processing unit.

[0012] Furthermore, the reactor is equipped with a stirring device, a temperature sensor, and a cooling device. The stirring device includes a stirrer, a motor, and a speed sensor. The cooling device includes a cooling jacket installed on the outer wall of the reactor and a temperature sensor installed inside the cooling jacket. The temperature sensor, the temperature sensor, and the speed sensor are electrically connected to the central processing unit.

[0013] Furthermore, the multi-feed system includes an alkali feed subsystem, a chloroacetic acid feed subsystem, a rinsing subsystem, a pH sensor, and a level sensor. The alkali feed subsystem includes an alkali storage tank and an alkali metering pump. The chloroacetic acid feed subsystem includes a chloroacetic acid storage tank and a chloroacetic acid metering pump. The rinsing subsystem includes a rinser, a purger, and a waste liquid recovery tank. The pH sensor and the level sensor are electrically connected to the central processing unit.

[0014] Furthermore, the dialysis device includes a hollow fiber dialyzer and an online conductivity monitor, the online conductivity monitor being electrically connected to the central processing unit.

[0015] Furthermore, the actuator is electrically connected to the central processing unit, and the central processing unit controls the operation of the actuator according to preset process parameters.

[0016] The technical solution provided by this utility model has the following advantages compared with the prior art:

[0017] 1. The entire production process of this utility model, from raw material pretreatment, alkalization-carboxymethylation reaction, purification to drying, is closely connected and can achieve continuous operation. The control unit automatically controls each piece of equipment through the central processor, which reduces manual intervention and operation time, and improves production rhythm and efficiency.

[0018] 2. The pulverization operation of the raw material pretreatment unit in this invention increases the specific surface area of ​​the raw materials, making the alkalization-carboxymethylation reaction more complete and rapid. The centrifuge and dialysis device can efficiently complete solid-liquid separation and impurity removal, shortening the purification time and accelerating the overall production progress. The washing tank removes impurities, the dryer controls moisture, the vibrating screen selects raw materials of appropriate particle size, and the weighing sensor precisely controls the input amount, providing a high-quality and stable raw material base for subsequent reactions, which helps to improve the consistency of product quality. The stirring device, temperature sensor, and cooling device in the reaction vessel work together to ensure that the reaction is carried out under suitable temperature and uniform mixing conditions. The multi-feed system precisely controls the amount and time of addition of alkali and chloroacetic acid, ensuring the accuracy of the carboxymethylation reaction and improving the product's substitution degree and quality stability. The ethanol recovery tower recovers and reuses solvents such as ethanol used in the purification process, reducing solvent consumption and procurement costs, and reducing resource waste.

[0019] 3. This utility model receives data from various sensors through the central processing unit of the control unit, monitors the production process in real time, and can promptly issue adjustment instructions to the actuators once the data deviates from the preset parameters, ensuring the stability of the production process and the consistency of product quality. The human-machine interface provides operators with an intuitive operating interface, which can easily set process parameters, view equipment status and production data, realize centralized management and remote monitoring of the entire production system, and improve the efficiency and convenience of production management. Attached Figure Description

[0020] Figure 1 This is a framework diagram of the present utility model;

[0021] Figure 2 This is a data transmission framework diagram of this utility model.

[0022] In the diagram, 1. Raw material pretreatment unit; 11. Washing tank; 12. Dryer; 13. Crusher; 14. Vibrating screen; 15. Weighing sensor; 2. Alkalization-carboxymethylation reaction unit; 21. Reactor; 211. Stirring device; 212. Temperature sensor one; 213. Cooling device; 214. Speed ​​sensor; 215. Temperature sensor two; 22. Multi-feed system; 221. Alkali feed subsystem; 222. Chloroacetic acid feed subsystem; 223. Rinsing subsystem; 224. pH sensor; 225. Liquid level sensor; 226. Alkali metering pump; 227. Chloroacetic acid metering pump; 3. Purification unit; 31. Centrifuge; 32. Dialysis device; 33. Ethanol recovery tower; 34. Online conductivity monitor; 4. Drying unit; 5. Control unit; 51. Central processing unit; 52. Actuator; 53. Human-machine interface screen. Detailed Implementation

[0023] The principles and features of this utility model are described below with reference to examples. The examples are only used to explain this utility model and are not intended to limit the scope of this utility model.

