Adhesion-preventing agent and method, for preventing adhesion using the same

Abstract

The present invention relates to an adhesionpreventing agent comprising hyaluronic acid. carboxymethyl cellulose, and alginate, and a method for preventing adhesion, comprising contacting the surface of local organs of an individual with said adhesion-preventing agent. wherein the hyaluronic acid has a molecular weight of 500,000 to 10,000,000 Daltons (Da), and wherein the adhesion-preventing agent has a viscosity of 400 to 1000 centiposes (cP). The adhesion-preventing agent of the present invention comprises 0.1 to 10% by weight of the hyaluronic acid, 0.1 to 8% by weight of the carboxymethyl cellulose, and 0.01 to 5% by weight of the alginate, based on the total weight of the adhesion-preventing agent. The adhesionpreventing agent comprising hyaluronic acid, carboxymethyl cellulose and alginate according to the present invention shows excellent biocompatibility, in vivo durability, and tissue adhesiveness, and ultimately exhibits excellent adhesion preventing effects.