A hemodialyzer and a method for producing the same

Abstract

The present invention discloses a hemodialyzer, including an end cover, the end cover including a sealing ring and a cover body, a circle of grooves is arranged on the inner side surface of the cover body, the sealing ring includes a mounting portion and a sealing portion connected to the mounting portion, the mounting portion is arranged in the groove, the sealing portion extends out of the groove, the sealing ring and the cover body are integrally formed by in-mold inlay injection molding, the mounting portion is in an "I" shape, a connecting plane is arranged on the mounting portion, the sealing portion is connected to the connecting plane, and the connecting plane is flush with the inner side surface of the cover body. The structure of the present invention can avoid the risk of missing the sealing ring; and the in-mold inlay injection molding can play a role in error prevention, and the in-mold inlay injection molding also has the advantage of low cost; because the sealing ring is installed when the end cover is produced, the sealing ring can be inspected in multiple subsequent operation steps, which plays a further role in error prevention; the present invention also has the advantage that the connection between the sealing ring and the end cover is not easy to produce flash.

Description

Technical Field

[0001] The present invention relates to the field of medical devices, and in particular to a hemodialyzer and a production method thereof. Background Art

[0002] The hemodialyzer is a medical consumable for dialysis treatment of patients with renal failure. The hemodialyzer includes a shell, end caps arranged at both ends of the shell, and the end caps at both ends of the shell are respectively provided with a blood inlet and a blood outlet. The side of the shell is respectively provided with a dialysate inlet and a dialysate outlet near the two ends. A bundle of dialysate membranes is also arranged in the shell. Each unit of the dialysate membrane is in the shape of a hollow fiber. The dialysate membrane and the shell are connected by adhesive, and each dialysate membrane is also connected by adhesive. The adhesive is arranged at both ends of the shell. The glue separates the space in the shell from the space in the dialysate membrane, and the two ends of the dialysate membrane are connected to the space in the end cap. Blood enters from the blood inlet on the end cap, flows through the dialysate membrane, and then flows out through the blood outlet on the other end of the end cap; the dialysate flows in from the dialysate inlet on the shell and flows out from the dialysate outlet at the other end of the shell. In this process, the blood in the dialysate membrane and the dialysate in the shell penetrate each other, which plays a role in purifying blood. Since renal failure can cause damage to the bone marrow, patients with renal failure generally have anemia symptoms. Therefore, the blood of patients with renal failure is very precious, and the sealing performance of the hemodialyzer is therefore very important.

[0003] In the prior art, a sealing ring is generally provided between the end cap and the housing of the hemodialyzer to prevent blood from leaking from the contact portion between the end cap and the housing. In the production process of the hemodialyzer, a process of assembling the sealing ring and the end cap is generally included, which leads to the risk of missing the sealing ring. If the sealing ring is missing, a large amount of blood of the patient will leak from between the end cap and the housing, causing great harm to the patient.

[0004] The prior art also includes a process of leak detection on the dialysis membrane, but this process is performed without installing the end caps, so this process cannot detect whether the sealing ring is missing. If the dialysis membrane is leak-checked with the end caps installed, the ends of part of the dialysis membrane are covered by the sealing ring, and this part of the dialysis membrane cannot be detected. If the sealing ring is moved during use, blood will enter the undetected dialysis membrane, which will also cause the risk of blood leakage. Summary of the invention

[0005] The technical problem to be solved by the present invention is: in the prior art, there is a risk of missing a sealing ring during the production process of a hemodialyzer.

[0006] The solution of the present invention to solve its technical problem is:

[0007] A hemodialyzer comprises a shell and an end cover, wherein the end cover comprises a sealing ring and a cover body, a circle of grooves is provided on the inner side surface of the cover body, the sealing ring comprises a mounting portion and a sealing portion connected to the mounting portion, the mounting portion is provided in the groove, the sealing portion extends out of the groove, the sealing ring and the cover body are integrally formed by in-mold inlay injection molding, the mounting portion is in an "I" shape, a connecting plane is provided on the mounting portion, the sealing portion is connected to the connecting plane, and the connecting plane is flush with the inner side surface of the cover body.

