A 3D printed chute-type percutaneous tissue puncture guide plate

Abstract

The present invention relates to the field of medical devices, and particularly to a percutaneous tissue puncture guide plate and a construction method thereof. The present invention provides a construction method for a percutaneous tissue puncture guide plate model, including: providing a three-dimensional model of the puncture site; obtaining puncture point A based on puncture point O; obtaining puncture point B based on puncture point O and puncture point C; constructing a guide plate body based on puncture point A and puncture point B; constructing a sliding groove based on puncture point A and puncture point B; constructing a first puncture guiding member based on puncture point A; and constructing a second puncture guiding member based on puncture point B. The percutaneous tissue puncture guide plate provided by the present invention can guide the puncture surgery for deep-lying parts, take into account the surgical approach, reduce the pollution of surrounding tissues, reduce intraoperative fluoroscopy, reduce the puncture failure rate, assist in the precise positioning of tumor lesions during the operation, provide convenience for puncture, shorten the puncture time, and has good industrialization prospects.

Description

Technical Field

[0001] The present invention relates to the field of medical devices, and particularly to a percutaneous tissue puncture guide plate and a construction method thereof. Background Art

[0002] Clinically, percutaneous biopsy of pelvic tumors is an important part of making a definite diagnosis and formulating a surgical plan, which is of great significance for guiding subsequent treatment. For tumors with large volume and superficial location in the pelvis, percutaneous biopsy is relatively simple. However, most tumors in the pelvic region are deep-seated, with complex anatomical sites (such as the acetabulum and the deep part of the ilium), adjacent to important surrounding blood vessels and nerves, and accurate percutaneous biopsy is not easy, often requiring precise preoperative planning and operation.

[0003] For such biopsy operations, currently, it is usually necessary to assist with imaging methods. Percutaneous biopsy under X-ray fluoroscopy is difficult to provide three-dimensional spatial information of the lesion and cannot accurately locate tumors in the pelvic region. CT-guided percutaneous biopsy operations are mostly used for lesions that are deeper, smaller in scope, or close to the blood vessel nerve bundle. Its disadvantages include that it can only guide puncture in the limited scanned section, restricting the biopsy path; the radiation dose is relatively large; restricted by the CT examination coil, it is not flexible to operate during puncture of patients with a relatively large body build, the pelvis and other regions. MRI has the advantages of high soft tissue contrast, multi-planar imaging, accurate positioning, and no radiation. However, due to the lack of corresponding specific supporting instruments for guiding bone biopsy, its clinical application is limited. Some other imaging technologies are still in the exploratory stage, with high requirements for imaging equipment and difficult to be clinically promoted. Summary of the Invention

[0004] In view of the above-mentioned disadvantages of the prior art, the purpose of the present invention is to provide a percutaneous tissue puncture guide plate and a construction method thereof to solve the problems in the prior art.

[0005] To achieve the above purpose and other related purposes, on the one hand, the present invention provides a construction method of a percutaneous tissue puncture guide plate model, including:

[0006] Providing a three-dimensional model of the part to be punctured, the three-dimensional model including a puncture point O and a target puncture point C, the puncture point O being located on the surface of the cortical bone, and the puncture point C being located in the puncture target area;

[0007] Obtaining a puncture point A based on the puncture point O, the puncture point A being located on the outer edge of the iliac crest and 2 - 3 cm behind the anterior superior iliac spine;

[0008] Obtaining a puncture point B based on the puncture point O and the puncture point C, the puncture point B being the intersection of the connection line of the puncture point O and the puncture point C and the body surface;

[0009] Construct a guide plate body based on puncture points A and B. The guide plate body covers the skin surface. The guide plate body includes a first puncture hole and a second puncture hole, and the positions of the first puncture hole and the second puncture hole are respectively matched with the positions of puncture points A and B.

[0010] Construct a sliding groove based on puncture points A and B. The sliding groove is located on the guide plate body and connects the first puncture hole and the second puncture hole.

[0011] Construct a first puncture guiding member based on puncture point A. The extending direction of the first puncture guiding member is consistent with the line connecting puncture points A and O. An opening is provided on the side of the first puncture guiding member facing the sliding groove.

[0012] Construct a second puncture guiding member based on puncture point B. The extending direction of the second puncture guiding member is consistent with the line connecting puncture points C and O. An opening is provided on the side of the second puncture guiding member facing the sliding groove.

[0013] In some embodiments of the present invention, the tissue is selected from pelvic tissues.

[0014] In some embodiments of the present invention, the tissue is selected from diseased tissues, preferably tumor tissues.

[0015] In some embodiments of the present invention, the puncture point O is located on the surface of the cortical bone at the acetabulum.

[0016] In some embodiments of the present invention, the specific method for constructing the guide plate body based on puncture points A and B is: construct a reference plane of the guide plate body based on the skin surface including puncture points A and B, and construct the guide plate body based on the reference plane of the guide plate body.

[0017] In some embodiments of the present invention, the guide plate body extends to the bone landmark points on the body surface. Preferably, the bone landmark points are selected from the combination of one or more of the anterior superior iliac spine, the greater trochanter of the femur, and the inguinal region.

[0018] In some embodiments of the present invention, the thickness of the guide plate body is 2 mm to 3 mm.

[0019] In some embodiments of the present invention, it further includes constructing a bone landmark fitting portion based on the bone landmark points. Preferably, the bone landmark fitting portion is selected from the anterior superior iliac spine fitting portion, the greater trochanter of the femur fitting portion, and the inguinal region fitting portion.

[0020] In some embodiments of the present invention, the aperture of the first puncture hole is 3 to 5 mm, and the aperture of the second puncture hole is 3 to 5 mm.

