Biological tissue embedding machine

By designing an automated biological tissue embedding machine, the problems of low efficiency and inconsistent quality caused by manual operation have been solved, realizing an efficient and reliable embedding process that meets the needs of rapid scientific research and medical treatment.

CN224004786UActive Publication Date: 2026-03-17GANSU ACAD OF MEDICAL SCI
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Patent Information

Application Number
CN202520637915.7
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2025-04-07
Publication Date
2026-03-17
Estimated Expiration
2035-04-07

AI Technical Summary

Technical Problem

In current technologies, biological tissue embedding mainly relies on manual operation, which results in a heavy workload, low efficiency, and inconsistent quality, making it difficult to meet the needs of efficient sample processing in the rapidly developing scientific research and medical fields.

Method used

Design a biological tissue embedding machine, including a worktable, a wax melting machine, a nozzle, an electric slide rail, a pushing component, and a cooling plate, to automate the paraffin filling and cooling processes, ensuring that each biological tissue is processed under the same conditions.

Benefits of technology

It significantly reduces manual operation time, improves work efficiency, ensures the consistency and reliability of embedding results, and meets the needs of efficient processing of large batches of biological tissues.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the technical field of laboratory instruments, in particular to a biological tissue embedding machine which comprises a working table, a wax melting machine, a spray head, a placing plate, a collecting frame, a first electric sliding rail and a first sliding block, and the wax melting machine and the like are connected to the working table; the wax melting machine is connected with a spray head, the top of the workbench is connected with a first electric sliding rail and a second electric sliding rail, and the first electric sliding rail is connected with a first sliding block. The first electric sliding rail, the second electric sliding rail and the pushing assembly are arranged, so that certain repetitive and time-consuming steps such as paraffin filling and cooling can be automatically completed, the time required by manual operation is remarkably shortened, the whole embedding process is accelerated, the working efficiency of a laboratory is improved, and when the number of biological tissues is large, the working efficiency of the laboratory is improved. Each biological tissue can be processed under the same condition, and the difference caused by human factors is reduced, so that the consistency and reliability of embedding results are improved.
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Description

Technical Field

[0001] This utility model relates to the field of laboratory equipment technology, and in particular to a biological tissue embedding machine. Background Technology

[0002] Tissue embedding is a technique used in pathological and biological research, primarily for preparing tissue samples for microscopic observation. This process aims to maintain the tissue's natural structure while ensuring it is robust enough for sectioning. First, a tissue sample of interest is selected and immobilized to prevent natural degradation and preserve its in vivo morphology as much as possible. Then, the tissue is immersed in an embedding medium such as molten paraffin or resin. Once the medium cools and solidifies, it forms a solid block, the embedding block. This embedding method facilitates the cutting into thin sections using a microtome (such as a microtome), providing ideal sample preparation for subsequent staining, immunohistochemical analysis, or electron microscopy. Through this method, scientists can observe cellular structures and pathological changes in detail, which is of great significance for disease research and diagnosis.

[0003] Currently, biological tissue embedding is mainly performed manually throughout the entire process. When processing large quantities of biological tissue, manually embedding too many samples at once not only increases the workload but also easily leads to inconsistent embedding quality. Manual operation makes it difficult to precisely control the time and conditions of each step, which may result in some tissue samples failing to achieve the desired processing effect, affecting the final section quality and observation results. The manual embedding of a large number of samples also greatly limits work efficiency, making the entire research or diagnostic process time-consuming and unable to meet the needs of the rapidly developing scientific research and medical fields for efficient sample processing. Utility Model Content

[0004] In order to overcome the shortcomings of the prior art, the purpose of this utility model is to provide a biological tissue embedding machine.

[0005] A biological tissue embedding machine includes a worktable, a wax melting machine, a nozzle, a placement plate, a collection frame, a first electric slide rail, a second electric slide rail, a first slider, a second slider, a cooling plate, and a pushing assembly. The wax melting machine, the placement plate, and the collection frame are connected to the worktable. The nozzle is connected to the wax melting machine. The first electric slide rail and the second electric slide rail are connected to the top of the worktable. The first slider is connected to the first electric slide rail, and the second slider is connected to the second electric slide rail. The cooling plate and the pushing assembly are connected to the top of the worktable.

[0006] Preferably, the slide also includes a magnetic block, with both the first and second sliders connected to a magnetic block.

[0007] Preferably, the pushing assembly includes a first electric push rod, a first push block, a second electric push rod, and a second push block. The first electric push rod and the second electric push rod are connected to the top of the worktable. The first push block is connected to the telescopic rod of the first electric push rod, and the second push block is connected to the telescopic rod of the second electric push rod. The first push block is located between the wax melting machine and the placement plate, and the second push block is located on the side of the cooling plate away from the first electric slide rail.