[0008] As a further improvement of the above technical solution, the shell is cylindrical as a whole, and end covers are connected to both ends of the shell. A positioning protrusion is also provided on the shell, and a transition arc surface is provided on the side of the positioning protrusion close to the shell end, and a clamping plane is provided on the side of the positioning protrusion away from the shell end. A positioning hole is also provided on the inner side surface of the cover body, and the positioning protrusion is accommodated in the positioning hole. A clamping sub-plane is provided in the positioning hole, and the clamping sub-plane is parallel to the clamping plane and abuts against each other, and the end face of the shell abuts against the sealing portion.

[0009] As a further improvement of the above technical solution, a guide protrusion is further provided on the shell, and a guide groove is further provided on the inner side surface of the cover body. The guide groove extends to the end surface of the cover body, and the guide protrusion is accommodated in the guide groove.

[0010] As a further improvement of the above technical solution, a transition surface is further provided between the positioning protrusion and the end surface of the shell.

[0011] As a further improvement of the above technical solution, there are several positioning protrusions, and the several positioning protrusions are arranged at intervals along the length direction of the shell. The number of the positioning holes is consistent with the positioning protrusions, and the positions of the several positioning holes and the several positioning protrusions correspond one by one.

[0012] The present invention also provides a method for producing a hemodialyzer, which is used to produce the hemodialyzer, and is characterized by comprising the following steps:

[0013] S1. Place a bundle of dialysis membranes into a housing, and seal both ends of the dialysis membranes, so that both ends of the sealed dialysis membranes extend outside the housing, thereby obtaining a prototype of a hemodialyzer;

[0014] S2, placing the hemodialyzer prototype obtained in step S1 into a centrifuge, pouring the evenly mixed AB glue into the shell, and centrifuging for 1 to 20 minutes to obtain a primary product of the hemodialyzer;

[0015] S3, removing the excess AB glue and dialysis membrane at both ends of the hemodialyzer initial product obtained in S2 to obtain the hemodialyzer main body;

[0016] S4, performing a water leakage test on the hemodialyzer body obtained in S3;

[0017] S5, drying the main body of the hemodialyzer at a temperature of 50 to 100 degrees Celsius for 0.5 to 5 hours;

[0018] S6. Install the end caps on both ends of the hemodialyzer body.

[0019] As a further improvement of the above technical solution, both ends of the dialysis membrane bundle after end-capping in step S1 extend 0.5-2 cm outside the shell.

[0020] As a further improvement of the above technical solution, the material of the dialysis membrane bundle in step S1 is polyarylsulfone or polyethersulfone, and the end-capping temperature is 280-350 degrees Celsius.

[0021] The present invention also proposes a hemodialyzer sealing device, which is used to realize the above-mentioned hemodialyzer production method, including a main motor, an auxiliary motor, a temperature control device, a vibration device, and a cutter. The cutter is electrically connected to the temperature control device, an anti-stick coating is provided on the right side surface of the cutter, a transversely arranged rack is fixed on the lower side of the cutter, the rack is transmission-connected to the auxiliary motor, the vibration device is electrically connected to the auxiliary motor, the vibration device abuts against the cutter, and the vibration device causes the cutter to vibrate in the up and down directions.

[0022] As a further improvement of the above technical solution, the tool is in the shape of a transversely arranged tube, the left end of the tool is provided with an opening, the right end of the tool is closed, and a cavity is provided in the tool. The vibration device includes a transversely arranged connecting rod and a vertically arranged disc cam, the disc cam is transmission-connected to the right end of the connecting rod, the disc cam is arranged in the cavity, the upper end of the disc cam abuts against the tool, the left end of the connecting rod extends out of the cavity, the left end of the connecting rod is transmission-connected to the main motor, and the main motor is arranged outside the cavity.

[0023] The beneficial effects of the present invention are:

[0024] By adopting the structure of the present invention, the step of installing the sealing ring during the assembly process of the hemodialyzer can be omitted, thereby avoiding the risk of missing the sealing ring.