[0021] In some embodiments of the present invention, the length of the first puncture guide is 10 - 20 mm, and the length of the second puncture guide is 10 - 20 mm.

[0022] In some embodiments of the present invention, the included angle between the first puncture guide and the second puncture guide is 15 - 45°.

[0023] In some embodiments of the present invention, the size of the sliding groove is adapted to the first puncture hole and / or the second puncture hole.

[0024] In some embodiments of the present invention, the sliding groove extends linearly.

[0025] On the other hand, the present invention provides a method for preparing a percutaneous tissue puncture guide plate, the method comprising: preparing a percutaneous tissue puncture guide plate according to the percutaneous tissue puncture guide plate model constructed by the construction method of the percutaneous tissue puncture guide plate model.

[0026] On the other hand, the present invention provides a percutaneous tissue puncture guide plate, which is constructed by the construction method of the percutaneous tissue puncture guide plate model or prepared by the preparation method of the percutaneous tissue puncture guide plate.

[0027] On the other hand, the present invention provides a computer-readable storage medium, on which a computer program is stored, and when the program is executed by a processor, the steps of the construction method of the percutaneous tissue puncture guide plate model or the steps of the preparation method of the percutaneous tissue puncture guide plate are realized.

[0028] On the other hand, the present invention provides a device, comprising: a processor and a memory, the memory is used for storing a computer program, and the processor is used for executing the computer program stored in the memory, so that the device executes the steps of the construction method of the percutaneous tissue puncture guide plate model or the steps of the preparation method of the percutaneous tissue puncture guide plate model.

[0029] On the other hand, the present invention provides a device, the device may include:

[0030] A three-dimensional model providing module, configured to provide a three-dimensional model of the part to be punctured, the three-dimensional model including a puncture point O and a target puncture point C, the puncture point O is located on the surface of the pelvic acetabular cortical bone, and the puncture point C is located in the puncture target area;

[0031] A puncture point A obtaining module, configured to obtain a puncture point A based on the puncture point O, the puncture point A is located on the outer edge of the iliac crest and 2 - 3 cm behind the anterior superior iliac spine;

[0032] A puncture point B obtaining module, configured to obtain a puncture point B based on the puncture point O and the puncture point C, the puncture point B is the intersection of the connection line between the puncture point O and the puncture point C and the body surface;

[0033] The guide plate body construction module is used to construct the guide plate body based on the puncture point A and the puncture point B. The guide plate body covers the skin surface. The guide plate body includes a first puncture hole and a second puncture hole, and the positions of the first puncture hole and the second puncture hole are respectively matched with the positions of the puncture point A and the puncture point B.

[0034] The sliding groove construction module is used to construct a sliding groove on the guide plate body based on the puncture point A and the puncture point B. The sliding groove connects the first puncture hole and the second puncture hole.

[0035] The first puncture guide member construction module is used to construct a first puncture guide member based on the puncture point A. The extending direction of the first puncture guide member is consistent with the connection line between the puncture point A and the puncture point O.

[0036] The second puncture guide member construction module is used to construct a second puncture guide member based on the puncture point B. The extending direction of the second puncture guide member is consistent with the connection line between the puncture point C and the puncture point O.

[0037] Optionally, it further includes: the bony landmark fitting part construction module, which is used to construct the bony landmark fitting part based on the bony landmark. Preferably, the bony landmark fitting part is selected from the anterior superior iliac spine fitting part, the greater trochanter of femur fitting part, and the inguinal fitting part.

[0038] On the other hand, the present invention provides a percutaneous tissue puncture guide plate, which includes a guide plate body. The guide plate body further includes a first puncture hole, a second puncture hole, a sliding groove and a bony landmark fitting part. The sliding groove is located between the first puncture hole and the second puncture hole. The guide plate body is also provided with a first puncture guide member and a second puncture guide member. The position of the first puncture guide member is matched with the first puncture hole, and an opening is provided on the side of the first puncture guide member facing the sliding groove. The position of the second puncture guide member is matched with the second puncture hole, and an opening is provided on the side of the second puncture guide member facing the sliding groove.

[0039] In some embodiments of the present invention, the tissue is selected from pelvic lesion tissues.

[0040] In some embodiments of the present invention, the guide plate body includes a plurality of bony landmark fitting parts, and the bony landmark fitting parts include the anterior superior iliac spine fitting part, the greater trochanter of femur fitting part and the inguinal fitting part.

[0041] In some embodiments of the present invention, the thickness of the guide plate body is 2 mm to 3 mm.

[0042] In some embodiments of the present invention, the aperture of the first puncture hole is 3 to 5 mm, and the aperture of the second puncture hole is 3 to 5 mm.

[0043] In some embodiments of the present invention, the extending direction of the first puncture guide is consistent with the viewing direction of the outer plate of the ilium, and the intersection point of the extending direction of the first puncture guide and the extending direction of the second puncture guide is located on the surface of the pelvic acetabular cortical bone.

[0044] In some embodiments of the present invention, the length of the first puncture guide is 10 - 20 mm, and the length of the second puncture guide is 10 - 20 mm.

[0045] In some embodiments of the present invention, the included angle between the first puncture guide and the second puncture guide is 15 - 45°.

[0046] In some embodiments of the present invention, the size of the sliding groove is matched with the first puncture hole and / or the second puncture hole, and the sliding groove extends linearly.

[0047] In some embodiments of the present invention, the material of the puncture guide plate is photosensitive resin. Description of the Drawings

[0048] Figure 1 It shows a schematic structural diagram of the percutaneous tissue puncture guide plate of the present invention.

[0049] Figure 2 It shows a schematic construction diagram of the percutaneous tissue puncture guide plate of the present invention.

