Thrombectomy devices with lateral and vertical bias
Thrombectomy systems with curved tubular cutting devices address the challenge of effectively removing thrombus tissue in blood vessels by minimizing vascular injury and embolus release.
Patent Information
- Authority / Receiving Office
- HK · HK
- Patent Type
- Applications
- Current Assignee / Owner
- AVANTEC VASCULAR CORP
- Filing Date
- 2026-04-16
- Publication Date
- 2026-07-10
AI Technical Summary
Existing thrombectomy devices struggle to effectively cut and remove various types of thrombus tissue in blood vessels while minimizing the risk of vascular injury and embolus release.
Thrombectomy systems with lateral and longitudinal bias provide curved tubular cutting devices designed to efficiently cut and collect thrombus tissue, reducing the risk of vascular injury and embolus release.
The systems effectively cut and remove thrombus tissue, reducing vascular injury and the risk of worsening stenosis by safely collecting debris.
Smart Images
Figure 00000000_0000_ABST
Abstract
Description
Thrombectomy devices with lateral and longitudinal bias provide thrombectomy systems with curved tubular cutting devices and methods of use. These systems, devices, and methods are capable of: (i) effectively cutting and removing various types of thrombus tissue in blood vessels, including soft, ligamentous, and hard tissue; (ii) safely collecting and removing tissue debris to avoid embolus release; and (iii) effectively treating blood vessels while reducing the risk of vascular injury that could worsen vascular stenosis. Abstract
Claims
WE CLAIM:
1. A thrombectomy device, comprising a flexible rotating shaft with a proximal end, a distal end, and a lumen; a curved, tubular cutter operably connected to the distal end of the flexible rotating shaft, the tubular cutter including a head with an axis with a mouth having a z-axis, a neck connected to the head and having an axis of rotation, and an angle, θz, ranging from 90oto 135o, between the z-axis of the mouth and the axis of rotation, the mouth the configured with a leading edge having a highest height, h-leading; a trailing edge having a lowest height, h-trailing; a vertical bias ratio of h-leading / h-trailing ranging from 1.05 to 2.0; a distance, BL, between the axis of rotation and the leading edge; a distance, BT, between the axis of rotation and the trailing edge; and, a lateral bias ratio of BL / BT ranging from 1.05 to 2.0; and, a vacuum port configured for operable communication with a vacuum source to facilitate transport of the tissue out of the subject.
2. The device of claim 1, wherein the cutter is deflected from the axis of rotation to create a deflection distance between the leading edge of the cutter and the axis of rotation.
3. The device of claim 1, wherein the axis of the head is at a vertical angle, Φ, with the axis of rotation, wherein Φ ranges from 0oto 90oto create a deflection distance between the leading edge ofand the axis of rotation.
4. The device of claim 1, wherein the axis of the head is at a lateral angle, θo, with the axis of rotation, wherein θo ranges from 0oto 90oto create a deflection distance between the leading edge of the cutter and the axis of rotation.
5. The device of claim 1, wherein the flexible rotating shaft is deflected at an angle, θm, with the axis of rotation to form a curve region in the flexible rotating shaft, wherein θm ranges from 0-90 degrees to create a deflection distance between the leading edge of the cutter and the axis of rotation.
6. The device of claim 1, wherein the mouth has a cross-sectional area that is equal to, or less than, the lumen of the flexible, rotating shaft.
7. The device of claim 5, wherein the z-axis of the mouth is an angle, θr, from a plane containing the curve region to open the mouth toward the target site for the tissue for removal.
8. The device of claim 5, further comprising a straightening sheath.
9. A system comprising the device of claim 1, the system further comprising a handle that includes a motor operably connected to a drive assembly that includes the flexible rotating shaft and the cutter, the motor configured to provide a rotational movement to the flexible, rotating shaft for rotating the cutter.
10. A system comprising the device of claim 5, the system further comprising a handle that includes a motor operably connected to a drive assembly that includes the flexible rotating shaft and the cutter, the motor configured to provide a rotational movement to the flexible, rotating shaft for rotating the cutter.
11. The system of claim 10, wherein the z-axis of the mouth is an angle, θr, from a plane containing the curve region to open the mouth toward the target site for the tissue for removal.
12. The system of claim 5, further comprising a straightening sheath.
13. A system comprising the device of claim 1, further comprising a vacuum source, and wherein the vacuum port is in operable connection with the vacuum for removal of the tissue from the system.
14. A system comprising the device of claim 5, further comprising a vacuum source; wherein the vacuum port is in operable connection with the vacuum for removal of the tissue from the system.
15. A method of performing a thrombectomy using the device of claim 1, the method comprising: creating a point of entry in a vascular lumen of the subject; inserting the thrombectomy device into the vascular lumen; delivering the cutter to the target site having the tissue for removal; cutting the tissue from the vascular lumen with the cutter;and, removing the thrombectomy device from the vascular lumen of the subject.
16. The method of claim 15, the method further comprising inserting a guidewire in the point of entry and delivering the guidewire to the target location of the thrombus, and guiding the thrombectomy device to the location of the thrombus on the guidewire.
17. The method of claim 15, the method further comprising discharging the tissue from the vascular lumen with a vacuum.
18. A method of performing a thrombectomy in a subject using the device of claim 5, and the method comprises: creating a point of entry in a vascular lumen of the subject; inserting the thrombectomy device into the vascular lumen; delivering the cutter to the target site having the tissue for removal; cutting tissue from the vascular lumen with the cutter; and, removing the thrombectomy device from the vascular lumen of the subject.
19. The method of claim 18, the method further comprising inserting a guidewire in the point of entry and delivering the guidewire to the target location of the tissue, and guiding the cutter to the location of the thrombus on the guidewire.
20. The method of claim 18, the method further comprising discharging the tissue from the vascular lumen with a vacuum.