[0025] The installation part is connected to the sealing part, and the installation part is arranged in the groove, so that the sealing ring is not easy to fall off from the cover body, thereby avoiding the situation that the sealing ring falls off during the installation process;

[0026] Compared with double-material injection molding, in-mold injection molding has the advantages of simple injection molding machine structure, simple injection molding process, low scrap rate and low cost;

[0027] Furthermore, if the sealing ring is not installed during injection molding, the space of the sealing part is filled with the injection plastic. As long as the space of the clamping sealing part is not provided with a draft angle, the end cap is difficult to remove from the injection molding machine, thus playing a role in preventing mistakes.

[0028] End caps are usually purchased from injection molding companies and then sent back to medical device companies. During this process, injection molding personnel can check the caps without sealing rings. In addition, injection molding companies can also inspect end caps before they leave the factory, and medical device companies can also inspect end caps before they enter the factory. Operators of medical device companies can also inspect end caps when installing them. In this way, multi-level inspection steps play a further role in preventing errors.

[0029] During the in-mold injection molding process of the end cap, the plastic melt needs to flow through the gap between the connecting plane and the mold to reach the sealing part. In order to make the sealing part easily connected to the mold core, the gap between the sealing part and the mold core is larger. If the gap between the sealing part and the mold core contacts the plastic melt, flash will be easily generated. Setting a connecting plane can avoid this situation. The injection pressure will press the connecting plane against the mold core, which has the advantage of not easily generating flash. BRIEF DESCRIPTION OF THE DRAWINGS

[0030] In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the following briefly describes the drawings required for use in the description of the embodiments. Obviously, the drawings described are only part of the embodiments of the present invention, not all of the embodiments, and those skilled in the art can also obtain other design solutions and drawings based on these drawings without creative work.

[0031] Figure 1 is a schematic diagram of an end cover according to a first embodiment of the present invention;

[0032] Figure 2 is a schematic diagram of the injection molding principle of the end cap of the first embodiment of the present invention;

[0033] Figure 3 yes Figure 2 A partial enlarged view of

[0034] Figure 4 is a schematic diagram of an end cover according to a second embodiment of the present invention;

[0035] Figure 5 is a schematic diagram of the injection molding of the end cap of the second embodiment of the present invention;

[0036] Figure 6 yes Figure 5 A partial enlarged view of

[0037] Figure 7 is a schematic diagram of an end cap of the present invention;

[0038] Figure 8It is a schematic diagram of the assembly of the end cover and the housing of the present invention;

[0039] Fig. 9 is a cross-sectional view of a hemodialyzer end-sealing device of the present invention;

[0040] Fig.10 Schematic diagram of the rack of the present invention. DETAILED DESCRIPTION

[0041] The following will clearly and completely describe the concept, specific structure and technical effects of the present invention in combination with the embodiments and drawings, so as to fully understand the purpose, characteristics and effects of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of them. Based on the embodiments of the present invention, other embodiments obtained by technicians in this field without creative work are all within the scope of protection of the present invention. In addition, all the connection relationships mentioned in the text do not refer to the direct connection of components, but refer to the fact that a better connection structure can be formed by adding or reducing connecting accessories according to the specific implementation situation. The various technical features in the invention can be combined interchangeably without conflicting with each other.

[0042] Reference Figures 1 to 3 ,as well as Figures 7 to 10 , which is Embodiment 1 of the present invention, specifically:

[0043] A hemodialyzer comprises an end cover, wherein the end cover comprises a sealing ring and a cover body 12, a circle of grooves is provided on the inner side surface of the cover body 12, the sealing ring comprises a mounting portion 10 and a sealing portion 11 connected to the mounting portion 10, the mounting portion 10 is arranged in the groove, the sealing portion 11 extends out of the groove, the sealing ring and the cover body 12 are integrally formed by in-mold inlay injection molding, the mounting portion 10 is in an "I" shape, a connecting plane 17 is provided on the mounting portion 10, the sealing portion 11 is connected to the connecting plane 17, and the connecting plane 17 is flush with the inner side surface of the cover body 12.