[0050] Figure 3 It shows a schematic usage diagram of the percutaneous tissue puncture guide plate of the present invention.

[0051] Description of Component Labels

[0052] 1 Guide plate body

[0053] 11 Bony landmark fitting part

[0054] 111 Anterior superior iliac spine fitting part

[0055] 112 Greater trochanter of femur fitting part

[0056] 113 Inguinal fitting part

[0057] 12 First puncture hole

[0058] 13 Second puncture hole

[0059] 14 Sliding groove

[0060] 2 First puncture guide

[0061] 3 Second puncture guide Detailed Description of the Invention

[0062] After a large amount of exploratory research, the inventors of the present invention provided a percutaneous tissue puncture guide plate and a construction method thereof. The percutaneous tissue puncture guide plate can utilize the extensibility of the skin, can achieve precise puncture of pelvic tumors, and provides a feasible method for precise biopsy of tumors in complex anatomical sites. On this basis, the present invention was completed.

[0063] In a first aspect of the present invention, a method for constructing a percutaneous tissue puncture guide plate model is provided, including:

[0064] S1) Provide a three-dimensional model of the part to be punctured, the three-dimensional model including a puncture point O and a target puncture point C, the puncture point O being located on the surface of the cortical bone, and the puncture point C being located in the puncture target area;

[0065] S2) Obtain a puncture point A based on the puncture point O, the puncture point A being located on the outer edge of the iliac crest and 2-3 cm behind the anterior superior iliac spine;

[0066] S3) Obtain a puncture point B based on the puncture point O and the puncture point C, the puncture point B being the intersection of the line connecting the puncture point O and the puncture point C and the body surface;

[0067] S4) Construct a guide plate body based on the puncture point A and the puncture point B, the guide plate body covering the skin surface, the guide plate body including a first puncture hole and a second puncture hole, the positions of the first puncture hole and the second puncture hole respectively corresponding to the positions of the puncture point A and the puncture point B;

[0068] S5) Construct a sliding groove based on the puncture point A and the puncture point B, the sliding groove being located on the guide plate body and connecting the first puncture hole and the second puncture hole;

[0069] S6) Construct a first puncture guiding member based on the puncture point A, the extending direction of the first puncture guiding member being consistent with the line connecting the puncture point A and the puncture point O, and an opening being provided on the side of the first puncture guiding member facing the sliding groove;

[0070] S7) Construct a second puncture guiding member based on the puncture point B, the extending direction of the second puncture guiding member being consistent with the line connecting the puncture point C and the puncture point O, and an opening being provided on the side of the second puncture guiding member facing the sliding groove.

[0071] The method for constructing a percutaneous tissue puncture guide plate model provided by the present invention may include: providing a three-dimensional model of the puncture site, the three-dimensional model including a puncture point O and a target puncture point C, the puncture point O being located on the surface of the cortical bone, and the puncture point C being located in the puncture target area. The percutaneous tissue puncture guide plate provided by the present invention can generally be directed at tissues that are small in volume and deep in location (usually diseased tissues, such as tumor tissues, etc.), for example, it can be a deep acetabular region. In the three-dimensional model, it generally includes the three-dimensional model of the patient's bones and the three-dimensional model of the surrounding tissues. The three-dimensional model of the bones generally includes parts such as the ilium, acetabulum, and ischium, and it can generally be obtained after importing CT data into software, specifically, for example, software such as Simplant, Mimics, and Proplan. The three-dimensional model of the surrounding tissues generally refers to the three-dimensional model of the relevant tissues around the patient's bones, and generally can include tumor diseased tissues, muscles, blood vessels (which can include the skin surface), and it can generally be obtained after importing CT data into software, specifically, for example, software such as mimics and medraw. After integrating the three-dimensional model of the bones and the three-dimensional model of the surrounding tissues, the overall three-dimensional model of the puncture site can be obtained, and the software used in the integration process can be, for example, software such as 3-matic and geomagic. In the three-dimensional model of the puncture site, the puncture point O is generally located on the surface of the cortical bone, so as to provide a certain fulcrum for the puncture needle when the puncture needle slides. For example, the puncture point O can be located on the surface of the cortical bone at the acetabulum in the pelvis. In the three-dimensional model of the puncture site, the puncture point C is generally located in the puncture target area, that is, corresponding to the tissue to be punctured and sampled. For example, the puncture point C can be located in the diseased tissue area, more specifically, it can be located in the tumor diseased area, preferably in the area with the strongest tumor diseased activity. The diseased area can generally be determined according to imaging. For example, the puncture point C can be located in the acetabular diseased area.

[0072] The method for constructing a percutaneous tissue puncture guide plate model provided by the present invention may further include: obtaining puncture point A based on puncture point O. Puncture point A is usually located on the outer edge of the iliac crest and 2-3 cm behind the anterior superior iliac spine. Puncture point A is usually located on the skin surface and at the point where the outer edge of the iliac crest can be clearly felt on the body surface. The line connecting puncture point O and puncture point A is usually consistent with the direction of the outer plate of the ilium (i.e., the outer side of the ilium), so as to avoid damaging tissues such as gluteal muscles, blood vessels and sciatic nerve. During puncture, the puncture needle can first enter from puncture point A and be guided to puncture point O, so as to form a certain support. In addition, the position where puncture point A is located usually corresponds to the subsequent surgical incision (ilioinguinal approach), and preferably can be located within the surgical incision, so that the puncture and the subsequent surgical incision are consistent, avoiding secondary injury. In the present invention, the puncture needle can be various puncture needles suitable for bone puncture. The puncture needle usually includes a puncture needle body extending linearly. A sleeve is sleeved outside the puncture needle body, and the two are in close contact. In a specific embodiment of the present invention, the puncture needle used can be a bone marrow biopsy needle (TSK, Japan), and the specification can be 8G or 11G, and the length can be 100 mm or 150 mm.