[0024] like Figure 1 and Figure 2As shown, a carboxymethyl chitosan production system includes a raw material pretreatment unit 1, an alkalization-carboxymethylation reaction unit 2, a purification unit 3, a drying unit 4, and a control unit 5. The control unit 5 includes a central processing unit 51, an actuator 52, and a human-machine interface screen 53. The drying unit 4 employs a spray dryer. The raw material pretreatment unit 1 includes a washing tank 11, a dryer 12, a pulverizer 13, and a vibrating screen 14. The inlet of the vibrating screen 14 is connected to the outlet of the pulverizer 13 via a corrugated hose. A weighing sensor 15 is installed at the bottom of the vibrating screen 14 and is electrically connected to the central processing unit 51. The raw material pretreatment unit 1 ensures the purity and particle size uniformity of the raw materials, improving the efficiency of subsequent reactions. The vibrating screen 14 grades the pulverized raw materials, ensuring that the particle size of the reaction raw materials meets the requirements, avoiding pipe blockage or affecting reaction uniformity. The weighing sensor 15 is linked with the central processing unit 51 to achieve accurate metering of raw material input, reducing batch-to-batch errors.

[0025] The alkalization-carboxymethylation reaction unit 2 includes a reactor 21 and a multi-feed system 22. The inlet of the reactor 21 is connected to the outlet of the raw material pretreatment unit 1 via a material pipeline. The reactor 21 is equipped with a stirring device 211, a temperature sensor 212, and a cooling device 213. The stirring device 211 includes a stirrer, a motor, and a speed sensor 214. The cooling device 213 includes a cooling jacket mounted on the outer wall of the reactor 21 and a second temperature sensor 215 mounted inside the cooling jacket. The first temperature sensor 212, the second temperature sensor 215, and the speed sensor 214 are electrically connected to the central processing unit 51. The multi-feed system 22 of the alkalization-carboxymethylation reaction unit 2 enables precise feeding and avoids side reactions. The first temperature sensor 212 and the second temperature sensor 215 monitor the temperature difference in real time and, in conjunction with the cooling jacket, adjust the reaction temperature to avoid localized overheating or incomplete reaction. The speed sensor 214 optimizes the stirring speed to ensure uniform mixing of the reactants. The multi-feed system 22 includes an alkali feed subsystem 221, a chloroacetic acid feed subsystem 222, a rinsing subsystem 223, a pH sensor 224, and a level sensor 225. The alkali feed subsystem 221 includes an alkali storage tank and an alkali metering pump 226. The chloroacetic acid feed subsystem 222 includes a chloroacetic acid storage tank and a chloroacetic acid metering pump 227. The rinsing subsystem 223 includes a flusher, a purger, and a waste liquid recovery tank. The pH sensor 224 and the level sensor 225 are electrically connected to the central processing unit 51. The alkali metering pump 226 and the chloroacetic acid metering pump 227 achieve precise control of the stoichiometric ratio, reducing raw material waste and by-product production. The pH sensor 224 and the level sensor 225 monitor the reaction status in real time, ensuring the reaction process conforms to expectations. The rinsing subsystem 223 reduces cross-contamination between the alkalization and carboxymethylation reactions, lowering waste liquid treatment costs.

[0026] The purification unit 3 includes a centrifuge 31, a dialysis unit 32, and an ethanol recovery tower 33. The dialysis unit 32 includes a hollow fiber dialyzer and an online conductivity monitor 34, which is electrically connected to the central processing unit 51. The actuator 52 is electrically connected to the central processing unit 51, and the central processing unit 51 controls the operation of the actuator 52 according to preset process parameters. The hollow fiber dialyzer improves the removal efficiency of small molecule impurities and shortens the purification time. The online conductivity monitor 34 provides real-time feedback on the purity of the dialysate, avoiding errors from manual sampling and ensuring product consistency.

