AIDS diagnosis device with easy-to-remove liquid flow driving component

Abstract

The invention relates to an AIDS diagnosis device with an easy-to-remove liquid flow driving component, and belongs to the field of analytical testing. A technical obstacle exists in the manufacture of a substrate of an AIDS-diagnosis microfluidic chip using cheap and easy-to-process polydimethylsiloxane (PDMS), the surface of the PDMS is strongly-hydrophobic, the effect of targeted surface modification or surface finish is difficult to last, and the AIDS diagnosis device with the easy-to-remove liquid flow driving component aims to solve the series of relevant problems. Main points of the AIDS diagnosis device with the easy-to-remove liquid flow driving component are as follows: the PDMS with an original ecological surface is selected as the substrate, an elastic force clip is elastically snapped and positioned in a position near a sample liquid flow terminal of the microfluidic chip, wherein miniature ultrasonic transducers are attached to clamping arms of the elastic force clip, meanwhile an ultrasonic attenuator is installed at the sample feeding end of the microfluidic chip so as to achieve a rapid ultrasonic wave intensity decline in a short distance, so that an interfacial tension difference can be formed at both ends of the chip, and a sample flow is facilitated to flow along an originally-hydrophobic capillary channel to the direction of the terminal.

Description

technical field

[0001] The invention relates to a device for AIDS diagnosis with easily removable components for driving liquid flow, which belongs to the field of analysis and testing. Background technique

[0002] For the background of multi-channel microfluidic AIDS diagnosis technology, please refer to CN 200910151219.0 and other invention patent applications.

[0003] As far as the overall overview of microfluidic technology itself is concerned, you can refer to the monograph "Illustrated Microfluidic Chip Laboratory" published by the famous microfluidic expert Mr. Lin Bingcheng not long ago, which has been published by Science Press. The past, present, and future prospects of microfluidic technology, etc., have detailed and long-form discussions that go deep into specific details.

[0004] So, let's talk about the key issues of this case.

[0005] The basic structure of a microfluidic chip includes a substrate etched with tiny liquid flow channels and a cover sheet a...

Examples

Embodiment Construction

[0071] exist figure 1 and figure 2In the shown embodiment of the present case, the structure of the device includes a multi-channel microfluidic chip, and the structure of the microfluidic chip includes a substrate 19 and a cover sheet 20 that are attached to each other and installed together. The substrate 19 and the cover sheet 20 are plates or sheets, the surface of the substrate 19 facing the cover sheet 20 contains a groove structure formed by a molding process or an etching process, and the substrate 19 also contains a channel structure that is connected to the groove The window structure is connected with the channel structure and penetrates the substrate through a molding process, an etching process or a simple punching process. The substrate 19 and the cover sheet 20 that are attached to each other are jointly constructed to form a channel structure and a window structure. A microfluidic chip with a liquid pool structure connected to it, the liquid pools are liquid ...

technical field

[0001] The invention relates to a device for AIDS diagnosis with easily removable components for driving liquid flow, which belongs to the field of analysis and testing. Background technique

[0002] For the background of multi-channel microfluidic AIDS diagnosis technology, please refer to CN 200910151219.0 and other invention patent applications.

[0003] As far as the overall overview of microfluidic technology itself is concerned, you can refer to the monograph "Illustrated Microfluidic Chip Laboratory" published by the famous microfluidic expert Mr. Lin Bingcheng not long ago, which has been published by Science Press. The past, present, and future prospects of microfluidic technology, etc., have detailed and long-form discussions that go deep into specific details.

[0004] So, let's talk about the key issues of this case.

[0005] The basic structure of a microfluidic chip includes a substrate etched with tiny liquid flow channels and a cover sheet a...

Examples

Embodiment Construction

[0071] exist figure 1 and figure 2In the shown embodiment of the present case, the structure of the device includes a multi-channel microfluidic chip, and the structure of the microfluidic chip includes a substrate 19 and a cover sheet 20 that are attached to each other and installed together. The substrate 19 and the cover sheet 20 are plates or sheets, the surface of the substrate 19 facing the cover sheet 20 contains a groove structure formed by a molding process or an etching process, and the substrate 19 also contains a channel structure that is connected to the groove The window structure is connected with the channel structure and penetrates the substrate through a molding process, an etching process or a simple punching process. The substrate 19 and the cover sheet 20 that are attached to each other are jointly constructed to form a channel structure and a window structure. A microfluidic chip with a liquid pool structure connected to it, the liquid pools are liquid ...

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