[0073] The method for constructing a percutaneous tissue puncture guide plate model provided by the present invention may further include: obtaining puncture point B based on puncture point O and puncture point C. Puncture point B is the intersection of the line connecting puncture point O and puncture point C and the body surface. Puncture point A is usually located on the skin surface. The lines connecting puncture point B, puncture point O and puncture point C usually correspond to the path for puncturing the target tissue during actual operation. However, on the path of the line connecting puncture point B and puncture point O, there are usually distributions such as tensor fasciae latae, gluteus medius and gluteus minimus and blood vessels. Therefore, during puncture, after the puncture needle is guided from the path of the line connecting puncture point O and puncture point A to puncture point O, the support of puncture point O and the ductility of the surrounding tissues can be utilized to slide the puncture needle from the path of the line connecting puncture point O and puncture point A to the path of the line connecting puncture point O and puncture point B. Subsequently, the cortical bone can be punctured by the puncture needle, the puncture needle body can be taken out and the sleeve is still maintained on the path of the line connecting puncture point O and puncture point B. Subsequently, the target area can be sampled through the sleeve.

[0074] The method for constructing a percutaneous tissue puncture guide plate model provided by the present invention may further include: constructing a guide plate body based on a puncture point A and a puncture point B. The guide plate body covers the skin surface. The guide plate body includes a first puncture hole and a second puncture hole for introducing a puncture needle and performing puncture. The positions of the first puncture hole and the second puncture hole respectively match the positions of the puncture point A and the puncture point B, and their sizes generally correspond to the size of the puncture needle (for example, the outer diameter of the sleeve of the puncture needle). For example, the aperture of the first puncture hole may be 3-5 mm, and for another example, the aperture of the second puncture hole is 3-5 mm. 2 The guide plate body is generally used to fit the skin surface, and through the puncture holes on its surface, it provides a basis for the puncture direction and ensures the stability of the puncture.

[0075] The method for constructing a percutaneous tissue puncture guide plate model provided by the present invention may further include: constructing a bony landmark fitting part based on bony landmarks. The guide plate body can generally extend to the bony landmarks on the body surface, thereby forming a bony landmark fitting part to facilitate accurately determining the fixing position of the guide plate. The bony landmarks on the body surface generally refer to the obvious protrusions or depressions formed on the body surface by the native land of certain parts of the human body. Generally speaking, the guide plate body can generally extend to multiple bony landmarks on the body surface, and multiple bony landmark fitting parts can be constructed based on the multiple bony landmarks to facilitate more accurate positioning. For example, the bony landmarks can be one or a combination of the anterior superior iliac spine, the greater trochanter of the femur, the groin, etc. For another example, the bony landmark fitting parts can be one or a combination of the anterior superior iliac spine fitting part, the greater trochanter of the femur fitting part, the groin fitting part, etc. Those skilled in the art can select the appropriate shape of the bony landmark fitting part. The shape of the bony landmark fitting part generally matches the body surface topography. For example, the bony landmark fitting part can be arranged around the bony landmark or cover part or all of the surface of the bony landmark.

[0076] In the present invention, the thickness of the guide plate body (including the bone landmark fitting portion) can be adjusted by those skilled in the art so as to provide appropriate support strength. For example, the thickness of the guide plate body can be 2 mm to 3 mm. In a preferred embodiment of the present invention, the specific method for constructing the guide plate body based on puncture point A and puncture point B is as follows: construct a reference plane of the guide plate body based on the skin surface including puncture point A and puncture point B, and construct the guide plate body based on the reference plane of the guide plate body. The reference plane of the guide plate body generally fits the body surface and can cover puncture point A and puncture point B. Preferably, the reference plane of the guide plate body can usually also extend to the surface of one or more bone landmarks, so as to provide a better fitting effect as a whole and provide a better guiding and supporting effect. Extend the reference plane of the guide plate body outward (i.e., the direction opposite to the direction facing the skin surface) by a certain distance, and the guide plate body can be constructed. The distance that the reference plane of the guide plate body extends outward is usually corresponding to the thickness of the guide plate body. For example, the extended distance can be 2 mm to 3 mm.

[0077] The method for constructing a percutaneous tissue puncture guide plate model provided by the present invention may further include: constructing a sliding groove based on puncture point A and puncture point B, and the sliding groove is located on the guide plate body and connects the first puncture hole and the second puncture hole. The sliding groove is generally used to realize the sliding of the puncture needle. As described above, after the puncture needle is led to puncture point O along the connection path between puncture point O and puncture point A, the support effect of puncture point O and the ductility of the surrounding tissues can be utilized, and through the sliding groove, the puncture needle can be slid from the connection path between puncture point O and puncture point A to the connection path between puncture point O and puncture point B. The size of the sliding groove generally matches the first puncture hole and / or the second puncture hole, so that the puncture needle can smoothly slide from the first puncture hole to the second puncture hole. The sliding groove preferably can extend linearly to avoid excessive movement of the patient's tissues. According to its extension direction, the length of the sliding groove can be 2 to 5 cm.