[0027] In operation, the carboxymethyl chitosan production system of this invention first involves washing raw materials such as shrimp and crab shells in a washing tank 11 to remove impurities and dirt from the surface. After washing, the raw materials are transferred to a dryer 12 for drying to reduce their moisture content and bring them to a suitable processing state. Next, the dried raw materials are pulverized in a pulverizer 13 to reduce particle size, increase the specific surface area for the reaction, and improve the efficiency of subsequent reactions. The pulverized raw materials are then conveyed to a vibrating screen 14 via a corrugated hose. The vibrating screen 14 screens the pulverized raw materials, removing particles that do not meet the particle size requirements. Simultaneously, a weighing sensor 15 at the bottom of the vibrating screen 14 weighs the raw materials in real time and transmits the weight data to a central processing unit 51. The central processing unit 51 determines whether the weight of the raw materials meets the requirements based on preset process parameters. If not, it alerts the operator via a human-machine interface screen 53 for adjustment. The pre-treated raw materials are then conveyed to a reaction vessel 21 via a material pipeline. Before the reaction begins, a multi-feed system 22 starts operating. During the alkalization reaction stage, the alkali metering pump 226 in the alkali feed subsystem 221 draws a certain amount of alkali from the alkali storage tank and delivers it to the reactor 21 according to a preset flow rate and time, providing an alkaline environment for the alkalization reaction. During the carboxymethylation reaction stage, the chloroacetic acid metering pump 227 in the chloroacetic acid feed subsystem 222 draws chloroacetic acid from the chloroacetic acid storage tank and adds it to the reactor 21 at an appropriate flow rate and time to undergo a carboxymethylation reaction with the alkalized raw materials. Simultaneously, the pH sensor 224 and level sensor 225 inside the reactor 21 monitor the pH value and liquid level of the material in the reactor 21 in real time and transmit the data to the central processing unit 51. The central processing unit 51, according to preset process parameters, controls the flow rates of the alkali metering pump 226 and the chloroacetic acid metering pump 227 through the actuator 52, thereby adjusting the pH value and liquid level inside the reactor 21. During the reaction, the stirring device 211 inside the reactor 21 operates continuously. The motor drives the stirrer to rotate, thoroughly stirring the reactants to ensure a more uniform reaction. The speed sensor 214 monitors the stirrer's speed in real time and feeds the data back to the central processing unit 51, which can adjust the motor speed as needed. The temperature sensor 212 inside the reactor 21 monitors the temperature of the reactants in real time, and the temperature sensor 215 in the cooling device 213 monitors the temperature of the coolant in the cooling jacket. When the reaction temperature is too high, the central processing unit 51 controls the cooling device 213 to operate, using the coolant in the cooling jacket to remove the heat generated by the reaction and control the reaction temperature within a preset range. After the reaction is completed, the rinsing subsystem 223 starts working. The rinsing device rinses the reactor 21, and the purging device purges the reactor 21 to remove residual materials and impurities. The waste liquid generated from rinsing and purging is collected in a waste liquid recovery tank.After the reaction is complete, the material is conveyed to centrifuge 31 for solid-liquid separation. Centrifuge 31 uses centrifugal force generated by high-speed rotation to separate the carboxymethyl chitosan solid from the reaction liquid. The separated carboxymethyl chitosan solid enters dialysis unit 32 for further purification. The hollow fiber dialyzer in dialysis unit 32 uses the principle of a semi-permeable membrane to remove small molecule impurities from the carboxymethyl chitosan. The conductivity online monitoring instrument 34 monitors the conductivity of the dialysate in real time. When the conductivity reaches the preset value, it indicates that the dialysis has achieved the expected effect, and the central processing unit 51 can control the end of the dialysis process. During the purification process, solvents such as ethanol are recovered through ethanol recovery tower 33 to achieve solvent recycling and reduce production costs. The purified carboxymethyl chitosan enters drying unit 4 for drying treatment. Drying unit 4 removes moisture from the carboxymethyl chitosan to meet the product's moisture content requirements, finally obtaining the finished carboxymethyl chitosan product.