[0008] Preferably, the system also includes guide blocks, with two guide blocks connected to the top of the worktable, both of which are located between the placement plate and the cooling plate.

[0009] Preferably, a limit block is also included, and the limit block is connected to the placement plate.

[0010] Preferably, the system also includes a connecting seat, a cylinder, and a pressure plate. The connecting seat is connected to the side of the worktable near the cooling plate, the cylinder is connected to the connecting seat, and the pressure plate is connected to the piston rod of the cylinder.

[0011] The beneficial effects of this utility model are as follows: This utility model is equipped with a first electric slide rail, a second electric slide rail and a pushing component, which can automatically complete some repetitive and time-consuming steps, such as paraffin filling and cooling, thereby significantly reducing the time required for manual operation, helping to speed up the entire embedding process, improving the working efficiency of the laboratory, and ensuring that each biological tissue is processed under the same conditions when there are a large number of biological tissues, reducing the differences caused by human factors, thereby improving the consistency and reliability of the embedding results. Attached Figure Description

[0012] Figure 1 This is a three-dimensional structural diagram of the present invention.

[0013] Figure 2 This is a schematic diagram of the structure of the first electric slide rail, the second electric slide rail, and the collection frame of this utility model.

[0014] Figure 3 This is a schematic diagram of the connecting seat, cylinder, and pressure plate structure of this utility model.

[0015] Figure 4 This is a schematic diagram of the structure of the cooling plate, placement plate, and magnetic block of this utility model.

[0016] Explanation of reference numerals in the attached drawings: 1-Workbench, 101-Placement plate, 2-Wax melting machine, 3-Nozzle, 4-Collection frame, 5-First electric slide rail, 6-Second electric slide rail, 7-First slider, 8-Second slider, 9-Magnetic block, 10-Refrigeration plate, 11-First electric push rod, 12-First push block, 13-Second electric push rod, 14-Second push block, 15-Guide block, 16-Limit block, 17-Connecting seat, 18-Cylinder, 19-Pressure plate. Detailed Implementation

[0017] The present invention will be further described below with reference to the accompanying drawings and specific embodiments.

[0018] A biological tissue embedding machine, such as Figures 1-4 As shown, the system includes a worktable 1, a wax melting machine 2, a nozzle 3, a placement plate 101, a collection frame 4, a first electric slide rail 5, a second electric slide rail 6, a first slider 7, a second slider 8, a magnet 9, a cooling plate 10, a pushing assembly, a guide block 15, a limiting block 16, a connecting seat 17, a cylinder 18, and a pressure plate 19. The wax melting machine 2, the placement plate 101, and the collection frame 4 are fixedly connected to the rear top of the worktable 1. The nozzle 3 is fixedly connected to the wax melting machine 2, and the placement plate 101 is located directly below the nozzle 3. The first electric slide rail 5 and the second electric slide rail 6 are fixedly connected to the right top of the worktable 1. The first slider 7 is fixedly connected to the first electric slide rail 5, and the second slider 8 is fixedly connected to the second electric slide rail 6. Magnets 9 are fixedly connected to the top of both the first slider 7 and the second slider 8. Magnets 9 can attract the paraffin embedding box. The first slider 7 and the second slider 8 are fixed to prevent the paraffin embedding box from falling due to movement. A cooling plate 10 is fixedly connected to the front top of the worktable 1. A pushing component is connected to the left top of the worktable 1. Two guide blocks 15 are fixedly connected to the top of the worktable 1. The guide blocks 15 are located between the placement plate 101 and the cooling plate 10. During the process of the paraffin embedding box being pushed from the placement plate 101 to the cooling plate, the guide blocks 15 can prevent the paraffin embedding box from shifting, ensuring that the pressure plate 19 can press the biological tissue normally. A limit block 16 is fixedly connected to the top of the placement plate 101. A connecting seat 17 is fixedly connected to the front top of the worktable 1. A cylinder 18 is fixedly connected to the connecting seat 17. A pressure plate 19 is fixedly connected to the piston rod of the cylinder 18. The pressure plate 19 is located directly above the cooling plate 10.

[0019] like Figure 1 and Figure 2 As shown, the pushing assembly includes a first electric push rod 11, a first push block 12, a second electric push rod 13, and a second push block 14. The first electric push rod 11 and the second electric push rod 13 are fixedly connected to the top of the worktable 1. The first push block 12 is fixedly connected to the telescopic rod of the first electric push rod 11, and the second push block 14 is fixedly connected to the telescopic rod of the second electric push rod 13. The first push block 12 is located between the wax melting machine 2 and the placement plate 101, and the second push block 14 is located on the side of the cooling plate 10 away from the first electric slide rail 5.