[0078] The method for constructing a percutaneous tissue puncture guide plate model provided by the present invention may further include: constructing a first puncture guide member based on puncture point A, wherein the extending direction of the first puncture guide member is consistent with the line connecting puncture point A and puncture point O, and an opening is provided on the side of the first puncture guide member facing the sliding groove. The first puncture guide member is generally used to guide the puncture needle to reach puncture point O along the route from puncture point A to puncture point O during the puncture process and form a certain support. The shape of the first puncture guide member generally matches the shape of the puncture needle (for example, the sleeve of the puncture needle), and it is generally a cylinder. The fact that an opening is provided on the side of the first puncture guide member facing the sliding groove generally means that the side wall of the first puncture guide member close to the sliding groove is missing, so that during puncture, the puncture needle can be guided by the columnar structure on one side thereof, and when the puncture needle needs to be slid, the size of the opening generally matches the sizes of the sliding groove and the puncture needle, so that the puncture needle can be removed from the opening of the first puncture guide member. The first puncture guide member has a certain length in its extending direction. For example, the length of the first puncture guide member can be 10-20 mm.

[0079] The method for constructing a percutaneous tissue puncture guide plate model provided by the present invention may further include: constructing a second puncture guide member based on puncture point B, wherein the extending direction of the second puncture guide member is consistent with the line connecting puncture point C and puncture point O, and an opening is provided on the side of the second puncture guide member facing the sliding groove. The second puncture guide member is generally used to guide the puncture needle to stay on the route from puncture point B to puncture point O and perform puncture along the route from puncture point B to puncture point O, pierce the cortical bone, and after removing the puncture needle body, the sleeve can still stay on the route from puncture point B to puncture point O through the second puncture guide member, so that the sampling needle can pass through the sleeve to facilitate sampling of the tissue in the target area. The shape of the second puncture guide member generally matches the shape of the puncture needle (for example, the sleeve of the puncture needle), and it is generally a cylinder. The fact that an opening is provided on the side of the second puncture guide member facing the sliding groove generally means that the side wall of the second puncture guide member close to the sliding groove is missing, and the size of its opening generally matches the sizes of the sliding groove and the puncture needle, so that after the puncture needle is removed from the opening of the first puncture guide member, the puncture needle can be moved into the second puncture guide member through the opening of the second puncture guide member, and the puncture needle can be guided by the columnar structure on the other side thereof. The second puncture guide member has a certain length in its extending direction. For example, the length of the second puncture guide member can be 10-20 mm.

[0080] In the present invention, the angle between the first puncture guide member and the second puncture guide member should generally not be too large to ensure that the puncture needle will not overly tug on the tissue during movement, causing unnecessary damage. For example, the angle between the first puncture guide member and the second puncture guide member can be 15-45°.

[0081] In a second aspect of the present invention, a method for preparing a percutaneous tissue puncture guide plate is provided. The method includes: preparing a percutaneous tissue puncture guide plate according to the percutaneous tissue puncture guide plate model constructed by the method for constructing a percutaneous tissue puncture guide plate model provided in the first aspect of the present invention. The method for preparing a percutaneous tissue puncture guide plate according to the said model should be known to those skilled in the art. For example, methods such as 3D printing can be used. Additionally, the material used during 3D printing can be photosensitive resin, etc.

[0082] In a third aspect of the present invention, a percutaneous tissue puncture guide plate is provided, which is constructed by the method for constructing a percutaneous tissue puncture guide plate model provided in the first aspect of the present invention, or is prepared by the method for preparing a percutaneous tissue puncture guide plate provided in the second aspect of the present invention.

[0083] As Figure 1 shown, the present invention provides a percutaneous tissue puncture guide plate, including a guide plate body 1. The guide plate body 1 further includes a first puncture hole 12, a second puncture hole 13, a sliding groove 14, and a bone landmark fitting part 11. The sliding groove 14 is located between the first puncture hole 12 and the second puncture hole 13. The guide plate body 1 is further provided with a first puncture guiding member 2 and a second puncture guiding member 3. The position of the first puncture guiding member 2 is matched with the first puncture hole 12, and an opening is provided on the side of the first puncture guiding member 2 facing the sliding groove 14. The position of the second puncture guiding member 3 is matched with the second puncture hole 13, and an opening is provided on the side of the second puncture guiding member 3 facing the sliding groove 14. When the percutaneous tissue puncture guide plate provided by the present invention is used, the percutaneous tissue puncture guide plate can be attached to the skin surface. A puncture needle (for example, the bone marrow biopsy needle as described above) can first enter through the first puncture hole 12 and be guided to the target point (for example, the puncture point O as described above) on the cortical bone surface through the first puncture guiding member 2, thereby forming a certain support. Then, by utilizing the support of the target point on the cortical bone surface and the ductility of the surrounding tissues, the puncture needle can be slid from the path guided by the first puncture hole 12 and the first puncture guiding member 2 to the path guided by the second puncture hole 13 and the second puncture guiding member 3. Subsequently, the cortical bone can be punctured through the puncture needle, the puncture needle body can be removed while still maintaining the sleeve in the path guided by the second puncture hole 13 and the second puncture guiding member 3, and then the target area can be sampled through the sleeve.

[0084] The percutaneous tissue puncture guide plate provided by the present invention is generally applicable to tissues with a large volume and deep location. For example, it can be pelvic tissue. The target tissue is usually a diseased tissue. For example, it can be a tumor tissue. The diseased area can usually be determined based on imaging.

[0085] In the percutaneous tissue puncture guide plate provided by the present invention, the guide plate body 1 may include a plurality of bone landmark fitting parts 11, and the bone landmark fitting parts 11 may include an anterior superior iliac spine fitting part 111, a greater trochanter of femur fitting part 112, and an inguinal fitting part 113. Generally speaking, the guide plate body can usually extend to a plurality of bone landmarks on the body surface, and a plurality of bone landmark fitting parts can be constructed based on the plurality of bone landmarks to facilitate more accurate positioning. Those skilled in the art can select the appropriate shape of the bone landmark fitting parts. For example, the bone landmark fitting parts can be arranged around the bone landmarks or cover the surface of part or all of the bone landmarks.

