A quantitative plasma collection disc

Through the design of a quantitative plasma collection disc, which integrates the introduction and quantification functions and uses centrifugal force to achieve accurate quantification of plasma, the problems of high cost and complex operation of traditional blood testing equipment are solved, and low-cost and efficient blood testing is achieved.

CN108444803BActive Publication Date: 2025-09-30SHIJIAZHUANG HIPRO BIOTECH
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Patent Information

Application Number
CN201810450269.8
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2018-05-11
Publication Date
2025-09-30
Estimated Expiration
2038-05-11

AI Technical Summary

Technical Problem

Traditional blood testing equipment has high procurement costs, complex operations, many error factors and is difficult to popularize in general hospitals, especially when there are many blood test parameters.

Method used

A quantitative plasma collection disc is used, which is a plastic disc integrating the functions of introduction, quantification and overflow. It achieves accurate quantification of plasma through centrifugal force and is combined with special centrifugal operation equipment to simplify the operation process.

Benefits of technology

It reduces detection costs, improves operational efficiency, reduces errors, avoids contamination risks, and is suitable for large-scale production and wide application.

✦ Generated by Eureka AI based on patent content.

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Abstract

The present invention discloses a quantitative plasma collection optical disc, comprising an optical disc, an introduction device disposed on the optical disc, and a quantitative device disposed on the optical disc; the introduction device comprises an introduction tube, a shunt tube connected to the introduction tube, a check tube connected to the shunt tube, and an output tube connected to the check tube; the quantitative device comprises a quantitative pool and an overflow pool; the input end of the quantitative pool is connected to the shunt tube; and the output end of the quantitative pool is connected to the overflow pool. The present invention employs an integrated design, capable of completing tasks such as quantitative collection and storage, and coordinating subsequent testing, effectively shortening blood testing time and reducing testing costs, thereby providing patients with higher-quality medical services.
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Description

Technical Field

[0001] The present invention relates to the field of blood testing, and in particular to a quantitative plasma collection optical disc. Background Art

[0002] Clinical blood tests can be divided into general blood tests, laboratory tests for hemolytic anemia, bone marrow cytology tests, blood typing and cross-matching tests. They can detect hematological signs of common blood diseases.

[0003] The most common blood test is a routine blood test (also known as a blood count). This tests and analyzes the quantity and quality of red blood cells, white blood cells, and platelets. For example, tests related to various diseases, such as blood disorders, require not only a routine blood count but also bone marrow cell testing and blood cell chemical staining analysis. For patients with liver and kidney diseases, blood tests primarily include liver and kidney function tests. For some infectious diseases, blood antibody testing is a crucial diagnostic tool.

[0004] Traditional testing methods rely on testing for specific indicators or substances after sample collection. These methods are characterized by complex testing procedures, requiring multiple people and multiple devices, long testing times, and high costs. Especially in cases where reagents are required, various interfering factors, such as sample error, tool error, and human error, can affect test results. Although the adoption of automated testing equipment has accelerated significantly in recent years, the procurement costs, often in the hundreds of thousands or even millions of yuan, are prohibitive for typical hospitals and testing institutions. This trend is exacerbated by the numerous parameters of blood tests and the inherently specialized nature of the testing equipment. Summary of the Invention

[0005] The present invention aims to provide a quantitative plasma collection optical disc which is easy to use.

[0006] The present invention adopts the following technical solutions:

[0007] A quantitative plasma collection optical disc, comprising an optical disc, an introduction device arranged on the optical disc, and a quantitative device arranged on the optical disc;

[0008] The introduction device includes an introduction pipe, a shunt pipe connected to the introduction pipe, a check pipe connected to the shunt pipe, and an outlet pipe connected to the check pipe;

[0009] The quantitative device includes a quantitative tank and an overflow tank;

[0010] The input end of the quantitative pool is connected to the shunt pipe; the output end of the quantitative pool is connected to the overflow pool.

[0011] As a further solution: the quantitative pool is located on a side of the shunt tube close to the center of the optical disc.

[0012] As a further solution: the overflow tank is located on the side of the quantitative tank close to the center of the optical disc.

[0013] As a further solution: the overflow pool includes pool A and pool B connected to pool A;

[0014] The pool B is located on the side of the pool A close to the quantitative pool;

[0015] The output end of the quantitative cell is connected to cell A.

[0016] As a further solution: a transition section A is provided at the connection between the check pipe and the outlet pipe;

[0017] The minimum distance between the transition section and the center of the optical disc is smaller than the minimum distance between the overflow pool and the center of the optical disc.