[0020] Initially, paraffin wax is placed into the wax melting machine 2 to melt it into a liquid. During tissue embedding, the tissue is first removed from the embedding cassette using tweezers, then placed back into the paraffin embedding cassette using the same tweezers. The cassette is then placed on the second slider 8, and the second slider 8 is moved closer to the placement plate 101 via the second electric slide rail 6. The paraffin embedding cassette is then manually pushed onto the placement plate 101, bringing it into contact with the limiting block 16. The limiting block 16 ensures that the paraffin embedding cassette is positioned correctly on the placement plate 101. To ensure that the nozzle 3 can evenly fill the paraffin embedding box with paraffin wax, avoiding gaps or insufficient paraffin wax, and ensuring the integrity and quality of subsequent sections, the first electric push rod 11 drives the first push block 12 to move forward, causing the first push block 12 to push the paraffin embedding box to the top of the cooling plate 10. The cylinder 18 drives the pressure plate 19 to move downward, causing the pressure plate 19 to squeeze the biological tissue in the paraffin embedding box, expelling air bubbles between the biological tissue and paraffin wax, allowing the paraffin wax to better penetrate into the interstitial spaces of the biological tissue, and enhancing the bonding between the biological tissue and paraffin wax. The combined effect allows for easier cutting of continuous, uniform thin slices in subsequent sections. The cooling plate 10 cools the paraffin at the bottom of the embedding cassette, enabling it to reach the required hardness more quickly and thus more stably fix the position and morphology of the biological tissue sample. The first electric slide rail 5 drives the first slider 7 to move closer to the cooling plate 10, while the second electric push rod 13 drives the second push block 14 to move to the right, pushing the paraffin embedding cassette to the top of the first slider 7. The first electric slide rail 5 then drives the first slider 7 away from the cooling plate 10, removing the paraffin embedding cassette and placing it in the placement plate 101. After the paraffin cools, sections can be cut. This embedding machine can automatically complete repetitive and time-consuming steps, such as paraffin filling and cooling, significantly reducing the time required for manual operation. This helps to speed up the entire embedding process, improve laboratory efficiency, and ensure that each biological tissue is processed under the same conditions when there are many tissues, reducing differences caused by human factors and improving the consistency and reliability of the embedding results.

[0021] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of this utility model and are not intended to limit the scope of protection of this utility model. Although this utility model has been described in detail with reference to preferred embodiments, those skilled in the art should understand that modifications or equivalent substitutions can be made to the technical solutions of this utility model without departing from the essence and scope of the technical solutions of this utility model.

Claims

1. A biological tissue embedding machine comprising a workbench (1), a wax melting machine (2), a spray head (3), a placing plate (101) and a collection frame (4), the workbench (1) being connected with the wax melting machine (2), the placing plate (101) and the collection frame (4), the wax melting machine (2) being connected with the spray head (3), characterized in that, It also includes the first electric sliding rail (5), the second electric sliding rail (6), the first sliding block (7), the second sliding block (8), the refrigeration plate (10) and the pushing assembly, the top of the workbench (1) is connected with the first electric sliding rail (5) and the second electric sliding rail (6), the first electric sliding rail (5) is connected with the first sliding block (7), the second electric sliding rail (6) is connected with the second sliding block (8), the top of the workbench (1) is connected with the refrigeration plate (10) and the pushing assembly.

2. The biological tissue embedding machine according to claim 1, wherein It also includes the magnetic block (9), the first sliding block (7) and the second sliding block (8) are connected with the magnetic block (9).

3. The biological tissue embedding machine according to claim 2, wherein The pushing assembly includes the first electric push rod (11), the first push block (12), the second electric push rod (13) and the second push block (14), the top of the workbench (1) is connected with the first electric push rod (11) and the second electric push rod (13), the telescopic rod of the first electric push rod (11) is connected with the first push block (12), the telescopic rod of the second electric push rod (13) is connected with the second push block (14), the first push block (12) is located between the wax melting machine (2) and the placing plate (101), and the second push block (14) is located on the side of the refrigeration plate (10) away from the first electric sliding rail (5).

4. The biological tissue embedding machine according to claim 3, wherein The embedding machine also includes the guide block (15), and the top of the workbench (1) is connected with two guide blocks (15), and the guide blocks (15) are located between the placing plate (101) and the refrigeration plate (10).

5. The biological tissue embedding apparatus according to claim 4, wherein The embedding machine also includes the limiting block (16), and the placing plate (101) is connected with the limiting block (16).

6. A biological tissue embedding apparatus according to claim 5, wherein The embedding machine also includes the connecting seat (17), the air cylinder (18) and the pressing plate (19), and the side of the workbench (1) close to the refrigeration plate (10) is connected with the connecting seat (17), the connecting seat (17) is connected with the air cylinder (18), and the piston rod of the air cylinder (18) is connected with the pressing plate (19).