[0086] In the percutaneous tissue puncture guide plate provided by the present invention, the thickness of the guide plate body 1 (including the bone landmark fitting parts) can be adjusted by those skilled in the art so as to provide appropriate support strength. For example, the thickness of the guide plate body can be 2 mm to 3 mm.

[0087] In the percutaneous tissue puncture guide plate provided by the present invention, the positions of the first puncture hole 12, the second puncture hole 13, the first puncture guide 2, and the second puncture guide 3 usually correspond to the puncture path. For example, the extension direction of the first puncture guide 2 is usually consistent with the viewing direction of the external iliac plate, and the viewing direction of the external iliac plate is usually consistent with the extension direction of the line connecting the above-mentioned puncture point O and puncture point A, that is, it can extend from the outer edge of the iliac crest and 2 - 3 cm behind the anterior superior iliac spine to the surface of the cortical bone (for example, the surface of the pelvic acetabular cortical bone). For another example, the intersection of the extension directions of the first puncture guide 2 and the second puncture guide 3 is located on the surface of the cortical bone (for example, the surface of the pelvic acetabular cortical bone). For another example, the extension direction of the second puncture guide 3 is usually consistent with the line connecting the puncture point (for example, the puncture point O as described above) on the surface of the cortical bone and the target puncture point (for example, the puncture point C as described above). The angle between the first puncture guide and the second puncture guide should usually not be too large to ensure that the puncture needle will not pull the tissue too much during movement, causing unnecessary damage. For example, the angle between the first puncture guide and the second puncture guide can be 15 - 45°.

[0088] In the percutaneous tissue puncture guide plate provided by the present invention, the size of the puncture hole can be adjusted by those skilled in the art. For example, the size of the first puncture hole and / or the second puncture hole usually corresponds to the size of the puncture needle (for example, the outer diameter of the sleeve of the puncture needle). For another example, the aperture of the first puncture hole 12 can be 2 - 3 mm, and for another example, the aperture of the second puncture hole 13 is 2 - 3 mm.

[0089] In the percutaneous tissue puncture guide plate provided by the present invention, the size of the puncture guiding member should be adjustable for those skilled in the art. It is usually matched with the shape of the puncture needle (for example, the sleeve of the puncture needle). For example, the length of the first puncture guiding member 2 (i.e., the dimensional length in its extending direction) is 10 - 20 mm. For another example, the length of the second puncture guiding member 3 (i.e., the dimensional length in its extending direction) is 10 - 20 mm. For yet another example, the shape of the first puncture guiding member 2 and / or the second puncture guiding member 3 is usually a cylinder. The shape of the first puncture guiding member is usually matched with the shape of the puncture needle (for example, the sleeve of the puncture needle), and it is usually a cylinder. An opening is provided on one side of the first puncture guiding member 2 facing the sliding groove 14, which usually means that the side wall of the first puncture guiding member 2 close to the sliding groove 14 is missing. The size of the opening is usually matched with the sizes of the sliding groove and the puncture needle. Thus, during puncture, the guiding of the puncture needle can be achieved by using the cylindrical structure on one side thereof. And when it is necessary to slide the puncture needle, the puncture needle can be moved out from the opening of the first puncture guiding member 2. An opening is provided on one side of the second puncture guiding member 3 facing the sliding groove 14, which usually means that the side wall of the second puncture guiding member 3 close to the sliding groove 14 is missing. The size of the opening is usually matched with the sizes of the sliding groove and the puncture needle. Thus, after the puncture needle is moved out from the opening of the first puncture guiding member 2, the puncture needle can be moved into the second puncture guiding member 3 through the opening of the second puncture guiding member 3, and the guiding of the puncture needle can be achieved by using the cylindrical structure on the other side thereof.

[0090] In the percutaneous tissue puncture guide plate provided by the present invention, the sliding groove is located on the guide plate body and connects the first puncture hole and the second puncture hole. The size of the sliding groove 14 is usually matched with the first puncture hole 12 and / or the second puncture hole 13, so that the puncture needle can smoothly slide from the first puncture hole to the second puncture hole. The sliding groove preferably can extend linearly, so as to avoid overly driving the patient's tissue. In the extending direction thereof, the length of the sliding groove can be 2 - 5 cm.

[0091] In the percutaneous tissue puncture guide plate provided by the present invention, those skilled in the art can select appropriate materials to construct the puncture guide plate. For example, the material of the puncture guide plate can be photosensitive resin.

[0092] The fourth aspect of the present invention provides a computer-readable storage medium, on which a computer program is stored. When the program is executed by a processor, it implements the steps of the method for constructing the percutaneous tissue puncture guide plate model provided in the first aspect of the present invention, or the steps of the method for preparing the percutaneous tissue puncture guide plate provided in the second aspect of the present invention.

[0093] The fifth aspect of the present invention provides a device, including: a processor and a memory, where the memory is used to store a computer program, and the processor is used to execute the computer program stored in the memory, so that the device executes the steps of the method for constructing a percutaneous tissue puncture guide plate model provided in the first aspect of the present invention, or the steps of the method for preparing a percutaneous tissue puncture guide plate model provided in the second aspect of the present invention.