[0044] In this embodiment, the groove is arranged at the top of the inner side of the cover body 12, and the sealing part 11 is connected to the lower side of the mounting part 10. By adopting the structure of the present invention, the step of installing the sealing ring during the assembly process of the hemodialyzer can be omitted, thereby avoiding the risk of missing the sealing ring. The mounting part 10 is connected to the sealing part 11, and the mounting part 10 is arranged in the groove, so that the sealing ring is not easy to fall off from the cover body 12, thereby avoiding the situation where the sealing ring falls during the installation process. The specific process of in-mold injection molding of the sealing ring and the cover body 12 is: after opening the mold, the sealing part 11 is clamped on the mold core, the mounting part 10 is exposed in the mold cavity, and then the mold is closed for injection molding. When the mold is opened again, the sealing ring and the cover body 12 have become one, and the end cover can be removed from the mold. Compared with double-material injection molding, in-mold injection molding has the advantages of simple injection molding machine structure, simple injection molding process, low scrap rate and low cost. Moreover, if the sealing ring is not installed during injection molding, the space of the sealing part 11 is filled with the injection material. As long as the space of the clamping sealing part 11 is not provided with a draft angle, the end cap is difficult to remove from the injection molding machine, thus playing a role in error prevention. The end cap is generally purchased from the injection molding company and returned to the medical device company. During the process, the injection molding personnel can check the cover body 12 without the sealing ring. Moreover, the injection molding company can also inspect the end cap before leaving the factory, and the medical device company can also inspect the end cap before entering the factory. The operators of the medical device company can also inspect the end cap when installing the end cap. In this way, the multi-level inspection steps can play a role in error prevention and prevent bleeding during use due to the lack of sealing ring installed in the end cap.

[0045] Reference Figure 2 and Figure 3 , the arrow represents the injection pressure. It can be seen that in this embodiment, during the in-mold injection molding process of the end cap, the plastic melt needs to flow through the gap between the connecting plane 17 and the mold to reach the sealing portion 11. In order to make the sealing portion 11 easily snap-fitted to the mold core, the gap between the sealing portion 11 and the mold core is relatively large. If the gap between the sealing portion 11 and the mold core contacts the plastic melt, flash will easily be generated. The connection plane 17 can avoid this situation. The injection pressure will press the connection plane 17 against the mold core, and flash will not easily be generated at the joint between the connection plane 17 and the mold core.

[0046] Furthermore, it also includes a shell that is cylindrical as a whole, and end covers are connected to both ends of the shell. A positioning protrusion 23 is also provided on the shell. A transition arc surface 231 is provided on the side of the positioning protrusion 23 close to the shell end, and a clamping plane 232 is provided on the side of the positioning protrusion 23 away from the shell end. A positioning hole 14 is also provided on the inner side surface of the cover body 12, and the positioning protrusion 23 is accommodated in the positioning hole 14. A clamping sub-plane 15 is provided in the positioning hole 14, and the clamping sub-plane 15 is parallel to the clamping plane 232 and abuts against each other, and the end face of the shell abuts against the sealing portion.

[0047] The connection between the positioning protrusion 23 and the positioning hole 14 is a one-way snap-fit ​​structure. The end cap can only move inward from the end of the shell and be pressed against the shell, but the end cap cannot be removed from the shell in the opposite direction unless the above-mentioned snap-fit ​​structure is destroyed. In the prior art, a threaded connection is usually used between the end cap and the shell. Due to the error in the force applied by the operator, the degree of tightening of the thread is difficult to control, and the friction force of the threaded connection needs to be tested for each product. With a one-way snap-fit, the snap-fit ​​force of each product is almost the same, and there is no need to test each product, which improves the production rhythm. The structure is reliably connected, cannot be disassembled, will not loosen during transportation, and has a reliable sealing effect.

[0048] Furthermore, the housing is provided with a guide protrusion 22, and the inner side of the cover body 12 is provided with a guide groove 16, the guide groove 16 extends to the end surface of the cover body 12, and the guide protrusion 22 is accommodated in the guide groove 16. Due to the clamping connection between the end cover and the housing, the positioning protrusion 23 and the positioning hole 14 need to be aligned, so the guide groove 16 and the guide protrusion 22 are provided to facilitate assembly.

[0049] Furthermore, a transition surface 21 is provided between the positioning protrusion 23 and the end surface of the housing. The transition surface 21 may be an inclined surface or an arc surface, and the function of the transition surface 21 is to make the end of the housing slide into the end cover more easily.