[0018] As a further solution: a transition section B is provided at the connection between the inlet pipe and the diversion pipe.

[0019] As a further solution: a transition section C is provided at the connection between the diverter pipe and the check pipe.

[0020] The positive effects produced by the present invention are as follows:

[0021] The present invention is more convenient to use. When plasma quantification is required, a certain amount of plasma is injected through the introduction tube. As the optical disc rotates, the plasma begins to flow along the introduction tube. At this time, the air pressure in the check tube is greater than the air pressure at the connection between the quantitative pool and the shunt tube. The plasma flows into the quantitative pool, and the excess part flows into the overflow pool. The overflow pool is divided into two parts, pool A and pool B. The excess plasma first flows into pool A, and then flows into pool B under the action of centrifugal force. The amount of injected plasma is strictly controlled to ensure that there is no residue in pool A. Then, the optical disc rotates in the opposite direction, and the plasma in pool B cannot escape. The plasma in the quantitative pool flows out under the action of centrifugal force, flows along the shunt tube and the check tube to the outlet tube, and finally flows from the outlet tube to the subsequent mixing or detection part. Used in conjunction with a dedicated quantitative plasma pool, the present invention can perform plasma quantification operations quickly and accurately.

[0022] The carrier used in the present invention is a plastic optical disc, which can quickly reduce the manufacturing cost of the optical disc under a large-scale production model, thereby reducing the procurement cost of hospitals and other user institutions, so that more people can receive medical services.

[0023] Current plasma quantification requires multiple steps, including collection, separation, and quantification, requiring the use of various tools and equipment, resulting in high costs and time. However, the present invention allows for plasma quantification using only a single CD, saving significant time and tool consumption, shortening testing time, and improving efficiency.

[0024] Conventional plasma separation procedures involve a large number of reusable tools and equipment, in addition to some disposable instruments. This poses the risk of contamination and cross-infection, and requires additional disinfection steps. However, this invention utilizes a disposable design, with all quantification and derivation performed on a disc that is discarded after use, completely eliminating the possibility of sample contamination. BRIEF DESCRIPTION OF THE DRAWINGS

[0025] Figure 1 It is a structural schematic diagram of the present invention;

[0026] Among them: 11 inlet pipe, 12 diversion pipe, 13 check pipe, 14 outlet pipe, 21 quantitative pool, 22 pool A, 23 pool B, 3 transition section A, 4 transition section B, 5 transition section C. DETAILED DESCRIPTION

[0027] The following combination Figure 1 To further illustrate the present invention.

[0028] The present invention adopts the following technical solutions:

[0029] A quantitative plasma collection optical disc, comprising an optical disc, an introduction device arranged on the optical disc, and a quantitative device arranged on the optical disc;

[0030] The introduction device includes an introduction pipe 11, a shunt pipe 12 connected to the introduction pipe 11, a check pipe 13 connected to the shunt pipe 12, and an outlet pipe 14 connected to the check pipe 13;

[0031] The quantitative device includes a quantitative tank 21 and an overflow tank;

[0032] The input end of the quantitative pool 21 is connected to the shunt pipe 12 ; the output end of the quantitative pool 21 is connected to the overflow pool.

[0033] As a further solution: the quantitative pool 21 is located on a side of the shunt tube 12 close to the center of the optical disc.

[0034] As a further solution: the overflow tank is located on a side of the quantitative tank 21 close to the center of the optical disc.

[0035] As a further solution: the overflow pool includes pool A22 and pool B23 connected to pool A22;

[0036] The pool B23 is located on the side of the pool A22 close to the quantitative pool 21;

[0037] The output end of the quantitative cell 21 is connected to the cell A22.

[0038] As a further solution: a transition section A3 is provided at the connection between the check pipe 13 and the outlet pipe 14;

[0039] The minimum distance between the transition section 3 and the center of the optical disc is smaller than the minimum distance between the overflow pool and the center of the optical disc.

[0040] As a further solution: a transition section B4 is provided at the connection between the inlet pipe 11 and the diversion pipe 12 .

[0041] As a further solution, a transition section C5 is provided at the connection between the diverter pipe 12 and the check pipe 13 .

[0042] The structure and use of the present invention will be further described below in conjunction with actual operation processes.

[0043] The present invention requires a dedicated centrifugal operation device, which stores the rotation time and rotation speed required for each operation of the optical disc. The centrifugal operation device is not within the scope of protection of this application and is therefore not described in detail.

[0044] The optical disc mentioned in the present invention is made of polymer plastic, the quantitative tank 21 and the overflow tank are made by molding, and the inlet pipe 11, the shunt pipe 12, the check pipe 13 and the outlet pipe 14 are made by precision molding or etching and are integrated on a disc.

