Methods of sequestering target elements
Lanmodulin protein (LanM) addresses the lack of efficient REE and RM binding macromolecules by selectively binding and desorbing these elements, facilitating their extraction and purification for industrial and pharmaceutical applications.
Patent Information
- Authority / Receiving Office
- AU · AU
- Patent Type
- Applications
- Current Assignee / Owner
- LAWRENCE LIVERMORE NAT SECURITY LLC
- Filing Date
- 2021-02-12
- Publication Date
- 2026-07-16
AI Technical Summary
There is a lack of naturally efficient rare-earth element (REE) and radiometal (RM)-binding macromolecules, leading to the industry's neglect of proteins for REE and RM life cycle management, and a need for bio-sourced or bio-inspired chelators for sustainable extraction and sequestration.
The use of lanmodulin protein (LanM) to sequester target elements such as REEs, Bi, Tl, and In by binding them in an aqueous solution at pH 2.5 to 6.5, followed by pH adjustment to desorb the elements, allowing for repeated cycles of recovery and separation.
LanM effectively binds and desorbs REEs and RMs with high selectivity and fidelity, enabling efficient extraction and purification from industrial feedstocks and potential use in pharmaceutical compositions for cancer treatment and tumor imaging.
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