[0050] Furthermore, there are several positioning protrusions 23, which are arranged at intervals along the length direction of the housing, and the number of positioning holes 14 is consistent with the positioning protrusions 23, and the positions of the positioning holes 14 and the positioning protrusions 23 correspond one to one. The above is a multi-stage snap connection, which can improve the reliability of the snap connection.

[0051] The present invention also provides a method for producing a hemodialyzer, which is used to produce the above-mentioned hemodialyzer, comprising the following steps:

[0052] S1, placing a bundle of dialysis membranes into a housing, and sealing both ends of the dialysis membranes, so that both ends of the sealed dialysis membranes extend outside the housing, and a hemodialyzer prototype is obtained; in the subsequent S3, after cutting off the excess AB glue at both ends of the initial product of the hemodialyzer, the two ends of the dialysis membranes should be connected to the outside, so in this step, both ends of the dialysis membranes extend outside the housing;

[0053] S2, placing the hemodialyzer prototype obtained in step S1 into a centrifuge, pouring the evenly mixed AB glue into the shell, and centrifuging for 1 to 20 minutes to obtain a primary product of the hemodialyzer;

[0054] S3, removing the excess AB glue and dialysis membrane at both ends of the hemodialyzer initial product obtained in S2 to obtain the hemodialyzer main body;

[0055] S4, conduct a water leakage test on the main body of the hemodialyzer obtained in S3; fix the main body of the hemodialyzer obtained in S3 on a water leakage tester, the water leakage tester pours clean water at room temperature into the dialysis membrane from one end of the main body of the hemodialyzer, and the other end of the main body of the hemodialyzer is closed. The initial water pressure of the water leakage tester filling is certain. After a certain period of time, the water leakage tester will read the pressure at both ends of the main body of the hemodialyzer. If the pressure value read later differs from the initial water pressure filled by the water leakage tester within the specified range, the water leakage performance of the main body of the hemodialyzer is qualified. In the prior art, in some cases, the dialysis membrane is leak-tested with the end cover installed, then the end of the peripheral part of the dialysis membrane is covered by the sealing ring, and this part of the dialysis membrane cannot be detected. If the sealing ring position has moved during use, blood will enter the undetected dialysis membrane, which will cause the risk of blood leakage. Furthermore, the hemodialyzer equipped with end caps is not convenient for drying because the outlet area of ​​the airflow is small and both ends of part of the dialysis membrane are blocked by the sealing ring;

[0056] S5, drying the hemodialyzer body at a temperature of 50-100 degrees Celsius for 0.5-5 hours;

[0057] S6. Install the end caps at both ends of the hemodialysis machine body. Since the end caps of the present invention are connected to the housing by means of a snap-fit, the snap-fit ​​force of each product is almost the same, so there is no need to test the tightness of the installation after the end caps are installed, and they will not loosen during transportation. Only the damage of the snap-fit ​​structure will cause the snap-fit ​​to fail. In addition, when the snap-fit ​​structure is damaged, the end caps and the housing are loose and shaky, which can be easily discovered during use, so there will be no bleeding during use.

[0058] Furthermore, both ends of the dialysis membrane bundle after end-capping in step S1 extend 0.5 to 2 cm outside the shell. In the subsequent step S3, the excess AB glue and dialysis membrane at both ends of the hemodialysis machine initial product obtained in S2 are generally cut through rough cutting and fine cutting processes, and a length of 0.5 to 2 cm is reserved for easy cutting; and 0.5 to 2 cm is reserved at both ends, so the total reserved amount is 1 to 4 cm, and this length range is also easy to control for the operator responsible for step S1;

[0059] Furthermore, the material of the dialysis membrane bundle in step S1 is polyarylsulfone or polyethersulfone, and the end-capping temperature is 280-350 degrees Celsius. In the end-capping step in the production process of the hemodialyzer, the traditional process adopts the method of cutting the dialysis membrane with a heating resistor wire or a resistor sheet. The temperature of the resistor wire or the resistor sheet is generally 700-900 degrees Celsius. After cutting, part of the dialysis membrane has been carbonized, resulting in black ash on the production site. The hemodialyzer production workshop is a dust-free workshop, and the carbonized dialysis membrane black ash will pollute the product and the workshop environment. The melting point of polyarylsulfone or polyethersulfone is above 280 degrees Celsius. The temperature of the cutting tool is controlled by a temperature control device within the range of 280-350 degrees Celsius, and the end of the dialysis membrane is melted, and the end is sealed with the molten part. In this way, the generation of carbonized black ash can be avoided.