[0094] The sixth aspect of the present invention provides a device, which may include:

[0095] A three-dimensional model providing module, configured to provide a three-dimensional model of the puncture site, where the three-dimensional model includes a puncture point O and a target puncture point C, the puncture point O is located on the surface of the pelvic acetabular cortical bone, and the puncture point C is located in the puncture target area;

[0096] A puncture point A obtaining module, configured to obtain a puncture point A based on the puncture point O, where the puncture point A is located on the outer edge of the iliac crest and 2 - 3 cm behind the anterior superior iliac spine;

[0097] A puncture point B obtaining module, configured to obtain a puncture point B based on the puncture point O and the puncture point C, where the puncture point B is the intersection of the line connecting the puncture point O and the puncture point C and the body surface;

[0098] A guide plate body constructing module, configured to construct a guide plate body based on the puncture point A and the puncture point B, the guide plate body covers the skin surface, the guide plate body includes a first puncture hole and a second puncture hole, and the positions of the first puncture hole and the second puncture hole respectively match the positions of the puncture point A and the puncture point B;

[0099] A sliding groove constructing module, configured to construct a sliding groove on the guide plate body based on the puncture point A and the puncture point B, and the sliding groove connects the first puncture hole and the second puncture hole;

[0100] A first puncture guiding member constructing module, configured to construct a first puncture guiding member based on the puncture point A, and the extending direction of the first puncture guiding member is consistent with the line connecting the puncture point A and the puncture point O;

[0101] A second puncture guiding member constructing module, configured to construct a second puncture guiding member based on the puncture point B, and the extending direction of the second puncture guiding member is consistent with the line connecting the puncture point C and the puncture point O.

[0102] Optionally, it further includes: a bony landmark fitting part constructing module, configured to construct a bony landmark fitting part based on bony landmarks, and preferably, the bony landmark fitting part is selected from the anterior superior iliac spine fitting part, the greater trochanter of the femur fitting part, and the inguinal fitting part.

[0103] In the present invention, the operating principles of the various modules in the above device can refer to the construction method of the percutaneous tissue puncture guide plate model and / or the preparation method of the percutaneous tissue puncture guide plate as described above, and will not be elaborated herein.

[0104] The percutaneous tissue puncture guide plate provided by the present invention can guide the puncture surgery of deep parts, take into account the surgical approach, reduce the contamination of surrounding tissues, reduce intraoperative fluoroscopy, reduce the puncture failure rate, assist in the precise positioning of tumor lesions during the operation, provide convenience for puncture, shorten the puncture time, and has good industrialization prospects.

[0105] The following uses specific specific examples to illustrate the implementation manners of the present invention. Those skilled in the art can easily understand the other advantages and effects of the present invention from the content disclosed in this specification. The present invention can also be implemented or applied through other different specific implementation manners. Various details in this specification can also be modified or changed based on different viewpoints and applications without departing from the spirit of the present invention.

[0106] Example 1

[0107] Import the thin-slice CT and MRI data of the patient's pelvis containing tumor lesions into the image reconstruction software (medraw, mimics) to perform three-dimensional reconstruction of the surgical area and determine the tumor range. Determine the puncture point O on the surface of the pelvic acetabular cortical bone, and through the ilium, in the perspective direction parallel to and close to the outer plate of the ilium, determine the projection point A of this puncture point on the body surface (i.e., puncture point A), and this projection point is the needle insertion point. Determine the area with the strongest tumor lesion activity through imaging, and define this point as the lesion core point C (i.e., puncture point C). Connect the puncture point O on the bone surface to generate the connection line OC, and extend the connection line OC to intersect the body surface at puncture point B;

[0108] Design a percutaneous puncture guide plate in the three-dimensional reconstruction software according to the spatial position of the tumor in combination with the available bony landmark points and body surface morphological features. The guide plate extends to the anterior superior iliac spine, greater trochanter of the femur, and groin, and includes an anterior superior iliac spine fitting part, a greater trochanter of the femur fitting part, and a groin fitting part. Among them, the groin fitting part covers the surface of the groin, and the anterior superior iliac spine fitting part and the greater trochanter of the femur fitting part are arranged around the bony landmark points. The thickness of the guide plate is 2 mm;

[0109] Based on the guide plate model, determine two puncture holes on the guide plate along the OA and OB directions, and construct a sliding groove between the two puncture holes. At the same time, construct two guide columns at the corresponding positions of the puncture holes along the OA and OB directions, and the missing parts are on the sides facing each other of the two guide columns.

[0110] Import the STL file of the designed pelvic tumor puncture guide plate into a 3D printing device, use photosensitive resin to print the puncture guide plate, and after printing, sterilize and package it.

[0111] The use of this surgical guide plate during the operation effectively saves the operation time. After placing the disinfected guide plate in the surgical area, puncture can be directly carried out, and the surgical puncture is more accurate, reducing the intraoperative fluoroscopy time and avoiding excessive radiation to the operator. Generally, the operation time is reduced by about 70%, and at the same time, the surgical risk of the patient is also reduced.

[0112] In summary, the present invention effectively overcomes various disadvantages in the prior art and has high industrial utilization value.

[0113] The above embodiments are only illustrative of the principles and effects of the present invention and are not intended to limit the present invention. Any person familiar with this technology can modify or change the above embodiments without departing from the spirit and scope of the present invention. Therefore, all equivalent modifications or changes made by those with ordinary knowledge in the technical field without departing from the spirit and technical idea disclosed by the present invention should still be covered by the claims of the present invention.