[0028] The central processing unit 51 of the control unit 5 is the core of the entire production system. It receives data from various sensors (such as the weighing sensor 15, temperature sensor, pH sensor 224, level sensor 225, speed sensor 214, and online conductivity monitor 34) and compares it with preset process parameters. Based on the comparison results, the central processing unit 51 sends control commands to the actuator 52, thereby achieving automated control of the entire production process. Operators can set production process parameters, view real-time data and equipment status during production, and monitor and adjust the production process through the human-machine interface 53. Simultaneously, the central processing unit 51 can also store and analyze production data, providing a basis for production process optimization and quality control.

[0029] The above description is only a preferred embodiment of the present utility model and is not intended to limit the present utility model. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.

Claims

1. A carboxymethyl chitosan production system characterized by comprising: The application relates to a production device for carboxymethyl cellulose, which comprises a raw material pretreatment unit (1), an alkalization-carboxymethylation reaction unit (2), a purification unit (3), a drying unit (4) and a control unit (5), wherein the raw material pretreatment unit (1) comprises a cleaning tank (11), a dryer (12) and a pulverizer (13), the alkalization-carboxymethylation reaction unit (2) comprises a reaction kettle (21) and a multi-path feeding system (22), the feeding port of the reaction kettle (21) is connected with the discharge port of the raw material pretreatment unit (1) through a material pipeline, the purification unit (3) comprises a centrifuge (31), a dialysis device (32) and an ethanol recovery tower (33), and the control unit (5) comprises a central processing unit (51), an executor (52) and a man-machine interaction screen (53).

2. The carboxymethyl chitosan production system according to claim 1, wherein, The raw material pretreatment unit (1) further comprises a vibrating screen (14), the feeding port of the vibrating screen (14) is connected with the discharge port of the pulverizer (13) through a corrugated hose, a weighing sensor (15) is arranged at the bottom of the vibrating screen (14), and the weighing sensor (15) is electrically connected with the central processing unit (51).

3. The carboxymethyl chitosan production system according to claim 1, wherein, The reaction kettle (21) is provided with a stirring device (211), a temperature sensor one (212) and a cooling device (213), the stirring device (211) comprises a stirrer, a motor and a rotating speed sensor (214), the cooling device (213) comprises a cooling jacket arranged on the outer wall of the reaction kettle (21) and a temperature sensor two (215) arranged in the cooling jacket, and the temperature sensor one (212), the temperature sensor two (215) and the rotating speed sensor (214) are electrically connected with the central processing unit (51).

4. The carboxymethyl chitosan production system according to claim 1, wherein, The multi-path feeding system (22) comprises an alkali liquor feeding subsystem (221), a chloroacetic acid feeding subsystem (222), a flushing subsystem (223), a pH sensor (224) and a liquid level sensor (225), the alkali liquor feeding subsystem (221) comprises an alkali liquor storage tank and an alkali liquor metering pump (226), the chloroacetic acid feeding subsystem (222) comprises a chloroacetic acid storage tank and a chloroacetic acid metering pump (227), the flushing subsystem (223) comprises a flusher, a purger and a waste liquid recovery tank, and the pH sensor (224) and the liquid level sensor (225) are electrically connected with the central processing unit (51).

5. The carboxymethyl chitosan production system according to claim 1, wherein, The dialysis device (32) comprises a hollow fiber dialyzer and an online conductivity monitor (34), and the online conductivity monitor (34) is electrically connected with the central processing unit (51).

6. The carboxymethyl chitosan production system according to claim 1, wherein The executor (52) is electrically connected with the central processing unit (51), and the central processing unit (51) controls the action of the executor (52) according to preset process parameters.

Images