[0060] The present invention also proposes a hemodialyzer sealing device, which is used to realize the above-mentioned hemodialyzer production method, including a main motor 32, an auxiliary motor 33, a temperature control device 34, a vibration device, and a cutter 3. The cutter 3 is electrically connected to the temperature control device 34, and an anti-stick coating 31 is provided on the right side surface of the cutter 3. A transversely arranged rack 37 is fixed on the lower side of the cutter 3, and the rack 37 is transmission-connected to the main motor 32. The vibration device is electrically connected to the auxiliary motor 33, and the vibration device abuts against the cutter 3. The vibration device causes the cutter 3 to vibrate in the up and down directions.

[0061] The working principle of the hemodialyzer end-sealing device is as follows: the temperature of the cutter 3 is controlled by the temperature control device 34 to be near the melting point of the dialysis membrane, the end of a bundle of dialysis membrane is abutted against the right side of the cutter 3, the end of the dialysis membrane gradually melts, and under the action of the vibration device, the cutter 3 vibrates up and down, so that the end melt of the dialysis membrane moves in the up and down direction, and the cutter 3 moves to the right under the drive of the rack 37 and the main motor 32, pushing the melted part of the dialysis membrane to the right, so that the end of the dialysis membrane is sealed, and since the right side of the cutter 3 is provided with an anti-stick coating 31, the dialysis membrane after the end sealing can be removed from the cutter 3. The device has a simple structure, is practical and convenient, and does not produce black ash.

[0062] A main gear meshing with the rack 37 is provided below the rack 37, and the main gear is connected to the main motor 32 in a transmission manner to realize the transmission connection between the rack 37 and the main motor 32. A passive gear meshing with the main gear is provided on the left or right side of the main gear, and the passive gear meshes with the rack 37. In this way, there are at least two support points below the cutter 3, which can prevent the cutter 3 from shaking left and right. Since the stroke of the cutter 3 is generally less than 1 cm in the end-sealing process, the diameter of the main gear is within the range of 1 to 10 cm, and the structure of the passive gear is consistent with that of the active gear. For the convenience of control, a reduction box can also be provided between the main gear and the main motor 32. The right side of the cutter 3 is provided with evenly distributed protrusions. Since the adhesion between the anti-sticking coating 31 and the dialysis membrane is very small, when the cutter 3 vibrates up and down, the protrusion can play a role in disturbing the melt of the dialysis membrane in the up and down directions, so that the melt vibrates up and down with the cutter 3, thereby ensuring the sealing effect of the end-sealing. In addition, the temperature control device 34 includes a heating device, a heat dissipation device, a temperature sensor, and a control unit. There are many specific technical solutions for the temperature control device 34 in the prior art. The technicians in this field can select the existing temperature control device 34 to connect with the tool 3 of the present invention to realize the temperature control function. The technicians in this field know the specific connection method of the temperature control device 34 and the tool 3 of the present invention. The supplier of the temperature control device 34 can also provide the connection method. Since the working temperature of the tool 3 is 280-350 degrees Celsius, and the temperature of the production workshop is about 26 degrees Celsius, in order to better control the temperature, avoid heat dissipation, and save energy, a variety of insulation structures can be set. For example: the lower surface of the rack is provided with an insulation material layer, and the insulation material layer can reduce the heat of the tool 3 to the main gear and the main motor 32. The insulation material layer adopts wool felt, and the wool felt is bonded to the lower side of the rack. The wool felt has the functions of wear resistance and heat preservation. In addition, the outer and inner sides of the side wall of the tool 3 are provided with insulation coatings, and the temperature control device 34 is connected to the left end of the tool 3. In this way, the heat of the tool 3 can be reduced from being transferred to the vibration device.