[0045] During use, the optical disc is placed on a centrifugal device and plasma is injected into an inlet tube 11. To further enhance operational convenience and integration, a quantitative plasma pool can be added to the optical disc. This pool is connected to the inlet tube 11. When plasma is injected into the pool, the centrifugal force causes the plasma inside the pool to flow into the inlet tube 11 as the optical disc rotates.

[0046] Under the action of centrifugal force, the plasma in the inlet tube 11 flows into the shunt tube 12, which is connected to the quantitative reservoir 21 and the check tube 13. With the help of the transition section A3, the gas pressure at the connection between the check tube 13 and the shunt tube 12 is greater than the gas pressure at the connection between the quantitative reservoir 21 and the shunt tube 12, so that all the plasma flows into the quantitative reservoir 21.

[0047] Here's a further explanation of gas pressure: The diameter of the connection between shunt tube 12 and metering pool 21 is similar to that of check tube 13. When the disc initially rotates, both contain air. Therefore, referring to the liquid pressure formula P = ρgh, when the length of check tube 13 is greater than the maximum distance between pool A22 and shunt tube 12, the gas pressure at the connection between check tube 13 and shunt tube 12 will be greater than the gas pressure at the connection between metering pool 21 and shunt tube 12. To ensure this pressure, during actual production, the length of check tube 13 is significantly greater than the maximum distance between pool A22 and shunt tube 12.

[0048] The plasma fills quantitative pool 21, and the excess flows into pool A22. Under the action of centrifugal force, the liquid in pool A22 flows into pool B23, while ensuring that no plasma remains in pool A22. This process can only be guaranteed when the plasma injection amount or the volume of the quantitative plasma pool is less than the sum of the volumes of quantitative pool 2 and pool B23 and greater than the volume of quantitative pool 21. Therefore, the plasma injection amount or the quantitative plasma pool must be strictly controlled.

[0049] The disc then rotates in the reverse direction, and the plasma in reservoir B23 remains stationary. The plasma in quantitative reservoir 21 flows out, then flows into check tube 13 and finally out of outlet tube 14. When the disc rotates in the reverse direction, in that direction of rotation, check tube 13 is located behind quantitative reservoir 21, and outlet tube 14 is located behind check tube 13. Since the relative motion of the plasma is opposite to the direction of disc rotation, it flows into check tube 13 and outlet tube 14 instead of into inlet tube 11.

[0050] The rear of the introduction tube 11 can be connected to a plasma storage pool or a reaction pool to detect the quantified plasma or to detect it in combination with reagents.

[0051] The transition section A3, the transition section B4 and the transition section C5 have the same function, which is to make the flow of plasma smoother.

[0052] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit it. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the aforementioned embodiments, or make equivalent replacements for some of the technical features therein, and these modifications or replacements do not cause the essence of the corresponding technical solutions to deviate from the spirit and scope of the technical solutions of the embodiments of the present invention.

Claims

1. A quantitative plasma collection optical disc, characterized by: The invention comprises an optical disc, an introduction device provided on the optical disc, and a quantitative device provided on the optical disc; the introduction device comprises an introduction pipe (11), a shunt pipe (12) connected to the introduction pipe (11), a check pipe (13) connected to the shunt pipe (12), and an outlet pipe (14) connected to the check pipe (13); the quantitative device comprises a quantitative pool (21) and an overflow pool; the input end of the quantitative pool (21) is connected to the shunt pipe (12); the output end of the quantitative pool (21) is connected to the overflow pool; The quantitative pool (21) is located on one side of the diversion tube (12) close to the center of the optical disc; The overflow tank is located on one side of the quantitative tank (21) close to the center of the optical disc; The overflow pool includes a pool A (22) and a pool B (23) connected to the pool A (22); the pool B (23) is located on a side of the pool A (22) close to the quantitative pool (21); the output end of the quantitative pool (21) is connected to the pool A (22); A transition section A (3) is provided at the connection between the check pipe (13) and the outlet pipe (14); the minimum distance between the transition section A (3) and the center of the optical disc is smaller than the minimum distance between the overflow tank and the center of the optical disc.

2. The quantitative plasma collection optical disc according to claim 1, characterized in that: A transition section B (4) is provided at the connection between the inlet pipe (11) and the diversion pipe (12).

3. The quantitative plasma collection optical disc according to claim 1, characterized in that: A transition section C (5) is provided at the connection between the diverter pipe (12) and the check pipe (13).

Citation Information

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