Claims

1. A construction method of a percutaneous pelvic lesion tissue puncture guide plate model, comprising: Providing a three-dimensional model of the puncture site, the three-dimensional model including a puncture point O and a target puncture point C, the puncture point O being located on the cortical bone surface, and the puncture point C being located in the puncture target area; Obtaining a puncture point A based on the puncture point O, the puncture point A being located on the outer edge of the iliac crest and 2-3 cm behind the anterior superior iliac spine; Obtaining a puncture point B based on the puncture point O and the puncture point C, the puncture point B being the intersection of the line connecting the puncture point O and the puncture point C with the body surface; Constructing a guide plate body based on the puncture point A and the puncture point B, the guide plate body covering the skin surface, the guide plate body including a first puncture hole and a second puncture hole, the positions of the first puncture hole and the second puncture hole respectively corresponding to the positions of the puncture point A and the puncture point B; Constructing a sliding groove based on the puncture point A and the puncture point B, the sliding groove being located on the guide plate body and connecting the first puncture hole and the second puncture hole; Constructing a first puncture guide member based on the puncture point A, the extending direction of the first puncture guide member being consistent with the line connecting the puncture point A and the puncture point O, and an opening being provided on the side of the first puncture guide member facing the sliding groove; Constructing a second puncture guide member based on the puncture point B, the extending direction of the second puncture guide member being consistent with the line connecting the puncture point C and the puncture point O, and an opening being provided on the side of the second puncture guide member facing the sliding groove.

2. The construction method according to claim 1, wherein The puncture point O is located on the cortical bone surface of the acetabulum; And / or, the specific method of constructing the guide plate body based on the puncture point A and the puncture point B is: constructing a guide plate body reference plane based on the skin surface including the puncture point A and the puncture point B, and constructing the guide plate body based on the guide plate body reference plane; And / or, the guide plate body extends to the bony landmark points on the body surface; And / or, the thickness of the guide plate body is 2 mm - 3 mm.

3. The construction method according to claim 2, wherein The tissue is tumor tissue; The bony landmark points are selected from one or more combinations of the anterior superior iliac spine, the greater trochanter of the femur, and the inguinal region.

4. The construction method according to claim 1, characterized in that, It further includes constructing a bony landmark point fitting portion based on the bony landmark points.

5. The construction method according to claim 4, characterized in that, The bony landmark point fitting portion is selected from one or more combinations of the anterior superior iliac spine fitting portion, the greater trochanter of the femur fitting portion, and the inguinal region fitting portion.

6. The construction method according to claim 1, characterized in that, The aperture of the first puncture hole is 3 - 5 mm, and the aperture of the second puncture hole is 3 - 5 mm; And / or, the length of the first puncture guide member is 10 - 20 mm, and the length of the second puncture guide member is 10 - 20 mm; And / or, the included angle between the first puncture guide member and the second puncture guide member is 15 - 45°; 7. The construction method according to claim 1, wherein The size of the sliding groove is matched with the first puncture hole and / or the second puncture hole; And / or, the sliding groove extends linearly.

8. A method for preparing a percutaneous tissue puncture guide plate, the method comprising: Preparing a percutaneous tissue puncture guide plate from the percutaneous tissue puncture guide plate model constructed according to the construction method of the percutaneous pelvic lesion tissue puncture guide plate model according to any one of claims 1 - 7.

9. A percutaneous tissue puncture guide plate, which is obtained by constructing according to the method for constructing a percutaneous pelvic lesion tissue puncture guide plate model described in any one of claims 1-7, or is obtained by preparing according to the method for preparing a percutaneous tissue puncture guide plate described in claim 8.

10. A computer-readable storage medium having a computer program stored thereon, characterized in that, When the program is executed by a processor, it implements the steps of the method for constructing a percutaneous pelvic lesion tissue puncture guide plate model described in any one of claims 1-7, or the steps of the method for preparing a percutaneous tissue puncture guide plate described in claim 8.

11. An apparatus for preparing a percutaneous tissue puncture guide plate, comprising: A processor and a memory, the memory is used for storing a computer program, and the processor is used for executing the computer program stored in the memory, so that the device executes the steps of the method for constructing a percutaneous pelvic lesion tissue puncture guide plate model described in any one of claims 1-7, or the steps of the method for preparing a percutaneous tissue puncture guide plate model described in claim 8.

12. A device for preparing a percutaneous tissue puncture guide plate, the device comprising: A three-dimensional model providing module, configured to provide a three-dimensional model of the part to be punctured, the three-dimensional model including a puncture point O and a target puncture point C, the puncture point O is located on the surface of the pelvic acetabular cortical bone, and the puncture point C is located in the puncture target area; A puncture point A obtaining module, configured to obtain a puncture point A based on the puncture point O, the puncture point A is located on the outer edge of the iliac crest and 2-3 cm behind the anterior superior iliac spine; A puncture point B obtaining module, configured to obtain a puncture point B based on the puncture point O and the puncture point C, the puncture point B is the intersection of the line connecting the puncture point O and the puncture point C and the body surface; A guide plate body constructing module, configured to construct a guide plate body based on the puncture point A and the puncture point B, the guide plate body covers the skin surface, the guide plate body includes a first puncture hole and a second puncture hole, and the positions of the first puncture hole and the second puncture hole respectively cooperate with the positions of the puncture point A and the puncture point B; A sliding groove constructing module, configured to construct a sliding groove on the guide plate body based on the puncture point A and the puncture point B, the sliding groove connects the first puncture hole and the second puncture hole; A first puncture guiding member constructing module, configured to construct a first puncture guiding member based on the puncture point A, and the extending direction of the first puncture guiding member is consistent with the line connecting the puncture point A and the puncture point O; A second puncture guiding member constructing module, configured to construct a second puncture guiding member based on the puncture point B, and the extending direction of the second puncture guiding member is consistent with the line connecting the puncture point C and the puncture point O.

13. The device according to claim 12, characterized in that, The device further includes: a bony landmark fitting part constructing module, configured to construct a bony landmark fitting part based on bony landmarks.

14. The device according to claim 13, characterized in that, The bony landmark fitting part is selected from one or a combination of an anterior superior iliac spine fitting part, a greater trochanter of femur fitting part, and an inguinal fitting part.

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