[0063] Further, the tool 3 is in a cylindrical shape arranged horizontally, the left end of the tool 3 is provided with an opening, the right end of the tool 3 is closed, a cavity is provided in the tool 3, the vibration device comprises a connecting rod 35 arranged horizontally, and a disc cam 36 arranged vertically, the disc cam 36 is transmission-connected with the right end of the connecting rod 35, the disc cam 36 is arranged in the cavity, the upper end of the disc cam 36 abuts against the tool 3, the left end of the connecting rod 35 extends out of the cavity, the left end of the connecting rod 35 is transmission-connected with the auxiliary motor 33, and the main motor 32 is arranged outside the cavity. The working principle of this structure is that when the main motor 32 rotates, it drives the connecting rod 35 and the disc cam 36 to rotate, and when the disc cam 36 rotates, the position of its upper end changes regularly in the vertical plane, and because the upper end of the disc cam 36 abuts against the tool 3, the tool 3 vibrates in the vertical direction. The device has a simple structure and low cost.

[0064] Since the tool 3 moves to the right while vibrating in the up-down direction, the disc cam 36 will generate a spiral track on the inner wall of the tool 3. The smoother the inner wall of the tool 3 is, the smoother the relative movement between the disc cam 36 and the tool 3 is. In order to reduce the requirement for the overall smoothness of the inner wall of the tool 3, the inner side of the tool 3 is provided with a spiral groove, and the disc cam 36 abuts against the spiral groove. The spiral groove can be made by precision lathe machining, which is convenient and low in cost. At the same time, the spiral groove is also good for increasing the stability of the tool 3. The left and right sides of the spiral groove abut against the left and right sides of the disc cam 36, which can prevent the tool 3 from shaking left and right. In order to make the cam rotate smoothly, the spiral groove is not provided with a thermal insulation coating, and the thermal insulation coating is sprayed before the spiral groove is machined. In this way, heat is easily transferred to the auxiliary motor 33 to the left. In order to reduce the heat loss of the cutter 3 and avoid the auxiliary motor 33 being in a high temperature state, which affects the life of the motor, a heat insulation material layer is provided on the connecting surface of the connecting rod 35 and the disc cam 36, so that heat is difficult to transfer to the auxiliary motor 33. The hemodialyzer sealing device also includes a transparent, boxed shell, a through hole is provided on the right side wall of the shell, the diameter of the through hole is smaller than the diameter of the cutter 3, and the through hole protrudes to the right or left. When the hemodialyzer sealing device is used, the dialysis membrane bundle extends from the through hole into the hemodialyzer sealing device and abuts against the anti-sticking coating 31, and the lower side of the dialysis membrane bundle can abut against the inner side of the through hole. The provision of the shell has the benefit of increasing the safety of the hemodialyzer sealing device, preventing production personnel from touching the main motor 32 and the auxiliary motor 33, as well as the high-temperature cutter 3, and preventing accidents such as scalding.

[0065] Reference Figure 4 , Figure 5 , Figure 6 , which is the second embodiment of the present invention, specifically:

[0066] The difference from the first embodiment is that the groove is provided on the side wall of the inner side of the cover body 12, the sealing portion 11 is connected to the inner side of the mounting portion 10, and correspondingly, the connecting plane 17 is also provided on the inner side of the sealing portion 11. The effects achieved by this embodiment are consistent with those achieved by the first embodiment.

[0067] The preferred embodiments of the present invention are specifically described above, but the invention is not limited to the embodiments. Those skilled in the art may make various equivalent modifications or substitutions without violating the spirit of the invention. These equivalent modifications or substitutions are all included in the scope defined by the claims of this application.

Claims

1. A capping device, characterized in that: The end-sealing device is used to implement a method for producing a hemodialyzer, comprising a main motor (32), an auxiliary motor (33), a temperature control device (34), a vibration device, and a cutter (3); the cutter (3) is electrically connected to the temperature control device (34); an anti-stick coating (31) is provided on the right side surface of the cutter (3); a transversely arranged rack (37) is fixedly provided on the lower side of the cutter (3); the rack (37) is transmission-connected to the main motor (32); the vibration device is transmission-connected to the auxiliary motor (33); the vibration device abuts against the cutter (3); and the vibration device causes the cutter (3) to vibrate in the up and down directions; The method for producing a hemodialyzer is used to produce a hemodialyzer, comprising the following steps: S1. Place a bundle of dialysis membranes into a housing, and seal both ends of the dialysis membranes, so that both ends of the sealed dialysis membranes extend outside the housing, thereby obtaining a prototype of a hemodialyzer; S2, placing the hemodialyzer prototype obtained in step S1 into a centrifuge, pouring the evenly mixed AB glue into the shell, and centrifuging for 1 to 20 minutes to obtain a primary product of the hemodialyzer; S3, removing the excess AB glue and dialysis membrane at both ends of the hemodialyzer primary product obtained in S2 to obtain the hemodialyzer body; S4, performing a water leakage test on the hemodialyzer body obtained in S3; S5, drying the main body of the hemodialyzer at a temperature of 50 to 100 degrees Celsius for 0.5 to 5 hours; S6. Install the end caps on both ends of the hemodialyzer body; The hemodialyzer comprises a shell and an end cover, the end cover comprising a sealing ring and a cover body (12), the inner side surface of the cover body (12) being provided with a circle of grooves, the sealing ring comprising a mounting portion (10) and a sealing portion (11) connected to the mounting portion (10), the mounting portion (10) being arranged in the groove, the sealing portion (11) extending out of the groove, the sealing ring and the cover body (12) being integrally formed by in-mold injection molding, the mounting portion (10) being in an "I" shape, the mounting portion (10) being provided with a connecting plane (17), the sealing portion (11) being connected to the connecting plane (17), and the connecting plane (17) being flush with the inner side surface of the cover body (12); The shell is cylindrical in shape as a whole. Both ends of the shell are connected to end covers. The shell is also provided with a positioning protrusion (23). A transition arc surface (231) is provided on the side of the positioning protrusion (23) close to the shell end. A clamping plane (232) is provided on the side of the positioning protrusion (23) away from the shell end. A positioning hole (14) is also provided on the inner side surface of the cover body (12). The positioning protrusion (23) is accommodated in the positioning hole (14). A clamping sub-plane (15) is provided in the positioning hole (14). The clamping sub-plane (15) is parallel to the clamping plane (232) and abuts against each other. The end surface of the shell abuts against the sealing portion (11).

2. A sealing device according to claim 1, characterized in that: The shell body is also provided with a guide protrusion (22), and the inner side surface of the cover body (12) is also provided with a guide groove (16), the guide groove (16) extending to the end surface of the cover body (12), and the guide protrusion (22) is accommodated in the guide groove (16).

3. A sealing device according to claim 2, characterized in that: A transition surface (21) is also provided between the positioning protrusion (23) and the end surface of the shell.

4. A sealing device according to claim 2, characterized in that: There are a plurality of positioning protrusions (23), and the plurality of positioning protrusions (23) are arranged at intervals along the length direction of the shell. The number of positioning holes (14) is consistent with the number of positioning protrusions (23), and the positions of the plurality of positioning holes (14) and the plurality of positioning protrusions (23) correspond one to one.

5. The end-capping device according to claim 1, characterized in that: Both ends of the dialysis membrane bundle after end-capping in step S1 extend 0.5-2 cm outside the shell.

6. The end-capping device according to claim 1, characterized in that: The material of the dialysis membrane bundle in step S1 is polyarylsulfone or polyethersulfone, and the end-capping temperature is 280-350 degrees Celsius.

7. The end-capping device according to claim 1, characterized in that: The tool (3) is in the shape of a tube arranged transversely, the left end of the tool (3) is provided with an opening, the right end of the tool (3) is closed, a cavity is provided in the tool (3), the vibration device comprises a transversely arranged connecting rod (35) and a vertically arranged disc cam (36), the disc cam (36) is transmission-connected to the right end of the connecting rod (35), the disc cam (36) is arranged in the cavity, the upper end of the disc cam (36) abuts against the tool (3), the left end of the connecting rod (35) extends out of the cavity, the left end of the connecting rod (35) is transmission-connected to the auxiliary motor (33), and the main motor (32) is arranged outside the cavity.

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